{"id":29626,"date":"2017-12-22T00:50:39","date_gmt":"2017-12-21T16:50:39","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=29626"},"modified":"2018-07-29T13:27:28","modified_gmt":"2018-07-29T05:27:28","slug":"%e8%87%aa%e9%96%89%e7%97%87%ef%bc%8c%e6%9c%83%e4%b8%8d%e6%9c%83%e6%98%af%e6%89%93%e5%be%9e%e5%a8%98%e8%83%8e%e4%be%86%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=29626","title":{"rendered":"\u81ea\u9589\u7684\u4e16\u754c\u4e26\u4e0d\u81ea\u9589\uff1f\u8178\u9053\u83cc\u53e2\u6709\u809a\u88e1\u86d4\u87f2\u8a71\u8981\u8aaa"},"content":{"rendered":"<p><span style=\"color: #333399;\"><strong>\u25a0\u61f7\u5b55\u671f\u9593\u5982\u679c\u53d7\u5230\u75c5\u6bd2\u6216\u662f\u7d30\u83cc\u611f\u67d3\uff0c\u6703\u4e0d\u6703\u5f71\u97ff\u5230\u80ce\u5152\u7684\u795e\u7d93\u767c\u80b2\u3001\u8207\u51fa\u751f\u5f8c\u7684\u884c\u70ba\u767c\u5c55\u5462\uff1f\u4e4b\u524d\u8332\u5361\u75c5\u6bd2\u5c0e\u81f4\u5c0f\u8166\u75c7\u7684\u6182\u616e\uff0c\u9020\u6210\u4eba\u5fc3\u60f6\u60f6\u3002\u4f46\u5176\u5be6\u65e9\u5728\u8332\u5361\u75c5\u6bd2\u75ab\u60c5\u51fa\u73fe\u4e4b\u524d\uff0c\u5c31\u6709\u4e0d\u5c11\u7814\u7a76\u767c\u73fe\uff0c\u61f7\u5b55\u671f\u7684\u75c5\u6bd2\u8207\u7d30\u83cc\u611f\u67d3\uff0c\u6709\u53ef\u80fd\u589e\u52a0\u80ce\u5152\u65e5\u5f8c\u5f97\u5230\u601d\u89ba\u5931\u8abf\u75c7\u8207\u81ea\u9589\u75c7\u7684\u98a8\u96aa\u3002\u9019\u662f\u70ba\u4ec0\u9ebc\u5462\uff1f<\/strong><\/span><\/p>\n<p><strong><img fetchpriority=\"high\" decoding=\"async\" class=\"alignleft wp-image-29635\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/09\/pic.jpg\" alt=\"\" width=\"450\" height=\"312\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/09\/pic.jpg 980w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/09\/pic-600x416.jpg 600w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/09\/pic-800x555.jpg 800w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/>\u64b0\u6587\uff5c<\/strong>\u99f1\u5b9b\u7433<\/p>\n<p>\u61f7\u5b55\u7684\u6642\u5019\uff0c\u5982\u679c\u88ab\u75c5\u6bd2\u6216\u7d30\u83cc\u611f\u67d3\uff0c\u6709\u53ef\u80fd\u589e\u52a0\u80ce\u5152\u795e\u7d93\u767c\u80b2\u969c\u7919\u7684\u5371\u96aa\u3002\u76ee\u524d\u7684\u7814\u7a76\uff0c\u591a\u534a\u628a\u77db\u982d\u6307\u5411\u601d\u89ba\u5931\u8abf\u75c7\u8207\u81ea\u9589\u75c7\u30022010 \u5e74\u6642\u6709\u6d41\u884c\u75c5\u5b78\u7814\u7a76\u6307\u51fa\uff0c\u5982\u679c\u5b55\u671f\u6642\uff0c\u80fd\u5920\u9810\u9632\u5b55\u5a66\u88ab\u75c5\u6bd2\u3001\u7d30\u83cc\u8207\u5bc4\u751f\u87f2\u611f\u67d3\u7684\u8a71\uff0c\u6216\u8a31\u601d\u89ba\u5931\u8abf\u75c7\u7684\u6848\u4f8b\u80fd\u4e0b\u964d\u4e09\u6210\u3002\u800c\u8b93\u81e8\u5e8a\u7814\u7a76\u5c08\u5bb6\u76ba\u7709\u7684\u5acc\u7591\u72af\uff0c\u5305\u62ec\u4e86\u6d41\u611f\u75c5\u6bd2\u3001\u55ae\u7d14\u76b0\u75b9\u75c5\u6bd2\u3001\u5fb7\u570b\u9ebb\u75b9\uff0c\u9084\u6709\u7d30\u83cc\u611f\u67d3\uff0c\u8207\u5bc4\u751f\u87f2\u5f13\u87f2\u75c7\u611f\u67d3\u3002\u7dca\u63a5\u8457\u4e0d\u4e45\uff0c\u4ee5\u4e39\u9ea5\u4e00\u842c\u4ef6\u81ea\u9589\u75c7\u6848\u4f8b\u70ba\u4e3b\u7684\u7814\u7a76\uff0c\u4e5f\u767c\u73fe\u81ea\u9589\u75c7\u7f79\u60a3\u7387\u8ddf\u7b2c\u4e00\u5b55\u671f\u9593\u7684\u75c5\u6bd2\u611f\u67d3\u6709\u6975\u70ba\u986f\u8457\u95dc\u806f\u3002<!--more--><\/p>\n<p>\u9019\u4e9b\u6578\u64da\u807d\u8d77\u4f86\u50cf\u662f\u6050\u6016\u7684\u90fd\u5e02\u50b3\u8aaa\uff0c\u4f46\u5728\u8001\u9f20\u8eab\u4e0a\uff0c\u985e\u4f3c\u7684\u95dc\u806f\u4e5f\u5df2\u5728\u5be6\u9a57\u6a21\u578b\u88e1\u88ab\u9a57\u8b49\u3002\u61f7\u5b55\u671f\u9593\uff0c\u5982\u679c\u6bcd\u9ad4\u514d\u75ab\u7cfb\u7d71\u6d3b\u5316\uff08maternal immune activation\uff09\uff0c\u53ef\u80fd\u6703\u5f71\u97ff\u5230\u5b50\u4ee3\u7684\u795e\u7d93\u767c\u80b2\u8207\u884c\u70ba\u6a21\u5f0f\u3002\u5728\u5c0f\u8001\u9f20\u8eab\u4e0a\uff0c\u5982\u679c\u6bcd\u9f20\u61f7\u5b55\u671f\u9593\u88ab\u6d41\u611f\u75c5\u6bd2\u611f\u67d3\uff0c\u6216\u662f\u5229\u7528\u5408\u6210\u7684\u96d9\u80a1 RNA \u591a\u805a\u808c\u82f7\u9178\u591a\u805a\u80de\u82f7\u9178 poly (I:C) \u4f86\u6a21\u64ec\u75c5\u6bd2\u611f\u67d3\uff0c\u53c8\u6216\u8005\u5229\u7528\u7d30\u83cc\u5916\u6a21\u7d50\u69cb\u4e0a\u7684\u8102\u591a\u91a3\u5f15\u8d77\u61f7\u5b55\u6bcd\u9f20\u9ad4\u5167\u7684\u767c\u708e\u53cd\u61c9\uff0c\u5b50\u4ee3\u5c0f\u9f20\u5c31\u5f88\u5bb9\u6613\u51fa\u73fe\u5178\u578b\u81ea\u9589\u75c7\u75c7\u72c0\uff1a\u50cf\u662f\u793e\u4ea4\u969c\u7919\u3001\u9ad8\u5ea6\u7126\u616e\uff0c\u8207\u91cd\u8907\u504f\u57f7\u7684\u884c\u70ba\u6a21\u5f0f\uff0c\u6703\u50cf\u8457\u9b54\u4f3c\u5730\u4e0d\u65b7\u628a\u5f48\u73e0\u57cb\u8d77\u4f86\u3002<\/p>\n<p>\u6700\u8fd1\u5728\u00a0<em>Nature\u00a0<\/em>\u671f\u520a\u4e0a\uff0c\u7f8e\u570b\u9ebb\u5dde\u5927\u5b78\u91ab\u5b78\u9662\u7684 Jun Huh \u535a\u58eb\uff0c\u548c\u9ebb\u7701\u7406\u5de5\u5b78\u9662\u7684 Gloria Choi \u535a\u58eb\u767c\u8868\u4e86\u5169\u7bc7\u7814\u7a76\u3002\u5169\u500b\u5be6\u9a57\u5ba4\u5408\u529b\u63d0\u51fa\u4e86\u53ef\u80fd\u7684\u80cc\u5f8c\u6a5f\u8f49\uff0c\u70ba\u6bcd\u9ad4\u514d\u75ab\u53cd\u61c9\u6d3b\u5316\uff0c\u8207\u5b50\u4ee3\u795e\u7d93\u884c\u70ba\u6a21\u5f0f\u4e4b\u9593\u7684\u95dc\u806f\u6027\uff0c\u63d0\u51fa\u5f37\u800c\u6709\u529b\u7684\u80cc\u66f8\u3002\u4ed6\u5011\u4e00\u500b\u5be6\u9a57\u5ba4\u4ee5\u514d\u75ab\u5b78\u7684\u89d2\u5ea6\u5207\u5165\u6bcd\u9f20\u61f7\u5b55\u671f\u9593\uff0c\u6bcd\u9ad4\u514d\u75ab\u6d3b\u5316\u5c0d\u5e7c\u9f20\u884c\u70ba\u6a21\u5f0f\u7684\u5f71\u97ff\uff1b\u53e6\u4e00\u500b\u5be6\u9a57\u5ba4\u628a\u7814\u7a76\u7126\u9ede\u653e\u5728\u6bcd\u9ad4\u514d\u75ab\u6d3b\u5316\u5c0d\u5e7c\u9f20\u5927\u8166\u795e\u7d93\u767c\u80b2\u7684\u5f71\u97ff\uff0c\u5169\u7bc7\u7814\u7a76\u4e92\u76f8\u652f\u6301\u4e5f\u5de7\u5999\u4e92\u88dc\u5730\u8b93\u5b55\u671f\u611f\u67d3\u8207\u80ce\u5152\u884c\u70ba\u4e4b\u9593\u7684\u56e0\u679c\u95dc\u4fc2\uff0c\u6709\u4e86\u5408\u5b9c\u7684\u89e3\u91cb\u3002<\/p>\n<p>\u7f8e\u570b\u9ebb\u5dde\u5927\u5b78\u91ab\u5b78\u9662\u7684 Jun Huh \u535a\u58eb\u5be6\u9a57\u5ba4\uff0c\u5229\u7528 poly (I:C) \u6a21\u64ec\u75c5\u6bd2\u611f\u67d3\uff0c\u767c\u73fe\u5982\u679c\u8a98\u767c\u61f7\u5b55\u6bcd\u9f20\u9ad4\u5167\u7684\u514d\u75ab\u7cfb\u7d71\u6d3b\u5316\uff0c\u61f7\u5b55\u6bcd\u9f20\u8840\u6db2\u5167\u7684\u7d30\u80de\u6fc0\u7d20 IL-17 \u6fc3\u5ea6\u6703\u7570\u5e38\u589e\u9ad8\uff0c\u5c0f\u8178\u5167\u7684\u8f14\u52a9\u578b Th17 \u7d30\u80de\u4e5f\u7570\u5e38\u589e\u751f\uff0c\u7136\u5f8c\u751f\u51fa\u4f86\u7684\u5c0f\u8001\u9f20\u4e5f\u90fd\u51fa\u73fe\u81ea\u9589\u75c7\u884c\u70ba\u3002\u4f46\u6709\u8da3\u7684\u662f\uff0c\u5982\u679c\u5728\u7d66\u4e88\u61f7\u5b55\u6bcd\u9f20 poly (I:C) \u4e4b\u5f8c\uff0c\u4e5f\u53ca\u6642\u7d66\u4e88\u6297\u751f\u7d20\u842c\u53e4\u9ef4\u7d20\u6cbb\u7642\uff0c\u5b50\u4ee3\u5c0f\u9f20\u985e\u4f3c\u81ea\u9589\u75c7\u5f0f\u7684\u884c\u70ba\uff0c\u5c31\u53ef\u4ee5\u6709\u6548\u9810\u9632\u4e86\u3002\u53ef\u898b\u61f7\u5b55\u6bcd\u9f20\u9ad4\u5167\u7684\u8178\u9053\u83cc\u53e2\uff0c\u548c\u5b50\u4ee3\u5c0f\u9f20\u51fa\u73fe\u985e\u4f3c\u81ea\u9589\u75c7\u7684\u884c\u70ba\uff0c\u6709\u8457\u76f4\u63a5\u95dc\u806f\u3002\u90a3\u7f6a\u9b41\u798d\u9996\u662f\u8ab0\uff1f\u900f\u904e\u986f\u5fae\u93e1\u89c0\u5bdf\u8207\u8178\u9053\u83cc\u53e2 DNA \u5206\u6790\uff0c\u7814\u7a76\u4eba\u54e1\u767c\u73fe\u6bcd\u9f20\u8178\u9053\u5167\u7684\u5206\u7bc0\u7d72\u72c0\u83cc\uff08segmented filamentous bacteria\uff09\u662f\u6700\u6709\u53ef\u80fd\u7684\u982d\u865f\u5acc\u7591\u72af\u3002<\/p>\n<p>\u70ba\u4e86\u8981\u8b93\u5206\u7bc0\u7d72\u72c0\u83cc\u7684\u7f6a\u884c\u7f6a\u8b49\u78ba\u947f\uff0cHuh \u535a\u58eb\u5be6\u9a57\u5ba4\u505a\u4e86\u4e00\u4ef6\u5f88\u6709\u8da3\u7684\u4e8b\u3002\u4ed6\u5011\u5f9e\u5169\u500b\u4e0d\u540c\u7684\u8001\u9f20\u5be6\u9a57\u4e2d\u5fc3 Jackson Lab\uff08Jax\uff09\u548c Taconic Biosciences\uff08Tac\uff09\u8cb7\u4f86\u540c\u54c1\u7cfb\u7684\u8001\u9f20\u3002\u4f46\u56e0\u70ba\u6bcf\u500b\u6a5f\u69cb\u7684\u74b0\u5883\u83cc\u53e2\u90fd\u4e0d\u592a\u4e00\u6a23\uff0c\u525b\u597d\u5f9e Tac \u6a5f\u69cb\u8cb7\u4f86\u7684\u7d14\u54c1\u7cfb\u5c0f\u9f20\u5e36\u6709\u5206\u7bc0\u7d72\u72c0\u83cc\uff0c\u800c\u5f9e Jax \u5be6\u9a57\u4e2d\u5fc3\u8cb7\u4f86\u7684\u6c92\u6709\u3002\u7576\u540c\u6642\u8b93\u5169\u500b\u4e0d\u540c\u4f86\u6e90\u7684\u61f7\u5b55\u6bcd\u9f20\u90fd\u88ab\u6ce8\u5c04 poly (I:C) \u6d3b\u5316\u61f7\u5b55\u6bcd\u9f20\u9ad4\u5167\u514d\u75ab\u53cd\u61c9\uff0c\u5f9e Jax \u5be6\u9a57\u4e2d\u5fc3\u4f86\u7684\u6bcd\u9f20\u751f\u4e0b\u4f86\u7684\u5c0f\u8001\u9f20\u5b8c\u5168\u6c92\u4e8b\uff0c\u4f46\u5f9e Tac \u4f86\u7684\u6bcd\u9f20\uff0c\u751f\u4e0b\u4f86\u7684\u5b50\u4ee3\u5e7c\u9f20\u537b\u548c\u4e4b\u524d\u7684\u52d5\u7269\u5be6\u9a57\u6a21\u578b\u4e00\u6a23\uff0c\u51fa\u73fe\u985e\u4f3c\u81ea\u9589\u75c7\u7684\u75c7\u72c0\u3002\u4f46\u5982\u679c\u5c07\u5206\u7bc0\u7d72\u72c0\u83cc\u704c\u6ce8\u5165 Jax \u5be6\u9a57\u4e2d\u5fc3\u4f86\u7684\u61f7\u5b55\u6bcd\u9f20\uff0c\u5247\u5b50\u4ee3\u5c0f\u9f20\u7684\u884c\u70ba\u6a21\u5f0f\u4e5f\u6703\u51fa\u73fe\u7126\u616e\u3001\u91cd\u8907\u884c\u70ba\uff0c\u4e26\u4e14\u9003\u907f\u793e\u4ea4\u523a\u6fc0\u3002<\/p>\n<p>\u9019\u500b\u5be6\u9a57\u4e0d\u50c5\u843d\u5be6\u8178\u9053\u83cc\u53e2\u5728\u6bcd\u9ad4\u514d\u75ab\u53cd\u61c9\u6d3b\u5316\u4e2d\u6240\u626e\u6f14\u7684\u95dc\u9375\u89d2\u8272\uff0c\u4e5f\u9ede\u51fa\u4e00\u4ef6\u6709\u8da3\u7684\u7d30\u7bc0\u3002\u56e0\u70ba\u5728\u5206\u7bc0\u7d72\u72c0\u83cc\u6240\u8a98\u767c\u7684\u6bcd\u9ad4\u514d\u75ab\u6d3b\u5316\u53cd\u61c9\u4e2d\uff0c\u589e\u751f\u7684\u8f14\u52a9\u578b Th17 \u7d30\u80de\u80fd\u5920\u7acb\u5373\u91dd\u5c0d\u7d30\u83cc\u611f\u67d3\u53cd\u61c9\uff0c\u4ee3\u8868\u9019\u7fa4\u7d30\u80de\u662f\u672c\u4f86\u5c31\u5b58\u5728\u65bc\u61f7\u5b55\u6bcd\u9f20\u9ad4\u5167\u3002\u56e0\u70ba\uff0c\u5982\u679c\u662f\u7b2c\u4e00\u6b21\u514d\u75ab\u53cd\u61c9\uff0c\u901a\u5e38\u9700\u8981\u5e7e\u5929\u7684\u6642\u9593\uff0c\u624d\u80fd\u5920\u5c07\u514d\u75ab\u53cd\u61c9\u597d\u597d\u6d3b\u5316\u3002<\/p>\n<p>\u90a3\u6bcd\u9ad4\u514d\u75ab\u53cd\u61c9\u53c8\u5f71\u97ff\u5230\u4e86\u5b50\u4ee3\u5c0f\u9f20\u5927\u8166\u4e2d\u7684\u54ea\u4e00\u500b\u53cd\u61c9\u5340\u584a\u5462\uff1f\u9ebb\u7701\u7406\u5de5\u5b78\u9662\u7684 