{"id":30408,"date":"2018-05-18T00:43:29","date_gmt":"2018-05-17T16:43:29","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=30408"},"modified":"2018-07-29T19:32:59","modified_gmt":"2018-07-29T11:32:59","slug":"%e3%80%90%e4%ba%ba%e7%89%a9%e5%b0%88%e8%a8%aa%e3%80%91%e7%94%9f%e5%91%bd%e7%a7%91%e5%ad%b8%e6%98%af%e6%b0%b8%e7%84%a1%e6%ad%a2%e5%a2%83%e7%9a%84%e9%81%93%e8%b7%af-%e8%a8%aa%e6%b2%88","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=30408","title":{"rendered":"\u3010\u4eba\u7269\u5c08\u8a2a\u3011\u751f\u547d\u79d1\u5b78\u662f\u6c38\u7121\u6b62\u5883\u7684\u9053\u8def\u2014\u2014\u8a2a\u6c88\u54f2\u9be4\u8001\u5e2b"},"content":{"rendered":"<p><strong><span style=\"color: #008080;\">\u25cf6\/02 \u6c88\u54f2\u9be4\u8001\u5e2b\u4e3b\u8b1b\uff1a\u300c\u8868\u89c0\u907a\u50b3\u5b78\u7684\u91cd\u8981\u89d2\u8272\uff1a\u5e73\u53cd\u62c9\u99ac\u514b\uff1f\u300d<\/span><a href=\"http:\/\/caseregister.ntu.edu.tw\/ntucaseweb\/pages\/searchDetail.jsp?datatype=2&amp;id=C1201801&amp;detNo=C120180107&amp;searchType=1&amp;word=&amp;classType=0\" target=\"_blank\" rel=\"noopener noreferrer\">\u9ede\u6b64\u5831\u540d<\/a><\/strong><\/p>\n<p><strong><img fetchpriority=\"high\" decoding=\"async\" class=\"alignleft wp-image-30894\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2018\/05\/19-7a.jpg\" alt=\"\" width=\"450\" height=\"312\" \/>\u63a1\u8a2a\u3001\u64b0\u6587\uff5c\u7c21\u5143\u7426<\/strong><\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u8207\u751f\u547d\u79d1\u5b78\u4e0d\u8b8a\u7684\u60c5\u8abc<\/strong><\/span><\/p>\n<p>\u6c88\u54f2\u9be4\u8001\u5e2b\u5728\u9ad8\u4e2d\u6642\u671f\u56e0\u70ba\u4e00\u500b\u751f\u7269\u8001\u5e2b\u6709\u8da3\u7684\u8b1b\u8ab2\u65b9\u5f0f\u800c\u5c0d\u6b64\u9818\u57df\u7522\u751f\u6fc3\u539a\u7684\u8208\u8da3\uff0c\u672a\u4f86\u60f3\u8981\u8d70\u751f\u7269\u7814\u7a76\u9019\u4e00\u884c\uff0c\u5118\u7ba1\u7576\u6642\u9084\u4e0d\u77e5\u9053\u751f\u7269\u7814\u7a76\u662f\u4ec0\u9ebc\u3001\u8981\u505a\u54ea\u4e00\u65b9\u9762\u7684\u7814\u7a76\u3002\u9078\u586b\u5927\u5b78\u5fd7\u9858\u6642\uff0c\u8001\u5e2b\u5dee\u4e00\u9ede\u9078\u4e86\u53f0\u5927\u52d5\u7269\u7cfb\uff0c\u4f46\u6700\u5f8c\u9084\u662f\u89ba\u5f97\u5f9e\u5206\u5b50\u5c64\u9762\u4f86\u9032\u884c\u751f\u7269\u7814\u7a76\u6703\u5c0d\u5c07\u4f86\u6bd4\u8f03\u6709\u7528\uff