{"id":2511,"date":"2009-03-16T05:37:33","date_gmt":"2009-03-15T21:37:33","guid":{"rendered":"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/?p=2511"},"modified":"2021-10-06T16:50:28","modified_gmt":"2021-10-06T08:50:28","slug":"%e7%be%8e%e5%9c%8b%e7%ac%ac%e4%b8%80%e7%a8%ae%e6%a0%b8%e5%87%86%e4%b8%8a%e5%b7%bf%e7%9a%84%e4%ba%ba%e9%80%a0%e6%b2%b9%e8%84%82-olestrax","status":"publish","type":"post","link":"http:\/\/localhost\/%e7%be%8e%e5%9c%8b%e7%ac%ac%e4%b8%80%e7%a8%ae%e6%a0%b8%e5%87%86%e4%b8%8a%e5%b7%bf%e7%9a%84%e4%ba%ba%e9%80%a0%e6%b2%b9%e8%84%82-olestrax\/","title":{"rendered":"\u7f8e\u570b\u7b2c\u4e00\u7a2e\u6838\u51c6\u4e0a\u5dff\u7684\u4eba\u9020\u6cb9\u8102"},"content":{"rendered":"<div class=\"pf-content\"><p><strong><span style=\"color: #ff6600;\">\u7f8e\u570b\u7b2c\u4e00\u7a2e\u6838\u51c6\u4e0a\u5dff\u7684\u4eba\u9020\u6cb9\u8102 (Olestra)<\/span><br \/>\n<span style=\"color: #008000;\">\u9ad8\u96c4\u5e02\u9ad8\u96c4\u5973\u5b50\u9ad8\u7d1a\u4e2d\u5b78\u751f\u7269\u79d1\u8521\u4f69\u73ca\u5be6\u7fd2\u8001\u5e2b\/\u570b\u7acb\u81fa\u7063\u5e2b\u7bc4\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb\u674e\u51a0\u7fa4\u52a9\u7406\u6559\u6388\u8cac\u4efb\u7de8\u8f2f<\/span><\/strong><\/p>\n<p><span style=\"color: #000080;\"><strong>\u4e00\u3001\u524d\u8a00 :<\/strong><\/span><\/p>\n<p>Olestra\u662f\u4e00\u7a2e\u5408\u6210\u7684\u98df\u7528\u6cb9\u8102\uff0c\u7528Olestra\u88fd\u5099\u7684\u98df\u7269\uff0c\u7121\u8ad6\u662f\u714e\u3001\u7092\u3001\u716e\u3001\u70b8\u6216\u662f\u505a\u751f\u83dc\u6c99\u62c9\uff0c\u5176\u8272\u3001\u9999\u3001\u5473\u5e7e\u4e4e\u8207\u50b3\u7d71\u6cb9\u8102\u88fd\u5099\u7684\u98df\u7269\u4e00\u6a21\u4e00\u6a23\uff0c\u60df\u4e00\u4e0d\u4e00\u6a23\u4e4b\u8655\u5247\u662f\u6b64\u7a2e\u6cb9\u8102\u5728\u651d\u98df\u4e4b\u5f8c\uff0c\u4e0d\u6703\u88ab\u4eba\u9ad4\u7684\u6d88\u5316\u9053\u6240\u5438\u6536\uff0c\u56e0\u6b64\u5c31\u4eba\u9ad4\u7684\u5438\u6536\u89d2\u5ea6\u800c\u8a00\uff0cOlestra\u53ef\u8996\u4f5c\u662f&#8221;\u7121\u8102\u7684\u6cb9\u8102(fat-free fat)&#8221;\u3002\u56e0\u6b64\u4ee5Olestra\u70f9\u8abf\u7684\u98df\u7269\u8207\u50b3\u7d71\u6cb9\u8102\u70f9\u8abf\u98df\u7269\u4e4b\u9593\u7684\u6700\u5927\u5dee\u7570\u5c31\u5728\uff0c\u524d\u8005\u6c92\u6709\u6cb9\u8102\u800c\u4f86\u7684\u71b1\u91cf\uff0c\u6240\u4ee5\u53ef\u5c07\u6b64\u7a2e\u98df\u7269\u8996\u4f5c\u4f4e\u8102\u9910\u98df&#8221;low-fat diet&#8221;\u3002<!