{"id":57212,"date":"2014-10-04T02:29:08","date_gmt":"2014-10-03T18:29:08","guid":{"rendered":"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/?p=57212"},"modified":"2021-10-06T16:13:28","modified_gmt":"2021-10-06T08:13:28","slug":"%e8%8a%b3%e9%a6%99%e7%92%b0%e9%85%b6%e6%8a%91%e5%88%b6%e5%8a%91aromatase-inhibitor","status":"publish","type":"post","link":"http:\/\/localhost\/%e8%8a%b3%e9%a6%99%e7%92%b0%e9%85%b6%e6%8a%91%e5%88%b6%e5%8a%91aromatase-inhibitor\/","title":{"rendered":"\u82b3\u9999\u74b0\u9176\u6291\u5236\u5291"},"content":{"rendered":"<div class=\"pf-content\"><p><span style=\"color: #ff6600;\"><strong>\u82b3\u9999\u74b0\u9176\u6291\u5236\u5291 (Aromatase Inhibitor)<\/strong><\/span><br \/>\n<span style=\"color: #008000;\"><strong>\u81fa\u5317\u5e02\u7acb\u7b2c\u4e00\u5973\u5b50\u9ad8\u7d1a\u4e2d\u5b78\u4e8c\u5e74\u7d1a\u738b\u54b8\u5a77\/\u81fa\u5317\u5e02\u7acb\u7b2c\u4e00\u5973\u5b50\u9ad8\u7d1a\u4e2d\u5b78\u5316\u5b78\u79d1\u6c5f\u6167\u7389\u8001\u5e2b<\/strong><\/span><\/p>\n<p><b>\u82b3\u9999\u74b0\u9176\u6291\u5236\u5291\u539f\u7406\uff1a<\/b><b><\/b><\/p>\n<p>\u6709\u4e9b\u4e73\u817a\u764c\u9700\u8981\u96cc\u6fc0\u7d20\u7684\u589e\u9577\u3002\u9019\u4e9b\u764c\u75c7\u5177\u6709\u96cc\u6fc0\u7d20<a title=\"\u53d7\u9ad4\uff08\u751f\u7269\u5316\u5b78\uff09\" href=\"http:\/\/en.wikipedia.org\/wiki\/Receptor_(biochemistry)\">\u53d7\u9ad4<\/a>\uff08ERS\uff09\uff0c\u6240\u4ee5\u4e5f\u88ab\u7a31\u70baER\u967d\u6027\uff0c\u5b83\u5011\u53ef\u4ee5\u88ab\u96cc\u6fc0\u7d20\u53cd\u61c9\u3002\u56e0\u70ba\u96cc\u6fc0\u7d20\u6703\u5e6b\u52a9\u4e73\u764c\u7d30\u80de\u7684\u751f\u9577\uff0c\u800c\u82b3\u9999\u74b0\u9176\u662f\u4e00\u7a2e\u5408\u6210\u96cc\u6fc0\u7d20\u7684\u9176\uff0c\u6240\u4ee5\u82b3\u9999\u74b0\u9176\u6291\u5236\u5291\u53ef\u85c9\u7531\u5e6b\u52a9\u4eba\u9ad4\u505c\u6b62\u88fd\u9020\u96cc\u6fc0\u7d20\uff0c\u9032\u800c\u7528\u4f86\u6cbb\u7642\u4e73\u764c\u3002<\/p>\n<p>\u4eba\u9ad4\u6703\u5c07\u96c4\u6027\u7d20\u8f49\u63db\u6210\u96cc\u6fc0\u7d20\uff0c\u5c24\u5176\u5c0d\u505c\u7d93\u5f8c\u5a66\u5973\u6700\u70ba\u91cd\u8981\uff0c\u56e0\u70ba\u505c\u7d93\u5f8c\uff0c\u5375\u5de2\u5df2\u4e0d\u518d\u80fd\u4f9b\u7d66\u96cc\u6027\u6fc0\u7d20\uff0c\u6545\u6b64\u7a2e\u8f49\u63db\u70ba\u505c\u7d93\u5f8c\u5a66\u5973\u96cc\u6027\u6fc0\u7d20\u4e3b\u8981\u4f86\u6e90\u3002\u9019\u7a2e\u8f49\u63db\u9700\u8981\u4e00\u7a2e\u540d\u70ba\u82b3\u9999\u74b0\u9176\u7684\u86cb\u767d\u8cea\uff0c\u96c4\u6027\u7d20\u6703\u63a5\u5408\u5728\u9019\u500b\u86cb\u767d\u8cea\u4e0a\u9762\u7684\u53d7\u5668\uff0c\u9032\u4e00\u6b65\u8f49\u8b8a\u6210\u96cc\u6fc0\u7d20\u3002\u82b3\u9999\u74b0\u9176\u6291\u5236\u5291\u5247\u6703\u963b\u65b7\u82b3\u9999\u74b0\u9176\u4e0a\u9762\u7684