{"id":22377,"date":"2009-07-09T22:45:39","date_gmt":"2009-07-09T14:45:39","guid":{"rendered":"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/?p=22377"},"modified":"2021-10-06T16:48:48","modified_gmt":"2021-10-06T08:48:48","slug":"%e7%94%9f%e7%89%a9%e6%a8%99%e8%a8%98biomarker%e6%98%af%e6%8a%97%e7%99%8c%e4%bb%99%e4%b8%b9anticancer-drug%ef%bc%9f","status":"publish","type":"post","link":"http:\/\/localhost\/%e7%94%9f%e7%89%a9%e6%a8%99%e8%a8%98biomarker%e6%98%af%e6%8a%97%e7%99%8c%e4%bb%99%e4%b8%b9anticancer-drug%ef%bc%9f\/","title":{"rendered":"\u751f\u7269\u6a19\u8a18(Biomarker)\u662f\u6297\u764c\u4ed9\u4e39(Anticancer Drug)\uff1f"},"content":{"rendered":"

<\/a>\u751f\u7269\u6a19\u8a18(Biomarker)\u662f\u6297\u764c\u4ed9\u4e39(Anticancer Drug)\uff1f<\/span>
\n\u77e5\u8b58\u901a\u8a0a\u8a55\u8ad6\u7b2c60\u671f<\/span><\/strong><\/p>\n

\u900f\u904e\u57fa\u56e0\u6aa2\u6e2c\u767c\u73fe\u764c\u75c7\u662f\u53ef\u884c\u7684\u3002\u4f46\u662f\u9762\u5c0d\u591a\u5982\u725b\u6bdb\u7684\u5404\u7a2e\u751f\u7269\u6a19\u8a18\uff0c\u624b\u4e0a\u6c92\u6709\u8db3\u5920\u7814\u7a76\u7d93\u8cbb\u7684\u7814\u7a76\u4eba\u54e1\uff0c\u8981\u628a\u751f\u7269\u6a19\u8a18\u5206\u6790\u6280\u8853\u5e36\u9032\u5e02\u5834\u6210\u70ba\u75be\u75c5\u8a3a\u65b7\u7684\u4e00\u74b0\uff0c\u5be6\u5728\u56f0\u96e3\u3002<\/strong><\/p>\n

<\/p>\n

\u57fa\u56e0\u9ad4\u91ab\u5b78\u4e0d\u65b7\u9032\u6b65\uff0c\u53ca\u6642\u767c\u73fe\u4e26\u4e14\u7cbe\u78ba\u638c\u63a7\u764c\u75c7\u7684\u65e9\u671f\u5fb5\u5146\u4e0d\u518d\u9059\u4e0d\u53ef\u53ca\u3002\u7814\u7a76\u300c\u5206\u5b50\u751f\u7269\u6a19\u8a18\u300d(molecular biomarker)\uff0c\u53ef\u4ee5\u5e6b\u52a9\u6211\u5011\u767c\u73fe\u75be\u75c5\u7684\u521d\u671f\u75c7\u5019\uff0c\u4e5f\u53ef\u5373\u6642\u9032\u884c\u6709\u6548\u7684\u6cbb\u7642\u3002\u7136\u800c\uff0c\u9019\u500b\u5922\u60f3\u81f3\u4eca\u4ecd\u672a\u5be6\u73fe\u3002<\/p>\n

\u5168\u4e16\u754c\u7684\u5be6\u9a57\u5ba4\u90fd\u5728\u7a4d\u6975\u5c0b\u627e\u53ef\u7528\u4f86\u5075\u6e2c\u75be\u75c5\u7684\u751f\u7269\u6a19\u8a18\u3002\u4f46\u662f\u8981\u628a\u9019\u7a2e\u751f\u7269\u6a19\u8a18\u77e5\u8b58\u767c\u5c55\u5230\u80fd\u5920\u7528\u65bc\u75be\u75c5\u8a3a\u65b7\uff0c\u9084\u6709\u4e00\u6bb5\u9577\u8def\u8981\u8d70\u3002\u7f8e\u570b\u653f\u5e9c\u7684\u4e3b\u7ba1\u6a5f\u95dc\u76ee\u524d\u9084\u6c92\u6709\u6279\u51c6\u4efb\u4f55\u4e00\u9805\u7528\u65bc\u65e9\u671f\u5075\u6e2c\u75be\u75c5\u7684\u8a3a\u65b7\u8a66\u9a57\u6cd5\u3002<\/p>\n

