{"id":44043,"date":"2024-04-24T18:00:42","date_gmt":"2024-04-24T10:00:42","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=44043"},"modified":"2026-01-06T14:27:49","modified_gmt":"2026-01-06T06:27:49","slug":"44043","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=44043","title":{"rendered":"\u591a\u8b8a\u591a\u5df4\u80fa\u2014\u2014\u524d\u50b3"},"content":{"rendered":"<p><span style=\"color: #000080;\"><strong>\u591a\u5df4\u80fa\u61c9\u8a72\u662f\u6700\u70ba\u5927\u773e\u6240\u719f\u77e5\u7684\u4eba\u9ad4\u5167\u795e\u7d93\u50b3\u905e\u7269\u8cea\uff0c\u7562\u7adf\u300c\u5feb\u6a02\u5206\u5b50\u300d\u8ab0\u4e0d\u559c\u6b61\u5462\uff1f\u4f46\u4f60\u77e5\u9053\u55ce\uff1f\u591a\u5df4\u80fa\u53ef\u6c92\u6709\u9019\u9ebc\u7c21\u55ae\u5594\uff01\u5979\u5728\u4eba\u9ad4\u5167\u6240\u626e\u6f14\u7684\u89d2\u8272\u81f3\u4eca\u4f9d\u7136\u773e\u8aaa\u7d1b\u7d1c\uff0c\u751a\u81f3\u7d93\u5e38\u50b3\u51fa\u5979\u5728\u54ea\u500b\u884c\u70ba\u3001\u53cd\u61c9\u7576\u4e2d\uff0c\u53c8\u51fa\u4e4e\u610f\u6599\u5730\u5982\u4f55\u5f71\u97ff\u8457\u6211\u5011\u3002\u672c<\/strong><strong>\u6587\u85c9\u64ec\u4eba\u5316\u79d1\u5b78\u8cc7\u8a0a\u4e3b\u984c\uff0c\u5c07\u591a\u5df4\u80fa\u5728\u79d1\u5b78\u53f2\u4e0a\u767c\u5c55\u7684\u904e\u7a0b\u3001\u4e0d\u540c\u968e\u6bb5\u6240\u767c\u73fe\u7684\u4e0d\u540c\u7279\u6027\uff0c\u4ee5\u5c11\u5973\u6210\u9577\u904e\u7a0b\u4f5c\u70ba\u6bd4\u55bb\u4f86\u89c0\u5bdf\u548c\u7406\u89e3\uff0c\u4f86\u4f5c\u70ba\u8a8d\u8b58\u8ff7\u4eba\u591a\u5df4\u80fa\u5b8c\u6574\u77e5\u8b58\u67b6\u69cb\u7684\u524d\u5c0e\u6545\u4e8b\u3002<\/strong><\/span><\/p>\n<p><strong>\u64b0\u6587\uff5cA.H.<\/strong><\/p>\n<p>\u5927\u8166\u4e2d\u7684\u300c\u591a\u5df4\u80fa\u300d (dopamine) \u5728\u65e5\u5e38\u7684\u8a31\u591a\u4e0d\u540c\u9762\u76f8\u4e2d\u5747\u5f71\u97ff\u8457\u6211\u5011\uff0c\u5305\u62ec\u8abf\u7bc0\u60c5\u7dd2\u3001\u5b78\u7fd2\u3001\u8a18\u61b6\u548c\u904b\u52d5\u7b49\u3002\u81f3\u65bc\u5728\u9ad4\u5167\u7684\u591a\u5df4\u80fa\uff0c\u4e5f\u626e\u6f14\u8457\u91cd\u8981\u7684\u89d2\u8272\uff0c\u4e0d\u50c5\u548c\u8840\u7ba1\u6536\u7e2e\uff0f\u653e\u9b06\u7684\u7a0b\u5ea6\u6709\u95dc\uff0c\u7576\u8840\u7cd6\u904e\u4f4e\u6642\u4e5f\u6703\u6e1b\u5c11\u80f0\u5cf6\u7d20\u7684\u7522\u751f\uff0c\u540c\u6642\u9084\u80fd\u4fdd\u8b77\u8178\u9053\u5167\u58c1\u3002\u96d6\u7136\u300c\u5979\u300d\u80fd\u5920\u5e36\u7d66\u6211\u5011\u8af8\u591a\u826f\u597d\u7684\u6548\u76ca\uff0c\u4f46\u7576\u300c\u5979\u300d\u5931\u8861\u6642\uff0c\u4e5f\u6703\u5e36\u4f86\u56b4\u91cd\u7684\u5f8c\u679c\u3002\u7576\u591a\u5df4\u80fa\u4e0d\u8db3\u6642\uff0c\u