{"id":42455,"date":"2023-06-22T18:00:11","date_gmt":"2023-06-22T10:00:11","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=42455"},"modified":"2023-07-04T14:37:49","modified_gmt":"2023-07-04T06:37:49","slug":"%e6%b2%92%e6%9c%89%e6%80%a7%e6%85%be%e5%97%8e%ef%bc%9f%e9%81%8b%e5%8b%95%e6%88%96%e8%a8%b1%e6%98%af%e6%9c%80%e5%a5%bd%e7%9a%84%e6%98%a5%e8%97%a5","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=42455","title":{"rendered":"\u6c92\u6709\u6027\u617e\u55ce\uff1f\u904b\u52d5\u6216\u8a31\u662f\u6700\u597d\u7684\u6625\u85e5"},"content":{"rendered":"

\u3010CASE \u5831\u79d1\u5b78\u3011\u65b0\u7cfb\u5217\u3001\u5168\u5c55\u958b\uff01<\/p>\n

\u4eba\u985e\u751f\u6d3b\u4e2d\u300c\u6027\u300d\u4e00\u76f4\u90fd\u5728\uff0c\u537b\u4e5f\u4e00\u76f4\u88ab\u63a9\u84cb\u3002\u4f60\u77e5\u9053\u55ce\uff1f\u300c\u6027\u300d\u7684\u5f71\u97ff\u529b\u9060\u6bd4\u4f60\u60f3\u7684\u9084\u8981\u5927\uff0c\u5b83\u6df1\u6df1\u5730\u5f71\u97ff\u4e86\u6211\u5011\u7684\u8eab\u5fc3\u9748\uff0c\u751a\u81f3\u662f\u81ea\u6211\u50f9\u503c\u3002\u7136\u800c\uff0c\u76ee\u524d\u793e\u6703\u4ecd\u666e\u904d\u907f\u514d\u8a0e\u8ad6\u76f8\u95dc\u8b70\u984c\u3002\u6211\u5011\u5e0c\u671b\u900f\u904e\u6027\u6559\u80b2\u7684\u7cfb\u5217\u6587\u7ae0\uff0c\u5206\u4eab\u6027\u79d1\u5b78\u7814\u7a76\u5167\u5bb9\u8207\u767c\u5c55\uff0c\u63d0\u4f9b\u516c\u958b\u4e14\u900f\u660e\u7684\u7ba1\u9053\uff0c\u8b93\u5927\u5bb6\u7372\u5f97\u6b63\u78ba\u7684\u6027\u76f8\u95dc\u77e5\u8b58\u3002\u7576\u6211\u5011\u7684\u6027\u77e5\u8b58\u8d8a\u8c50\u5bcc\uff0c\u9664\u4e86\u66f4\u77ad\u89e3\u81ea\u6211\uff0c\u4e5f\u589e\u52a0\u4fdd\u8b77\u81ea\u5df1\u7684\u80fd\u529b\uff0c\u4e26\u671f\u671b\u672a\u4f86\u5927\u5bb6\u53ef\u4ee5\u66f4\u6b63\u5411\u5730\u770b\u5f85\u6027\u7684\u8b70\u984c\u3002<\/p>\n

 <\/p>\n

\u672c\u7cfb\u5217\u6587\u7ae0\u70ba\u8868\u793a\u6027\u6559\u80b2\u4e4b\u76ee\u7684\uff0c\u90e8\u5206\u6027\u76f8\u95dc\u79d1\u5b78\u6587\u737b\u5716\u7247\u53ef\u80fd\u5177\u7537\u5973\u6027\u5668\u5b98\uff0c\u56e0\u6b64\uff0c\u672c\u7cfb\u5217\u6587\u7ae0\u6839\u64da\u300c\u5152\u7ae5\u53ca\u5c11\u5e74\u798f\u5229\u8207\u6b0a\u76ca\u4fdd\u969c\u6cd5\u300d\u898f\u5b9a\uff0c\u4e26\u4f9d\u7db2\u7ad9\u5206\u7d1a\u898f\u5b9a\u8655\u7406\u6bcf\u7bc7\u6587\u7ae0\u7684\u88f8\u9732(SB)\u72c0\u614b\u5206\u7d1a\uff0c\u4f9d\u5e8f\u70ba\u7121\u9632\u8b77\u6a5f\u5236<\/strong><\/span>\u3001\u8b66\u793a\u6a5f\u5236<\/strong><\/span>\u3001\u963b\u6514\u6a5f\u5236<\/strong><\/span>\u8207\u56b4\u683c\u5e74\u9f61\u9632\u8b77\u6a5f\u5236<\/strong><\/span>\u7b49\uff0c\u7686\u6703\u5728\u6bcf\u7bc7\u6587\u7ae0\u524d\u544a\u77e5\u8b80\u8005\u8a72\u7bc7\u6587\u7ae0\u4e4b\u5206\u7d1a\u7a0b\u5ea6\uff08\u672c\u6587\u5167\u5bb9\u5177\u6b63\u9762\u50f9\u503c\u4e14\u6b63\u9762\u50f9\u503c\u8207\u5448\u73fe\u5167\u5bb9\u7b26\u5408\u6bd4\u4f8b\uff09\uff0c\u8acb\u8a73\u7d30\u3001\u5b89\u5fc3\u5730\u95b1\u8b80\u76f8\u95dc\u8cc7\u8a0a\uff0c\u4e26\u914d\u5408\u4e0b\u65b9\u8aaa\u660e\u95b1\u89bd\u3002<\/p>\n

