{"id":34772,"date":"2019-12-18T00:29:30","date_gmt":"2019-12-17T16:29:30","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=34772"},"modified":"2020-10-23T12:46:57","modified_gmt":"2020-10-23T04:46:57","slug":"%e6%99%ba%e6%85%a7%e5%9e%8b%e7%84%a1%e7%97%9b%e7%9a%84%e7%b6%93%e7%9a%ae%e8%97%a5%e7%89%a9%e9%81%9e%e9%80%81%e7%b3%bb%e7%b5%b1-%e5%be%ae%e9%87%9d%e8%b2%bc%e7%89%87","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=34772","title":{"rendered":"\u667a\u6167\u578b\u7121\u75db\u7684\u7d93\u76ae\u85e5\u7269\u905e\u9001\u7cfb\u7d71\uff0d\u5fae\u91dd\u8cbc\u7247"},"content":{"rendered":"<p><span style=\"color: #333399;\"><strong>\u5fae\u91dd\u8cbc\u7247\uff08microneedle patch, MNP\uff09\u662f\u4e00\u7a2e\u65b0\u7a4e\u6027\u53ca\u9769\u547d\u6027\u7684\u7d93\u76ae\u85e5\u7269\u905e\u9001\u7cfb\u7d71\uff08transdermal drug delivery system, TDDS\uff09\uff0c\u56e0\u8cbc\u7247\u4e0a\u5fae\u91dd\uff08microneedle\uff09\u751a\u77ed\u4e0d\u6703\u89f8\u53ca\u76ae\u4e0b\u795e\u7d93\u7cfb\u7d71\u75db\u89ba\u611f\u53d7\u5668\u800c\u5f15\u767c\u75db\u89ba\uff0c\u9084\u53ef\u5feb\u901f\u800c\u6709\u6548\u7684\u50b3\u905e\u5927\u5206\u5b50\u85e5\u7269\u76f4\u63a5\u8d8a\u904e\u76ae\u819a\u89d2\u8cea\u5c64\u800c\u9032\u5165\u4eba\u9ad4\uff0c\u6545MNP\u517c\u5177\u7d93\u76ae\u5438\u6536\u53ca\u76ae\u4e0b\u6ce8\u5c04\u905e\u9001\u85e5\u7269\u7684\u512a\u9ede\u3002\u672c\u6587\u9664\u4ecb\u7d39\u8b80\u8005\u8a8d\u8b58 MNP\u7684\u7d50\u69cb\u3001\u7279\u6027\u3001\u512a\u9ede\u53ca\u61c9\u7528\u5916\uff0c\u4e26\u63a2\u8a0eMNP\u958b\u767c\u7684\u524d\u666f\u8207\u6311\u6230\u3002<\/strong><\/span><\/p>\n<p><strong><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-34782\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/12\/Figure.jpg\" alt=\"\" width=\"649\" height=\"410\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/12\/Figure.jpg 649w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/12\/Figure-300x190.jpg 300w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/12\/Figure-600x379.jpg 600w\" sizes=\"(max-width: 649px) 100vw, 649px\" \/>\u64b0\u6587\uff5c\u9673\u6df5\u9293<\/strong><\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u4ec0\u9ebc\u662f<\/strong><strong>\u5fae\u91dd\u8cbc\u7247<\/strong><\/span><\/p>\n<p>\u5fae\u91dd\uff08microneedle\uff09\u662f\u4e00\u7a2e\u5fae\u7c73\u5927\u5c0f\u7684\u91dd\u982d\uff08\u9577\uff1a150-1500\u5fae\u7c73\uff0c\u5bec\uff1a50-250\u5fae\u7c73\uff0c\u539a\u5ea6\uff1a1-25\u5fae\u7c73\uff09\uff0c\u53ef\u4f5c\u70ba\u900f\u76ae\u65bd\u7528\u4ee5\u905e\u9001\u85e5\u7269\u6216\u75ab\u82d7\u7684\u5fae\u89c0\u65bd\u7528\u5668\uff0c\u662f\u85c9\u7531\u5c07\u5fae\u89c0\u7d50\u69cb\u8755\u523b\u5230\u6a39\u8102\u6216\u77fd\u800c\u88fd\u6210\uff0c\u7d44\u6210\u6210\u5206\u5305\u62ec\u77fd\u3001\u9226\u3001\u4e0d\u92b9\u92fc\u548c\u805