53ef\u80fd\u6703\u5f15\u767c\u5e15\u91d1\u68ee\u6c0f\u75c7\uff1b\u7576\u592a\u591a\u6642\uff0c\u5247\u6703\u5c0e\u81f4\u4f4e\u8840\u58d3\u3001\u5e7b\u89ba\u3001\u885d\u52d5\u63a7\u5236\u969c\u7919\uff0c\u9020\u6210\u5982\u6210\u766e\u3001\u8e81\u72c2\u75c7\u548c\u589e\u52a0\u653b\u64ca\u6027\u7b49\u554f\u984c\u3002\u300c\u5979\u300d\u5c31\u50cf\u4e00\u4f4d\u5584\u5992\u7684\u60c5\u4eba\uff0c\u6709\u6642\u53ef\u4ee5\u662f\u4e00\u822c\u4eba\u53e3\u4e2d\u7684\u300c\u5feb\u6a02\u591a\u5df4\u80fa\u300d\uff0c\u6709\u6642\u4e5f\u80fd\u8b93\u4eba\u300c\u6a02\u6975\u60b2\u751f\u300d\u3002\u5728\u6df1\u5165\u77ad\u89e3\u591a\u5df4\u80fa\u4e4b\u524d\uff0c\u6211\u5011\u5148\u4f86\u4e00\u7aba\u300c\u5979\u300d\u5728\u79d1\u5b78\u4e0a\u7684\u5f62\u5851\u6b77\u7a0b\u3002\u6216\u8a31\u4f60\u5df2\u7d93\u767c\u73fe\u4e86\uff0c\u672c\u6587\u4e00\u76f4\u4ee5\u5973\u6027\u7684\u7b2c\u4e00\u4eba\u7a31\u4f86\u7a31\u547c\u591a\u5df4\u80fa\uff0c\u9019\u662f\u70ba\u4e86\u5411\u7b2c\u4e00\u4f4d\u767c\u73fe\u7684\u5973\u6027\u79d1\u5b78\u5bb6\u81f4\u656c\u3002<\/p>\n<p>&nbsp;<\/p>\n<h6><span style=\"color: #ffcc00;\"><strong>\u5c11\u5973\u591a\u5df4\u80fa\uff1a\u5f9e\u75be\u75c5\u7814\u7a76\u958b\u59cb\u805e\u540d<\/strong><\/span><\/h6>\n<p>1957\u5e74\uff0c\u591a\u5df4\u80fa\u5728\u502b\u6566\u90ca\u5916\u300c\u8a95\u751f\u300d\uff08\u5728\u4eba\u8166\u4e2d\u767c\u73fe\u7684\u6642\u9593\uff09\u4e86\u3002\u9996\u4f4d\u767c\u73fe\u8005\u2014\u2014\u51f1\u745f\u7433\u00b7\u8499\u5854\u53e4 (Kathleen Montagu) \u900f\u904e\u6ffe\u7d19\u8272\u5c64\u5206\u6790\u6cd5\uff0c\u5728\u8a31\u591a\u7269\u7a2e\u7684\u5927\u8166\u4e2d\u9451\u5b9a\u51fa\u4e86\u5b58\u5728\u591a\u5df4\u80fa\u7684\u8b49\u64da\uff0c\u5176\u4e2d\u4e5f\u5305\u62ec\u4e86\u4eba\u985e\u3002\u96a8\u5f8c\uff0c1958\u5e74\u745e\u5178\u570b\u5bb6\u5fc3\u81df\u7814\u7a76\u6240\u7684\u963f\u723e\u7dad\u5fb7\uff0e\u5361\u723e\u68ee (Arvid Carlsson) \u548c\u540c\u4e8b\u767c\u73fe\u4e86\u591a\u5df4\u80fa\u5177\u6709\u795e\u7d93\u905e\u8cea\u7684\u529f\u80fd\u3002\u57282000\u5e74\uff0c\u6301\u7e8c\u6295\u5165\u65bc\u591a\u5df4\u80fa\u7814\u7a76\u7684\u5361\u723e\u68ee\u7372\u9812\u8afe\u8c9d\u723e\u751f\u7406\u5b78\u91ab\u5b78\u734e\uff0c\u56e0\u70ba\u4ed6\u767c\u73fe\u591a\u5df4\u80fa\u4e0d\u50c5\u662f\u53bb\u7532\u814e\u4e0a\u817a\u7d20\u548c\u814e\u4e0a\u817a\u7d20\u7684\u300c\u524d\u9a45\u7269\u8cea (precursor)\u300d\u2014\u2014\u6307\u5728\u4ee3\u8b1d\u9014\u5f91\u4e2d\uff0c\u751f\u6210\u53e6\u4e00\u7a2e\u7269\u8cea\u524d\u7684\u539f\u59cb\u5316\u5408\u7269\u2014\u2014\u800c\u4e14\u672c\u8eab\u4ea6\u662f\u4e00\u7a2e\u300c\u795e\u7d93\u50b3\u5c0e\u7269\u8cea\u300d (neurotransmitter)\uff08\u5716\u4e00\uff09\u3002<\/p>\n<figure id=\"attachment_44044\" aria-describedby=\"caption-attachment-44044\" style=\"width: 800px\" class=\"wp-caption aligncenter\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-large wp-image-44044\" src=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA1_AH_20240318-1024x576.png\" alt=\"\" width=\"800\" height=\"450\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA1_AH_20240318-1024x576.png 1024w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA1_AH_20240318-300x169.png 300w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA1_AH_20240318-768x432.png 768w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA1_AH_20240318.png 1280w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption id=\"caption-attachment-44044\" class=\"wp-caption-text\">\u5716\u4e00\uff1a1957 \u5e74\u502b\u6566 \u827e\u585e\u514b\u65af\u90e1 (Essex) \u7684Runwell\u91ab\u9662\u5be6\u9a57\u5ba4\u767c\u73fe\u591a\u7269\u7a2e\u7684\u5927\u8166\u4e2d\u5b58\u5728\u591a\u5df4\u80fa\uff088\u67083\u65e5\u662f\u8ad6\u6587\u767c\u8868\u6642\u9593\uff09\u3002\u591a\u5df4\u80fa1910\u5e74\u7531\u82f1\u570b\u502b\u6566\u60e0\u5eb7\u5be6\u9a57\u5ba4\u55ac\u6cbb\uff0e\u5df4\u5091 (George Barger) \u548c\u8a79\u59c6\u65af\uff0e\u57c3\u6587\u65af (James Ewens) \u9996\u6b21\u5408\u6210\u3002\u5b83\u88ab\u547d\u540d\u70ba\u300c\u591a\u5df4\u80fa\u300d\uff0c\u56e0\u70ba\u5b83\u662f\u4e00\u7a2e\u55ae\u80fa\uff0c\u5408\u6210\u904e\u7a0b\u4e2d\u7684\u524d\u9ad4\u662f\u5de6\u65cb\u591a\u5df4 (L-DOPA)\u3002 1958\u5e74\u745e\u5178\u570b\u5bb6\u5fc3\u81df\u7814\u7a76\u6240\u963f\u723e\u7dad\u5fb7\uff0e\u5361\u723e\u68ee (Arvid Carlsson) \u548c\u540c\u4e8b\u767c\u73fe\u4e86\u591a\u5df4\u80fa\u795e\u7d93\u905e\u8cea\u7684\u529f\u80fd\uff5c\u4f86\u6e90\uff1a\u4f5c\u8005\u63d0\u4f9b<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<p>\u5341\u6b72\u524d\u7684\u591a\u5df4\u80fa\u5728\u79d1\u5b78\u754c\u9ed8\u9ed8\u7121\u540d\uff0c\u4e00\u76f4\u5230\u4e861967\u5e74\uff0c\u56e0\u5de6\u65cb\u591a\u5df4 (L-DOPA) \u7684\u7814\u7a76\u53d6\u5f97\u7a81\u7834\uff0c\u5728\u5f8c\u7e8c\u7684\u5341\u5e74\u9593\uff0c\u52a0\u901f\u4e86\u5927\u8166\u4e2d\u7684\u529f\u80fd\u3001\u53d7\u9ad4\u9452\u5b9a\u53ca\u76f8\u95dc\u85e5\u7406\u5b78\u3001\u6297\u7cbe\u795e\u75c5\u85e5\u7269\u7b49\u65b9\u9762\u7684\u7814\u7a76\u71b1\u6f6e\u3002\u7576\u591a\u5df4\u80fa\u4e8c\u5341\u5e7e\u6b72\u6642\uff0c\u5728\u5b78\u8853\u63a2\u7d22\u4e2d\u7684\u77e5\u540d\u5ea6\u6f38\u6f38\u6253\u958b\u4e86\uff0c\u4eba\u5011\u5c0d\u65bc