{"id":8192,"date":"2011-03-23T14:56:49","date_gmt":"2011-03-23T06:56:49","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=8192"},"modified":"2017-03-31T23:20:46","modified_gmt":"2017-03-31T15:20:46","slug":"%e3%80%90%e7%94%9f%e7%89%a9%e9%86%ab%e5%ad%b8%e3%80%91%e8%ae%93%e7%94%9f%e7%89%a9%e6%a8%99%e8%a8%98%e4%b8%8a%e5%a0%b4%ef%bc%81","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=8192","title":{"rendered":"\u3010\u751f\u7269\u91ab\u5b78\u3011\u8b93\u751f\u7269\u6a19\u8a18\u4e0a\u5834\uff01"},"content":{"rendered":"<p><span style=\"color: #003366;\"><strong>\u25a0 \u4ee5\u751f\u7269\u6a19\u8a18\u4f86\u4f5c\u70ba\u75be\u75c5\u8a3a\u65b7\u95dc\u806f\u6307\u6a19\u7684\u7814\u7a76\uff0c\u904e\u53bb\u7522\u751f\u6578\u5341\u842c\u7bc7\u8ad6\u6587\uff0c\u4e0a\u5343\u500b\u751f\u7269\u6a19\u8a18\uff0c\u4f46\u5728\u81e8\u5e8a\u4e0a\u767c\u63ee\u7684\u6548\u679c\u6709\u9650\u3002\u6ce2\u65af\u7279\u8a8d\u70ba\u9019\u4e9b\u5206\u6563\u96f6\u788e\u7684\u52aa\u529b\u61c9\u8a72\u6709\u7cfb\u7d71\u5730\u6574\u5408\uff0c\u624d\u80fd\u767c\u63ee\u6700\u5927\u6548\u7528\u3002<\/strong><\/span><\/p>\n<figure id=\"attachment_8193\" aria-describedby=\"caption-attachment-8193\" style=\"width: 614px\" class=\"wp-caption alignnone\"><a href=\"http:\/\/www.flickr.com\/photos\/emsl\/4704802544\/in\/photostream\/\" target=\"_blank\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-8193 \" title=\"EMSL@flickr\" alt=\"\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2011\/03\/EMSL@flickr.jpg\" width=\"614\" height=\"524\" \/><\/a><figcaption id=\"caption-attachment-8193\" class=\"wp-caption-text\">\u751f\u7269\u6a19\u8a18\u88ab\u8a8d\u70ba\u662f\u75be\u75c5\u6cbb\u7642\u7684\u65b0\u5e0c\u671b\uff0c\u4f46\u4ecd\u9808\u8cc7\u6e90\u6574\u5408<\/figcaption><\/figure>\n<p>\u5982\u679c\u7814\u7a76\u4eba\u54e1\u53ef\u4ee5\u78ba\u7acb\u75be\u75c5\u548c\u751f\u7269\u6a19\u8a18\uff08biomarkers\uff09\u8b8a\u5316\u7684\u76f8\u95dc\u6027\uff0c\u5c0d\u91ab\u751f\u8a3a\u65b7\u75be\u75c5\u53ca\u9032\u884c\u500b\u9ad4\u6cbb\u7642\u5c07\u5927\u6709\u5e6b\u52a9\u3002\u7136\u800c\uff0c\u5c0d\u65bc\u751f\u7269\u6a19\u8a18\uff0c\u4e5f\u5c31\u662f\u5c0d\u65bc\u751f\u7269\u9ad4\u7d44\u7e54\u6216\u9ad4\u6db2\u7684\u5206\u5b50\u6539\u8b8a\uff0c\u548c\u75be\u75c5\u4e4b\u9593\u95dc\u806f\u6027\u7684\u7814\u7a76\u7d50\u679c\u5c1a\u5f85\u8b49\u5be6\u3002\u96a8\u8457\u86cb\u767d\u8cea\u9ad4\u5b78\u4ee5\u53caDNA\u5fae\u9663\u5217\u6280\u8853\u7b49\u79d1\u6280\u7684\u767c\u5c55\uff0c\u5df2\u6709\u8d85\u904e\u5341\u4e94\u842c\u7bc7\u7684\u8ad6\u6587\u767c\u8868\uff0c\u5176\u4e2d\u8072\u7a31\u7684\u751f\u7269\u6a19\u8a18\u6578\u4ee5\u5343\u8a08\uff0c\u4f46\u662f\u7d93\u81e8\u5e8a\u5be6\u9a57\u8b49\u5be6\u7684\u537b\u4e0d\u5230\u4e00\u767e\u500b\uff0c\u6b64\u61f8\u6b8a\u6bd4\u4f8b\u53cd\u6620\u51fa\u7814\u7a76\u4eba\u54e1\u4e26\u672a\u63a1\u7528\u6574\u5408\u6027\u7684\u7cfb\u7d71\u7814\u7a76\u65b9\u6cd5\u3002<\/p>\n<p>\u8a31\u591a\u6162\u6027\u75be\u75c5\u727d\u6d89\u5230\u591a\u91cd\u5206\u5b50\u8def\u5f91\uff08molecular