0c\u800c\u9078\u64c7\u4e86\u53f0\u5927\u5316\u5b78\u7cfb\u3002\u5c31\u8b80\u53f0\u5927\u5316\u5b78\u7cfb\u6642\uff0c\u8001\u5e2b\u4ecd\u937e\u60c5\u65bc\u751f\u547d\u79d1\u5b78\u65b9\u9762\uff0c\u7136\u56e0\u8ab2\u7a0b\u5b89\u6392\u7de3\u6545\uff0c\u5927\u4e09\u6642\u624d\u80fd\u4fee\u7fd2\u751f\u7269\u5316\u5b78\uff0c\u5c0e\u81f4\u6709\u4e9b\u751f\u7269\u76f8\u95dc\u8ab2\u7a0b\u56e0\u6c92\u6709\u5148\u4fee\u7fd2\u904e\u57fa\u790e\u8ab2\u7a0b\u800c\u906d\u64cb\u4fee\u3002\u56e0\u6b64\u5728\u5927\u5b78\u7562\u696d\u5f8c\uff0c\u8001\u5e2b\u7279\u5225\u5c0b\u627e\u6709\u9032\u884c\u751f\u547d\u79d1\u5b78\u76f8\u95dc\u7814\u7a76\u7684\u5316\u5b78\u7cfb\u7814\u7a76\u6240\u653b\u8b80\uff0c\u800c\u7f8e\u570b\u67cf\u514b\u840a\u5927\u5b78\u5316\u5b78\u7cfb\u7576\u6642\u6709\u4e09\u4f4d\u8001\u5e2b\u7684\u7814\u7a76\u65b9\u5411\u8207\u751f\u7269\u76f8\u95dc\u3002\u5176\u4e2d\u6c88\u8001\u5e2b\u5370\u8c61\u7279\u5225\u6df1\u523b\u7684\u662f\uff0c\u7576\u4ed6\u53c3\u89c0John Hearst\u7684\u5be6\u9a57\u5ba4\u6642\uff0c\u770b\u5230\u90a3\u88e1\u990a\u4e86\u5f88\u591a\u52d5\u7269\uff0c\u4fbf\u9078\u64c7\u4e86\u4ed6\u7684\u5be6\u9a57\u5ba4\u3002<!--more--><\/p>\n<p>\u653b\u8b80\u535a\u58eb\u6642\uff0c\u6c88\u8001\u5e2b\u7814\u7a76\u7684\u5c0d\u8c61\u662f\u4e00\u7a2e\u74b0\u72c0\u7684\u6709\u6a5f\u5316\u5408\u7269\u2014\u2014\u88dc\u9aa8\u8102\u7d20(Psoralen)\uff0c\u5e38\u7528\u65bc\u6cbb\u7642\u76ae\u819a\u861a\u3002\u6b64\u74b0\u72c0\u5316\u5408\u7269\u53ef\u4ee5\u9472\u5d4c\u81f3DNA\u88e1\u9762\uff0c\u5c07DNA\u96d9\u80a1\u4ee5\u5171\u50f9\u9375\u9023\u63a5\u8d77\u4f86\uff0c\u6c88\u8001\u5e2b\u5229\u7528\u6b64\u6027\u8cea\u4f86\u7814\u7a76\u5404\u7a2e\u75c5\u6bd2\u3001\u7d30\u83cc\u7684DNA\uff0c\u4ee5\u53ca\u771f\u6838\u7d30\u80de\u4e2d\u67d3\u8272\u9ad4\u7684\u7d50\u69cb\u3002\u5230\u4e86\u535a\u58eb\u5f8c\u7814\u7a76\u671f\u9593\uff0c\u6c88\u8001\u5e2b\u63a5\u89f8\u4e86DNA\u514b\u9686\u7684\u6280\u8853\uff0c\u4e5f\u521d\u6b21\u9032\u884c\u8868\u89c0\u907a\u50b3\u7684DNA\u7532\u57fa\u5316\u7814\u7a76\u30021981\u5e74\u6642\uff0c\u6c88\u8001\u5e2b\u5230\u52a0\u5dde\u5927\u5b78\u6234\u7dad\u65af\u5206\u6821\u907a\u50b3\u5b78\u7cfb\u4efb\u8077\u3002\u61b6\u8d77\u7576\u6642\uff0c\u56e0\u70ba\u9700\u8981\u6559\u6388\u907a\u50b3\u5b78\u7684\u7de3\u6545\uff0c\u8001\u5e2b\u5728\u90a3\u88e1\u5b78\u5230\u