{"id":46330,"date":"2026-04-23T17:00:01","date_gmt":"2026-04-23T09:00:01","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=46330"},"modified":"2026-04-23T17:05:06","modified_gmt":"2026-04-23T09:05:06","slug":"%e5%99%a8%e5%ae%98%e6%99%b6%e7%89%87%ef%bc%9a%e5%9c%a8%e5%be%ae%e5%9e%8b%e4%ba%ba%e9%ab%94%e4%b8%ad%ef%bc%8c%e9%a0%90%e8%a6%8b%e6%96%b0%e8%97%a5%e7%9a%84%e6%9c%aa%e4%be%86","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=46330","title":{"rendered":"\u5668\u5b98\u6676\u7247\uff1a\u5728\u5fae\u578b\u4eba\u9ad4\u4e2d\uff0c\u9810\u898b\u65b0\u85e5\u7684\u672a\u4f86"},"content":{"rendered":"

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\u64b0\u6587\uff5c\u6797\u6cf3\u4ea8<\/strong><\/p>\n

\u65b0\u85e5\u958b\u767c\u7684\u56f0\u5883\uff1a\u52d5\u7269\u6a21\u578b\u7684\u6975\u9650<\/strong><\/span><\/h6>\n

\u5728\u73fe\u4ee3\u91ab\u5b78\u4e2d\uff0c\u5118\u7ba1\u5168\u7403\u7684\u88fd\u85e5\u516c\u53f8\u8207\u7814\u7a76\u6a5f\u69cb\u6bcf\u5e74\u6295\u5165\u6578\u5341\u5104\u7f8e\u5143\u7684\u7d93\u8cbb\u548c\u6578\u5341\u5e74\u7684\u7814\u767c\u6642\u9593\uff0c\u4f46\u5728\u6bcf\u5341\u7a2e\u6210\u529f\u901a\u904e\u52d5\u7269\u6e2c\u8a66\u7684\u5019\u9078\u85e5\u7269\u4e2d\uff0c\u4ecd\u6709\u9ad8\u9054\u4e5d\u7a2e\uff0c\u6703\u5728\u6700\u7d42\u7684\u4eba\u9ad4\u81e8\u5e8a\u8a66\u9a57\u4e2d\u4ee5\u5931\u6557\u544a\u7d42\u3002\u5728\u9019\u4e9b\u5931\u6557\u4e2d\uff0c\u7d04\u6709\u516d\u6210\u6e90\u65bc\u85e5\u7269\u5728\u4eba\u9ad4\u4e0a\u7121\u6cd5\u5c55\u73fe\u9810\u671f\u7684\u7642\u6548\uff0c\u53e6\u6709\u4e09\u6210\u5247\u662f\u56e0\u70ba\u51fa\u73fe\u4e86\u7121\u6cd5\u63a7\u5236\u7684\u56b4\u91cd\u6bd2\u6027\u3002\u9019\u6a23\u7684\u5931\u6557\u7387\uff0c\u4e0d\u50c5\u662f\u91d1\u9322\u7684\u5de8\u5927\u6d6a\u8cbb\uff0c\u66f4\u610f\u5473\u8457\u7121\u6578\u60a3\u8005\u7684\u7b49\u5f85\u843d\u7a7a\u3002\u8a72\u7d50\u679c\u8aaa\u660e\u4e86\u4e00\u500b\u554f\u984c\uff1a\u6578\u5341\u5e74\u4f86\u7814\u7a76\u6240\u4f9d\u8cf4\u7684\u52d5\u7269\u6a21\u578b\uff0c\u7d42\u7a76\u7121\u6cd5\u5b8c\u5168\u9810\u6e2c\u4eba\u985e\u7684\u751f\u7406\u53cd\u61c9\u3002\u7f85\u975e\u6614\u5e03 (Vioxx) \u662f\u4e00\u6b3e\u66fe\u88ab\u5bc4\u4e88\u539a\u671b\u7684\u6b62\u75db\u85e5\uff0c\u5b83\u5728\u591a\u9054\u4e5d\u9805\u91dd\u5c0d\u5c0f\u9f20\u548c\u5927\u9f20\u7684\u52d5\u7269\u7814\u7a76\u4e2d\u5747\u986f\u793a\u5c0d\u5fc3\u8840\u7ba1\u7cfb\u7d71\u5b89\u5168\uff0c\u751a\u81f3\u5728\u5176\u4e2d\u516d\u9805\u7814\u7a76\u4e2d\u88ab\u767c\u73fe\u5177\u6709\u5fc3\u81df\u4fdd\u8b77\u4f5c\u7528\u3002\u7136\u800c\uff0c\u7576\u5b83\u88ab\u5ee3\u6cdb\u61c9\u7528\u65bc\u4eba\u985e\u5f8c\uff0c\u537b\u5728\u5168\u7403\u9020\u6210\u4e86\u4f30\u8a08\u9ad8\u905414\u842c\u4f8b\u81f4\u547d\u7684\u5fc3\u81df\u75c5\u767c\u4f5c\u548c\u4e2d\u98a8\uff0c\u6700\u7d42\u57282004\u5e74\u88ab\u5168\u9762\u64a4\u5e02\u3002<\/p>\n