pathways\uff09\uff0c\u4f46\u8981\u8b49\u5be6\u75be\u75c5\u8207\u4e00\u5927\u7d44\u751f\u7269\u6a19\u8a18\u7684\u95dc\u806f\u6027\uff0c\u537b\u76f8\u7576\u56f0\u96e3\u3002\u5c0b\u627e\u751f\u7269\u6a19\u8a18\u9700\u8981\u8db3\u5920\u8cc7\u6e90\u53ca\u591a\u9818\u57df\u7684\u5c08\u696d\u6280\u8853\uff0c\u624d\u80fd\u5efa\u7acb\u751f\u7269\u6a19\u8a18\u8207\u4eba\u9ad4\u5065\u5eb7\u72c0\u6cc1\u6216\u6cbb\u7642\u53cd\u61c9\u7684\u660e\u78ba\u95dc\u806f\u6027\uff0c\u7136\u800c\u5927\u591a\u5b78\u8853\u55ae\u4f4d\u5be6\u9a57\u5ba4\u9032\u884c\u7684\u7814\u7a76\uff0c\u537b\u6b63\u597d\u7f3a\u4e4f\u9019\u6a23\u7684\u689d\u4ef6\u3002\u6b64\u5916\uff0c\u8981\u5c0d\u773e\u591a\u5019\u9078\u751f\u7269\u6a19\u8a18\u9032\u884c\u5927\u898f\u6a21\u9a57\u8b49\u7814\u7a76\uff0c\u9084\u8981\u7a81\u7834\u8cc7\u6e90\u63d0\u4f9b\u548c\u6cd5\u898f\u9762\u7684\u9650\u5236\u3002\u514b\u670d\u9019\u4e9b\u56f0\u96e3\u5fc5\u9808\u6574\u5408\u4e0d\u540c\u7684\u6280\u8853\u3002<\/p>\n<p><!--more--><\/p>\n<p>\u5fc5\u9808\u6539\u8b8a\u7684\u9084\u5305\u62ec\u5c07\u7814\u7a76\u65b9\u6cd5\u6a19\u6e96\u5316\uff0c\u4e26\u8490\u96c6\u8db3\u5920\u6578\u91cf\u7684\u6a23\u672c\u4ee5\u9032\u884c\u9a57\u8b49\u8a66\u9a57\u3002\u50b3\u7d71\u4e0a\uff0c\u7531\u7814\u7a76\u4eba\u54e1\u81ea\u884c\u958b\u59cb\u7684\u7368\u7acb\u7814\u7a76\u6a21\u5f0f\uff0c\u5fc5\u9808\u6539\u8b8a\u70ba\u300c\u5927\u79d1\u5b78\u300d\u8a08\u756b\u6240\u4e00\u5411\u63a1\u7528\u7684\u5408\u4f5c\u7814\u7a76\u6a21\u5f0f\uff0c\u4f8b\u5982\u7f8e\u570b\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662\u70ba\u764c\u75c7\u57fa\u56e0\u7d44\u8b8a\u5316\u7de8\u88fd\u76ee\u9304\uff0c\u6240\u9032\u884c\u7684\u764c\u75c7\u57fa\u56e0\u5716\u8b5c\u8a08\u756b\u3002\u751f\u7269\u6a19\u8a18\u641c\u5c0b\u7684\u5de5\u7a0b\uff0c\u61c9\u8a72\u5efa\u69cb\u5728\u9f90\u5927\u7684\u7814\u7a76\u7db2\u8def\u4e0a\uff0c\u7d50\u5408\u4f86\u81ea\u5206\u5b50\u751f\u7269\u3001\u57fa\u56e0\u3001\u5206\u6790\u5316\u5b78\u3001\u8a08\u7b97\u3001\u5de5\u7a0b\u3001\u81e8\u5e8a\u8a66\u9a57\u8a2d\u8a08\u3001\u6d41\u884c\u75c5\u5b78\u3001\u7d71\u8a08\u3001\u6cd5\u898f\u53ca\u5065\u5eb7\u7167\u8b77\u7d93\u6fdf\u7b49\u4e0d\u540c\u9818\u57df\u7684\u5c08\u5bb6\u8207\u696d\u8005\u3002<\/p>\n<p>\u9577\u4e45\u4ee5\u4f86\uff0c\u751f\u7269\u6a19\u8a18