{"id":42582,"date":"2013-08-06T16:33:01","date_gmt":"2013-08-06T08:33:01","guid":{"rendered":"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/?p=42582"},"modified":"2021-10-06T16:21:03","modified_gmt":"2021-10-06T08:21:03","slug":"%e5%9f%ba%e5%9b%a0%e9%87%8d%e8%a3%bd%ef%bc%88gene-duplication%ef%bc%89","status":"publish","type":"post","link":"http:\/\/localhost\/%e5%9f%ba%e5%9b%a0%e9%87%8d%e8%a3%bd%ef%bc%88gene-duplication%ef%bc%89\/","title":{"rendered":"\u57fa\u56e0\u91cd\u88fd\uff08Gene duplication\uff09"},"content":{"rendered":"<div class=\"pf-content\"><p><strong><span style=\"color: #ff6600;\">\u57fa\u56e0\u91cd\u88fd\uff08Gene duplication\uff09<\/span><br \/>\n<\/strong><strong><span style=\"color: #008000;\">\u570b\u7acb\u81fa\u7063\u5e2b\u7bc4\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb\u7814\u7a76\u52a9\u7406\u912d\u674f\u5029<\/span><\/strong><\/p>\n<p>DNA\u7684\u6578\u91cf\uff08copy\u6578\uff09\u53ef\u85c9\u7531\u57fa\u56e0\u91cd\u88fd\uff08gene duplication\uff09\u4e8b\u4ef6\u800c\u589e\u52a0\u3002\u57fa\u56e0\u91cd\u88fd\u4f9d\u7167\u53c3\u8207\u91cd\u88fd\u4e4b\u57fa\u56e0\u9ad4\u9577\u5ea6\u4e4b\u4e0d\u540c\u800c\u5206\u70ba\u4ee5\u4e0b\u5e7e\u500b\u985e\u578b\u3002<\/p>\n<p>\uff081\uff09 \u90e8\u5206\u57fa\u56e0\u91cd\u88fd\uff08partial\/internal gene duplication\uff09<br \/>\n\uff082\uff09 \u5b8c\u6574\u57fa\u56e0\u91cd\u88fd\uff08complete gene duplication\uff09<br \/>\n\uff083\uff09 \u90e8\u5206\u67d3\u8272\u9ad4\u91cd\u88fd\uff08partial chromosomal duplication\uff09<br \/>\n\uff084\uff09 \u5b8c\u6574\u67d3\u8272\u9ad4\u91cd\u88fd\uff08complete chromosomal duplication\uff09<br \/>\n\uff085\uff09 \u591a\u500d\u9ad4\u5316\/\u57fa\u56e0\u9ad4\u91cd\u88fd\uff08polyploidy\/genome duplication\uff09<\/p>\n<p>\u524d\u56db\u985e\u578b\u7686\u70ba\u5340\u57df\u6027\u7684\u57fa\u56e0\u91cd\u88fd\uff08regional duplication\uff09\u4e8b\u4ef6\uff0c\u91cd\u88fd\u5f8c\u4e26\u4e0d\u6703\u6539\u8b8a\u751f\u7269\u9ad4\u5167\u67d3\u8272\u9ad4\u7684\u6578\u91cf\u3002\u56e0\u6b64\uff0c\u4e00\u822c\u8a8d\u70ba\u591a\u500d\u9ad4\u5316\u4e8b\u4ef6\u5c0d\u6f14\u5316\u6240\u626e\u6f14\u7684\u89d2\u8272\u9060\u9060\u5927\u65bc\u5340\u57df\u6027\u4e4b\u57fa\u56e0\u91cd\u88fd\u3002\u7136\u800c\u8fd1\u4f86\u7684\u7814\u7a76\u986f\u793a\uff0c\u5340\u57df\u6027\u7684\u57fa\u56e0\u91cd\u88fd\u5728\u6f14\u5316\u4e0a\u4e5f\u626e\u6f14\u8457\u8209\u8db3\u8f15\u91cd\u7684\u89d2\u8272\u3002<\/p>\n<p>\u5340\u57df\u6027\u7684\u57fa\u56e0\u91cd\u88fd\u4e4b\u767c\u751f\u6a5f\u5236\u5982\u4e0b\u3002\u5728\u7d30\u80de\u9032\u884c\u6709\u7d72\u5206\u88c2\uff0c\u540c\u6e90\u67d3\u8272\u9ad4\u914d\u5c0d\u9032\u884c\u57fa\u56e0\u91cd\u7d44\uff08recombination\uff09\u6642\uff0c\u767c\u751f\u975e\u540c\u6e90\u5340\u57df\u4e92\u63db\uff0c\u4ea6\u5373\u4e0d\u5c0d\u7b49\u4e92\u63db\uff08unequal