{"id":27230,"date":"2017-04-20T00:25:41","date_gmt":"2017-04-19T16:25:41","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=27230"},"modified":"2018-07-29T08:15:59","modified_gmt":"2018-07-29T00:15:59","slug":"%e3%80%90%e5%a5%b3%e7%a7%91%e5%ad%b8%e5%ae%b6%e3%80%91%e9%86%a3%e9%a1%9e%e4%bb%a3%e8%ac%9d%e7%9a%84%e5%b7%a8%e4%ba%ba%e2%94%80%e2%94%80%e6%a0%bc%e8%92%82%e2%80%a7%e6%9f%af%e9%87%8c","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=27230","title":{"rendered":"\u3010\u5973\u79d1\u5b78\u5bb6\u3011\u91a3\u985e\u4ee3\u8b1d\u7684\u5de8\u4eba\u2500\u2500\u683c\u8482\u2027\u67ef\u91cc"},"content":{"rendered":"<p><strong><img fetchpriority=\"high\" decoding=\"async\" class=\"alignleft size-full wp-image-27232\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/02\/Gerty_Theresa_Cori.jpg\" alt=\"\" width=\"280\" height=\"396\" \/>\u64b0\u6587\uff5c<\/strong>\u8449\u7da0\u8212<\/p>\n<p>\u5538\u904e\u751f\u5316\u5f88\u5c11\u4e0d\u77e5\u9053\u67ef\u91cc\u5faa\u74b0\uff08Cori cycle\uff09\u7684\u3002\u4eba\u9ad4\u767c\u9175\u4f5c\u7528\u7522\u751f\u7684\u4e73\u9178\u904b\u5230\u809d\u81df\uff0c\u518d\u7d93\u904e\u91a3\u985e\u65b0\u751f\u4f5c\u7528\u7522\u751f\u8461\u8404\u7cd6\uff0c\u7136\u5f8c\u904b\u56de\u7d44\u7e54\uff0c\u53c8\u53ef\u4ee5\u518d\u5ea6\u6c27\u5316\u7522\u751f\u80fd\u91cf\u3002\u4f46\u662f\u6709\u591a\u5c11\u4eba\u77e5\u9053\uff0c\u57281929\u5e74\u683c\u8482\u2027\u67ef\u91cc\uff08Gerty Theresa Cori\uff09\u8207\u5979\u7684\u4e08\u592b\u5361\u723e\uff08Carl Ferdinand Cori\uff09\u5df2\u7d93\u628a\u9019\u500b\u5faa\u74b0\u7d66\u5927\u81f4\u89e3\u51fa\u4f86\u4e86\u5462<a href=\"#_ftn1\" name=\"_ftnref1\">[1]<\/a>\uff1f<\/p>\n<p>\u683c\u8482\u751f\u65bc1896\u5e74\u7684\u5e03\u62c9\u683c\uff0c\u5979\u7684\u540d\u5b57 Gerty \u662f\u5f9e\u4e00\u8258\u5967\u5730\u5229\u7684\u6230\u8266\u4f86\u7684\uff0c\u4f46\u5e38\u88ab\u8aa4\u6703\u6210\u662f\u5c0f\u540d\uff08\u7b46\u8005\u6309\uff1a\u662f\u5426\u4ee5\u70ba\u662fGertrude\uff1f\uff09<a href=\"#_ftn2\" name=\"_ftnref2\">[2]<\/a>\u3002\u5979\u7684\u7236\u89aa\u662f\u5316\u5b78\u5bb6\uff0c\u540c\u6642\u4e5f\u7d93\u71df\u751c\u83dc\u7cd6\u7684\u7cbe\u88fd\u5de5\u5ee0\uff0c\u5bb6\u5883\u4e0d\u932f\uff0c\u6240\u4ee5\u5979\u5341\u6b72\u4ee5\u524d\u5c31\u53ef\u4ee5\u5728\u5bb6\u4e0a\u5b78\uff0c\u5341\u6b72\u4ee5\u5f8c\u5c31\u88ab\u9001\u5230\u300c\u65b0\u5a18\u5b78\u6821\u300d\uff08Finishing