{"id":9321,"date":"2011-06-27T12:47:35","date_gmt":"2011-06-27T04:47:35","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=9321"},"modified":"2017-03-31T23:20:41","modified_gmt":"2017-03-31T15:20:41","slug":"%e3%80%90%e7%94%9f%e7%89%a9%e9%86%ab%e5%ad%b8%e3%80%91%e7%aa%88%e7%aa%95%e8%80%81%e7%85%99%e6%a7%8d%e4%b9%8b%e8%ac%8e%e8%a7%a3%e9%96%8b%e4%ba%86","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=9321","title":{"rendered":"\u3010\u751f\u7269\u91ab\u5b78\u3011\u7a88\u7a95\u8001\u7159\u69cd\u4e4b\u8b0e\u89e3\u958b\u4e86"},"content":{"rendered":"<p><span style=\"color: #800000;\"><strong>\u25a0 \u6212\u7159\u6703\u767c\u80d6\uff0c\u9019\u662f\u4e00\u7a2e\u5e38\u8b58\u3002\u6709\u4e9b\u4eba\u5be7\u53ef\u7e7c\u7e8c\u7576\u7159\u69cd\u4e5f\u4e0d\u9858\u610f\u81ea\u5df1\u80c3\u53e3\u5927\u958b\uff0c\u4e0d\u904e\u7a76\u7adf\u9999\u83f8\u4f55\u4ee5\u80fd\u5920\u964d\u4f4e\u98df\u617e\u5462\uff1f<\/strong><\/span><\/p>\n<figure id=\"attachment_9330\" aria-describedby=\"caption-attachment-9330\" style=\"width: 758px\" class=\"wp-caption alignnone\"><a href=\"http:\/\/www.flickr.com\/photos\/gifake\/5375809738\/in\/photostream\/lightbox\/\" target=\"_blank\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-9330\" title=\"r9M@flickr\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2011\/06\/r9M@flickr.jpg\" alt=\"\" width=\"758\" height=\"539\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2011\/06\/r9M@flickr.jpg 758w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2011\/06\/r9M@flickr-600x427.jpg 600w\" sizes=\"(max-width: 758px) 100vw, 758px\" \/><\/a><figcaption id=\"caption-attachment-9330\" class=\"wp-caption-text\">\u4ee5\u9aa8\u611f\u9ad4\u578b\u6df1\u690d\u4eba\u5fc3\u7684\u5973\u660e\u661f\u5967\u9edb\u9e97\u2027\u8d6b\u672c\uff0c\u5077\u9592\u5438\u7159\u4e2d\u3002<\/figcaption><\/figure>\n<p><strong>\u7de8\u8b6f<\/strong> \u2223 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Mineur\uff09\u7387\u9818\u6821\u5167\u540c\u4ec1\u9032\u884c\u76f8\u95dc\u7814\u7a76\uff0c\u63d0\u51fa\u4e86\u4e00\u4e9b\u89e3\u7b54\u3002\u7814\u7a76\u5718\u968a\u5df2\u7d93\u627e\u51fa\u5c3c\u53e4\u4e01\u964d\u4f4e\u52d5\u7269\u98df\u91cf\u7684\u9014\u5f91\uff0c\u9019\u4efd\u7814\u7a76\u6210\u679c\u6216\u8a31\u6709\u52a9\u4e16\u4eba\u505c\u6b62\u62bd\u7159\uff0c\u4e26\u53ef\u9032\u4e00\u6b65\u767c\u5c55\u51fa\u6cbb\u7642\u80a5\u80d6\u75c7\u7684\u65b0\u65b9\u6cd5\u3002\u672c\u8ad6\u6587\u5df2\u520a\u767b\u57286\u670810\u65e5\u7684\u300a\u79d1\u5b78\u300b\uff08<em>Science<\/em>\uff09\u671f\u520a\u88e1\u3002<\/p>\n<p><!