{"id":36245,"date":"2021-04-16T00:38:43","date_gmt":"2021-04-15T16:38:43","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=36245"},"modified":"2021-02-24T15:43:04","modified_gmt":"2021-02-24T07:43:04","slug":"%e5%ad%90%e5%ae%ae%e5%85%a7%e8%86%9c%e5%ae%b9%e5%8f%97%e6%80%a7%e6%aa%a2%e6%b8%ac%e5%9c%a8%e4%bf%83%e9%80%b2%e8%83%9a%e8%83%8e%e6%88%90%e5%8a%9f%e8%91%97%e5%ba%8a%e4%b8%8a%e7%9a%84%e4%bd%9c%e7%94%a8","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=36245","title":{"rendered":"\u5b50\u5bae\u5167\u819c\u5bb9\u53d7\u6027\u6aa2\u6e2c\u5728\u4fc3\u9032\u80da\u80ce\u6210\u529f\u8457\u5e8a\u4e0a\u7684\u4f5c\u7528"},"content":{"rendered":"

\u6210\u529f\u61f7\u5b55\u9664\u8207\u80da\u80ce\u672c\u8cea\u6709\u5bc6\u5207\u95dc\u4fc2\u5916\uff0c\u5b50\u5bae\u5167\u819c\u72c0\u6cc1\u4ea6\u70ba\u91cd\u8981\u7684\u4e00\u74b0\u3002\u8a66\u7ba1\u5b30\u5152\u7642\u7a0b\u4e2d\u6e96\u5099\u690d\u5165\u80da\u80ce\u524d\uff0c\u9664\u4e86\u5b89\u6392\u8f38\u5375\u7ba1\u651d\u5f71\u3001\u5b50\u5bae\u93e1\u53ca\u81ea\u9ad4\u514d\u75ab\u7be9\u6aa2\u4ee5\u78ba\u8a8d\u8457\u5e8a\u74b0\u5883\u5916\uff0c\u9084\u9700\u8981\u5229\u7528\u5b50\u5bae\u5167\u819c\u5bb9\u53d7\u6027\u6aa2\u6e2c\uff08ERA\uff09\u4ee5\u9078\u64c7\u6700\u4f73\u6642\u9593\u9ede\u4f86\u300c\u7cbe\u6e96\u690d\u5165\u300d\u80da\u80ce\uff0c\u4fc3\u6210\u8a66\u7ba1\u5b30\u5152\u6210\u529f\u7387\u7684\u986f\u8457\u589e\u52a0\u3002\u6211\u5011\u5728\u672c\u6587\u5c07\u4ecb\u7d39\u8a66\u7ba1\u5b30\u5152\u6280\u8853\u7684\u5b50\u5bae\u5167\u819c\u5bb9\u53d7\u6027\u6aa2\u6e2c\uff0c\u5982\u4f55\u85c9\u7531\u627e\u5230\u500b\u4eba\u6700\u9069\u5408\u7684\u8457\u5e8a\u7a97\u671f\uff0c\u4ee5\u5354\u52a9\u53d7\u5230\u4e0d\u5b55\u75c7\u56f0\u64fe\u7684\u592b\u59bb\u63d0\u5347\u6210\u529f\u61f7\u5b55\u7684\u6a5f\u6703\u3002<\/strong><\/span><\/p>\n

\"\"
\u5716\u7247\u4f86\u6e90: Pixabay<\/figcaption><\/figure>\n

\u64b0\u6587\uff5c\u9673\u6df5\u9293<\/strong><\/p>\n

\u5b50\u5bae\u5167\u819c\u5bb9\u53d7\u6027\u6aa2\u6e2c<\/strong>\uff08<\/strong>Endometrial receptivity analysis<\/strong>, ERA<\/strong>\uff09<\/strong><\/span><\/p>\n