 <\/p>\n

\n

\u63d0\u9192\u60a8\uff0c\u672c\u7bc7\u6587\u7ae0\u96b8\u5c6c\u70ba \u7121\u9632\u8b77\u6a5f\u5236<\/span>\uff0c\u60a8\u5373\u5c07\u9032\u5165\u4e4b\u6587\u7ae0\u5177\u6b63\u5411\u610f\u7fa9\u4e14\u7121\u4efb\u4f55\u9650\u5236\u7d1a\u5167\u5bb9\uff0c\u5404\u5e74\u9f61\u5c64\u7686\u53ef\u95b1\u8b80\u672c\u7bc7\u6587\u7ae0\u3002<\/strong><\/p>\n<\/blockquote>\n

 <\/p>\n

\n

 <\/p>\n

\u79d1\u5b78\u7814\u7a76\u986f\u793a\uff0c\u9069\u5ea6\u7684\u904b\u52d5\u80fd\u5920\u523a\u6fc0\u5973\u6027\u7684\u8377\u723e\u8499\u7cfb\u7d71\uff0c\u589e\u52a0\u8840\u6d41\u91cf\u548c\u6d3b\u5316\u4ea4\u611f\u795e\u7d93\u7cfb\u7d71\uff0c\u9032\u800c\u6539\u5584\u6027\u617e\u548c\u6027\u529f\u80fd\uff0c\u4e26\u589e\u52a0\u6027\u559a\u8d77\u7684\u80fd\u529b\u3002\u6b64\u5916\uff0c\u904b\u52d5\u9084\u80fd\u6539\u5584\u8eab\u5fc3\u72c0\u614b\u3001\u6e1b\u8f15\u58d3\u529b\u548c\u7126\u616e\uff0c\u63d0\u9ad8\u81ea\u5c0a\u5fc3\uff0c\u9019\u4e9b\u6548\u679c\u90fd\u5c0d\u5973\u6027\u7684\u6027\u617e\u6709\u6b63\u9762\u7684\u5f71\u97ff\u3002\u76f8\u8f03\u65bc\u6cbb\u7642\u6027\u617e\u4f4e\u4e0b\u7684\u85e5\u7269\uff0c\u904b\u52d5\u662f\u4e00\u7a2e\u81ea\u7136\u4e14\u6709\u6548\u7684\u65b9\u6cd5\uff0c\u80fd\u66f4\u8b93\u5973\u6027\u91cd\u71c3\u6027\u617e\uff0c\u4e26\u7372\u5f97\u8eab\u5fc3\u9748\u5404\u65b9\u9762\u5168\u9762\u5730\u6539\u5584\u3002<\/strong><\/span><\/p>\n

\u64b0\u6587\uff5c\u8309\u8389\u5c0f\u5b78\u5802<\/strong><\/p>\n

\u5be9\u5b9a\uff5c\u81fa\u5927\u79d1\u5b78\u6559\u80b2\u767c\u5c55\u4e2d\u5fc3<\/strong><\/p>\n

