{"id":44277,"date":"2024-06-27T18:00:55","date_gmt":"2024-06-27T10:00:55","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=44277"},"modified":"2026-01-06T14:27:31","modified_gmt":"2026-01-06T06:27:31","slug":"%e5%a4%9a%e8%ae%8a%e5%a4%9a%e5%b7%b4%e8%83%ba-%e7%ac%ac%e4%b8%80%e9%83%a8%ef%bc%9achebi18243","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=44277","title":{"rendered":"\u591a\u8b8a\u591a\u5df4\u80fa\u2014\u2014\u7b2c\u4e00\u90e8\uff1aChEBI:18243"},"content":{"rendered":"

\u591a\u5df4\u80fa\u662f\u4ec0\u9ebc\uff1f\u5982\u679c\u4e00\u5f35\u5716\u5c31\u80fd\u544a\u8a34\u6211\u5011\u8a31\u591a\u591a\u5df4\u80fa\u77e5\u8b58\uff0c\u800c\u4e14\uff0c\u9019\u4e9b\u77e5\u8b58\u662f\u7531\u8a31\u591a\u79d1\u5b78\u5bb6\u5408\u529b\u5efa\u7acb\u5b8c\u6210\u7684\uff1b\u5982\u679c\u4e00\u5f35\u5716\u5c31\u80fd\u63d0\u4f9b\u591a\u5df4\u80fa\u95dc\u9375\u7684\u9023\u7d50\uff0c\u5c0d\u65bc\u6211\u5011\u5feb\u901f\u638c\u63e1\u591a\u5df4\u80fa\u7684\u8cc7\u8a0a\u7d50\u69cb\u6709\u591a\u5927\u5e6b\u52a9\uff1f\u8a66\u8a66\u770b\uff0c\u900f\u904e\u591a\u5df4\u80fa\u5728\u4e00\u500b\u77e5\u8b58\u5eab\u4e2d\u6709\u4e00\u500b\u8eab\u5206\u8b49\u865f\u78bc\uff1a18243\uff0cChEBI\u77e5\u8b58\u672c\u9ad4\uff0c\u958b\u59cb\u5e36\u9818\u6211\u5011\u900f\u8996\u5316\u5b78\u591a\u5df4\u80fa\u8207\u9023\u7d50\u5373\u6642\u66f4\u65b0\u7684\u8c50\u5bcc\u8cc7\u6e90\u63a2\u7d22\u65c5\u7a0b\u3002<\/strong><\/span><\/p>\n

\u64b0\u6587\uff5cA. H.<\/strong><\/p>\n

\u7e7c\u300a\u591a\u8b8a\u591a\u5df4\u80fa\u2014\u2014<\/strong>\u524d\u50b3<\/strong><\/a>\u300b\u5f97\u77e5\u591a\u5df4\u80fa\u7684\u77e5\u8b58\u5167\u5bb9\u6db5\u84cb\u591a\u8b8a\u9762\u5411\uff0c\u6703\u56e0\u6642\u7a7a\u8b8a\u5316\u800c\u8b8a\u5316\uff0c\u56e0\u89c0\u5bdf\u89d2\u5ea6\u4e0d\u540c\u800c\u4e0d\u540c\u3002\u901a\u5e38\u958b\u59cb\u4ecb\u7d39\u591a\u5df4\u80fa\u6642\uff0c\u6703\u8aaa\u660e\u300c\u5979\u300d\u662f\u5152\u8336\u915a\uff0f\u5152\u8336\u915a\u80fa\u548c\u82ef\u4e59\u80fa\u5bb6\u65cf\u7684\u6709\u6a5f\u5316\u5b78\u7269\u8cea\u3002\u4f46\u5148\u7b49\u7b49\uff0c\u7a81\u7136\u51fa\u73fe\u7684\u9019\u9ebc\u591a\u5316\u5408\u7269\u540d\u7a31\u662f\u4ec0\u9ebc\uff1f\u9019\u4e00\u8108\u7684\u79d1\u5b78\u5bb6\u65cf\u7956\u8b5c\u53c8\u662f\u600e\u56de\u4e8b\uff1f\u5c0d\u65bc\u8907\u96dc\u7684\u8cc7\u8a0a\uff0c\u6211\u5011\u53ef\u4ee5\u5229\u7528\u6574\u5408\u77e5\u8b58\u55ae\u4f4d\u5ee3\u5ea6\u548c\u6df1\u5ea6\u7684\u5229\u5668\uff0c\u4e5f\u5c31\u662f\u6240\u8b02\u7684\u77e5\u8b58\u5716\u8b5c (Knowledge Graph, KG) \u8207\u91d0\u6e05\u77e5\u8b58\u9593\u67b6\u69cb\u8207\u300c\u95dc\u4fc2\u300d\u7684\u77e5\u8b58\u672c\u9ad4 (ontology)\u3002\u9019\u88e1\u63d0\u5230\u7684\u672c\u9ad4\uff0c\u539f\u662f\u7531\u5404\u5b78\u9580\u5b78\u8005\u6240\u5efa\u7acb\uff0c\u63d0\u4f9b\u96fb\u8166\u300c\u7406\u89e3\u300d\u8cc7\u6599\u8a9e\u610f\u4f86\u904b\u7b97\uff0c\u4ee5\u6a5f\u5668\u53ef\u8b80\u7684\u901a\u7528\u683c\u5f0f\u9032\u884c\u63cf\u8ff0\uff0c\u6574\u5408\u5176\u4ed6\u77e5\u8b58\u4f86\u6e90\u61c9\u7528\u65bc\u4e0d\u540c\u9818\u57df\u7684\u65b9\u6cd5\u3002<\/p>\n

