{"id":3105,"date":"2009-08-01T13:51:22","date_gmt":"2009-08-01T05:51:22","guid":{"rendered":"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/?p=3105"},"modified":"2021-10-06T16:48:21","modified_gmt":"2021-10-06T08:48:21","slug":"%e9%85%b5%e7%b4%a0%e7%9a%84%e6%b4%bb%e6%80%a7%e9%83%a8%e4%bd%8d%ef%bc%88active-site-in-enzymes%ef%bc%89","status":"publish","type":"post","link":"http:\/\/localhost\/%e9%85%b5%e7%b4%a0%e7%9a%84%e6%b4%bb%e6%80%a7%e9%83%a8%e4%bd%8d%ef%bc%88active-site-in-enzymes%ef%bc%89\/","title":{"rendered":"\u9175\u7d20\u7684\u6d3b\u6027\u90e8\u4f4d\uff08Active Site in Enzymes\uff09"},"content":{"rendered":"

\u9175\u7d20\u7684\u6d3b\u6027\u90e8\u4f4d\uff08Active Site in Enzymes\uff09<\/span>
\n \u53f0\u5317\u5e02\u7acb\u7b2c\u4e00\u5973\u5b50\u9ad8\u7d1a\u4e2d\u5b78\u4e09\u5e74\u7d1a\u8a31\u4f73\u84c1\/\u53f0\u5317\u5e02\u7acb\u7b2c\u4e00\u5973\u5b50\u9ad8\u7d1a\u4e2d\u5b78\u5316\u5b78\u79d1\u5468\u82b3\u5983\u8001\u5e2b\u4fee\u6539\/\u570b\u7acb\u53f0\u7063\u5e2b\u7bc4\u5927\u5b78\u5316\u5b78\u7cfb\u8449\u540d\u5009\u6559\u6388\u8cac\u4efb\u7de8\u8f2f<\/span><\/strong>
\n\u9175\u7d20\u50ac\u5316\u5291\uff08Enzymes as catalysts\uff09
\n\u9175\u7d20\u4e3b\u8981\u662f\u7403\u72c0\u86cb\u767d\u8cea\uff08globular protein\uff09\uff0c\u5176\u86cb\u767d\u8cea\u7684\u4e09\u7d1a\u7d50\u69cb\u5c07\u5206\u5b50\u74b0\u7e5e\u6210\u7403\u72c0\u6216\u6709\u6642\u975e\u5e38\u6241\u5f62\u7684\u7403\u72c0\uff0c\u5176\u4ed6\u7a2e\u985e\u7684\u86cb\u767d\u8cea\uff08\u7e96\u7dad\u86cb\u767d\u8cea\uff0cfibrous proteins\uff09\u5247\u662f\u64c1\u6709\u7626\u9577\u7684\u7d50\u69cb\uff0c\u53ef\u4ee5\u5728\u808c\u8089\u548c\u982d\u9aee\u7b49\u7d44\u7e54\u4e0a\u627e\u5230\u3002
\n\u9019\u4e9b\u7403\u72c0\u86cb\u767d\u8cea\u53ef\u4ee5\u6210\u70ba\u5177\u6709\u6975\u5927\u6d3b\u6027\u7684\u50ac\u5316\u5291\uff08catalysts\uff09\uff0c\u4e00\u5206\u5b50\u7684\u50ac\u5316\u5291\u5927\u7d04\u6bcf\u79d2\u53ef\u5206\u89e3\u5341\u842c\u500b\u904e\u6c27\u5316\u6c2b\uff08hydrogen peroxide\uff09\u5206\u5b50\uff0c\u9019\u662f\u975e\u5e38\u9a5a\u4eba\u7684\u3002\u4e0b\u5716\u662f\u50ac\u5316\u5291\u7684\u6a21\u578b\uff0c\u5448\u73fe\u4e86\u5176\u7403\u72c0\u7684\u7d50\u69cb\uff0c\u4ea6\u6709\u9ede\u50cf\u4e00\u5718\u7dda\u7e8f\u7e5e\u5728\u4e00\u8d77\u3002<\/p>\n

\"\"<\/a><\/p>\n

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\u6d3b\u6027\u90e8\u4f4d<\/strong>\uff08active site\uff09<\/p>\n