\u5979\u7684\u7406\u89e3\u4e5f\u9010\u6f38\u6210\u5f62\u3002<\/p>\n<p>\u82e5\u62c6\u89e3\u591a\u5df4\u80fa\u7684\u540d\u7a31\uff0c\u300c\u80fa\u300d\u662f\u5979\u7684\u300c\u59d3\u6c0f\u300d\uff0c\u8868\u793a\u5176\u5c6c\u65bc\u5152\u8336\u915a\u80fa\u548c\u82ef\u4e59\u80fa\u9019\u4e8c\u5927\u80fa\u6c0f\u5bb6\u65cf\u7684\u6709\u6a5f\u5316\u5b78\u7269\u8cea\uff1b\u300c\u591a\u5df4\u300d\u5247\u662f\u5979\u7684\u300c\u540d\u300d\uff0c\u8868\u793a\u70ba\u5de6\u65cb\u591a\u5df4\u7684\u524d\u9a45\u5316\u5b78\u7269\u8cea\u3002\u6709\u8da3\u7684\u662f\uff0c\u300c\u591a\u5df4\u300d\u9019\u500b\u8a5e\u9084\u662f\u6587\u85dd\u5fa9\u8208\u6642\u671f\u5728\u9b54\u6cd5\u8853\u8a9e\u4e2d\uff0c\u4ee3\u8868\u300c\u963f\u591a\u5df4\u795e (ADOPA)\u300d\u6240\u5275\u9020\u7684\u4e00\u500b\u81ea\u7136\u754c\u7269\u8cea\u300c\u591a\u5df4\u5c0f\u5929\u4f7f\u300d\u5462\uff08\u5716\u4e8c\uff09\uff01<\/p>\n<figure id=\"attachment_44046\" aria-describedby=\"caption-attachment-44046\" style=\"width: 998px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-44046 size-full\" src=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA2_AH_20240318.png\" alt=\"\" width=\"998\" height=\"667\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA2_AH_20240318.png 998w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA2_AH_20240318-300x201.png 300w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA2_AH_20240318-768x513.png 768w\" sizes=\"(max-width: 998px) 100vw, 998px\" \/><figcaption id=\"caption-attachment-44046\" class=\"wp-caption-text\">\u5716\u4e8c\uff1a\u7db2\u969b\u7db2\u8def\u6a94\u6848\u9928 (Internet Archive) \u516c\u5171\u5716\u66f8\u9928\u6b77\u53f2\u8cc7\u6599\u5178\u85cf\u9801\u9762\uff1a\u5341\u516d\u4e16\u7d00\u82f1\u570b\u6578\u5b78\u5bb6\u3001\u5929\u6587\u5b78\u5bb6\u3001\u795e\u7955\u5b78\u5bb6\u7d04\u7ff0\uff0e\u8fea\u4f0a (John Dee) \u7684\u4ee5\u8afe\u9b54\u6cd5 (Enochian Magic) \u66f8\u4e2d\uff0c\u591a\u5df4\u662f\u81ea\u7136\u754c\u7269 \u8cea\u7684\u4e00\u500b\u5c0f\u5929\u4f7f\uff5c\u4f86\u6e90\uff1a\u4f5c\u8005\u63d0\u4f9b<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<h6><span style=\"color: #ffcc00;\"><strong>\u9752\u5e74\u6642\u671f\u591a\u5df4\u80fa\uff1a\u5feb\u6a02\u4ee3\u8a00\u4eba<\/strong><\/span><\/h6>\n<p>\u4e8c\u5341\u4e00\u6b72\u7684\u591a\u5df4\u80fa\uff0c\u4fbf\u5960\u5b9a\u4e86\u5979\u5f8c\u4f86\u6700\u88ab\u5ee3\u70ba\u6d41\u50b3\u7684\u8eab\u5206:\u300c\u5feb\u6a02\u6fc0\u7d20\u300d\u3001\u300c\u5feb\u6a02\u8cc0\u723e\u8499\u300d\u3001\u300c\u5feb\u6a02\u5206\u5b50\u300d\u30021978\u5e74\uff0c\u7f85\u4f0a\u00b7\u61f7\u65af (Roy Wise) \u767c\u8868\u4e86\u4e00\u7bc7\u958b\u5275\u6027\u8ad6\u6587\uff1a\u767c\u73fe\u591a\u5df4\u80fa\u81f3\u5c11\u5728\u5927\u8166\u4e2d\u90e8\u9644\u8fd1\u7684\u8ff4\u8def\u7522\u751f\u300c\u826f\u597d\u611f\u89ba\u300d\u7684\u4f5c\u7528\u6642\uff0c\u662f\u4e00\u9805\u5fc5\u8981\u7684\u689d\u4ef6\u3002\u63a5\u4e0b\u4f86\u61f7\u65af\u63d0\u51fa\u7684\u5047\u8aaa\uff1a\u591a\u5df4\u80fa\u662f\u4e00\u7a2e\u300c\u5feb\u6a02\u300d\u8a0a\u865f\uff0c\u6210\u70ba\u4e86\u591a\u5df4\u80fa\u8207\u5feb\u6a02\u9023\u7d50\u7684\u57fa\u790e\u3002<\/p>\n<p>&nbsp;<\/p>\n<h6><span style=\"color: #ffcc00;\"><strong>\u591a\u5df4\u80fa\u56db\u5341\u800c\u4e0d\u60d1\uff1f\u5728\u4e4e\u734e\u52f5\u52d5\u6a5f\u8207\u76ee\u6a19<\/strong><\/span><\/h6>\n<p>\u591a\u5df4\u80fa\u8207\u5feb\u6a02\u639b\u52fe\u7684\u8eab\u5206\u7dad\u6301\u4e86\u7d0420\u5e74\uff0c\u7136\u800c\uff0c\u7576\u5979\u5230\u4e86\u56db\u5341\u4e00\u6b72\u7684\u719f\u5973\u968e\u6bb5\u6642\uff0c\u4f3c\u4e4e\u5df2\u7d93\u7121\u6cd5\u4fdd\u6301\u4f4f\u5feb\u6a02\u5206\u5b50\u7684\u540d\u5206\u4e86\u3002\u80af\u7279\uff0e\u8c9d\u91cc\u5947 (Kent Berridge) \u548c\u7279\u91cc\uff0e\u7f85\u8cd3\u905c (Terry Robinson) \u57281998\u5e74\u63d0\u51fa\u7406\u8ad6\uff0c\u8a8d\u70ba\u591a\u5df4\u80fa\u4e26\u975e\u662f\u50b3\u9054\u5feb\u6a02\u611f\u89ba\u7684\u795e\u7d93\u905e\u8cea\uff0c\u800c\u662f\u8abf\u7bc0\u734e\u52f5\u7cfb\u7d71\u4e26\u89f8\u767c\u300c\u60f3\u8981\u300d\u617e\u671b\u7684\u523a\u6fc0\u56e0\u7d20\u3002\u9019\u9805\u7814\u7a76\u4e0d\u50c5\u767c\u5c55\u51fa\u4e86\u7576\u4ee3\u6210\u766e\u7406\u8ad6\uff0c\u4e26\u91cd\u65b0\u5c07\u591a\u5df4\u80fa\u5b9a\u7fa9\u70ba\u300c\u617e\u671b\u4fe1\u865f\u300d\uff1a\u591a\u5df4\u80fa\u7cfb\u7d71\u53ef\u4ee5\u8abf\u7bc0\u734e\u52f5\u7684\u6fc0\u52f5\u986f\u8457\u6027\uff0c\u4ee5\u4e00\u7a2e\u8207\u4eab\u6a02\u548c\u734e\u52f5\u5b78\u7fd2\u5206\u958b\u7684\u65b9\u5f0f\u8abf\u7bc0\u6fc0\u52f5\u50f9\u503c\u3002<\/p>\n<p>\u4ed6\u5011\u5728\u8ad6\u6587\u4e2d\u660e\u78ba\u5730\u8aaa\uff1a\u300c\u591a\u5df4\u80fa\u7cfb\u7d71\u5c0d\u65bc\u300c\u60f3\u8981\u300d\u7684\u6fc0\u52f5\u662f\u5fc5\u8981\u7684\uff0c\u4f46\u5c0d\u65bc\u300c\u559c\u6b61\u300d\u6216\u5b78\u7fd2\u65b0\u7684\u300c\u559c\u6b61\u300d\u548c\u300c\u4e0d\u559c\u6b61\u300d\u537b\u4e0d\u662f\u5fc5\u9700\u7684\u3002\u300d<\/p>\n<p>\u9032\u5165\u4e8c\u5341\u4e00\u4e16\u7d00\u5f8c\uff0c\u591a\u5df4\u80fa\u7684\u591a\u8b8a\u6027\u4f7f\u5f97\u5979\u7684\u78ba\u5207\u6027\u8cea\u6301\u7e8c\u53d7\u5230\u6311\u6230\u3002\u7d04\u7ff0\u00b7\u85a9\u62c9\u8499 (John Salamone) \u548c\u6885\u723e\u585e\u00b7\u79d1\u96f7\u4e9e (Merc\u00e8 Correa) \u57282012\u5e74\u4ee5\u300c\u795e\u7955\u52d5\u6a5f\u529f\u80fd\u300d\u7684\u8ad6\u6587\uff0c\u5c07\u9019\u6bb5\u6642\u671f\u4e0d\u65b7\u8b8a\u5316\u7684\u76f8\u95dc\u7406\u8ad6\u9032\u884c\u6574\u7406\u8207\u8a0e\u8ad6\uff0c\u4e26\u6307\u51fa\u591a\u5df4\u80fa\u66fe\u7d93\u88ab\u8a8d\u70ba\u5177\u6709\u7684\u6a19\u8a8c\u300c\u4eab\u6a02\u300d\u6216\u300c\u734e\u52f5\u300d\u529f\u80fd\uff0c\u5176\u5be6\u6240\u53cd\u6620\u7684\u662f\u66f4\u8907\u96dc\u7684\u300c\u52d5\u6a5f\u548c\u76ee\u6a19\u5c0e\u5411\u884c\u52d5\u300d\u8abf\u7bc0\u529f\u80fd\uff0c\u4f8b\u5982\uff1a\u52aa\u529b\u904e\u7a0b\u3001\u5c0d\u52aa\u529b\u76f8\u95dc\u6216\u6a5f\u6703\u6210\u672c\u7684\u611f\u77e5\u4ee5\u53ca\u6c7a\u7b56\u7b49\u3002\u800c\u5176\u4ed6\u65b0\u7814\u7a76\u4e5f\u767c\u73fe\uff0c\u591a\u5df4\u80fa\u795e\u7d93\u5143\u8207\u53ad\u60e1\u523a\u6fc0\u7684\u53cd\u61c9\uff0c\u4ee5\u53ca\u5f37\u5316\u5b78\u7fd2\u6216\u7fd2\u6163\u5f62\u6210\u7b49\u884c\u70ba\u7686\u6709\u6240\u95dc\u806f\u3002\u96a8\u8457\u6982\u5ff5\u4e0d\u65b7\u767c\u5c55\uff0c\u591a\u5df4\u80fa\u5728\u8166\u90e8\u6fc0\u6d3b\u3001\u53c3\u8207\u53cd\u61c9\u904e\u7a0b\u6240\u9020\u6210\u7684\u5f71\u97ff\uff0c\u5c0d\u65bc\u6291\u9b31\u3001\u7cbe\u795e\u5206\u88c2\u3001\u85e5\u7269\u6feb\u7528\u548c\u5176\u4ed6\u75be\u75c5\u60a3\u8005\u7684\u52d5\u6a5f\u529f\u80fd\u969c\u7919\u7b49\u7684\u75c5\u7406\u5206\u6790\uff0c\u5177\u6709\u4e86\u66f4\u986f\u8457\u7684\u81e8\u5e8a\u610f\u7fa9\u3002<\/p>\n<p>\u591a\u5df4\u80fa\u7684\u78ba\u5207\u6027\u8cea\u4e00\u76f4\u662f\u5099\u53d7\u722d\u8b70\u7684\u554f\u984c\u3002\u7f8e\u570b\u300a\u79d1\u5b78\u4eba\u300b\u57282017\u5e74\u7684\u4e00\u7bc7\u6587\u7ae0\uff0c\u5167\u5bb9\u662f\u5728\u63a2\u8a0e\u591a\u5df4\u80fa\u9019\u7a2e\u300c\u617e\u671b\u8ca8\u5e63\u300d\u5728\u79d1\u5b78\u4e0a\u5c0d\u65bc\u751f\u7406\u4f5c\u7528\u7684\u4e0d\u78ba\u5b9a\u6027\u3002\u6587\u4e2d\u6307\u51fa\uff0c\u4e00\u4e9b\u7814\u7a76\u8a8d\u70ba\uff0c\u5728\u5927\u8166\u7684\u734e\u52f5\u7cfb\u7d71\u4e2d\uff0c\u662f\u7531\u591a\u5df4\u80fa\u767c\u51fa\u617e\u671b\u4fe1\u865f\uff0c\u4f7f\u5f97\u6211\u5011\u6703\u60f3\u53bb\u9032\u884c\u7279\u5b9a\u7684\u884c\u70ba\uff1b\u53e6\u4e00\u6d3e\u5247\u5f37\u8abf\uff0c\u6211\u5011\u6703\u505a\u51fa\u7279\u5b9a\u7684\u884c\u70ba\uff0c\u662f\u56e0\u70ba\u5927\u8166\u6703\u5148\u9810\u6e2c\u505a\u51fa\u884c\u70ba\u5f8c\u6240\u7372\u5f97\u7684\u734e\u52f5\uff0c\u4e26\u6307\u5c0e\u6211\u5011\u505a\u51fa\u76f8\u61c9\u7684\u884c\u70ba\u3002\u6b64\u5916\uff0c\u53e6\u5916\u9084\u6709\u8ad6\u9ede\u5247\u662f\u5c07\u5169\u6d3e\u