{"id":31334,"date":"2018-08-02T00:55:22","date_gmt":"2018-08-01T16:55:22","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=31334"},"modified":"2019-09-17T13:09:45","modified_gmt":"2019-09-17T05:09:45","slug":"%e3%80%90%e6%8e%a2%e7%b4%a219-8%e3%80%91%e5%ae%a2%e8%a3%bd%e4%bd%a0%e7%9a%84%e5%81%a5%e5%ba%b7%ef%bc%9a%e8%ab%87%e5%9f%ba%e5%9b%a0%e3%80%81%e9%ab%94%e8%b3%aa%e8%88%87%e7%b2%be%e6%ba%96%e9%86%ab","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=31334","title":{"rendered":"\u3010\u63a2\u7d2219-8\u3011\u5ba2\u88fd\u4f60\u7684\u5065\u5eb7\uff1a\u8ac7\u57fa\u56e0\u3001\u9ad4\u8cea\u8207\u7cbe\u6e96\u91ab\u5b78"},"content":{"rendered":"<p><strong>\u8b1b\u5e2b\uff5c\u967d\u660e\u5927\u5b78\u57fa\u56e0\u9ad4\u79d1\u5b78\u7814\u7a76\u6240\u6559\u6388 \u5468\u6210\u529f<\/strong><br \/>\n<strong>\u5f59\u6574\u64b0\u6587\uff5c\u6c88\u541b\u5b9c<\/strong><\/p>\n<p>\u300c\u4eba\u985e\u57fa\u56e0\u7d44\u8a08\u756b\u300d\u57282003\u5e74\u5df2\u544a\u7ae3\u5de5\uff1b\u4f46\u6211\u5011\u8a72\u7576\u62ff\u9019\u7d04\u83ab\u5169\u842c\u500b\u57fa\u56e0\u3001\u4e09\u5341\u4e00\u5104\u500b\u9e7c\u57fa\u600e\u9ebc\u8fa6\uff1f<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u6c7a\u5b9a\u547d\u904b\u7684\u300c\u9ad4\u8cea\u300d<\/strong><\/span><\/p>\n<p>\u300c\u4eba\u4e4b\u7570\u65bc\u79bd\u7378\u8005\uff0c\u5e7e\u516e\uff01\u300d\u662f\u57fa\u56e0\u7d44\u89e3\u78bc\u5e36\u4f86\u7684\u9a5a\u559c\u4e4b\u4e00\u2014\u2014\u4e8b\u5be6\u4e0a\uff0c\u4eba\u985e\u8207\u9ed1\u7329\u7329\u7684\u57fa\u56e0\uff0c\u50c5\u7d04\u767e\u5206\u4e4b\u4e00\u9ede\u591a\u7684\u5dee\u7570\uff1b\u800c\u540c\u5c6c\u4eba\u985e\u7684\u500b\u9ad4\u4e4b\u9593\uff0c\u5dee\u7570\u81ea\u7136\u66f4\u5c11\u4e86\u3002\u7136\u800c\uff0c\u5982\u6b64\u5fae\u5c0f\u7684\u5dee\u7570\uff0c\u537b\u8db3\u4f7f\u4eba\u4eba\u7368\u4e00\u7121\u4e8c\uff1b\u9019\u4fbf\u8a72\u6b78\u529f\u65bc\u55ae\u6838\u82f7\u9178\u591a\u6a23\u6027\uff08single-nucleotide polymorphism\uff09\u300d\u4e86\u3002\u4e0d\u540c\u7684\u907a\u50b3\u5bc6\u78bc\uff0c\u7522\u751f\u4e86\u4e0d\u540c\u7684\u80fa\u57fa\u9178\uff0c\u9032\u800c\u5f71\u97ff\u4e86\u86cb\u767d\u8cea\u7d50\u69cb\uff0c\u4f7f\u5176\u529f\u80fd\u7565\u6709\u5dee\u7570\uff0c\u7531\u6b64\u7522\u751f\u4e0d\u540c\u7684\u8868\u73fe\u578b\u3002<!--more--><\/p>\n<p>\u8209\u4f8b\u800c\u8a00\uff0c\u6bcf\u500b\u4eba\u8eab\u908a\u7e3d\u6709\u5927\u80c3\u738b\u7626\u5b50\uff0c\u8207\u5f77\u5f7f\u547c\u5438\u90fd\u6703\u80d6\u7684\u670b\u53cb\u3002\u9019\u5f97\u6b78\u548e\u65bc\u6bcf\u500b\u4eba\u9ad4\u5167\u5c07\u8461\u8404\u7cd6\u8f49\u5316\u5408\u6210\u8102\u80aa\u9178\u7684\u901f\u5ea6\u4e0d\u4e00\uff0c\u6240\u7522\u751f\u4e4b\u8868\u73fe\u578b\u5dee\u7570\u3002DNA\u4e2d\u7684\u55ae\u6838\u82f7\u9178\u591a\u6a23\u6027\u5f77\u5f7f\u500b\u4eba\u9ad4\u5167\u7684\u6676\u7247\uff0c\u8a18\u9304\u4e86\u7368\u7279\u7684\u300c\u8eab\u5206\u8b49\u865f\u78bc\u300d\u3002\u5982\u6b64\u8aaa\u4f86\u4fbf\u8907\u96dc\u4e86\uff0c\u800c\u5176\u5be6\u6211\u5011\u7d93\u5e38\u4f7f\u7528\u4e00\u767d\u8a71\u7684\u8a5e\u5f59\u4f86\u8868\u9054\u9019\u500b\u6982\u5ff5\u2014\u2014\u6240\u8b02\u300c\u9ad4\u8cea\u300d\u3002\u5e73\u65e5\u88e1\u7e3d\u96e3\u514d\u8aaa\u5e7e\u53e5\u300c\u554a\uff0c\u4ed6\u5c31\u662f\u6613\u80d6\u9ad4\u8cea\u300d\u3001\u300c\u6211\u7684\u9ad4\u8cea\u5c31\u662f\u6015\u51b7\u300d\uff1b\u4f46\u4e8b\u5be6\u4e0a\uff0c\u5c11\u6709\