Gloria Choi \u535a\u58eb\u5be6\u9a57\u5ba4\u7531\u6b64\u63a5\u624b\uff0c\u5229\u7528\u5149\u907a\u50b3\u5b78\uff08optogenetics\uff09\u7684\u6280\u8853\uff0c\u7814\u7a76\u6bcd\u9ad4\u514d\u75ab\u53cd\u61c9\u662f\u5982\u4f55\u5f71\u97ff\u5b50\u4ee3\u5e7c\u9f20\u7684\u5927\u8166\u767c\u80b2\uff0c\u9032\u800c\u6539\u8b8a\u884c\u70ba\u6a21\u5f0f\u3002\u6240\u8b02\u7684\u5149\u907a\u50b3\u5b78\uff0c\u662f\u5229\u7528\u57fa\u56e0\u5de5\u7a0b\u6280\u8853\uff0c\u5c07\u5c0d\u7279\u5b9a\u6ce2\u9577\u7684\u5149\u6709\u53cd\u61c9\u7684\u96e2\u5b50\u901a\u9053\u8868\u73fe\u5728\u5927\u8166\u7279\u5730\u5340\u584a\u3002\u9019\u4e9b\u5c0d\u5149\u654f\u611f\u7684\u96e2\u5b50\u901a\u9053\uff0c\u5728\u63a5\u53d7\u5230\u7279\u5b9a\u6ce2\u9577\u7684\u5149\u7dda\u4e4b\u5f8c\uff0c\u6703\u88ab\u6d3b\u5316\u3002\u56e0\u6b64\uff0c\u85c9\u7531\u8abf\u63a7\u5c0d\u5149\u654f\u611f\u7684\u96e2\u5b50\u901a\u9053\u8868\u73fe\u5728\u5927\u8166\u54ea\u4e00\u500b\u5340\u57df\uff0c\u5c31\u53ef\u4ee5\u9032\u800c\u6d3b\u5316\u3001\u6216\u662f\u6291\u5236\u8a72\u5340\u7684\u795e\u7d93\u6d3b\u6027\u3002\u800c\u85c9\u7531\u5149\u907a\u50b3\u5b78\u6280\u8853\uff0cChoi \u535a\u58eb\u5be6\u9a57\u5ba4\u767c\u73fe\uff0c\u5728\u5927\u8166\u4e3b\u8981\u9ad4\u89ba\u76ae\u8cea\u90e8\u4f4d\uff08primary somatosensory cortex\uff09 \u7684\u7570\u9846\u7c92\u5340\uff08dysgranular zone\uff09\u795e\u7d93\u5143\uff0c\u662f\u4e3b\u8981\u9020\u6210\u5c0f\u9f20\u51fa\u73fe\u985e\u4f3c\u81ea\u9589\u75c7\u884c\u70ba\u7684\u6e90\u982d\u3002\u85c9\u7531\u63a7\u5236\u9019\u5340\u57df\u795e\u7d93\u5143\u7684\u6d3b\u6027\uff0c\u5c31\u6703\u5f71\u97ff\u5230\u5c0f\u9f20\u662f\u4e0d\u662f\u6703\u51fa\u73fe\u793e\u4ea4\u969c\u7919\u8207\u91cd\u8907\u504f\u57f7\u7684\u884c\u70ba\u3002<\/p>\n<p>Jun Huh \u535a\u58eb\u5be6\u9a57\u5ba4\u548c Gloria Choi \u535a\u58eb\u5be6\u9a57\u5ba4\u806f\u624b\u767c\u8868\u7684\u5169\u7bc7\u7814\u7a76\uff0c\u7b97\u662f\u70ba\u61f7\u5b55\u6642\u671f\u6bcd\u9ad4\u514d\u75ab\u53cd\u61c9\u6d3b\u5316\uff0c\u8207\u5b50\u4ee3\u795e\u7d93\u767c\u80b2\u8207\u884c\u70ba\u6a21\u5f0f\u4e4b\u9593\u7684\u95dc\u806f\u6027\uff0c\u6709\u4e86\u4e00\u500b\u597d\u89e3\u91cb\u3002\u4e4b\u5f8c\uff0c\u4ed6\u5011\u5728\u5be6\u9a57\u5c0f\u9f20\u8eab\u4e0a\u6240\u5b78\u5230\u7684\u4e8b\uff0c\u662f\u4e0d\u662f\u4e5f\u80fd\u62ff\u4f86\u89e3\u91cb\u6d41\u884c\u75c5\u5b78\u7814\u7a76\u6240\u89c0\u5bdf\u5230\u7684\u95dc\u806f\u6027\uff0c\u9084\u503c\u5f97\u62ed\u76ee\u4ee5\u5f85\u3002<\/p>\n<p><strong>\u539f\u59cb\u8ad6\u6587\uff1a<\/strong><\/p>\n<ol>\n<li>Shin Yim Y, et al. Reversing behavioural abnormalities in mice exposed to maternal inflammation. Nature. 