\"\"<\/p>\n

\u5c0e\u81f4\u5973\u6027\u6027\u617e\u4f4e\u4e0b\u7684\u6210\u56e0\u8907\u96dc\uff0c\u9664\u4e86\u751f\u7406\u65b9\u9762\u7684\u5f71\u97ff\uff0c\u4f8b\u5982\u66f4\u5e74\u671f\u3001\u54fa\u4e73\u671f\u7b49\uff0c\u6027\u559a\u8d77\u80fd\u529b\u4e5f\u6703\u53d7\u5230\u5fc3\u7406\u56e0\u7d20\u7684\u5f71\u97ff\uff0c\u5305\u62ec\uff1a\u5fc3\u7406\u72c0\u614b\u3001\u548c\u4f34\u4fb6\u7684\u611f\u60c5\u72c0\u614b\u3001\u5c0d\u6027\u884c\u70ba\u7684\u614b\u5ea6\u6216\u4fe1\u5ff5\u3001\u8ca0\u9762\u7684\u6027\u53f2\u7b49\u3002<\/p>\n

 <\/p>\n

1998\u5e74\uff0c\u7531\u8f1d\u745e\u85e5\u5ee0\u88fd\u9020\u7684\u5a01\u800c\u92fc (Viagra) \u85e5\u7269\u554f\u4e16\uff0c\u4e0d\u50c5\u89e3\u6551\u4e86\u7121\u6578\u7684\u5a5a\u59fb\uff0c\u4e5f\u5e6b\u52a9\u4e86\u8a31\u591a\u7537\u6027\u91cd\u632f\u96c4\u98a8\uff0c\u6062\u5fa9\u81ea\u5c0a\u5fc3\u3002\u540c\u6a23\u5730\uff0c\u85e5\u7269\u7814\u767c\u4eba\u54e1\u5011\u4e5f\u81f4\u529b\u65bc\u767c\u660e\u6539\u5584\u5973\u6027\u6027\u617e\u4f4e\u4e0b\u7684\u85e5\u7269\uff0c\u76ee\u524d\u7f8e\u570b\u98df\u54c1\u548c\u85e5\u7269\u7ba1\u7406\u5c40 (FDA) \u5171\u6838\u51c6\u4e862\u7a2e\u85e5\u7269\uff0c\u5206\u5225\u662f2015\u5e74\u7684\u7684\u6c1f\u73ed\u8272\u6797 (Addyi)\uff0c\u548c2019\u5e74\u7684\u5e03\u96f7\u9ed8\u6d6a\u80bd (Vyleesi) \u3002<\/p>\n

 <\/p>\n

\u5e02\u552e\u7684\u6539\u5584\u5973\u6027\u6027\u617e\u4f4e\u4e0b\u85e5\u7269\u6709\u4ec0\u9ebc\u7f3a\u9ede\uff1f<\/span><\/strong><\/h6>\n

\u6c1f\u73ed\u8272\u6797\u70ba\u53e3\u670d\u85e5\u7269\uff0c\u4f7f\u7528\u6b64\u7a2e\u85e5\u7269\u9032\u884c\u6cbb\u7642\u7684\u5973\u6027\uff0c\u75c7\u72c0\u7372\u5f97\u6539\u5584\u7684\u6bd4\u4f8b\u7d04\u572830\uff5e55%\u5de6\u53f3\uff0c\u4e0d\u904e\u6b64\u7a2e\u85e5\u7269\u4f7f\u7528\u7684\u7f3a\u9ede\u70ba\u9700\u8981\u6bcf\u65e5\u670d\u7528\uff0c\u4e14\u7121\u6cd5\u7acb\u5373\u898b\u6548\uff0c\u6700\u9577\u751a\u81f3\u8981\u670d\u7528\u52308\u9031\u624d\u80fd\u770b\u5230\u6548\u679c\uff0c\u800c\u4e14\u670d\u7528\u5f8c\u5e38\u6703\u6709\u982d\u6688\u3001\u55dc\u7761\u3001\u75b2\u52de\u3001\u4f4e\u8840\u58d3\u7b49\u7684\u526f\u4f5c\u7528\u3002\u800c\u53e6\u4e00\u7a2e\u6cbb\u7642\u6027\u617e\u4f4e\u4e0b\u7684\u85e5\u7269\u2014\u2014\u5e03\u96f7\u9ed8\u6d6a\u80bd (Vyleesi) \u5fc5\u9808\u5728\u9032\u884c\u6027\u884c\u70ba\u524d\u81f3\u5c1145\u5206\u9418\u4ee5\u76ae\u4e0b\u6ce8\u5c04\u7684\u65b9\u5f0f\u7528\u85e5\u3002<\/p>\n

