{"id":29432,"date":"2017-10-06T00:26:36","date_gmt":"2017-10-05T16:26:36","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=29432"},"modified":"2018-07-29T12:22:25","modified_gmt":"2018-07-29T04:22:25","slug":"%e4%b8%80%e6%9c%9d%e8%a2%ab%e8%9f%b2%e5%92%ac%ef%bc%8c%e5%8d%81%e5%b9%b4%e6%80%95%e7%89%9b%e6%8e%92-%e8%ae%93%e4%ba%ba%e5%87%ba%e4%b9%8e%e6%84%8f%e6%96%99%e7%9a%84%e6%8a%97%e7%99%8c","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=29432","title":{"rendered":"\u4e00\u671d\u88ab\u87f2\u54ac\uff0c\u5341\u5e74\u6015\u725b\u6392\u2014\u2014\u8b93\u4eba\u51fa\u4e4e\u610f\u6599\u7684\u6297\u764c\u85e5\u526f\u4f5c\u7528"},"content":{"rendered":"

\"\"\u64b0\u6587\uff5c<\/strong>\u99f1\u5b9b\u7433<\/p>\n

\u300c\u98df\u7269\u904e\u654f\u300d\u662f\u5e38\u898b\u7684\u7169\u60f1\u3002\u6211\u5011\u807d\u904e\u6709\u4eba\u5c0d\u82b1\u751f\u904e\u654f\u3001\u5c0d\u6d77\u9bae\u904e\u654f\u3001\u5c0d\u725b\u5976\u88fd\u54c1\u904e\u654f\u3002\u4f46\u5c0d\u725b\u6392\u904e\u654f\uff1f\u4f3c\u4e4e\u5f88\u96e3\u60f3\u50cf\u3002\u81e8\u5e8a\u4e0a\u7684\u6848\u4f8b\u6709\uff0c\u4f46\u662f\u6975\u70ba\u5c11\u898b\u3002\u7f8e\u570b\u7dad\u5409\u5c3c\u4e9e\u5927\u5b78\u91ab\u5b78\u9662\u7684\u904e\u654f\u79d1\u91ab\u751f Thomas Platts-Mills\uff0c\u56e0\u7de3\u969b\u6703\u5730\u4e00\u982d\u683d\u9032\u4e86\u9019\u500b\u7f55\u898b\u7684\u3001\u300c\u5c0d\u725b\u6392\u904e\u654f\u300d\u7684\u7814\u7a76\u3002\u800c\u9019\u500b\u5f9e\u81e8\u5e8a\u85e5\u7269\u51fa\u73fe\u8b93\u4eba\u6293\u7834\u982d\u60f3\u4e0d\u901a\u7684\u85e5\u7269\u526f\u4f5c\u7528\uff0c\u5230\u5229\u7528\u79d1\u5b78\u57fa\u790e\u7814\u7a76\u800c\u8ffd\u6839\u7a76\u5e95\u3001\u4e00\u63a2\u7a76\u7adf\u7684\u6545\u4e8b\uff0c\u4e5f\u50cf\u6700\u5f8c\u7684\u7814\u7a76\u6210\u679c\u4e00\u6a23\uff0c\u6709\u8da3\u7684\u8b93\u4eba\u773c\u775b\u767c\u4eae\u3002<\/p>\n

