{"id":33877,"date":"2019-04-15T00:40:44","date_gmt":"2019-04-14T16:40:44","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=33877"},"modified":"2022-10-11T13:16:32","modified_gmt":"2022-10-11T05:16:32","slug":"%e5%90%91%e6%98%86%e8%9f%b2%e5%8f%96%e8%97%a5%ef%bc%9a%e5%be%9e%e8%9e%9e%e8%9f%bb%e8%ba%ab%e4%b8%8a%e7%9a%84%e5%be%ae%e7%94%9f%e7%89%a9%e6%89%be%e5%88%b0%e6%96%b0%e5%9e%8b%e6%8a%97%e7%94%9f%e7%b4%a0","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=33877","title":{"rendered":"\u5411\u6606\u87f2\u53d6\u85e5\uff1a\u5f9e\u879e\u87fb\u8eab\u4e0a\u7684\u5fae\u751f\u7269\u627e\u5230\u65b0\u578b\u6297\u751f\u7d20"},"content":{"rendered":"
\"\"
\u5c08\u5011\u990a\u6b96\u771f\u83cc\u7dad\u751f\u7684\u879e\u87fbCyphomyrmex sp. \u5716\u7247\u4f86\u6e90 by ALEX WILD<\/figcaption><\/figure>\n

\u64b0\u6587\uff5c\u9ec3\u4f73\u6b23<\/strong><\/p>\n

 <\/strong>\u6297\u751f\u7d20\u7684\u767c\u73fe\u662f\u91ab\u5b78\u53f2\u4e0a\u91cd\u5927\u7684\u91cc\u7a0b\u7891\uff0c\u8a31\u591a\u56b4\u91cd\u5371\u5bb3\u4eba\u985e\u7684\u7d30\u83cc\u611f\u67d3\u75be\u75c5\u80fd\u88ab\u6709\u6548\u5730\u63a7\u5236\u3002\u4f46\u662f\uff0c\u7531\u65bc\u904e\u5ea6\u6feb\u7528\u6297\u751f\u7d20\uff0c\u4eba\u985e\u4e16\u754c\u6b63\u9762\u81e8\u6297\u751f\u7d20\u8010\u85e5\u6027\u7684\u91cd\u5927\u5371\u6a5f\uff0c\u8a31\u591a\u66fe\u7d93\u662f\u842c\u9748\u4e39\u7684\u6297\u751f\u7d20\u5c0d\u65bc\u67d0\u4e9b\u6709\u8010\u85e5\u6027\u7684\u300c\u8d85\u7d1a\u7d30\u83cc\u300d\u5df2\u7d93\u5931\u53bb\u6548\u7528\u3002\u56e0\u6b64\uff0c\u79d1\u5b78\u5bb6\u6b63\u52aa\u529b\u5c0b\u627e\u65b0\u7684\u65b9\u5f0f\u6216\u85e5\u7269\u4f86\u5c0d\u6297\u9019\u4e9b\u9811\u5f37\u7684\u8d85\u7d1a\u7d30\u83cc\u3002<\/p>\n

\u5176\u4e2d\u4e00\u7a2e\u65b9\u5f0f\u662f\u7814\u7a76\u5176\u4ed6\u7269\u7a2e\u5982\u4f55\u5c0d\u6297\u75c5\u83cc\u7684\u65b9\u6cd5\u3002\u4f8b\u5982\uff0c\u8d85\u904e12,000\u7a2e\u879e\u87fb\u8ddf\u4eba\u985e\u4e00\u6a23\u90fd\u904e\u8457\u5bc6\u96c6\u7684\u7fa4\u9ad4\u751f\u6d3b\uff0c\u751a\u81f3\u9ad8\u9054\u5343\u842c\u7684\u500b\u9ad4\u5728\u540c\u4e00\u500b\u5de2\u7a74\u4e2d\u5171\u5c45\uff0c\u9019\u6a23\u9ad8\u5ea6\u793e\u6703\u5316\u7684\u751f\u6d3b\u65b9\u5f0f\u5fc5\u7136\u6703\u589e\u52a0\u879e\u87fb\u5011\u63a5\u89f8\u75c5\u83cc\u7684\u6a5f\u6703\u3002<\/p>\n

