{"id":77996,"date":"2018-04-13T07:00:43","date_gmt":"2018-04-12T23:00:43","guid":{"rendered":"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/?p=77996"},"modified":"2021-10-06T16:03:35","modified_gmt":"2021-10-06T08:03:35","slug":"%e5%9f%ba%e5%9b%a0%e9%8a%80%e8%a1%8cgenbank","status":"publish","type":"post","link":"http:\/\/localhost\/%e5%9f%ba%e5%9b%a0%e9%8a%80%e8%a1%8cgenbank\/","title":{"rendered":"\u57fa\u56e0\u9280\u884c(GenBank)"},"content":{"rendered":"<div class=\"pf-content\"><p><span style=\"color: #ff6600;\"><strong>\u57fa\u56e0\u9280\u884c(GenBank)<\/strong><\/span><br \/>\n<span style=\"color: #008000;\"><strong>\u81fa\u7063\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb \u67ef\u4e00\u5609<\/strong><\/span><\/p>\n<p>\u4f9d\u7167\u7f8e\u570b\u570b\u5bb6\u5065\u5eb7\u5c40 (National Institution of Health) \u7684\u8aaa\u660e\uff0c\u57fa\u56e0\u9280\u884c\u662f\u4e00\u500b\u5132\u5b58\u8fd1\u4e8c\u3001\u4e09\u5341\u842c\u7269\u7a2e\u7684\u6838\u82f7\u9178\u5e8f\u5217 (nucleotide sequence) \u7684\u8cc7\u6599\u5eab\uff0c\u7531<a href=\"https:\/\/www.ncbi.nlm.nih.gov\">\u7f8e\u570b\u570b\u5bb6\u751f\u7269\u6280\u8853\u4fe1\u606f\u4e2d\u5fc3<\/a> (National Center for Biotechnology Information, NCBI\uff09\u8ca0\u8cac\u7ba1\u7406\uff0c\u6bcf\u5169\u500b\u6708\u66f4\u65b0\u4e00\u6b21\uff0c\u4e26\u4e14\u5c0d\u5916\u516c\u958b\u3002\u9019\u4e9b\u5e8f\u5217\u8cc7\u6599\u5927\u591a\u4f86\u81ea\u500b\u5225\u79d1\u5b78\u5bb6\u7684\u8ca2\u737b\u6216\u662f\u6574\u500b\u7814\u7a76\u8a08\u5283\u7684\u8cc7\u6599\u63d0\u4f9b\u3002\u8a72\u8cc7\u6599\u5eab\u5b9a\u671f\u8207\u6b50\u6d32\u6838\u82f7\u9178\u6a94\u6848\u5eab\uff08European Nucleotide Archive\uff09\u3001\u65e5\u672cDNA\u8cc7\u6599\u9280\u884c\uff08DNA Data Bank of Japan\uff09\u4ea4\u63db\u8cc7\u6599[1]\u3002\u4e09\u8005\u56e0\u6b64\u5171\u540c\u7d44\u6210\u4e86\u570b\u969b\u6838\u82f7\u9178\u5e8f\u5217\u8cc7\u6599\u5eab\u5408\u4f5c (the International Nucleotide Sequence Database Collaboration, INSDC)\uff0c\u81f4\u529b\u65bc\u7372\u53d6\u53ca\u4fdd\u5b58\u6838\u82f7\u9178\u5e8f\u5217\u4fe1\u606f\uff0c\u70ba\u6578\u64da\u5efa\u7acb\u4e86\u6a19\u6e96\u683c\u5f0f\uff0c\u4f7f\u500b\u4eba\u548c\u7d44\u7e54\u66f4\u5bb9\u6613\u5c07\u6838\u82f7\u9178\u6578\u64da\u53ef\u9760\u4e14\u5168\u9762\u63d0\u4f9b\u5927\u773e\u4f7f\u7528\u3002<!--more--><\/p>\n<div id=\"attachment_77998\" style=\"width: 310px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2018\/03\/p77996_p2.png\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-77998\" class=\"wp-image-77998\" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2018\/03\/p77996_p2.png\" alt=\"\" width=\"300\" height=\"225\" \/><\/a><p id=\"caption-attachment-77998\" class=\"wp-caption-text\">\uff08\u5716\u7247\u4f86\u6e90\uff1a\u7dad\u57fa\u767e\u79d1\uff09<\/p><\/div>\n<p>\u57fa\u56e0\u9280\u884c\u6703\u6839\u64da\uff1a(1)\u5206\u985e\u5b78 (Taxonomic) \u53ca (2) \u7372\u53d6\u5e8f\u5217\u7684\u65b9\u6cd5\uff0c\u5c07\u5e8f\u5217\u8a18\u9304\u5230\u6578\u500b\u4e0d\u540c\u7684\u90e8\u9580 (division)\u3002\u5728\u5206\u985e\u5b78\u4e2d\u5171\u670912\u500b\u90e8\u9580\u5927\u81f4\u5c0d\u61c9\u65bc\u5e8f\u5217\u7684\u4f86\u6e90\uff0c\u5206\u5225\u70baSYN (\u5408\u6210\u751f\u7269, Synthetic)\u3001PHG (\u566c\u83cc\u9ad4, Phages)\u3001ENV (\u74b0\u5883\u6a23\u672c, Environmental samples)\u3001VRL (\u75c5\u6bd2, Viruses)\u3001BCT (\u7d30\u83cc, Bacteria)\u3001PLN (\u690d\u7269, Plants)\u3001MAM (\u5176\u4ed6\u54fa\u4e73\u985e, Other mammals)\u3001VRT (\u5176\u4ed6\u810a\u690e\u52a8\u7269, Other vertebrates)\u3001PRI (\u9748\u9577\u985e\u52d5\u7269, Primates)\u3001UNA (\u672a\u6ce8\u660e, Unannotated)\u3001ROD (\u9f20\u985e, Rodents)\u53caINV (\u7121\u810a\u690e\u52d5\u7269, Invertebrates)\u3002\u5728\u7372\u53d6\u5e8f\u5217\u65b9\u6cd5\u7684\u90e8\u9580\u4e2d\u6709\uff1aTSA (\u8f49\u9304\u7269\u7d44\u69cd\u8cc7\u6599, Transcriptome shotgun data)\u3001WGS (\u5168\u57fa\u56e0\u9ad4\u69cd\u8cc7\u6599, Whole-genome shotgun data)\u3001PAT (\u5177\u6709\u5c08\u5229\u7684\u5e8f\u5217, Patented sequences)\u3001GSS (\u57fa\u56e0\u7d44\u6aa2\u6e2c\u5e8f\u5217, Genome survey sequences)\u3001EST (\u8868\u73fe\u5e8f\u5217\u6a19\u7c64, Expressed sequence tags)\u3001HTG (\u9ad8\u901a\u91cf\u57fa\u56e0\u9ad4\u5b78, High-throughput genomic)\u3001STS (\u5e8f\u5217\u6a19\u8a18\u5340, Sequence tagged sites)\u53caHTC (\u9ad8\u901a\u91cfcDNA, High-throughput cDNA) \u7b498\u500b[2] \u3002<\/p>\n<div id=\"attachment_77999\" style=\"width: 400px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2018\/03\/p77996_p3.png\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-77999\" class=\"wp-image-77999 size-full\" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2018\/03\/p77996_p3.png\" alt=\"\" width=\"390\" height=\"384\" \/><\/a><p id=\"caption-attachment-77999\" class=\"wp-caption-text\">1983\u5e74Walter Goad\u5728GenBank\u6578\u64da\u5eab\u7684\u7d42\u7aef\u524d\u3002\uff08\u5716\u7247\u4f86\u6e90\uff1a\u7dad\u57fa\u767e\u79d1\uff0c\u5176\u8f49\u8f09\u7d93\u7f8e\u570b\u54f2\u5b78\u5b78\u6703\u6a94\u6848\u8a31\u53ef\uff09<\/p><\/div>\n<p>\u57fa\u56e0\u9280\u884c\u4e3b\u8981\u662f\u63d0\u4f9b\u53ca\u9f13\u52f5\u79d1\u5b78\u793e\u7fa4\u4e4b\u9593\u4e92\u76f8\u4ea4\u63db\u6700\u65b0\u53ca\u7d9c\u5408\u6027\u7684DNA\u5e8f\u5217\uff0c\u5e8f\u5217\u8cc7\u6599\u53ea\u53ef\u4ee5\u7531\u539f\u5bc4\u9001\u8005\u4fee\u6539\uff0c\u4f46\u662f\u57fa\u56e0\u9280\u884c\u9f13\u52f5\u7b2c\u4e09\u4eba\u63d0\u4f9b\u4fee\u6539\u610f\u898b[2] \u3002\u6240\u6709\u5e8f\u5217\u8cc7\u6599\u53ef\u4ee5\u900f\u904e\u57fa\u56e0\u9280\u884c\u7684\u96fb\u5b50\u50b3\u8f38\u7cfb\u7d71BankIt\u6216Sequin\u50b3\u9001\u3002\u57fa\u672c\u4e0a\uff0c\u57fa\u56e0\u9280\u884c\u5c0d\u65bc\u4f7f\u7528\u8a72\u8cc7\u6599\u5eab\u4e26\u6c92\u505a\u4ec0\u9ebc\u9650\u5236\uff0c\u4e0d\u904e\u4ecd\u9700\u6ce8\u610f\u9019\u4e9b\u5e8f\u5217\u6709\u53ef\u80fd\u88ab\u7533\u8acb\u5c08\u5229\u6216\u8457\u4f5c\u6b0a\u7b49\u667a\u6167\u8ca1\u7522\u6b0a\u3002\u7531\u65bc\uff0c\u57fa\u56e0\u9280\u884c\u6c92\u6709\u63d0\u4f9b\u5354\u52a9\u53d6\u5f97\u9019\u4e9b\u667a\u6167\u8ca1\u7522\u6b0a\u6388\u6b0a\u7684\u670d\u52d9\uff0c\u5982\u679c\u9700\u8981\u505a\u5546\u696d\u4e0a\u7528\u9014\u7b49\uff0c\u4ecd\u662f\u9700\u8981\u518d\u67e5\u8a62\u662f\u5426\u6709\u9700\u8981\u5411\u539f\u6b0a\u5229\u6240\u6709\u4eba\u53d6\u5f97\u6388\u6b0a(GenBank