Thomas Platts-Mills \u91ab\u751f\u8aaa\uff0c\u4ed6\u6700\u5148\u807d\u5230\u75c5\u4eba\u62b1\u6028\u5c0d\u725b\u8089\u6216\u7d05\u8089\u904e\u654f\uff0c\u5927\u6982\u662f\u4e8c\u5341\u591a\u5e74\u524d\u3002\u6709\u4e00\u5c0f\u7fa4\u75c5\u4eba\u5728\u665a\u9910\u5403\u4e86\u7d05\u8089\u4e4b\u5f8c\uff0c\u534a\u591c\u5728\u7761\u5922\u4e2d\u56e0\u70ba\u904e\u654f\u53cd\u61c9\u9a5a\u5750\u8d77\uff1a\u51b7\u6c57\u76f4\u5192\u3001\u5168\u8eab\u51fa\u73fe\u7d05\u75b9\u3001\u5589\u56a8\u7dca\u3002Platts-Mills \u91ab\u751f\u7576\u6642\u5efa\u8b70\u90a3\u4e9b\u75c5\u4eba\u907f\u514d\u725b\u8089\u3001\u8c6c\u8089\u3001\u7f8a\u8089\uff0c\u4f46\u6697\u5730\u88e1\u89ba\u5f97\u9019\u904e\u654f\u5be6\u5728\u662f\u592a\u7f55\u898b\u4e86\uff0c\u4e5f\u6709\u53ef\u80fd\u662f\u5fc3\u7406\u5f71\u97ff\u751f\u7406\u6240\u9020\u6210\uff0c\u4e26\u6c92\u6709\u60f3\u592a\u591a\u3002<\/p>\n

\u5f8c\u4f86\uff0c\u96a8\u8457\u514d\u75ab\u5b78\u7684\u767c\u5c55\uff0c\u85e5\u7269\u7814\u767c\u4e5f\u9032\u5165\u55ae\u682a\u6297\u9ad4\u85e5\u7269\u84ec\u52c3\u767c\u5c55\u7684\u5e74\u4ee3\u3002\u91cd\u7d44\u55ae\u682a\u6297\u9ad4\uff08recombinant monoclonal antibody\uff09\u88ab\u5ee3\u6cdb\u5229\u7528\u5728\u6cbb\u7642\u764c\u75c7\u3001\u767c\u708e\u6027\u8178\u9053\u75be\u75c5\u3001\u985e\u98a8\u6fd5\u6027\u95dc\u7bc0\u708e\u8207\u6c23\u5598\u75c5\u4eba\u8eab\u4e0a\u3002\u6297\u9ad4\u662f\u514d\u75ab\u7cfb\u7d71B\u7d30\u80de\u6240\u80fd\u88fd\u9020\u7684\u8d85\u5f37\u6b66\u5668\uff0c\u53ef\u4ee5\u5c08\u4e00\u6027\u7684\u8fa8\u8b58\u5165\u4fb5\u75c5\u539f\u83cc\u6216\u5176\u4ed6\u5916\u4f86\u6297\u539f\u3002\u6297\u9ad4\u5982\u679c\u7d50\u5408\u4e0a\u4e86\u5b83\u6240\u80fd\u8fa8\u8b58\u7684\u6297\u539f\uff0c\u6703\u50cf\u7529\u4e5f\u7529\u4e0d\u6389\u7684\u5b9a\u6642\u70b8\u5f48\u4e00\u6a23\uff0c\u8b93\u5916\u4f86\u5165\u4fb5\u8005\u88ab\u6d88\u6ec5\u800c\u8a6d\u8a08\u7121\u6cd5\u5f97\u901e\u3002\u800c\u6bcf\u4e00\u7a2e\u6297\u9ad4\u90fd\u53ea\u6b7b\u5fc3\u584c\u5730\u7684\u8fa8\u8b58\u4e00\u7a2e\u7279\u5b9a\u6297\u539f\uff0c\u56e0\u800c\u53eb\u505a\u300c\u55ae\u682a\u300d\u6297\u9ad4\u3002<\/p>\n