\u6d3b\u6027\u90e8\u4f4d\u662f\u86cb\u767d\u8cea\u8868\u9762\u4e0a\u56e0\u9175\u7d20\u647a\u758a\u6210\u4e09\u7d1a\u7d50\u69cb\u7684\u65b9\u5f0f\u6240\u5f62\u6210\u7684\u88c2\u75d5\u6216\u51f9\u9677\u8655\uff0c\u4e00\u500b\u8207\u5176\u5206\u5b50\u5f62\u72c0\u5c0d\u61c9\u7684\u5438\u5f15\u57fa\uff08attractive groups<\/span>\uff09\u53ef\u4ee5\u5728\u6d3b\u6027\u90e8\u4f4d\u7684\u5730\u65b9\u8207\u5176\u5206\u5b50\u543b\u5408\uff0c\u5176\u9918\u5206\u5b50\u5247\u4e0d\u80fd\u548c\u5176\u4e0d\u76f8\u5c0d\u61c9\u7684\u5438\u5f15\u57fa\u5728\u6d3b\u6027\u90e8\u4f4d\u8655\u9023\u7d50\u3002\u4e00\u500b\u5e38\u7528\u7684\u985e\u6bd4\u662f\u5c07\u5206\u5b50\u6bd4\u55bb\u6210\u9470\u5319\uff0c\u5c07\u9175\u7d20\u6bd4\u55bb\u6210\u9396\uff0c\u6b63\u78ba\u7684\u9470\u5319\u624d\u80fd\u89e3\u958b\u76f8\u5c0d\u61c9\u7684\u9396\uff0c\u5982\u4e0b\u5716\u6240\u793a\u3002<\/p>\n

\"\"<\/a><\/p>\n

(\u64f7\u53d6\u65bchttp:\/\/www.chemguide.co.uk\/organicprops\/aminoacids\/enzymes.html#top<\/a>)<\/p>\n

\u5728\u5316\u5b78\u4e2d\uff0c\u6211\u5011\u5c07\u5373\u5c07\u9032\u884c\u53cd\u61c9\u7684\u5206\u5b50\u7a31\u4f5c\u53cd\u61c9\u7269\uff08reactant\uff09\uff0c\u800c\u5728\u751f\u7269\u5b78\u548c\u751f\u5316\u5b78\uff0c\u5728\u9175\u7d20\u53cd\u61c9\u4e2d\u7684\u53cd\u61c9\u7269\u5247\u88ab\u7a31\u4f5c\u57fa\u8cea\uff08substrate\uff09\u3002<\/p>\n

\u9175\u7d20\u662f\u4e00\u7a2e\u86cb\u767d\u8cea\u5206\u5b50\u2500\u80fa\u57fa\u9178\u5269\u9918\u7269\uff08residues\uff09\u7684\u9577\u93c8\uff0c\u5411\u5916\u7a81\u51fa\u65bc\u93c8\u7684\u80fa\u57fa\u9178\u652f\u93c8\u70ba\u5176\u5b98\u80fd\u57fa\uff08\u201dR\u201d groups\uff09\u3002\u6d3b\u6027\u90e8\u4f4d\u4e0a\u5178\u578b\u5730\u6392\u5217\u8457\u4e09\u500b\u5230\u5341\u4e8c\u500b\u9019\u7a2e\u5b98\u80fd\u57fa\uff0c\u4e0b\u5716\u986f\u793a\u4e86\u60f3\u50cf\u4e2d\u6d3b\u6027\u90e8\u4f4d\u7684\u69cb\u9020\u5716\u3002<\/p>\n

\"\"<\/a><\/p>\n

(\u64f7\u53d6\u65bchttp:\/\/www.chemguide.co.uk\/organicprops\/aminoacids\/enzymes.html#top<\/a>)<\/span><\/p>\n

\u9019\u4e9b\u5b98\u80fd\u57fa\u64c1\u6709\u4e00\u4e9b\u7279\u6027\u662f\u86cb\u767d\u8cea\u4e09\u7d1a\u69cb\u9020\u7684\u8d77\u56e0\uff0c\u4f8b\u5982\u5b83\u5011\u53ef\u80fd\u64c1\u6709\u53ef\u5f62\u6210\u6c2b\u9375\u3001\u78b3\u5316\u6c2b\u93c8\uff08hydrocarbon chains<\/span>\uff09\u6216\u53ef\u5f62\u6210\u51e1\u5f97\u74e6\u529b\uff08van der Waals forces<\/span>\uff09\u7684\u74b0\u72c0\u96e2\u5b50\u57fa\uff0c\u5982\uff1a-NH3+<\/sup><\/span>\u57fa\u3001-COO-<\/span>\u57fa\u6216-OH<\/span>\u57fa\u3002\u50cf\u4e0a\u9762\u6240\u63d0\u7684\u9019\u4e9b\u5b98\u80fd\u57fa\u5728\u80fd\u5920\u8abf\u6574\u5b98\u80fd\u57fa\u5230\u9069\u7576\u3001\u6b63\u78ba\u7684\u4f4d\u7f6e\u4e0a\u4ee5\u5c0d\u61c9\u9175\u7d20\u6642\uff0c\u5b83\u5011\u53ef\u4ee5\u5e6b\u52a9\u57fa\u8cea\u9023\u63a5\u5230\u6d3b\u6027\u90e8\u4f4d\u4e0a\u3002\u4e0b\u5716\u986f\u793a\u4e86\u5305\u542b\u5169\u500b\u96e2\u5b50\u9375\u548c\u4e00\u500b\u6c2b\u9375\u53ef\u80fd\u7684\u4ea4\u4e92\u4f5c\u7528\u3002<\/p>\n