7684\u89c0\u9ede\u5dee\u7570\u5206\u958b\u4f86\u770b\uff0c\u4f46\u5169\u7a2e\u89e3\u91cb\u5747\u6709\u6548\u3002\u7e3d\u4e4b\uff0c\u79d1\u5b78\u7684\u5171\u8b58\u5c31\u662f\u591a\u5df4\u80fa\u5728\u795e\u7d93\u5b78\u4e0a\u96d6\u4e0d\u80fd\u5b9a\u7fa9\u5feb\u6a02\uff0c\u4f46\u537b\u80fd\u5e6b\u52a9\u6211\u5011\u89e3\u958b\u5927\u8166\u795e\u7d93\u905e\u8cea\u932f\u7d9c\u8907\u96dc\u7684\u5967\u7955\u3002<\/p>\n<p>&nbsp;<\/p>\n<h6><span style=\"color: #ffcc00;\"><strong>\u4eca\u65e5\u591a\u5df4\u80fa\uff1a\u98a8\u60c5\u842c\u7a2e\uff0c\u591a\u8b8a\u5f97\u4ee4\u79d1\u5b78\u8457\u8ff7<\/strong><\/span><\/h6>\n<p>\u4eca\u5e74\u5df2\u7d9367\u6b72\u7684\u591a\u5df4\u80fa\uff0c\u5728\u79d1\u5b78\u4e0a\u6211\u5011\u5df2\u77e5\u5979\u4e3b\u8981\u5c45\u4f4f\u5728\u4e2d\u8166\u7684\u8179\u5074\u84cb\u5340\u3001\u9ed1\u8cea\u7dfb\u5bc6\u90e8\u3001\u4e0b\u4e18\u8166\u5f13\u72c0\u6838\u7684\u591a\u5df4\u80fa\u795e\u7d93\u5143\uff0c\u4ee5\u53ca\u80c3\u8178\u9053\u4e2d\u3002\u5979\u4e0d\u50c5\u80fd\u548c\u03b3-\u6c28\u57fa\u4e01\u9178 (GABA) \u5354\u540c\u5408\u4f5c\uff0c\u5e6b\u52a9\u55c5\u89ba\u611f\u89ba\u795e\u7d93\u5143\u6aa2\u6e2c\u548c\u5340\u5206\u4e0d\u540c\u7684\u6c23\u5473\uff0c\u82e5\u548c\u8840\u6e05\u7d20\u52d5\u614b\u76f8\u4e92\u4f5c\u7528\uff0c\u4e5f\u80fd\u5920\u5f71\u97ff\u4eba\u985e\u793e\u6703\u7684\u884c\u70ba\u3002<\/p>\n<p>\u5982\u4eca\u7684\u591a\u5df4\u80fa\u5df2\u4e0d\u662f\u55ae\u7d14\u7684\u8166\u5167\u5316\u5b78\u7269\u8cea\u800c\u5df2\uff0c\u6211\u5011\u5c0d\u300c\u5979\u300d\u7684\u8a8d\u8b58\uff0c\u9664\u4e86\u65e9\u671f\u7684\u5feb\u6a02\u5206\u5b50\u3001\u4e2d\u671f\u7684\u617e\u671b\u4fe1\u865f\u3001\u734e\u52f5\u7cfb\u7d71\u3001\u52d5\u6a5f\u529f\u80fd\uff0c\u4ee5\u53ca\u5f8c\u4f86\u66f4\u8907\u96dc\u7684\u52d5\u6a5f\u548c\u76ee\u6a19\u5c0e\u5411\u884c\u52d5\u8abf\u7bc0\u9ad8\u624b\u4e4b\u5916\uff0c\u66f4\u77e5\u9053\u4e86\u591a\u8b8a\u591a\u5df4\u80fa\u9084\u662f\u8207\u8a18\u61b6\u3001\u7761\u7720\u4ee5\u53ca\u904b\u52d5\u611f\u7b49\u606f\u606f\u76f8\u95dc\u7684\u95dc\u9375\u64cd\u63a7\u624b\u3002\u5728\u79d1\u5b78\u6301\u7e8c\u4e0d\u65b7\u5730\u7406\u89e3\u4e2d\uff0c\u591a\u5df4\u80fa\u7684\u78ba\u5207\u6027\u8cea\u6301\u7e8c\u62d3\u5c55\u3001\u591a\u8b8a\u3002\u770b\u8457\u5979\u7d50\u69cb\u5f0f\u4e2d\u300cHo Ho\u300d\u7b11\u8457\uff08\u5716\u4e09\uff09\u7684\u6a23\u5b50\u4e0d\u7981\u8981\u8aaa\uff0c\u6108\u662f\u77ad\u89e3\u591a\u5df4\u80fa\uff0c\u591a\u5df4\u80fa\u6108\u662f\u4ee4\u4eba\u6210\u766e\u5462\uff01<\/p>\n<figure id=\"attachment_44047\" aria-describedby=\"caption-attachment-44047\" style=\"width: 