\u91cd\u7d44\u55ae\u682a\u6297\u9ad4\u662f\u81e8\u5e8a\u6cbb\u7642\u754c\u7684\u65b0\u5bf5\uff0c\u4f46\u9019\u985e\u578b\u7684\u6cbb\u7642\u7528\u85e5\u4e5f\u5bb9\u6613\u5f15\u8d77\u56b4\u91cd\u7684\u904e\u654f\u53cd\u61c9\u3002\u4eca\u5929\u7684\u4e3b\u89d2\uff1a\u91cd\u7d44\u55ae\u682a\u6297\u9ad4\u85e5Cetuximab\uff0c\u57282005\u5e74\u7372\u7f8e\u570b\u98df\u54c1\u85e5\u7269\u7ba1\u7406\u5c40\u6279\u51c6\uff0c\u7528\u4f86\u6cbb\u7642\u5927\u8178\u764c\uff1b\u96a8\u5f8c\u4e5f\u7372\u51c6\u7528\u65bc\u982d\u9838\u7684\u9c57\u72c0\u7d30\u80de\u764c\u7684\u6cbb\u7642\u3002Cetuximab\u80fd\u5920\u5c08\u4e00\u6027\u7684\u7d50\u5408\u5728\u8868\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u5668\u4e0a\uff08epidermal growth factor receptor\uff0cEGFR\uff09\uff0c\u9032\u800c\u9ce9\u4f54\u9d72\u5de2\uff0c\u8b93\u672c\u4f86\u80fd\u7d50\u5408\u4e0aEGFR\u7684\u914d\u9ad4\u7121\u6cd5\u5f97\u5176\u9580\u800c\u5165\u3002EGFR\u6d3b\u5316\u5f8c\u6240\u50b3\u905e\u7684\u8a0a\u606f\u5c0d\u7d30\u80de\u5b58\u6d3b\u8207\u7d30\u80de\u589e\u751f\u90fd\u6975\u70ba\u91cd\u8981\uff0c\u4f46EGFR\u8981\u80fd\u5920\u767c\u63ee\u4f5c\u7528\uff0c\u5f97\u9760\u914d\u9ad4\u8b93EGFR\u55ae\u9ad4\u5169\u5169\u6e4a\u5c0d\u3002\u88abCetuximab\u7d50\u5408\u4e0a\u7684EGFR\uff0c\u53ea\u80fd\u5f62\u55ae\u5f71\u96bb\uff0c\u7121\u6cd5\u6e4a\u6210\u5c0d\uff0c\u9032\u800c\u9054\u5230\u85c9\u7531\u963b\u65b7EGFR\u8a0a\u606f\u50b3\u5c0e\uff0c\u4f86\u6291\u5236\u764c\u75c7\u7d30\u80de\u5b58\u6d3b\u8207\u589e\u751f\u7684\u6cbb\u7642\u76ee\u7684\u3002<\/p>\n

Cetuximab\u662f\u5f88\u6210\u529f\u7684\u91cd\u7d44\u55ae\u682a\u6297\u9ad4\u85e5\u7269\uff0c\u4f46\u5947\u602a\u7684\u662f\uff0c\u5f9e\u81e8\u5e8a\u8a66\u9a57\u671f\u9593\u958b\u59cb\uff0c\u5c31\u96f6\u661f\u7684\u5728\u67d0\u4e9b\u75c5\u4eba\u8eab\u4e0a\u51fa\u73fe\u56b4\u91cd\u904e\u654f\u53cd\u61c9\u3002\u85e5\u54c1\u4eff\u55ae\u4e0a\uff0c\u8aaa\u904e\u654f\u6a5f\u7387\u5927\u6982\u662f\u767e\u5206\u4e4b\u4e09\u3002\u4f46\u8b93\u4eba\u6293\u7834\u982d\u60f3\u4e0d\u660e\u767d\u7684\u662f\uff0c\u51fa\u73fe\u904e\u654f\u53cd\u61c9\u7684\u75c5\u4eba\u6709\u660e\u986f\u5340\u57df\u6027\u3002\u5728\u7f8e\u570b\u5883\u5167\uff0c\u5927\u90e8\u5206\u904e\u654f\u53cd\u61c9\u75c5\u4eba\u90fd\u96c6\u4e2d\u5728\u5317\u5361\u3001\u5bc6\u8607\u91cc\u3001\u7dad\u5409\u5c3c\u4e9e\u3001\u7530\u7d0d\u897f\u3001\u8207\u963f\u80af\u8272\u5dde\u3002\u5728\u9019\u4e9b\u5dde\u88e1\uff0c\u51fa\u73fe\u85e5\u7269\u904e\u654f\u53cd\u61c9\u7684\u75c5\u4eba\u6bd4\u4f8b\u5927\u6982\u662f22%\u3002\u9019\u8b93\u4eba\u76ba\u7709\u7684\u6578\u64da\u4e5f\u6beb\u4e0d\u7559\u60c5\u986f\u793a\u51fa\u85e5\u7269\u904e\u654f\u75c5\u4f8b\u5728\u4e0d\u540c\u7684\u5dde\u4e4b\u9593\uff0c\u53ef\u80fd\u662f\u5feb\u5341\u500d\u7684\u5dee\u8ddd\uff0c\u53ef\u898b\u300c\u5340\u57df\u300d\u4e0d\u55ae\u55ae\u53ea\u662f\u5de7\u5408\u3002<\/p>\n