\u88ab\u8a8d\u70ba\u662f\u6539\u5584\u75c5\u4eba\u7167\u8b77\u4ee5\u53ca\u964d\u4f4e\u91ab\u7642\u6210\u672c\u7684\u95dc\u9375\u56e0\u7d20\u3002\u4f8b\u5982\u6839\u64da\u7f8e\u570b\u81e8\u5e8a\u816b\u7624\u5354\u6703\u7684\u4f30\u8a08\uff0c\u5c0d\u5927\u8178\u764c\u60a3\u8005\u7d93\u5e38\u6027\u5730\u9032\u884cK-RAS\u81f4\u764c\u57fa\u56e0\u7a81\u8b8a\u7684\u6aa2\u9a57\uff0c\u4e00\u5e74\u81f3\u5c11\u53ef\u4ee5\u7bc0\u7701\u516d\u767e\u842c\u7f8e\u5143\u7684\u652f\u51fa\u3002\u751f\u7269\u6a19\u8a18\u4e26\u53ef\u514d\u53bb\u75c5\u4eba\u627f\u53d7\u7121\u6548\u53c8\u6709\u6f5b\u5728\u6bd2\u6027\u7684\u7642\u7a0b\uff0c\u4f8b\u5982\u5c0d\u65bc\u6709K-RAS\u81f4\u764c\u57fa\u56e0\u7a81\u8b8a\u7684\u60a3\u8005\u4f86\u8aaa\uff0c\u4f7f\u7528\u6291\u5236\u4e0a\u76ae\u7d30\u80de\u751f\u9577\u56e0\u5b50\u53d7\u9ad4(EGFR)\u85e5\u7269\u6cbb\u7642\uff0c\u6c92\u6709\u6548\u7528\uff0c\u4f46\u6bcf\u6b21\u6cbb\u7642\u6210\u672c\u9ad8\u9054\u5341\u842c\u7f8e\u5143\u3002<\/p>\n<p><strong>\u860b\u679c\u548c\u6a58\u5b50<\/strong><\/p>\n<p>\u641c\u5c0b\u751f\u7269\u6a19\u8a18\u6240\u9762\u81e8\u7684\u4e00\u5927\u96e3\u984c\uff0c\u662f\u6c92\u6709\u6a19\u6e96\u5316\u7684\u63a1\u6a23\u65b9\u6cd5\u3002\u9664\u975e\u6a23\u672c\u662f\u5f9e\u7b26\u5408\u6700\u591a\u8b8a\u7570\u7684\u4eba\u9078\u8eab\u4e0a\u63a1\u5f97\uff0c\u5426\u5247\u5f8c\u7e8c\u89c0\u5bdf\u751f\u7269\u6a19\u8a18\u8207\u4eba\u9ad4\u60c5\u6cc1\u4ee5\u53ca\u6cbb\u7642\u53cd\u61c9\u95dc\u806f\u6027\u7684\u6b65\u9a5f\uff0c\u90fd\u662f\u5728\u6709\u9650\u689d\u4ef6\u4e0b\u7684\u7d50\u679c\u3002\u56e0\u6b64\u81f3\u5c11\u61c9\u8981\u6c42\u78ba\u8a8d\u63a1\u6a23\u4f86\u6e90\u4eba\u58eb\u7684\u6027\u5225\u3001\u5e74\u9f61\u3001\u9ad4\u91cd\u3001\u7a2e\u65cf\u3001\u751f\u6d3b\u578b\u614b\uff08\u4f8b\u5982\u5438\u7159\u559d\u9152\uff09\u3001\u4ee5\u53ca\u904e\u5f80\u63a5\u53d7\u91ab\u7642\u7684\u7d00\u9304\u7b49\u8b8a\u6578\u689d\u4ef6\u76f8\u540c\u3002\u7136\u800c\uff0c\u8a55\u4f30\u75c5\u4eba\u672c\u4f86\u5c31\u6709\u4e0d\u540c\u65b9\u6cd5\uff0c\u4e0d\u540c\u570b\u5bb6\u3001\u4e0d\u540c\u91ab\u9662\u3001\u4e0d\u540c\u91ab\u751f\u5c0d\u75c5\u4eba\u7684\u8a3a\u65b7\u5831\u544a\uff0c\u4e5f\u6703\u6709\u5dee\u7570\uff0c\u6240\u4ee5\u5be6\u52d9\u4e0a\u641c\u5c0b\u751f\u7269\u6a19\u8a18\uff0c\u5e7e\u4e4e\u7121\u6cd5\u64c1\u6709\u9019\u6a23\u7684\u7406\u60f3\u689d\u4ef6\u3002<\/p>\n<p>\u592a\u591a\u7814\u7a76\u4eba\u54e1\u53ea\u80fd\u4f7f\u7528\u5f9e\u7576\u5730\u91ab\u9662\u65b9\u4fbf\u53d6\u5f97\u7684\u4efb\u4f55\u6a23\u672c\uff0c\u9019\u4e9b\u6a23\u672c\u53ef\u80fd\u4f86\u81ea\u75c5\u7406\u5be6\u9a57\u5ba4\u7684\u56fa\u5b9a\u7d44\u7e54\uff0c\u5176\u6709\u7528\u6027\u6703\u56e0\u75c5