{"id":34148,"date":"2019-06-14T00:46:40","date_gmt":"2019-06-13T16:46:40","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=34148"},"modified":"2019-06-12T09:55:54","modified_gmt":"2019-06-12T01:55:54","slug":"%e5%97%85%e9%9e%98%e7%b4%b0%e8%83%9e%e5%b0%87%e6%88%90%e7%82%ba%e6%b2%bb%e7%99%82%e8%85%a6%e7%99%8c%e6%96%b0%e5%88%a9%e5%99%a8","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=34148","title":{"rendered":"\u55c5\u9798\u7d30\u80de\u5c07\u6210\u70ba\u6cbb\u7642\u8166\u764c\u65b0\u5229\u5668"},"content":{"rendered":"<p><span style=\"color: #333399;\"><strong>\u7814\u7a76\u767c\u73fe\uff0c\u5c0d\u55c5\u795e\u7d93\u518d\u751f\u80fd\u529b\u81f3\u95dc\u91cd\u8981\u7684\u4e00\u7a2e\u7279\u6b8a\u7d30\u80de\u53ef\u4ee5\u642d\u914d\u57fa\u56e0\u8f49\u6b96\u4f86\u6cbb\u7642\u8166\u764c\u3002<\/strong><\/span><\/p>\n<figure id=\"attachment_34151\" aria-describedby=\"caption-attachment-34151\" style=\"width: 450px\" class=\"wp-caption alignleft\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-34151\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/06\/mental-health-3337026_640.jpg\" alt=\"\" width=\"450\" height=\"321\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/06\/mental-health-3337026_640.jpg 640w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/06\/mental-health-3337026_640-300x214.jpg 300w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><figcaption id=\"caption-attachment-34151\" class=\"wp-caption-text\">@pixaby.com<\/figcaption><\/figure>\n<p><strong>\u64b0\u6587\uff5c\u9673\u6566\u7406<\/strong><\/p>\n<p>\u8166\u7624\u662f\u8166\u7d30\u80de\u4e0d\u6b63\u5e38\u5206\u88c2\u589e\u6b96\uff0c\u4e00\u65e6\u816b\u7624\u9577\u5927\u58d3\u8feb\u8166\u90e8\u5c31\u6703\u5c0d\u4eba\u9ad4\u7522\u751f\u56b4\u91cd\u5f71\u97ff\u3002\u7f79\u60a3\u8166\u7624\u7684\u539f\u56e0\u5230\u76ee\u524d\u70ba\u6b64\u4ecd\u4e0d\u751a\u6e05\u695a\u3002\u8166\u7624\u66f4\u662f\u7f79\u764c\u5152\u7ae5\u4e2d\u767c\u751f\u7387\u7b2c\u4e8c\u9ad8\uff0c\u50c5\u6b21\u65bc\u8840\u764c\u3002\u795e\u7d93\u81a0\u8cea\u6bcd\u7d30\u80de\u7624\uff08glioblastoma\uff09\u662f\u5e38\u898b\u53c8\u81f4\u547d\u7684\u8166\u764c\uff0c\u767c\u751f\u7387\u7d04\u70ba\u5341\u842c\u5206\u4e4b\u4e09\uff0c\u7136\u800c\u78ba\u8a3a\u5f8c\u75c5\u60a3\u53ea\u5269\u4e00\u5e74\u591a\u7684\u58fd\u547d\uff0c\u5373\u4f7f\u5408\u4f75\u5316\u7642\u6216\u96fb\u7642\uff0c\u53ef\u4ee5\u5b58\u6d3b\u8d85\u904e\u4e94\u5e74\u7684\u75c5\u60a3\u53ea\u6709\u4e0d\u5230\u767e\u5206\u4e4b\u4e94\u3002\u8166\u764c\u6b7b\u4ea1\u4e3b\u8981\u539f\u56e0\u5982\u521d\u671f\u75c7\u72c0\u4e0d\u660e\u986f\u800c\u5ef6\u8aa4\u6cbb\u7642\u6642\u9593\u3001\u816b\u7624\u8207\u6b63\u5e38\u8166\u7d44\u7e54\u908a\u754c\u6a21\u7cca\uff0c\u4ee5\u624b\u8853\u5207\u9664\u6642\u70ba\u4e86\u4fdd\u8b77\u8166\u7684