\u5de5\u87fb\u6bcf\u5929\u90fd\u6703\u8f9b\u52e4\u5730\u51fa\u5916\u63a1\u96c6\uff0c\u5e36\u56de\u4f86\u7684\u98df\u7269\u4e2d\u9664\u4e86\u7121\u5bb3\u7684\u5fae\u751f\u7269\uff0c\u4e5f\u540c\u6642\u6703\u9644\u8457\u81f4\u75c5\u7684\u75c5\u83cc\u3002\u518d\u52a0\u4e0a\u6f6e\u6fd5\u6696\u548c\u7684\u87fb\u5de2\u5c0d\u65bc\u9019\u4e9b\u75c5\u83cc\u662f\u7d55\u4f73\u7684\u751f\u9577\u74b0\u5883\u3002\u50c5\u7ba1\u879e\u87fb\u906d\u9047\u75c5\u83cc\u7684\u98a8\u96aa\u975e\u5e38\u9ad8\uff0c\u8a31\u591a\u879e\u87fb\u90fd\u662f\u81ea\u7136\u74b0\u5883\u4e2d\u7684\u512a\u52e2\u7269\u7a2e\uff0c\u7d93\u904e\u9577\u671f\u7684\u6f14\u5316\u904e\u7a0b\uff0c\u4ed6\u5011\u52e2\u5fc5\u767c\u5c55\u51fa\u6709\u6548\u7684\u5c0d\u6297\u6a5f\u5236\u8207\u7b56\u7565\u3002<\/p>\n

\u904e\u53bb\u7684\u6587\u737b\u66fe\u5831\u5c0e\u879e\u87fb\u6703\u5206\u6ccc\u6297\u83cc\u7269\u8cea\u4f86\u6291\u5236\u75c5\u83cc\u7684\u751f\u9577\uff0c\u6700\u8fd1\u4e00\u9805\u8f03\u5927\u898f\u6a21\u7684\u8a66\u9a57\u8b49\u5be6\u4e86\u9019\u500b\u5047\u8aaa\uff0c\u7f8e\u570b\u4e9e\u5229\u6851\u90a3\u5dde\u7acb\u5927\u5b78\u7684\u7814\u7a76\u4eba\u54e1\u63a1\u96c6\u4e86\u7f8e\u570b\u5883\u516720\u500b\u879e\u87fb\u7269\u7a2e\u7684\u4e0d\u540c\u898f\u6a21\u5927\u5c0f\u7684\u7fa4\u843d\uff0c\u8403\u53d6\u879e\u87fb\u8eab\u4e0a\u7684\u5316\u5408\u7269\uff0c\u6aa2\u9a57\u662f\u5426\u5177\u6709\u6291\u5236\u8868\u76ae\u8461\u8404\u7403\u83cc\uff08Staphylococcus epidermidis<\/em>\uff09\u7684\u6d3b\u6027\u3002\u4ed6\u5011\u767c\u73fe\u5927\u7d04\u670960%\u7684\u879e\u87fb\u7fa4\u843d\u6703\u7522\u751f\u6297\u83cc\u7269\u8cea\u505a\u70ba\u6291\u5236\u75c5\u83cc\u50b3\u64ad\u7684\u514d\u75ab\u80fd\u529b [1]\u3002\u56e0\u6b64\uff0c\u5f9e\u9019\u4e9b\u879e\u87fb\u8eab\u4e0a\u627e\u5230\u7684\u6297\u83cc\u7269\u8cea\u6210\u70ba\u6211\u5011\u627e\u5c0b\u65b0\u578b\u6297\u751f\u7d20\u85e5\u7269\u7684\u5e0c\u671b\u3002<\/p>\n