\u6b77\u8a18\u8f09\u4e0d\u7576\u6216\u672a\u7372\u6350\u8d08\u8005\u540c\u610f\u800c\u53d7\u9650\u3002\u8a31\u591a\u751f\u7269\u6a19\u8a18\u7814\u7a76\uff0c\u662f\u5728\u57f9\u990a\u7684\u7d30\u80de\u682a\u4e0a\u9032\u884c\uff0c\u4ee5\u66ff\u4ee3\u75c5\u60a3\u7d44\u7e54\u6a23\u672c\uff0c\u4f46\u53ea\u6709\u5728\u7814\u7a76\u4eba\u54e1\u80fd\u8b49\u5be6\u6b64\u7d30\u80de\u682a\u8207\u4eba\u9ad4\u4e2d\u7684\u540c\u7b49\u7d30\u80de\u6027\u8cea\u76f8\u540c\uff0c\u9019\u6a23\u7684\u7814\u7a76\u624d\u6709\u50f9\u503c\u3002<\/p>\n<p>\u6a23\u672c\u8655\u7406\u8207\u5132\u5b58\u7684\u7a0b\u5e8f\uff0c\u5c0d\u751f\u7269\u6a19\u8a18\u6e2c\u51fa\u7a0b\u5ea6\u4e5f\u6709\u91cd\u5927\u5f71\u97ff\uff0c\u56e0\u6b64\u5fc5\u9808\u6a19\u6e96\u5316\u3002\u7136\u800c\u6b64\u7a0b\u5e8f\u7d30\u7bc0\u5f88\u5c11\u4ee5\u6587\u4ef6\u8a18\u8f09\u3002\u7f8e\u570b\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662\u5728\u4e8c\u25cb\u25cb\u4e5d\u5e74\u7684\u8abf\u67e5\u5831\u544a\uff0c\u8d85\u904e\u4e03\u767e\u500b\u5be6\u9a57\u5ba4\u7814\u7a76\u54e1\u7684\u56de\u5fa9\u610f\u898b\u4e2d\uff0c\u767e\u5206\u4e4b\u516b\u5341\u8868\u793a\u4ed6\u5011\u5f88\u96e3\u5c31\u751f\u7269\u6a19\u8a18\u7814\u7a76\uff0c\u53d6\u5f97\u6a19\u6e96\u5316\u6a23\u672c\u3002\u53e6\u4e00\u8b66\u8a0a\u5247\u662f\uff0c\u540c\u6a23\u6709\u767e\u5206\u4e4b\u516b\u5341\u7684\u7814\u7a76\u4eba\u54e1\uff0c\u4e0d\u8cea\u7591\u6a23\u672c\u54c1\u8cea\u6216\u8655\u7406\u65b9\u5f0f\u6703\u5f71\u97ff\u5230\u7814\u7a76\u7684\u7d50\u679c\u3002<\/p>\n<p>\u63a1\u6a23\u4e0d\u8db3\u662f\u53e6\u4e00\u500b\u56b4\u91cd\u554f\u984c\u3002\u5927\u90e8\u5206\u751f\u7269\u6a19\u8a18\u7814\u7a76\u6848\u7684\u6aa2\u6e2c\u6a23\u672c\u6578\u5747\u4f4e\u65bc\u4e00\u767e\uff0c\u56e0\u6b64\u6c92\u6709\u8db3\u5920\u7684\u7d71\u8a08\u6aa2\u5b9a\u529b\uff0c\u4f86\u89e3\u91cb\u591a\u91cd\u751f\u7269\u6a19\u8a18\u8207\u67d0\u4e00\u7279\u5b9a\u60c5\u6cc1\u9593\u7684\u9ad8\u5ea6\u76f8\u95dc\u6027\u3002\u4f9d\u64da\u64ec\u5206\u6790\u7684\u751f\u7269\u6a19\u8a18\u6578\u91cf\uff0c\u53ef\u80fd\u8981\u53d6\u5f97\u4e0a\u767e\u751a\u6216\u4e0a\u5343\u500b\u7b26\u5408\u63a7\u5236\u689d\u4ef6\u7684\u75be\u75c5\u6a23\u672c\uff0c\u624d\u80fd\u7b26\u5408\u6cd5\u898f\u7684\u8981\u6c42\uff0c\u4e26\u5c55\u73fe\u5be6\u9a57\u5177\u81e8\u5e8a\u6216\u7d93\u6fdf\u6548\u76ca\u3002<\/p>\n<p><strong>\u7d55\u4f73\u904b\u4f5c<\/strong><\/p>\n<figure id=\"attachment_8197\" aria-describedby=\"caption-attachment-8197\" style=\"width: 323px\" class=\"wp-caption alignright\"><img decoding=\"async\" class=\"size-full wp-image-8197 \" title=\"onedrop\" alt=\"\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2011\/03\/onedrop.jpg\" width=\"323\" height=\"489\" \/><figcaption