\u5728\u4eba\u5de5\u8f14\u52a9\u751f\u6b96\u6280\u8853\u4e2d\uff0c\u80da\u80ce\u54c1\u8cea\u53ca\u5b50\u5bae\u5167\u819c\u5bb9\u53d7\u6027\u662f\u80da\u80ce\u690d\u5165\u6210\u529f\u7684\u5169\u5927\u95dc\u9375\u8981\u7d20\u3002\u81e8\u5e8a\u4e0a\u6642\u5e38\u6709\u5df2\u63a5\u53d7\u8a66\u7ba1\u5b30\u5152\u7642\u7a0b\uff0c\u4e26\u690d\u5165\u7d93\u80da\u80ce\u690d\u5165\u524d\u67d3\u8272\u9ad4\u7be9\u6aa2\uff08preimplantation genetic screening\uff09\u78ba\u8a8d\u67d3\u8272\u9ad4\u6b63\u5e38\u7684\u80da\u80ce\uff0c\u4ecd\u672a\u80fd\u6210\u529f\u61f7\u5b55\u7684\u4f8b\u5b50\u3002\u56e0\u6b64\uff0c\u8a66\u7ba1\u5b30\u5152\u7642\u7a0b\u5728\u690d\u5165\u80da\u80ce\u524d\u6703\u5148\u9032\u884c\u5b50\u5bae\u8154\u93e1\u6aa2\u67e5\u53ca\u5167\u819c\u539a\u5ea6\u6aa2\u6e2c\uff08endometrium lining\uff09\uff0c\u4f46\u591a\u504f\u5411\u65bc\u5de8\u89c0\u6aa2\u6e2c\uff0c\u6709\u95dc\u80da\u80ce\u8457\u5e8a\u7684\u5fae\u89c0\u6a5f\u5236\u53ca\u5206\u5b50\u6aa2\u6e2c\uff0c\u4ecd\u7f3a\u4e4f\u5ba2\u89c0\u4e14\u79d1\u5b78\u7684\u8a3a\u65b7\u3002<\/p>\n

\u5b50\u5bae\u5167\u819c\u70ba\u61f7\u5b55\u671f\u9593\u80da\u80ce\u8457\u5e8a\u8207\u767c\u80b2\u4e4b\u8655\uff0c\u5728\u6bcf\u500b\u6708\u7d93\u9031\u671f\u50c5\u6709\u4e00\u6bb5\u7279\u5225\u6642\u671f\uff0c\u4ea6\u5373\u7576\u8457\u5e8a\u7a97\uff08window of implantation\uff09\u6253\u958b\u7684\u6642\u5019\uff0c\u624d\u5177\u6709\u63a5\u53d7\u80da\u80ce\u8457\u5e8a\u7684\u80fd\u529b\uff0c\u5176\u4e2d\u7d0470% \u7684\u4eba\u662f\u5728\u6392\u5375\u5f8c5-7\u5929\uff08\u6708\u7d93\u5468\u671f\u7b2c19-21\u5929\uff09\u958b\u555f\u8457\u5e8a\u7a97\uff0c\u800c\u7d0430% \u7684\u4eba\u4e26\u4e0d\u5728\u6b64\u7bc4\u570d\u5167\uff08\u975e\u6a19\u6e96\u7a97\u671f\uff09\uff0c\u9069\u7576\u7684\u8457\u5e8a\u7a97\u6642\u9593\u6703\u63d0\u524d\u6216\u5ef6\u5f8c1-2\u5929\u3002\u8457\u5e8a\u7a97\u671f\u4e4b\u5b50\u5bae\u5167\u819c\u7d30\u80de\u5f62\u614b\u3001\u67b6\u69cb\u8207\u529f\u80fd\u5747\u767c\u751f\u8b8a\u5316\uff0c\u5176\u4e2d\u4ee5\u5b50\u5bae\u4e0a\u76ae\u7d30\u80de\u7684\u9802\u7aef\u7d30\u80de\u819c\u4e0a\u7684\u7a81\u8d77 (pinopode) \u5f62\u6210\u6700\u5177\u6307\u6a19\u6027\uff0c\u5728\u5404\u7a2e\u6fc0\u7d20\uff08hormone\uff09\u3001\u751f\u9577\u56e0\u5b50\u3001\u9ecf\u9644\u56e0\u5b50\u53ca\u7d30\u80de\u6fc0\u7d20\uff08cytokine\uff09\u8907\u96dc\u7684\u4ea4\u4e92\u8abf\u7bc0\u4e0b\uff0c\u56ca\u80da\uff08blastocyst\uff09\u6703\u8207\u5b50\u5bae\u5167\u819c\u76f8\u4e92\u8b58\u5225\uff0c\u4e26\u9032\u884c\u5b9a\u4f4d\u3001\u9ecf\u9644\u800c\u690d\u5165\u4e0a\u76ae\u7d30\u80de\u5c64\uff0c\u6700\u5f8c\u6210\u529f\u8457\u5e8a\u65bc\u5b50\u5bae\u5167\u819c\u3002\u7531\u65bc\u8457\u5e8a\u7a97\u671f\u6642\u9593\u5341\u5206\u77ed\u66ab\uff0c\u6240\u4ee5\u627e\u51fa\u9069\u7576\u7684\u8457\u5e8a\u7a97\u671f\u5341\u5206\u91cd\u8981\u3002<\/p>\n