School\uff09\u53bb\u7e7c\u7e8c\u53d7\u6559\u80b2\u3002\u7576\u6642\u7684\u5973\u5b69\u5b50\u5e7e\u4e4e\u90fd\u662f\u9001\u5230\u300c\u65b0\u5a18\u5b78\u6821\u300d\u53bb\uff0c\u5728\u90a3\u88e1\u5979\u5011\u5b78\u7fd2\u79ae\u5100\u8207\u5176\u4ed6\u7c21\u55ae\u7684\u8ab2\u7a0b\uff0c\u8b93\u5979\u5011\u53ef\u4ee5\u8207\u672a\u4f86\u7684\u4e08\u592b\u8b1b\u5f97\u4e0a\u8a71\u3002\u4e5f\u56e0\u6b64\uff0c\u96d6\u7136\u6b50\u6d32\u7684\u5927\u5b78\u4e26\u4e0d\u7981\u6b62\u5973\u6027\u5831\u8003\uff0c\u4f46\u7531\u65bc\u65b0\u5a18\u5b78\u6821\u4e0d\u6559\u62c9\u4e01\u6587\u3001\u6578\u5b78\u3001\u7269\u7406\u8207\u5316\u5b78\u9019\u4e9b\u5927\u5b78\u5165\u5b78\u8003\u8a66\u7684\u8003\u79d1\uff0c\u6240\u4ee5\u5973\u6027\u662f\u7121\u6cd5\u4e0a\u5927\u5b78\u7684\u3002<!--more--><\/p>\n<p>\u56e0\u6b64\uff0c\u7576\u683c\u8482\u7684\u53d4\u53d4\u9f13\u52f5\u5979\u8003\u91ab\u5b78\u9662\u7684\u6642\u5019\uff0c\u8e8d\u8e8d\u6b32\u8a66\u7684\u5979\u7acb\u523b\u9047\u5230\u4e00\u500b\u6b98\u9177\u7684\u73fe\u5be6\uff1a\u5979\u8981\u5728\u6700\u77ed\u7684\u6642\u9593\u5167\u88dc\u4fee\u5b8c\u516b\u5e74\u7684\u62c9\u4e01\u6587\u3001\u4e94\u5e74\u7684\u6578\u5b78\u3001\u7269\u7406\u8207\u5316\u5b78\uff01<\/p>\n<p>\u6709\u4e9b\u4eba\u53ef\u80fd\u6703\u5c31\u6b64\u653e\u68c4\u3001\u6709\u4e9b\u4eba\u53ef\u80fd\u6703\u82b1\u5f88\u591a\u5e74\u6162\u6162\u4fee\u3002\u4f46\u662f\u5c0d\u683c\u8482\u4f86\u8aaa\uff0c\u5979\u5728\u77ed\u77ed\u7684\u5169\u5e74\u628a\u9019\u4e9b\u90fd\u88dc\u8d77\u4f86\u3001\u53c3\u52a0\u91ab\u5b78\u9662\u5165\u5b78\u8003\u8a66\uff0c\u4e5f\u8003\u4e0a\u4e86\u3002<\/p>\n<p>\u5230\u4e86\u5e03\u62c9\u683c\u5927\u5b78\uff0c\u5979\u9047\u5230\u4e86\u5f71\u97ff\u5979\u751f\u547d\u6700\u91cd\u8981\u7684\u4e00\u500b\u4eba\u8207\u4e00\u4ef6\u4e8b\uff1a\u5979\u611b\u4e0a\u4e86\u751f\u7269\u5316\u5b78\uff0c\u6c7a\u5b9a\u4e0d\u8981\u7576\u81e8\u5e8a\u91ab\u5e2b\u3001\u8981\u4f5c\u4e00\u8f29\u5b50\u7684\u7814\u7a76\uff1b\u5979\u9047\u5230\u4e86\u5979\u9019\u4e00\u751f\u7684\u646f\u611b\u4ee5\u53ca\u7814\u7a76\u4f19\u4f34\uff1a\u5361\u723e\u3002<\/p>\n<p>\u5bb3\u7f9e\u5167\u5411\u7684\u5361\u723e\u8207\u843d\u843d\u5927\u65b9\u7684\u683c\u8482\uff0c\u5728\u8a31\u591a\u65b9\u9762\u90fd\u4e92\u88dc\u3002\u4ed6\u5011\u90fd\u559c\u6b61\u722c\u5c71\u3001\u6ed1\u96ea