u4eba\u8aaa\u5f97\u51fa\u9019\u300c\u9ad4\u8cea\u300d\u662f\u4ec0\u9ebc\u3002\u57fa\u56e0\u79d1\u5b78\u7684\u7814\u7a76\uff0c\u6070\u597d\u80fd\u548c\u9019\u7956\u5b97\u50b3\u4e0b\u4f86\u7684\u8aaa\u6cd5\u76f8\u4e92\u8f1d\u6620\u3002<\/p>\n<p>\u7d50\u5408\u4e86\u91ab\u5b78\u4ee5\u53ca\u6d41\u884c\u75c5\u5b78\uff0c\u6211\u5011\u53c8\u6709\u4e86\u66f4\u591a\u7684\u7591\u554f\u3002\u83f8\u76d2\u5ee3\u544a\u4e0a\u6035\u76ee\u9a5a\u5fc3\u7684\u300c\u62bd\u7159\u6703\u5c0e\u81f4\u80ba\u764c\u300d\uff0c\u4f46\u5be6\u969b\u4e0a\u96e3\u9053\u6240\u6709\u8001\u83f8\u69cd\u90fd\u7d42\u5c07\u7f79\u764c\uff1f\u7e3d\u6709\u4e0d\u5c11\u4e03\u516b\u5341\u6b72\u7684\u8001\u5148\u751f\u8001\u592a\u592a\uff0c\u4e0d\u53fc\u8457\u83f8\u5c31\u6e3e\u8eab\u4e0d\u5c0d\u52c1\uff0c\u4f46\u4f9d\u7136\u751f\u9f8d\u6d3b\u864e\uff0c\u6beb\u7121\u75be\u75c5\u8de1\u8c61\u3002\u54ea\u4e9b\u907a\u50b3\u8cc7\u8a0a\u6c7a\u5b9a\u4e86\u9019\u6a23\u7684\u300c\u9ad4\u8cea\u300d\uff1f\u6bd4\u8f03\u6027\u7814\u7a76\u6b78\u985e\u51fa\u5169\u7fa4\u4eba\uff0c\u5206\u5225\u662f\u9577\u671f\u62bd\u83f8\u5f8c\u5f97\u5230\u80ba\u764c\u3001\u4ee5\u53ca\u6c92\u6709\u5f97\u5230\u80ba\u764c\u7684\u4eba\u3002\u7d93\u7531\u5206\u6790\u5169\u7fa4\u4eba\u907a\u50b3\u8cc7\u8a0a\u4e4b\u5dee\uff0c\u6216\u53ef\u660e\u767d\u54ea\u4e9b\u57fa\u56e0\u5c0d\u5438\u83f8\u8005\u5f97\u5230\u80ba\u764c\u50be\u5411\u7684\u5f71\u97ff\u3002<\/p>\n<figure id=\"attachment_31342\" aria-describedby=\"caption-attachment-31342\" style=\"width: 490px\" class=\"wp-caption aligncenter\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-31342 size-full\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2018\/06\/19-8-pixabay-CC0-Creative-Commons.jpg\" alt=\"\" width=\"490\" height=\"340\"><figcaption id=\"caption-attachment-31342\" class=\"wp-caption-text\">CC0 Creative Commons<\/figcaption><\/figure>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u57fa\u56e0\u5b9a\u5e8f\u7b97\u51fa\u5065\u5eb7\u904b\uff1f<\/strong><\/span><\/p>\n<p>\u57fa\u56e0\u7d44\u8a08\u756b\u5b8c\u6210\u5f8c\uff0c\u6211\u5011\u958b\u59cb\u6709\u4e86\u500b\u60f3\u50cf\uff1a\u4e5f\u8a31\u6709\u671d\u4e00\u65e5\uff0c\u521d\u751f\u7684\u5b30\u5152\u9664\u4e86\u51fa\u751f\u8b49\u660e\u4e4b\u5916\uff0c\u9084\u53ef\u7372\u5f97\u4e00\u5f35\u5927\u8868\uff0c\u8a73\u9304\u4e86\u4ed6\u57fa\u56e0\u7d44\u4e2d\u5e36\u6709\u7684\u98a8\u96aa\u3001\u9700\u8981\u683c\u5916\u7576\u5fc3\u7684\u75be\u75c5\u3002\u4e26\u9032\u4e00\u6b65\u8b93\u4ed6\u80fd\u64ec\u5b9a\u751f\u6d3b\u7684\u6e96\u5247\u3001\u8da8\u5409\u907f\u51f6\u3002<\/p>\n<p>\u5341\u591a\u5e74\u7684\u5f8c\u57fa\u56e0\u7d44\u6642\u4ee3\uff0c\u79d1\u5b78\u5bb6\u4e86\u89e3\u7684\u53c8\u66f4\u591a\u4e86\u3002\u57fa\u56e0\u9060\u4e0d\u6b62\u300c\u7236\u6bcd\u5404\u4f9b\u61c9\u4e00\u689d\u67d3\u8272\u9ad4\u300d\u822c\u76f4\u89c0\u3002\u57fa\u56e0\u7d44\u591a\u6a23\u6027\uff08genomic polymorphism\uff09\u9664\u4e86\u55ae\u6838\u82f7\u9178\u8b8a\u7570\u4e4b\u5916\uff0c\u57fa\u56e0\u5e8f\u5217\u62f7\u8c9d\u7d44\u6578\u591a\u6a23\u6027\uff08copy number