ERA\u662f\u5b50\u5bae\u5167\u819c\u5728\u53d7\u5230\u5916\u6e90\u6027\u9ec3\u9ad4\u7d20\u6d78\u6f64\u7684\u689d\u4ef6\u4e0b\uff0c\u7d93\u63a1\u6a23\u5b50\u5bae\u5167\u819c\u7d30\u80de\u5f8c\uff0c\u4f7f\u7528\u6b21\u4e16\u4ee3\u57fa\u56e0\u5b9a\u5e8f\uff08next generation sequencing\uff09\u5206\u6790\u8d85\u904e300\u7a2e\u8207\u5b50\u5bae\u5167\u819c\u5bb9\u53d7\u6027\u76f8\u95dc\u7684\u57fa\u56e0\uff0c\u6aa2\u6e2c\u51fa\u6700\u9069\u5408\u690d\u5165\u80da\u80ce\u7684\u6642\u9593\uff0c\u800c\u7814\u7a76\u5831\u544a\u5df2\u6307\u51fa\u932f\u8aa4\u7684\u80da\u80ce\u690d\u5165\u6642\u9593\u662f\u9020\u6210\u53cd\u8986\u6027\u80da\u80ce\u8457\u5e8a\u5931\u6557 (repeated implantation failure) \u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\u3002\u901a\u5e38ERA\u5831\u544a\u6703\u6709\u5bb9\u53d7\u671f (Receptive)\u53ca\u975e\u5bb9\u53d7\u671f (Non-receptive)\u5169\u7a2e\u7d50\u679c\uff1a\u82e5\u6aa2\u6e2c\u7d50\u679c\u986f\u793a\u70ba\u5bb9\u53d7\u671f\uff0c\u8868\u793a\u8457\u5e8a\u7a97\u671f\u662f\u63a1\u6aa2\u7576\u65e5\uff0c\u5efa\u8b70\u5728\u7528\u85e5\u689d\u4ef6\u8207\u6aa2\u9ad4\u63a1\u96c6\u76f8\u540c\u7684\u72c0\u614b\u4e0b\u690d\u5165\u80da\u80ce\uff1b\u82e5\u6aa2\u6e2c\u7d50\u679c\u986f\u793a\u70ba\u975e\u5bb9\u53d7\u671f\uff0c\u8868\u793a\u63a1\u6aa2\u6642\u9593\u4e26\u975e\u5b50\u5bae\u7684\u8457\u5e8a\u7a97\u671f\uff0c\u9808\u5229\u7528\u5927\u6578\u64da\u9032\u884c\u8a08\u7b97\uff0c\u65b9\u80fd\u5f97\u5230\u771f\u6b63\u7684\u8457\u5e8a\u7a97\u671f\uff0c\u7528\u4ee5\u9810\u6e2c\u80da\u80ce\u690d\u5165\u7684\u500b\u4eba\u5316\u6700\u4f73\u6642\u9593\u9ede\u3002\u8457\u5e8a\u6642\u671f\u53ef\u5206\u6210\u4e0b\u5217\u4e09\u500b\uff1a<\/p>\n

