{"id":37305,"date":"2021-10-22T00:57:53","date_gmt":"2021-10-21T16:57:53","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=37305"},"modified":"2021-09-28T13:25:44","modified_gmt":"2021-09-28T05:25:44","slug":"%e8%aa%8d%e8%ad%98%e7%8b%82%e7%8a%ac%e7%97%85","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=37305","title":{"rendered":"\u8a8d\u8b58\u72c2\u72ac\u75c5"},"content":{"rendered":"

\u72c2\u72ac\u75c5\u75c5\u6bd2\u6703\u5728\u4eba\u985e\u548c\u5176\u4ed6\u54fa\u4e73\u52d5\u7269\u4e2d\u5f15\u8d77\u6025\u6027\u4e14\u81f4\u547d\u7684\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u611f\u67d3\uff0c\u85c9\u7531\u88ab\u611f\u67d3\u52d5\u7269\u7684\u54ac\u50b7\u6216\u6293\u50b7\u4e4b\u553e\u6db2\u50b3\u64ad\uff0c\u75c5\u6bd2\u5f9e\u611f\u67d3\u90e8\u4f4d\u6cbf\u8457\u795e\u7d93\u5143\u50b3\u64ad\u5230\u8166\u548c\u810a\u96a8\uff0c\u75c5\u6bd2\u5728\u6b64\u5927\u91cf\u8907\u88fd\u800c\u5c0e\u81f4\u75c7\u72c0\uff0c\u4e00\u65e6\u51fa\u73fe\u75c7\u72c0\uff0c\u9019\u7a2e\u75be\u75c5\u7684\u81f4\u6b7b\u7387\u5e7e\u4e4e\u662f100%\uff0c\u96d6\u7136\u72c2\u72ac\u75c5\u4e26\u672a\u5728\u5168\u4e16\u754c\u5ee3\u6cdb\u6d41\u884c\uff0c\u4f46\u5c0d\u4eba\u985e\u7684\u5065\u5eb7\u53ca\u751f\u5b58\u4ecd\u6709\u76f8\u7576\u7a0b\u5ea6\u7684\u5a01\u8105\u6027\u3002\u5728\u672c\u6587\uff0c\u6211\u5011\u5c07\u5f15\u9818\u8b80\u8005\u8a8d\u8b58\u72c2\u72ac\u75c5\u3001\u75c5\u6bd2\u7684\u81f4\u75c5\u6a5f\u8f49\u53ca\u5176\u767c\u75c5\u524d\u6cbb\u7642\u3001\u9810\u9632\u3002<\/strong><\/span><\/p>\n

\"\"
\u5716\u7247\u4f86\u6e90\uff1aPixabay<\/figcaption><\/figure>\n

\u64b0\u6587\uff5c\u9673\u6df5\u9293<\/strong><\/p>\n

\u4ec0\u9ebc\u662f\u72c2\u72ac\u75c5<\/strong><\/span><\/p>\n

\u72c2\u72ac\u75c5(Rabies) \u662f\u5168\u7403\u6027\u7684\u4eba\u755c\u5171\u901a\u75be\u75c5\uff0c\u52d5\u7269\u5bbf\u4e3b\u7bc4\u570d\u5341\u5206\u5ee3\u6cdb\u3002\u72c2\u72ac\u75c5\u75c5\u6bd2\u5f15\u8d77\u7684\u6025\u6027\u8166\u810a\u9ad3\u708e\uff0c\u4e3b\u8981\u85c9\u7531\u88ab\u53d7\u5230\u611f\u67d3\u7684\u52d5\u7269\u54ac\u50b7\u7684\u553e\u6db2\u800c\u50b3\u67d3\u7684\uff0c\u7d93\u904e\u6578\u9031\u6216\u66f4\u9577\u6642\u9593\u7684\u6f5b\u4f0f\u671f\u5f8c\uff0c\u53ef\u80fd\u6703\u51fa\u73fe\u5404\u7a2e\u524d\u9a45\u75c7\u72c0\uff0c\u901a\u5e38\u5728\u795e\u7d93\u75c7\u72c0\u51fa\u73fe\u5f8c\u5e7e\u4e4e\u5fc5\u7136\u6b7b\u4ea1\uff0c\u6b7b\u56e0\u90fd\u662f\u7531\u65bc\u4e2d\u6a1e\u795e\u7d93\uff08\u8166\u3001\u810a\u9ad3\uff09\u906d\u5230\u75c5\u6bd2\u7834\u58de\u3002<\/p>\n