800px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-44047 size-large\" src=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA3_AH_20240318-1024x576.png\" alt=\"\" width=\"800\" height=\"450\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA3_AH_20240318-1024x576.png 1024w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA3_AH_20240318-300x169.png 300w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA3_AH_20240318-768x432.png 768w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2024\/04\/DA3_AH_20240318.png 1280w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption id=\"caption-attachment-44047\" class=\"wp-caption-text\">\u5716\u4e09\uff1a\u591a\u5df4\u80fa\u5728\u4e0d\u540c\u6642\u671f\u7684\u7814\u7a76\u767c\u73fe\u5404\u6709\u4e0d\u540c\u7684\u4ee3\u8868\u4fe1\u865f\uff0c\u5982\u5feb\u6a02\u3001\u617e\u671b\u3001\u52d5\u6a5f\u76ee\u6a19\u7b49\uff5c\u4f86\u6e90\uff1a\u4f5c\u8005\u63d0\u4f9b<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<hr \/>\n<p><strong>\u53c3\u8003\u6587\u737b<\/strong><\/p>\n<ol>\n<li><a href=\"https:\/\/www.rigb.org\/explore-science\/explore\/blog\/what-dopamine\" target=\"_blank\" rel=\"noopener\">Collingwood, C., Apr.28.2023, \"What is dopamine?\", <em>The Royal Institution<\/em>.<\/a><\/li>\n<li><a href=\"https:\/\/pharmrev.aspetjournals.org\/content\/75\/1\/62\" target=\"_blank\" rel=\"noopener\">Channer, B., Matt, S. M., Nickoloff-Bybel, E. A., Pappa, V., Agarwal, Y., Wickman, J., &amp; Gaskill, P. J., 2023, \"Dopamine, immunity, and disease. <em>Pharmacological Reviews\"<\/em>, 75(1), 62-158.<\/a><\/li>\n<li><a href=\"https:\/\/www.cell.com\/trends\/neurosciences\/fulltext\/S0166-2236(07)00051-3\" target=\"_blank\" rel=\"noopener\">Bj\u00f6rklund, A., &amp; Dunnett, S. B., 2007, \"Fifty years of dopamine research.\", <em>Trends in Neurosciences<\/em>, 30(5), 185-187.<\/a><\/li>\n<li><a href=\"https:\/\/archive.org\/details\/theenochianmagickofdr.johndee.themostpowerfulsystemofmagickinitsoriginalunexpurg\/mode\/2up\">Internet Archive, The Enochian Magick Of Dr. John Dee. The Most Powerful System Of Magick In Its Original, Unexpurgated Form By Geoffrey James, ark:\/13960\/t2h78ww58<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0165017398000198\">Berridge, K. C., &amp; Robinson, T. E., 1998, \"What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?\",\u00a0<em>Brain Research Reviews<\/em>, 28(3), 309-369.<\/a><\/li>\n<li><a href=\"https:\/\/www.cell.com\/neuron\/fulltext\/S0896-6273(12)00941-5\" target=\"_blank\" rel=\"noopener\">Salamone, J. 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