id=\"caption-attachment-8197\" class=\"wp-caption-text\">\u6ec4\u6d77\u4e00\u7c9f\uff1a\u5728\u76ee\u524d\u5927\u91cf\u7684\u751f\u7269\u6a19\u8a18\u4e2d\uff0c\u53ea\u6709\u5f88\u5c11\u7684\u751f\u7269\u6a19\u8a18\u53ef\u4ee5\u7528\u65bc\u81e8\u5e8a\u3002\uff08\u5716\uff0fNature\uff09<\/figcaption><\/figure>\n<p>\u8fd1\u4f86\u767c\u5c55\u8da8\u52e2\u8d70\u5411\u591a\u91cd\u751f\u7269\u6a19\u8a18\u6aa2\u9a57\uff08\u5373\u591a\u6a23\u5206\u6790 multiplex profiling\uff09\uff0c\u5e36\u52d5\u4e86\u9ad8\u901a\u91cf\u5206\u6790\u6280\u8853\u7684\u5275\u65b0\u767c\u5c55\uff0c\u4ee5\u53ca\u904b\u7528\u65bc\u57fa\u56e0\u3001\u86cb\u767d\u8cea\u3001RNA\u5206\u5b50\u53ca\u4ee3\u8b1d\u7269\u7684\u81ea\u52d5\u5e73\u884c\u5206\u6790\u3002\u4f46\u9664\u975e\u6709\u7d44\u7e54\u53ca\u7d93\u8cbb\u5236\u5ea6\u7684\u6539\u9769\uff0c\u4e26\u4e14\u8aaa\u670d\u7814\u7a76\u793e\u7fa4\u540c\u610f\u63a1\u7528\u5171\u540c\u6a19\u6e96\uff0c\u4ee5\u53ca\u8de8\u5b78\u79d1\u9818\u57df\u7684\u7cfb\u7d71\u6027\u7814\u7a76\u65b9\u6cd5\uff0c\u4f86\u9032\u884c\u751f\u7269\u6a19\u8a18\u641c\u5c0b\u8207\u9a57\u8b49\uff0c\u9019\u4e9b\u6280\u8853\u5275\u65b0\u4e26\u7121\u6cd5\u767c\u63ee\u529f\u6548\u3002<\/p>\n<p>\u5df2\u6709\u4eba\u5c55\u958b\u884c\u52d5\u6539\u9032\u4eba\u9ad4\u7d44\u7e54\u5132\u5b58\uff08\u4eba\u9ad4\u751f\u7269\u8cc7\u6599\u5eab\uff09\u7684\u904b\u4f5c\u65b9\u5f0f\u3002\u4f8b\u5982\u7f8e\u570b\u570b\u5bb6\u764c\u75c7\u7814\u7a76\u6240\u7684\u4eba\u985e\u764c\u75c7\u751f\u7269\u8cc7\u6599\u5eab\uff08caHUB\uff09 \uff0c\u5df2\u5efa\u7acb\u56b4\u683c\u7684\u898f\u7bc4\uff0c\u4ee5\u78ba\u4fdd\u4f86\u81ea\u5065\u5eb7\u500b\u4eba\u53ca\u764c\u75c7\u75c5\u60a3\u7684\u6a23\u672c\uff0c\u4f9d\u6a19\u6e96\u7a0b\u5e8f\u63a1\u6a23\u3001\u8a3b\u8a18\u3001\u5132\u5b58\u8207\u5206\u6790\uff0c\u4e26\u4e14\u9644\u6709\u6240\u9700\u7684\u6350\u8d08\u8005\u91ab\u7642\u8cc7\u8a0a\u3002\u5927\u81f4\u4e0a\u9019\u6a23\u7684\u904b\u4f5c\u65b9\u5f0f\u5df2\u70ba\u4eba\u9ad4\u751f\u7269\u8cc7\u6599\u5eab\u6a39\u7acb\u4e86\u300c\u6700\u4f73\u904b\u4f5c\u5178\u7bc4\u300d\u3002\u4f46\u70ba\u6c42\u5468\u5ef6\uff0c\u4ecd\u6709\u5fc5\u8981\u6210\u7acb\u570b\u969b\u4eba\u9ad4\u751f\u7269\u8cc7\u6599\u5eab\uff0c\u6b64\u90e8\u5206\u9700\u8981\u8a02\u5b9a\u570b\u969b\u901a\u7528\u6cd5\u898f\uff0c\u8b93\u5168\u7403\u5404\u5730\u7684\u7814\u7a76\u4eba\u54e1\u90fd\u6709\u6b0a\u4f7f\u7528\u8a72\u9805\u8cc7\u6e90\uff0c\u4e0d\u56e0\u4e0d\u76f8\u5bb9\u7684\u6a19\u6e96\u6216\u672a\u5354\u8abf\u7684\u6cd5\u898f\u969c\u7919\u800c\u53d7\u9650\u3002<\/p>\n<p>\u66f4\u91cd\u8981\u7684\u662f\uff0c\u7814\u7a76\u8cc7\u91d1\u63d0\u4f9b\