    \n
  1. \u8457\u5e8a\u671f\uff08Receptive\uff09\uff1a\u4ea6\u5373\u9069\u7576\u8457\u5e8a\u7a97\u671f\uff0c\u63a1\u6a23\u6642\u9593\u5373\u70ba\u5b50\u5bae\u5167\u819c\u63a5\u53d7\u671f\uff0c\u53ef\u4f9d\u64da\u6aa2\u6e2c\u7d50\u679c\u7acb\u5373\u5b89\u6392\u80da\u80ce\u690d\u5165\u3002<\/li>\n
  2. \u524d\u8457\u5e8a\u671f\uff08\u904e\u65e9\uff09\uff08Pre-receptive\uff09\uff1a\u63a1\u6a23\u6642\u9593\u5728\u8457\u5e8a\u7a97\u958b\u555f\u4e4b\u524d\uff0c\u690d\u5165\u9031\u671f\u9808\u5ef6\u9577\u9ec3\u9ad4\u7d20\u670d\u7528\u6642\u9593\u53ca\u9072\u5ef6\u690d\u5165\u80da\u80ce\u3002<\/li>\n
  3. \u5f8c\u8457\u5e8a\u671f\uff08\u904e\u665a\uff09\uff08Post-receptive\uff09\uff1a\u63a1\u6a23\u6642\u9593\u5728\u8457\u5e8a\u7a97\u958b\u555f\u4e4b\u5f8c\uff0c\u690d\u5165\u9031\u671f\u9808\u7e2e\u77ed\u9ec3\u9ad4\u7d20\u670d\u7528\u6642\u9593\u53ca\u63d0\u65e9\u690d\u5165\u80da\u80ce\u3002<\/li>\n<\/ol>\n

    \u9069\u5408\u9032\u884cERA\u7684\u5973\u6027\u5305\u62ec\u501f\u5375\u8005\u300135 \u6b72\u4ee5\u4e0b\u690d\u5165\u4e00\u6b21\u672a\u61f7\u5b55\u8005\u3001\u5e74\u9f61\u8d85\u904e43\u6b72\u8005\u53ca\u76f8\u95dc\u6aa2\u67e5\uff08\u5982\u8f38\u5375\u7ba1\u9020\u5f71\u3001\u5b50\u5bae\u93e1\u6aa2\u67e5\u53ca\u81ea\u9ad4\u514d\u75ab\u8840\u6db2\u6aa2\u6e2c\uff09\u7686\u6b63\u5e38\uff0c\u4f46\u591a\u6b21\u690d\u5165\u67d3\u8272\u9ad4\u6b63\u5e38\u56ca\u80da\u672a\u61f7\u5b55\u8005\u3002<\/p>\n

    ERA<\/strong>\u7684\u7cfb\u7d71\u6027\u56de\u9867\uff08<\/strong>systematic review<\/strong>\uff09\u53ca\u7d9c\u5408\u5206\u6790\uff08<\/strong>meta-analysis<\/strong>\uff09<\/strong><\/span><\/p>\n

