{"id":4477,"date":"2019-05-09T09:55:54","date_gmt":"2019-05-09T01:55:54","guid":{"rendered":"http:\/\/case.ntu.edu.tw\/scinarrator\/wordpress\/?p=4477"},"modified":"2019-05-16T18:36:47","modified_gmt":"2019-05-16T10:36:47","slug":"%e3%80%8a%e5%9f%ba%e5%9b%a0%e7%b7%a8%e8%bc%af%e5%a4%a7%e9%9d%a9%e5%91%bd%ef%bc%9acrispr-%e5%a6%82%e4%bd%95%e6%94%b9%e5%af%ab%e5%9f%ba%e5%9b%a0%e5%af%86%e7%a2%bc%e3%80%81%e6%8e%8c%e6%8e%a7%e6%bc%94","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/scinarrator\/?p=4477","title":{"rendered":"\u300a\u57fa\u56e0\u7de8\u8f2f\u5927\u9769\u547d\uff1aCRISPR \u5982\u4f55\u6539\u5beb\u57fa\u56e0\u5bc6\u78bc\u3001\u638c\u63a7\u6f14\u5316\u3001\u5f71\u97ff\u751f\u547d\u7684\u672a\u4f86\u300b"},"content":{"rendered":"

\"\"<\/p>\n

ISBN\uff1a9789864794805<\/p>\n

\u4f5c\u8005\uff1a Jennifer A. Doudna, Samuel H. Sternberg<\/p>\n

\u8b6f\u8005\uff1a \u5468\u6c9b\u90c1<\/p>\n

\u51fa\u7248\u793e\uff1a\u5929\u4e0b\u6587\u5316<\/p>\n

\u672c\u66f8\u7c21\u4ecb<\/strong><\/span><\/p>\n

\n
\n
\u5fae\u5c0f\u7d30\u83cc\u7684\u514d\u75ab\u7cfb\u7d71\uff0c\u5982\u4f55\u8b8a\u6210\u5f37\u5927\u7684\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\uff0c
\n\u9019\u9805\u79d1\u6280\u53c8\u5982\u4f55\u6210\u70ba\u638c\u63a7\u751f\u7269\u6f14\u5316\u7684\u529b\u91cf\uff0c
\nCRISPR\u9769\u547d\u5373\u5c07\u5e36\u4f86\u524d\u6240\u672a\u898b\u7684\u5f71\u97ff\uff0c\u6211\u5011\u6e96\u5099\u597d\u4e86\u55ce\uff1f<\/strong><\/div>\n<\/div>\n
CRISPR\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\u5e36\u4f86\u7684\u9769\u547d\u6b63\u5728\u5168\u9762\u5c55\u958b\uff0c
\n\u6ce2\u53ca\u5730\u7403\u4e0a\u7684\u6240\u6709\u751f\u547d\uff0c\u4f60\u6211\u90fd\u7121\u6cd5\u7f6e\u8eab\u4e8b\u5916\u3002<\/strong><\/p>\n

CRISPR\u539f\u672c\u662f\u81ea\u7136\u754c\u4e2d\u7d30\u83cc\u7684\u4e00\u7a2e\u514d\u75ab\u7cfb\u7d71\uff0c\u80fd\u9396\u5b9a\u5165\u4fb5\u7684\u75c5\u6bd2\uff0c\u526a\u788e\u5b83\u5011\u7684DNA\u3002\u7d93\u904e\u79d1\u5b78\u5bb6\u7684\u89e3\u5bc6\uff0c\u5229\u7528\u9019\u7a2e\u7cfb\u7d71\u7684\u5b9a\u4f4d\u8207\u5207\u5272\u529f\u80fd\uff0c\u628a\u5b83\u8b8a\u6210\u6700\u7c21\u55ae\u3001\u4fbf\u5b9c\u53c8\u6709\u6548\u7684\u57fa\u56e0\u7de8\u8f2f\u5de5\u5177\u3002\u5982\u4eca\u6211\u5011\u5e7e\u4e4e\u53ef\u4ee5\u7528CRISPR\u4f86\u7de8\u8f2f\u6bcf\u4e00\u7a2e\u751f\u7269DNA\u4e0a\u7684\u5b57\u6bcd\uff0c\u5230\u4e86\u96a8\u5fc3\u6240\u6b32\u7684\u5730\u6b65\u3002<\/p>\n