 <\/p>\n

\u5929\u7136\u7684\u5c1a\u597d\uff0c\u9664\u4e86\u85e5\u7269\u6cbb\u7642\u5916\uff0c\u4e5f\u8a66\u8a66\u770b\u904b\u52d5\u5427\uff01<\/span><\/strong><\/h6>\n

\u81ea\u4e8c\u5341\u4e16\u7d00\u4ee5\u4f86\uff0c\u79d1\u5b78\u5bb6\u767c\u73fe\u5c08\u696d\u7684\u5973\u6027\u904b\u52d5\u54e1\u6709\u6642\u6703\u9047\u5230\u300c\u904b\u52d5\u6027\u9589\u7d93\u300d\u7684\u75c7\u72c0\uff0c\u5f8c\u7d93\u7814\u7a76\u8b49\u660e\uff0c\u6b64\u75c7\u72c0\u8207\u5979\u5011\u9700\u8981\u9577\u671f\u9032\u884c\u9ad8\u5f37\u5ea6\u904b\u52d5\u7684\u5de5\u4f5c\u6027\u8cea\u6709\u95dc\uff0c\u4eba\u5011\u4e5f\u5c31\u9032\u800c\u5f97\u77e5\u904b\u52d5\u4f3c\u4e4e\u80fd\u5920\u523a\u6fc0\u5973\u6027\u7684\u8377\u723e\u8499\u3002\u4e0d\u904e\uff0c\u53ef\u5225\u62ff\u300c\u904b\u52d5\u6027\u9589\u7d93\u300d\u4f86\u7576\u4f5c\u4e0d\u904b\u52d5\u7684\u85c9\u53e3\u3002\u73fe\u4eca\u591a\u6578\u4eba\u7684\u5de5\u4f5c\u578b\u614b\u662f\u4ee5\u8fa6\u516c\u5ba4\u751f\u6d3b\u70ba\u4e3b\uff0c\u9577\u671f\u7f3a\u4e4f\u904b\u52d5\uff0c\u7576\u7136\u4e5f\u8f03\u5c11\u6703\u9047\u5230\u9019\u7a2e\u7279\u6b8a\u60c5\u6cc1\u3002\u800c\u4e14\u904b\u52d5\u7684\u597d\u8655\u9060\u5927\u65bc\u58de\u8655\uff0c\u4e0d\u50c5\u80fd\u5920\u9810\u9632\u548c\u6cbb\u7642\u8eab\u9ad4\u7684\u75be\u75c5\uff0c\u9084\u80fd\u6539\u5584\u58d3\u529b\u3001\u6182\u9b31\u548c\u7126\u616e\u8207\u5fc3\u8840\u7ba1\u75be\u75c5\u7b49\uff0c\u4f7f\u8eab\u5fc3\u9748\u7686\u7372\u5f97\u5168\u9762\u7684\u6539\u5584\u3002\u7576\u81ea\u5df1\u7684\u8eab\u5fc3\u72c0\u6cc1\u8d8a\u826f\u597d\u3001\u8eab\u9ad4\u5fc3\u50cf\u8d8a\u6eff\u610f\uff0c\u6027\u617e\u4e5f\u6703\u96a8\u4e4b\u800c\u4f86\u3002<\/p>\n

\u5728\u904e\u53bb20\u5e74\u4e2d\uff0c\u5df2\u7d93\u6709\u4e0d\u5c11\u6587\u737b\u63d0\u4f9b\u4e86\u5145\u8db3\u7684\u8b49\u64da\uff0c\u8b49\u660e\u9069\u5ea6\u7684\u904b\u52d5\u80fd\u5920\u6539\u5584\u5973\u6027\u7684\u6027\u554f\u984c\uff0c\u4e26\u63d0\u5347\u6027\u617e\u548c\u589e\u52a0\u6027\u559a\u8d77\u7684\u80fd\u529b\u3002\u5118\u7ba1\u6cbb\u7642\u5973\u6027\u6027\u617e\u4f4e\u4e0b\u7684\u85e5\u7269\u5df2\u6709\u5169\u6b3e\u554f\u4e16\uff0c\u4f46\u904b\u52d5\u662f\u4e00\u7a2e\u65e2\u81ea\u7136\u53c8\u4e0d\u7528\u82b1\u9322\u7684\u5973\u6027\u91cd\u71c3\u6027\u617e\u65b9\u6cd5\uff0c\u4f55\u6a02\u800c\u4e0d\u70ba\u5462\uff1f<\/p>\n