\u9664\u4e86\u6e96\u78ba\u5ea6\u7684\u7f3a\u9677\u5916\uff0c\u52d5\u7269\u5be6\u9a57\u7684\u8ca0\u64d4\u4e5f\u6975\u5176\u6c89\u91cd\u3002\u6839\u64da\u6b50\u6d32\u7684\u6578\u64da\uff0c\u4e00\u9805\u91cd\u8907\u7d66\u85e5\u7684\u6bd2\u7406\u8a66\u9a57\u6210\u672c\u7d04\u70ba49,390\u6b50\u5143\uff0c\u800c\u958b\u767c\u55ae\u4e00\u7684\u55ae\u682a\u6297\u9ad4\u85e5\u7269\uff0c\u5e73\u5747\u9700\u8981\u6295\u5165\u4e5d\u5e74\u6642\u9593\u8207\u9ad8\u90546.5\u81f37.5\u5104\u7f8e\u5143\u7684\u7d93\u8cbb\u3002\u8fd1\u5e74\u4f86\uff0c\u975e\u4eba\u985e\u9748\u9577\u985e\u52d5\u7269\u7684\u5be6\u9a57\u6210\u672c\u66f4\u662f\u98c6\u5347\u81f3\u6bcf\u96bb5\u842c\u7f8e\u5143\uff0c\u4f7f\u7814\u767c\u8ca0\u64d4\u96ea\u4e0a\u52a0\u971c\u3002\u8207\u6b64\u540c\u6642\uff0c\u502b\u7406\u7684\u8003\u91cf\u4e5f\u65e5\u76ca\u9ad8\u6f32\u3002\u570b\u969b\u9593\u5021\u5c0e\u7684\u300c3R\u300d\u539f\u5247\u2014\u2014\u66ff\u4ee3 (Replacement)\u3001\u6e1b\u5c11 (Reduction) \u8207\u6539\u9032 (Refinement) \u5df2\u9010\u6f38\u5f9e\u5b78\u8853\u547c\u7c72\u8f49\u8b8a\u70ba\u5404\u570b\u7684\u5f37\u5236\u6cd5\u898f\u3002\u9019\u80a1\u58d3\u529b\u6b63\u5f9e\u5b78\u8853\u754c\u5ef6\u4f38\u81f3\u76e3\u7ba1\u6a5f\u69cb\uff0c\u7f8e\u570b\u98df\u54c1\u85e5\u7269\u7ba1\u7406\u5c40 (FDA) \u5df2\u5728\u51762025\u5e74\u7684\u8def\u7dda\u5716\u4e2d\u660e\u78ba\u63d0\u51fa\u76ee\u6a19\uff1a\u5e0c\u671b\u5728\u672a\u4f86\u4e09\u5230\u4e94\u5e74\u5167\uff0c\u8b93\u52d5\u7269\u7814\u7a76\u5f9e\u81e8\u5e8a\u524d\u6e2c\u8a66\u7684\u300c\u5e38\u898f\u300d\u8f49\u8b8a\u70ba\u300c\u4f8b\u5916\u300d\u3002\u9019\u9805\u5ba3\u793a\uff0c\u70ba\u66ff\u4ee3\u6280\u8853\u7684\u767c\u5c55\u63d0\u4f9b\u4e86\u524d\u6240\u672a\u6709\u7684\u5f37\u5927\u653f\u7b56\u63a8\u529b\u3002<\/p>\n