\u9019\u662f\u70ba\u4ec0\u9ebc\uff1f\u5c0d\u9019\u500b\u554f\u984c\u6df1\u611f\u8208\u8da3\u7684Platts-Mills \u91ab\u751f\uff0c\u958b\u59cb\u7814\u7a76\u9019\u500b\u5927\u8b0e\u984c\u3002Platts-Mills \u91ab\u751f\u7814\u7a76\u5718\u968a\u6536\u96c6\u9ad8\u904e\u654f\u75c5\u4f8b\u5730\u5340\uff0c\u51fa\u73fe\u904e\u654f\u7684\u75c5\u4eba\u8840\u6db2\u6aa2\u9ad4\uff0c\u548c\u5176\u4ed6\u5dde\u7121\u904e\u654f\u53cd\u61c9\u7684\u75c5\u4eba\u3001\u6216\u662f\u5065\u5eb7\u4eba\u7684\u8840\u6db2\u6aa2\u9ad4\u505a\u6bd4\u8f03\u3002\u4ed6\u5011\u767c\u73fe\uff0c\u51fa\u73fe\u56b4\u91cd\u904e\u654f\u53cd\u61c9\u7684\u75c5\u4eba\uff0c\u5728\u7d66\u85e5\u4e4b\u524d\uff0c\u8840\u6db2\u88e1\u9762\u5c31\u5df2\u7d93\u5b58\u5728\u6709\u4e00\u7a2e\u7279\u5225\u7684IgE\u6297\u9ad4\u3002\u9019\u682aIgE\u6297\u9ad4\u80fd\u5920\u8fa8\u8b58\u4e00\u7a2e\u5be1\u7cd6\uff1a\u300c\u03b1-gal\u300d\uff0c\u4e5f\u5c31\u662fgalactose-\u03b1-1,3-galactose\u3002\u300c\u03b1-gal\u300d\u6070\u5de7\u51fa\u73fe\u5728Cetuximab\u6297\u9ad4\u91cd\u934a\u7684\u7cd6\u57fa\u5316\u4fee\u98fe\u4e0a\u3002\u56e0\u6b64\uff0c\u5982\u679c\u75c5\u4eba\u9ad4\u5167\u672c\u8eab\u5c31\u5df2\u7d93\u5b58\u5728\u6709\u8fa8\u8a8d\u300c\u03b1-gal\u300d\u7684IgE\u6297\u9ad4\uff0c\u5728\u6295\u85e5\u4e4b\u5f8c\uff0c\u9019\u4e9bIgE\u6297\u9ad4\u5c31\u6703\u8aa4\u4ee5\u70ba\u6709\u5916\u4f86\u6297\u539f\u5165\u4fb5\uff0c\u800c\u300c\u76e1\u8077\u300d\u7684\u555f\u52d5\u514d\u75ab\u53cd\u61c9\uff0c\u9020\u6210\u60a3\u8005\u5c0d\u85e5\u7269\u904e\u654f\u3002<\/p>\n