\u72c2\u72ac\u75c5\u53ef\u5206\u70ba\u4ee5\u4e0b\u5169\u578b\uff1a(1)\u8166\u708e\uff08\u72c2\u8e81\uff09\u578b\uff08\u7d04\u4f5480%\uff09\uff1a\u4e3b\u8981\u75c7\u72c0\u662f\u553e\u6db2\u5206\u6ccc\u904e\u591a\uff0c\u6fc0\u52d5\u8207\u5e73\u975c\u5728\u4e00\u6bb5\u6642\u9593\u5167\u4ea4\u66ff\uff0c\u8207\u5168\u8eab\u6027\u89ba\u9192\u3001\u904e\u5ea6\u8208\u596e\u6216\u6050\u6c34\u7684\u767c\u4f5c\u6709\u95dc\uff0c\u5176\u4e2d\u75d9\u6523\u6d89\u53ca\u541e\u56a5\u6642\u54bd\u5589\u5438\u6c23\u808c\u6536\u7e2e\uff1b(2)\u9ebb\u75fa\uff08\u7671\u7613\uff09\u578b\uff08\u7d04\u4f5420%\uff09\uff1a\u7279\u5fb5\u662f\u9032\u884c\u6027\u904b\u52d5\u795e\u7d93\u5143\u7121\u529b\u53ca\u65e9\u671f\u7684\u808c\u7121\u529b\uff08\u8166\u708e\u578b\u4e26\u672a\u89c0\u5bdf\u5230\uff09\uff0c\u767c\u5c55\u5230\u660f\u8ff7\u548c\u6b7b\u4ea1\u7684\u6642\u9593\u8981\u6bd4\u8166\u708e\u578b\u72c2\u72ac\u75c5\u66f4\u9577\u3002<\/p>\n

\u75be\u75c5\u7684\u9032\u7a0b\u53ef\u5206\u6210\u6f5b\u4f0f\u671f\uff081~3\u500b\u6708\uff09\u3001\u521d\u671f\uff08\u524d\u9a45\u671f\uff0c2~10\u65e5\uff09\u3001\u4e2d\u671f\uff08\u75d9\u6523\u671f\uff0c1~3\u65e5\uff09\u53ca\u672b\u671f\uff08\u7671\u7613\u671f\uff0c6\u81f318\u5c0f\u6642\uff09\u3002\u5176\u4e2d\u8166\u708e\u72c2\u72ac\u75c5\u60a3\u8005\u9032\u5165\u4e2d\u671f\u5f8c\uff0c\u75c5\u6bd2\u5728\u4e2d\u6a1e\u795e\u7d93\u5167\u5927\u91cf\u7e41\u6b96\uff0c\u5404\u7a2e\u75c7\u72c0\u8f49\u8da8\u5f37\u70c8\u4e14\u51fa\u73fe\u56b4\u91cd\u75d9\u6523\u3001\u5e7b\u89ba\uff0c\u5c0d\u5916\u754c\u523a\u6fc0\u7684\u53cd\u61c9\u8b8a\u5f97\u66f4\u52a0\u660e\u986f\uff0c\u5c24\u5176\u662f\u5c0d\u6c34\u7684\u53cd\u61c9\uff0c\u6b64\u300c\u6050\u6c34\u300d\u8868\u73fe\u76f8\u7576\u591a\u5143\uff0c\u8209\u51e1\u300c\u559d\u6c34\u300d\u3001\u300c\u6d41\u6c34\u8072\u300d\u3001\u300c\u770b\u898b\u6c34\u300d\u7b49\uff0c\u6700\u5f8c\u53ef\u80fd\u5c0e\u81f4\u60a3\u8005\u54bd\u5589\u56b4\u91cd\u75d9\u6523\u800c\u7a92\u606f\u6b7b\u4ea1\uff0c\u6240\u4ee5\u72c2\u72ac\u75c5\u4fd7\u7a31\u6050\u6c34\u75c7\uff08hydrophobia\uff09\u3002<\/p>\n