\"\"<\/a>

\u5e15\u65af\u91ab\u5e2b\uff08Harvey Pass\uff09\u8aaa\uff0c\u751f\u7269\u6a19\u8a18\u6700\u91cd\u8981\u7684\u529f\u80fd\uff0c\u61c9\u8a72\u8981\u80fd\u6307\u660e\u61c9\u7576\u63a1\u884c\u7684\u6cbb\u7642\u65b9\u6cd5\u6216\u75be\u75c5\u7684\u75c5\u7406\u72c0\u6cc1\u3002<\/p><\/div>\n

\u91ab\u85e5\u7522\u696d\u89c0\u5bdf\u5bb6\u8aaa\uff0c\u8981\u78ba\u5b9a\u67d0\u7a2e\u751f\u7269\u6a19\u8a18\u662f\u5426\u53ef\u4ee5\u5e6b\u52a9\u6211\u5011\u5075\u6e2c\u75be\u75c5\uff0c\u5341\u5206\u56f0\u96e3\uff0c\u6c92\u6709\u4eba\u80fd\u4fdd\u8b49\u9019\u4e9b\u751f\u7269\u6a19\u8a18\u6703\u8b8a\u6210\u80fd\u5920\u884c\u92b7\u4e0a\u5e02\u7684\u75be\u75c5\u6aa2\u6e2c\u6280\u8853\u3002\u6b64\u5916\uff0c\u9084\u5728\u5be6\u9a57\u968e\u6bb5\u7684\u751f\u7269\u6a19\u8a18\u7a2e\u985e\u7e41\u591a\uff0c\u8981\u9078\u51fa\u4e00\u500b\u6700\u6709\u767c\u5c55\u6f5b\u529b\u7684\u6a19\u8a18\uff0c\u4e5f\u4e0d\u5bb9\u6613\u3002<\/p>\n

\u91ab\u5e2b\u90fd\u5e0c\u671b\u9019\u7a2e\u751f\u7269\u6a19\u8a18\u6aa2\u6e2c\u80fd\u5920\u5e6b\u52a9\u4ed6\u5011\u627e\u5230\u5c0d\u7279\u5b9a\u75c5\u60a3\u6709\u6548\u7684\u7642\u7a0b\u3002\u554f\u984c\u5728\u65bc\uff0c\u7576\u9019\u4e9b\u751f\u7269\u6a19\u8a18\u53ea\u80fd\u7528\u65bc\u75c5\u60c5\u8a3a\u65b7\u537b\u7121\u6cd5\u660e\u78ba\u6307\u51fa\u6cbb\u7642\u65b9\u6cd5\u6642\uff0c\u91ab\u5e2b\u662f\u5426\u9858\u610f\u63a1\u7528\u3002<\/p>\n

\u7f8e\u570b\u7d10\u7d04\u5927\u5b78\u91ab\u5b78\u4e2d\u5fc3\u5c08\u9580\u7814\u7a76\u9593\u76ae\u764c\uff08mesothelioma\uff0c\u80f8\u8179\u8154\u5167\u896f\u7d44\u7e54\u7684\u60e1\u6027\u816b\u7624\uff09\u751f\u7269\u6a19\u8a18\u7684\u91ab\u5e2b\u5e15\u65af\uff08Harvey Pass\uff09\u8aaa\uff0c\u751f\u7269\u6a19\u8a18\u6700\u91cd\u8981\u7684\u529f\u80fd\uff0c\u61c9\u8a72\u8981\u80fd\u6307\u660e\u61c9\u7576\u63a1\u884c\u7684\u6cbb\u7642\u65b9\u6cd5\u6216\u75be\u75c5\u7684\u75c5\u7406\u72c0\u6cc1\u3002<\/p>\n