Cetuximab\u4e0d\u662f\u552f\u4e00\u542b\u6709\u300c\u03b1-gal\u300d\u7684\u86cb\u767d\u8cea\u3002\u5728\u725b\u8089\u3001\u8c6c\u8089\u3001\u8207\u7f8a\u8089\u7b49\u7d05\u8089\u88e1\uff0c\u4e5f\u90fd\u53ef\u4ee5\u767c\u73fe\u300c\u03b1-gal\u300d\u7684\u8e64\u8de1\u3002\u89e3\u958bCetuximab\u5f15\u8d77\u75c5\u4eba\u904e\u654f\u53cd\u61c9\u8b0e\u5718\u7684Platts-Mills \u91ab\u751f\uff0c\u65bc\u662f\u60f3\u5230\u4e86\u81e8\u5e8a\u4e0a\u90a3\u4e9b\u5c0d\u725b\u8089\u904e\u654f\u7684\u7f55\u898b\u6848\u4f8b\u3002\u9019\u5169\u500b\u770b\u4f3c\u7121\u95dc\u7684\u904e\u654f\u6848\u4f8b\uff0c\u6703\u4e0d\u6703\u90fd\u6709\u53ef\u80fd\u662f\u56e0\u70ba\u75c5\u4eba\u9ad4\u5167\u5df2\u7d93\u5b58\u5728\u7684\u300c\u03b1-gal\u300dIgE\u6297\u9ad4\u5462\uff1f\u9019\u4e9b\u6417\u86cb\u7684\u6297\u9ad4\uff0c\u4e00\u525b\u958b\u59cb\u53c8\u662f\u5982\u4f55\u5728\u75c5\u4eba\u9ad4\u5167\u88ab\u8a98\u767c\u5462\uff1f<\/p>\n

\u8981\u641e\u61c2\u9019\u4e9b\u554f\u984c\uff0c\u9996\u5148\u5f97\u77e5\u9053\u8a98\u767c\u300c\u03b1-gal\u300dIgE\u6297\u9ad4\u7684\u7684\u6297\u539f\uff0c\u5f9e\u54ea\u4f86\uff1fPlatts-Mills \u91ab\u751f\u5be6\u9a57\u5ba4\u8003\u616e\u904e\u5f88\u591a\u53ef\u80fd\u3002\u982d\u865f\u5acc\u7591\u72af\u662f\u771f\u83cc\u6216\u9ef4\u83cc\uff1b\u4f46\u6240\u6709\u75c5\u4eba\u90fd\u6beb\u7121\u4efb\u4f55\u611f\u67d3\u8de1\u8c61\u3002\u4ed6\u5011\u63a5\u8457\u61f7\u7591\u662f\u90a3\u4e9b\u5340\u57df\u88e1\u7279\u6709\u7684\u8815\u87f2\uff0c\u4f46\u67e5\u627e\u4e86\u8815\u87f2\u5206\u5e03\u5716\u537b\u4e5f\u6beb\u7121\u6240\u7372\u3002<\/p>\n