variation\uff09\u7684\u89d2\u8272\u4ea6\u6d6e\u4e0a\u6aaf\u9762\u3002\u7e3d\u8aaa\u5403\u98ef\u7687\u5e1d\u5927\uff0c\u4e0d\u540c\u65cf\u7fa4\u98f2\u98df\u7fd2\u6163\u7684\u5dee\u7570\uff0c\u5f9e\u553e\u6db2\u4e2d\u7684\u6fb1\u7c89\u6c34\u89e3\u9176\u53ef\u898b\u86db\u7d72\u99ac\u8de1\u3002\u7814\u7a76\u986f\u793a\uff0c\u98df\u7269\u4e2d\u6fb1\u7c89\u542b\u91cf\u591a\u7684\u65cf\u7fa4\uff08\u4f8b\u5982\u65e5\u672c\u4eba\uff09\uff0c\u6bd4\u8d77\u98f2\u98df\u4e2d\u6fb1\u7c89\u6bd4\u4f8b\u8f03\u4f4e\u7684\u65cf\u7fa4\uff0c\u5176\u6fb1\u7c89\u9176\u57fa\u56e0\u5e8f\u5217\u62f7\u8c9d\u7d44\u6578\u986f\u8457\u8f03\u591a\uff01<\/p>\n<p>\u56de\u5230\u75be\u75c5\u8207\u57fa\u56e0\u7684\u95dc\u806f\u6027\uff0c\u6211\u5011\u53ef\u4ee5\u505a\u500b\u7c21\u55ae\u5047\u8a2d\uff1a\u82e5\u67d0\u75be\u75c5\u65cf\u7fa4\u7684\u67d0\u4e00\u7d44\u57fa\u56e0\u578b\uff0c\u4ee5A1G1\u70ba\u591a\uff0c\u800c\u6b63\u5e38\u70ba\u7f79\u75c5\u65cf\u7fa4\u4e2d\uff0cA2G2\u7684\u6bd4\u4f8b\u8f03\u9ad8\uff0c\u5247A1G1\u57fa\u56e0\u8b8a\u7570\u53ef\u80fd\u8207\u75be\u75c5\u76f8\u95dc\u3002\u7576\u7136\uff0c\u4e0b\u4e00\u6b65\u4fbf\u662f\u63a2\u8a0eA1G1\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u662f\u5426\u80fd\u5408\u7406\u89e3\u91cb\u5e36\u6709\u6b64\u57fa\u56e0\u7684\u4eba\uff0c\u8f03\u5bb9\u6613\u5f97\u75c5\u3002<\/p>\n<p>\u62ff\u6297\u611b\u6ecb\u85e5\u7269Abacavir\u4f86\u8aaa\uff0c\u5c0d\u65bc\u5c11\u6578\u4eba\u800c\u8a00\uff0c\u5b83\u6703\u5c0e\u81f4\u56b4\u91cd\u7684\u904e\u654f\u53cd\u61c9\u3002\u7a76\u7adf\u4ec0\u9ebc\u57fa\u56e0\u8207\u6b64\u56b4\u91cd\u53cd\u61c9\u76f8\u95dc\uff1f\u5f8c\u4f86\u7684\u7814\u7a76\u767c\u73fe\uff0c\u662fHLA-B*5701\u57fa\u56e0\u9020\u6210\u514d\u75ab\u7cfb\u7d71\u7684\u8b8a\u7570\u3002\u9019\u500b\u57fa\u56e0\u5728\u4e0d\u540c\u65cf\u7fa4\u4e2d\u5b58\u5728\u7684\u6bd4\u4f8b\u5927\u6709\u4e0d\u540c\uff0c\u5370\u5ea6\u65cf\u88d4\u53ef\u9ad8\u905410%\uff0c\u897f\u6b50\u4e5f\u67095~7%\uff0c\u4f46\u65e5\u672c\u537b\u903c\u8fd1\u65bc0%\u3002\u53e6\u4e00\u500b\u4f8b\u5b50\u662f\u7531\u9673\u57a3\u5d07\u6559\u6388\u8207\u4e2d\u7814\u9662\u5408\u4f5c\uff0c\u7814\u7a76\u6297\u7672\u7647\u85e5Carbemazepine\u5728\u7279\u5b9a\u4eba\u8eab\u4e0a\u6240\u5f15\u767c\u7684\u5f37\u70c8\u6bd2\u6027\u53cd\u61c9\uff0c\u7d50\u679c\u767c\u73feHLA-B*1502\u7684\u8b8a\u7570\u3002\u5982\u4eca\u9019\u500b\u57fa\u56e0\u6aa2\u6e2c\uff0c\u5df2\u7d93\u5728\u5065\u4fdd\u898f\u7bc4\u4e0b\uff0c\u6210\u70ba\u7528\u85e5\u524d\u7684\u4f8b\u884c\u516c\u4e8b\u3002<\/p>\n<p>\u4e0d\u4f46\u526f\u4f5c\u7528\u8207\u57fa\u56e0\u6709\u95dc\uff0c\u57fa\u56e0\u5c0d\u85e5\u7269\u7684\u300c\u4f5c\u7528\u300d\u4e5f\u6709\u6c7a\u5b9a\u6027\u7684\u5f71\u97ff\u3002\u6bd4\u5982C\u578b\u809d\u708e\u4f7f\u7528PegIFN-alpha-2Bb\u52a0\u4e0aribavirin\u7684\u6cbb\u7652\u7387\uff0c\u5c31\u8207IL28B\u4e0a\u4e00\u500b\u4f4d\u9ede\u7684\u5dee\u7570\u606f\u606f\u76f8\u95dc\u3002\u5176\u4e2d\u975e\u88d4\u7f8e\u570b\u4eba\u7684\u6cbb\u7652\u7387\u50c524%\uff0c\u9060\u905c\u65bc\u4e9e\u88d4\u768476%\u3002\u7d30\u7a76\u57fa\u56e0\u578b\uff0c\u4e9e\u88d4\u65cf\u7fa4\u5728\u6b64\u7b49\u4f4d\u57fa\u56e0\u4e0a\u70baC\u7684\u6bd4\u4f8b\uff0c\u8fd1\u4e4e\u767e\u5206\u4e4b\u767e\uff0c\u975e\u88d4\u5247\u53ea\u6709\u56db\u6210\u3002\u518d\u9032\u4e00\u6b65\u5206\u6790\uff0c\u82e5\u975e\u88d4\u7f8e\u570b\u4eba\u6b64\u7b49\u4f4d\u57fa\u56e0\u70baCC\uff0c\u5176\u6cbb\u7652\u7387\u4e5f\u6703\u6bd4\u540c\u65cf\u7fa4\u5e36\u6709TT\u6216TC\u8005\uff0c\u4f86\u5f97\u6a02\u89c0\u8a31\u591a\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u764c\u75c7\u7684\u524b\u661f\uff0c\u57fa\u56e0\u77e5\u9053\uff1f<\/strong><\/span><\/p>\n<p>\u7cbe\u6e96\u91ab\u5b78\u4e00\u500b\u7d55\u4f73\u7684\u4f8b\u5b50\uff0c\u662f\u767c\u5c55\u591a\u5e74\u7684\u764c\u75c7\u6a19\u9776\u85e5\u7269\u3002\u50b3\u7d71\u5316\u7642\u70ba\u4eba\u8a6c\u75c5\u4e4b\u8655\u4fbf\u662f\u597d\u58de\u901a\u6bba\uff0c\u800c\u6a19\u9776\u85e5\u7269\u5247\u6a19\u699c\u91dd\u5c0d\u764c\u7d30\u80de\u7684\u7f69\u9580\u3002\u6700\u7d93\u5178\u7684\u4f8b\u5b50\u662f\u6162\u6027\u9aa8\u9ad3\u6027\u767d\u8840\u75c5\uff08CML, chronic