\u63a5\u53d7\u5668\u4f4d\u7f6e\uff0c\u8b93\u96c4\u6027\u7d20\u7121\u6cd5\u9760\u8fd1\uff0c\u56e0\u800c\u505c\u6b62\u96cc\u6fc0\u7d20\u7684\u88fd\u9020\uff0c\u4e14\u7576\u82b3\u9999\u74b0\u9176\u6291\u5236\u5291\u8207\u82b3\u9999\u74b0\u9176\u7684\u53d7\u5668\u7d50\u5408\u6642\uff0c\u6703\u6c38\u9060\u5730\u6539\u8b8a\u9019\u500b\u86cb\u767d\u8cea\uff0c\u800c\u7522\u751f\u8b8a\u8cea\uff0c\u85c9\u6b64\u6c38\u4e45\u201c\u95dc\u9589\u201d\u5b83\u7684\u529f\u80fd\uff0c\u4f7f\u82b3\u9999\u74b0\u9176\u6c38\u9060\u7121\u6cd5\u518d\u88fd\u9020\u96cc\u6fc0\u7d20\u3002<!--more--><\/p>\n<div id=\"attachment_72111\" style=\"width: 610px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p1.png\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-72111\" class=\"wp-image-72111\" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p1.png\" alt=\"57212_p1\" width=\"600\" height=\"203\" srcset=\"http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p1.png 783w, http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p1-300x101.png 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><p id=\"caption-attachment-72111\" class=\"wp-caption-text\">(\u5716\u3127)\u82b3\u9999\u74b0\u9176\u5c07\u776a\u56fa\u916e\u8f49\u63db\u70ba\u96cc\u4e8c\u9187<\/p><\/div>\n<div id=\"attachment_72112\" style=\"width: 610px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p2.png\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-72112\" class=\"wp-image-72112\" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p2.png\" alt=\"57212_p2\" width=\"600\" height=\"183\" srcset=\"http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p2.png 1015w, http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p2-300x91.png 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><p id=\"caption-attachment-72112\" class=\"wp-caption-text\">(\u5716\u4e8c)\u82b3\u9999\u74b0\u9176\u7684\u50ac\u5316\u6a5f\u5236(\u96c4\u70ef\u4e8c\u916e\u2192\u96cc\u916e)\u00a0\u00a0<\/p><\/div>\n<p><b>\u5e38\u7528\u82b3\u9999\u74b0\u9176\u6291\u5236\u5291\uff1a<\/b><b><\/b><\/p>\n<p><b>\u4f9d\u897f\u7f8e\u5766<\/b><b>Exemestane<\/b><b>\uff08\u5546\u54c1\u540d\u963f\u8afe\u65b0\uff09<\/b><b><\/b><\/p>\n<p>\u9069\u7528\uff1aER\u967d\u6027\u4e73\u817a\u764c\u9664\u4e86\u624b\u8853\u548c\/\u6216\u653e\u7642\u5728\u7d55\u7d93\u5f8c\u5a66\u5973\u53e3\u670d\u985e\u56fa\u9187\u985e\u82b3\u9999\u9176\u6291\u88fd\u5291\u3002<\/p>\n<p>\u4f5c\u7528\uff1a\u4f9d\u897f\u7f8e\u5766\u662f\u4e00\u7a2e\u4e0d\u53ef\u9006\u7684\uff0c\u753e\u9ad4\u985e\u82b3\u9999\u74b0\u9176\u6ec5\u6d3b\u5291\uff0c\u7d50\u69cb\u4e0a\u8207\u5929\u7136\u96c4\u6027\u6fc0\u7d20<a