crossing-over\uff09\uff0c\u4f7f\u5f97\u6709\u4e9b\u914d\u5b50\u9ad4\uff08gamete\uff09\u5e36\u6709\u5169\u5957\u76f8\u540c\u7684\u57fa\u56e0\uff0c\u800c\u76f8\u5c0d\u7684\u6709\u4e9b\u914d\u5b50\u9ad4\u7684\u67d0\u57fa\u56e0\u5c31\u6d88\u5931\u4e86\u3002\u4ee5\u4e0b\u7528\u7c21\u55ae\u7684\u793a\u610f\u5716\uff08\u5716\u4e00\uff09\u4f86\u63cf\u8ff0\u4e0d\u5c0d\u7b49\u4e92\u63db\u9020\u6210\u57fa\u56e0\u91cd\u88fd\u4e4b\u4e8b\u4ef6\u3002<\/p>\n<div id=\"attachment_42583\" style=\"width: 690px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2013\/08\/f.png\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-42583\" class=\"size-full wp-image-42583\" title=\"f\" alt=\"\" src=\"http:\/\/highscope.ch.ntu.edu.tw\/wordpress\/wp-content\/uploads\/2013\/08\/f.png\" width=\"680\" height=\"177\" srcset=\"http:\/\/localhost\/wp-content\/uploads\/2013\/08\/f.png 1258w, http:\/\/localhost\/wp-content\/uploads\/2013\/08\/f-300x78.png 300w, http:\/\/localhost\/wp-content\/uploads\/2013\/08\/f-1024x266.png 1024w\" sizes=\"auto, (max-width: 680px) 100vw, 680px\" \/><\/a><p id=\"caption-attachment-42583\" class=\"wp-caption-text\">\u82f1\u6587\u5b57\u6bcd\u4ee3\u8868\u57fa\u56e0\u5728\u67d3\u8272\u9ad4\u4e0a\u7684\u4f4d\u7f6e\uff0c\u767d\u8272\u5713\u5708\u70ba\u4e2d\u5fc3\u7c92\u7684\u4f4d\u7f6e\u3002\u5de6\u5716\u986f\u793a\u806f\u6703\u4e8b\u4ef6\u767c\u5728\u975e\u540c\u6e90\u4e4b\u5340\u57df\uff0c\u56e0\u6b64\u7522\u72693\u591a\u4e86\u4e00\u500b\uff23\u57fa\u56e0\uff0c\u7522\u72692\u5247\u5c11\u4e86\u4e00\u500bC\u57fa\u56e0\u3002<\/p><\/div>\n<p>\u4e0d\u5c0d\u7b49\u4e92\u63db\u4e8b\u4ef6\u5e38\u767c\u751f\u5728\u67d3\u8272\u9ad4\u4e2d\u6709\u8a31\u591a\u91cd\u8907\u5e8f\u5217\u7684\u5730\u65b9\uff0c\u4e14\u4e00\u65e6\u767c\u751f\u4e86\u7b2c\u4e00\u6b21\u4e0d\u5c0d\u7b49\u4e92\u63db\uff0c\u6b64\u5340\u57df\u518d\u767c\u751f\u4e0d\u5c0d\u7b49\u4e92\u63db\u7684\u6a5f\u7387\u5247\u589e\u52a0\uff08\u56e0\u70ba\u6709\u66f4\u591a\u7684\u91cd\u8907\u5e8f\u5217\u63d0\u4f9b\u4e0d\u5c0d\u7b49\u4e92\u63db\u767c\u751f\uff09\uff0c\u56e0\u6b64\u5e38\u5e38\u53ef\u4ee5\u770b\u5230\u57fa\u56e0\u9ad4\u4e2d\u67d0\u4e00\u5340\u57df\u6709\u57fa\u56e0\u5bb6\u65cf\uff08gene family\uff09\u7684\u72c0\u6cc1\u3002\u7576\u91cd\u88fd\u4e8b\u4ef6\u7522\u751f\u5f8c\uff0c\u500b\u9ad4\u5167\u7684\u7b2c\u4e00\u5957\u57fa\u56e0\u8ca0\u8cac\u6b63\u5e38\u529f\u80fd\u904b\u4f5c\uff0c\u53e6\u5916\u591a\u9918\u7684\u7b2c\u4e8c\u5957\u57fa\u56e0\u5247\u53ef\u4ee5\u7d2f\u7a4d\u8b8a\u7570\u800c\u4e0d\u6703\u5f71\u97ff\u751f\u7269\u4e4b\u6b63\u5e38\u904b\u4f5c\uff0c\u7d93\u904e\u9577\u6642\u9593\u7684\u5929\u64c7\uff08natural selection\uff09\u6216\u662f\u4e2d\u6027\u7684\u907a\u50b3\u6f02\u8b8a\uff08genetic drift\uff09\u5f8c\uff0c\u7b2c\u4e8c\u5957\u57fa\u56e0\u6709\u6a5f\u6703\u53ef\u4ee5\u7d2f\u7a4d\u8db3\u5920\u7684\u8b8a\u7570\u800c\u6f14\u5316\u6210\u5177\u6709\u65b0\u529f\u80fd\u4e4b\u65b0\u57fa\u56e0\uff08new gene\uff09\u3002<!