    \u57282019\u5e74\uff0c\u82f1\u570b\u7814\u7a76\u4eba\u54e1\u6b78\u7d0d\u4e86163\u9805\u7e3d\u9ad4\u8cea\u91cf\u4e2d\u7b49\u7684\u7814\u7a76\uff0888834\u540d\u5973\u6027\uff09\uff0c\u5176\u4e2d96\u9805\u7d0d\u5165\u7d9c\u5408\u5206\u6790\uff0c<\/strong>\u76ee\u7684\u662f\u6aa2\u8996\u89c0\u5bdf\u6027\u7814\u7a76\uff08observational study\uff09\u7684\u8b49\u64da\uff0c\u9019\u4e9b\u8b49\u64da\u652f\u6301\u5c07\u5b50\u5bae\u5167\u819c\u63a5\u53d7\u6a19\u8a18\u7269\uff08endometrial receptivity marker\uff09\u4f5c\u70ba\u5e0c\u671b\u61f7\u5b55\u5a66\u5973\u7684\u598a\u5a20\u7d50\u5c40\u7684\u9810\u5f8c\u56e0\u7d20\uff0c\u4ee5\u5e6b\u52a9\u91ab\u751f\u9078\u64c7\u6700\u6709\u7528\u7684\u6a19\u8a18\u7269\uff0c\u4e26\u9032\u4e00\u6b65\u63d0\u4f9b\u8a0a\u606f\u3002\u4ed6\u5011\u5206\u5225\u5206\u6790\u5728\u81ea\u7136\u53d7\u5b55\uff08natural conception\uff09\u3001\u4eba\u5de5\u6388\u7cbe\uff08intrauterine insemination, IUI<\/em>\uff09\u53ca<\/em>\u9ad4\u5916\u53d7\u7cbe\uff08in vitro fertilization, IVF\uff09\u7684\u689d\u4ef6\u4e0b\uff0c\u5229\u7528\u8d85\u97f3\u6ce2\u3001\u5b50\u5bae\u5167\u819c\u6d3b\u6aa2\uff08biopsy\uff09\u3001\u5b50\u5bae\u5167\u819c\u7a4d\u6db2\u62bd\u5438\uff08fluid aspirate\uff09\u548c\u5b50\u5bae\u93e1\u6aa2\u67e5\uff08hysteroscopy\uff09\u4f86\u8a55\u4f30\u7684\u5404\u7a2e\u5b50\u5bae\u5167\u819c\u63a5\u53d7\u6a19\u8a18\u7269\uff0c\u767c\u73fe\u5728\u81e8\u5e8a\u61f7\u5b55\u548c\u5404\u7a2e\u5b50\u5bae\u5167\u819c\u63a5\u53d7\u6a19\u8a8c\u7269\uff08\u5982\u5b50\u5bae\u5167\u819c\u539a\u5ea6\u3001\u5b50\u5bae\u5167\u819c\u6a21\u5f0f\u3001\u591a\u666e\u52d2\u6307\u6578\u3001\u5b50\u5bae\u5167\u819c\u6ce2\u72c0\u6d3b\u6027\u53ca\u5404\u7a2e\u5206\u5b50\uff09\u4e4b\u9593\u6709\u95dc\u806f\u6027\uff0c\u9019\u4e9b\u6a19\u8a18\u7269\u9810\u6e2c\u81e8\u5e8a\u598a\u5a20\u7684\u80fd\u529b\u8f03\u5f31\uff0c\u7121\u6cd5\u5728\u81e8\u5e8a\u4e0a\u61c9\u7528\uff0c\u4f46\u6709\u5e7e\u9805\u73fe\u4ee3\u5206\u5b50\u6e2c\u8a66\u7684\u7d50\u679c\u4ee4\u4eba\u9f13\u821e\uff0c\u96d6\u5c1a\u5f85\u9032\u4e00\u6b65\u7684\u6578\u64da\u3002\u5206\u6790\u5f8c\u7684\u6e2c\u8a66\u6982\u7387\u53ef\u7528\u65bc\u81e8\u5e8a\u4e0a\u7ba1\u7406\u592b\u59bb\u5728\u751f\u80b2\u6cbb\u7642\uff08IUI\u548cIVF\uff09\u671f\u9593\u7684\u671f\u671b\uff0c\u5b50\u5bae\u5167\u819c\u7684\u5bb9\u53d7\u6027\u88ab\u8996\u70ba\u4e8c\u5206\u7d50\u679c\uff08\u5b58\u5728\u6216\u4e0d\u5b58\u5728\uff09\uff0c\u4f46\u662f\u5728\u8457\u5e8a\u7a97\u671f\u61c9\u5b58\u5728\u5404\u7a2e\u6c34\u5e73\uff08level\uff09\u7684\u5b50\u5bae\u5167\u819c\u7684\u63a5\u53d7\u5ea6\uff0c\u5982\u4e0d\u540c\u7684\u8f49\u9304\u7d44\u7279\u5fb5\uff08transcriptomic signature\uff09\u53ef\u4ee5\u4ee3\u8868\u4e0d\u540c\u6c34\u5e73\u7684\u63a5\u53d7\u5ea6\uff0c\u9019\u8207\u4e0d\u540c\u7684\u61f7\u5b55\u7d50\u5c40\u5177\u76f8\u95dc\u6027\u3002\u751f\u7269\u6a19\u8a8c\u7269\uff08biomarker\uff09\u7684\u6975\u503c\uff08\u8207\u5e73\u5747\u503c\u76f8\u53cd\uff09\u53ef\u80fd\u5177\u6709\u91cd\u5927\u7684\u9810\u5f8c\u548c\u8a3a\u65b7\u610f\u7fa9\uff0c\u4f46\u672a\u5728\u5e73\u5747\u503c\u4e2d\u986f\u73fe\u51fa\u4f86\u3002\u56e0\u6b64\uff0c\u4ed6\u5011\u5efa\u8b70\u63a1\u7528\u751f\u7269\u6a19\u8a8c\u7269\u6c34\u5e73\u7684\u5206\u985e\u7d50\u679c\uff08outcomes by categories of biomarker levels\uff09\uff0c\u800c\u975e\u81e8\u5e8a\u7d50\u679c\u7d44\u4e2d\u751f\u7269\u6a19\u8a8c\u7269\u6c34\u5e73\u7684\u5e73\u5747\u503c\uff08mean\uff09\u3002<\/p>\n