\u4e03\u5e74\u524d\uff0c\u7f8e\u570b\u570b\u5bb6\u764c\u75c7\u7814\u7a76\u6240\u6210\u7acb\u4e86\u300c\u65e9\u671f\u5075\u6e2c\u7814\u7a76\u7db2\u300d\uff08EDRN\uff09\uff0c\u5e0c\u671b\u85c9\u6b64\u78ba\u8a8d\u751f\u7269\u6a19\u8a18\u6280\u8853\u7684\u53ef\u9760\u5ea6\uff0c\u5efa\u7acb\u4e00\u5957\u6aa2\u6e2c\u8207\u9a57\u8b49\u751f\u7269\u6a19\u8a18\u662f\u5426\u6709\u6548\u7684\u6d41\u7a0b\u67b6\u69cb\u3002\u9019\u500b\u5de5\u7a0b\u76f8\u7576\u6d69\u5927\uff0c\u56e0\u70ba\u75be\u75c5\u8a3a\u65b7\u6aa2\u6e2c\u901a\u5e38\u9700\u8981\u540c\u6642\u904b\u7528\u597d\u5e7e\u7a2e\u4e0d\u540c\u7684\u751f\u7269\u6a19\u8a18\uff0c\u624d\u80fd\u78ba\u4fdd\u6aa2\u6e2c\u7d50\u679c\u5728\u7d71\u8a08\u4e0a\u662f\u6709\u986f\u8457\u610f\u7fa9\u3002<\/p>\n

\u6e2c\u8a66\u9032\u884c\u4e2d<\/strong><\/p>\n

EDRN\u9019\u500b\u7db2\u8def\u63d0\u51fa\u4e00\u500b\u5982\u4f55\u8a55\u5224\u751f\u7269\u6a19\u8a18\u662f\u5426\u6709\u6548\u7684\u8349\u6848\uff0c\u4e5f\u6307\u51fa\u4e86\u5404\u7a2e\u6709\u95dc\u5c64\u9762\u3002EDRN\u5728\u6210\u5343\u4e0a\u842c\u7a2e\u6f5b\u5728\u751f\u7269\u6a19\u8a18\u4e2d\u9078\u51fa\u4e86\u4e00\u767e\u5eff\u7a2e\uff0c\u9019\u4e9b\u751f\u7269\u6a19\u8a18\u4e5f\u5404\u5728\u4e0d\u540c\u7684\u7814\u767c\u968e\u6bb5\u3002<\/p>\n

\u9019\u4e00\u767e\u5eff\u7a2e\u751f\u7269\u6a19\u8a18\uff0c\u662f\u9593\u76ae\u764c\u3001\u809d\u764c\u3001\u8180\u80f1\u764c\u3001\u651d\u8b77\u817a\u764c\u8207\u80ba\u764c\u9019\u4e94\u7a2e\u764c\u75c7\u7684\u751f\u7269\u6a19\u8a18\uff0c\u6709\u7684\u4ecd\u5728\u7814\u767c\u7684\u7b2c\u4e09\u968e\u6bb5\uff0c\u6709\u7684\u5df2\u7d93\u9032\u5165\u6700\u5f8c\u968e\u6bb5\uff0c\u4e26\u4e14\u900f\u904e\u5927\u898f\u6a21\u7684\u4eba\u9ad4\u8a66\u9a57\u77ad\u89e3\u5176\u5075\u6e2c\u75be\u75c5\u7684\u6548\u679c\u5982\u4f55\u3002<\/p>\n

\u7f8e\u570b\u99ac\u91cc\u862d\u5dde\u751f\u7269\u79d1\u6280\u516c\u53f8Cangen Biotechnologies\u4e5f\u53c3\u8207\u4e86EDRN\u8a08\u756b\uff0c\u4ed6\u5011\u5fd7\u5728\u6210\u70ba\u7b2c\u4e00\u500b\u628aDNA\u70ba\u57fa\u790e\u7684\u8180\u80f1\u764c\u65e9\u671f\u5075\u6e2c\u6280\u8853\u63a8\u4e0a\u5e02\u5834\u7684\u516c\u53f8\u3002\u8a72\u516c\u53f8\u8868\u793a\uff0c\u4ed6\u5011\u5c0d\u81ea\u5df1\u7814\u767c\u3001\u4ee5\u5341\u4e94\u500bDNA\u7247\u6bb5\u7d44\u6210\u7684\u6aa2\u9a57\u5de5\u5177\u5f88\u6709\u4fe1\u5fc3\uff0c\u9019\u7a2e\u6aa2\u9a57\u5de5\u5177\u53ef\u4ee5\u6bd4\u5176\u4ed6\u8a3a\u65b7\u65b9\u5f0f\u66f4\u65e9\u767c\u73fe\u816b\u7624\u3002<\/p>\n