\u6709\u8da3\u7684\u662f\uff0c\u4ed6\u5011\u767c\u73fe\u51fa\u73fe\u904e\u654f\u53cd\u61c9\u7684\u5dde\uff0c\u6975\u70ba\u5de7\u5408\u7684\u548c\u843d\u78ef\u5c71\u6591\u75b9\u71b1\uff08Rocky Mountain spotted fever\uff09\u597d\u767c\u5340\u6975\u70ba\u543b\u5408\u3002\u843d\u78ef\u5c71\u6591\u75b9\u71b1\u662f\u7531\u5e36\u6709\u7acb\u514b\u6b21\u6c0f\u7acb\u514b\u6b21\u9ad4\u7684\u8731\u87f2\u3001\u58c1\u8768\uff08tick\uff09\u6240\u50b3\u67d3\uff0c\u6236\u5916\u3001\u5c71\u5340\u90fd\u662f\u5e38\u6709\u53ef\u80fd\u88ab\u8731\u87f2\u3001\u58c1\u8768\u53ee\u54ac\u7684\u5730\u5340\u3002\u800cPlatts-Mills \u91ab\u751f\u60f3\u5230\uff0c\u4ed6\u6240\u63a5\u89f8\u904e\u5c0d\u725b\u8089\u904e\u654f\u7684\u75c5\u4eba\uff0c\u4e5f\u90fd\u5e38\u8072\u7a31\u904e\u654f\u75c7\u72c0\u662f\u5728\u88ab\u8731\u87f2\u3001\u58c1\u8768\u53ee\u54ac\u4e4b\u5f8c\u624d\u51fa\u73fe\u3002\u65bc\u662f\uff0c\u4ed6\u958b\u59cb\u6aa2\u6e2c\u88ab\u8731\u87f2\u3001\u58c1\u8768\u5f8c\u7684\u75c5\u4eba\uff0c\u8207\u5c0d\u7d05\u8089\u904e\u654f\u7684\u75c5\u4eba\uff0c\u8840\u6db2\u6aa2\u9ad4\u5167\u662f\u4e0d\u662f\u90fd\u6709\u9019\u7a2e\u80fd\u8fa8\u8b58\u300c\u03b1-gal\u300d\u7684IgE\u6297\u9ad4\u3002<\/p>\n

\u4f46\u8981\u8b49\u660e\u9019\u500b\u95dc\u806f\u6027\uff0c\u9664\u4e86\u6536\u96c6\u81e8\u5e8a\u8b49\u64da\uff0cPlatts-Mills \u91ab\u751f\u9084\u6709\u9ede\u8173\u7662\u3002\u64da\u805e\uff0cPlatts-Mills \u91ab\u751f\u89aa\u81ea\u53bb\u85cd\u5dba\u5c71\u8108\u8d70\u4e86\u4e00\u906d\uff0c\u722c\u4e86\u4e94\u5c0f\u6642\u7684\u5c71\uff0c\u5982\u9810\u671f\u822c\u7684\u5728\u56de\u5bb6\u5f8c\uff0c\u6eff\u8173\u662f\u88ab\u8731\u87f2\u3001\u58c1\u8768\u53ee\u54ac\u7684\u75d5\u8de1\u3002\u7136\u5f8c\uff0c\u4ed6\u81ea\u5df1\u8840\u6db2\u6aa2\u9ad4\u5167\uff0c\u4e5f\u7684\u78ba\u51fa\u73fe\u80fd\u548c\u300c\u03b1-gal\u300d\u8d77\u4f5c\u7528\u7684IgE\u6297\u9ad4\u3002\u7a0d\u5f8c\u90a3\u4e00\u5e74\uff0cPlatts-Mills \u91ab\u751f\u4e5f\u7684\u78ba\u5c0d\u725b\u6392\u904e\u654f\u4e86\u3002<\/p>\n

 <\/p>\n

\u53c3\u8003\u8cc7\u6599\uff1a<\/strong><\/p>\n

    \n
  1. Arnold DF, Misbah SA. Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose. N Engl J Med. 2008 Jun 19;358(25):2735; author reply 2735-6. doi: 10.1056\/NEJMc080834. PMID: 18565869<\/li>\n
  2. Chung CH et al. Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose. N Engl J Med. 2008 Mar 13;358(11):1109-17. doi: 10.1056\/NEJMoa074943. PMID: 18337601<\/li>\n
  3. Peter Andrey Smith. Can ticks make you allergic to red meat? New Yorker. March 6, 2014.<\/li>\n
  4. Commins SP. The relevance of tick bites to the production of IgE antibodies to the mammalian oligosaccharide galactose-\u03b1-1,3-galactose. J Allergy Clin Immunol. 2011 May;127(5):1286-93.e6. doi: 10.1016\/j.jaci.2011.02.019. PMID: 21453959.<\/li>\n
  5. Steinke JW, Platts-Mills TA, Commins SP. The alpha-gal story: lessons learned from connecting the dots. J Allergy Clin Immunol. 2015 Mar;135(3):589-96; quiz 597. doi: 10.1016\/j.jaci.2014.12.1947. Review. PMID: 25747720<\/li>\n
  6. van Nunen S. Tick-induced allergies: mammalian meat allergy, tick anaphylaxis and their significance. Asia Pac Allergy. 2015 Jan;5(1):3-16. doi: 10.5415\/apallergy.2015.5.1.3. Epub 2015 Jan 28. Review. PMID: 25653915<\/li>\n<\/ol>\n

