{"id":37932,"date":"2022-02-10T00:51:56","date_gmt":"2022-02-09T16:51:56","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=37932"},"modified":"2022-01-17T14:34:01","modified_gmt":"2022-01-17T06:34:01","slug":"%e9%80%a0%e8%a1%80%e5%b9%b9%e7%b4%b0%e8%83%9e%e8%b6%8a%e5%a4%a7%ef%bc%8c%e8%80%81%e5%8c%96%e9%80%9f%e5%ba%a6%e8%b6%8a%e5%bf%ab%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=37932","title":{"rendered":"\u9020\u8840\u5e79\u7d30\u80de\u8d8a\u5927\uff0c\u8001\u5316\u901f\u5ea6\u8d8a\u5feb\uff1f"},"content":{"rendered":"

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\"\"<\/a>
\u5716\u7247\u4f86\u6e90\uff1awww.motionelements.com\/<\/figcaption><\/figure>\n

\u64b0\u6587\uff0f\u9673\u6df5\u9293<\/strong><\/p>\n

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\u8a8d\u8b58\u9020\u8840\u5e79\u7d30\u80de<\/strong><\/span><\/p>\n

\u9020\u8840\u5e79\u7d30\u80de\uff08hematopoietic stem cell, HSC\uff09\u662f\u53ef\u4ee5\u5206\u5316\u51fa\u6240\u6709\u8840\u7403\u7684\u5e79\u7d30\u80de\uff0c\u540c\u6642\u5177\u6709\u8907\u88fd\u3001\u591a\u6f5b\u80fd\u6027\uff08multipotency\uff09\u53ca\u81ea\u6211\u66f4\u65b0\uff08self-renewal\uff09\u7684\u7279\u6027\uff0c\u662f\u5df2\u77e5\u4eba\u9ad4\u4e2d\u9ad4\u7a4d\u6700\u5c0f\u7684\u7d30\u80de\u4e4b\u4e00\u3002HSC\u5206\u5316\u51fa\u7684\u8840\u7403\u53ef\u4ee5\u5206\u6210\u9aa8\u9ad3\u7fa4\u7cfb\uff08myeloid lineage\uff09\u548c\u6dcb\u5df4\u7fa4\u7cfb\uff08lymphoid lineage\uff09\uff0c\u524d\u8005\u7684\u7d30\u80de\u5305\u542b\u6709\u7d05\u8840\u7403\u3001\u5de8\u6838\u6bcd\u7d30\u80de\uff08\u6210\u719f\u5f8c\u5f62\u6210\u8840\u5c0f\u677f\uff09\u3001\u55ae\u6838\u7403\uff08\u6210\u719f\u5f8c\u8b8a\u6210\u5de8\u566c\u7d30\u80de\uff09\u3001\u55dc\u4e2d\u6027\u767d\u8840\u7403\u3001\u55dc\u9e7c\u6027\u767d\u8840\u7403\u3001\u55dc\u9178\u6027\u767d\u8840\u7403\u53ca\u80a5\u5927\u7d30\u80de\u7b49\uff1b\u5f8c\u8005\u7684\u7d30\u80de\u5247\u6709\u6a39\u72c0\u7a81\u7d30\u80de\u3001T\u7d30\u80de\u3001B\u7d30\u80de\uff08\u6210\u719f\u5f8c\u8b8a\u6210\u6f3f\u7d30\u80de\uff09\u53ca\u81ea\u7136\u6bba\u624b\u7d30\u80de\u7b49\u3002<\/p>\n

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\u53c3\u8003\u8cc7\u6599<\/strong><\/p>\n

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  1. Lengefeld J, Cheng CW, Maretich P, Blair M, Hagen H, McReynolds MR, Sullivan E, Majors K, Roberts C, Kang JH, Steiner JD, Miettinen TP, Manalis SR, Antebi A, Morrison SJ, Lees JA, Boyer LA, Yilmaz \u00d6H, Amon A. Cell size is a determinant of stem cell potential during aging.<\/a> Cell size is a determinant of stem cell potential during aging.<\/a> Sci Adv. 2021 Nov 12;7(46):eabk0271. doi: 10.1126\/sciadv.abk0271. Epub 2021 Nov 12.<\/li>\n
  2. Rudolph KL. Stem cell aging. Mech Ageing Dev. 2021 Jan;193:111394. doi: 10.1016\/j.mad.2020.111394. Epub 2020 Nov 9..<\/li>\n
  3. De Winter G. Aging as Disease. Med Health Care Philos. 2015 May;18(2):237-43. doi: 10.1007\/s11019-014-9600-y.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

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