a\u5408\u7269\u7b49\u591a\u7a2e\u6750\u6599\uff0c\u6709\u4e9b\u5fae\u91dd\u5247\u7531\u85e5\u7269\u88fd\u6210\uff0c\u53ef\u4ee5\u8f38\u9001\u5230\u9ad4\u5167\uff0c\u4f46\u88ab\u505a\u6210\u91dd\u72c0\uff0c\u4ee5\u4fbf\u7a7f\u900f\u76ae\u819a\u3002\u5fae\u91dd\u8cbc\u7247\uff08MNP\uff09\u901a\u5e38\u7531\u5e7e\u6839\u5230\u5e7e\u767e\u6839\u5fae\u91dd\u7684\u5c0f\u9663\u5217\uff08array\uff09\u69cb\u6210\uff0c\u5fae\u91dd\u6392\u5217\u5728\u5c0f\u8cbc\u7247\u4e0a\uff0c\u6210\u70ba\u4e00\u7a2e\u76ae\u4e0b\u6ce8\u5c04\u91dd\u982d\uff08hypodermic needle\uff09\u548c\u900f\u76ae\u8cbc\u7247\uff08transdermal patch\uff09\u7684\u6df7\u5408\u88dd\u7f6e\uff0c\u4e26\u900f\u904e\u8cbc\u7247\u6216\u5176\u4ed6\u58d3\u5370\u8a2d\u5099\u5c07\u8a72\u9663\u5217\u65bd\u52a0\u5230\u75c5\u60a3\u7684\u76ae\u819a\u4e0a\u4e00\u6bb5\u6642\u9593\u4ee5\u6709\u6548\u5730\u65bd\u85e5\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u70ba\u4f55\u8981\u4f7f\u7528<\/strong><strong>\u5fae\u91dd\u8cbc\u7247<\/strong><\/span><\/p>\n<p>\u76ae\u819a\u7531\u5916\u800c\u5167\u53ef\u5206\u6210\u89d2\u8cea\u5c64\uff08stratum corneum\uff09\uff0c\u8868\u76ae\uff08epidermis\uff09\u548c\u771f\u76ae\uff08dermis\uff09\u4e09\u5c64\uff0c\u5176\u4e2d\u89d2\u8cea\u5c64\u6700\u5805\u786c\uff0c\u800c\u771f\u76ae\u5c64\u6700\u539a\u3002\u7d93\u76ae\u819a\u9032\u884c\u85e5\u7269\u50b3\u905e\u7684\u4e3b\u8981\u969c\u7919\u662f\u89d2\u8cea\u5c64\uff0c\u56e0\u70ba\u5b83\u50c5\u5141\u8a31\u67d0\u4e9b\u5206\u5b50\uff08\u5982\u89aa\u8102\u6027\u548c\u4f4e\u5206\u5b50\u91cf\u85e5\u7269\uff09\u901a\u904e\u3002\u50b3\u7d71\u4e0a\u6700\u5e38\u7528\u7684\u7d93\u76ae\u85e5\u7269\u905e\u9001\u7cfb\u7d71\uff08TDDS\uff09\u662f\u76ae\u4e0b\u6ce8\u5c04\u91dd\u982d\u3001\u5916\u7528\u85e5\u818f\u53ca\u900f\u76ae\u8cbc\u7247\u3002\u76ae\u4e0b\u6ce8\u5c04\u91dd\u982d\u53ef\u4ee5\u91cb\u653e90-100%\u7684\u8f09\u85e5\u91cf\uff0c\u4f46\u91dd\u982d\u6df1\u5165\u5b58\u5728\u75db\u89ba\u611f\u53d7\u5668\u7684\u771f\u76ae\uff0c\u6703\u5f15\u8d77\u75c5\u60a3\u75bc\u75db\u800c\u61c9\u76e1\u91cf\u907f\u514d\u4f7f\u7528\uff1b\u5916\u7528\u85e5\u818f\u50c5\u5728\u76ae\u819a\u8868\u9762\u5857\u62b9\uff0c\u751f\u9ad4\u53ef\u5229\u7528\u5ea6\uff08bioavailability, BA\uff09\u56e0\u89d2\u8cea\u5c64\u969c\u58c1\u800c\u8f03\u4f4e\uff1b\u900f\u76ae\u8cbc\u7247\u8cbc\u65bc\u76ae\u819a\u8868\u9762\uff0c\u85e5\u7269\u4ea6\u9808\u901a\u904e\u89d2\u8cea\u5c64\u5c4f\u969c\uff0c\u6545BA\u4e5f\u8f03\u4f4e\uff0c\u6dfb\u52a0\u6ef2\u900f\u4fc3\u9032\u5291\u96d6\u53ef\u6539\u5584\u85e5\u7269\u7684\u6ef2\u900f\u6027\uff0c\u4f46\u6210\u6548\u4ecd\u6709\u9650\uff0c\u4e09\u8005\u5747\u6709\u85e5\u7269\u50b3\u905e\u4e0a\u7684\u7f3a\u9ede\u3002\u56e0\u6b64\uff0c\u7814\u7a76\u4eba\u54e1\u81f4\u529b\u65bc\u958b\u767c\u5404\u7a2eTDDS\uff0c\u4ee5\u6539\u5584\u85e5\u7269\u901a\u904e\u76