myelogenous leukemia\uff09\u3002\u7531\u65bc\u7b2c9\u8207\u7b2c22\u865f\u67d3\u8272\u9ad4\u7684\u4e92\u63db\uff0c\u7522\u751f\u4e86\u4e0d\u6b63\u5e38\u7684\u8cbb\u57ce\u67d3\u8272\u9ad4\uff08Philadelphia chromosome\uff09\uff0c\u9032\u800c\u88fd\u9020\u51fa\u4e0d\u6b63\u5e38\u7684\u81f4\u764c\u86cb\u767dBcr-Abl\u3002Bcr-Abl\u4e0d\u4f46\u6210\u70ba\u6162\u6027\u9aa8\u9ad3\u6027\u767d\u8840\u75c5\u7684\u751f\u7269\u6a19\u8a18\uff0c\u4ea6\u6210\u4e86\u85e5\u7269\u7684\u300c\u7bad\u9776\u300d\u3002\u6a19\u9776\u85e5Imatinib\u8207\u50b3\u7d71\u5316\u7642\u76f8\u6bd4\uff0c\u4e94\u5e74\u8ffd\u8e64\u7684\u6548\u679c\u662f\u61f8\u6b8a\u768483%\u6bd430%\u3002\u4f60\u6703\u554f\uff0c\u53e6\u5916\u768417%\u5462\uff1f\u9019\u7fa4\u5c0d\u6a19\u9776\u85e5\u7269\u7684\u53cd\u61c9\u4e0d\u4f73\u8005\u662f\u500b\u6cbb\u7642\u76f2\u9ede\uff0c\u4e5f\u53ef\u80fd\u662f\u4fc3\u4f7f\u9032\u4e00\u6b65\u7814\u7a76\u7684\u5951\u6a5f\u3002<\/p>\n<p>\u80ba\u764c\u6a19\u9776\u85e5Gefitinib\u5728\u65e5\u672c\u7684\u81e8\u5e8a\u5be6\u9a57\u4e2d\uff0c\u7e2e\u5c0f\u4e8650%\u75c5\u4eba\u7684\u816b\u7624\uff1b\u540c\u6a23\u7684\u85e5\u5728\u7f8e\u570b\uff0c\u50c5\u57285%\u7684\u4eba\u8eab\u4e0a\u898b\u6548\u3002\u79d1\u5b78\u5bb6\u627e\u4e0a\u4e86\u90195%\u7684\u4eba\uff0c\u5728\u4ed6\u5011\u7684\u816b\u7624\u4e0a\u767c\u73fe\u4e86\u5171\u901a\u9ede\u2014\u2014\u8868\u76ae\u751f\u9577\u56e0\u5b50EGFR\uff08epidermal growth factor\uff09\u4e0a\u7684\u985e\u4f3c\u7a81\u8b8a\u3002\u6771\u65b9\u7684\u4e9e\u6d32\u8207\u65e5\u672c\uff0c\u51fa\u73fe\u6b64\u57fa\u56e0\u8b8a\u7570\u7684\u6bd4\u4f8b\u8f03\u9ad8\uff1bGefitinib\u5728\u6771\u65b9\u7684\u89d2\u8272\uff0c\u662f\u4ee5\u66f4\u5f62\u91cd\u8981\u3002\u5982\u4eca\uff0c\u80ba\u817a\u764c\u75c5\u4eba\u5e7e\u4e4e\u5fc5\u5b9a\u505a\u764c\u7d30\u80de\u7684\u57fa\u56e0\u6aa2\u6e2c\uff0c\u722d\u53d6\u4f7f\u7528\u6a19\u9776\u85e5\u7269\u7684\u6a5f\u6703\u3002<\/p>\n<p>\u4eba\u985e\u662f\u5426\u5373\u5c07\u653b\u514b\u764c\u75c7\uff1f\u53ef\u60dc\u7684\u662f\uff0c\u96a8\u8457\u6a19\u9776\u85e5\u7269\u7684\u51fa\u73fe\uff0c\u764c\u7d30\u80de\u7684\u751f\u5b58\u4e4b\u9053\u5373\u662f\u52a0\u5feb\u7a81\u8b8a\u3001\u9078\u64c7\u51fa\u6297\u85e5\u6027\uff0c\u6210\u4e86\u6a19\u9776\u85e5\u7269\u7684\u60e1\u5922\u3002\u5f88\u591a\u75c5\u4eba\u4f7f\u7528\u6a19\u9776\u85e5\u7684\u521d\u671f\u53cd\u61c9\u7d55\u4f73\uff0c\u4e00\u6bb5\u6642\u9593\u5f8c\u537b\u53c8\u5175\u6557\u5982\u5c71\u5012\u3002<\/p>\n<p>\u5373\u4fbf\u5982\u6b64\uff0c\u4f5c\u70ba\u500b\u4eba\u5316\u3001\u7cbe\u6e96\u91ab\u5b78\u7684\u57fa\u790e\uff0c\u57fa\u56e0\u6aa2\u6e2c\u6280\u8853\u4ecd\u820a\u8e8d\u4e0a\u98a8\u53e3\u6d6a\u5c16\u3002\u5f9e\u7b28\u91cd\u5982\u6d17\u8863\u6a5f\u7684\u5927\u5c0f\uff0c\u5230\u80fd\u73a9\u5f04\u9f13\u638c\u4e4b\u9593\u7684\u8f15\u5de7\uff0c\u5149\u662f\u5728\u5916\u578b\u4e0a\u5c31\u9032\u6b65\u4e0d\u5c11\u3002\u6700\u65b0\u6a5f\u578b\u6eff\u4f48\u5948\u7c73\u5b54\u6d1e\uff0c\u672a\u6709DNA\u901a\u904e\u6642\u96fb\u6d41\u9806\u66a2\u6d41