--more--><\/p>\n<p><span style=\"color: #000080;\"><strong>\u4e8c\u3001Olestra\u7684\u7d50\u69cb\uff1a<\/strong><\/span><\/p>\n<p>Olestra\u662f\u4e00\u500b\u8517\u7cd6\u5206\u5b50(sucrose)\u9023\u63a5\u516b\u500b\u5206\u5b50\u7684\u8102\u80aa\u9178\uff0c\u9019\u7a2e\u5408\u6210\u7684\u65b0\u5316\u5408\u7269\u5c31\u7a31\u70ba\u8517\u7cd6\u805a\u916f(sucrose polyester)\u3002 \u916f\u985e\u5728\u4eba\u9ad4\u5c0f\u8178\u4e2d\u5426\u88ab\u5206\u89e3\uff0c\u4e3b\u8981\u53d6\u6c7a\u65bc\u9175\u7d20(\u8102\u80aa\u9176,lipase)\u662f\u5426\u53ef\u9032\u5165\u916f\u985e\u7684\u5206\u5b50\u7d50\u69cb\u4e2d\uff0c\u4ee5\u4e09\u7518\u6cb9\u916f\u70ba\u4f8b\uff0clipase\u53ef\u8f15\u6613\u9032\u5165\u5176\u7d50\u69cb\u4e2d\u4e26\u5c07\u4e4b\u5206\u89e3\u6210\u8102\u80aa\u9178\u53ca\u7518\u6cb9(\u9187)\uff0c\u9019\u4e9b\u5206\u89e3\u5f8c\u7684\u6210\u5206\u7d93\u7531\u5c0f\u8178\u7684\u5fae\u8840\u7ba1\u5438\u6536\u9032\u5165\u4eba\u9ad4\u3002\u4f46\u662f\u8517\u7cd6\u805a\u916f\u5728\u9032\u5165\u5c0f\u8178\u4e4b\u5f8c\uff0c\u7531\u65bc\u805a\u916f\u7d50\u69cb\u8f03\u4e09\u7518\u6cb9\u916f\u70ba\u7dca\u5bc6\uff0c\u56e0\u6b64\u5c0f\u8178\u4e2d\u7684lipase\u4e26\u7121\u6cd5\u9032\u5165\u805a\u916f\u7d50\u69cb\u4e2d\u9032\u884c\u5207\u5272\uff0c\u56e0\u6b64\u8517\u7cd6\u805a\u916f\u5728\u672a\u88ab\u5c0f\u8178\u5438\u6536\u7684\u72c0\u614b\u4e0b\u7d93\u7531\u8178\u9053\u6392\u51fa\u9ad4\u5916\uff0c\u56e0\u70ba\u805a\u916f\u6c92\u6709\u88ab\u5438\u6536\uff0c\u81ea\u7136\u4e0d\u6703\u7522\u751f\u4efb\u4f55\u71b1\u91cf\u3002<\/p>\n<div id=\"attachment_9705\" style=\"width: 758px\" class=\"wp-caption alignnone\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2009\/03\/Olestrax1.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-9705\" class=\"wp-image-9705 \" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2009\/03\/Olestrax1.jpg\" alt=\"\" width=\"748\" height=\"191\" \/><\/a><p id=\"caption-attachment-9705\" class=\"wp-caption-text\">\u00a0 \u5716\u4e00\u3001\u8517\u7cd6\u805a\u916f\u7684\u805a\u5408\u65b9\u7a0b\u5f0f<\/p><\/div>\n<div id=\"attachment_9706\" style=\"width: 666px\" class=\"wp-caption alignnone\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2009\/03\/Olestrax2.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-9706\" class=\"wp-image-9706 size-full\" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2009\/03\/Olestrax2.jpg\" alt=\"\" width=\"656\" height=\"256\" \/><\/a><p id=\"caption-attachment-9706\" class=\"wp-caption-text\">\u5716\u4e8c\u3001\u8517\u7cd6\u805a\u916f(sucrose polyester)\u7684\u7d50\u69cb<\/p><\/div>\n<p>&nbsp;<\/p>\n<div id=\"attachment_9707\" style=\"width: 645px\" class=\"wp-caption alignnone\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2009\/03\/Olestrax3.