u8005\uff0c\u4f8b\u5982\u7f8e\u570b\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662\u3001\u6b50\u76df\u79d1\u7814\u67b6\u69cb\u8a08\u756b\u3001\u6b50\u76df\u5275\u65b0\u91ab\u85e5\u7814\u7a76\u5148\u5c0e\u8a08\u756b\u53ca\u82f1\u570b\u885b\u723e\u5eb7\u4fe1\u8a17\u7b49\u55ae\u4f4d\uff0c\u61c9\u8a72\u8981\u6c42\u751f\u7269\u6a19\u8a18\u7814\u7a76\u6709\u8f03\u597d\u7684\u6295\u8cc7\u5831\u916c\u8868\u73fe\u3002\u60df\u6709\u7b26\u5408\u4e0b\u8ff0\u689d\u4ef6\u7684\u7814\u7a76\u8a08\u756b\u624d\u80fd\u7372\u5f97\u8cc7\u52a9\uff1a\u80fd\u53d6\u5f97\u8db3\u5920\u6578\u91cf\u4e14\u7279\u6027\u660e\u78ba\u7684\u6a23\u672c\uff1b\u6a23\u672c\u63a1\u96c6\u3001\u8655\u7406\u53ca\u5132\u5b58\u5747\u57f7\u884c\u56b4\u8b39\u7684\u54c1\u8cea\u63a7\u5236\u7a0b\u5e8f\uff1b\u64c1\u6709\u5b8c\u6574\u7684\u8de8\u9818\u57df\u5c08\u624d\uff0c\u80fd\u5c07\u5be6\u9a57\u5ba4\u7684\u767c\u73fe\u8f49\u8b6f\u70ba\u81e8\u5e8a\u7528\u9014\u3002\u5982\u6b64\u5c07\u9f13\u52f5\u5f9e\u4e8b\u5b78\u8853\u7814\u7a76\u7684\u5be6\u9a57\u5ba4\uff0c\u900f\u904e\u64f4\u5c55\u7684\u7814\u7a76\u7db2\u8def\uff0c\u52a0\u5f37\u548c\u91ab\u9662\u53ca\u7522\u696d\u754c\u7684\u5408\u4f5c\u3002<\/p>\n<p><strong>\u532f\u6ef4\u6210\u6d77<\/strong><\/p>\n<p>\u70ba\u9032\u884c\u591a\u6a23\u5206\u6790\u9a57\u8b49\uff0c\u5fc5\u9808\u63a1\u96c6\u5927\u6a23\u672c\u6578\uff0c\u56e0\u800c\u7522\u751f\u5927\u91cf\u8cc7\u6599\u96c6\u3002\u96a8\u8457\u5168\u57fa\u56e0\u9ad4\u5b9a\u5e8f\u5206\u6790\u7684\u666e\u53ca\uff0c\u76f8\u95dc\u8cc7\u6599\u96c6\u898f\u6a21\u5c07\u6301\u7e8c\u64f4\u5927\uff0c\u5fc5\u9808\u4ef0\u8cf4\u8cc7\u8a0a\u5b78\u5c08\u5bb6\u904b\u7528\u8907\u96dc\u7684\u6578\u5b78\u3001\u7d71\u8a08\u53ca\u8a08\u7b97\u6280\u80fd\u52a0\u4ee5\u5206\u6790\u3002\u91dd\u5c0d\u6b64\u7a2e\u5927\u898f\u6a21\u8a08\u756b\uff0c\u5fc5\u9808\u4ee5\u6a19\u6e96\u5316\u7a0b\u5e8f\u5c07\u8cc7\u6599\u7d00\u9304\u6210\u6587\u4ef6\u3001\u52a0\u4ee5\u5132\u5b58\u53ca\u9032\u884c\u5206\u6790\uff0c\u82e5\u8981\u5c07\u5019\u9078\u751f\u7269\u6a19\u8a18\u5f9e\u5b78\u8853\u7814\u7a76\u8f49\u5165\u81e8\u5e8a\u7528\u9014\uff0c\u5247\u5fc5\u9808\u548c\u7522\u696d\u754c\u8207\u4e3b\u7ba1\u6a5f\u95dc\u6240\u4f7f\u7528\u7684\u8cc7\u6599\u683c\u5f0f\u4ee5\u53ca\u7528\u4f86\u7522\u751f\u96fb\u5b50\u5316\u5065\u5eb7\u7d00\u9304\u7684\u8edf\u9ad4\uff0c\u5f7c\u6b64\u76f8\u5bb9\u3002\u70ba\u548c\u7522\u696d\u754c\u53ca\u91ab\u9662\u7d50\u76df\uff0c\u5c07\u4fc3\u4f7f\u5b78\u8853\u754c\u6a19\u6e96\u5316\u76f8\u95dc\u4f5c\u696d\u3002<\/p>\n<p>\u5019\u9078\u751f\u7269\u6a19\u8a18\u9032\u5165\u6602\u8cb4\u7684\u9a57\u8b49\u7a0b\u5e8f\uff0c\u7522\u696d\u754c\u5408\u4f5c\u4f19\u4f34\u7684\u91cd\u8