\u9019\u908a\u6211\u5011\u5148\u4f86\u77ad\u89e3\u4e00\u4e0b\u5973\u6027\u7684\u6027\u559a\u8d77\u751f\u7406\u6a5f\u5236\u3002<\/p>\n

\u25c6\u8840\u6d41\u8b8a\u5316\u589e\u52a0\u6027\u559a\u8d77\u7684\u80fd\u529b<\/strong><\/span><\/p>\n

\u8fa6\u516c\u5ba4\u751f\u6d3b\u5750\u592a\u4e45\u4e86\u55ce\uff1f\u8a72\u8d77\u4f86\u52d5\u4e00\u52d5\u56c9\uff01<\/p>\n

\u7576\u5973\u6027\u53d7\u5230\u6027\u523a\u6fc0\u6642\uff0c\u6027\u559a\u8d77\u6a5f\u5236\u6703\u4f7f\u751f\u6b96\u5668\u548c\u975e\u751f\u6b96\u5668\u7684\u8eab\u9ad4\u90e8\u4f4d\u7522\u751f\u8b8a\u5316\u3002\u751f\u6b96\u5668\u5340\u57df\uff0c\u6d41\u5411\u9670\u8482\u6d77\u7dbf\u9ad4\u548c\u9670\u5507\u52d5\u8108\u7684\u8840\u6d41\u91cf\u589e\u52a0\uff1b\u975e\u751f\u6b96\u5668\u5340\u57df\uff0c\u5982\u4e73\u982d\u3001\u76ae\u819a\uff0c\u6703\u51fa\u73fe\u4e73\u982d\u8b8a\u786c\u3001\u76ae\u819a\u958b\u59cb\u5192\u6c57\u3001\u5fc3\u8df3\u52a0\u5feb\u7b49\u8b8a\u5316\u3002\u7576\u9670\u9053\u58c1\u7684\u5e73\u6ed1\u808c\u9b06\u5f1b\u6642\uff0c\u6703\u4f7f\u5f97\u9670\u9053\u5ef6\u9577\u548c\u64f4\u5f35\u3001\u9aa8\u76c6\u8154\u589e\u52a0\u8840\u6d41\u91cf\u3001\u751f\u6b96\u5668\u5145\u8840\uff0c\u9020\u6210\u9670\u9053\u58c1\u6bdb\u7d30\u8840\u7ba1\u5167\u7684\u58d3\u529b\u589e\u52a0\uff0c\u4e26\u4e14\u8a98\u767c\u6f64\u6ed1\u7684\u8840\u6f3f\u7a7f\u904e\u9670\u9053\u4e0a\u76ae\u5230\u9054\u9670\u9053\u8868\u9762\uff0c\u5f62\u6210\u6db2\u6ef4\u8986\u84cb\u9670\u9053\u58c1\u3002\u800c\u6b64\u6642\u7684\u76ae\u819a\u548c\u4e73\u623f\u4e5f\u6703\u7372\u5f97\u5145\u8db3\u7684\u8840\u6db2\u4f9b\u61c9\u3002<\/p>\n

\u25c6\u4ea4\u611f\u795e\u7d93\u7cfb\u7d71\u6d3b\u5316 (sympathetic nervous system, SNS) \u589e\u52a0\u6027\u559a\u8d77\u7684\u80fd\u529b<\/strong><\/span><\/p>\n