\u72c2\u72ac\u75c5\u4e3b\u8981\u767c\u751f\u65bc\u975e\u6d32\u3001\u4e9e\u6d32\u3001\u62c9\u4e01\u7f8e\u6d32\u53ca\u4e2d\u6771\u7b49\uff0c\u4e16\u754c\u885b\u751f\u7d44\u7e54\uff08WHO\uff09\u4f30\u8a08\u6bcf\u5e74\u7d04\u670959000~ 61000\u500b\u6b7b\u4ea1\u75c5\u4f8b\u3002\u81fa\u7063\u96d6\u65bc2002\u30012012\u5e74\u53ca2013\u5e74\u5206\u5225\u6709\u4e00\u4f8b\u5883\u5916\u79fb\u5165\u7684\u75c5\u4f8b\uff0c\u4f46\u81ea1959\u5e74\u8d77\u4fbf\u4e0d\u518d\u6709\u4eba\u7684\u672c\u571f\u75c5\u4f8b\uff0c1961\u5e74\u5f8c\u4e0d\u518d\u6709\u52d5\u7269\u75c5\u4f8b\u3002\u5118\u7ba1\u5982\u6b64\uff0c\u884c\u653f\u9662\u8fb2\u696d\u59d4\u54e1\u6703\u65bc2013\u5e747\u6708\u8d77\u78ba\u8a8d\u570b\u5167\u91ce\u751f\u52d5\u7269\u611f\u67d3\u72c2\u72ac\u75c5\u6bd2\uff0c\u76ee\u524d\u570b\u5167\u75ab\u60c5\u50c5\u4fb7\u9650\u65bc\u9f2c\u737e\u53ca\u767d\u9f3b\u5fc3\u7b49\u91ce\u751f\u52d5\u7269\u3002<\/p>\n

\u72c2\u72ac<\/strong>\u75c5<\/strong>\u75c5\u6bd2\u7684\u81f4\u75c5\u6a5f\u8f49<\/strong><\/span><\/p>\n

\u72c2\u72ac\u75c5\u75c5\u6bd2\u70ba\u55ae\u80a1\u7684RNA\u75c5\u6bd2\uff0c\u5c6c\u65bc\u687f\u72c0\u75c5\u6bd2\u79d1\u4e4b\u72c2\u72ac\u75c5\u75c5\u6bd2\u5c6c\uff0c\u5165\u4fb5\u5bbf\u4e3b\u5f8c\u6703\u5c07\u812b\u68c4\u7684\u86cb\u767d\u8cea\u5916\u6bbc\u907a\u7559\u5728\u7d30\u80de\u5167\uff0c\u805a\u96c6\u5f62\u6210\u55dc\u9178\u6027\u9846\u7c92\u4e4b\u5167\u57fa\u5c0f\u9ad4\uff08Negri body\uff09\uff0c\u666e\u904d\u5b58\u5728\u8166\u90e8\u53ca\u810a\u9ad3\u795e\u7d93\u7d30\u80de\u5167\uff0c\u88ab\u8a8d\u70ba\u662f\u4e00\u7a2e\u8a3a\u65b7\u72c2\u72ac\u75c5\u7684\u91cd\u8981\u6307\u6a19\u3002\u72c2\u72ac\u75c5\u75c5\u6bd2\u611f\u67d3\u5f8c\u6703\u5148\u5728\u50b7\u53e3\u9644\u8fd1\u7684\u9aa8\u9abc\u808c\u7d30\u80de\u4e2d\u8907\u88fd\uff0c\u5728\u9178\u6027\u74b0\u5883\u4e0b\uff08pH < 6.0\uff09\uff0c\u75c5\u6bd2\u7684G\u86cb\u767d\u68d8\u7a81\uff08spike\uff09\u53ef\u8207\u9aa8\u9abc\u808c\u7d30\u80de\u819c\u83f8\u9e7c\u578b\u4e59\u91af\u81bd\u9e7c\u53d7\u9ad4\uff08nicotinic acetylcholine receptor\uff09\u7d50\u5408\uff0c\u8207\u7d30\u80de\u819c\u878d\u5408\u5f62\u6210\u5167\u566c\u5c0f\u6ce1\u9032\u5165\u7d30\u80de\u8cea\u5167\uff0c\u96a8\u5f8c\u9032\u884c\u812b\u6bbc\u3001\u8f49\u9304\u53ca\u8907\u88fd\u5f8c\uff0c\u85c9\u7531\u51fa\u82bd\uff08budding\uff09\u65b9\u5f0f\u91cb\u51fa\u75c5\u6bd2\uff0c\u518d\u7d93\u7531\u795e\u7d93\u808c\u8089\u4ea4\u63a5\u8655\u904b\u52d5\u7d42\u677f (motor end plates)\u9032\u5165\u8ef8\u7a81\u5f8c \u5feb\u901f\u5730\u4ee5\u6bcf\u59295-100 mm\u7684\u901f\u5ea6\u7d93\u904e\u9006\u795e\u7d93\u5143\u8ef8\u7a81\u50b3\u905e (retrograde axonal transport) \u4e0a\u884c\u4fb5\u5165\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\uff08\u8166\u53ca\u810a\u9ad3\uff09\u3002<\/p>\n

