{"id":53372,"date":"2014-05-20T03:26:39","date_gmt":"2014-05-19T19:26:39","guid":{"rendered":"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/?p=53372"},"modified":"2021-10-06T16:18:11","modified_gmt":"2021-10-06T08:18:11","slug":"%e8%b6%85%e5%a4%9a%e8%83%bd%e5%88%86%e5%8c%96%e6%80%a7%ef%bc%88pluripotency%ef%bc%89%ef%bc%8d%e5%88%86%e5%8c%96%e6%bd%9b%e8%83%bd-%e4%b8%8b","status":"publish","type":"post","link":"http:\/\/localhost\/%e8%b6%85%e5%a4%9a%e8%83%bd%e5%88%86%e5%8c%96%e6%80%a7%ef%bc%88pluripotency%ef%bc%89%ef%bc%8d%e5%88%86%e5%8c%96%e6%bd%9b%e8%83%bd-%e4%b8%8b\/","title":{"rendered":"\u8d85\u591a\u80fd\u5206\u5316\u6027\uff08pluripotency\uff09\uff0d\u5206\u5316\u6f5b\u80fd  -\u4e0b"},"content":{"rendered":"<div class=\"pf-content\"><p><span style=\"color: #ff6600;\"><strong>\u8d85\u591a\u80fd\u5206\u5316\u6027\uff08pluripotency\uff09\uff0d\u5206\u5316\u6f5b\u80fd -\u4e0b<\/strong><\/span><br \/>\n<span style=\"color: #008000;\"><strong>\u81fa\u4e2d\u5e02\u96d9\u5341\u570b\u4e2d\u81ea\u7136\u9818\u57df\u738b\u6dd1\u537f\u6559\u5e2b<\/strong><\/span><\/p>\n<p>\u9023\u7d50\uff1a<a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/?p=53364\">\u8d85\u591a\u80fd\u5206\u5316\u6027\uff08Pluripotency\uff09\uff0d\u4f86\u6e90\u8207\u61c9\u7528 \u4e2d<\/a><\/p>\n<ul>\n<li><span style=\"color: #000080;\">\u5e79\u7d30\u80de\u53ef\u4f9d\u5206\u5316\u6f5b\u80fd\u7684\u5dee\u7570\u5206\u985e<\/span><\/li>\n<\/ul>\n<p>\u7814\u7a76\u5206\u96e2\u51fa\u4e0d\u540c\u968e\u6bb5\u7684\u5e79\u7d30\u80de\uff0c\u79d1\u767c\u73fe\u5177\u6709\u4e0d\u540c\u7684\u7d30\u80de\u6f5b\u80fd\uff08cell potency\uff09\uff0c\u5373\u5206\u5316\u6210\u4e0d\u540c\u985e\u578b\u7d30\u80de\u7684\u80fd\u529b\u3002\u4f9d\u5e79\u7d30\u80de\u7684\u5206\u5316\u6f5b\u80fd\u53ef\u5340\u5206\u70ba\uff1a<\/p>\n<p><span style=\"color: #800080;\">$$(1)$$ \u5168\u80fd\u5206\u5316\u6027\uff08totipotency\uff09\uff1a<\/span>\u751f\u7269\u9ad4\u4e2d\u55ae\u4e00\u500b\u7d30\u80de\u53ef\u5206\u88c2\u8207\u5206\u5316\u7522\u751f\u6240\u6709\u7d30\u80de\u7684\u80fd\u529b\uff0c\u4f8b\u5982\u5b62\u5b50\u548c\u53d7\u7cbe\u5375\uff08<a title=\"Zygote\" href=\"http:\/\/en.wikipedia.org\/wiki\/Zygote\">zygote<\/a>\uff09\u3002\u4eba\u985e\u5f9e\u7b2c\u4e00\u500b\u7d30\u80de\uff0d\u53d7\u7cbe\u5375\u5230\u7d04\u7b2c $$4$$ \u5929\uff0c\u6703\u5206\u88c2\u6210 $$8$$ \u500b\u7d30\u80de\u7684\u6851\u6939\u80da\uff08<a title=\"Morula\" href=\"http:\/\/en.wikipedia.org\/wiki\/Morula\">morula<\/a>\uff09\u6642\u671f\uff0c\u5f9e\u9019\u6642\u80da\u80ce\u5167\u5206\u96e2\u51fa\u7684\u7d30\u80de\u7a31\u70ba\u5168\u80fd\u6027\u5e79\u7d30\u80de\uff08totipotent