\"\"
\u57161\uff1a\u591a\u5df4\u80fa\u5728\u5316\u5b78\u77e5\u8b58\u67b6\u69cb\u4e2d\u5c6c\u65bc\u5152\u8336\u915a\uff0f\u5152\u8336\u915a\u80fa\u548c\u82ef\u4e59\u80fa\u5bb6\u65cf\uff5c\u4f86\u6e90\uff1a\u4f5c\u8005\u63d0\u4f9b<\/figcaption><\/figure>\n

\u5927\u5bb6\u6700\u719f\u6089\u7684KG\u83ab\u904e\u65bcGoogle\u641c\u5c0b\u7d50\u679c\u53f3\u5074\u986f\u793a\u7684\u8cc7\u8a0a\u6846\u4e86\u3002\u4f5c\u70ba\u4e00\u500b\u7406\u89e3\u73fe\u5be6\u4e16\u754c\u7684\u5be6\u9ad4 (entity) \u53ca\u5176\u5f7c\u6b64\u95dc\u4fc2 (relation) \u7684\u5716\u6846\uff0c\u76ee\u524d\u6700\u5e38\u51fa\u73fe\u7684\u5c31\u662f\u7d50\u69cb\u5316\u8cc7\u6599\u5eab\u2014\u2014\u7dad\u57fa\u767e\u79d1\u7684\u8cc7\u8a0a\uff0c\u800c\u9019\u80cc\u5f8c\u7684\u667a\u6167\u5176\u4e2d\u4e4b\u4e00\uff0c\u5c31\u662f\u4f86\u81ea\u672c\u9ad4\u7684\u8a9e\u610f\u67b6\u69cb\u30101\u3011,\u30102\u3011<\/sup>\u3002\u82e5\u5c07\u672c\u9ad4\u653e\u5728\u79d1\u666e\u8108\u7d61\u4e2d\uff0c\u5247\u6709\u52a9\u65bc\u6211\u5011\u5feb\u901f\u638c\u63a7\u8cc7\u8a0a\uff0c\u4e5f\u5c31\u662f\u6240\u8b02\u4e00\u5716\u52dd\u5343\u8a00\u3002\u56e0\u672c\u9ad4\u5177\u5099\u4e86\u5c07\u8cc7\u6599\u53ef\u8996\u5316\u3001\u7d50\u5408\u5716\u50cf\u8207\u6587\u5b57\u77e5\u8b58\u6a39\u7684\u512a\u52e2\uff0c\u5354\u52a9\u8b80\u8005\u5f9e\u719f\u6089\u7684\u8996\u89ba\u8868\u73fe\uff0c\u9032\u5165\u62bd\u8c61\u79d1\u5b78\u7406\u89e3\uff0c\u56e0\u6b64\u63a5\u4e0b\u4f86\u6211\u5011\u5c07\u5617\u8a66\u4f7f\u7528\u4e0d\u540c\u7684\u672c\u9ad4\uff0c\u4f86\u50b3\u9054\u591a\u5df4\u80fa\u8907\u96dc\u7684\u6545\u4e8b\uff0c\u5e36\u9818\u8b80\u8005\u5206\u5225\u5f9e\u5fae\u89c0\u548c\u5b8f\u89c0\u7684\u89d2\u5ea6\u7372\u5f97\u591a\u5df4\u80fa\u6982\u5ff5\uff0c\u4e26\u66f4\u6e96\u78ba\u5730\u7406\u89e3\u300c\u5979\u300d\u7684\u5c6c\u6027\u3001\u7d50\u69cb\u548c\u57fa\u672c\u77e5\u8b58\u3002<\/p>\n