4e86\u5f88\u591a\u4eba\u985e\u907a\u50b3\u5b78\u3001\u65cf\u7fa4\u907a\u50b3\u5b78\u7b49\u77e5\u8b58\uff0c\u5c0d\u5f8c\u4f86\u505a\u5be6\u9a57\u3001\u601d\u8003\u90fd\u5f88\u6709\u5e6b\u52a9\u30021994\u5e74\u56de\u5230\u4e86\u53f0\u7063\u4e2d\u7814\u9662\u5206\u5b50\u751f\u7269\u7814\u7a76\u6240\uff0c\u6c88\u8001\u5e2b\u6839\u64da\u9577\u4e45\u4ee5\u4f86\u5c0d\u795e\u7d93\u6f14\u5316\u7684\u8208\u8da3\u800c\u9032\u5165\u4e86\u5206\u5b50\u7d30\u80de\u795e\u7d93\u5b78\u7684\u7814\u7a76\uff0c\u70ba\u5f4c\u88dc\u4e0d\u8db3\u7684\u80cc\u666f\u77e5\u8b58\u52aa\u529b\u5b78\u7fd2\u8457\u3002\u53e6\u5916\uff0c\u56e0\u70ba\u904e\u53bb\u505a\u904eDNA\u7532\u57fa\u5316\u7684\u7814\u7a76\uff0c\u4e14\u8868\u89c0\u907a\u50b3\u5728\u8fd1\u5341\u5e74\u3001\u5341\u4e94\u5e74\u958b\u59cb\u8b8a\u5f97\u975e\u5e38\u91cd\u8981\uff0c\u6c88\u8001\u5e2b\u76ee\u524d\u7684\u5be6\u9a57\u5ba4\u4e5f\u540c\u6642\u5728\u9032\u884c\u6709\u95dc\u8868\u89c0\u907a\u50b3\u7684\u7814\u7a76\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u898b\u8b49\u53f0\u7063\u5206\u5b50\u751f\u7269\u5b78\u7684\u767c\u5c55<\/strong><\/span><\/p>\n<p>1993\u5e74\u4e2d\u7814\u9662\u5206\u5b50\u751f\u7269\u7814\u7a76\u6240\u6b63\u5f0f\u6210\u7acb\uff0c\u5169\u5e74\u5f8c\u6c88\u8001\u5e2b\u88ab\u9080\u8acb\u56de\u53f0\u64d4\u4efb\u6240\u9577\uff0c\u4e00\u7576\u5c31\u662f\u4e5d\u5e74\u3002\u8ac7\u8d77\u904e\u53bb\u53f0\u7063\u5206\u5b50\u751f\u7269\u5b78\u7684\u767c\u5c55\uff0c\u8001\u5e2b\u8aaa\u65e9\u57281982\u5e74\u6642\uff0c\u53f0\u7063\u5c31\u5df2\u958b\u59cb\u5f15\u9032\u5206\u5b50\u751f\u7269\u5b78\u7684\u89c0\u5ff5\uff0c\u958b\u8fa6\u4e86\u8a31\u591a\u5de5\u4f5c\u574a\u3001\u76f8\u95dc\u6f14\u8b1b\u7b49\uff0c\u4f46\u5be6\u9a57\u65b9\u9762\uff0c\u56e0\u70ba\u85e5\u54c1\u9700\u8981\u5f9e\u7f8e\u570b\u9032\u53e3\u5f88\u4e0d\u65b9\u4fbf\uff0c\u5206\u5b50\u751f\u7269\u5b78\u7684\u8ab2\u7a0b\u4e5f\u8f03\u5c11\uff0c\u5230\u4e861988\u5e74\u5f8c\u7814\u7a76\u624d\u958b\u59cb\u6f38\u5165\u4f73\u5883\u3002\u6c88\u8001\u5e2b\u57281994\u5e74\u5e95\u56de\u53f0\u6642\uff0c\u53f0\u7063\u7684\u5206\u5b50\u751f\u7269\u5b78\u5df2\u7d93\u505a\u5f97\u5f88\u597d\uff0c\u5230\u73fe\u5728\u53f0\u7063\u5728\u9019\u500b\u9818\u57df\u767c\u5c55\u7684\u76f8\u7576\u4e0d\u932f\uff0c\u5728\u5be6\u9a57\u6280\u5de7\u3001\u601d\u7dad\u524d\u77bb\u6027\u7b49\uff0