{"id":6656,"date":"2010-12-14T13:52:14","date_gmt":"2010-12-14T05:52:14","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=6656"},"modified":"2017-03-31T23:20:50","modified_gmt":"2017-03-31T15:20:50","slug":"%e3%80%90%e7%b9%81%e6%ae%96%e5%a5%a7%e7%a7%98%e3%80%91%e4%b8%80%e7%aa%a9%e5%b0%8f%e9%bc%a0%e5%85%a9%e5%80%8b%e7%88%b8","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=6656","title":{"rendered":"\u3010\u751f\u547d\u79d1\u5b78\u3011\u4e00\u7aa9\u5c0f\u9f20\u5169\u500b\u7238"},"content":{"rendered":"<p><span style=\"color: #800000;\"><strong>\u25a0 \u900f\u904e\u57fa\u56e0\u91cd\u7de8\u7a0b\u6280\u8853\uff0c\u53ef\u4ee5\u8b93\u5c0f\u9f20\u7e41\u884d\u51fa\u4f86\u50c5\u81ea\u5169\u540d\u96c4\u6027\u8840\u7de3\u7684\u5f8c\u4ee3\uff0c\u4ea6\u5373\u7537\u7537\u751f\u6b96\u7406\u8ad6\u4e0a\u4e26\u975e\u4e0d\u53ef\u884c\u3002\u4e0d\u904e\u9019\u6a23\u7684\u5617\u8a66\u986f\u7136\u9084\u4e0d\u592a\u53ef\u80fd\u7528\u5728\u4e00\u822c\u54fa\u4e73\u985e\u52d5\u7269\u8eab\u4e0a\u2014\u6709\u502b\u7406\u722d\u8b70\uff0c\u800c\u4e14\u592a\u5371\u96aa\u3002<\/strong><\/span><\/p>\n<figure id=\"attachment_6658\" aria-describedby=\"caption-attachment-6658\" style=\"width: 640px\" class=\"wp-caption alignnone\"><a href=\"http:\/\/www.flickr.com\/photos\/e3000\/99786620\/lightbox\/\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-6658 \" title=\"e3\u00b0\u00b0\u00b0@flickr\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2010\/12\/e3\u00b0\u00b0\u00b0@flickr.jpg\" alt=\"\" width=\"640\" height=\"491\" \/><\/a><figcaption id=\"caption-attachment-6658\" class=\"wp-caption-text\">\u300c\u7121\u7236\u4f55\u6019\uff0c\u7121\u6bcd\u4f55\u6043\u300d\uff0c\u6211\u662f\u5c0f\u9f20\uff0c\u6240\u4ee5\u4e0d\u6015\uff01<\/figcaption><\/figure>\n<p><strong>\u7de8\u8b6f <\/strong>\u2223 Gerda<\/p>\n<p>\u3000\u3000\u79d1\u5b78\u5bb6\u6700\u8fd1\u6709\u500b\u8a6d\u7570\u7684\u58ef\u8209\uff0c\u4ee5\u5169\u96bb\u516c\u9f20\u7684\u57fa\u56e0\u88fd\u9020\u51fa\u4e00\u7aa9\u65b0\u751f\u5c0f\u9f20\u3002\u7c21\u55ae\u8aaa\uff0c\u9019\u7fa4\u5c0f\u9f20\u81ea\u5e7c\u5931\u6043\uff0c\u5929\u751f\u6c92\u6709\u5abd\u3002<\/p>\n<p>\u3000\u3000\u9019\u9805\u7814\u7a7612\u67088\u65e5\u520a\u8f09\u65bc\u300a\u7e41\u6b96\u751f\u7269\u5b78\u300b\uff08<em>Biology of Reproduction<\/em>\uff09\u4e0a\uff0c\u85c9\u8457\u53ea\u5177\u6709\u7236\u7cfb\u67d3\u8272\u9ad4\u7684\u5375\u5b50\uff0c\u52a0\u4e0a\u53e6\u4e00\u96bb\u96c4\u9f20\u7684\u57fa\u56e0\uff0c\u5f97\u51fa\u6b64\u4e00\u7d50\u679c\u3002<\/p>\n<p>\u3000\u3000\u7f8e\u570b\u5fb7\u5dde\u5927\u5b78\u7684\u907a\u50b3\u5b78\u8005\u8c9d\u9748\u5091\uff08Richard Behringer\uff09\u8aaa\uff0c\u9019\u65b0\u5947\u7684\u7814\u7a76\u5c0d\u65bc\u54fa\u4e73\u985e\u52d5\u7269\u7e41\u6b96\u4ee5\u53ca\u8f14\u52a9\u7e41\u6b96\u6280\u8853\u5bd3\u610f\u6df1\u9060\u3002<\/p>\n<p>\u3000\u3000\u7e7c\u5229\u7528\u4f86\u81ea<a