\u91cd\u8981\u90e8\u4f4d\uff0c\u7121\u6cd5\u5c07\u6709\u7591\u616e\u7684\u7d44\u7e54\u5fb9\u5e95\u5207\u9664\uff0c\u975e\u5e38\u5bb9\u6613\u5fa9\u767c\u3002\u81e8\u5e8a\u4e0a\u6cbb\u7642\u5176\u4ed6\u764c\u75c7\u7684\u5316\u7642\u85e5\u7269\u62ff\u4f86\u6cbb\u7642\u8166\u764c\u5e7e\u4e4e\u90fd\u5931\u6548\uff0c\u539f\u56e0\u662f\u70ba\u4e86\u7dad\u6301\u8166\u90e8\u751f\u7406\u74b0\u5883\u7684\u7a69\u5b9a\uff0c\u8166\u7d30\u80de\u548c\u5fae\u8840\u7ba1\u9593\u6709\u7279\u6b8a\u7684\u7d44\u6210\uff0c\u4f7f\u5f97\u5316\u7642\u85e5\u7269\u88ab\u963b\u64cb\u5728\u5916\u7121\u6cd5\u9032\u5165\u816b\u7624\u4f4d\u7f6e\u4f86\u6cbb\u7642\u3002\u5c11\u6578\u53ef\u7528\u7684\u5316\u7642\u85e5\u7269\u537b\u6709\u8fd1\u4e03\u6210\u75c5\u60a3\u764c\u7d30\u80de\u6703\u7522\u751f\u6297\u85e5\u6027\u3002\u5982\u4f55\u4f7f\u85e5\u7269\u8207\u6cbb\u7642\u5f9e\u5fae\u8840\u7ba1\u8d8a\u904e\u8166\u7d30\u80de\u4f48\u4e0b\u7684\u9285\u7246\u9435\u58c1\uff0c\u662f\u8166\u764c\u6cbb\u7642\u7814\u7a76\u7684\u4e3b\u8981\u65b9\u5411\u3002\u6b63\u5982\u81fa\u7063\u4e2d\u592e\u7814\u7a76\u9662\u7814\u7a76\u5718\u968a\u4eca\u5e74\u4e5f\u767c\u73fe\uff0c\u6ce8\u5c04\u6975\u4f4e\u5291\u91cf\u7684\u8840\u7ba1\u751f\u9577\u56e0\u5b50\uff0c\u80fd\u5920\u4f7f\u5316\u7642\u85e5\u7269\u9806\u5229\u901a\u904e\u5fae\u8840\u7ba1\u8207\u8166\u7d30\u80de\u9032\u5165\u8166\u7624\u90e8\u4f4d\u3002<\/p>\n<p>\u7f8e\u570b\u9ebb\u7701\u7e3d\u91ab\u9662( Massachusetts General Hospital ) \u7814\u7a76\u767c\u73fe\u5229\u7528\u55c5\u9798\u7d30\u80de( olfactory ensheathing cells) \u4f86\u6d88\u6ec5\u764c\u7d30\u80de\u7684\u6a19\u9776\u6cbb\u7642\u65b0\u65b9\u6cd5\uff0c\u4e14\u6210\u529f\u8b93\u816b\u7624\u7e2e\u5c0f\u3001\u5be6\u9a57\u52d5\u7269\u5b58\u6d3b\u66f4\u4e45\u3002\u9f3b\u8154\u4e2d\u55c5\u795e\u7d93\u5143\u7684\u529f\u80fd\u662f\u6355\u6293\u6c23\u5473\u5206\u5b50\u4e26\u50b3\u9001\u8a0a\u606f\u5230\u5927\u8166\u3002\u54fa\u4e73\u52d5\u7269\u7684\u55c5\u795e\u7d93\u5143\u7d42\u5176\u4e00\u751f\u90fd\u53ef\u4ee5\u5728\u53d7\u5230\u640d\u50b7\u6216\u662f\u6b63\u5e38\u6b7b\u4ea1\u6642\u518d\u751f\uff0c\u9019\u5728\u795e\u7d93\u7cfb\u7d71\u76f8\u7576\u5c11\u898b\uff0c\u795e\u7d93\u7e96\u7dad\u5f9e\u9f3b\u8154\u5ef6\u4f38\u9032\u5165\u5927\u8166\u55c5\u7403 (olfactory bulb\uff09\u3002\u55c5\u9798\u7d30\u80de\u662f\u795e\u7d93\u7cfb\u7d71\u5167\u7684\u652f\u6301\u7d30\u80de, \u7dad\u6301\u795e\u7d93\u5143\u7d50\u69cb\u548c\u6b63\u5e38\u529f\u80fd\u3002\u55c5\u9798\u7d30\u80de\u4e0d\u6703\u5728\u55c5\u795e\u7d93\u8ef8\u7a81\u4e0a\u5f62\u6210\u9ad3\u9798\uff0c\u800c\u662f\u4ee5\u5176\u7a81\u8d77\u53bb\u570d\u7e5e\u8a31\u591a\u81e8\u8fd1\u7684\u795e\u7d93\u8ef8\u7a81\u3002\u7814\u7a76\u767c\u73fe\u55c5\u795e\u7d93\u7e96\u7dad\u518d\u751f\u7b49\u7279\u6027\uff0c\u5927\u90e8\u5206\u8981\u6b78\