981\u6027\u958b\u59cb\u986f\u73fe\uff0c\u4ed6\u5011\u53ef\u4ee5\u63d0\u4f9b\u8ca1\u52d9\u7684\u8cc7\u52a9\uff0c\u4e26\u63d0\u4f9b\u9032\u884c\u5927\u898f\u6a21\u5206\u6790\u5316\u9a57\u7522\u51fa\u3001\u81e8\u5e8a\u8a66\u9a57\u8a2d\u8a08\u3001\u8cc7\u6599\u5206\u6790\u53ca\u6cd5\u898f\u9075\u5faa\u7b49\u6240\u9700\u7684\u5c08\u9580\u77e5\u8b58\u6216\u6280\u8853\u3002\u4f8b\u5982\u70ba\u9032\u884c\u591a\u6a23\u5206\u6790\u9a57\u8b49\uff0c\u8a2d\u8a08\u751f\u7269\u6a19\u8a18\u9a57\u8b49\u6e2c\u8a66\u6642\uff0c\u5fc5\u9808\u6709\u719f\u6089\u6cd5\u898f\u7684\u5c08\u5bb6\u53c3\u8207\uff0c\u4ee5\u78ba\u5b9a\u7b26\u5408\u4e3b\u7ba1\u6a5f\u95dc\u7684\u8981\u6c42\u3002\u8fd1\u4f86\u6709\u4e00\u4e9b\u751f\u7269\u79d1\u6280\u516c\u53f8\u5728\u884c\u92b7\u75be\u75c5\u57fa\u56e0\u6aa2\u9a57\u670d\u52d9\u524d\uff0c\u672a\u5148\u5c31\u6aa2\u9a57\u8a02\u5b9a\u6a19\u6e96\u5316\u7a0b\u5e8f\uff0c\u6b63\u53cd\u6620\u51fa\u672a\u4e8b\u5148\u5fb5\u8a62\u5c08\u5bb6\u610f\u898b\u6240\u9762\u81e8\u7684\u5371\u96aa\u8207\u767c\u5c55\u969c\u7919\u3002<\/p>\n<p>\u9a57\u8b49\u904e\u7a0b\u4e5f\u9700\u8981\u5065\u5eb7\u7167\u8b77\u7d93\u6fdf\u5c08\u5bb6\u7684\u5354\u52a9\u3002\u73fe\u4eca\u5065\u5eb7\u7167\u8b77\u6108\u4f86\u6108\u5f37\u8abf\u6210\u672c\u6548\u76ca\uff0c\u7d93\u4e3b\u7ba1\u7576\u5c40\u6838\u51c6\u7684\u6848\u4ef6\u4e26\u4e0d\u4fdd\u8b49\u5fc5\u7372\u81e8\u5e8a\u63a1\u7528\u3002\u7814\u7a76\u4eba\u54e1\u5fc5\u9808\u8b49\u660e\uff0c\u5176\u8a3a\u65b7\u6aa2\u9a57\u80fd\u6539\u9032\u81e8\u5e8a\u8a3a\u7642\u4f5c\u70ba\uff0c\u4e26\u964d\u4f4e\u8cbb\u7528\uff0c\u6216\u662f\u80fd\u6539\u5584\u75c5\u4eba\u7684\u5065\u5eb7\uff0c\u6216\u662f\u80fd\u5920\u514d\u9664\u6602\u8cb4\u4e14\u7121\u6548\u7684\u6cbb\u7642\u3002<\/p>\n<p>\u5b78\u8853\u754c\u65e2\u6709\u7684\u7814\u7a76\u6587\u5316\u548c\u7d44\u7e54\uff0c\u4ee5\u53ca\u5206\u6790\u6280\u8853\u7684\u4e0d\u8db3\u7684\u554f\u984c\uff0c\u540c\u6a23\u8b93\u751f\u7269\u6a19\u8a18\u7814\u7a76\u7684\u767c\u5c55\u53d7\u963b\u3002\u70ba\u8b93\u751f\u7269\u6a19\u8a18\u7814\u7a76\u5177\u81e8\u5e8a\u5be6\u7528\u6027\uff0c\u5176\u904b\u4f5c\u6a21\u5f0f\uff0c\u61c9\u8a72\u53c3\u8003\u70ba\u570b\u969b\u5168\u57fa\u56e0\u7d44\u95dc\u806f\u6027\u7814\u7a76\u800c\u555f\u52d5\u7684\u5927\u898f\u6a21\u5408\u4f5c\u7db2\u8def\uff0c\u4ee5\u53ca\u7531\u8a31\u591a\u6a5f\u69cb\u5171\u540c\u53c3\u8207\u7814\u7a76\u5206\u6790\u7684\u7269\u7406\u3001\u6c23\u5019\u8b8a\u5316\u53ca\u5efa\u7acb\u8907\u96dc\u9ad4\u7cfb\u6a21\u578b\u7b49\u7684\u5927\u578b\u79d1\u5b78\u8a08\u756b\u3002<\/p>\n<p>\u751f\u7269\u6a19\u8a18\u6240\u5177\u6709\u6539\u9032\u8a3a\u7642\u53ca\u964d\u4f4e\u5065\u5eb7\u7167\u8b77\u6210\u672c\