--more--><\/p>\n<p>\u6b64\u5916\uff0c\u57fa\u56e0\u91cd\u88fd\u4e00\u76f4\u88ab\u8996\u70ba\u57fa\u56e0\u9ad4\u5927\u5c0f\uff08genome size\uff09\u6f14\u5316\u7684\u91cd\u8981\u56e0\u5b50\u3002\u591a\u500d\u9ad4\u5316\u4e8b\u4ef6\uff08\u6216\u662f\u67d3\u8272\u9ad4\u6578\u76ee\u589e\u52a0\uff09\u90fd\u662f\u4f7f\u57fa\u56e0\u9ad4\u5927\u5c0f\u589e\u52a0\u7684\u91cd\u8981\u6210\u56e0\u3002\u7814\u7a76\u7269\u7a2e\u6f14\u5316\u7684\u6b77\u53f2\u53ef\u767c\u73fe\uff0c\u57fa\u56e0\u9ad4\u91cd\u88fd\u4e8b\u4ef6\u4e0d\u65b7\u7684\u91cd\u8907\u767c\u751f\uff0c\u4e14\u6bcf\u4e00\u6b21\u57fa\u56e0\u9ad4\u91cd\u88fd\u4e8b\u4ef6\u767c\u751f\u5f8c\uff0c\u5e38\u96a8\u5f8c\u4f34\u96a8\u7269\u7a2e\u5927\u7206\u767c\uff0c\u4e5f\u5c31\u662f\u6709\u8a31\u591a\u65b0\u7269\u7a2e\u7522\u751f\u3002\u4ee5\u4e0a\u53ef\u898b\u57fa\u56e0\u91cd\u88fd\u4e8b\u4ef6\u4e0d\u50c5\u53ef\u4ee5\u9a45\u52d5\u65b0\u57fa\u56e0\u7684\u751f\u6210\uff0c\u66f4\u662f\u7269\u7a2e\u6f14\u5316\u7684\u91cd\u8981\u63a8\u624b\u3002<\/p>\n<p>\u53c3\u8003\u8cc7\u6599\uff1a<\/p>\n<p>Dan Graur &amp; Wen-Hsiung Li. 2000. Fundamentals of molecular evolution. 2<sup>nd<\/sup> edition. p250.<\/p>\n<p>Daniel L. Hartl &amp; Andrew G. Clark. Principles of population genetics. 4<sup>th<\/sup> edition. p372-373.<\/p>\n<p>Scott <a href=\"http:\/\/www.amazon.com\/s\/ref=ntt_athr_dp_sr_1?_encoding=UTF8&amp;field-author=Jon%20C.%20Freeman%20Scott%20and%20Herron&amp;search-alias=books&amp;sort=relevancerank\">Freeman &amp; Jon C. Herron<\/a>. Evolutionary Analysis. 3<sup>rd<\/sup> edition. p120-121.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u57fa\u56e0\u91cd\u88fd\uff08Gene duplication\uff09 \u570b\u7acb\u81fa\u7063\u5e2b\u7bc4\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb\u7814\u7a76\u52a9\u7406\u912d\u674f\u5029 DNA\u7684\u6578\u91cf\uff08copy&hellip;<\/p>\n","protected":false},"author":50,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4810,110,4817],"tags":[894,4685,2458,4684,4608],"class_list":["post-42582","post","type-post","status-publish","format-standard","hentry","category-lifesciecne001","category-lifesciecne00","category-lifesciecne001-01","tag-dna","tag-gene-duplication","tag-2458","tag-4684","tag-4608","loop-entry","cat-4810","cat-110","cat-4817","no-thumbnail"],"views":6911,"_links":{"self":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/42582","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/users\/50"}],"replies":[{"embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/comments?post=42582"}],"version-history":[{"count":1,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/42582\/revisions"}],"predecessor-version":[{"id":87611,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/posts\/42582\/revisions\/87611"}],"wp:attachment":[{"href":"http:\/\/localhost\/wp-json\/wp\/v2\/media?parent=42582"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/categories?post=42582"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/localhost\/wp-json\/wp\/v2\/tags?post=42582"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}