ae\u819a\u7684\u6ef2\u900f\u6027\u53caBA\uff0c\u5982\u8ca0\u8f09\u5948\u7c73\u8f09\u9ad4\uff08nanocarrier\uff09\u7684\u5c40\u90e8\u5916\u7528\u85e5\u818f\u3001\u6539\u826f\u578b\u900f\u76ae\u8cbc\u7247\u53caMNP\u3002MNP\u53ef\u4f7f\u89aa\u6c34\u6027\u9ad8\u5206\u5b50\u91cf\u5316\u5408\u7269\u8d8a\u904e\u89d2\u8cea\u5c64\uff0c\u7121\u75db\u5730\u5c07100%\u8f09\u85e5\u91cf\u76f4\u63a5\u905e\u9001\u5230\u8868\u76ae\u6216\u771f\u76ae\u5c64\u800c\u9032\u5165\u9ad4\u5167\uff0c\u514b\u670d\u4f7f\u7528\u5916\u7528\u85e5\u818f\u6216\u900f\u76ae\u8cbc\u7247\u6642\uff0c\u8a31\u591a\u85e5\u7269\u7121\u6cd5\u4ee5\u6cbb\u7642\u6240\u9700\u7684\u901f\u7387\u7a7f\u904e\u76ae\u819a\u7684\u7f3a\u9ede\uff0c\u4e26\u517c\u5177\u5176\u4ed6TDDS\u7684\u512a\u9ede\uff08\u88681\uff09\u3002<\/p>\n<p style=\"text-align: center;\">\u88681. \u5404\u7a2e\u7d93\u76ae\u85e5\u7269\u905e\u9001\u7cfb\u7d71\u7684\u6bd4\u8f03<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-34776\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/12\/tab.png\" alt=\"\" width=\"670\" height=\"604\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/12\/tab.png 670w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/12\/tab-300x270.png 300w\" sizes=\"(max-width: 670px) 100vw, 670px\" \/><\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u524d\u666f\u8207\u6311\u6230<\/strong><\/span><\/p>\n<p>\u958b\u767cMNP\u7684\u4e3b\u8981\u76ee\u7684\u662f\u901a\u904e\u76ae\u4e0b\u6ce8\u5c04\u5275\u9020\u51fa\u5fae\u7c73\u5c3a\u5bf8\u7684\u50b3\u8f38\u8def\u5f91\uff0c\u7834\u58de\u89d2\u8cea\u5c64\u4ee5\u5141\u8a31\u5927\u5206\u5b50\u901a\u904e\u800c\u589e\u52a0\u6ef2\u900f\u6027\u53caBA\u3002MNP\u9664\u4e86\u53ef\u4ee5\u589e\u52a0\u85e5\u6548\u4e26\u6539\u5584\u7642\u6548\u5916\uff0c\u9084\u53ef\u4ee5\u63d0\u4f9b\u9ad8\u6e96\u78ba\u5ea6\u53ca\u9ad8\u518d\u73fe\u6027\u7684\u7d50\u679c\uff0c\u4e26\u5728\u81e8\u5e8a\u8a66\u9a57\u7684\u53d7\u8a66\u8005\u9593\u5448\u73fe\u7684BA\u5dee\u7570\u6700\u5c0f\u3002\u73fe\u4eca\u6700\u5177\u6f5b\u529b\u7684\u767c\u5c55\u5728\u65bc\u958b\u767c\u53ef\u905e\u9001\u75ab\u82d7\u7684MNP\uff0c\u4e3b\u8981\u7684\u512a\u52e2\u6709\u4e8c\uff1a\u7b2c\u4e00\uff0c\u7576\u50b3\u67d3\u75c5\u75ab\u60c5\u7a81\u7136\u7206\u767c\u6642\uff0c\u6c11\u773e\u7121\u9808\u91ab\u7642\u4eba\u54e1\u5354\u52a9\u6253\u91dd\uff0c\u53ef\u7d93\u90f5\u5bc4\u65b9\u5f0f\uff0c\u5c07\u75ab\u82d7MNP\u5bc4\u7d66\u4e00\u822c\u5927\u773e\u81ea\u884c\u63a5\u7a2e\uff0c\u4ee5\u6e1b\u5c11\u4ea4\u53c9\u611f\u67d3\u7684\u6a5f\u6703\uff0c\u907f\u514d\u6d41\u884c\u7bc4\u570d\u64f4\u5927\uff1b\u7b2c\u4e8c\uff0c\u7d93\u52d5\u7269\u5be6\u9a57\u8b49\u660e\uff0c\u7576\u75ab\u82d7MNP\u8cbc\u4e0a\u5f8c\uff0c\u6703\u523a\u6fc0\u76ae\u819a\u771f\u76ae\u5c64\u4e4b\u514d\u75ab\u7d30\u80de\u7acb\u5373\u7522\u751f\u514d\u75ab\u53cd\u61c9\uff0c\u53ef\u4ee5\u6700\u5c11\u7684\u75ab\u82d7\u4f7f\u7528\u91cf\uff0c\u5feb\u901f\u7522\u751f\u9810\u9632\u53ca\u4fdd\u8b77\u7684\u6548\u679c\uff0c\u5176\u4ed6\u512a\u52e2\u9084\u5305\u62ec\u7121\u75db\u3001\u7121\u91dd\u50b7\u3001\u5fae\u751f\u7269\u5165\u4fb5\u7387\u4f4e\u3001\u6709\u5bb3\u5ee2\u68c4\u7269\u5c11\u53ca\u5132\u5b58\u3001\u904b\u8f38\u7121\u9700\u51b7\u93c8\uff08cold