\u5728\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u4e2d\uff0c\u75c5\u6bd2\u7684\u50b3\u64ad\u66f4\u52a0\u8fc5\u901f\uff0c\u4f34\u96a8\u8457\u56b4\u91cd\u7684\u751f\u7406\u8b8a\u5316\u548c\u75c5\u7406\u73fe\u8c61\uff0c\u9020\u6210\u4e2d\u6a1e\u795e\u7d93\u5143\u58de\u6b7b\u53ca\u795e\u7d93\u81a0\u8cea\u7d30\u80de\u7684\u75c5\u8b8a\uff0c\u4fb5\u5165\u810a\u9ad3\u548c\u8166\u5e79\u6642\u5247\u6703\u5c0e\u81f4\u9ebb\u75fa\uff0c\u60a3\u8005\u6703\u5448\u73fe\u6c88\u9b31\u3001\u660f\u8ff7\u53ca\u547c\u5438\u7570\u5e38\uff0c\u6700\u5f8c\u6b7b\u4ea1\u3002<\/p>\n

\u611f\u67d3\u72c2\u72ac\u75c5\u75c5\u6bd2\u7684\u81f4\u6b7b\u7387\u6975\u9ad8\uff0c\u5c24\u5176\u662f\u672b\u671f\u9032\u7a0b\u6975\u5feb\uff0c\u75c5\u60a3\u901a\u5e38\u4e0d\u5230\u4e00\u5929\u5373\u6703\u6b7b\u4ea1\uff0c\u4f46\u5176\u8a73\u7d30\u539f\u56e0\u5c1a\u4e0d\u6e05\u695a\u3002<\/p>\n

\u5df2\u6709\u5be6\u9a57\u767c\u73fe\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u5728\u611f\u67d3\u72c2\u72ac\u75c5\u75c5\u6bd2\u5f8c\uff0c\u5e72\u64fe\u7d20\u3001\u7d30\u80de\u6fc0\u7d20\u53ca\u8da8\u5316\u56e0\u5b50\u7684\u8868\u73fe\u6703\u986f\u8457\u589e\u52a0\uff0c\u8a31\u591a\u5e72\u64fe\u7d20\u8a98\u5c0e\u7684\u8f49\u9304\u6c34\u5e73\u4ea6\u4e0a\u5347\uff0c\u5728\u795e\u7d93\u7d30\u80de\u4e2d\u8da8\u5316\u56e0\u5b50\u7684\u8868\u73fe\u589e\u52a0\u4fc3\u4f7f\u514d\u75ab\u7d30\u80de\uff08\u7279\u5225\u662fT\u7d30\u80de\uff09\u9032\u5165\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\uff0c\u7814\u7a76\u8b49\u64da\u986f\u793a\u76f4\u81f3\u75c5\u6bd2\u9032\u5165\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u5f8c\uff0c\u514d\u75ab\u7cfb\u7d71\u624d\u767c\u73fe\u6709\u75c5\u6bd2\u5165\u4fb5\u800c\u958b\u59cb\u7522\u751f\u53cd\u61c9\u3002\u7136\u800c\uff0c\u72c2\u72ac\u75c5\u75c5\u6bd2\u662f\u5982\u4f55\u9003\u812b\u5468\u570d\u7d44\u7e54\u7684\u514d\u75ab\u76e3\u7ba1\u5c1a\u4e0d\u660e\u78ba\uff0c\u6709\u53ef\u80fd\u662f\u5728\u611f\u67d3\u65e9\u671f\uff0c\u75c5\u6bd2\u7684\u8907\u88fd\u6c34\u5e73\u5f88\u4f4e\u800c\u4f7f\u514d\u75ab\u7cfb\u7d71\u7121\u6cd5\u5075\u6e2c\u5230\u75c5\u6bd2\u7684\u5b58\u5728\uff0c\u6216\u8005\u662f\u5468\u570d\u7684\u514d\u75ab\u6291\u5236\u6a5f\u5236\u53d7\u5230\u8a98\u767c\u800c\u672a\u80fd\u53ca\u6642\u555f\u52d5\u514d\u75ab\u53cd\u61c9\u4ee5\u5c0d\u6297\u5165\u4fb5\u7684\u75c5\u6bd2\u3002<\/p>\n