u529f\u65bc\u55c5\u9798\u7d30\u80de\uff0c\u800c\u79fb\u690d\u55c5\u9798\u7d30\u80de\u5230\u810a\u9ad3\u640d\u50b7\u8655\u6709\u4fee\u5fa9\u7684\u6548\u679c\u3002<\/p>\n<p>\u7814\u7a76\u5718\u968a\u5728\u5c0b\u627e\u53ef\u505a\u7d30\u80de\u79fb\u690d\u6cbb\u7642\u8166\u764c\u7684\u904e\u7a0b\u4e2d\uff0c\u55c5\u9798\u7d30\u80de\u5929\u751f\u5c31\u53ef\u4ee5\u81ea\u7531\u9032\u5165\u5927\u8166\u53c8\u6703\u5c0d\u816b\u7624\u6240\u5206\u6ccc\u767c\u708e\u7269\u8cea\u7dca\u8ffd\u4e0d\u6368\u7684\u7279\u6027\u8b93\u4ed6\u5011\u773c\u775b\u70ba\u4e4b\u4e00\u4eae\uff0c\u767c\u73fe\u55c5\u9798\u7d30\u80de\u53ef\u80fd\u6210\u70ba\u8166\u764c\u6cbb\u7642\u7684\u7d55\u4f73\u9078\u9805\uff0c\u56e0\u6b64\u60f3\u76e1\u8fa6\u6cd5\u8981\u63a2\u7d22\u55c5\u9798\u7d30\u80de\u6cbb\u7642\u8166\u764c\u7684\u6f5b\u529b\u3002\u4ed6\u5011\u900f\u904e\u57fa\u56e0\u8f49\u6b96\u6280\u8853\u8b93\u55c5\u9798\u7d30\u80de\u80fd\u88fd\u9020\u5408\u6210\u86cb\u767d CU\uff0cCU\u5408\u6210\u86cb\u767d\u7684\u529f\u80fd\u662f\u8b93\u7121\u6bd2\u524d\u9a45\u85e5\u7269 5-FC \u8f49\u8b8a\u6210\u53ef\u6bba\u6b7b\u764c\u7d30\u80de\u7684\u5316\u7642\u85e5 5-FU\u3002\u7814\u7a76\u5718\u968a\u5148\u5728\u7d30\u80de\u57f9\u990a\u4e2d\uff0c\u78ba\u8a8d\u88fd\u9020CU\u86cb\u767d\u7684\u55c5\u9798\u7d30\u80de\u53ef\u4ee5\u5c07 5-FC \u8f49\u8b8a\u6210 5-FU\uff0c\u4e14\u9020\u6210\u764c\u7d30\u80de\u6b7b\u4ea1\u3002\u63a5\u8457\u4ed6\u5011\u9032\u4e00\u6b65\u5c07\u4eba\u9ad4\u8166\u764c\u7d30\u80de\u548c\u5c0f\u9f20\u55c5\u9798\u7d30\u80de\u5148\u5f8c\u6ce8\u5165\u5c0f\u9f20\u9f3b\u8154\uff0c\u767c\u73fe\u55c5\u9798\u7d30\u80de\u4e0d\u53ea\u6703\u79fb\u52d5\u5230\u816b\u7624\u7d30\u80de\u7684\u4f4d\u7f6e\uff0c\u9084\u6703\u8ddf\u8457\u8f49\u79fb\u5230\u5468\u570d\u8166\u90e8\u7684\u816b\u7624\u7d30\u80de\u4e00\u8d77\u79fb\u52d5\u3002\u5be6\u9a57\u4e2d\u7814\u7a76\u5718\u968a\u7b2c\u4e00\u9031\u5c07\u8166\u764c\u7d30\u80de\u6ce8\u5165\u5c0f\u9f20\u5927\u8166\uff0c\u7b2c\u4e8c\u9031\u5206\u5225\u5c07\u80fd\u88fd\u9020CU\u86cb\u767d\u7684\u55c5\u9798\u7d30\u80de\u548c\u5c0d\u7167\u7d44\u6ce8\u5165\u5c0f\u9f20\u9f3b\u8154\uff0c\u7b2c\u4e09\u9031\u4e0d\u505a\u8655\u7406\u8b93\u7d30\u80de\u751f\u9577\uff0c\u7b2c\u56db\u9031\u958b\u59cb\u6bcf\u5929\u70ba\u5c0f\u9f20\u6ce8\u5c045-FC\u3002\u5230\u7b2c\u4e03\u9031\u767c\u73fe\u6ce8\u5c04\u80fd\u88fd\u9020CU\u86cb\u767d\u55c5\u9798\u7d30\u80de\u7684\u5c0f\u9f20\u8eab\u4e0a\u6bd4\u8d77\u5c0d\u7167\u7d44\u816b\u7624\u986f\u8457\u8f03\u5c0f\u3001\u764c\u7d30\u80de\u8f49\u79fb\u6578\u91cf\u8f03\u5c11\u3001\u764c\u7d30\u80de\u6b7b\u4ea1\u6578\u91cf\u8f03\u591a\u3002\u4ee5\u57fa\u56e0\u8f49\u6b96\u7684\u55c5\u9798\u7d30\u80de\u4f86\u6cbb\u7642\u8166\u764c\u986f\u7136\u76f8\u7576\u6210\u529f\u3002<\/p>\n<p>\u4eba\u9ad4\u795e\u7d93\u7cfb\u7d71\u7684\u5967\u5999