\u4e0d\u904e\uff0c\u96d6\u7136\u91ab\u5e2b\u53ef\u4ee5\u7528\u9019\u7a2e\u5de5\u5177\u66f4\u65e9\u767c\u73fe\u816b\u7624\uff0c\u5927\u90e8\u5206\u7684\u8180\u80f1\u764c\u60a3\u8005\u9084\u662f\u5f97\u7d93\u6b77\u624b\u8853\u3002\u63db\u8a00\u4e4b\uff0c\u9019\u7a2e\u65b0\u7684\u6aa2\u9a57\u5de5\u5177\u5c0d\u65bc\u8180\u80f1\u764c\u75c5\u60a3\u7684\u5b58\u6d3b\u7387\u53ea\u6709\u8f15\u5fae\u5f71\u97ff\u3002<\/p>\n

Cangen\u516c\u53f8\u7814\u7a76\u90e8\u9580\u4e3b\u7ba1\u827e\u6b4c\u6ce2\uff08Eddy Agbo\uff09\u8aaa\uff0c\u900f\u904e\u751f\u7269\u6a19\u8a18\u627e\u51fa\u53ef\u4ee5\u6cbb\u7642\u521d\u671f\u816b\u7624\u7684\u65b0\u85e5\u7269\u7642\u6cd5\uff0c\u662f\u4ed6\u5011\u672a\u4f86\u7684\u6311\u6230\u3002\u7136\u800c\uff0c\u7531\u65bc\u9019\u7a2e\u65b0\u5f0f\u85e5\u7269\u7642\u6cd5\u9084\u6c92\u554f\u4e16\uff0c\u7f8e\u570b\u7684\u91ab\u5e2b\u8207\u652f\u4ed8\u91ab\u7642\u7167\u8b77\u6a5f\u69cb\u8cbb\u7528\u7684\u4fdd\u96aa\u516c\u53f8\uff0c\u5c0d\u751f\u7269\u6a19\u8a18\u7684\u8208\u8da3\u6703\u5f88\u6709\u9650\u3002<\/p>\n

\u88fd\u85e5\u7522\u696d\u8cc7\u6e90\u8c50\u5bcc\uff0c\u4e5f\u8a31\u80fd\u4f7f\u4e3b\u7ba1\u6a5f\u95dc\u6279\u51c6\u751f\u7269\u6a19\u8a18\u6aa2\u6e2c\u6280\u8853\u3002\u4e0d\u904e\uff0c\u85e5\u5ee0\u6bd4\u8f03\u95dc\u5fc3\u7684\uff0c\u662f\u5982\u4f55\u900f\u904e\u751f\u7269\u6a19\u8a18\u77ad\u89e3\u60a3\u8005\u9069\u4e0d\u9069\u5408\u4f7f\u7528\u67d0\u7a2e\u85e5\u7269\uff0c\u85e5\u5ee0\u5c0d\u65e9\u671f\u5075\u6e2c\u8208\u8da3\u7f3a\u7f3a\u3002<\/p>\n

\u52a0\u5ddeGenentech\u516c\u53f8\u7814\u767c\u51fa\u6297\u4e73\u764c\u85e5\u7269Herceptin\uff0c\u662f\u500b\u6210\u529f\u6848\u4f8b\u3002Herceptin\u65e8\u5728\u6cbb\u7642\u90a3\u4e9b\u9ad4\u5167\u904e\u5ea6\u8868\u73fe\u67d0\u7a2e\u53d7\u9ad4\u7684\u4e73\u764c\u60a3\u8005\u3002\u5149\u662f\u53bb\u5e74\uff0cHerceptin\u5c31\u8ce3\u4e86\u5341\u4e09\u5104\u7f8e\u5143\u3002<\/p>\n

