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\u66f4\u6709\u8da3\u7684\u662f\uff0c\u5982\u679c\u56de\u9867\u6b77\u53f2\uff0c\u767c\u708e\u53cd\u61c9\u548c\u7cbe\u795e\u5931\u8abf\u75be\u75c5\u624b\u628a\u624b\u7684\u88d9\u5e36\u95dc\u4fc2\u4e00\u76f4\u5728\u81e8\u5e8a\u4e0a\u70ba\u4eba\u8b66\u89ba\u3002Wagner-Jauregg\u00a0 \u91ab\u751f\u9084\u70ba\u6b64\u5f97\u5230\u8afe\u8c9d\u723e\u734e\u7684\u6b8a\u69ae\u5462\uff011883\u5e74\u7684\u6642\u5019\uff0cWagner-Jauregg \u525b\u597d\u78b0\u5230\u4e00\u500b\u6709\u7cbe\u795e\u5984\u60f3\u75c7\u60a3\u8005\uff0c\u9019\u540d\u60a3\u8005\u5728\u56e0\u70ba\u76ae\u819a\u611f\u67d3\u800c\u767c\u4e86\u4e00\u5834\u9ad8\u71d2\u4e4b\u5f8c\uff0c\u96a8\u8457\u71d2\u9000\uff0c\u601d\u89ba\u5931\u8abf\u75c7\u4e5f\u795e\u5947\u5730\u4e00\u4f75\u75ca\u7652\u4e86\uff01Wagner-Jauregg \u5f8c\u4f86\u5728 1917 \u5e74\u6642\u7814\u767c\u51fa\u7576\u6642\u7a31\u4f5c\u300c\u7627\u75be\u7642\u6cd5\u300d\u7684\u4ee5\u6bd2\u653b\u6bd2\u6cbb\u7642\u7b56\u7565\uff0c\u5c0d\u6885\u6bd2\u611f\u67d3\u665a\u671f\u3001\u51fa\u73fe\u601d\u89ba\u5931\u8abf\u75c7\u72c0\u6216\u7cbe\u795e\u5931\u5e38\u7684\u60a3\u8005\uff0c\u6ce8\u5c04\u611f\u67d3\u4e86\u7627\u75be\u7684\u58eb\u5175\u8840\u6db2\u3002\u76ee\u7684\u662f\u85c9\u7531\u611f\u67d3\u4e86\u7627\u75be\u7684\u58eb\u5175\u8840\u6db2\u6ce8\u5c04\u5230\u60a3\u8005\u9ad4\u5167\uff0c\u5f15\u8d77\u60a3\u8005\u9ad8\u71d2\uff0c\u7136\u5f8c\u96a8\u8457\u514d\u75ab\u53cd\u61c9\u505c\u6b47\u4e4b\u5f8c\uff0c\u4e4b\u524d\u5931\u8861\u7684\u514d\u75ab\u767c\u708e\u7269\u8cea\u4e5f\u80fd\u5920\u4e00\u4f75\u88ab\u91cd\u65b0\u6b78\u96f6\u3001\u56de\u5230\u6b63\u5e38\u7bc4\u570d\u3002\u64da\u805e\uff0c\u9019\u500b\u300c\u7627\u75be\u7642\u6cd5\u300d\u5728 1920 \u5230 1930 \u671f\u9593\uff0c\u6cbb\u7642\u4e86\u4e0a\u5343\u500b\u75c5\u4eba\uff0cWagner-Jauregg \u91ab\u751f\u66f4\u5728 1927 \u5e74\u7684\u6642\u5019\u70ba\u6b64\u5f97\u5230\u8afe\u8c9d\u723e\u734e\u3002\u5f8c\u4f86\uff0c\u96a8\u8457\u6297\u751f\u7d20\u76e4\u5c3c\u897f\u6797\u7684\u767c\u73fe\uff0c\u5728\u6885\u6bd2\u6cbb\u7642\u4e0a\u7acb\u4e0b\u5927\u529f\uff0c\u9019\u500b\u5728\u73fe\u4eca\u91ab\u7642\u6a19\u6e96\u5f88\u96e3\u5f97\u5bf5\u7684\u300c\u7627\u75be\u7642\u6cd5\u300d\uff0c\u4e5f\u5c31\u96a8\u8457\u88ab\u4eba\u6de1\u5fd8\u800c\u57cb\u5728\u6b77\u53f2\u88e1\u4e86\u3002<\/p>\n

\u81f3\u65bc\u6297\u767c\u708e\u85e5\u662f\u4e0d\u662f\u80fd\u6297\u6182\u9b31\uff0c\u597d\u5e7e\u500b\u81e8\u5e8a\u8a66\u9a57\u90fd\u6b63\u5728\u5982\u706b\u5982\u837c\u7684\u9032\u884c\uff0c\u4e5f\u5e0c\u671b\u7b49\u8a66\u9a57\u7d50\u675f\u7684\u6642\u5019\uff0c\u80fd\u6709\u4ee4\u4eba\u773c\u775b\u4e00\u4eae\u7684\u7d50\u679c\u5462\uff01<\/p>\n

\u53c3\u8003\u8cc7\u6599\uff1a<\/strong><\/p>\n

    \n
  1. Leday GGR, et al. Replicable and Coupled Changes in Innate and Adaptive Immune Gene Expression in Two Case-Control Studies of Blood Microarrays in Major Depressive Disorder. Biol Psychiatry. 2017 Jul 6. pii: S0006-3223(17)31617-7. doi: 10.1016\/j.biopsych.2017.01.021. [Epub ahead of print]<\/li>\n
  2. Kong E, et al. STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behavior. Sci Rep. 2015 Mar 11;5:9009. doi: 10.1038\/srep09009.<\/li>\n
  3. Westsman N. Inflammatory illness: why the next wave of anitodepressants may target the immune system. Nat Med. 2017 Sep 8;23(9):1009-1011. doi: 10.1038\/nm0917-1009.<\/li>\n
  4. Peisajovich A, et al. C-reactive protein at the interface between innate immunity and inflammation. Expert Rev Clin Immunol. 2008 May;4(3):379-90. doi: 10.1586\/1744666X.4.3.379.<\/li>\n<\/ol>\n

    --<\/strong><\/span>
    \n\u4f5c\u8005\uff1a\u99f1\u5b9b\u7433\u3000\u7f8e\u570b\u8056\u8def\u6613\u83ef\u76db\u9813\u5927\u5b78\uff08Washington University in St. Louis\uff09\u514d\u75ab\u5b78\u535a\u58eb\uff0c\u5f9e\u4e8bT\u7d30\u80de\u767c\u80b2\u8207\u6d3b\u5316\u76f8\u95dc\u7684\u8a0a\u606f\u50b3\u5c0e\u7814\u7a76\u3002<\/strong><\/span><\/p>\n

     <\/p>\n

    \"\u52a0\u5165\u597d\u53cb\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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