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-9707\" class=\"wp-image-9707 \" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2009\/03\/Olestrax3.jpg\" alt=\"\" width=\"635\" height=\"285\" \/><\/a><p id=\"caption-attachment-9707\" class=\"wp-caption-text\">\u88681\u3001\u50b3\u7d71\u88fd\u6cd5\u548c\u6dfb\u52a0Olestra\u88fd\u6cd5\u71b1\u91cf\u7684\u6bd4\u8f03<\/p><\/div>\n<p><span style=\"color: #000080;\"><strong>\u4e09\u3001Olestra\u7684\u958b\u767c\u53f2\uff1a<\/strong><\/span><\/p>\n<p>(\u4e00)1959\u5e74\u7576\u6642\u5bf6\u9e7c\u516c\u53f8\u7684\u7814\u7a76\u4eba\u54e1\u5728\u7814\u7a76\u4eba\u9ad4\u5982\u4f55\u5206\u89e3\u8102\u80aa\uff0c\u5e0c\u671b\u958b\u767c\u51fa\u5b30\u5e7c\u5152\u53ef\u8fc5\u901f\u6d88\u5316\u7684\u8102\u80aa\u7522\u54c1\u3002<\/p>\n<p>(\u4e8c)\u7531\u5be6\u9a57\u5ba4\u52d5\u7269\u7684\u98fc\u990a\u8a66\u9a57\u767c\u73fe\uff0c\u4e00\u500b\u8102\u80aa\u9178\u8207\u4e00\u500b\u9187\u985e\u5316\u5408\u7269\u6240\u5f62\u6210\u7684\u916f\u985e\u5728\u52d5\u7269\u651d\u98df\u4e4b\u5f8c\uff0c\u53ef\u4ee5\u5f88\u5feb\u7684\u88ab\u5206\u89e3\u53ca\u5438\u6536\uff0c\u5169\u500b\u8102\u80aa\u9178\u7684\u916f\u66f4\u597d\uff0c\u4e09\u500b\u8102\u80aa\u9178\u7684\u916f\u985e\u5247\u6700\u5feb(\u4f8b\u5982\u4e09\u7518\u6cb9\u916f)\uff0c\u4f46\u662f\u4e00\u500b\u9187\u5206\u5b50\u4e0a\u9023\u63a5\u56db\u500b\u8102\u80aa\u9178\u7684\u916f\u985e\u7684\u5206\u89e3\u53ca\u5438\u6536\u80fd\u529b\u958b\u59cb\u4e0b\u964d\u3002<\/p>\n<p>(\u4e09)\u7814\u7a76\u4eba\u54e1\u767c\u73fe\u4e00\u500b\u8517\u7cd6\u5206\u5b50(sucrose)\u53ef\u9023\u63a5\u9ad8\u9054\u516b\u500b\u5206\u5b50\u7684\u8102\u80aa\u9178\uff0c\u9019\u7a2e\u5408\u6210\u7684\u65b0\u5316\u5408\u7269\u5c31\u7a31\u70ba\u8517\u7cd6\u805a\u916f(sucrose polyester)\u3002 (\u56db)\u5bf6\u9e7c\u516c\u53f8\u7684\u7814\u7a76\u4eba\u54e1\u57281971\u5e74\u63d0\u51fa\u5229\u7528\u8517\u7cd6\u805a\u916f\u4f5c\u70ba\u8102\u80aa\u66ff\u4ee3\u7269\u7684\u5c08\u5229\u7533\u8acb\u3002<\/p>\n<p>(\u4e94)1987\u5e74\u5bf6\u9e7c\u516c\u53f8\u6b63\u5f0f\u5411\u7f8e\u570b\u98df\u54c1\u8207\u85e5\u7269\u6aa2\u9a57\u5c40(FDA)\u63d0\u51fa\u4f7f\u7528\u8a31\u53ef\u3002<\/p>\n<p>(\u516d)FDA\u57281995\u5e74\u7684\u5341\u4e00\u6708\uff0c\u91dd\u5c0d\u5bf6\u9e7c\u516c\u53f8\u6240\u63d0\u51fa\u9577\u905415\u842c\u9801\u7684\u8a55\u4f30\u3001\u6e2c\u8a66\u5831\u544a\uff0c\u9080\u8acb\u4e8623\u4f4d\u4f86\u81ea\u5b78\u8853\u754c\u3001\u7522\u696d\u754c\u3001\u4ee5\u53ca\u6d88\u8cbb\u8005\u5354\u6703\u7684\u8a55\u8b70\u59d4\u54e1\uff0c\u9023\u7e8c\u958b\u4e86\u56db\u5929\u7684\u99ac\u62c9\u677e\u5f0f\u7684\u807d\u8b49\u6703\u3002\u5728\u6703\u8b70\u4e0a\uff0c\u5bf6\u9e7c\u516c\u53f8\u91dd\u5c0dOlestra\u4e00\u4e9b\u65e2\u6709\u7f3a\u9ede\u7684\u6539\u9032\u8fa6\u6cd5\u6216\u73fe\u6cc1\u63d0\u51fa\u975e\u5e38\u8a73\u76e1\u7684\u8aaa\u660e\u3002<\/p>\n<p>(\u4e03)\u76f8\u95dc\u7522\u54c1\u5728 1996\u5e74 1\u6708\u4e0a\u5e02\u3002<\/p>\n<p>(\u516b)FDA\u65bc1998\u5e74 6\u6708\u9032\u884c\u4e0a\u5e02\u5f8c\u7684\u518d\u8a55\u4f30\u3002<\/p>\n<p><span style=\"color: #000080;\"><strong>\u56db\u3001Olestra\u7684\u512a\u7f3a\u9ede\uff1a<\/strong><\/span><\/p>\n<div id=\"attachment_9708\" style=\"width: 605px\" class=\"wp-caption alignnone\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2009\/03\/Olestrax4.