c\u53f0\u7063\u8001\u5e2b\u505a\u7684\u7814\u7a76\uff0c\u90fd\u6709\u4e00\u5b9a\u7684\u6c34\u6e96\u53ef\u4ee5\u8ddf\u570b\u5916\u7af6\u722d\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u8868\u89c0\u907a\u50b3\u8207DNA\u5e8f\u5217\u7684\u5171\u821e<\/strong><\/span><\/p>\n<p>\u8ac7\u8d77\u8868\u89c0\u907a\u50b3\u8207DNA\u5e8f\u5217\u9593\u7684\u95dc\u4fc2\uff0c\u6c88\u8001\u5e2b\u6ed4\u6ed4\u4e0d\u7d55\u5730\u5206\u4eab\u5169\u8005\u4f5c\u7528\u7684\u5967\u5999\u4e4b\u8655\u3002DNA\u5e8f\u5217\u6539\u8b8a\u56fa\u7136\u6703\u5f71\u97ff\u57fa\u56e0\u7684\u8868\u73fe\uff0c\u4f8b\u5982\u8a31\u591a\u764c\u75c7\u7d30\u80de\u5728DNA\u5e8f\u5217\u7686\u6709\u6240\u6539\u8b8a\uff0c\u9020\u6210\u86cb\u767d\u8cea\u4e0d\u7522\u751f\u6216\u8868\u73fe\u8cea\u91cf\u6709\u6240\u5dee\u7570\uff1b\u7136\u800c\u53e6\u4e00\u65b9\u9762\uff0c\u4e5f\u6709\u4e00\u4e9b\u5e8f\u5217\u6539\u8b8a\u5f8c\uff0c\u6539\u8b8a\u7684\u86cb\u767d\u4e26\u4e0d\u6703\u76f4\u63a5\u81f4\u764c\uff0c\u800c\u662f\u5f71\u97ffDNA\u67d3\u8272\u9ad4\u7684\u4fee\u98fe\uff0c\u9020\u6210\u6574\u500b\u7d30\u80de\u4e2d\u591a\u500b\u57fa\u56e0\u7684\u8868\u73fe\u8cea\u91cf\u56e0\u800c\u6539\u8b8a\uff0c\u9593\u63a5\u7684\u5f15\u767c\u4e86\u764c\u75c7\u3002\u7531\u4ee5\u4e0a\u4f8b\u5b50\uff0c\u6211\u5011\u53ef\u770b\u5230\u8868\u89c0\u907a\u50b3\u5728DNA\u5e8f\u5217\u5c64\u6b21\u4e4b\u4e0a\uff0c\u53e6\u5916\u4e00\u5c64\u7684\u8abf\u63a7\u4e5f\u662f\u975e\u5e38\u91cd\u8981\u7684\u3002\u8868\u89c0\u907a\u50b3\u5305\u62ec\u4e86\u7d44\u86cb\u767d\u7684\u4fee\u98fe\u3001DNA\u7532\u57fa\u5316\u7b49\uff0c\u800c\u57fa\u56e0\u9ad4DNA\u7684\u67d0\u4e9b\u90e8\u4efd\u4e00\u7d93\u4fee\u98fe\uff0c\u6703\u6539\u8b8a\u597d\u5e7e\u500b\u57fa\u56e0\u7684\u8868\u73fe\u3002\u6c88\u8001\u5e2b\u4e5f\u6307\u51fa\uff0c\u73fe\u4eca\u5f88\u591a\u75be\u75c5\u90fd\u88ab\u767c\u73fe\u8207\u8868\u89c0\u907a\u50b3\u6709\u95dc\uff0c\u4f8b\u5982\u81ea\u9589\u75c7(autism)\u3001\u7cbe\u795e\u5206\u88c2\u75c7 (Schizophrenia)\u3001\u5931\u667a\u75c7 (Dementia) \u7b49\uff0c\u5728\u8868\u89c0\u907a\u50b3\u4e0a\u90fd\u6709\u6240\u6539\u8b8a\uff1b\u76ee\u524d\u4e5f\u6709\u5f88\u591a\u4ee5\u8868\u89c0\u907a\u50b3\u7232\u6a19\u7684\u85e5\u7269\uff0c\u6b63\u5728\u9032\u884c\u7814\u767c\u3002<\/p>\n<p><span style=\"color: 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