    \u7d50\u8ad6<\/strong><\/p>\n

    \u65e9\u671f\u751f\u6b96\u8870\u7aed\uff08early reproductive failure\uff09\u662f\u598a\u5a20\u671f\u7684\u6700\u5e38\u898b\u4f75\u767c\u75c7\uff08complication\uff09\uff0c\u53ea\u670930\uff05 \u7684\u61f7\u5b55\u9054\u5230\u6d3b\u7522\u3002\u6210\u529f\u7684\u61f7\u5b55\u53d6\u6c7a\u65bc\u80da\u80ce\u690d\u5165\u7684\u9069\u7576\u6642\u9593\u9ede\uff0c\u9019\u500b\u904e\u7a0b\u6d89\u53ca\u5b50\u5bae\u5167\u819c\u548c\u56ca\u80da\u4e4b\u9593\u7684\u76f8\u4e92\u4f5c\u7528\u3002\u64da\u4f30\u8a08\uff0c\u80da\u80ce\u672c\u8cea\u4e0a\u7684\u7f3a\u9677\u7d04\u4f54\u690d\u5165\u5931\u6557\u6a5f\u7387\u7684\u4e09\u5206\u4e4b\u4e00\uff0c\u800c\u5b50\u5bae\u5167\u819c\u7684\u63a5\u53d7\u80fd\u529b\u6b20\u4f73\u53ca\u80da\u80ce\uff0d\u5b50\u5bae\u5167\u819c\u7684\u4ea4\u4e92\u4f5c\u7528\u6539\u8b8a\u5247\u7d04\u4f54\u5176\u9918\u7684\u4e09\u5206\u4e4b\u4e8c\uff0c\u800c\u8fd1\u5e74ERA\u7684\u666e\u904d\u4f7f\u7528\u5df2\u986f\u8457\u63d0\u5347\u8a66\u7ba1\u5b30\u5152\u80da\u80ce\u8457\u5e8a\u7684\u6210\u529f\u6a5f\u7387\u3002\u5b50\u5bae\u5167\u819c\u7684\u5bb9\u53d7\u6027\u4e00\u76f4\u662f\u904e\u53bb\u591a\u5e74\u4f86\u5ee3\u6cdb\u7814\u7a76\u7684\u91cd\u9ede\uff0c\u4f7f\u4eba\u5011\u5c0d\u8207\u80da\u80ce\uff0d\u5b50\u5bae\u5167\u819c\u7684\u4ea4\u4e92\u4f5c\u7528\u6a5f\u5236\u548c\u690d\u5165\u76f8\u95dc\u7684\u904e\u7a0b\u6709\u6df1\u5165\u7684\u4e86\u89e3\uff0c\u4f46\u5c07\u9019\u7a2e\u7406\u89e3\u8f49\u5316\u70ba\u5728\u81e8\u5e8a\u4e0a\u5177\u6709\u5be6\u8cea\u610f\u7fa9\u7684\u9810\u5f8c\u6aa2\u6e2c\uff08prognostic test\uff09\u548c\u5b50\u5bae\u5167\u819c\u5bb9\u53d7\u80fd\u529b\u7684\u6cbb\u7642\uff0c\u5247\u4ecd\u6709\u5f85\u9032\u4e00\u6b65\u7684\u7814\u7a76\u3002<\/p>\n