\u904e\uff1b\u4f46DNA\u51fa\u73fe\u6642\uff0c\u96a8\u8457ATCG\u5927\u5c0f\u4e0d\u4e00\uff0c\u6703\u5c0d\u96fb\u6d41\u7522\u751f\u4e0d\u540c\u7a0b\u5ea6\u7684\u5f71\u97ff\u3002<\/p>\n<p>\u66f4\u5be6\u969b\u8aaa\u4f86\uff0c\u5f9e\u5929\u50f9\u7684\u57fa\u56e0\u5b9a\u5e8f\uff0c\u5230\u53ea\u6d88\u4e00\u5343\u7f8e\u91d1\uff0c\u5c31\u53ef\u4ee5\u8cb7\u56de\u4f86\u4ee5USB\u7684\u5f62\u5f0f\u63a5\u4e0a\u500b\u4eba\u96fb\u8166\uff0c\u66f4\u662f\u9769\u547d\u6027\u7a81\u7834\u3002\u6b50\u5df4\u99ac\u7e3d\u7d71\u66f4\u66fe\u5728\u570b\u6703\u6f14\u8aaa\u4e2d\uff0c\u7279\u5225\u63d0\u53ca\u7cbe\u6e96\u91ab\u5b78\u7684\u555f\u52d5\uff08precisional medicine initiative\uff09\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u9ad4\u8cea\u7684\u5176\u4ed6\u7d44\u6210\uff1a\u8868\u89c0\u907a\u50b3\u8207\u5fae\u751f\u7269<\/strong><\/span><\/p>\n<p>\u6211\u5011\u5982\u4f55\u60f3\u50cf\u672a\u4f86\u7684\u91ab\u5b78\uff1f\u53ef\u80fd\u662f\u8d70\u9032\u8a3a\u9593\uff0c\u5148\u53d6\u5c11\u91cf\u7684DNA\uff08\u6216\u8a31\u53ea\u9700\u8981\u4e00\u6ef4\u8840\u6db2\uff09\uff0c\u9001\u4ea4\u6a5f\u5668\u5206\u6790\uff0c\u63d0\u4f9b\u500b\u4eba\u5316\u7684\u91ab\u5b78\u5efa\u8b70\u3002<\/p>\n<p>\u907a\u50b3\u8cc7\u8a0a\u7684\u591a\u6a23\u6027\uff0c\u80fd\u5426\u7b49\u540c\u65bc\u500b\u4eba\u7684\u300c\u9ad4\u8cea\u300d\uff1f\u73fe\u4ee3\u79d1\u5b78\u591a\u534a\u4e0d\u652f\u6301\u6b64\u8aaa\u3002\u7cbe\u5375\u7d50\u5408\u77ac\u9593\uff0c\u6c7a\u5b9a\u4e86\u6cf0\u534a\u7684\u9ad4\u8cea\uff1b\u7136\u800c\u7531\u7cbe\u5375\u5f62\u6210\u4e4b\u5f8c\u5230\u80ce\u5152\u767c\u5c55\u5b8c\u5168\u4e4b\u524d\uff0c\u74b0\u5883\u7684\u5f71\u97ff\u4ea6\u5982\u5f71\u96a8\u5f62\u3002\u300a\u81ea\u7136\u300b\uff08<em>Nature<\/em>\uff09\u96dc\u8a8c\u66fe\u4ee5\u4e00\u500b\u8073\u52d5\u7684\u6a19\u984c\u300c\u70ba\u7236\u4e4b\u904e\uff08The Sins of the Father\uff09\u300d\u4f86\u63cf\u8ff0\u89aa\u4ee3\u6240\u53d7\u7684\u74b0\u5883\u523a\u6fc0\uff0c\u53ef\u4ee5\u900f\u904e\u8868\u89c0\u907a\u50b3\u50b3\u627f\u7d66\u4e0b\u4e00\u4ee3\u30021973\u5e7410\u67081\u65e5\uff0c\u5fb7\u570b\u5c01\u9396\u4e86\u8377\u862d\u963f\u59c6\u65af\u7279\u4e39\u7684\u7ce7\u98df\u9032\u51fa\u53e3\uff0c\u9020\u6210\u56b4\u91cd\u7684\u98e2\u8352\u3002\u96d6\u8aaa\u8271\u56f0\uff0c\u4ecd\u6709\u4e0d\u5c11\u5b30\u5b69\u5728\u9019\u500b\u6642\u671f\u51fa\u751f\ufe54\u56f0\u82e6\u7684\u74b0\u5883\u662f\u5426\u5f71\u97ff\u9019\u4e9b\u5b69\u5b50\u7684\u672a\u4f86\u5065\u5eb7\uff1f\u9577\u671f\u7684\u8ffd\u8e64\u767c\u73fe\uff0c\u6709\u8f03\u9ad8\u6bd4\u4f8b\u7684\u4eba\u51fa\u73fe\u80f0\u5cf6\u7d20\u6297\u62d2\uff0c\u4e14\u8eab\u6750\u80a5\u80d6\u7684\u6bd4\u4f8b\u4ea6\u8f03\u9ad8\u3002\u6328\u9913\u7684\u6bcd\u9ad4\uff0c\u900f\u904eDNA\u7684\u7532\u57fa\u5316\uff0c\u9020\u5c31\u4e86\u52aa\u529b\u651d\u53d6\u990a\u5206\u7684\u80ce\u5152\uff0c\u9577\u5927\u5f8c\u4ecd\u4e0d\u5fd8\u7576\u5e74\u300c\u9913\u300d\u3002<\/p>\n<p>\u6211\u5011\u8eab\u4e0a\u7684\u907a\u50b3\u8cc7\u8a0a\uff0c\u7406\u7576\u662f\u7236\u6bcd\u7684\u50b3\u627f\ufe54\u7136\u5206\u6790\u4eba\u6b7b\u4ea1\u6642\u7684\u907a\u50b3\u8cc7\u8a0a\uff0c\u537b\u9060\u9060\u8d85\u904e\u7576\u5e74\u4f86\u81ea\u7236\u6bcd\u7684\u90e8\u5206\uff01\u7531\u6b64\u5f15\u9032\u4e00\u500b\u6709\u8da3\u7684\u5047\u8aaa\u2014\u2014\u9664\u4e86\u672c\u8eab\u64c1\u6709\u7684\u5341\u5146\u7d30\u80de\u5916\uff0c\u8207\u4eba\u9ad4\u5171\u751f\u