stem cell\uff09\u3002<\/p>\n<p>\u5168\u80fd\u6027\u5e79\u7d30\u80de\u5177\u6709\u5206\u5316\u6210\u70ba\u9ad4\u5167\u6240\u6709\u7684\u7d44\u7e54\u548c\u80ce\u76e4\u7684\u80fd\u529b\uff0c\u6709\u6f5b\u529b\u53ef\u5206\u5316\u6210\u80da\u80ce\u7684\u4e09\u500b\u80da\u5c64\uff08three germ layers\uff09\uff0c\u5305\u62ec\u5167\u80da\u5c64\uff08endoderm\uff09\uff0d\u53ef\u767c\u80b2\u70ba\u6d88\u5316\u7ba1\u3001\u809d\u3001\u80f0\u548c\u80ba\u7b49\uff1b\u4e2d\u80da\u5c64\uff08mesoderm\uff09\uff0d\u53ef\u767c\u80b2\u70ba\u8840\u6db2\u3001\u808c\u8089\u3001\u9aa8\u9abc\u3001\u7d50\u7de0\u7d44\u7e54\u3001\u6ccc\u5c3f\u5668\u5b98\u548c\u751f\u6b96\u5668\u5b98\u7b49\uff1b\u5916\u80da\u5c64\uff08ectoderm\uff09\uff0d\u53ef\u767c\u80b2\u70ba\u8868\u76ae\u7d44\u7e54\u3001\u76ae\u819a\u3001\u7259\u9f52\u743a\u746f\u8cea\u3001\u773c\u775b\u6c34\u6676\u9ad4\u548c\u795e\u7d93\u7cfb\u7d71\u7b49\u3002\u5168\u80fd\u5206\u5316\u6027\u4e5f\u5c31\u662f\u5177\u6709\u53ef\u767c\u80b2\u6210\u5b8c\u6574\u500b\u9ad4\u7684\u6f5b\u80fd\uff0c\u76ee\u524d\u4eba\u985e\u5c0d\u6b64\u8907\u96dc\u7684\u6a5f\u8f49\u5c1a\u672a\u5b8c\u5168\u4e86\u89e3\u3002<\/p>\n<p><strong><span style=\"color: #800080;\">$$(2)$$ \u8d85\u591a\u80fd\u5206\u5316\u6027\uff08pluripotency\uff09\uff1a<\/span><\/strong>\u7d30\u80de\u53ef\u767c\u80b2\u70ba\u9ad4\u5167\u7684\u4efb\u4f55\u7d44\u7e54\u7684\u80fd\u529b\uff0c\u4f46\u4e26\u975e\u5168\u80fd\u800c\u6709\u90e8\u5206\u9650\u5236\u3002\u4ee5\u4eba\u985e\u70ba\u4f8b\uff0c\u53d7\u7cbe\u5f8c\u7d04\u7b2c $$4$$ \u5929\uff0c\u53d7\u7cbe\u5375\u6703\u5206\u88c2\u6210 $$16$$ \u500b\u7d30\u80de\u7684\u6851\u6939\u80da\u671f\uff0c\u7d04\u7b2c $$4$$\uff5e$$5$$ \u5929\u53ef\u767c\u80b2\u6210\u4e2d\u7a7a\u7684\u56ca\u80da\u671f\uff08<em>blastocyst stage<\/em>\uff09\u3002<\/p>\n<p>\u56ca\u80da\u4e3b\u8981\u7531\u4e09\u5c64\u69cb\u9020\u7d44\u6210\uff0c\u5176\u6700\u5916\u5c64\u662f\u6ecb\u990a\u5916\u80da\u5c64\uff0c\u5176\u7d30\u80de\u7a31\u70ba\u6ecb\u990a\u5916\u80da\u5c64\u7d30\u80de\uff08trophoblast cell\uff09\uff0c\u662f\u5f9e\u6851\u6939\u80da\u7684\u5916\u90e8\u7d30\u80de\u767c\u80b2\u5f62\u6210\uff0c\u5c07\u4f86\u6703\u767c\u80b2\u70ba\u80ce\u76e4\uff08placenta\uff09\uff1b\u56ca\u80da\u5167\u5c64\u662f\u7531\u5145\u6eff\u6db2\u9ad4\u7684\u4e2d\u7a7a\u56ca\u80da\u8154\uff08blastocoel\uff09\u548c\u5177\u6709 $$32$$\uff5e$$64$$\u00a0\u500b\u7d30\u80de\u7684\u5167\u7d30\u80de\u5718\uff08inner cell mass\uff0cICM\uff09\u6240\u69cb\u6210\u3002<\/p>\n<p>\u82e5\u7531\u6b64\u6642\u7684\u5167\u90e8\u7d30\u80de\u5718\u62bd\u53d6\u5206\u96e2\u51fa\u7684<em>\u7d30\u80de\uff0c\u7a31\u70ba<\/em>\u56ca\u80da\u80da\u80ce\u5e79\u7d30\u80de\uff08blastocyst