     <\/strong><\/p>\n

    \u53c3\u8003\u8cc7\u6599\uff1a<\/strong><\/p>\n

      \n
    1. Simon C, Gomez C, Cabanillas S, Vladimirov IK, Castillon G, Giles J, Boynukalin JK, Findikli N, Ortega I, Vidal C, Izquierdo A, Portela S, Frantz N, Taguchi S, Labarta E, Coelho FC, Mackens<\/a> S, Santamaria X, Mu\u00f1oz E, Barrera SG, Fern\u00e1ndez-S\u00e1nchez M, Ferrando M, Pellicer M, Mol BW, Valbuena D. In vitro fertilization with personalized blastocyst transfer versus frozen or fresh blastocyst transfer: a multicenter, randomized clinical trial. Fertility and Sterility, 2019; 112. e56-e57. doi. 10.1016\/j.fertnstert.2019.07.273.<\/li>\n
    2. Dvo\u0159an M, Vodi\u010dka J, Dost\u00e1l J, Hajd\u016fch M, D\u017eub\u00e1k P, Pe\u0161kov\u00e1 M, Pilka R. Implantation and diagnostics of endometrial receptivity.<\/a> Ceska Gynekol. 2018 Fall;83(4):291-298.<\/li>\n
    3. Martins RS, Oliani AH, Oliani DV, de Oliveira JM. Continuous endometrial volumetric analysis for endometrial receptivity assessment on assisted reproductive technology cycles. BMC Pregnancy Childbirth. 2020 Nov 3;20(1):663. doi: 10.1186\/s12884-020-03372-2.<\/li>\n
    4. Craciunas L, Gallos I, Chu J, Bourne T, Quenby S, Brosens JJ, Coomarasamy A. Conventional and modern markers of endometrial receptivity: a systematic review and meta-analysis. Hum Reprod Update. 2019 Mar 1; 25(2):202-223. doi: 10.1093\/humupd\/dmy044.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

      \u6210\u529f\u61f7\u5b55\u9664\u8207\u80da\u80ce\u672c\u8cea\u6709\u5bc6\u5207\u95dc\u4fc2\u5916\uff0c\u5b50\u5bae\u5167\u819c\u72c0\u6cc1\u4ea6\u70ba\u91cd\u8981\u7684\u4e00\u74b0\u3002\u8a66\u7ba1\u5b30\u5152\u7642\u7a0b\u4e2d\u6e96\u5099\u690d\u5165\u80da\u80ce\u524d\uff0c\u9664\u4e86\u5b89\u6392\u8f38\u5375\u7ba1\u651d\u5f71\u3001\u5b50\u5bae\u93e1\u53ca\u81ea\u9ad4\u514d\u75ab\u7be9\u6aa2\u4ee5\u78ba\u8a8d\u8457\u5e8a\u74b0\u5883\u5916\uff0c\u9084\u9700\u8981\u5229\u7528\u5b50\u5bae\u5167\u819c\u5bb9\u53d7\u6027\u6aa2\u6e2c\uff08ERA\uff09\u4ee5\u9078\u64c7\u6700\u4f73\u6642\u9593\u9ede\u4f86\u300c\u7cbe\u6e96\u690d\u5165\u300d\u80da\u80ce\uff0c\u4fc3\u6210\u8a66\u7ba1\u5b30\u5152\u6210\u529f\u7387\u7684\u986f\u8457\u589e\u52a0\u3002\u6211\u5011\u5728\u672c\u6587\u5c07\u4ecb\u7d39\u8a66\u7ba1\u5b30\u5152\u6280\u8853\u7684\u5b50\u5bae\u5167\u819c\u5bb9\u53d7\u6027\u6aa2\u6e2c\uff0c\u5982\u4f55\u85c9\u7531\u627e\u5230\u500b\u4eba\u6700\u9069\u5408\u7684\u8457\u5e8a\u7a97\u671f\uff0c\u4ee5\u5354\u52a9\u53d7\u5230\u4e0d\u5b55\u75c7\u56f0\u64fe\u7684\u592b\u59bb\u63d0\u5347\u6210\u529f\u61f7\u5b55\u7684\u6a5f\u6703\u3002<\/p>\n","protected":false},"author":20,"featured_media":36254,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,1025],"tags":[4841,4845,4844,4846,4842],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2021\/02\/644368.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/36245"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=36245"}],"version-history":[{"count":2,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/36245\/revisions"}],"predecessor-version":[{"id":36255,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/36245\/revisions\/36255"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/36254"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=36245"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=36245"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=36245"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}