--more--><\/p>\n<p>\u3000\u3000\u7c73\u7d0d\u723e\u5728\u7814\u7a76\u4e2d\u767c\u73fe\uff0c\u5c3c\u53e4\u4e01\u548c\u4e00\u7a2e\u540d\u70ba\u91d1\u96c0\u82b1\u9e7c\uff08cytisine\uff09\u7684\u85e5\u7269\u90fd\u80fd\u6291\u5236\u8001\u9f20\u7684\u98df\u7269\u651d\u53d6\u91cf\uff0c\u6700\u591a\u53ef\u6e1b\u5c1150%\uff0c\u6b64\u5916\u4e5f\u80fd\u6e1b\u5c11\u5927\u7d0415%\u81f320%\u7684\u9ad4\u8102\u91cf\uff0c\u5176\u4e2d\u5c3c\u53e4\u4e01\u6703\u9644\u8457\u5728\u8001\u9f20\u4e2d\u6a1e\u53ca\u5468\u908a\u795e\u7d93\u7cfb\u7d71\u7684\u5c3c\u53e4\u4e01\u4e59\u91af\u81bd\u9e7c\u53d7\u9ad4\uff08nicotinic 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nucleus\uff09\u795e\u7d93\u5143\u4e2d\u7522\u751f\u4f5c\u7528\uff0c\u7531\u6b64\u53ef\u898b\u5c3c\u53e4\u4e01\u6291\u5236\u98df\u617e\u7684\u4f5c\u7528\u4e3b\u8981\u5c31\u5728\u9019\u4e9b\u7d30\u80de\u4e0a\u3002<\/p>\n<p>\u3000\u3000\u7814\u7a76\u4eba\u54e1\u6839\u64da\u963b\u65b7\u03b24\u6b21\u55ae\u5143\u6240\u5f97\u5230\u7684\u5be6\u9a57\u7d50\u679c\uff0c\u9032\u4e00\u6b65\u7814\u7a76\u4e0b\u8996\u4e18\u4e2d\u57fa\u90e8\u88e1\u5404\u7a2e\u795e\u7d93\u5143\u7684\u529f\u80fd\u3002\u5c3c\u53e4\u4e01\u4e59\u91af\u81bd\u9e7c\u53d7\u9ad4\u03b24\u6b21\u55ae\u5143\u7684\u4f5c\u7528\u6703\u8868\u73fe\u5728\u4e00\u985e\u7a31\u70baPOMC\uff08pro-opiomelanocortin\uff0c\u5373\u300e\u524d-\u8166\u5561-\u9ed1\u7d30\u80de\u4fc3\u7d20-\u76ae\u4fc3\u7d20\u300f\uff09\u7684\u795e\u7d93\u7d30\u80de\u4e0a\u3002\u7814\u7a76\u5718\u968a\u767c\u73fe\uff0c\u83f8\u9e7c\u85e5\u7269\u6703\u9644\u8457\u5728POMC\u795e\u7d93\u5143\u7684\u5c3c\u53e4\u4e01\u4e59\u91af\u81bd\u9e7c\u53d7\u9ad4\u4e0a\uff0c\u4fc3\u4f7f\u9019\u4e9bPOMC\u7d30\u80de\u91cb\u653e\u6fc0\u7d20\u3002<\/p>\n<p>\u3000\u3000\u7814\u7a76\u4eba\u54e1\u5728POMC\u795e\u7d93\u5143\u4e0a\u65bd\u6253\u5c3c\u53e4\u4e011\u81f32\u5206\u9418\uff0cPOMC\u7d30\u80de\u91cb\u653e\u6fc0\u7d20\u7684\u983b\u7387\u4fbf\u589e\u9ad8\u4e86\uff0c\u6548\u679c\u4f9d\u65bd\u6253\u7684\u91cf\u800c\u6709\u6240\u4e0d\u540c\uff0c0.5\u5fae\u7c73\u7684\u4f4e\u5291\u91cf\u6703\u5c0e\u81f4\u983b\u7387\u5347\u9ad81.73\u500d\uff0c50\u5fae\u7c73\u7684\u9ad8\u5291\u91cf\u5247\u6703\u5c0e\u81f4\u983b\u7387\u5347\u9ad84.56\u500d\u3002\u6fc0\u5316POMC\u795e\u7d93\u5143\u6703\u964d\u4f4e\u98df\u617e\uff0c\u4e26\u589e\u52a0\u80fd\u91cf\u6d88\u8017\uff0c\u9019\u662f\u904e\u53bb\u5df2\u77e5\u7684\u4e8b\u5be