 <\/p>\n

\u6280\u8853\u7684\u8a95\u751f\uff1a\u5668\u5b98\u6676\u7247\u5982\u4f55\u91cd\u73fe\u4eba\u9ad4\u5fae\u74b0\u5883<\/span><\/strong><\/h6>\n

\u6b63\u662f\u5728\u9019\u500b\u8feb\u5207\u9700\u8981\u8b8a\u9769\u7684\u6642\u9593\u9ede\uff0c\u5668\u5b98\u6676\u7247 (Organ-on-Chip) \u6280\u8853\u61c9\u904b\u800c\u751f\uff0c\u63d0\u4f9b\u4e86\u4e00\u500b\u9769\u547d\u6027\u7684\u89e3\u6c7a\u65b9\u6848\u3002\u9019\u662f\u4e00\u9805\u7d50\u5408\u5fae\u6d41\u9ad4\u5de5\u7a0b\u8207\u7d30\u80de\u751f\u7269\u5b78\u7684\u6280\u8853\uff0c\u5176\u6838\u5fc3\u76ee\u6a19\u662f\uff0c\u5728\u4e00\u500b\u9ad4\u7a4d\u5f88\u5c0f\u7684\u6676\u7247\u4e0a\uff0c\u91cd\u5efa\u4e00\u500b\u5fae\u578b\u3001\u537b\u529f\u80fd\u5b8c\u5099\u7684\u4eba\u9ad4\u5668\u5b98\u3002\u9019\u4e9b\u6676\u7247\u901a\u5e38\u7531\u900f\u660e\u805a\u5408\u7269\u88fd\u6210\uff0c\u5167\u90e8\u5229\u7528\u5fae\u52a0\u5de5\u6280\u8853\uff0c\u8755\u523b\u51fa\u6bd4\u9aee\u7d72\u66f4\u7d30\u7684\u5fae\u6d41\u9ad4\u901a\u9053\u8207\u7d30\u80de\u8154\u5ba4\u3002\u79d1\u5b78\u5bb6\u6703\u5728\u9019\u4e9b\u8154\u5ba4\u4e2d\u57f9\u990a\u4eba\u985e\u4f86\u6e90\u7684\u7d30\u80de\uff0c\u4f86\u6e90\u53ef\u80fd\u662f\u75c5\u60a3\u7684\u539f\u751f\u7d30\u80de\uff0c\u4e5f\u53ef\u80fd\u662f\u7531\u8a98\u5c0e\u6027\u591a\u80fd\u5e79\u7d30\u80de (iPSC) \u5206\u5316\u51fa\u7684\u7279\u5b9a\u5668\u5b98\u7d30\u80de\u3002<\/p>\n

\u5668\u5b98\u6676\u7247\u8207\u50b3\u7d71\u7d30\u80de\u57f9\u990a\u7684\u6839\u672c\u5340\u5225\uff0c\u5728\u65bc\u5b83\u91cd\u73fe\u4e86\u4eba\u9ad4\u5167\u81f3\u95dc\u91cd\u8981\u7684\u300c\u52d5\u614b\u5fae\u74b0\u5883\u300d\u3002\u50b3\u7d71\u76842D\u57f9\u990a\u662f\u4f7f\u7d30\u80de\u5728\u4e00\u500b\u5e73\u9762\u975c\u614b\u751f\u9577\uff0c\u96e3\u4ee5\u9ad4\u73fe\u5728\u9ad4\u5167\u7684\u52d5\u614b\u74b0\u5883\u3002\u7136\u800c\uff0c\u5668\u5b98\u6676\u7247\u900f\u904e\u5fae\u6d41\u9ad4\u901a\u9053\uff0c\u6a21\u64ec\u4e86\u8840\u6db2\u5728\u5fae\u8840\u7ba1\u4e2d\u7684\u6301\u7e8c\u6d41\u52d5\u4ee5\u53ca\u8840\u6db2\u8207\u7d30\u80de\u7684\u4ea4\u4e92\u4f5c\u7528\u3002\u9019\u80a1\u6d41\u52d5\u4e0d\u50c5\u5e36\u4f86\u4e86\u990a\u5206\u3001\u79fb\u9664\u4e86\u5ee2\u7269\uff0c\u66f4\u5c0d\u7d30\u80de\u65bd\u52a0\u4e86\u7cbe\u78ba\u7684\u6d41\u9ad4\u526a\u5207\u529b (Fluid Shear Stress)\u3002\u9019\u7a2e3D\u7684\u985e\u7d44\u7e54\u7d50\u69cb\u3001\u52d5\u614b\u7684\u6db2\u9ad4\u4ea4\u63db\u3001\u4ee5\u53ca\u591a\u7d30\u80de\u7684\u7a7a\u9593\u6392\u5217\uff0c\u4f7f\u5f97\u7d30\u80de\u80fd\u5920\u5728\u4e00\u500b\u66f4\u63a5\u8fd1\u9ad4\u5167\u7684\u74b0\u5883\u4e0b\u5b58\u6d3b\u6578\u9031\u751a\u81f3\u6578\u6708\uff0c\u4e26\u7dad\u6301\u5176\u9ad8\u5ea6\u5206\u5316\u7684\u8907\u96dc\u529f\u80fd\uff0c\u4f8b\u5982\u809d\u81df\u7684\u4ee3\u8b1d\u3001\u814e\u81df\u7684\u904e\u6ffe\u6216\u5fc3\u81df\u7684\u8df3\u52d5\u3002<\/p>\n