\uff0c\u5f88\u5feb\u7684\u5169\u4eba\u5c31\u4e92\u76f8\u8a8d\u5b9a\u4e86\u3002\u9664\u4e86\u4e00\u8d77\u8b80\u66f8\u3001\u722c\u5c71\u3001\u6ed1\u96ea\uff0c\u4ed6\u5011\u4e5f\u4e00\u8d77\u4f5c\u7814\u7a76\uff0c\u767c\u8868\u4e86\u4e00\u7bc7\u8ad6\u6587\u3002\u7562\u696d\u7684\u90a3\u5e74\uff0c\u4ed6\u5011\u7d50\u5a5a\u4e86\u3002\u7531\u65bc\u683c\u8482\u662f\u7336\u592a\u4eba\uff0c\u70ba\u4e86\u8981\u8207\u5361\u723e\u7d50\u5a5a\uff0c\u5979\u653e\u68c4\u4e86\u81ea\u5df1\u7684\u5b97\u6559\uff0c\u6539\u4fe1\u5929\u4e3b\u6559\u3002<\/p>\n<p>\u6b50\u6230\u5f8c\u7684\u6771\u6b50\u7d93\u6fdf\u72c0\u6cc1\u4e26\u4e0d\u597d\u3002\u7531\u65bc\u71df\u990a\u4e0d\u826f\uff0c\u4f7f\u5f97\u683c\u8482\u4e00\u5ea6\u7f79\u60a3\u4e7e\u773c\u75c7\uff1b\u52a0\u4e0a\u7576\u6642\u6b50\u6d32\u53cd\u7336\u592a\u7684\u6c23\u6c1b\u9ad8\u6f32\uff0c\u5361\u723e\u8a8d\u70ba\u5927\u6230\u9072\u65e9\u6703\u518d\u5ea6\u7206\u767c\u3002\u65bc\u662f\u3002\u5169\u4eba\u6c7a\u5b9a\u8981\u5230\u7f8e\u570b\u53bb\u5c0b\u627e\u6a5f\u6703\u3002\u5361\u723e\u57281922\u5e74\u5230\u4e86\u6c34\u725b\u57ce\u7684\u764c\u75c7\u4e2d\u5fc3\uff0c\u534a\u5e74\u5f8c\u683c\u8482\u4e5f\u5230\u4e86\u7f8e\u570b\u3002<\/p>\n<p>\u96d6\u7136\u764c\u75c7\u4e2d\u5fc3\u8a2d\u5099\u5f88\u597d\uff0c\u5169\u4eba\u7684\u7814\u7a76\u4e5f\u7a81\u98db\u731b\u9032\uff08\u4e5d\u5e74\u9593\u5169\u4eba\u7e3d\u5171\u767c\u8868\u4e86\u4e94\u5341\u7bc7\u8ad6\u6587\u3001\u89e3\u51fa\u4e86\u6709\u540d\u7684\u67ef\u91cc\u5faa\u74b0\uff09\uff0c\u4f46\u5728\u764c\u75c7\u4e2d\u5fc3\u7814\u7a76\u91a3\u985e\u4ee3\u8b1d\u7e3d\u89ba\u5f97\u8207\u5176\u4ed6\u4eba\u683c\u683c\u4e0d\u5165\uff1b\u52a0\u4e0a\u4e3b\u4efb\u4e0d\u5141\u8a31\u683c\u8482\u5728\u5361\u723e\u7684\u5be6\u9a57\u5ba4\u88e1\u9762\u5de5\u4f5c\uff0c\u65bc\u662f\u4ed6\u5011\u6c7a\u5b9a\u627e\u5c0b\u5176\u4ed6\u7684\u5de5\u4f5c\u6a5f\u6703\u3002<\/p>\n<p>\u5373\u4f7f\u4e0d\u7b97\u8207\u5361\u723e\u5171\u540c\u767c\u8868\u7684\u8ad6\u6587\uff0c\u5149\u662f\u683c\u8482\u81ea\u5df1\u5c31\u767c\u8868\u4e86\u5341\u4e00\u7bc7\uff0c\u4f46\u7576\u4ed6\u5011\u958b\u59cb\u627e\u5de5\u4f5c\u6642\uff0c\u537b\u6c92\u6709\u4eba\u8981\u7d66\u5979\u5de5\u4f5c\u3002\u7576\u6642\u5728\u7f8e\u570b\uff0c\u592b\u59bb\u540c\u6642\u5728\u5be6\u9a57\u5ba4\u88e1\u5de5\u4f5c\u7684\u4e26\u4e0d\u5c11\u898b\uff1b\u4f46\u901a\u5e38\u59bb\u5b50\u662f\u