6\u3002\u5177\u9ad4\u800c\u8a00\uff0c\u7c73\u7d0d\u723e\u548c\u7814\u7a76\u5718\u968a\u767c\u73fe\uff0cPOMC\u795e\u7d93\u5143\u6240\u91cb\u653e\u4e00\u7a2e\u7a31\u70ba\u9ed1\u8272\u7d20\u76ae\u8cea\u7d20\uff08melanocortin\uff09\u7684\u6fc0\u7d20\uff0c\u6b63\u662f\u8b93\u5c3c\u53e4\u4e01\u7522\u751f\u6291\u5236\u98df\u617e\u6548\u679c\u7684\u95dc\u9375\u3002<\/p>\n<p>\u3000\u3000\u6574\u500b\u904e\u7a0b\u7e3d\u7d50\u5982\u4e0b\uff1a\u7c73\u7d0d\u723e\u767c\u73fe\u5c3c\u53e4\u4e01\u53ca\u5176\u4ed6\u83f8\u9e7c\u85e5\u7269\u6291\u5236\u98df\u617e\u7684\u6a5f\u5236\uff0c\u5c31\u662f\u8207\u5c3c\u53e4\u4e01\u4e59\u91af\u81bd\u9e7c\u53d7\u9ad4\u7684\u03b24\u6b21\u55ae\u5143\u8d77\u4f5c\u7528\uff0c\u6fc0\u5316POMC\u795e\u7d93\u5143\uff0c\u4f7f\u5176\u91cb\u653e\u9ed1\u8272\u7d20\u76ae\u8cea\u7d20\u3002\u9019\u4efd\u7814\u7a76\u7684\u4f5c\u8005\u7fa4\u6307\u51fa\uff0c\u8207\u6291\u5236\u98df\u617e\u6548\u679c\u76f8\u95dc\u7684\u53ef\u80fd\u4e0d\u53ea\u6709\u03b24\u6b21\u55ae\u5143\uff0c\u5982\u679c\u9032\u4e00\u6b65\u7814\u7a76\uff0c\u6216\u8a31\u80fd\u627e\u51fa\u5176\u4ed6\u626e\u6f14\u91cd\u8981\u89d2\u8272\u7684\u5c3c\u53e4\u4e01\u4e59\u91af\u81bd\u9e7c\u53d7\u9ad4\u6b21\u55ae\u5143\u3002<\/p>\n<p>\u3000\u3000\u7c73\u7d0d\u723e\u548c\u7814\u7a76\u540c\u4ec1\u63ed\u958b\u4e86\u5c3c\u53e4\u4e01\u6291\u5236\u98df\u617e\u7684\u6a5f\u5236\uff0c\u958b\u555f\u4e00\u9053\u5927\u9580\uff0c\u672a\u4f86\u79d1\u5b78\u5bb6\u53ef\u671b\u64da\u6b64\u767c\u5c55\u6c92\u6709\u83f8\u985e\u7522\u54c1\u5f0a\u5bb3\u7684\u6e1b\u91cd\u7642\u6cd5\uff0c\u4f8b\u5982\u6216\u8a31\u80fd\u5408\u6210\u51fa\u6bd4\u5c3c\u53e4\u4e01\u6bd2\u6027\u4f4e\u800c\u4e0d\u6613\u6210\u766e\u7684\u85e5\u7269\uff0c\u4f46\u53c8\u80fd\u5c0d\u8166\u90e8\u7522\u751f\u985e\u4f3c\u6a5f\u5236\uff0c\u9019\u6a23\u7684\u85e5\u7269\u5c07\u53ef\u5e6b\u52a9\u4e16\u4eba\u6709\u6548\u5c0d\u6297\u80a5\u80d6\u75c7\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<pre><span style=\"color: #333333;\">\u7814\u7a76\u51fa\u8655\uff1a<\/span><a href=\"http:\/\/www.sciencemag.org\/content\/332\/6035\/1330\" target=\"_blank\"><span style=\"color: #333333;\">Nicotine Decreases Food Intake Through Activation of POMC Neurons<\/span><\/a><span style=\"color: #333333;\">\uff08<em>Science<\/em>\uff09<\/span><\/pre>\n<p><strong><span style=\"color: #003366;\">\u8cac\u4efb\u7de8\u8f2f\uff1aMissZoe<\/span><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0 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