\u4ea4\u611f\u795e\u7d93\u7cfb\u7d71\u8207\u6027\u559a\u8d77\u80fd\u529b\u7684\u95dc\u806f\uff0c\u53ef\u4ee5\u5f9e\u6182\u9b31\u75c7\u85e5\u7269\u7684\u526f\u4f5c\u7528\u4f86\u61c9\u8b49\u3002\u6240\u6709\u6297\u6182\u9b31\u85e5\u7269\u7684\u5e38\u898b\u526f\u4f5c\u7528\u90fd\u8207\u6027\u529f\u80fd\u6709\u95dc\uff0c\u5982\u6027\u9ad8\u6f6e\u6642\u9593\u5ef6\u9072\u3001\u6027\u559a\u8d77\u969c\u7919\u7b49\uff0c\u5e02\u552e\u7684\u6182\u9b31\u75c7\u85e5\u7269\u5927\u7d04\u670985%\u662f\u5c6c\u65bc\u8840\u6e05\u7d20-\u6b63\u814e\u4e0a\u817a\u7d20\u56de\u6536\u6291\u5236\u5291 (serotonin and noradrenaline reuptake inhibitors, SNRI) \u6216\u9078\u64c7\u6027\u8840\u6e05\u7d20\u56de\u6536\u6291\u5236\u5291 (selective serotonin reuptake inhibitors, SSRI)\uff0c\u800c\u76ee\u524d\u5df2\u7d93\u6709\u8a31\u591a\u7814\u7a76\u8b49\u5be6\uff0cSSRI\u7684\u529f\u80fd\u5305\u542b\u6291\u5236\u4ea4\u611f\u795e\u7d93\u7cfb\u7d71\u6d3b\u52d5\uff0c\u7531\u6b64\u6211\u5011\u5c31\u53ef\u4ee5\u63a8\u65b7\uff0c\u4ea4\u611f\u795e\u7d93\u7cfb\u7d71\u8207\u6027\u559a\u8d77\u6a5f\u5236\u606f\u606f\u76f8\u95dc\u3002<\/p>\n

Lorenz\u548cMeston\u57282012\u5e74\u66fe\u9032\u884c\u4e00\u9805\u76f8\u95dc\u7814\u7a76\uff0c\u53d7\u8a66\u8005\u70ba50\u540d\u5973\u6027\uff0c\u4ed6\u5011\u8acb\u9019\u4e9b\u53d7\u8a66\u8005\u5728\u670d\u7528SNRI\u6216SSRI\u85e5\u7269\u4e4b\u5f8c\uff0c\u4ee5\u6700\u5927\u5fc3\u7387\u768480%\u5728\u8dd1\u6b65\u6a5f\u4e0a\u8dd1\u6b65\u3002\u672c\u6b21\u5be6\u9a57\u7684\u53d7\u8a66\u8005\u5011\u5171\u88ab\u5340\u5206\u70ba3\u7d44\uff1a\u7121\u904b\u52d5\u7d44\uff08\u63a7\u5236\u7d44\uff09\u3001\u8dd1\u6b6520\u5206\u9418\u5f8c\u4f11\u606f5\u5206\u9418\u7d44\u3001\u8dd1\u6b6520\u5206\u9418\u5f8c\u4f11\u606f15\u5206\u9418\u7d44\u3002<\/p>\n

\u5f85\u4f11\u606f\u5f8c\uff0cLorenz\u548cMeston\u518d\u8acb\u53d7\u8a66\u8005\u5011\u89c0\u770b\u8272\u60c5\u5f71\u7247\uff0c\u4e26\u4f7f\u7528\u9670\u9053\u5149\u96fb\u9ad4\u7a4d\u63cf\u8a18\u5668\u8a18\u9304\u4e0b\u751f\u6b96\u5668\u6027\u559a\u8d77\u7684\u7a0b\u5ea6\uff0c\u4e5f\u4f7f\u7528\u554f\u5377\u6e2c\u91cf\u5fc3\u7406\u6027\u559a\u8d77\u7a0b\u5ea6\u3002\u5be6\u9a57\u7d50\u679c\u986f\u793a\uff1a\u5728\u7121\u904b\u52d5\u7d44\u4e2d\uff0c\u670d\u7528SSRIs\u7684\u5973\u6027\u7684\u751f\u6b96\u5668\u53cd\u61c9\u660e\u986f\u4f4e\u65bc\u670d\u7528SNRIs\u7684\u5973\u6027\uff1b\u4f46\u5728\u6027\u523a\u6fc0\u524d\u9032\u884c\u8dd1\u6b65\u935b\u7149\u7684\u5169\u7d44\uff0c\u5247\u751f\u6b96\u5668\u6027\u559a\u8d77\u53cd\u6620\u7686\u660e\u986f\u589e\u52a0\u3002\u5f8c\u7e8c\u7814\u7a76\u9084\u767c\u73fe\uff0c\u5982\u679c\u662f\u6027\u529f\u80fd\u969c\u7919\u66f4\u56b4\u91cd\u7684\u5973\u6027\uff0c\u5728\u904b\u52d5\u5f8c\u6027\u559a\u8d77\u7684\u5e45\u5ea6\u6703\u66f4\u5927\u3002<\/p>\n