\"\"
\u57161\uff1a\u5668\u5b98\u6676\u7247\u6280\u8853\u7684\u69cb\u6210\u6d41\u7a0b\uff1a\u7531\u4eba\u9ad4\u53d6\u5f97\u7d30\u80de\uff0c\u9032\u884c\u57f9\u990a\u5f8c\u7f6e\u5165\u5fae\u6d41\u9ad4\u6676\u7247\u4e2d\uff0c\u6700\u7d42\u53ef\u9023\u7d50\u591a\u500b\u5668\u5b98\u6a21\u578b\u5f62\u6210\u591a\u5668\u5b98\u7cfb\u7d71\uff5c\u4f86\u6e90\uff1a\u4f5c\u8005\u65bchttps:\/\/BioRender.com<\/a>\u7e6a\u88fd<\/figcaption><\/figure>\n

 <\/p>\n

\u5668\u5b98\u7684\u52d5\u529b\u5b78\uff1a\u6a21\u64ec\u547c\u5438\u8207\u8815\u52d5\u7684\u95dc\u9375\u7a81\u7834<\/span><\/strong><\/h6>\n

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\"\"
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 <\/p>\n

\u91cd\u5efa\u591a\u7d30\u80de\u4e92\u52d5\uff1a\u7570\u8cea\u6027\u8207\u529f\u80fd\u6027\u7684\u63d0\u5347<\/strong><\/span><\/h6>\n

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\u809d\u81df\u662f\u4eba\u9ad4\u7684\u89e3\u6bd2\u4e2d\u5fc3\uff0c\u7d55\u5927\u591a\u6578\u85e5\u7269\u90fd\u5728\u6b64\u8655\u4ee3\u8b1d\u3002\u50b3\u7d712D\u57f9\u990a\u7684\u809d\u7d30\u80de\u6703\u8fc5\u901f\u5931\u53bb\u5176\u4ee3\u8b1d\u9175\u7d20\u6d3b\u6027\uff0c\u4f7f\u5176\u7121\u6cd5\u7528\u65bc\u85e5\u7269\u6bd2\u6027\u6216\u4ee3\u8b1d\u7814\u7a76\u3002\u7136\u800c\uff0c\u5728\u5fae\u6d41\u9ad4\u704c\u6d41\u7684\u809d\u6676\u7247\u4e0a\uff0c\u9019\u4e9b\u7d30\u80de\u7684\u4ee3\u8b1d\u9175\u7d20\u6d3b\u6027\u5f97\u4ee5\u9577\u671f\u7dad\u6301\u30022022\u5e74\u767c\u8868\u65bc\u300aCommunications Medicine<\/em>\u300b\u7684\u4e00\u9805\u6307\u6a19\u6027\u9a57\u8b49\u4e2d\uff0cEmulate\u516c\u53f8\u7684\u809d\u81df\u6676\u7247\u88ab\u7528\u4f86\u6e2c\u8a66\u4e00\u7cfb\u5217\u5df2\u77e5\u85e5\u7269\uff0c\u7d50\u679c\u986f\u793a\uff0c\u5b83\u80fd\u6b63\u78ba\u8b58\u5225\u6703\u5c0d\u4eba\u985e\u9020\u6210\u809d\u640d\u50b7\u7684\u85e5\u7269\u3002\u9019\u4e9b\u6210\u679c\u986f\u793a\uff0c\u809d\u81df\u6676\u7247\u5df2\u5177\u5099\u8db3\u4ee5\u88dc\u8db3\u50b3\u7d71\u6a21\u578b\u4e0d\u8db3\u7684\u9810\u6e2c\u80fd\u529b\uff0c\u4e26\u6b63\u9010\u6f38\u6210\u70ba\u8a55\u4f30\u85e5\u7269\u5b89\u5168\u6027\u7684\u53ef\u9760\u5de5\u5177\u3002<\/p>\n