 <\/p>\n

\u77e5\u8b58\u672c\u9ad4ChEBI<\/strong><\/span><\/h6>\n

\u4ee5\u751f\u7269\u91ab\u5b78\u672c\u9ad4\u800c\u8a00\uff0c\u6bcf\u500b\u77e5\u8b58\u55ae\u5143\uff08\u5be6\u9ad4\u6216\u7bc0\u9ede\uff09\u4ee3\u8868\u7684\u662f\u7279\u5b9a\u7684\u751f\u7269\u6216\u5316\u5b78\u5be6\u9ad4\uff08\u5982\u57fa\u56e0\u3001\u7d30\u80de\u3001\u75be\u75c5\u3001\u85e5\u7269\u7b49\uff09\uff0c\u63d0\u4f9b\u4e86\u6bcf\u500b\u5316\u5408\u7269\u91cd\u8981\u7684\u7279\u5fb5\u3002\u672c\u9ad4\u4e2d\uff0c\u6bcf\u500b\u9023\u7d50\u7684\u908a (relation) \u5247\u662f\u63cf\u8ff0\u5be6\u9ad4\u9593\u7684\u76f8\u4e92\u4f5c\u7528\u6216\u95dc\u4fc2\uff08\u5982\u300c\u85e5\u7269\u6cbb\u7642\u75be\u75c5\u300d\u6216\u300c\u7d30\u80de\u4e0a\u8abf\u57fa\u56e0\u300d\uff09\u3002\u56e0\u6b64\uff0c\u4ee5\u4f7f\u7528\u6a19\u6e96\u8a5e\u5f59\u7684\u300c\u751f\u7269\u611f\u8208\u8da3\u7684\u5316\u5b78\u5be6\u9ad4\u300d (Chemical Entities of Biological Interest, ChEBI<\/a>) \u4f5c\u70ba\u6b63\u5f0f\u77ad\u89e3\u591a\u5df4\u80fa\u7684\u5165\u9580\uff0c\u76f8\u7576\u7b26\u5408\u6211\u5011\u5c0d\u591a\u5df4\u80fa\u5206\u5b50\u7d50\u69cb\u3001\u5728\u751f\u7269\u5b78\u4e2d\u7684\u4f5c\u7528\u8207\u5be6\u9ad4\u9593\u901a\u7528\u548c\u5316\u5b78\u7279\u5b9a\u95dc\u4fc2\uff08\u5982\u57162\u63cf\u8ff0\u7684\u95dc\u4fc2\u985e\u578b\u8207\u5bb6\u65cf\u8b5c\u7cfb\uff09\uff0c\u540c\u6642\u517c\u9867\u4e86\u5ee3\u6cdb\u8207\u6df1\u5165\u7406\u89e3\u7684\u9700\u6c42\u3002<\/p>\n

\"\"
\u57162\uff1a\u591a\u5df4\u80fa\u5728ChEBI: 18243\u672c\u9ad4\u4e2d\u90e8\u5206\u77e5\u8b58\u67b6\u69cb\u6a39\u8996\u5716\uff5c\u4f86\u6e90\uff1a\u4f5c\u8005\u63d0\u4f9b<\/figcaption><\/figure>\n