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-9708\" class=\"wp-image-9708 \" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2009\/03\/Olestrax4.jpg\" alt=\"\" width=\"595\" height=\"293\" \/><\/a><p id=\"caption-attachment-9708\" class=\"wp-caption-text\">\u88682\u3001Olestra\u7684\u512a\u7f3a\u9ede<\/p><\/div>\n<p>\u57fa\u672c\u4e0a\uff0cOlestra\u7684\u512a\u9ede\u4e5f\u5c31\u662f\u5bf6\u9e7c\u516c\u53f8\u5e0c\u671b\u958b\u767c\u7684\u5546\u6a5f\uff0c\u81f3\u65bc\u5176\u7f3a\u9ede\uff0c\u4e00\u985e\u662f\u6709\u95dc\u6cb9\u6eb6\u6027\u7dad\u751f\u7d20(A\u3001D\u3001E\u3001K)\u53ca\u985e\u80e1\u863f\u8514\u7d20\u7684\u5438\u9644\u554f\u984c\uff0c\u53e6\u4e00\u985e\u5247\u662fOlestra \u56e0\u70ba\u4e0d\u70ba\u4eba\u9ad4\u5438\u6536\u6240\u9020\u6210\u7684\u6d88\u5316(\u6392\u6d29)\u9053\u4e2d\u7cde\u4fbf\u9b06\u6563\u3001\u53ca\u809b\u6f0f\u73fe\u8c61\u3002\u81f3\u65bc\u8f15\u5fae\u7684\u98df\u5f8c\u611f\uff0c\u7531\u65bc\u4fc2\u7522\u54c1\u7684\u54c1\u8cea\u7279\u8272\uff0c\u6bd4\u8f03\u6c92\u6709\u592a\u591a\u7684\u722d\u8b70\u3002 \u6709\u95dcOlestra\u5438\u9644\u6cb9\u6eb6\u6027\u7dad\u751f\u7d20(A\u3001D\u3001E\u3001K)\u4e00\u4e8b\uff0c\u5bf6\u9e7c\u516c\u53f8\u7684\u89e3\u6c7a\u65b9\u6cd5\u5f88\u7c21\u55ae\uff0c\u5373\u5728\u73fe\u4eca\u7684Olestra\u914d\u65b9\u4e2d\u6dfb\u52a0\u904e\u91cf\u4e4b\u7dad\u751f\u7d20A\u3001D\u3001E\u3001K\uff0c\u4f7fOlestra\u7d50\u69cb\u4e2d\u5438\u6536\u9019\u4e9b\u7dad\u751f\u7d20\u7684\u7a7a\u9699\u90fd\u88ab\u586b\u6eff, \u56e0\u6b64\u5c31\u4e0d\u6703\u5728\u651d\u98df\u542bOleatra\u7684\u98df\u7269\u4e4b\u5f8c, 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\u5728\u98df\u5f8c\u6709\u7cde\u4fbf\u9b06\u6563\u3001\u4fbf\u6025\uff0c\u751a\u81f3\u809b\u6f0f(annal leakage)\u7684\u554f\u984c\uff0c\u5bf6\u9e7c\u516c\u53f8\u7684\u4e3b\u8981\u89e3\u91cb\u8b49\u64da\u662f\u4e00\u4efd\u4f86\u81ea3,357\u4f4d\u7d93\u5e38\u651d\u98df\u70b8\u99ac\u9234\u85f7\u7247\u7684\u6d88\u8cbb\u8005(\u5305\u62ec\u7537\u3001\u5973\u53ca\u5b69\u7ae5) \u8a55\u4f30\u5831\u544a\uff0c\u7d50\u679c\u5c0d\u7167\u7d44\u8207\u5be6\u9a57\u7d44\u4e4b\u9593\u5728\u4e0a\u8ff0\u73fe\u8c61\u4e4b\u5dee\u7570\u4e26\u4e0d\u986f\u8457\uff0c\u807d\u8b49\u6703\u8a0e\u8ad6\u81f3\u6b64\uff0c\u4f3c\u4e4e\u7121\u6cd5\u986f\u793a\u4ee5Olestra\u6cb9\u70b8\u7684\u99ac\u9234\u85f7\u7247\u6703\u5c0d\u6d88\u8cbb\u8005\u7522\u751f 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