 <\/p>\n

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\u5668\u5b98\u6676\u7247\u7684\u80fd\u529b\u9084\u5728\u4e0d\u65b7\u64f4\u5c55\u3002\u79d1\u5b78\u5bb6\u5011\u5df2\u958b\u59cb\u6574\u5408\u5fae\u578b\u751f\u7269\u611f\u6e2c\u5668\uff0c\u6253\u9020\u5177\u5099\u5373\u6642\u76e3\u6e2c\u80fd\u529b\u7684\u667a\u6167\u6676\u7247\u3002\u4e00\u7bc72017\u5e74\u767c\u8868\u65bc\u300aPNAS<\/em>\u300b\u7684\u7814\u7a76\uff0c\u5c55\u793a\u4e86\u4e00\u500b\u5b8c\u5168\u6574\u5408\u7684\u6a21\u7d44\u5316\u5e73\u81fa\uff0c\u6676\u7247\u4e0a\u4e0d\u50c5\u6709\u63a7\u5236\u6d41\u9ad4\u7684\u5fae\u63a7\u5236\u5668\uff0c\u9084\u5167\u5efa\u4e86\u76e3\u6e2cpH\u3001\u6c27\u6c23\u3001\u6eab\u5ea6\u7684\u7269\u7406\u611f\u6e2c\u5668\u548c\u53ef\u9023\u7e8c\u539f\u4f4d\u76e3\u6e2c\u7d30\u80de\u5206\u6ccc\u7684\u751f\u7269\u6a19\u8a18\u7684\u96fb\u5316\u5b78\u611f\u6e2c\u5668\u3002\u8a72\u9ad8\u901a\u91cf\u5e73\u81fa\u751a\u81f3\u80fd\u6574\u5408\u7368\u7acb\u7684\u5fae\u578b\u5e6b\u6d66\u8207\u7d93\u4e0a\u76ae\u96fb\u963b (TEER) \u611f\u6e2c\u5668\uff0c\u8b93\u7814\u7a76\u4eba\u54e1\u80fd\u5be6\u6642\u8ffd\u8e64\u8178\u9053\u6216\u8840\u8166\u5c4f\u969c\u7684\u5b8c\u6574\u6027\u8b8a\u5316\u3002<\/p>\n

\"\"
\u57163\uff1a\u5c07\u5668\u5b98\u6676\u7247\u8207\u611f\u6e2c\u5668\u7d50\u5408\u5f8c\uff0c\u66f4\u80fd\u5be6\u6642\u8ffd\u8e64\u6676\u7247\u5167\u90e8\u7684\u72c0\u614b\u8b8a\u5316\uff5c\u4f86\u6e90\uff1a\u53c3\u8003\u6587\u737b12<\/figcaption><\/figure>\n