\u72c2\u72ac\u75c5\u7684\u767c\u75c5\u524d\u6cbb\u7642\u53ca\u9810\u9632<\/strong><\/span><\/p>\n

\u72c2\u72ac\u75c5\u75c5\u767c\u5f8c\u5e7e\u4e4e\u7121\u6cd5\u6cbb\u7642\uff0c\u6545\u9bae\u5c11\u6709\u95dc\u65bc\u75c5\u767c\u5f8c\u88ab\u6cbb\u7642\u597d\u7684\u500b\u6848\u5831\u5c0e\uff0c\u4ea6\u8fc4\u7121\u7d93\u904e\u81e8\u5e8a\u91ab\u5b78\u8b49\u5be6\u6210\u529f\u7684\u76f8\u95dc\u6848\u4f8b\u3002<\/p>\n

\u767c\u75c5\u524d\u7684\u6cbb\u7642\u53ef\u63a1\u7528\u63a5\u7a2e\u72c2\u72ac\u75c5\u75ab\u82d7\u7684\u65b9\u6cd5\uff0c\u6700\u4f73\u6642\u9593\u662f\u5728\u88ab\u54ac\u50b7\u5f8c24\u5c0f\u6642\u4e4b\u5167\uff0c\u56e0\u70ba\u75ab\u82d7\u8a98\u767cB\u6dcb\u5df4\u7d30\u80de\u7522\u751f\u6297\u9ad4\u7684\u901f\u5ea6\u8981\u5feb\u65bc\u72c2\u72ac\u75c5\u75c5\u6bd2\u7e41\u6b96\u548c\u7834\u58de\u7684\u901f\u5ea6\uff0c\u6240\u4ee5\u5373\u4f7f\u75c5\u6bd2\u5df2\u7d93\u5165\u4fb5\uff0c\u65bc\u767c\u4f5c\u524d\u63a5\u7a2e\u4ecd\u7136\u6709\u6548\u3002\u6b64\u5916\uff0c\u91ab\u5e2b\u53ef\u80fd\u6703\u8f14\u4ee5\u6ce8\u5c04\u72c2\u72ac\u75c5\u6297\u8840\u6e05\uff08\u901a\u5e38\u662f\u7528\u88ab\u611f\u67d3\u5f8c\u75ca\u7652\u7684\u99ac\u6216\u7f8a\u7684\u8840\u6db2\u88fd\u5099\u800c\u6210\uff09\u6216\u4f7f\u7528\u6297\u8840\u6e05\u6d78\u6f64\u50b7\u53e3\uff0c\u5118\u91cf\u6e1b\u5c11\u72c2\u72ac\u75c5\u75c5\u6bd2\u7684\u8ca0\u8f09\u91cf\uff0c\u722d\u53d6\u514d\u75ab\u53cd\u61c9\u7522\u751f\u7684\u6642\u9593\uff0c\u4f46\u82e5\u75c5\u6bd2\u5df2\u5165\u4fb5\u4e2d\u6a1e\u795e\u7d93\u800c\u767c\u75c5\uff0c\u7531\u65bc\u514d\u75ab\u7d30\u80de\u53d7\u5230\u8840\u8166\u5c4f\u969c\uff08blood brain barrier\uff09\u7684\u963b\u9694\u800c\u5f88\u96e3\u9032\u5165\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\uff0c\u56e0\u6b64\u60a3\u8005\u5373\u4f7f\u63a5\u53d7\u88ab\u52d5\u514d\u75ab\u7684\u6cbb\u7642\u4e5f\u5f88\u96e3\u633d\u56de\u751f\u547d\u3002<\/p>\n