title=\"\u96c4\u70ef\u4e8c\u916e\" href=\"http:\/\/en.wikipedia.org\/wiki\/Androstenedione\">\u96c4\u70ef\u4e8c\u916e<\/a>\u76f8\u4f3c\u3002\u6b64\u85e5\u7269\u4f5c\u7528\u6642\uff0c\u6703\u53d6\u4ee3\u96c4\u70ef\u4e8c\u916e(androstenedione)\uff0c\u4f5c\u70ba\u82b3\u9999\u74b0\u9176\u7684\u5047\u53cd\u61c9\u7269\uff0c\u4e26\u9032\u884c\u8655\u7406\uff0c\u4e0d\u53ef\u9006\u5730\u8207\u9176\u7684\u6d3b\u6027\u90e8\u4f4d\u7d50\u5408\u5c0e\u81f4\u5176\u5931\u6d3b\u6027\uff0c\u5176\u6548\u679c\u4e5f\u88ab\u7a31\u70ba\u201c\u00a0<a title=\"\u6291\u5236\u81ea\u6bba\" href=\"http:\/\/en.wikipedia.org\/wiki\/Suicide_inhibition\">\u81ea\u6bba\u6291\u88fd\u4f5c\u7528<\/a>\u00a0\u201c\u3002\u901a\u904e\u5728\u7d50\u69cb\u4e0a\u76f8\u4f3c\u65bc\u9176\u7684\u76ee\u6a19\uff0c\u4f7f\u4f9d\u897f\u7f8e\u5766\u6c38\u4e45\u7d50\u5408\u5230\u9176\u4e0a\uff0c\u9632\u6b62\u5b83\u5011\u8f49\u63db\u96c4\u6fc0\u7d20\u8f49\u8b8a\u70ba\u96cc\u6fc0\u7d20\u3002<\/p>\n<p>\u526f\u4f5c\u7528\uff1a\u6f6e\u71b1\u3001\u5641\u5fc3\u3001\u5931\u7720\u3001\u6291\u9b31\u3001\u982d\u75db\u3001\u7729\u6688\u3001\u75bc\u75db\u3001\u76ae\u75b9\u3001\u8179\u75db\u3001\u53ad\u98df\u3001\u5614\u5410\u3001\u6291\u9b31\u3001\u812b\u9aee\u3001\u5168\u8eab\u6216\u4e0b\u80a2\u6c34\u816b\u3001\u4fbf\u79d8\u548c\u6d88\u5316\u4e0d\u826f\u7b49\u3002<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"209\">\u00a0<a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p3.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-72115\" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p3.png\" alt=\"57212_p3\" width=\"275\" height=\"220\" srcset=\"http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p3.png 358w, http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p3-300x240.png 300w\" sizes=\"auto, (max-width: 275px) 100vw, 275px\" \/><\/a><\/td>\n<td width=\"209\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p3-2.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-72113\" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p3-2.png\" alt=\"57212_p3-2\" width=\"275\" height=\"185\" srcset=\"http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p3-2.png 350w, http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p3-2-300x202.png 300w\" sizes=\"auto, (max-width: 275px) 100vw, 275px\" \/><\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" colspan=\"2\" width=\"418\">\u00a0(\u5716\u4e09) Exemestane(\u5de6)\u3001Androstenedione(\u53f3)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong><a title=\"\u963f\u90a3\u66f2\u5511\" href=\"http:\/\/en.wikipedia.org\/wiki\/Anastrozole\">\u963f\u90a3\u66f2\u5511<\/a>\uff08\u745e\u5be7\u5f97\uff09Anastrozole \u3001<a