\u8655\u6b63\u5728\u65bc\u5176\u7d50\u69cb\u529f\u80fd\u7cbe\u5de7\u8907\u96dc\uff0c\u74b0\u74b0\u76f8\u6263\u7dca\u5bc6\u9023\u7d50\u3002\u800c\u9019\u4e5f\u4f7f\u5f97\u795e\u7d93\u79d1\u5b78\u7814\u7a76\u4e43\u81f3\u75be\u75c5\u6cbb\u7642\u56f0\u96e3\u91cd\u91cd\u3002\u8166\u7624\u6cbb\u7642\u6b63\u56e0\u70ba\u5982\u6b64\uff0c\u9577\u4e45\u4ee5\u4f86\u96e3\u6709\u66f4\u6709\u6548\u5b89\u5168\u7684\u7642\u6cd5\u3002\u79fb\u690d\u55c5\u9798\u7d30\u80de\u6cbb\u7642\u8166\u764c\u5229\u7528\u55c5\u795e\u7d93\u5143\u767c\u80b2\u8207\u81ea\u6211\u4fee\u5fa9\u518d\u751f\u904e\u7a0b\u7684\u7279\u6027\uff0c\u6210\u529f\u7a7f\u8d8a\u5fae\u8840\u7ba1\u9032\u5165\u8166\u7d30\u80de\uff0c\u70ba\u8166\u7624\u6cbb\u7642\u7814\u7a76\u6253\u958b\u4e00\u6247\u7a97\uff0c\u671f\u5f85\u4e0d\u4e45\u7684\u5c07\u4f86\u6709\u66f4\u591a\u7a81\u7834\u548c\u767c\u73fe\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u53c3\u8003\u8cc7\u6599\uff1a<\/strong><\/p>\n<ol>\n<li><a href=\"https:\/\/academic.oup.com\/jnci\/article-abstract\/111\/3\/283\/5106762?redirectedFrom=fulltext\">Olfactory Ensheathing Cells: A Trojan Horse for Glioma Gene Therapy<\/a><\/li>\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1571239\/\">Olfactory ensheathing cells (OECs) and the treatment of CNS injury: advantages and possible caveats.<\/a><\/li>\n<li>\u8166\u7624(brain tumors)\u6cbb\u7642\u6e96\u5247 \u2013 \u81fa\u5317\u69ae\u6c11\u7e3d\u91ab\u9662https:\/\/wd.vghtpe.gov.tw\/hemaonco\/files\/Guide_BrainCA.pdf<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7f8e\u570b\u9ebb\u7701\u7e3d\u91ab\u9662( Massachusetts General Hospital ) \u7814\u7a76\u767c\u73fe\u5229\u7528\u55c5\u9798\u7d30\u80de( olfactory ensheathing cells) \u4f86\u6d88\u6ec5\u764c\u7d30\u80de\u7684\u6a19\u9776\u6cbb\u7642\u65b0\u65b9\u6cd5\uff0c\u4e14\u6210\u529f\u8b93\u816b\u7624\u7e2e\u5c0f\u3001\u5be6\u9a57\u52d5\u7269\u5b58\u6d3b\u66f4\u4e45\u3002<\/p>\n","protected":false},"author":20,"featured_media":34151,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[257,3293,1025],"tags":[278,4287,4288],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2019\/06\/mental-health-3337026_640.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/34148"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=34148"}],"version-history":[{"count":4,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/34148\/revisions"}],"predecessor-version":[{"id":34155,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/34148\/revisions\/34155"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/34151"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=34148"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=34148"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=34148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}