ChEBI\u662f\u7e3d\u90e8\u8a2d\u5728\u6d77\u5fb7\u5821\u7684\u6b50\u6d32\u751f\u7269\u8cc7\u8a0a\u5b78\u7814\u7a76\u6240 (EMBL-EBI<\/a>) \u6240\u958b\u653e\u7684\u751f\u7269\u91ab\u5b78\u672c\u9ad4 (OBO<\/a>) \u7684\u4e00\u90e8\u5206\uff0c\u5c08\u6ce8\u65bc\u6574\u5408\u3001\u95e1\u8ff0\u300c\u5c0f\u300d\u5316\u5408\u7269\u7684\u8cc7\u6599\u3002\u300c\u5206\u5b50\u5be6\u9ad4\u300d\u662f\u6307\u4efb\u4f55\u7d50\u69cb\u4e0a\u6216\u540c\u4f4d\u7d20\u4e0a\u4e0d\u540c\u7684\u539f\u5b50\u3001\u5206\u5b50\u3001\u96e2\u5b50\u3001\u96e2\u5b50\u5c0d\u3001\u81ea\u7531\u57fa\u3001\u81ea\u7531\u57fa\u96e2\u5b50\u3001\u8907\u5408\u7269\u3001\u69cb\u8c61\u7570\u69cb\u7269\u7b49\u3002\u53ef\u8b58\u5225\u70ba\u55ae\u7368\u5340\u5206\u7684\u5be6\u9ad4\uff0c\u6240\u8a0e\u8ad6\u7684\u5206\u5b50\u5be6\u9ad4\u8981\u9ebc\u662f\u81ea\u7136\u7522\u7269\uff0c\u8981\u9ebc\u662f\u7528\u65bc\u5e72\u9810\u751f\u7269\u9ad4\u904e\u7a0b\u7684\u5408\u6210\u7522\u7269\u3002ChEBI\u5305\u542b\u672c\u9ad4\u5206\u985e\u8207\u6307\u5b9a\u5206\u5b50\u5be6\u9ad4\uff0c\u6216\u5be6\u9ad4\u985e\u5225\u8207\u5176\u7236\u6bcd\u548c\uff0f\u6216\u5b50\u5be6\u9ad4 (parents and\/or children) \u4e4b\u9593\u7684\u95dc\u4fc2\u30103\u3011<\/sup>\uff0c\u901a\u5e38\u63cf\u8ff0\u70ba\u300c\u7236\u5b50\u95dc\u4fc2\u300d\u3002<\/p>\n

 <\/p>\n

ChEBI\u672c\u9ad4\u4e2d\u7684\u591a\u5df4\u80fa<\/strong><\/span><\/h6>\n

\u591a\u5df4\u80fa (ChEBI\uff1a18243<\/a>) \u5728ChEBI\u4e2d\u7684\u5b9a\u7fa9\u70ba\uff1a\u5152\u8336\u915a\uff0c\u5176\u4e2d\uff0c4\u4f4d\u7684\u6c2b\u88ab2-aminoethyl\u7fa4\u53d6\u4ee3\u300218243\u662fChEBI\u63d0\u4f9b\u7d66\u6bcf\u500b\u5be6\u9ad4\u7684\u300c\u552f\u4e00\u8b58\u5225\u78bc\u300d\u3002\u5728\u57162\u4e2d\uff0cChEBI\uff1a18243\u662f\u4e3b\u65cf\u5206\u5b50\u5be6\u9ad4 (ChEBI\uff1a33579<\/a>) \u4e00\u65cf\uff0c\u5305\u542b\u5143\u7d20\u9031\u671f\u8868\u7b2c1\u30012\u300113\u300114\u300115\u300116\u300117\u548c18\u65cf\u4e2d\uff0c\u4efb\u4f55\u4e00\u7d44\u7684\u4e00\u500b\u6216\u591a\u500b\u539f\u5b50\u7684\u5206\u5b50\u5be6\u9ad4\u3002\u591a\u5df4\u80fa\u5728\u6b64\u6a39\u8996\u5716\u4e2d\uff0c\u53ef\u88ab\u63cf\u8ff0\u70ba\u300c\u662f\u4e00\u500b<\/em><\/strong>\u300d\u5152\u8336\u915a\u80fa (ChEBI\uff1a33567)\u3001\u55ae\u80fa\u5206\u5b50\u4fe1\u4f7f (ChEBI\uff1a25375) \u548c\u6709\u6a5f\u5206\u5b50\u5be6\u9ad4 (ChEBI\uff1a50860)\u3002<\/p>\n

\"\"
\u57163\uff1a\u591a\u5df4\u80fa (ChEBI: 18243) \u5728ChEBI\u672c\u9ad4\u7684\u5716\u5f62\u6aa2\u8996\u5448\u73fe\u300c\u662f\u300d\u548c\u300c\u5c6c\u65bc\u300d\u95dc\u4fc2\u7684\u53ef\u8996\u5316\uff5c\u4f86\u6e90\uff1a\u4f5c\u8005\u63d0\u4f9b<\/figcaption><\/figure>\n