    --<\/strong><\/span>
    \n\u4f5c\u8005\uff1a\u99f1\u5b9b\u7433\u3000\u7f8e\u570b\u8056\u8def\u6613\u83ef\u76db\u9813\u5927\u5b78\uff08Washington University in St. Louis\uff09\u514d\u75ab\u5b78\u535a\u58eb\uff0c\u5f9e\u4e8bT\u7d30\u80de\u767c\u80b2\u8207\u6d3b\u5316\u76f8\u95dc\u7684\u8a0a\u606f\u50b3\u5c0e\u7814\u7a76\u3002<\/strong><\/span><\/p>\n

     <\/p>\n

    \"\u52a0\u5165\u597d\u53cb\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

    \u300c\u98df\u7269\u904e\u654f\u300d\u662f\u5e38\u898b\u7684\u7169\u60f1\u3002\u6211\u5011\u807d\u904e\u6709\u4eba\u5c0d\u82b1\u751f\u904e\u654f\u3001\u5c0d\u6d77\u9bae\u904e\u654f\u3001\u5c0d\u725b\u5976\u88fd\u54c1\u904e\u654f\u3002\u4f46\u5c0d\u725b\u6392\u904e\u654f\uff1f\u4f3c\u4e4e\u5f88\u96e3\u60f3\u50cf\u3002\u81e8\u5e8a\u4e0a\u7684\u6848\u4f8b\u6709\uff0c\u4f46\u662f\u6975\u70ba\u5c11\u898b\u3002\u7f8e\u570b\u7dad\u5409\u5c3c\u4e9e\u5927\u5b78\u91ab\u5b78\u9662\u7684\u904e\u654f\u79d1\u91ab\u751f Thomas Platts-Mills\uff0c\u56e0\u7de3\u969b\u6703\u5730\u4e00\u982d\u683d\u9032\u4e86\u9019\u500b\u7f55\u898b\u7684\u3001\u300c\u5c0d\u725b\u6392\u904e\u654f\u300d\u7684\u7814\u7a76\u3002\u800c\u9019\u500b\u5f9e\u81e8\u5e8a\u85e5\u7269\u51fa\u73fe\u8b93\u4eba\u6293\u7834\u982d\u60f3\u4e0d\u901a\u7684\u85e5\u7269\u526f\u4f5c\u7528\uff0c\u5230\u5229\u7528\u79d1\u5b78\u57fa\u790e\u7814\u7a76\u800c\u8ffd\u6839\u7a76\u5e95\u3001\u4e00\u63a2\u7a76\u7adf\u7684\u6545\u4e8b\uff0c\u4e5f\u50cf\u6700\u5f8c\u7684\u7814\u7a76\u6210\u679c\u4e00\u6a23\uff0c\u6709\u8da3\u7684\u8b93\u4eba\u773c\u775b\u767c\u4eae\u3002<\/p>\n","protected":false},"author":20,"featured_media":29439,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,2977,1025],"tags":[3568,3569,702,1387,3566,3567,1330],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/10\/3685784474_aa0cc2e10c_b.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/29432"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=29432"}],"version-history":[{"count":4,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/29432\/revisions"}],"predecessor-version":[{"id":31873,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/29432\/revisions\/31873"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/29439"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=29432"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=29432"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=29432"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}