\u767c\u75c5\u524d\u7684\u9810\u9632\u4ea6\u53ef\u4f7f\u7528\u63a5\u7a2e\u72c2\u72ac\u75c5\u75ab\u82d7\u7684\u65b9\u6cd5\uff0c\u75ab\u82d7\u7684\u88fd\u5099\u65b9\u6cd5\u5305\u62ec\u4f7f\u7528\u52d5\u7269\u8166\u7d44\u7e54\u57f9\u990a\u6216\u4eba\u985e\u4e8c\u500d\u9ad4\u7d30\u80de\u75ab\u82d7\uff08Human diploid cell vaccine, HDCV\uff09\u3002\u5229\u7528\u52d5\u7269\u8166\u7d44\u7e54\u751f\u7522\u7684\u75ab\u82d7\u50f9\u683c\u4fbf\u5b9c\uff0c\u4f46\u4eba\u9ad4\u514d\u75ab\u53cd\u61c9\u8f03\u5927\uff0c\u53ef\u80fd\u5f15\u767c\u8166\u708e\uff1bHDCV\u7d30\u80de\u57f9\u990a\u6280\u8853\u96e3\u5ea6\u8f03\u5927\uff0c\u6210\u672c\u4ea6\u8f03\u9ad8\u3001\u4e3b\u8981\u5957\u7528\u5728\u5df2\u958b\u767c\u570b\u5bb6\u3002\u7136\u800c\uff0c\u5be6\u65bd\u4eba\u985e\u767c\u75c5\u524d\u7684\u66b4\u9732\u5f8c\u9810\u9632 \uff08postexposure prophylaxis, PEP) \u548c\u901a\u904e\u5c0d\u52d5\u7269\u9032\u884c\u75ab\u82d7\u63a5\u7a2e\uff0c\u72c2\u72ac\u75c5\u662f\u53ef\u4ee5\u9810\u9632\u7684\u3002\u56e0\u70ba\u4eba\u985e\u767c\u75c5\u524d\u7684 PEP \u6210\u672c\u5f88\u9ad8\uff08\u6bcf\u5291 11-150 \u7f8e\u5143\uff09\u4e14\u901a\u5e38\u96e3\u4ee5\u7372\u5f97\uff0c\u6240\u4ee5\u72ac\u985e\u75ab\u82d7\u63a5\u7a2e\u662f\u964d\u4f4e\u4eba\u985e\u72c2\u72ac\u75c5\u767c\u75c5\u7387\u6700\u5177\u6210\u672c\u6548\u76ca\u548c\u53ef\u884c\u6027\u7684\u65b9\u6cd5\uff08\u5df2\u77e5\u72ac\u985e\u5c0e\u81f499% \u4ee5\u4e0a\u7684\u4eba\u985e\u75c5\u4f8b\uff09\u3002<\/p>\n

WHO\u548c\u5408\u4f5c\u5925\u4f34\u5df2\u5236\u5b9a\u4e86\u85c9\u7531\u63a7\u5236\u72ac\u985e\u72c2\u72ac\u75c5\uff0c\u9054\u6210\u52302030\u5e74\u5728\u5168\u7403\u6d88\u9664\u4eba\u985e\u72c2\u72ac\u75c5\u7684\u76ee\u6a19\u3002<\/p>\n

 <\/strong><\/p>\n

\u53c3\u8003\u8cc7\u6599<\/strong><\/p>\n

    \n
  1. Hemachudha T, Ugolini G, Wacharapluesadee S, Sungkarat W, Shuangshoti S, Laothamatas J. Human rabies: neuropathogenesis, diagnosis, and management.<\/a> Lancet Neurol. 2013 May;12(5):498-513. doi: 10.1016\/S1474-4422(13)70038-3.<\/li>\n
  2. Jackson AC. Rabies: a medical perspective.<\/a> Rev Sci Tech. 2018 Aug;37(2):569-580. doi: 10.20506\/rst.37.2.2825.<\/li>\n
  3. Fehlner-Gardiner C. Rabies control in North America - past, present and future.<\/a> Rev Sci Tech. 2018 Aug;37(2):421-437. doi: 10.20506\/rst.37.2.2812.<\/li>\n
  4. Brunker K, Mollentze N. Rabies Virus.<\/a>Trends Microbiol. 2018 Oct;26(10):886-887. doi: 10.1016\/j.tim.2018.07.001. Epub 2018 Jul 30.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

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