\u7136\u800c\uff0c\u9019\u4e9b\u672a\u77e5\u7684\u6297\u83cc\u7269\u8cea\u662f\u4ec0\u9ebc\u6a23\u7684\u5316\u5408\u7269\u5462\uff1f\u9019\u662f\u4e00\u500b\u68d8\u624b\u7684\u96e3\u984c\u3002\u4f86\u81ea\u5a01\u65af\u5eb7\u8f9b\u9ea5\u8fea\u905c\u5206\u6821\u7d30\u83cc\u5b78\u7cfbCameron Currie \u6559\u6388\u7684\u5718\u968a\u6700\u65b0\u767c\u8868\u5728\u81ea\u7136\u901a\u8a0a\uff08Nature Communications\uff09\u4e0a\u7684\u4e00\u9805\u7814\u7a76\u8b93\u6211\u5011\u770b\u898b\u4e86\u4e00\u9053\u66d9\u5149\u3002Currie\u6559\u6388\u7684\u5718\u968a\u5efa\u7acb\u4e00\u5957\u5b8c\u6574\u7684\u5206\u6790\u6d41\u7a0b\uff0c\u8a55\u4f30\u4f86\u81ea\u879e\u87fb\u8eab\u4e0a\u7684\u93c8\u9ef4\u83cc\uff08Streptomyces\uff09\u4e2d\u627e\u51fa\u4e00\u7a2e\u65b0\u7a4e\u7684\u6297\u751f\u7d20\u85e5\u7269 [2]\u3002<\/p>\n

\u5927\u591a\u6578\u6297\u751f\u7d20\u85e5\u7269\u90fd\u662f\u5f9e\u751f\u6d3b\u5728\u571f\u58e4\u4e2d\u7684\u7d30\u83cc\u4e2d\u767c\u73fe\u7684\uff0c\u53ea\u662f\u76ee\u524d\u8981\u5f9e\u571f\u58e4\u7d30\u83cc\u627e\u51fa\u65b0\u578b\u7684\u6297\u751f\u7d20\u5c31\u50cf\u662f\u7de3\u6728\u6c42\u9b5a\u822c\u56f0\u96e3\u3002<\/p>\n

\u93c8\u9ef4\u83cc\u5927\u7d04\u8d77\u6e90\u65bc3.8\u5104\u5e74\u524d\uff0c\u5f8c\u4f86\u6f14\u5316\u51fa\u8a31\u591a\u7684\u5206\u652f\uff0c\u5176\u4e2d\u4e00\u4e9b\u5e38\u898b\u65bc\u571f\u58e4\u4e2d\uff0c\u4e00\u4e9b\u5247\u8ddf\u6606\u87f2\u5171\u540c\u751f\u6d3b\u3002\u7d93\u904e\u9577\u6642\u9593\u7684\u6f14\u5316\uff0c\u8207\u6606\u87f2\u5171\u751f\u7684\u93c8\u9ef4\u83cc\u5df2\u7d93\u767c\u5c55\u51fa\u8207\u571f\u58e4\u93c8\u9ef4\u83cc\u622a\u7136\u4e0d\u540c\u7684\u5c6c\u6027\u3002<\/p>\n

Currie\u6559\u6388\u7684\u7814\u7a76\u5718\u968a\u9996\u5148\u5c0d\u4f86\u81ea\u5317\u7f8e\u548c\u5357\u7f8e\u4e0d\u540c\u74b0\u5883\u76841,400\u591a\u7a2e\u6606\u87f2\u8eab\u4e0a\u627e\u5230\u7684\u93c8\u9ef4\u83cc\u7684\u83cc\u682a\u9032\u884c\u8a73\u76e1\u7684\u641c\u7d22\u8ddf\u8a66\u9a57\uff0c\u4ed6\u5011\u767c\u73fe\u4f86\u81ea\u6606\u87f2\u7684\u93c8\u9ef4\u83cc\u7a2e\u985e\u76f8\u8f03\u65bc\u5176\u4ed6\u5f9e\u571f\u58e4\u6216\u690d\u7269\u4e2d\u627e\u5230\u7684\uff0c\u80fd\u66f4\u6709\u6548\u5730\u6291\u5236\u75c5\u539f\u9ad4\u7684\u751f\u9577\u3002<\/p>\n

\u63a5\u8457\uff0c\u4ed6\u5011\u5206\u6790\u4e26\u6bd4\u8f03\u9019\u7fa4\u6606\u87f2\u95dc\u806f\u7684\u93c8\u9ef4\u83cc\u57fa\u56e0\u7d44\u5e8f\u5217\uff0c\u6210\u529f\u5730\u7834\u89e3\u51fa\u5176\u4e2d\u4e00\u7fa4\u7279\u6b8a\u7684\u57fa\u56e0\u662f\u7528\u4f86\u7522\u751f\u9019\u985e\u6297\u83cc\u5316\u5408\u7269\uff0c\u4e26\u7528\u8cea\u8b5c\u5100\u89e3\u6790\u5316\u5408\u7269\u4f86\u78ba\u8a8d\u5206\u5b50\u7d50\u69cb\u4e0a\u7684\u5dee\u7570\u3002<\/p>\n