title=\"\u4f86\u66f2\u5511\" href=\"http:\/\/en.wikipedia.org\/wiki\/Letrozole\">\u4f86\u66f2\u5511<\/a>\uff08\u5f17\u9686\uff09Letrozole<\/strong><\/p>\n<p>\u9069\u7528\uff1aER\u967d\u6027\u4e73\u817a\u764c\u9664\u4e86\u624b\u8853\u548c\/\u6216\u653e\u7642\u5728\u7d55\u7d93\u5f8c\u5a66\u5973\u53e3\u670d\u975e\u985e\u56fa\u9187\u985e\u82b3\u9999\u9176\u6291\u88fd\u5291\u3002<\/p>\n<p>\u4f5c\u7528\uff1a\u900f\u904e\u7af6\u722d\u6027\u6291\u5236\uff0c\u963f\u90a3\u66f2\u5511\u548c\u4f86\u66f2\u5511\u4ee5\u53ef\u9006\u7684\u65b9\u5f0f\u7d50\u5408\u5230<a title=\"\u82b3\u9999\" href=\"http:\/\/en.wikipedia.org\/wiki\/Aromatase\">\u82b3\u9999<\/a>\u74b0\u9176\u4e0a\u7684\u53d7\u5668\uff0c\u6291\u5236\u96c4\u6027\u6fc0\u7d20\u8f49\u5316\u70ba\u96cc\u6fc0\u7d20\u3002<\/p>\n<p>\u526f\u4f5c\u7528\uff1a<a title=\"\u6f6e\u71b1\" href=\"http:\/\/en.wikipedia.org\/wiki\/Hot_flash\">\u6f6e\u71b1<\/a>\u3001\u95dc\u7bc0\u75db\u548c<a title=\"\u75b2\u52de\uff08\u91ab\u7642\uff09\" href=\"http:\/\/en.wikipedia.org\/wiki\/Fatigue_(medical)\">\u75b2\u52de<\/a>\u3002\u9577\u671f\u4f7f\u7528\u53ef\u80fd\u5c0e\u81f4\u9aa8\u8cea\u758f\u9b06\u75c7<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"209\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p4-1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-72114 aligncenter\" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p4-1.png\" alt=\"57212_p4-1\" width=\"300\" height=\"210\" srcset=\"http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p4-1.png 421w, http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p4-1-300x209.png 300w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/td>\n<td style=\"text-align: center;\" width=\"209\">\u00a0<a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p4-2.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-72116\" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/10\/57212_p4-2.png\" alt=\"57212_p4-2\" width=\"300\" height=\"186\" srcset=\"http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p4-2.png 487w, http:\/\/localhost\/wp-content\/uploads\/2014\/10\/57212_p4-2-300x186.png 300w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" colspan=\"2\" width=\"418\">\u00a0(\u5716\u56db) Anastrozole<b>(<\/b><b>\u5de6)<\/b> \u3001Letrozole<b>(<\/b><b>\u53f3)<\/b><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u764c\u75c7\u5df2\u7d93\u87ec\u806f\u570b\u4eba\u5341\u5927\u6b7b\u56e0\u4e4b\u9996\u6578\u5e74\u4e4b\u4e45\uff0c\u800c\u4e73\u764c\u53ca\u5176\u4f75\u767c\u75c7\u53c8\u662f\u5973\u6027\u6700\u5927\u7684\u5929\u6575\uff0c\u56e0\u6b64\uff0c\u6297\u764c\u85e5\u7269\u7684\u958b\u767c\u5df2\u7d93\u662f\u523b\u4e0d\u5bb9\u7de9\u3002\u6709\u9451\u65bc\u50b3\u7d71\u5316\u7642\uff0c\u5c07\u9023\u540c\u764c\u7d30\u80de\u5468\u906d\u7684\u6b63\u5e38\u7d30\u80de\u4e00\u4f75\u6bba\u6b7b\uff0c\u5e38\