embryonic stem cell\uff09\u3002\u56ca\u80da\u671f\u7684\u5167\u90e8\u7d30\u80de\u5718\u53ef\u5206\u5316\u6210\u80da\u80ce\u7684\u4e09\u500b\u80da\u5c64\u7684\u6240\u6709\u7d30\u80de\uff0c\u767c\u80b2\u6210\u80da\u80ce\u672c\u9ad4\u548c\u80da\u80ce\u5916\u7684\u819c\uff0c\u5982\u5375\u9ec3\u56ca\u819c\uff08yolk sac\uff09\u3001\u5c3f\u56ca\u819c\uff08allantois\uff09\u53ca\u7f8a\u819c\uff08amnion\uff09\u3002\u4f46\u662f\u56ca\u80da\u80da\u80ce\u5e79\u7d30\u80de\u4e26\u975e\u5168\u80fd\u5206\u5316\u6027\uff0c\u5b83\u96d6\u7136\u80fd\u767c\u80b2\u70ba\u9ad4\u5167\u7684\u4efb\u4f55\u7d44\u7e54\uff0c\u4f46\u4ecd\u6709\u90e8\u5206\u9650\u5236\u6027\uff0c\u4f8b\u5982\u7121\u6cd5\u767c\u80b2\u6210\u5b8c\u6574\u7684\u500b\u9ad4\u6216\u80ce\u76e4\uff0c\u5176\u5206\u5316\u80fd\u529b\u7a31\u70ba\u8d85\u591a\u80fd\u5206\u5316\u6027\u3002<\/p>\n<p>\u5177\u6709\u8d85\u591a\u80fd\u5206\u5316\u6027\u7684\u7d30\u80de\u9664\u4e86\u56ca\u80da\u671f\u7684\u80da\u80ce\u5e79\u7d30\u80de\uff08ES\uff09\uff0c\u76ee\u524d\u5df2\u77e5\u6709\u751f\u6b96\u5e79\u7d30\u80de\uff08embryonic germ cell\uff0cEG\uff09\u3001\u80da\u80ce\u764c\u7d30\u80de\uff08embryonic carcinoma cell\uff0cEC\uff09\u548c\u8a98\u5c0e\u5f0f\u8d85\u591a\u80fd\u5e79\u7d30\u80de\uff08iPS\uff09\u3002\u751f\u6b96\u5e79\u7d30\u80de\u662f\u5f9e\u53d7\u7cbe\u5f8c\u7d045~9\u9031\u80ce\u5152\u7684\u539f\u59cb\u751f\u6b96\u7d30\u80de\uff08primordal germ cell\uff09\u4e2d\u5206\u96e2\u51fa\u5f8c\uff0c\u5728\u8a66\u7ba1\u4e2d\u9ad4\u5916\u57f9\u990a\uff08in vitro\uff09\u6240\u589e\u751f\u7684\u7d30\u80de\uff0c\u7a31\u70ba\u751f\u6b96\u5e79\u7d30\u80de\uff08EG\uff09\uff0c\u662f\u6027\u817a\u7684\u524d\u9a45\u7d30\u80de\uff08precursor cell\uff09\u3002<\/p>\n<p>\u539f\u59cb\u751f\u6b96\u7d30\u80de\uff08PGCs\uff09\u662f\u767c\u80b2\u904e\u7a0b\u4e2d\uff0c\u914d\u5b50\u7684\u524d\u8eab\uff08precursor\uff09\u5728\u6027\u817a\u4ee5\u5916\u7684\u5730\u5340\u7a31\u4e4b\uff0c\u7576\u539f\u59cb\u751f\u6b96\u7d30\u80de\u9077\u79fb\u5230\u9054\u9069\u7576\u8655\u6703\u958b\u59cb\u767c\u80b2\u70ba\u539f\u59cb\u6027\u817a\uff0c\u7136\u5f8c\u767c\u80b2\u70ba\u6027\u817a\uff0c\u5375\u5de2\u6216\u777e\u4e38\uff0c\u518d\u7d93\u6e1b\u6578\u5206\u88c2\u5f8c\u7522\u751f\u914d\u5b50\uff0c\u7cbe\u5b50\u6216\u5375\u3002\u5728\u9ad4\u5916\uff08in vitro\uff09\u5be6\u9a57\u8b49\u5be6\u80da\u80ce\u5e79\u7d30\u80de\uff08ES\uff09\u548c\u751f\u6b96\u5e79\u7d30\u80de\uff08EG\uff09\u90fd\u5177\u6709\u8d85\u591a\u80fd\u5206\u5316\u6027\uff0c\u4f46\u751f\u7269\u9ad4\u5167\uff08in