\u7136\u800c\uff0c\u591a\u5df4\u80fa\u5728\u5316\u5b78\u5be6\u9ad4\u4e0a\uff0c\u9084\u5c6c\u65bc\u53e6\u4e00\u5206\u652f\u5bb6\u65cf\uff1a\u915a\u985e (ChEBI\uff1a33853)\u3002\u5982\u57163\u6240\u6aa2\u8996\u53ef\u77e5\uff0c\u591a\u5df4\u80fa\u4e5f\u300c\u662f\u4e00\u500b<\/em><\/strong>\u300d\u591a\u539f\u5b50\u5be6\u9ad4 (ChEBI\uff1a36357)\u3001\u6709\u6a5f\u82b3\u9999\u65cf\u5316\u5408\u7269 (ChEBI\uff1a33659)\uff0c\u662f\u5152\u8336\u915a (ChEBI\uff1a33566)\u3002\u800c\u5728\u57161\u4e2d\uff0c\u4ea6\u53ef\u5f97\u77e5\u591a\u5df4\u80fa\u7684\u5171\u8edb\u9e7c\u57fa\u548c\u5171\u8edb\u9178\u662f\u591a\u5df4\u80fa (1+) (ChEBI\uff1a59905)\uff0c\u662f\u4eba\u985e\u4ee3\u8b1d\u53cd\u61c9\u671f\u9593\u6240\u7522\u751f\u7684\u4efb\u4f55\u54fa\u4e73\u52d5\u7269\u300c\u4ee3\u8b1d\u7269\u300d\uff0c\u5728\u751f\u7269\u5b78\u4e0a\u7684\u4f5c\u7528\u8207\u795e\u7d93\u50b3\u5c0e\u7269\u8cea\u969c\u7919\u6709\u95dc\uff0c\u5f8c\u7e8c\u6587\u7ae0\u6211\u5011\u6703\u518d\u4f7f\u7528\u5176\u4ed6\u7684\u77e5\u8b58\u672c\u9ad4\u4f86\u9032\u4e00\u6b65\u4ecb\u7d39\u3002<\/p>\n

\"\"
\u57164\uff1a\u5728ChEBI\u672c\u9ad4\u4e2d\u67e5\u627e\u5305\u542b\u985e\u4f3c\u591a\u5df4\u80fa\u7d50\u69cb\u7684\u5316\u5408\u7269\uff5c\u4f86\u6e90\uff1aChEBI<\/figcaption><\/figure>\n

\u5728ChEBI\u7684\u4e00\u500b\u4e3b\u8981\u95dc\u4fc2\u985e\u5225\u300chas role\uff08\u5177\u6709\u4f5c\u7528\uff09\u300d<\/strong>\u4e2d\uff0c\u63cf\u8ff0\u4e86\u591a\u5df4\u80fa\u7684\u751f\u7269\u5b78\u4f5c\u7528 (ChEBI\uff1a24432<\/a>)\uff0c\u5305\u62ec\u4e86\u03b2-\u814e\u4e0a\u817a\u7d20\u80fd\u6fc0\u52d5\u5291\u3001\u5927\u8178\u687f\u83cc\u4ee3\u8b1d\u7269\u3001\u591a\u5df4\u80fa\u80fd\u85e5\u7269\u3001\u64ec\u4ea4\u611f\u795e\u7d93\u5291\u3001\u5c0f\u9f20\u4ee3\u8b1d\u7269\u4ee5\u53ca\u4eba\u9ad4\u4ee3\u8b1d\u7269\u3002\u800c\u61c9\u7528\u95dc\u4fc2<\/strong> (ChEBI\uff1a33232<\/a>) \u5247\u63cf\u8ff0\u4eba\u985e\u5c0d\u5206\u5b50\u5be6\u9ad4\u6216\u5176\u90e8\u5206\u7684\u9810\u671f\u7528\u9014\uff0c\u56e0\u6b64\u591a\u5df4\u80fa\u7684\u61c9\u7528\u5c64\u9762\u5305\u62ec\uff1a\u5f37\u5fc3\u85e5\u3001\u03b2-\u814e\u4e0a\u817a\u7d20\u80fd\u6fc0\u52d5\u5291\u3001\u591a\u5df4\u80fa\u80fd\u85e5\u7269\u8207\u64ec\u4ea4\u611f\u795e\u7d93\u5291\u7b49\uff0c\u4ea6\u5728\u672c\u9ad4\u4e2d\u6709\u63cf\u8ff0\u8207\u9023\u7d50\u3002\u82e5\u6211\u5011\u5229\u7528ChEBI\u4e2d\u7684\u300chas part (\u6709\u90e8\u5206)\u300d<\/strong>\u95dc\u4fc2\u67e5\u8a62\uff0c\u4e5f\u53ef\u627e\u5230\u5305\u542b\u591a\u5df4\u80fa\u7d50\u69cb\u7684\u5316\u5408\u7269\uff0c\u76ee\u524d\u81f3\u5c11\u5305\u62ec\u4e861372\u500b<\/a>\u5be6\u9ad4\uff0c\u4e5f\u53ef\u627e\u523059\u7a2e<\/a>\u985e\u4f3c\u65bc\u9019\u7a2e\u7d50\u69cb\u7684\u5316\u5408\u7269\uff0c\u5982\u57164\u6240\u793a\u3002<\/p>\n