7684\u3001\u591a\u9054\u4e5d\u5341\u5146\u7684\u5fae\u751f\u7269\uff08microbes\uff09\uff0c\u8207\u6211\u5011\u7684\u907a\u50b3\u8cc7\u8a0a\u4ea6\u6709\u4e92\u52d5\u3002\u8eab\u4e0a\u6bcf\u500b\u90e8\u4f4d\uff0c\u90fd\u6709\u9069\u5408\u751f\u5b58\u7684\u5fae\u751f\u7269\uff1b\u5b83\u5011\u7684\u57fa\u56e0\u6578\u7e3d\u548c\u53ef\u9054\u767e\u842c\uff0c\u4e5f\u5927\u52dd\u4eba\u9ad4\u7684\u57fa\u56e0\u7d44\u3002\u5fae\u751f\u7269\u7684\u4f5c\u7528\u7e41\u591a\uff0c\u6bd4\u5982\u5c07\u53e3\u670d\u85e5\u8f49\u63db\u6210\u6d3b\u6027\u4ee3\u8b1d\u7522\u7269\uff0c\u6216\u5c07\u5b83\u5011\u53bb\u6d3b\u6027\u5316\u3002\u7576\u7136\uff0c\u85e5\u7269\u7684\u4f5c\u7528\u4e5f\u96a8\u6bcf\u500b\u4eba\u8eab\u4e0a\u6240\u6709\u7684\u5fae\u751f\u7269\uff08microbiota\uff09\u4e0d\u540c\u800c\u5404\u7570\u5176\u8da3\u3002<\/p>\n<p>\u4ee4\u4eba\u7169\u60f1\u7684\u80a5\u80d6\u554f\u984c\uff0c\u9664\u537b\u57fa\u56e0\u3001\u98f2\u98df\u7fd2\u6163\u7684\u5f71\u97ff\uff0c\u8178\u9053\u5fae\u751f\u7269\u4e5f\u8209\u8db3\u8f15\u91cd\u3002\u82e5\u8001\u9f20\u5e36\u6709\u4e00\u500b\u80a5\u80d6\u57fa\u56e0ob\uff0c\u548c\u91ce\u751f\u8001\u9f20\u9ad4\u578b\u7121\u7570\uff1b\u5e36\u6709\u4e00\u5c0dob\uff0c\u5247\u9ad4\u578b\u8f03\u70ba\u80a5\u80d6\u3002\u57fa\u56e0\u5c0d\u9ad4\u578b\u7684\u5f71\u97ff\u65e9\u5c31\u7f6a\u8b49\u78ba\u947f\uff1b\u6709\u8da3\u7684\u662f\uff0c\u80a5\u80d6\u9f20\u8207\u4e00\u822c\u9f20\u7684\u8178\u9053\u83cc\u53e2\u4e5f\u5927\u4e0d\u76f8\u540c\uff0c\u800c\u4ee5\u786c\u76ae\u9580\u7d30\u83cc\uff08Firmicutes\uff09\u7684\u6bd4\u4f8b\u589e\u52a0\u6700\u70ba\u986f\u8457\u3002\u82e5\u4e0d\u8abf\u6574\u57fa\u56e0\uff0c\u6539\u4ee5\u897f\u5316\u98f2\u98df\u990a\u80d6\u5c0f\u9f20\uff0c\u7adf\u4e5f\u80fd\u5728\u8178\u9053\u4e2d\uff0c\u6709\u985e\u4f3c\u767c\u73fe\u3002\u8f03\u591a\u7684\u786c\u76ae\u9580\u7d30\u83cc\u662f\u5426\u69cb\u6210\u80a5\u80d6\u7684\u56e0\u7d20\u4e4b\u4e00\uff1f\u96d9\u80de\u80ce\u7814\u7a76\u63d0\u4f9b\u4e86\u4e9b\u8a31\u86db\u7d72\u99ac\u8de1\u3002<\/p>\n<p>\u4e00\u80d6\u4e00\u7626\u7684\u96d9\u80de\u80ce\u5144\u5f1f\/\u59d0\u59b9\u5076\u6709\u6240\u898b\uff0c\u7814\u7a76\u8005\u65bd\u884c\u300c\u5fae\u751f\u7269\u79fb\u690d\uff08microbiota transplant\uff09\u300d\u2014\u2014\u5206\u5225\u7531\u5169\u4eba\u7684\u7cde\u4fbf\u4e2d\u8403\u53d6\u51fa\u8178\u9053\u5fae\u751f\u7269\uff0c\u690d\u5165\u5c0f\u9f20\u5c0f\u9f20\u9ad4\u5167\u3002\u7d50\u679c\u7372\u5f97\u80a5\u80d6\u8005\u5fae\u751f\u7269\u7684\u5c0f\u9f20\uff0c\u5373\u4f7f\u540c\u6a23\u98df\u7528\u9ad8\u7e96\u7dad\u4f4e\u8102\u80aa\u98f2\u98df\uff0c\u4ecd\u96e3\u9003\u80a5\u80d6\u4e0b\u5834\uff0c\u771f\u771f\u662f\u300c\u559d\u6c34\u90fd\u6703\u80d6\u300d\u4e86\u3002<\/p>\n<p>\u8178\u9053\u5fae\u751f\u7269\u8207\u514d\u75ab\u7cfb\u7d71\u4e5f\u812b\u4e0d\u4e86\u5e72\u4fc2\u3002\u514d\u75ab\u7d30\u80de\u8207\u5fae\u751f\u7269\u9694\u8457\u8178\u58c1\u4e00\u7246\u4e4b\u9694\uff0c\u4e5f\u80fd\u5f7c\u6b64\u6e9d\u901a\u3002\u9019\u6a23\u7684\u4e92\u52d5\u95dc\u4fc2\u9032\u884c\u4e86\u7121\u6578\u5e74\uff0c\u537b\u96a8\u7576\u4eca\u706b\u7d05\u7684\u764c\u75c7\u514d\u75ab\u7642\u6cd5\uff08immunotherapy\uff09\u518d\u6b21\u8072\u540d\u5927\u566a\u3002\u7406\u8ad6\u4e0a\uff0c\u514d\u75ab\u7d30\u80de\u4e26\u975e\u7121\u6cd5\u6d88\u6ec5\u4e0d\u6b63\u5e38\u7d30\u80de\uff1b\u764c\u7d30\u80de\u7684\u624b\u6cd5\u4e4b\u4e00\uff0c\u4fbf\u662f\u906d\u9047\u514d\u75ab\u7d30\u80de\u6642\uff0c\u9664\u4e86\u672c\u8eab\u8868\u9732\u764c\u7d30\u80de\u8eab\u4efd\u7684\u8868\u9762\u6297\u539f\u5916\uff0c\u66f4\u81ea\u5e36\u4e00\u300c\u715e\u8eca\u300d\uff0c\u4f7f\u514d\u75ab\u7d30\u80de\u5f77\u5f7f\u7761\u8457\u4e00\u822c\uff0c\u4e0d\u555f\u52d5\u6bd2\u6bba\u3002 \u514d\u75ab\u7642\u6cd5\u7684\u6982\u5ff5\uff0c\u4fbf\u662f\u5229\u7528\u6297\u9ad4\u91dd\u5c0d\u6b64\u300c\u715e\u8eca\u300d\u9032\u884c\u62c6\u9664\u3002\u5927\u5922\u521d\u9192\u7684\u514d\u75ab\u7d30\u80de\uff0c\u5373\u53ef\u6062\u5fa9\u6e05\u9664\u816b\u7624\u7684\u5927\u696d\u3002\u53ef\u60f3\u800c\u77e5\uff0c\u514d\u75ab\u7642\u6cd5\u4e26\u975e\u5c0d\u6240\u6709\u60a3\u8005\u5747\u6709\u5947\u6548\uff1b\u4ee5\u5f80\u7e3d\u4ee5\u70ba\u8207\u764c\u75c7\u7d30\u80de\u672c\u8eab\u7a81\u8b8a\u6578\u76ee\u8f03\u6709\u95dc\uff0c\u8fd1\u5e74\u537b\u767c\u73fe\uff0c\u7b87\u4e2d\u5999\u8da3\u53c8\u626f\u4e0a\u8178\u9053\u5fae\u751f\u7269\u3002\u79d1\u5b78\u5bb6\u5206\u5225\u641c\u96c6\u4e86\u5c0d\u514d\u75ab\u7642\u6cd5\u53cd\u61c9\u4f73\u8207\u53cd\u61c9\u5dee\u7684\u75c5\u4eba\u4e4b\u7cde\u4fbf\uff0c\u690d\u5165\u816b\u7624\u5c0f\u9f20\u4e2d\u3002\u7d50\u679c\u767c\u73fe\uff0c\u524d\u8005\u53d7\u76ca\u65bc\u514d\u75ab\u6cbb\u7642\uff0c\u5f8c\u8005\u5247\u7121\u52d5\u65bc\u8877\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cfHappily Ever After?!<\/strong><\/span><\/p>\n<p>\u767c\u5c55\u795e\u901f\u7684\u7cbe\u6e96\u91ab\u5b78\uff0c\u9664\u4e86\u4f7f\u4eba\u985e\u53d7\u60e0\u4e4b\u5916\uff0c\u81ea\u4e5f\u5e36\u4f86\u6311\u6230\u3002\u9996\u5148\uff0c\u6771\u65b9\u4eba\u8207\u897f\u65b9\u4eba\u7684\u300c\u9ad4\u8cea\u300d\u5927\u4e0d\u76f8\u540c\uff01\u300c\u897f\u91ab\u300d\u9867\u540d\u601d\u7fa9\u8d77\u7de3\u65bc\u897f\u65b9\uff0c\u8a31\u591a\u7814\u7a76\u6210\u679c\u4e5f\u4f86\u81ea\u897f\u65b9\u7684\u6587\u737b\uff0c\u7a76\u7adf\u9069\u7528\u65bc\u6771\u65b9\u4eba\u5426\uff1f2009\u5e74\uff0c\u5168\u57fa\u56e0\u7d44\u95dc\u806f\u5206\u6790\uff08GWAS, genome-wide association studies\uff09\u7684373\u7bc7\u7814\u7a76\u4e2d\uff0c\u6db5\u84cb\u4e86170\u842c\u4eba\uff0c\u5176\u4e2d\u537b\u50c54%\u70ba\u975e\u6b50\u6d32\u65cf\u88d4\uff1b\u5230\u4e862016\u5e74\uff0c\u591a\u90543500\u842c\u4eba\u7684\u5206\u6790\u4e2d\uff0c\u6b64\u6578\u64da\u5c0f\u5347\u523016%\u3002\u6771\u65b9\u4eba\u7684\u8cc7\u6599\u5eab\uff0c\u9084\u662f\u5f97\u4f9d\u9760\u81ea\u8eab\u7684\u7814\u7a76\u4f86\u8fce\u982d\u8d95\u4e0a\u4e86\u3002<\/p>\n<p>\u53e6\u4e00\u500b\u6311\u6230\u5247\u4f86\u81ea\u4eba\u985e\u5c0d\u751f\u547d\u8907\u96dc\u7cfb\u7d71\u4e4b\u6b20\u7f3a\u5b8c\u6574\u8a8d\u8b58\u3002\u8209\u4f8b\u800c\u8a00\uff0c\u4e59\u578b\u963b\u65b7\u5291\uff08beta-blocker\uff09Propranolol \u5c0d\u9810\u9632\u5fc3\u81df\u75c5\u6548\u679c\u7684\u7814\u7a76\u4e2d\uff0c\u7d71\u8a08\u986f\u793a\u572824\u500b\u6708\u7684\u8ffd\u8e64\u671f\u5167\uff0c\u670d\u85e5\u7d44\u6bd4\u8d77\u5c0d\u7167\u7d44\u7684\u6b7b\u4ea1\u7387\u5c11\u4e862.6%\uff087.2% v.s. 