u7684\u6f5b\u5728\u5229\u76ca\uff0c\u6bd4\u7576\u4eca\u5176\u4ed6\u4efb\u4f55\u7684\u91ab\u5b78\u7814\u7a76\u90fd\u8981\u4f86\u5f97\u5927\u3002\u7814\u7a76\u751f\u7269\u6a19\u8a18\u7684\u8ad6\u6587\u5df2\u6709\u4e0a\u5343\u7bc7\uff0c\u904e\u53bb\u5341\u5e74\u4f86\u5168\u7403\u5c0d\u8a72\u9818\u57df\u7684\u516c\u5171\u6295\u8cc7\u6709\u6578\u5104\u7f8e\u91d1\uff0c\u4f46\u771f\u6b63\u7528\u65bc\u81e8\u5e8a\u8a3a\u7642\u7684\u751f\u7269\u6a19\u8a18\u6578\u91cf\u5f88\u5c11\u3002\u73fe\u5728\u8a72\u662f\u91cd\u65b0\u5efa\u69cb\u751f\u7269\u6a19\u8a18\u7814\u7a76\uff0c\u8457\u91cd\u5be6\u8cea\u63d0\u5347\u5065\u5eb7\u7167\u8b77\u54c1\u8cea\u7684\u6642\u5019\u4e86\u3002<\/p>\n<pre>\u672c\u6587\u70ba\u7f8e\u570b\u4e9e\u5229\u6851\u90a3\u5dde\u7acb\u5927\u5b78\u5065\u5eb7\u5275\u65b0\u6559\u6388\u53ca\u8907\u96dc\u9069\u61c9\u7cfb\u7d71\u8a08\u756b\u4e3b\u4efb\u79d1\u5b78\u5bb6\u6ce2\u65af\u7279\uff08George Poste\uff09\u5728\u4e8c\u25cb\u4e00\u4e00\u5e74\u4e00\u6708\u5341\u4e09\u65e5\u300a\u81ea\u7136\u300b\u96dc\u8a8c\u7684\u5c08\u6587<\/pre>\n<pre><span style=\"color: #333333;\">\u5ef6\u4f38\u95b1\u8b80\uff1a<\/span><a href=\"http:\/\/k-review.com.tw\/2007\/11\/01\/604\/\" target=\"_blank\"><span style=\"color: #333333;\">\u751f\u7269\u6a19\u8a18\u662f\u6297\u764c\u4ed9\u4e39\uff1f<\/span><\/a><span style=\"color: #333333;\">\uff08\u77e5\u8b58\u901a\u8a0a\u8a55\u8ad661\u671f\uff09<\/span><strong>\r\n<\/strong><\/pre>\n<p><span style=\"color: #800000;\"><strong><span style=\"color: #993300;\">\u539f\u8f09\u65bc\u3010<\/span><a href=\"http:\/\/www.k-review.com.tw\/index\/\" target=\"_blank\"><span style=\"color: #993300;\">\u77e5\u8b58\u901a\u8a0a\u8a55\u8ad6\u6708\u520a\u4e00\u767e\u671f<\/span><\/a><span style=\"color: #993300;\">\u30112011.02.01<\/span><\/strong><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0 \u4ee5\u751f\u7269\u6a19\u8a18\u4f86\u4f5c\u70ba\u75be\u75c5\u8a3a\u65b7\u95dc\u806f\u6307\u6a19\u7684\u7814<\/p>\n","protected":false},"author":20,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,26,1025],"tags":[668,2248,27],"aioseo_notices":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/8192"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8192"}],"version-history":[{"count":14,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/8192\/revisions"}],"predecessor-version":[{"id":16357,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/8192\/revisions\/16357"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8192"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8192"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8192"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}