\u6700\u65b0\u7248\u672c (2024\/04\/09) \u7684ChEBI\u6536\u9304\u4e86\u5305\u542b\u8fd16.2\u842c\u5316\u5408\u7269\u548c\u8d85\u904e19\u842c\u7b46\u7684\u300c\u95dc\u4fc2<\/a>\u300d\u3002ChEBI\u7684\u61c9\u7528\u5ee3\u6cdb\uff0c\u5305\u62ec\u751f\u7269\u91ab\u5b78\u77e5\u8b58\u5716\u8b5c\u7684\u5efa\u7f6e\u30104\u3011<\/sup>\u3001\u5176\u8c50\u5bcc\u5c64\u6b21\u7d50\u69cb\u548c\u5176\u4ed6\u95dc\u4fc2\u985e\u578b\uff0c\u53ef\u70ba\u8b58\u5225\u963f\u8332\u6d77\u9ed8\u6c0f\u75c7\u548c\u5931\u667a\u6587\u737b\u4e2d\u7684\u5316\u5b78\u5be6\u9ad4\u63d0\u4f9b\u6cbb\u7642\u7684\u5354\u52a9\u30105\u3011<\/sup>\u3002\u90a3\u9ebc\u6700\u5f8c\u518d\u554f\uff0c\u76f4\u63a5\u4f7f\u7528ChEBI\u7684\u591a\u5df4\u80fa\u8207\u5927\u773e\u76f4\u63a5\u6e9d\u901a\u884c\u5f97\u901a\u55ce\uff1f\u7576\u7136\u884c\uff01\u5982\u57165\u6240\u793a\uff0c\u7f8e\u570b\u570b\u5bb6\u91ab\u5b78\u5716\u66f8\u9928\u8207\u570b\u7acb\u885b\u751f\u7814\u7a76\u9662 (NIH) \u7684\u958b\u653e\u5316\u5b78\u8cc7\u6599\u5eabPubChem\uff0c\u4ee5ChEBI: 18243\u4f5c\u70ba\u63cf\u8ff0\u591a\u5df4\u80fa\u7684\u8cc7\u8a0a\u4f86\u6e90\u30106\u3011<\/sup>\u3002\u53e6\u5916\uff0c\u65b0\u805e\u5a92\u9ad4\u4ecb\u7d39\u591a\u5df4\u80fa\u5728\u75bc\u75db\u4e0a\u7684\u4f5c\u7528\u6642\u30107\u3011<\/sup>\uff0c\u5373\u662f\u76f4\u63a5\u5f15\u7528ChEBI: 18243\u4f5c\u70ba\u8cc7\u6599\u4f86\u6e90\u5594\uff01ChEBI\u6240\u63cf\u8ff0\u7684\u591a\u5df4\u80fa\u662f\u4e00\u500b\u5316\u5b78\u5be6\u9ad4\uff0c\u300c\u5979\u300d\u7684\u300c\u7d30\u80de\u5bb6\u65cf\u8b5c\u7cfb<\/strong>\u300d\u53c8\u662f\u4e00\u500b\u4ec0\u9ebc\u6a23\u7684\u6545\u4e8b\u5462\uff1f\uff08\u5f85\u7e8c\uff09<\/p>\n