9.8%\uff09\u3002\u9019\u6a23\u7684\u7d50\u679c\u80fd\u5426\u7b49\u540c\u65bc\u6bcf\u500b\u4eba\u670d\u85e5\u5f8c\u7684\u6b7b\u4ea1\u7387\u6e1b\u5c112.6%\uff1f\u5176\u4e2d\u4ecd\u6709\u592a\u591a\u672a\u77e5\u6578\u3002<\/p>\n<p>\u904e\u53bb\u5341\u5e74\uff0c\u6a19\u9776\u85e5\u7269\u84ec\u52c3\u767c\u5c55\uff0c\u4f46\u5be6\u969b\u53d7\u60e0\u7684\u764c\u75c7\u75c5\u4eba\uff0c\u537b\u4e0d\u52305%\u3002\u66f4\u9707\u64bc\u7684\u5927\u7d04\u662f\uff0c2002\u5e74\u52302014\u5e74\u7f8e\u570b\u98df\u54c1\u85e5\u7269\u7ba1\u7406\u5c40\u901a\u904e\u768471\u7a2e\u6297\u764c\u6a19\u9776\u85e5\uff0c\u5e73\u5747\u50c5\u5ef6\u9577\u764c\u75c7\u75c5\u4eba\u751f\u547d2.5\u500b\u6708\u3002\u80cc\u5f8c\u4ecd\u6709\u8a31\u591a\u672a\u89e3\u4e4b\u8b0e\uff0c\u4e0d\u514d\u4f7f\u7cbe\u6e96\u91ab\u5b78\u5099\u53d7\u8cea\u7591\u3002\u7a76\u7adf\u5b83\u662f\u5c0d\u672a\u4f86\u6a02\u89c0\u7684\u5141\u8afe\u3001\u6291\u6216\u50c5\u662f\u653f\u6cbb\u7092\u4f5c\uff1f\u6539\u5584\u4eba\u985e\u5065\u5eb7\u7684\u9762\u5411\u773e\u591a\uff0c\u5305\u62ec\u9810\u9632\u91ab\u5b78\u7684\u63d0\u5021\u3001\u91ab\u7642\u8cc7\u6e90\u7684\u666e\u53ca\uff0c\u90fd\u4e0d\u662f\u7aae\u6975\u6240\u6709\u65b0\u8208\u7642\u6cd5\u5c31\u80fd\u9054\u6210\u7684\u3002<\/p>\n<p>\u7cbe\u6e96\u91ab\u5b78\u80fd\u5426\u6210\u70ba\u4eba\u985e\u7684\u798f\u97f3\uff1f\u6216\u8a31\u8207DNA\u7684\u76e4\u6839\u932f\u7bc0\u4e00\u6a23\u6df1\u5967\u5f85\u89e3\u3002<\/p>\n<p><strong>--<br \/>\n\u672c\u6587\u6574\u7406\u81ea\uff1a107\/06\/09\u7531\u5468\u6210\u529f\u8001\u5e2b\u5728\u81fa\u5927\u601d\u4eae\u9928\u570b\u969b\u6703\u8b70\u5ef3\u6240\u4e3b\u8b1b\u4e4b\u300c<a href=\"https:\/\/youtu.be\/q0WZwIULOvQ\" target=\"_blank\" rel=\"noopener noreferrer\">\u57fa\u56e0\u3001\u9ad4\u8cea\u8207\u7cbe\u6e96\u91ab\u5b78<\/a>\u300d\u6f14\u8b1b\u5167\u5bb9\u3002<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0\u83f8\u76d2\u5ee3\u544a\u4e0a\u6035\u76ee\u9a5a\u5fc3\u7684\u300c\u62bd\u7159\u6703\u5c0e\u81f4\u80ba\u764c\u300d\uff0c\u4f46\u5be6\u969b\u4e0a\u96e3\u9053\u6240\u6709\u8001\u83f8\u69cd\u90fd\u7d42\u5c07\u7f79\u764c\uff1f\u7e3d\u6709\u4e0d\u5c11\u4e03\u516b\u5341\u6b72\u7684\u8001\u5148\u751f\u8001\u592a\u592a\uff0c\u4e0d\u53fc\u8457\u83f8\u5c31\u6e3e\u8eab\u4e0d\u5c0d\u52c1\uff0c\u4f46\u4f9d\u7136\u751f\u9f8d\u6d3b\u864e\uff0c\u6beb\u7121\u75be\u75c5\u8de1\u8c61\u3002\u54ea\u4e9b\u907a\u50b3\u8cc7\u8a0a\u6c7a\u5b9a\u4e86\u9019\u6a23\u7684\u300c\u9ad4\u8cea\u300d\uff1f\u6bd4\u8f03\u6027\u7814\u7a76\u6b78\u985e\u51fa\u5169\u7fa4\u4eba\uff0c\u5206\u5225\u662f\u9577\u671f\u62bd\u83f8\u5f8c\u5f97\u5230\u80ba\u764c\u3001\u4ee5\u53ca\u6c92\u6709\u5f97\u5230\u80ba\u764c\u7684\u4eba\u3002\u7d93\u7531\u5206\u6790\u5169\u7fa4\u4eba\u907a\u50b3\u8cc7\u8a0a\u4e4b\u5dee\uff0c\u6216\u53ef\u660e\u767d\u54ea\u4e9b\u57fa\u56e0\u5c0d\u5438\u83f8\u8005\u5f97\u5230\u80ba\u764c\u50be\u5411\u7684\u5f71\u97ff\u3002<\/p>\n","protected":false},"author":20,"featured_media":31342,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,3749],"tags":[1740,129,3920,3918],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2018\/06\/19-8-pixabay-CC0-Creative-Commons.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/31334"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=31334"}],"version-history":[{"count":8,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/31334\/revisions"}],"predecessor-version":[{"id":32781,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/31334\/revisions\/32781"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/31342"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=31334"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=31334"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=31334"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}