\u7576\u9019\u4e9b\u7368\u7acb\u7684\u5668\u5b98\u6676\u7247\u88ab\u4e32\u806f\u8d77\u4f86\uff0c\u4e00\u500b\u66f4\u5b8f\u5927\u7684\u6982\u5ff5\u2014\u2014\u300c\u591a\u5668\u5b98\u6676\u7247\u300d\u3002\u4f8b\u5982\uff0c\u4e00\u500b\u300c\u8178\uff0d\u809d\u6676\u7247\u300d\u7cfb\u7d71\u53ef\u4ee5\u7cbe\u78ba\u6a21\u64ec\u53e3\u670d\u85e5\u7269\u7684\u5b8c\u6574\u65c5\u7a0b\uff1a\u85e5\u7269\u9996\u5148\u5728\u8178\u9053\u6676\u7247\u88ab\u5438\u6536\uff0c\u5176\u5438\u6536\u7684\u5291\u91cf\u8207\u4ee3\u8b1d\u7269\uff0c\u96a8\u5f8c\u7d93\u7531\u5fae\u6d41\u9ad4\u901a\u9053\u9001\u5165\u809d\u81df\u6676\u7247\u9032\u884c\u5faa\u524d\u4ee3\u8b1d (presystemic metabolism)\u3002\u7814\u7a76\u8005\u56e0\u6b64\u80fd\u7cbe\u78ba\u8a55\u4f30\u85e5\u7269\u7684\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\uff0c\u4ee5\u53ca\u4ee3\u8b1d\u7269\u53ef\u80fd\u5c0d\u809d\u81df\u9020\u6210\u7684\u6b21\u7d1a\u6bd2\u6027\uff0c\u5728\u9ad4\u5916\u91cd\u73fe\u4e86\u8907\u96dc\u7684\u5168\u8eab\u6027\u85e5\u7269\u52d5\u529b\u5b78\u3002<\/p>\n

\u800c\u8fd1\u5e74\u4f86\uff0c\u88fd\u85e5\u516c\u53f8\u5df2\u958b\u59cb\u7a4d\u6975\u63a1\u7528\u6676\u7247\u5e73\u81fa\u9032\u884c\u65e9\u671f\u85e5\u7269\u7be9\u9078\uff0c\u4ee5\u4fbf\u5728\u6295\u5165\u6210\u672c\u9032\u5165\u52d5\u7269\u8a66\u9a57\u4e4b\u524d\uff0c\u5c31\u63d0\u65e9\u7be9\u9664\u7121\u6548\u6216\u6709\u6bd2\u5019\u9078\u85e5\u7269\u3002\u800c\u57282022\u5e74\uff0c\u7f8e\u570b\u570b\u6703\u901a\u904e\u4e86\u300aFDA\u73fe\u4ee3\u5316\u6cd5\u68482.0\u300b\uff0c\u8a72\u6cd5\u6848\u6b63\u5f0f\u6388\u6b0aFDA\u5728\u5be9\u6838\u65b0\u85e5\u6642\uff0c\u53ef\u4ee5\u63a5\u53d7\u57fa\u65bc\u5668\u5b98\u6676\u7247\u7b49\u66ff\u4ee3\u65b9\u6cd5\u7684\u6578\u64da\uff0c\u800c\u4e0d\u518d\u5f37\u5236\u8981\u6c42\u52d5\u7269\u8a66\u9a57\u3002\u96a8\u5f8c\u57282024\u5e749\u6708\uff0cEmulate\u516c\u53f8\u7684\u809d\u81df\u6676\u7247S1\uff0c\u6210\u70ba\u7b2c\u4e00\u500b\u88abFDA\u6b63\u5f0f\u63a5\u53d7\u4e26\u7d0d\u5165\u7684\u5668\u5b98\u6676\u7247\u6a21\u578b\u3002\u9019\u6a19\u8a8c\u8457\u5668\u5b98\u6676\u7247\u5df2\u4e0d\u518d\u662f\u5be6\u9a57\u5ba4\u4e2d\u7684\u6982\u5ff5\uff0c\u800c\u662f\u6b63\u5f0f\u8e0f\u4e0a\u4e86\u6210\u70ba\u81e8\u5e8a\u524d\u85e5\u7269\u8a55\u4f30\u6a19\u6e96\u5de5\u5177\u7684\u9053\u8def\u3002<\/p>\n

 <\/p>\n

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    \n
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  15. Polini, A., Prodanov, L., Bhise, N. S., Manoharan, V., Dokmeci, M. R., & Khademhosseini, A. (2014). Organs-on-a-chip: a new tool for drug discovery.\u00a0Expert opinion on drug discovery<\/em>,\u00a09<\/em>(4), 335-352.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

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