\"\"
\u57165\uff1aPubChem\u4ee5ChEBI: 18243\u4f5c\u70ba\u63cf\u8ff0\u591a\u5df4\u80fa\u7684\u8cc7\u6599\u4f86\u6e90\uff5c\u4f86\u6e90\uff1aChEBI<\/figcaption><\/figure>\n

 <\/p>\n

\n

\u53c3\u8003\u6587\u737b<\/strong><\/p>\n

    \n
  1. Singhal, A. (2012), Introducing the Knowledge Graph: things, not strings.<\/a><\/li>\n
  2. Chah, N. (2018). OK Google, What Is Your Ontology? Or: Exploring Freebase Classification to Underst and Google's Knowledge Graph . arXiv preprint arXiv:1805.03885.<\/li>\n
  3. Degtyarenko, K., De Matos, P., Ennis, M., Hastings, J., Zbinden, M., McNaught, A., ... & Ashburner, M. (2007). ChEBI: a d atabase and ontology for chemical entities of biological interest. Nucleic acids research , 36(suppl_1), D344 D350.<\/li>\n
  4. Fern\u00e1ndez Torras, A., Duran Frigola, M., Bertoni, M., Locatelli, M., & Aloy, P. (2022). Integrating and formatting biomedical data as pre calculated knowledge graph embeddings in the Bioteque . Nature Communications, 13(1), 5304.<\/li>\n
  5. Mullin, S., McDougal, R., Cheung, K. H., Kilicog lu, H., Beck, A., & Zeiss, C. J. (2023). Chemical Entity Normalization for Successful Translational Development of Alzheimer's Disease and Dementia Therapeutics . Research Square, rs-3.<\/li>\n
  6. National Center for Biotechnology Information. PubChem Compound Summary for CID 681, Dopamine.\u00a0<\/a><\/li>\n
  7. News Medical. Role of Dopamine in Pain , Aug 21, 2023.<\/li>\n<\/ol>\n

     <\/p>\n

    \n

    \u2728\u5ef6\u4f38\u95b1\u8b80\uff1a\u300a\u591a\u8b8a\u591a\u5df4\u80fa\u2014\u2014\u524d\u50b3<\/a>\u300b<\/p>\n

    <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

    \u591a\u5df4\u80fa\u662f\u4ec0\u9ebc\uff1f\u5982\u679c\u4e00\u5f35\u5716\u5c31\u80fd\u544a\u8a34\u6211\u5011\u8a31\u591a\u591a\u5df4\u80fa\u77e5\u8b58\uff0c\u800c\u4e14\uff0c\u9019\u4e9b\u77e5\u8b58\u662f\u7531\u8a31\u591a\u79d1\u5b78\u5bb6\u5408\u529b\u5efa\u7acb\u5b8c\u6210\u7684\uff1b\u5982\u679c\u4e00\u5f35\u5716\u5c31\u80fd\u63d0\u4f9b\u591a\u5df4\u80fa\u95dc\u9375\u7684\u9023\u7d50\uff0c\u5c0d\u65bc\u6211\u5011\u5feb\u901f\u638c\u63e1\u591a\u5df4\u80fa\u7684\u8cc7\u8a0a\u7d50\u69cb\u6709\u591a\u5927\u5e6b\u52a9\uff1f\u8a66\u8a66\u770b\uff0c\u900f\u904e\u591a\u5df4\u80fa\u5728\u4e00\u500b\u77e5\u8b58\u5eab\u4e2d\u6709\u4e00\u500b\u8eab\u5206\u8b49\u865f\u78bc\uff1a18243\uff0cChEBI\u77e5\u8b58\u672c\u9ad4\uff0c\u958b\u59cb\u5e36\u9818\u6211\u5011\u900f\u8996\u5316\u5b78\u591a\u5df4\u80fa\u8207\u9023\u7d50\u5373\u6642\u66f4\u65b0\u7684\u8c50\u5bcc\u8cc7\u6e90\u63a2\u7d22\u65c5\u7a0b\u3002<\/p>\n","protected":false},"author":20,"featured_media":44280,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32,7498,3293,6512],"tags":[7136,7135,928,2412,5562],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/06\/DA-ChEBI_1.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/44277"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=44277"}],"version-history":[{"count":1,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/44277\/revisions"}],"predecessor-version":[{"id":44283,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/44277\/revisions\/44283"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/44280"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=44277"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=44277"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=44277"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}