chain\uff09\u7b49\u3002<\/p>\n<p>\u5118\u7ba1MNP\u6709\u5f88\u591a\u512a\u9ede\uff0c\u524d\u666f\u5341\u5206\u770b\u597d\uff0c\u4f46\u4ecd\u6709\u4e00\u4e9b\u6311\u6230\u5b58\u5728\uff0c\u4f8b\u5982\uff1a\u53ef\u80fd\u5c0d\u76ae\u819a\u9020\u6210\u523a\u6fc0\u6216\u904e\u654f\uff1b\u91dd\u982d\u7684\u5c3a\u5bf8\u5f88\u5c0f\u4e14\u5f88\u7d30\uff0c\u5fae\u91dd\u53ef\u80fd\u6298\u65b7\uff0c\u5982\u679c\u4fdd\u7559\u5728\u76ae\u819a\u5167\uff0c\u53ef\u80fd\u6703\u5f15\u8d77\u554f\u984c\u3002\u7136\u800c\uff0c\u9019\u4e9b\u98a8\u96aa\u767c\u751f\u7387\u975e\u5e38\u4f4e\uff0c\u53ef\u4ee5\u900f\u904e\u9078\u64c7\u8f03\u4f73\u7684\u5fae\u91dd\u88fd\u4f5c\u6750\u6599\u4f86\u514b\u670d\u3002\u76ee\u524d\u5728MNP\u7684\u81e8\u5e8a\u524d\u7814\u7a76\u96d6\u5df2\u53d6\u5f97\u76f8\u7576\u9032\u5c55\uff0c\u4f46\u8981\u5728\u81e8\u5e8a\u4e0a\u61c9\u7528\u4ecd\u9700\u9032\u4e00\u6b65\u7684\u6e2c\u8a66\uff0c\u7279\u5225\u662f\u5728\u50b3\u905e\u75ab\u82d7\u7684MNP\u958b\u767c\u4e0a\uff0c\u61c9\u7576\u5728\u75ab\u82d7\u5b78\uff0c\u514d\u75ab\u5b78\u548c\u6750\u6599\u79d1\u5b78\u7b49\u591a\u500b\u9818\u57df\u4e2d\u9032\u884c\u66f4\u6df1\u5165\u7684\u7814\u7a76\u3002\u6b64\u5916\uff0c\u5728\u898f\u6a21\u5316\u751f\u7522\u3001\u6cd5\u898f\u6838\u51c6\u53ca\u5e02\u5834\u7d93\u71df\u884c\u92b7\u65b9\u9762\u4ea6\u61c9\u52a0\u901f\u3002\u7531\u65bcMNP\u5728\u6709\u6548\u6027\u3001\u6548\u7387\u3001\u5b89\u5168\u6027\u548c\u75c5\u60a3\u4f9d\u5f9e\u6027\u5177\u6709\u591a\u91cd\u512a\u52e2\uff0c\u53ef\u671b\u5728\u4e0d\u4e45\u7684\u5c07\u4f86\u5ee3\u6cdb\u61c9\u7528\u65bc\u81e8\u5e8a\u6cbb\u7642\u548c\u75ab\u82d7\u63a5\u7a2e\u3002<\/p>\n<p><strong>&nbsp;<\/strong><\/p>\n<p><strong>\u53c3\u8003\u8cc7\u6599\uff1a<\/strong><\/p>\n<ol>\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Waghule%20T%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30551375\">Waghule T<\/a>, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Singhvi%20G%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30551375\">Singhvi G<\/a>, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Dubey%20SK%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30551375\">Dubey SK<\/a>, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Pandey%20MM%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30551375\">Pandey MM<\/a>, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Gupta%20G%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30551375\">Gupta G<\/a>, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Singh%20M%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30551375\">Singh M<\/a>, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Dua%20K%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30551375\">Dua K<\/a>. Microneedles: A smart approach and increasing potential for transdermal drug delivery system. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Microneedles%3A+A+smart+approach+and+increasing+potential+for+transdermal+drug+delivery+system\">Biomed Pharmacother.<\/a> 2019 Jan;109:1249-1258. doi: 10.1016\/j.biopha.2018.10.078. Epub 2018 Nov 9.<\/li>\n<li>\u5289\u5927\u4f7c\uff0c\u8449\u4fee\u92d2\u3002<a href=\"http:\/\/scitechreports.blogspot.com\/2019\/03\/blog-post_46.html\">\u7121\u75db\u905e\u85e5\u65b0\u9769\u547d\uff0d\u5fae\u91dd\u8cbc\u7247\u7684\u9032\u5316\u53f2<\/a>\uff0c\u79d1\u6280\u5831\u5c0e\/\u79d1\u5b78\u6708\u520a\uff0c2019\u5e743\u67081\u65e5\uff0c447\u671f\uff0c4-8\u3002<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>\u5fae\u91dd\u8cbc\u7247\uff08microneedle patch, MNP\uff09\u662f\u4e00\u7a2e\u65b0\u7a4e\u6027\u53ca\u9769\u547d\u6027\u7684\u7d93\u76ae\u85e5\u7269\u905e\u9001\u7cfb\u7d71\uff08transdermal drug delivery system, TDDS\uff09\uff0c\u56e0\u8cbc\u7247\u4e0a\u5fae\u91dd\uff08microneedle\uff09\u751a\u77ed\u4e0d\u6703\u89f8\u53ca\u76ae\u4e0b\u795e\u7d93\u7cfb\u7d71\u75db\u89ba\u611f\u53d7\u5668\u800c\u5f15\u767c\u75db\u89ba\uff0c\u9084\u53ef\u5feb\u901f\u800c\u6709\u6548\u7684\u50b3\u905e\u5927\u5206\u5b50\u85e5\u7269\u76f4\u63a5\u8d8a\u904e\u76ae\u819a\u89d2\u8cea\u5c64\u800c\u9032\u5165\u4eba\u9ad4\uff0c\u6545MNP\u517c\u5177\u7d93\u76ae\u5438\u6536\u53ca\u76ae\u4e0b\u6ce8\u5c04\u905e\u9001\u85e5\u7269\u7684\u512a\u9ede\u3002\u672c\u6587\u9664\u4ecb\u7d39\u8b80\u8005\u8a8d\u8b58 MNP\u7684\u7d50\u69cb\u3001\u7279\u6027\u3001\u512a\u9ede\u53ca\u61c9\u7528\u5916\uff0c\u4e26\u63a2\u8a0eMNP\u958b\u767c\u7684\u524d\u666f\u8207\u6311\u6230\u3002<\/p>\n","protected":false},"author":20,"featured_media":34782,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,1025],"tags":[4486,4485],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/12\/Figure.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/34772"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=34772"}],"version-history":[{"count":8,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/34772\/revisions"}],"predecessor-version":[{"id":34796,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/34772\/revisions\/34796"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/34782"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=34772"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=34772"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=34772"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}