\"\"<\/a>

microRNAs<\/p><\/div>\n

\u897f\u96c5\u5716\u798f\u745e\u5fb7\u8d6b\u91d1\u68ee\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\u5206\u5b50\u751f\u7269\u5b78\u5bb6\u54c8\u5357\u8a31\uff08Sam Hanash\uff09\u8aaa\uff0c\u5927\u5bb6\u90fd\u5e0c\u671b\u770b\u5230\u751f\u7269\u6a19\u8a18\u6280\u8853\u51fa\u73fe\u6232\u5287\u6027\u7684\u6210\u529f\u3002\u54c8\u5357\u8a31\u8aaa\uff0c\u74f6\u9838\u4e0d\u5728\u65bc\u5be6\u9a57\u5ba4\u88e1\u7684\u79d1\u5b78\u662f\u5426\u5148\u9032\uff0c\u800c\u662f\u7814\u7a76\u4eba\u54e1\u8981\u5982\u4f55\u5728\u90a3\u9ebc\u591a\u7a2e\u57fa\u56e0\u3001\u86cb\u767d\u8cea\u8207\u5faeRNA\uff08microRNAs\uff09\u4e2d\u53bb\u856a\u5b58\u83c1\uff0c\u627e\u51fa\u81e8\u5e8a\u4e0a\u6709\u5be6\u7528\u50f9\u503c\u7684\u751f\u7269\u6a19\u8a18\u3002\u4ed6\u8a8d\u70ba\uff0c\u76ee\u524d\u7684\u72c0\u6cc1\u5c31\u50cf\u662f\u7f8e\u570b\u897f\u90e8\u62d3\u8352\u6642\u4ee3\uff0c\u6bcf\u500b\u4eba\u90fd\u80fd\u5ba3\u793a\u64c1\u6709\u4e00\u7247\u571f\u5730\uff0c\u6bcf\u500b\u5b78\u8005\u4e5f\u90fd\u80fd\u5ba3\u7a31\u767c\u73fe\u67d0\u7a2e\u751f\u7269\u6a19\u8a18\u3002<\/p>\n

\u7acb\u4e0b\u6a19\u7aff<\/strong><\/p>\n

EDRN\u8cbb\u4e86\u4e00\u756a\u529f\u592b\u5c0b\u627e\u6700\u6709\u6f5b\u529b\u7684\u751f\u7269\u6a19\u8a18\uff0c\u597d\u8b93\u9019\u4e9b\u751f\u7269\u6a19\u8a18\u9032\u5165\u81e8\u5e8a\u8a66\u9a57\u968e\u6bb5\u3002EDRN\u5df2\u80fd\u63d0\u4f9b\u7528\u65bc\u7814\u7a76\u80ba\u764c\u3001\u4e73\u764c\u3001\u5375\u5de2\u764c\u3001\u651d\u8b77\u817a\u764c\u548c\u7d50\u8178\u764c\u7b49\u764c\u75c7\u751f\u7269\u6a19\u8a18\u7684\u764c\u5316\u7d30\u80de\u7d44\u7e54\u3001\u8840\u6e05\u8207\u8840\u6db2\u6a23\u672c\u3002\u79d1\u5b78\u5bb6\u53ef\u4ee5\u7528\u9019\u4e9b\u6750\u6599\u521d\u6b65\u6aa2\u9a57\u751f\u7269\u6a19\u8a18\u7684\u53ef\u9760\u7a0b\u5ea6\u3002<\/p>\n

EDRN\u4e5f\u5efa\u7acb\u4e86\u9a57\u8b49\u751f\u7269\u6a19\u8a18\u6e2c\u8a66\u6548\u679c\u7684\u54c1\u7ba1\u6a19\u6e96\uff0c\u6709\u4e00\u6574\u5957\u5448\u73fe\u8cc7\u6599\u7684\u6a19\u6e96\u7cfb\u7d71\u3002EDRN\u9084\u8207\u7f8e\u570b\u570b\u5bb6\u764c\u75c7\u7814\u7a76\u6240\u7684\u5176\u4ed6\u5718\u968a\u8457\u624b\u5efa\u7acb\u4e00\u500b\u5927\u898f\u6a21\u7684\u4eba\u9ad4\u751f\u7269\u6a23\u672c\u5132\u5b58\u5eab\uff08human biosample collection\uff09\u3002<\/p>\n