\u6b64\u5be6\u9a57\u5c31\u66f4\u52a0\u8b49\u660e\u4e86\u6027\u559a\u8d77\u6a5f\u5236\u8207\u4ea4\u611f\u795e\u7d93\u7cfb\u7d71\u7684\u6d3b\u52d5\u6709\u95dc\u3002<\/p>\n

\"\"
\u904b\u52d5\u5c0d\u5973\u6027\u751f\u6b96\u5668\u6027\u559a\u8d77\u7684\u5f71\u97ff\uff5c\u4f86\u6e90\uff1aLorenz, T.A. and C.M. Meston, Acute exercise improves physical sexual arousal in women taking antidepressants<\/em>. Annals of Behavioral Medicine, 2012. 43(3): p. 352-361.<\/figcaption><\/figure>\n

\u25c6\u904b\u52d5\u523a\u6fc0\u9ad4\u5167\u6fc0\u7d20\uff0c\u6027\u617eUP UP<\/strong><\/span><\/p>\n

\u9069\u5ea6\u904b\u52d5\u88ab\u8b49\u5be6\u80fd\u5920\u523a\u6fc0\u591a\u7a2e\u8207\u5973\u6027\u6027\u617e\u6709\u95dc\u7684\u8377\u723e\u8499\u5728\u9ad4\u5167\u91cb\u653e\uff0c\u5e6b\u52a9\u589e\u52a0\u6027\u617e\u3001\u6539\u5584\u6027\u529f\u80fd\uff0c\u5305\u62ec\uff1a<\/p>\n

    \n
  1. \u50ac\u7522\u7d20 (oxytocin)\uff1a\u4fc3\u9032\u6027\u884c\u70ba\u7684\u63a5\u53d7\u548c\u7d50\u5408\u3002<\/li>\n
  2. \u50ac\u4e73\u7d20 (prolactin)\uff1a\u5f15\u8d77\u6027\u6eff\u8db3\u548c\u6027\u9ad8\u6f6e\u5f8c\u7de9\u89e3\u3002<\/li>\n
  3. \u96cc\u6fc0\u7d20 (estrogens)\uff1a\u96cc\u6fc0\u7d20\u589e\u5f37\u6027\u617e\u3001\u6027\u559a\u8d77\u3001\u611f\u89ba\u95be\u503c\u548c\u751f\u6b96\u52d5\u8108\u8840\u6d41\u3002<\/li>\n
  4. \u776a\u56fa\u916e (Testosterone)\uff1a\u901a\u5e38\u8207\u6027\u617e\u589e\u52a0\u6709\u95dc\uff0c\u6709\u52a9\u65bc\u555f\u52d5\u6027\u6d3b\u52d5\u3002<\/li>\n<\/ol>\n

     <\/p>\n

    \u770b\u5230\u9019\u88e1\uff0c\u59b3\u662f\u5426\u611f\u53d7\u5230\u4e86\u904b\u52d5\u7684\u7a2e\u7a2e\u597d\u8655\uff0c\u4e26\u4e14\u77ad\u89e3\u5b83\u80fd\u5920\u559a\u8d77\u4f60\u7684\u751f\u547d\u6d3b\u529b\u5462\uff1f\u4e0d\u8ad6\u662f\u9a0e\u8173\u8e0f\u8eca\u3001\u8dd1\u6b65\u9084\u662f\u505a\u745c\u73c8\uff0c\u53ea\u8981\u8b93\u8eab\u9ad4\u6d3b\u52d5\u8d77\u4f86\uff0c\u6027\u617e\u5c31\u80fd\u518d\u6b21\u56de\u6b78\u4f60\u7684\u8eab\u9ad4\uff01<\/p>\n