vivo\uff09\u53ea\u6709\u80da\u80ce\u5e79\u7d30\u80de\u53ef\u8868\u73fe\u8d85\u591a\u80fd\u5206\u5316\u6027\uff0c\u751f\u6b96\u5e79\u7d30\u80de\u5247\u7121\u6cd5\u3002<\/p>\n<p>\u9084\u6709\u80da\u80ce\u764c\u7d30\u80de\uff08EC\uff09\uff0c\u662f\u7531\u764c\u7d30\u80de\uff08teratocarcinoma\uff09\u6240\u5206\u96e2\u51fa\u4f86\u7684\uff0c\u5c6c\u65bc\u60e1\u6027\u7684\u4eba\u985e\u80da\u80ce\u5e79\u7d30\u80de\uff08hES\uff09\u3002\u4f46\u80da\u80ce\u764c\u7d30\u80de\u8207\u4e0a\u8ff0\u4e8c\u8005\u7684\u6700\u5927\u5dee\u7570\u662f\u5b83\u901a\u5e38\u662f\u975e\u6574\u500d\u9ad4\uff08aneuploid\uff09\uff0c\u6240\u8b02\u975e\u6574\u500d\u9ad4\u4e0d\u540c\u65bc\u591a\u500d\u9ad4\uff0c\u5176\u539f\u56e0\u53ef\u80fd\u662f\u4e00\u5c0d\u6216\u591a\u5c0d\u540c\u6e90\u67d3\u8272\u9ad4\u4e0d\u5206\u96e2\u7684\u7d50\u679c\uff0c\u9020\u6210\u67d3\u8272\u9ad4\u6578\u76ee\u7684\u7a81\u8b8a\uff0c\u589e\u52a0\u6216\u6e1b\u5c11\uff0c\u4e00\u689d\u6216\u5e7e\u689d\uff1b\u6216\u53ef\u80fd\u662f\u67d3\u8272\u9ad4\u7247\u6bb5<em>\u7f3a\u5931<\/em>\u6216<em>\u91cd\u8907<\/em>\u7b49\u3002<\/p>\n<p><strong><span style=\"color: #800080;\">$$(3)$$ \u591a\u80fd\u5206\u5316\u6027\uff08multipotency\uff09\uff1a<\/span><\/strong>\u5177\u6709\u591a\u80fd\u5206\u5316\u6027\u7684<a title=\"\u7956\u7d30\u80de\" href=\"http:\/\/translate.googleusercontent.com\/translate_c?depth=1&amp;hl=zh-TW&amp;prev=\/search%3Fq%3Dpluripotency%26biw%3D1280%26bih%3D620%26site%3Dwebhp&amp;rurl=translate.google.com.tw&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Progenitor_cell&amp;usg=ALkJrhiiJfD2Xz8y2Bq8wuR9WfPF-6RnmQ\">\u524d\u9a45\u7d30\u80de<\/a>\uff08\u539f\u59cb\u7d30\u80de\uff0cprogenitor cell\uff09\u4e3b\u8981\u5b58\u5728\u9aa8\u9ad3\u5167\uff0c\u6709\u57fa\u56e0\u6d3b\u5316\u7684\u6f5b\u80fd\uff0c\u56e0\u6b64\u53ef\u589e\u751f\u3001\u9077\u79fb\u4e26\u5206\u5316\u6210\u591a\u7a2e\u6210\u719f\u7d30\u80de\u985e\u578b\u7684\u80fd\u529b\uff0c\u4f46\u662f\u6709\u6240\u9650\u5236\u3002\u985e\u4f3c\u8d85\u591a\u80fd\u5206\u5316\u6027\u537b\u4e0d\u76f8\u540c\uff0c\u8d85\u591a\u80fd\u5206\u5316\u6027\u7684\u80da\u80ce\u5e79\u7d30\u80de\u53ef\u4ee5\u7121\u9650\u6b21\u8907\u88fd\u800c\u4e14\u5c1a\u672a\u5206\u5316\uff1b\u5177\u6709\u591a\u80fd\u5206\u5316\u6027\u7684\u524d\u9a45\u7d30\u80de\u50c5\u53ef\u6709\u9650\u6b21\u6578\u7684\u8907\u88fd\uff0c\u800c\u4e14\u5df2\u662f\u8f03\u5206\u5316\u7684\uff08specific\uff09\uff0c\u8f03\u63a5\u8fd1\u5f62\u6210\u76ee\u6a19\u7d30\u80de\u3002<\/p>\n<p>\u4f8b\u5982\u7531\u9aa8\u9ad3\u88fd\u9020\u53d6\u5f97\u7684\u9020\u8840\u5e79\u7d30\u80de\uff08hematopoietic <em>stem cells<\/em><em>\uff0c<\/em>HSCs\uff09\u5177\u6709\u591a\u80fd\u5206\u5316\u6027\uff0c\u53ef\u5206\u5316\u51fa\u9aa8\u9ad3\u5e79\u7d30\u80de\uff08myeloid stem cell\uff0cmyeloid progenitor\uff09\u548c\u6dcb\u5df4\u5e79\u7d30\u80de\uff08lymphoid stem cell\uff0clymphoid progenitor\uff09\uff0c\u5171\u53ef\u5206\u5316\u51fa\u81f3\u5c11\u5341\u4e00\u7a2e\u7684\u8840\u6db2\u7d30\u80de\uff0c\u4f46\u7121\u6cd5\u5206\u5316\u51fa\u5faa\u74b0\u7cfb\u7d71\u4ee5\u5916\u7684\u5176\u4ed6\u7d30\u80de\u5982\u795e\u7d93\u7d30\u80de\u6216\u808c\u8089\u7d30\u80de\u7b49\uff08\u5716\u56db\uff09\u3002<\/p>\n<p><strong><span style=\"color: #800080;\">$$(4)$$ \u5be1\u80fd\u5206\u5316\u6027\uff08oligopotency\uff09\uff1a<\/span><\/strong>\u5982\u9aa8\u9ad3\u5167\u7684<a title=\"\u7956\u7d30\u80de\" href=\"http:\/\/translate.googleusercontent.com\/translate_c?depth=1&amp;hl=zh-TW&amp;prev=\/search%3Fq%3Dpluripotency%26biw%3D1280%26bih%3D620%26site%3Dwebhp&amp;rurl=translate.google.com.tw&amp;sl=en&amp;u=http:\/\/en.wikipedia.org\/wiki\/Progenitor_cell&amp;usg=ALkJrhiiJfD2Xz8y2Bq8wuR9WfPF-6RnmQ\">\u524d\u9a45\u7d30\u80de<\/a>\u50c5\u5177\u6709\u5206\u5316\u51fa\u4e00\u4e9b\u985e\u578b\u7d30\u80de\u7684\u80fd\u529b\uff0c\u7a31\u70ba\u5be1\u80fd\u5206\u5316\u6027\uff0c\u63d0\u53d6\u51fa\u7684\u7d30\u80de\u7a31\u70ba\u5be1\u80fd\u5e79\u7d30\u80de\uff08oligopotent <em>stem cell<\/em>\uff09\uff0c\u4f8b\u5982\u6dcb\u5df4\u5e79\u7d30\u80de\u6216\u9aa8\u9ad3\u5e79\u7d30\u80de\u3002\u6dcb\u5df4\u5e79\u7d30\u80de\u53ef\u5206\u5316\u6dcb\u5df4\u6bcd\u7ec6\u80de\uff08lymphoblast\uff09\uff0c\u518d\u5206\u5316\u51fa B \u6dcb\u5df4\u7403\u3001T \u6dcb\u5df4\u7403\u548c\u5929\u7136\u6bba\u624b\u7d30\u80de\u7b49\uff0c\u4e0d\u540c\u7d30\u80de\u5404\u6709\u4e0d\u540c\u529f\u80fd\u3002<\/p>\n<p>\u9aa8\u9ad3\u5e79\u7d30\u80de\u53ef\u5206\u5316\u51fa\u7d05\u8840\u7403\u3001\u8840\u5c0f\u677f\u3001\u6210\u9ad3\u7d30\u80de\uff08myeloblast\uff09\u548c\u5167\u76ae\u524d\u9a45\u7d30\u80de\uff08endothelial progenitor cells\uff0cEPCs\uff09\uff0c\u6210\u9ad3\u7d30\u80de\u5206\u5316\u51fa\u4e0d\u540c\u767d\u8840\u7403\u5982\u5de8\u566c\u7d30\u80de\u3001\u55dc\u9e7c\u6027\u7403\u3001\u55dc\u4e2d\u6027\u7403\u3001\u548c\u55dc\u9178\u6027\u7403\u7b49\u3002\u5167\u76ae\u524d\u9a45\u7d30\u80de\u5247\u80fd\u91cd\u5efa\u8840\u7ba1\u5167\u76ae\u5c64\uff08re-endothelialization\uff09\u548c\u8840\u7ba1\u65b0\u751f\uff08neovascularization\uff09\u529f\u80fd\u3002<\/p>\n<p><strong><span style=\"color: #800080;\">$$(5)$$ \u55ae\u80fd\u5206\u5316\u6027\uff08unipotency\uff09\uff1a<\/span><\/strong>\u4e00\u500b\u5e79\u7d30\u80de\u5177\u6709\u5206\u5316\u6210\u53ea\u6709\u4e00\u500b\u7d30\u80de\u985e\u578b\u7684\u80fd\u529b\u7684\u6982\u5ff5\uff0c\u76ee\u524d\u5c1a\u672a\u6e05\u695a\u662f\u5426\u6709\u55ae\u80fd\u5206\u5316\u6027\u7684\u7d30\u80de\u5b58\u5728\uff0c\u5df2\u77e5\u809d\u6bcd\u7d30\u80de\uff08hepatoblast\uff09\u53ef\u5206\u5316\u51fa\u809d\u7d30\u80de\uff08<a title=\"Hepatocytes\" href=\"http:\/\/translate.googleusercontent.com\/translate_c?anno=2&amp;depth=1&amp;hl=zh-TW&amp;rurl=translate.google.com.tw&amp;sl=en&amp;tl=zh-TW&amp;u=http:\/\/en.wikipedia.org\/wiki\/Hepatocytes&amp;usg=ALkJrhhRbvZROrXxoVukfrOkYqlXCEfosA\">hepatocyte<\/a>\uff09\u548c\u69cb\u6210\u81bd\u7ba1\u4e0a\u76ae\u7684\u81bd\u7ba1\u7d30\u80de\uff08<a title=\"Cholangiocytes\" href=\"http:\/\/translate.googleusercontent.com\/translate_c?anno=2&amp;depth=1&amp;hl=zh-TW&amp;rurl=translate.google.com.tw&amp;sl=en&amp;tl=zh-TW&amp;u=http:\/\/en.wikipedia.org\/wiki\/Cholangiocytes&amp;usg=ALkJrhhaLE6-vzjs0XaNLvHK_-Qx3dQPxw\">cholangiocyte<\/a>\uff09\u4ecd\u662f\u96d9\u80fd\u5206\u5316\u6027\uff08bipotent\uff09\u3002<\/p>\n<div id=\"attachment_67201\" style=\"width: 660px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/05\/53372_p1.png\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-67201\" class=\"wp-image-67201\" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2014\/05\/53372_p1-1024x683.png\" alt=\"53372_p1\" width=\"650\" height=\"433\" srcset=\"http:\/\/localhost\/wp-content\/uploads\/2014\/05\/53372_p1-1024x683.png 1024w, http:\/\/localhost\/wp-content\/uploads\/2014\/05\/53372_p1-300x200.png 300w, http:\/\/localhost\/wp-content\/uploads\/2014\/05\/53372_p1.png 1082w\" sizes=\"auto, (max-width: 650px) 100vw, 650px\" \/><\/a><p id=\"caption-attachment-67201\" class=\"wp-caption-text\">\u5716\u56db \u5177\u6709\u591a\u80fd\u5206\u5316\u6027\uff08multipotency\uff09\u7684\u9020\u8840\u5e79\u7d30\u80de\uff08hematopoietic stem cells\uff0cHSCs\uff09 \u5716\u7247\u4f86\u6e90\uff1ahttp:\/\/en.wikipedia.org\/wiki\/File:Hematopoiesis_simple.svg<\/p><\/div>\n<p>\u53c3\u8003\u8cc7\u6599\uff1a<\/p>\n<ol>\n<li>\u674e\u7f8e\u8abc\uff082009\uff09\u3002\u4f4e\u6c27\u904b\u52d5\u5c0d\u9020\u8840\u524d\u9a45\u7d30\u80de\u53ca\u5faa\u74b0\u5167\u76ae\u524d\u9a45\u7d30\u80de\u518d\u5206\u4f48\u7684\u5f71\u97ff\u3002\u78a9\u58eb\u8ad6\u6587\u3002\u53f0\u5317\uff1a\u9577\u5e9a\u91ab\u5b78\u9662\u5fa9\u5065\u7cfb\u7814\u7a76\u6240\u3002<\/li>\n<li>\u80da\u80ce\u5e79\u7d30\u80de\u7814\u7a76\u662f\u5426\u6709\u7121\u7aae\u7684\u79d1\u5b78\u50f9\u503c\uff1f\u00a0 <a