\u9019\u9805\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\u554f\u4e16\u624d\u77ed\u77ed\u5e7e\u5e74\u7684\u6642\u9593\uff0c\u5df2\u7d93\u6210\u529f\u88fd\u9020\u51fa\u80fd\u5920\u62b5\u6297\u75c5\u5bb3\u7684\u6c34\u7a3b\u3001\u7121\u6cd5\u50b3\u64ad\u7627\u75be\u7684\u868a\u5b50\u3001\u9084\u6709\u4e0d\u518d\u9577\u89d2\u7684\u725b\uff0c\u4e26\u53ef\u671b\u958b\u767c\u51fa\u6cbb\u7642\u764c\u75c7\u3001\u907a\u50b3\u75be\u75c5\u53ca\u611b\u6ecb\u75c5\u7b49\u75be\u75c5\u7684\u7642\u6cd5\u3002\u751a\u81f3\u6709\u79d1\u5b78\u5bb6\u6b63\u5728\u8b93\u6ec5\u7d55\u7684\u731b\u7341\u8c61\u5fa9\u6d3b\uff0c\u9084\u6709\u4eba\u60f3\u8981\u628a\u8a02\u88fd\u5bf5\u7269\u3001\u8a02\u88fd\u5b30\u5152\u767c\u5c55\u6210\u4e00\u9580\u7522\u696d\u3002<\/p>\n

\u73fe\u4eca\u6bcf\u4e00\u7a2e\u751f\u7269\u7684\u57fa\u56e0\u7d44\u6210\uff0c\u90fd\u662f\u9577\u9054\u5e7e\u5341\u5104\u5e74\u7684\u6f14\u5316\u5091\u4f5c\uff0c\u73fe\u5728\u900f\u904eCRISPR\uff0c\u53ea\u8981\u77ed\u77ed\u5e7e\u5929\uff0c\u5c31\u53ef\u4ee5\u5feb\u901f\u6539\u7de8\u6240\u6709\u57fa\u56e0\u3002\u4eba\u985e\u63a5\u624b\u4e86\u6f14\u5316\u7684\u529b\u91cf\uff0c\u80fd\u5920\u5de6\u53f3\u6240\u6709\u751f\u7269\u672a\u4f86\u7684\u547d\u904b\uff0c\u9019\u4f3c\u4e4e\u5e36\u4f86\u7121\u9650\u524d\u666f\uff0c\u4f46\u4e5f\u53ef\u80fd\u5e36\u4f86\u99ed\u4eba\u5371\u6a5f\uff0c\u50cf\u662f\u7121\u610f\u9593\u64f4\u5927\u907a\u50b3\u4e0d\u5e73\u7b49\uff0c\u6216\u4f7f\u4e00\u500b\u7269\u7a2e\u6d88\u5931\u3002<\/p>\n

\u9053\u7d0d\u662f\u89e3\u958bCRISPR\u6a5f\u5236\u7684\u79d1\u5b78\u5bb6\u4e4b\u4e00\uff0c\u8207\u7814\u7a76\u5925\u4f34\u53f2\u9a30\u4f2f\u683c\u5408\u529b\u5beb\u4e0b\u672c\u66f8\uff0c\u89aa\u81ea\u5c0e\u89bd\u9019\u8d9f\u9a5a\u5fc3\u52d5\u9b44\u7684\u767c\u73fe\u6b77\u7a0b\uff0c\u4ee5\u53ca\u4ee4\u4eba\u5606\u70ba\u89c0\u6b62\u7684\u79d1\u5b78\u539f\u7406\u3001\u5404\u7a2e\u5be6\u7528\u6216\u5145\u6eff\u60f3\u50cf\u529b\u7684\u61c9\u7528\uff0c\u4ee5\u53ca\u672a\u4f86\u7684\u5c55\u671b\u548c\u96b1\u6182\u3002<\/p>\n

\u5fae\u5c0f\u7d30\u83cc\u7684\u514d\u75ab\u7cfb\u7d71\uff0c\u5982\u4f55\u8b8a\u6210\u5f37\u5927\u7684\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\uff0c
\n\u9019\u9805\u79d1\u6280\u53c8\u5982\u4f55\u6210\u70ba\u638c\u63a7\u751f\u7269\u6f14\u5316\u7684\u529b\u91cf\uff0c
\nCRISPR\u9769\u547d\u5373\u5c07\u5e36\u4f86\u524d\u6240\u672a\u898b\u7684\u5f71\u97ff\uff0c\u6211\u5011\u6e96\u5099\u597d\u4e86\u55ce\uff1f<\/p>\n

\u672c\u66f8\u7279\u8272<\/strong><\/span><\/p>\n

\u9019\u662f\u7b2c\u4e00\u672c\u5c08\u9580\u4ee5CRISPR\u57fa\u56e0\u7de8\u8f2f\u70ba\u4e3b\u984c\u7684\u79d1\u666e\u66f8\u3002\u53ea\u8981\u900f\u904e\u9019\u672c\u66f8\uff0c\u5373\u53ef\u4ee5\u5c0d\u65bc\u57fa\u56e0\u7de8\u8f2f\u79d1\u6280\u8207CRISPR\u7684\u8d77\u6e90\u3001\u4f86\u9f8d\u53bb\u8108\u3001\u79d1\u5b78\u539f\u7406\u53ca\u524d\u666f\u6709\u5168\u76e4\u8a8d\u8b58\u3002<\/p>\n