\u5c08\u5bb6\u8a8d\u70ba\uff0c\u9019\u4e9b\u6b65\u9a5f\u78ba\u5be6\u6709\u5176\u5fc5\u8981\uff0c\u4f46\u662f\u9019\u4e9b\u4f5c\u6cd5\u4e0d\u4e00\u5b9a\u80fd\u628a\u751f\u7269\u6a19\u8a18\u6e2c\u8a66\u5e36\u5230\u5e02\u5834\u4e0a\u3002\u5728\u9ebb\u5dde\u5e03\u6d1b\u5fb7\u7814\u7a76\u6240\uff08Broad Institute\uff09\u7814\u7a76\u86cb\u767d\u8cea\u9ad4\u7684\u5409\u7acb\u7279\uff08Mike Gillette\uff09\u8aaa\uff0cEDRN\u63d0\u4f9b\u7684\u8cc7\u6e90\u96d6\u7136\u5f88\u6709\u50f9\u503c\uff0c\u537b\u4e0d\u5b8c\u6574\u3002\u5b78\u8005\u5fc5\u9808\u5c0d\u66f4\u5ee3\u5927\u7684\u75c5\u60a3\u4eba\u53e3\u9032\u884c\u5927\u898f\u6a21\u7684\u81e8\u5e8a\u8a66\u9a57\uff0c\u5426\u5247\u7121\u6cd5\u9032\u4e00\u6b65\u9a57\u8b49\u751f\u7269\u6a19\u8a18\u5075\u6e2c\u75be\u75c5\u7684\u6548\u679c\u3002\u9019\u500b\u5de5\u7a0b\u975e\u5e38\u6602\u8cb4\uff0c\u696d\u754c\u4e5f\u6c92\u6709\u592a\u5927\u8208\u8da3\u3002<\/p>\n

\u4eca\u5e74\u4e03\u6708\uff0c\u7f8e\u570b\u98df\u54c1\u85e5\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u91dd\u5c0d\u696d\u754c\u95dc\u5fc3\u7684\u751f\u7269\u6a19\u8a18\u6280\u8853\u5be9\u6838\u904e\u7a0b\u505a\u51fa\u8aaa\u660e\uff0c\u4e26\u767c\u8868\u4e86\u8349\u64ec\u7684\u6e96\u5247\uff0c\u7528\u4ee5\u898f\u7bc4\u4f7f\u7528\u591a\u7a2e\u751f\u7269\u6a19\u8a18\u7684\u6e2c\u8a66\u6d3b\u52d5\u3002\u9019\u4e9b\u898f\u5b9a\u96d6\u7136\u9084\u6c92\u6709\u5b9a\u6848\uff0c\u537b\u660e\u78ba\u6307\u51fa\uff0c\u7d14\u7cb9\u7528\u65bc\u8a3a\u65b7\u8207\u9810\u5f8c\u5206\u6790\u7684\u7b2c\u4e8c\u7d1a\u8a66\u9a57\uff08class II tests\uff09\uff0c\u53ef\u4ee5\u53ea\u900f\u904e\u7d44\u7e54\u9280\u884c\u7684\u6a23\u672c\u9032\u884c\u6e2c\u8a66\u3002\u4f46\u662f\u7b2c\u4e09\u7d1a\u8a66\u9a57\uff08class III tests\uff09\u56e0\u70ba\u6d89\u53ca\u91ab\u5e2b\u61c9\u8a72\u63a1\u7528\u54ea\u4e00\u7a2e\u6cbb\u7642\u6cd5\u7684\u554f\u984c\uff0c\u5be6\u9a57\u8a08\u756b\u5fc5\u9808\u7e7c\u7e8c\u8ffd\u8e64\u60a3\u8005\u7684\u60c5\u6cc1\uff0c\u6210\u672c\u4e5f\u6bd4\u8f03\u9ad8\u3002<\/p>\n