href=\"http:\/\/www.wired.com\/wiredscience\/2010\/04\/mitochondria-engineering\" target=\"_blank\">\u4e09\u4eba\u7684DNA\u5275\u9020\u4eba\u985e\u80da\u80ce<\/a>\uff0c\u53ca\u4ee5\u5169\u96bb\u6bcd\u7334\u7684\u57fa\u56e0\u8907\u88fd\u7334\u5b50\u4e4b\u5f8c\uff0c\u300c\u96d9\u7239\u5c0f\u9f20\u300d\u7814\u7a76\u518d\u5275\u65b0\u5c40\u3002\u9019\u4e9b\u6280\u8853\u96e2\u5be6\u969b\u904b\u7528\u5728\u4eba\u985e\u8eab\u4e0a\u9084\u65e9\u5f97\u5f88\uff0c\u751a\u81f3\u53ef\u80fd\u6c38\u9060\u4e0d\u6703\u6709\u5408\u6cd5\u7684\u4e00\u5929\u3002\u4e0d\u904e\u5c0d\u65bc\u907f\u514d\u67d0\u4e9b\u91cd\u5927\u907a\u50b3\u7f3a\u9677\u4ee3\u4ee3\u50b3\u905e\uff0c\u53ef\u80fd\u6703\u6709\u5e6b\u52a9\u3002<\/p>\n<p><!--more--><\/p>\n<p>\u3000\u3000\u540c\u6a23\u7684\uff0c\u300c\u96d9\u7239\u5c0f\u9f20\u300d\u6280\u8853\u63d0\u4f9b\u4e86\u7406\u8ad6\u4e0a\u80fd\u5920\u907f\u514d\u7c92\u817a\u9ad4\u75be\u75c5\uff08mitochondrial disease\uff09\u7684\u65b9\u6cd5\uff0c\u5118\u7ba1\u5be6\u969b\u64cd\u4f5c\u8207\u9053\u5fb7\u502b\u7406\u5c64\u9762\u90fd\u9084\u554f\u984c\u91cd\u91cd\u3002\u6216\u8a31\u904b\u7528\u5728\u80b2\u7a2e\u4ee5\u53ca\u62ef\u6551\u7015\u5371\u52d5\u7269\u9084\u6bd4\u8f03\u53ef\u884c\u4e00\u4e9b\u3002<\/p>\n<figure id=\"attachment_6661\" aria-describedby=\"caption-attachment-6661\" style=\"width: 484px\" class=\"wp-caption alignright\"><a rel=\"attachment wp-att-6661\" href=\"http:\/\/case.ntu.edu.tw\/blog\/?attachment_id=6661\" target=\"_blank\"><img decoding=\"async\" class=\"size-full wp-image-6661\" title=\"mouse_2_dad\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2010\/12\/mouse_2_dad.png\" alt=\"\" width=\"484\" height=\"322\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2010\/12\/mouse_2_dad.png 605w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2010\/12\/mouse_2_dad-600x399.png 600w\" sizes=\"(max-width: 484px) 100vw, 484px\" \/><\/a><figcaption id=\"caption-attachment-6661\" class=\"wp-caption-text\">\u5716\u89e3\u96d9\u7239\u5c0f\u9f20\u7684\u64cd\u4f5c\u904e\u7a0b\u3002\uff08\u5716\u7247\u4f86\u6e90\uff1a\u7e41\u6b96\u751f\u7269\u5b78\u671f\u520a\uff09<\/figcaption><\/figure>\n<p><strong>\u7e41\u884d\u96d9\u7239\u5c0f\u9f20<\/strong><\/p>\n<p>\u3000\u3000\u7814\u7a76\u8005\u5f9e\u96c4\u6027\u5c0f\u9f20\uff08\u53ef\u7a31\u70ba\u7238\u7238\u4e00\u865f\uff09\u8eab\u4e0a\u57f9\u990a\u4e00\u4e9b\u4eba\u5de5\u591a\u80fd\u5e79\u7d30\u80de\uff08<a href=\"http:\/\/ja.wikipedia.org\/wiki\/%E4%BA%BA%E5%B7%A5%E5%A4%9A%E8%83%BD%E6%80%A7%E5%B9%B9%E7%B4%B0%E8%83%9E\" target=\"_blank\">Induced pluripotent stem cells, iPS<\/a>\uff09\uff0ciPS\u65bc2000\u5e74\u7531\u65e5\u672c\u4eac\u90fd\u5927\u5b78\u5b78\u8005\u5c71\u4e2d\u4f38\u5f4c\u7b49\u4eba\u7814\u767c\u6210\u529f\uff0c\u662f\u4e00\u7a2e\u900f\u904e\u57fa\u56e0\u91cd\u7de8\u7a0b\uff08reprogramming\uff09\u800c\u8fd1\u4f3c\u5e79\u7d30\u80de\u72c0\u614b\u7684\u7d30\u80de\u3002\u7d04\u6709\u767e\u5206\u4e4b\u4e00\u7684iPS\u7d30\u80de\u5728\u5206\u5316\u6642\u6703\u81ea\u52d5\u5931\u53bbY\u67d3\u8272\u9ad4\uff0c\u8b8a\u6210XO\u7d30\u80de\uff08X-only