     <\/p>\n

    \n

    \u53c3\u8003\u6587\u737b<\/strong><\/p>\n

      \n
    1. Meston, C.M. and A.M. Stanton, Understanding sexual arousal and subjective\u2013genital arousal desynchrony in women. Nature Reviews Urology, 2019. 16(2): p. 107-120.<\/li>\n
    2. Clayton, A.H., L. Brown, and N.N. Kim, Evaluation of safety for flibanserin. Expert Opinion on Drug Safety, 2020. 19(1): p. 1-8.<\/li>\n
    3. Simon, J., A. Clayton, and N. Kim, Clinically meaningful benefit in women with hypoactive sexual desire disorder treated with flibanserin. Sex Med. 2022; 10 (1): 100476. 2021.<\/li>\n
    4. Genazzani, A.D., et al., Exercise and Stress-Related Amenorrhea, in Amenorrhea: Volume 10: Frontiers in Gynecological Endocrinology. 2023, Springer. p. 67-76.<\/li>\n
    5. Peluso, M.A.M. and L.H.S.G. De Andrade, Physical activity and mental health: the association between exercise and mood. Clinics, 2005. 60(1): p. 61-70.<\/li>\n
    6. Stanton, A.M., A.B. Handy, and C.M. Meston, The effects of exercise on sexual function in women. Sexual medicine reviews, 2018. 6(4): p. 548-557.<\/li>\n
    7. Berman, J.R., Physiology of female sexual function and dysfunction. International Journal of Impotence Research, 2005. 17(1): p. S44-S51.<\/li>\n
    8. Levin, R.J., The mechanisms of human female sexual arousal. Annual review of sex research, 1992. 3(1): p. 1-48.<\/li>\n
    9. Shores, M.M., et al., Short-term sertraline treatment suppresses sympathetic nervous system activity in healthy human subjects. Psychoneuroendocrinology, 2001. 26(4): p. 433-439.<\/li>\n
    10. Werneke, U., S. Northey, and D. Bhugra, Antidepressants and sexual dysfunction. Acta Psychiatrica Scandinavica, 2006. 114(6): p. 384-397.<\/li>\n
    11. Lorenz, T.A. and C.M. Meston, Acute exercise improves physical sexual arousal in women taking antidepressants. Annals of Behavioral Medicine, 2012. 43(3): p. 352-361.<\/li>\n
    12. Hilz, M.J. and R. Wang, Chapter 43 - Physiology and pathophysiology of female sexual function, in Primer on the Autonomic Nervous System (Fourth Edition), I. Biaggioni, et al., Editors. 2023, Academic Press. p. 247-252<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

      \u79d1\u5b78\u7814\u7a76\u986f\u793a\uff0c\u9069\u5ea6\u7684\u904b\u52d5\u80fd\u5920\u523a\u6fc0\u5973\u6027\u7684\u8377\u723e\u8499\u7cfb\u7d71\uff0c\u589e\u52a0\u8840\u6d41\u91cf\u548c\u6d3b\u5316\u4ea4\u611f\u795e\u7d93\u7cfb\u7d71\uff0c\u9032\u800c\u6539\u5584\u6027\u617e\u548c\u6027\u529f\u80fd\uff0c\u4e26\u589e\u52a0\u6027\u559a\u8d77\u7684\u80fd\u529b\u3002\u6b64\u5916\uff0c\u904b\u52d5\u9084\u80fd\u6539\u5584\u8eab\u5fc3\u72c0\u614b\u3001\u6e1b\u8f15\u58d3\u529b\u548c\u7126\u616e\uff0c\u63d0\u9ad8\u81ea\u5c0a\u5fc3\uff0c\u9019\u4e9b\u6548\u679c\u90fd\u5c0d\u5973\u6027\u7684\u6027\u617e\u6709\u6b63\u9762\u7684\u5f71\u97ff\u3002\u76f8\u8f03\u65bc\u6cbb\u7642\u6027\u617e\u4f4e\u4e0b\u7684\u85e5\u7269\uff0c\u904b\u52d5\u662f\u4e00\u7a2e\u81ea\u7136\u4e14\u6709\u6548\u7684\u65b9\u6cd5\uff0c\u80fd\u66f4\u8b93\u5973\u6027\u91cd\u71c3\u6027\u617e\uff0c\u4e26\u7372\u5f97\u8eab\u5fc3\u9748\u5404\u65b9\u9762\u5168\u9762\u5730\u6539\u5584\u3002<\/p>\n","protected":false},"author":20,"featured_media":42495,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6533,3293],"tags":[6715,6717,6640,6716,446],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2023\/06\/\u6c92\u6709\u6027\u617e\u55ce\uff1f\u904b\u52d5\u6216\u8a31\u662f\u6700\u597d\u7684\u6625\u85e5\u3002.png","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/42455"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=42455"}],"version-history":[{"count":9,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/42455\/revisions"}],"predecessor-version":[{"id":42590,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/42455\/revisions\/42590"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/42495"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=42455"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=42455"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=42455"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}