\u4f5c\u8005\u9053\u7d0d\u662fCRISPR\u9818\u57df\u7684\u5e36\u982d\u8005\u4e4b\u4e00\uff0c\u53f2\u9a30\u4f2f\u683c\u4e5f\u662f\u8a72\u9818\u57df\u7684\u5c08\u5bb6\uff0c\u5f88\u5c11\u6709\u79d1\u5b78\u5bb6\u5728\u505a\u51fa\u91cd\u5927\u79d1\u5b78\u7a81\u7834\u4e4b\u5f8c\u5f88\u5feb\u5c31\u5beb\u6210\u901a\u4fd7\u8457\u4f5c\uff0c\u5c0d\u65bc\u60f3\u4e86\u89e3\u9019\u9805\u4e3b\u984c\u7684\u4eba\u4f86\u8aaa\uff0c\u9019\u672c\u66f8\u662f\u6700\u4f73\u9078\u64c7\u3002<\/p>\n

\u91cd\u91cf\u7d1a\u63a8\u85a6<\/strong><\/span><\/p>\n

\u6211\u5011\u7576\u4e0b\u6b63\u5728\u76ee\u7779CRISPR\u5e36\u4f86DNA\u79d1\u6280\u9769\u547d\u7684\u5168\u9762\u958b\u5c55\uff0c\u5b83\u5c0d\u672a\u4f86\u4e16\u754c\u7684\u5f71\u97ff\u662f\u524d\u6240\u672a\u898b\u7684\u3002\u2500\u2500\u5468\u6210\u529f\uff0c\u967d\u660e\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb\u66a8\u57fa\u56e0\u9ad4\u79d1\u5b78\u7814\u7a76\u6240\u9000\u4f11\u6559\u6388<\/p>\n<\/div>\n

\u5ef6\u4f38\u95b1\u8b80 \uff0f\u53c3\u8003\u8cc7\u6599<\/strong><\/span><\/div>\n<\/div>\n
\u25ba\u3010CASE\u8aaa\u66f8\u4eba\u3011\u57fa\u56e0\u7de8\u8f2f\u5927\u9769\u547d \u2502\u5468\u6210\u529f<\/span><\/a><\/span><\/h6>\n
\u25ba\u3010CASE\u8aaa\u66f8\u4eba\u3011\u756a\u5916\u7bc7-\u57fa\u56e0\u7de8\u8f2f\u5bf6\u5bf6\u4e8b\u4ef6<\/span><\/span><\/a><\/h6>\n
\u25ba\u3010CASE\u5716\u66f8\u9928\u3011\u300a\u57fa\u56e0\u7de8\u8f2f\u5927\u9769\u547d\u300b\u66f8\u6458-\u5947\u8349\u7570\u7378<\/a><\/span><\/span><\/h6>\n
\u25ba<\/a><\/span><\/span>\u300a\u79d1\u5b78\u6708\u520a\u300b\u57fa\u56e0\u7de8\u8f2f\u5927\u6d6a\u8972\u4f86\u2014CRISPR\u6280\u8853\u5148\u9a45\u8005\u73cd\u59ae\u4f5b\u02d9\u9053\u7d0d\u5c08\u8a2a\uff5c\u8d99\u8ed2\u7fce<\/a><\/span><\/strong><\/h6>\n","protected":false},"excerpt":{"rendered":"

ISBN\uff1a9789864794805 \u4f5c\u8005\uff1a Jennife …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[40,39,31,2],"tags":[],"class_list":["post-4477","post","type-post","status-publish","format-standard","hentry","category-40","category-39","category-31","category-2"],"views":430,"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/scinarrator\/index.php?rest_route=\/wp\/v2\/posts\/4477","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/scinarrator\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/scinarrator\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/scinarrator\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/scinarrator\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4477"}],"version-history":[{"count":17,"href":"https:\/\/case.ntu.edu.tw\/scinarrator\/index.php?rest_route=\/wp\/v2\/posts\/4477\/revisions"}],"predecessor-version":[{"id":4594,"href":"https:\/\/case.ntu.edu.tw\/scinarrator\/index.php?rest_route=\/wp\/v2\/posts\/4477\/revisions\/4594"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/scinarrator\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4477"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/scinarrator\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4477"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/scinarrator\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4477"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}