\"\"<\/a><\/p>\n

(\u64f7\u53d6\u65bchttp:\/\/www.chemguide.co.uk\/organicprops\/aminoacids\/enzymes.html#top<\/a>)<\/span><\/p>\n

\u5b98\u80fd\u57fa\u4e0a\u793a\u6709+<\/span>\u6216–<\/span>\u7684\u7b26\u865f\u4ee3\u8868\u4e86\u96e2\u5b50\u9375\uff0c\u800c\u64c1\u6709\u201dH\u201d<\/span>\u8868\u793a\u7684\u9375\u4e0a\u5247\u4ee3\u8868\u4e86\u6c2b\u9375\u7684\u9023\u7d50\uff0c\u9664\u6b64\u4e4b\u5916\uff0c\u64c1\u6709\u5176\u4ed6\u7684\u5b98\u80fd\u57fa\u4ee5\u51e1\u5f97\u74e6\u529b\u9023\u7d50\u6d3b\u6027\u90e8\u4f4d\u548c\u57fa\u8cea\u4e5f\u662f\u6709\u53ef\u80fd\u7684\u3002\u5982\u679c\u5728\u6d3b\u6027\u90e8\u4f4d\u548c\u57fa\u8cea\u4e0a\u7684\u5b98\u80fd\u57fa\u4e0a\u6709\u4e86\u4e9b\u8a31\u7684\u6539\u8b8a\uff0c\u57fa\u8cea\u5c07\u4e0d\u80fd\u9023\u63a5\u3001\u7b26\u5408\u539f\u4f86\u7684\u9175\u7d20\u3002<\/p>\n

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\"\"<\/a><\/p>\n

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\u70ba\u4f55\u53cd\u61c9\u7269\u63a5\u4e0a\u9175\u7d20\u5c07\u589e\u52a0\u5176\u53cd\u61c9\u8f49\u63db\u6210\u7522\u7269\u901f\u7387\u7684\u539f\u56e0\u662f\u56e0\u70ba\u50ac\u5316\u5291\uff08\u5305\u542b\u9175\u7d20\u7b49\uff09\u53ef\u4ee5\u964d\u4f4e\u5176\u53cd\u61c9\u7684\u6d3b\u5316\u80fd\uff08activation energy<\/span>\uff09\uff0c\u5c07\u53cd\u61c9\u7269\u9023\u7d50\u5230\u6d3b\u6027\u90e8\u4f4d\u4e0a\u6703\u7522\u751f\u96fb\u5b50\u7684\u8df3\u52d5\uff08electron movements<\/span>\uff09\uff0c\u6700\u7d42\u5c07\u7834\u58de\u5176\u9593\u7684\u9375\u7d50\uff0c\u5947\u7279\u5730\u662f\u82e5\u60c5\u6cc1\u66f4\u70ba\u8907\u96dc\u5c07\u4f7f\u5176\u53cd\u61c9\u7684\u9032\u884c\u66f4\u52a0\u5bb9\u6613\u3002<\/p>\n

\u53c3\u8003\u8cc7\u6599<\/strong><\/p>\n

1. http:\/\/www.chemguide.co.uk\/organicprops \u2026 s.html#top<\/a>
\n2. http:\/\/terms.nict.gov.tw\/search1.php<\/a>
\n3. http:\/\/www.rcsb.org\/pdb\/home\/home.do<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

\u9175\u7d20\u7684\u6d3b\u6027\u90e8\u4f4d\uff08Active Site in Enzymes\uff09 \u53f0\u5317\u5e02\u7acb\u7b2c\u4e00\u5973\u5b50\u9ad8\u7d1a\u4e2d\u5b78\u4e09\u5e74\u7d1a\u8a31\u4f73\u84c1\/\u53f0\u5317\u5e02\u7acb…<\/p>\n","protected":false},"author":50,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[108,78,77],"tags":[1313,1247,1312],"class_list":["post-3105","post","type-post","status-publish","format-standard","hentry","category-chemistry00","category-chemistry08-01","category-chemistry08","tag-1313","tag-1247","tag-1312","avhec_catgroup-all","loop-entry","cat-108","cat-78","cat-77","no-thumbnail"],"views":6714,"_links":{"self":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/3105","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/users\/50"}],"replies":[{"embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/comments?post=3105"}],"version-history":[{"count":1,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/3105\/revisions"}],"predecessor-version":[{"id":90698,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/3105\/revisions\/90698"}],"wp:attachment":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/media?parent=3105"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/categories?post=3105"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/tags?post=3105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}