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\"\"<\/a>

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\u70ba\u82f1\u570b\u764c\u75c7\u7814\u7a76\uff08Cancer Research UK\uff09\u505a\u81e8\u5e8a\u5be6\u9a57\u7684\u66fc\u5fb9\u65af\u7279\u5927\u5b78\u653e\u5c04\u816b\u7624\u5c08\u5bb6\u666e\u840a\u65af\uff08Pat Price\uff09\u8aaa\uff0c\u7814\u767c\u751f\u7269\u6a19\u8a18\u9700\u8981\u5404\u7a2e\u63a8\u529b\u8207\u62c9\u529b\uff0c\u63a8\u3001\u62c9\u529b\u91cf\u901a\u5e38\u4f86\u81ea\u5927\u85e5\u5ee0\u3002\u666e\u840a\u65af\u9810\u6e2c\uff0c\u88fd\u85e5\u696d\u6703\u8d8a\u4f86\u8d8a\u91cd\u8996\u751f\u7269\u6a19\u8a18\uff0c\u56e0\u70ba\u672a\u4f86\u4e0d\u540c\u907a\u50b3\u4eba\u53e3\u7fa4\u9ad4\u9700\u8981\u4e0d\u540c\u7684\u85e5\u7269\uff0c\u85e5\u54c1\u5e02\u5834\u6703\u66f4\u52a0\u5206\u773e\u5316\u3002<\/p>\n

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EDRN\u662f\u500b\u7570\u6578\uff0c\u5b83\u82b1\u4e86\u5169\u5343\u516b\u767e\u842c\u7f8e\u5143\u7684\u9810\u7b97\uff0c\u5c08\u9580\u7528\u4f86\u9a57\u8b49\u8207\u75be\u75c5\u8a3a\u65b7\u6216\u9810\u5f8c\u5206\u6790\u6709\u95dc\u7684\u751f\u7269\u6a19\u8a18\u3002<\/p>\n

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\u9ebb\u5ddeAVEO\u88fd\u85e5\u516c\u53f8\u8cc7\u6df1\u526f\u7e3d\u88c1\u7f85\u8cd3\u68ee\uff08Murray Robinson\uff09\u8aaa\uff0c \u6297\u4e73\u764c\u85e5\u7269Herceptin\u7684\u6210\u529f\uff0c\u5df2\u7d93\u4ee4\u88fd\u85e5\u696d\u4eba\u58eb\u95dc\u6ce8\u3002<\/p>\n

\u745e\u58eb\u7f85\u6c0f\u5927\u85e5\u5ee0\uff08Roche\uff09\u7b49\u5927\u516c\u53f8\u4e5f\u958b\u59cb\u52aa\u529b\u5c0b\u6c42\u5925\u4f34\uff0c\u60f3\u5171\u540c\u7814\u767c\u91dd\u5c0d\u7279\u5b9a\u75be\u75c5\u8207\u89e3\u85e5\u7684\u751f\u7269\u6a19\u8a18\u3002\u9019\u7a2e\u4f5c\u6cd5\u4e5f\u8a31\u6703\u4f7f\u7f85\u6c0f\u5927\u85e5\u5ee0\u5c0d\u7814\u767c\u7368\u7acb\u7684\u751f\u7269\u6a19\u8a18\u6e2c\u8a66\u5de5\u5177\u7684\u5c0f\u516c\u53f8\u5931\u53bb\u8208\u8da3\u3002<\/p>\n

\u8377\u862d\u4e00\u5bb6\u764c\u75c7\u8a3a\u65b7\u79d1\u6280\u516c\u53f8Agendia\u7684\u7814\u767c\u9577\u4f2f\u7d0d\u8332\uff08Ren\u00e9 Bernards\uff09\u5c31\u8aaa\uff0c\u5927\u516c\u53f8\u5c0d\u4ed6\u5011\u7684\u6e2c\u8a66\u6280\u8853\u6c92\u8208\u8da3\uff0c\u8b93\u4ed6\u5f88\u5931\u671b\u3002 \u8a72\u516c\u53f8\u7814\u767c\u7684MammaPrint\uff0c\u65e8\u5728\u9810\u6e2c\u4e73\u764c\u5fa9\u767c\u7684\u53ef\u80fd\u6027\uff0c\u4e5f\u662f\u7f8e\u570bFDA\u7b2c\u4e00\u500b\u6279\u51c6\u7684\u591a\u91cd\u57fa\u56e0\u9810\u5f8c\u6e2c\u8a66\uff08multigene prognostic test \uff09\u6280\u8853\u3002<\/p>\n

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