Overview) \u3002\u518d\u8005\uff0c\u7531\u65bc\u6709\u4e9b\u4f5c\u8005\u5728\u6295\u7a3f\u671f\u520a\u8ad6\u6587\u6642\uff0c\u671f\u520a\u6703\u8981\u6c42\u63d0\u4f9b\u8cc7\u6599\u5230\u516c\u958b\u5e8f\u5217\u8cc7\u6599\u5eab\u505a\u70ba\u520a\u767b\u7684\u689d\u4ef6\uff0c\u56e0\u6b64\uff0c\u4f5c\u8005\u5011\u53ef\u4ee5\u8981\u6c42\u57fa\u56e0\u9280\u884c\u5c0d\u65bc\u6240\u5bc4\u9001\u7684\u5e8f\u5217\uff0c\u5728\u4ed6\u5011\u8ad6\u6587\u9084\u6c92\u6709\u88ab\u671f\u520a\u767b\u51fa\u4f86\u4e4b\u524d\u4e0d\u8981\u516c\u958b\u3002\u7576\u7136\uff0c\u4f5c\u8005\u9700\u8981\u544a\u77e5\u57fa\u56e0\u9280\u884c\u9810\u8a08\u520a\u767b\u65e5\u671f\uff0c\u4ee5\u5229\u9280\u884c\u7684\u76f8\u95dc\u4f5c\u696d\u3002<\/p>\n<hr \/>\n<p><strong>\u53c3\u8003\u6587\u737b<\/strong><\/p>\n<ol>\n<li>Karen Clark, Ilene Karsch-Mizrachi,\u00a0David J. Lipman,\u00a0James Ostell, and\u00a0Eric W. Sayers, GenBank, <em>Nucleic Acids Res.<\/em> <strong>2016<\/strong> Jan.<\/li>\n<li>Dennis A. Benson, Mark Cavanaugh, Karen Clark, Ilene Karsch-Mizrachi, David J. Lipman, James Ostell and Eric W. Sayers, GenBank, <em>Nucleic Acids Research<\/em>, <strong>2013<\/strong>, Vol. 41.<\/li>\n<li>GenBank Overview: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/genbank\/\">https:\/\/www.ncbi.nlm.nih.gov\/genbank\/<\/a><\/li>\n<\/ol>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u57fa\u56e0\u9280\u884c(GenBank) \u81fa\u7063\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb \u67ef\u4e00\u5609 \u4f9d\u7167\u7f8e\u570b\u570b\u5bb6\u5065\u5eb7\u5c40 (National Institu&hellip;<\/p>\n","protected":false},"author":50,"featured_media":77997,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4828,110,4829,122,4832],"tags":[894,11224,11223,11222],"class_list":{"0":"post-77996","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","6":"hentry","7":"category-lifesciecne003-03","8":"category-lifesciecne00","9":"category-lifesciecne003-04","10":"category-lifescience004","11":"category-lifesciecne004-01","12":"tag-dna","14":"tag-11223","15":"tag-11222","16":"loop-entry","17":"cat-4828","18":"cat-110","19":"cat-4829","20":"cat-122","21":"cat-4832"},"views":2906,"_links":{"self":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/77996","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/users\/50"}],"replies":[{"embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/comments?post=77996"}],"version-history":[{"count":1,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/77996\/revisions"}],"predecessor-version":[{"id":85822,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/77996\/revisions\/85822"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/media\/77997"}],"wp:attachment":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/media?parent=77996"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/categories?post=77996"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/tags?post=77996"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}