\u6700\u5f8c\uff0c\u4ed6\u5011\u5f9e\u4e00\u7a2e\u4f86\u81ea\u5df4\u897f\u5c08\u9580\u990a\u6b96\u771f\u83cc\u7684\u879e\u87fb\uff08Cyphomyrmex sp.<\/em>\uff09\u8eab\u4e0a\u4e4b\u93c8\u9ef4\u83cc\u7d14\u5316\u51fa\u4e00\u500b\u65b0\u578b\u6297\u751f\u7d20\uff0c\u547d\u540d\u70bacyphomycin \u3002 \u5728\u5c0f\u9f20\u7684\u8a66\u9a57\u4e2d\uff0ccyphomycin\u53ef\u4ee5\u6210\u529f\u5730\u6cbb\u7642\u88ab\u767d\u8272\u5ff5\u73e0\u83cc\uff08Candida albicans<\/em>\uff09\u7684\u611f\u67d3\u3002\u9019\u7a2e\u767d\u8272\u5ff5\u73e0\u83cc\u662f\u4e00\u7a2e\u4f3a\u6a5f\u6027\u611f\u67d3\u7684\u81f4\u75c5\u771f\u83cc\uff0c\u8b93\u514d\u75ab\u529f\u80fd\u4f4e\u4e0b\u60a3\u8005\u751f\u75c5\u3002\u800c\u4e14cyphomycin \u5c0d\u65bc\u5c0f\u9f20\u662f\u4f4e\u6bd2\u6027\u4e0d\u6703\u5f15\u8d77\u526f\u4f5c\u7528\u3002\u57fa\u65bc\u5728\u5c0f\u9f20\u521d\u671f\u8a66\u9a57\u7684\u6210\u6548\u8b93\u7814\u7a76\u4eba\u54e1\u5df2\u7d93\u91dd\u5c0dcyphomycin\u63d0\u51fa\u5c08\u5229\uff0c\u671f\u5f85\u958b\u767c\u7528\u5728\u4eba\u985e\u81e8\u5e8a\u4f7f\u7528\u7684\u65b0\u578b\u6297\u751f\u7d20\u3002<\/p>\n

\u9019\u7bc7\u8de8\u9818\u57df\u7684\u7814\u7a76\u6210\u529f\u5730\u514b\u670d\u5f9e\u6606\u87f2\u95dc\u806f\u7684\u5fae\u751f\u7269\u4e2d\u6311\u9078\u51fa\u65b0\u578b\u6297\u751f\u7d20\u7684\u96e3\u984c\u3002\u96d6\u7136\uff0c\u8ddd\u96e2\u81e8\u5e8a\u8a66\u9a57\u7528\u85e5\u9084\u6709\u597d\u9577\u7684\u958b\u767c\u4e4b\u8def\uff0c\u66f4\u91cd\u8981\u7684\u662f\u6301\u7e8c\u5728\u521d\u671f\u7be9\u9078\u51fa\u66f4\u591a\u6709\u6f5b\u529b\u7684\u5316\u5408\u7269\u3002\u773e\u591a\u7684\u6606\u87f2\u7a2e\u985e\u7d66\u6211\u5011\u5f88\u591a\u6a5f\u6703\u7e7c\u7e8c\u53bb\u63a2\u7d22\uff01<\/p>\n

 <\/p>\n

\u53c3\u8003\u6587\u737b<\/strong><\/p>\n

    \n
  1. Penick CA, Halawani O, Pearson B, Mathews S, L\u00f3pez-Uribe MM, Dunn RR, et al. External immunity in ant societies: sociality and colony size do not predict investment in antimicrobials. R Soc Open Sci. The Royal Society Publishing; 2018;5: 171332. doi:10.1098\/rsos.171332<\/li>\n
  2. Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, et al. The antimicrobial potential of Streptomyces from insect microbiomes. Nat Commun. Nature Publishing Group; 2019;10: 516. doi:10.1038\/s41467-019-08438-0<\/li>\n<\/ol>\n

    --
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