cells\uff09\u3002<\/p>\n<p>\u3000\u3000\u63a5\u8457XO\u7d30\u80de\u7684DNA\u88ab\u53d6\u51fa\u4f86\uff0c\u6ce8\u5165\u672a\u6210\u719f\u7684\u80da\u80ce\u88e1\uff0c\u6b96\u5165\u4ee3\u7406\u5b55\u6bcd\u9ad4\u5167\u3002\u5982\u6b64\u7522\u751f\u7684\u5f8c\u4ee3\u5177\u6709\u4f86\u81ea\u7236\u7cfb\u7684X\u67d3\u8272\u9ad4\uff0c\u4e14\u5176\u4e2d\u90e8\u5206\u96cc\u6027\u5c0f\u9f20\u7684\u5375\u53ea\u5177\u6709\u7238\u7238\u4e00\u865f\u7684\u67d3\u8272\u9ad4\u3002<\/p>\n<p>\u3000\u3000\u9019\u4e9b\u5c0f\u9f20\u9577\u5927\u4e4b\u5f8c\uff0c\u8207\u5176\u4ed6\u96c4\u9f20\u4ea4\u914d\uff08\u5c31\u662f\u7238\u7238\u4e8c\u865f\uff09\uff0c\u5c31\u6703\u751f\u7522\u51fa\u5168\u90e8\u4f86\u81ea\u7236\u7cfb\u57fa\u56e0\u7684\u5c0f\u9f20\u3002<\/p>\n<p>\u3000\u3000\u9019\u9805\u6280\u8853\u6709\u500b\u91cd\u5927\u7f3a\u9677\uff0c\u90a3\u5c31\u662f\u91cd\u7de8\u7a0b\u5f8c\u7684\u7d30\u80de\u50be\u5411\u65bc\u8f49\u8b8a\u6210\u764c\u7d30\u80de\u3002\u7814\u7a76\u8005\u8868\u793a\uff0c\u82e5\u5148\u4e0d\u7ba1\u9019\u500b\u56b4\u91cd\u7f3a\u9677\uff0c\u5229\u7528\u91cd\u7de8\u7a0b\u6280\u8853\u4f86\u300c\u8b93\u5973\u6027\u6350\u8d08\u8005\u7522\u751f\u7cbe\u5b50\u300d\u3001\u300c\u4ee4\u5169\u500b\u6bcd\u89aa\u751f\u7522\u51fa\u5f97\u4ee5\u5b58\u6d3b\u7684\u7537\u5973\u5f8c\u4ee3\u300d\u90fd\u662f\u6709\u53ef\u80fd\u7684\u3002<\/p>\n<p>\u3000<\/p>\n<pre><span style=\"color: #333333;\">\u539f\u6587\u51fa\u8655\uff1a<\/span><a href=\"http:\/\/www.biolreprod.org\/content\/early\/2010\/12\/07\/biolreprod.110.088831.abstract\" target=\"_blank\"><span style=\"color: #333333;\">Generation of Viable Male and Female Mice from Two Fathers (<em>Biology of Reproduction<\/em>, December 8, 2010)<\/span><\/a><\/pre>\n<p><span style=\"color: #003366;\"><strong>\u8cac\u4efb\u7de8\u8f2f\uff1aMissZoe<\/strong><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0 \u900f\u904e\u57fa\u56e0\u91cd\u7de8\u7a0b\u6280\u8853\uff0c\u53ef\u4ee5\u8b93\u5c0f\u9f20\u7e41\u884d\u51fa<\/p>\n","protected":false},"author":20,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21,3293],"tags":[129,174,601],"aioseo_notices":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/6656"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6656"}],"version-history":[{"count":32,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/6656\/revisions"}],"predecessor-version":[{"id":6993,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/6656\/revisions\/6993"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6656"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6656"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6656"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}