2017 Sep 13. doi: 10.1038\/nature23909.<\/li>\n<li>Kim S et al. Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring. Nature. 2017 Sep 13. doi: 10.1038\/nature23910.<\/li>\n<\/ol>\n<p><strong>--<\/strong><br \/>\n<span style=\"color: #333399;\"><strong>\u4f5c\u8005\uff1a\u99f1\u5b9b\u7433\u3000\u7f8e\u570b\u8056\u8def\u6613\u83ef\u76db\u9813\u5927\u5b78\uff08Washington University in St. Louis\uff09\u514d\u75ab\u5b78\u535a\u58eb\uff0c\u5f9e\u4e8bT\u7d30\u80de\u767c\u80b2\u8207\u6d3b\u5316\u76f8\u95dc\u7684\u8a0a\u606f\u50b3\u5c0e\u7814\u7a76\u3002<\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0\u61f7\u5b55\u671f\u9593\u5982\u679c\u53d7\u5230\u75c5\u6bd2\u6216\u662f\u7d30\u83cc\u611f\u67d3\uff0c\u6703\u4e0d\u6703\u5f71\u97ff\u5230\u80ce\u5152\u7684\u795e\u7d93\u767c\u80b2\u3001\u8207\u51fa\u751f\u5f8c\u7684\u884c\u70ba\u767c\u5c55\u5462\uff1f\u4e4b\u524d\u8332\u5361\u75c5\u6bd2\u5c0e\u81f4\u5c0f\u8166\u75c7\u7684\u6182\u616e\uff0c\u9020\u6210\u4eba\u5fc3\u60f6\u60f6\u3002\u4f46\u5176\u5be6\u65e9\u5728\u8332\u5361\u75c5\u6bd2\u75ab\u60c5\u51fa\u73fe\u4e4b\u524d\uff0c\u5c31\u6709\u4e0d\u5c11\u7814\u7a76\u767c\u73fe\uff0c\u61f7\u5b55\u671f\u7684\u75c5\u6bd2\u8207\u7d30\u83cc\u611f\u67d3\uff0c\u6709\u53ef\u80fd\u589e\u52a0\u80ce\u5152\u65e5\u5f8c\u5f97\u5230\u601d\u89ba\u5931\u8abf\u75c7\u8207\u81ea\u9589\u75c7\u7684\u98a8\u96aa\u3002\u9019\u662f\u70ba\u4ec0\u9ebc\u5462\uff1f<\/p>\n","protected":false},"author":20,"featured_media":29635,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,1025],"tags":[1807,399,1339,384],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/09\/pic.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/29626"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=29626"}],"version-history":[{"count":4,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/29626\/revisions"}],"predecessor-version":[{"id":31907,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/29626\/revisions\/31907"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/29635"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=29626"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=29626"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=29626"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}