u5c0e\u81f4\u75c5\u4eba\u6389\u9aee\u53ca\u4e0d\u9069\uff0c\u6a19\u9776\u85e5\u7269\u548c\u8cc0\u723e\u8499\u7642\u6cd5\u4fbf\u61c9\u904b\u800c\u751f\uff0c\u9019\u7a2e\u53ef\u5c08\u4e00\u6027\u91dd\u5c0d\u764c\u7d30\u80de\u9032\u884c\u6cbb\u7642\u7684\u65b9\u6cd5\uff0c\u4e0d\u50c5\u53ef\u6e1b\u5c11\u75c5\u60a3\u8eab\u9ad4\u7684\u4e0d\u9069\uff0c\u9084\u53ef\u63d0\u9ad8\u5b58\u6d3b\u7387\uff0c\u60df\u9808\u6ce8\u610f\u7684\u662f\u5176\u6240\u5e36\u4f86\u7684\u526f\u4f5c\u7528\uff0c\u76ee\u524d\u7684\u85e5\u7269\u958b\u767c\uff0c\u5c07\u671d\u5411\u80fd\u7dad\u6301\u5176\u7642\u6548\uff0c\u4e26\u964d\u4f4e\u5c0d\u4eba\u9ad4\u7684\u526f\u4f5c\u7528\u9081\u9032\uff0c\u82e5\u80fd\u6709\u6240\u6210\u679c\uff0c\u5fc5\u5b9a\u80fd\u70ba\u8a31\u591a\u764c\u75c7\u75c5\u60a3\u5e36\u4f86\u5e0c\u671b\u4e4b\u5149\u3002<\/p>\n<hr \/>\n<p><strong>\u53c3\u8003\u8cc7\u6599<\/strong><\/p>\n<ul>\n<li>\u300a\u89c0\u5ff5\u5316\u5b78 IV\u300b\u00a0 \u8607\u5361\u5947\u00a0 \u8457\u00a0\u00a0\u00a0 \u674e\u5343\u6bc5\u00a0 \u8b6f\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0 p.105~p.115\u00a0\u00a0\u00a0 2006<\/li>\n<li>\u4e73\u764c\u885b\u6559\u7db2\u00a0 http:\/\/www.pfizer.com.tw\/mediacalinfo\/2010\/08\/Page03.asp<\/li>\n<li>\u65b0\u85e5\u4fe1\u606f\u7db2\u00a0 <a href=\"http:\/\/www.newdruginfo.cn\/Html\/drugknodg\/caution\/3338.html\">http:\/\/www.newdruginfo.cn\/Html\/drugknodg\/caution\/3338.html<\/a><\/li>\n<li>\u7dad\u57fa\u767e\u79d1&#8212;-\u4e73\u764c\u00a0 <a href=\"http:\/\/zh.wikipedia.org\/zh-tw\/%E4%B9%B3%E7%99%8C\">http:\/\/zh.wikipedia.org\/zh-tw\/%E4%B9%B3%E7%99%8C<\/a><\/li>\n<li>\u7dad\u57fa\u767e\u79d1&#8212;- Exemestane\u00a0 <a href=\"http:\/\/en.wikipedia.org\/wiki\/Exemestane\">http:\/\/en.wikipedia.org\/wiki\/Exemestane<\/a><\/li>\n<li>\u7dad\u57fa\u767e\u79d1&#8212;- Aromatase_inhibitor\u00a0 <a href=\"http:\/\/en.wikipedia.org\/wiki\/Aromatase_inhibitor\">http:\/\/en.wikipedia.org\/wiki\/Aromatase_inhibitor<\/a><\/li>\n<li>\u7dad\u57fa\u767e\u79d1&#8212;- Anastrozole\u00a0 http:\/\/en.wikipedia.org\/wiki\/Anastrozole<\/li>\n<li>\u7dad\u57fa\u767e\u79d1&#8212;- Letrozole\u00a0 <a href=\"http:\/\/en.wikipedia.org\/wiki\/Letrozole\">http:\/\/en.wikipedia.org\/wiki\/Letrozole<\/a><\/li>\n<li>\u7dad\u57fa\u767e\u79d1&#8212;- Aromatase\u00a0 <a href=\"http:\/\/en.wikipedia.org\/wiki\/Aromatase\">http:\/\/en.wikipedia.org\/wiki\/Aromatase<\/a><\/li>\n<li>\u5982\u4f55\u9078\u64c7\u4e73\u764c \u6297\u8377\u723e\u8499\u6cbb\u7642.pdf\u00a0 \u8607\u9032\u6210 \u91ab\u5b78\u535a\u58eb\u00a0 2012\/12\/29<\/li>\n<\/ul>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u82b3\u9999\u74b0\u9176\u6291\u5236\u5291 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