href=\"http:\/\/www.fsjh.ilc.edu.tw\/Subject\/Penguin\/other\/biotec\/es-egcell.htm\">http:\/\/www.fsjh.ilc.edu.tw\/Subject\/Penguin\/other\/biotec\/es-egcell.htm<\/a><\/li>\n<li>\u5e79\u7d30\u80de\u7684\u672a\u4f86\u00a0 <a href=\"http:\/\/www.nsc.gov.tw\/scitechvista\/zh-tw\/Articles\/C\/0\/1\/10\/1\/1700.htm\">http:\/\/www.nsc.gov.tw\/scitechvista\/zh-tw\/Articles\/C\/0\/1\/10\/1\/1700.htm<\/a><\/li>\n<li>Blood stem cells: the pioneers of stem cell research<br \/>\n<a href=\"http:\/\/www.eurostemcell.org\/factsheet\/blood-stem-cells-pioneers-stem-cell-research\">http:\/\/www.eurostemcell.org\/factsheet\/blood-stem-cells-pioneers-stem-cell-research<\/a><\/li>\n<li>Cell potency\u00a0 <a href=\"http:\/\/en.wikipedia.org\/wiki\/Cell_potency\">http:\/\/en.wikipedia.org\/wiki\/Cell_potency<\/a><\/li>\n<li>Stem cell\u00a0 <a href=\"http:\/\/en.wikipedia.org\/wiki\/Stem_cell\">http:\/\/en.wikipedia.org\/wiki\/Stem_cell<\/a><\/li>\n<\/ol>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u8d85\u591a\u80fd\u5206\u5316\u6027\uff08pluripotency\uff09\uff0d\u5206\u5316\u6f5b\u80fd -\u4e0b \u81fa\u4e2d\u5e02\u96d9\u5341\u570b\u4e2d\u81ea\u7136\u9818\u57df\u738b\u6dd1\u537f\u6559\u5e2b \u9023\u7d50\uff1a\u8d85\u591a\u80fd\u5206\u5316\u6027&hellip;<\/p>\n","protected":false},"author":50,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[110,4815,4839,4843],"tags":[6485,6487,6472,6482,6489,6481,6488,6484,6486,6483],"class_list":["post-53372","post","type-post","status-publish","format-standard","hentry","category-lifesciecne00","category-lifesciecne006","category-lifesciecne006-01","category-lifesciecne006-06","tag-multipotency","tag-oligopotency","tag-pluripotency","tag-totipotency","tag-unipotency","tag-6481","tag-6488","tag-6484","tag-6486","tag-6483","loop-entry","cat-110","cat-4815","cat-4839","cat-4843","no-thumbnail"],"views":15584,"_links":{"self":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/53372","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/users\/50"}],"replies":[{"embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/comments?post=53372"}],"version-history":[{"count":1,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/53372\/revisions"}],"predecessor-version":[{"id":87065,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/53372\/revisions\/87065"}],"wp:attachment":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/media?parent=53372"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/categories?post=53372"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/tags?post=53372"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}