64d4\u4efb\u4e08\u592b\u7684\u5be6\u9a57\u5ba4\u52a9\u7406\uff0c\u800c\u4e14\u5982\u679c\u4e08\u592b\u5f80\u751f\u4e86\u3001\u6216\u8005\u4ed6\u5011\u96e2\u5a5a\u4e86\uff0c\u5973\u65b9\u99ac\u4e0a\u5c31\u6703\u5931\u696d\u3002<\/p>\n<p>\u683c\u8482\u4e26\u4e0d\u60f3\u53ea\u662f\u7576\u500b\u6c92\u6709\u4fdd\u969c\u7684\u5be6\u9a57\u5ba4\u52a9\u7406\u3002\u7562\u7adf\uff0c\u4ee5\u5979\u7684\u8070\u660e\u624d\u667a\u8207\u5de5\u4f5c\u8868\u73fe\uff0c\u5979\u4e26\u4e0d\u905c\u65bc\u4efb\u4f55\u4e00\u500b\u7537\u4eba\uff1b\u751a\u81f3\uff0c\u8a31\u591a\u7537\u6027\u7684\u6559\u6388\u90fd\u4e0d\u5982\u5979\u3002\u5361\u723e\u70ba\u4e86\u5979\uff0c\u62d2\u7d55\u4e86\u5eb7\u4e43\u723e\u5927\u5b78\u3001\u591a\u502b\u591a\u5927\u5b78\uff0c\u56e0\u70ba\u4ed6\u5011\u4e0d\u9858\u610f\u7d66\u683c\u8482\u4e00\u4efd\u5de5\u4f5c\u3002\u7576\u4ed6\u56e0\u70ba\u540c\u6a23\u7684\u7406\u7531\uff0c\u62d2\u7d55\u4e86\u7f85\u5207\u65af\u7279\u5927\u5b78\u7d66\u4ed6\u7684\u8058\u66f8\u6642\uff0c\u6821\u65b9\u4eba\u58eb\u8981\u6c42\u53e6\u5916\u8ddf\u683c\u8482\u804a\u804a\u3002<\/p>\n<p>\u4ed6\u5011\u8ddf\u5979\u8aaa\uff0c\u5979\u9019\u6a23\u5f71\u97ff\u4ed6\u7684\u4e08\u592b\uff0c\u5c0d\u4ed6\u4e8b\u696d\u7684\u767c\u5c55\u662f\u6709\u5bb3\u7684\uff1b\u4ed6\u5011\u9084\u8aaa\uff0c\u5728\u7f8e\u570b\uff0c\u6c92\u6709\u4e08\u592b\u8207\u59bb\u5b50\u5728\u540c\u4e00\u500b\u7cfb\u5de5\u4f5c\u3002\u7576\u5834\uff0c\u683c\u8482\u6c92\u6709\u8aaa\u4ec0\u9ebc\uff0c\u4f46\u56de\u53bb\u5f8c\u54ed\u4e86<a href=\"#_ftn3\" name=\"_ftnref3\">[3]<\/a>\u3002<\/p>\n<p>\u5361\u723e\u9084\u662f\u62d2\u7d55\u4e86\u7f85\u5207\u65af\u7279\u5927\u5b78\u3002\u7d42\u65bc\uff0c\u57281931\u5e74\uff0c\u96d6\u4e0d\u6eff\u610f\u4f46\u53ef\u63a5\u53d7\u7684\u6a5f\u6703\u4f86\u4e86\u3002\u897f\u96c5\u5716\u7684\u83ef\u76db\u9813\u5927\u5b78\u91ab\u5b78\u9662\u9858\u610f\u540c\u6642\u63d0\u4f9b\u5169\u592b\u59bb\u5de5\u4f5c\uff1a\u5361\u723e\u53bb\u7576\u85e5\u5b78\u7cfb\u7684\u7cfb\u4e3b\u4efb\u3001\u683c\u8482\u5247\u6210\u70ba\u4ed6\u5be6\u9a57\u5ba4\u7684\u7814\u7a76\u52a9\u7406\u3002<\/p>\n<p>\u96d6\u7136\u807d\u8d77\u4f86\u8ddf\u5be6\u9a57\u5ba4\u52a9\u7406\u5dee\u4e0d\u4e86\u591a\u5c11\u3001\u800c\u4e14\u85aa\u6c34\u53ea\u6709\u5361\u723e\u7684\u5169\u6210\uff0c\u4f46\u662f\u9019\u662f\u500b\u6b63\u5f0f\u7f3a\u3002\u65bc\u662f\u5169\u592b\u59bb\u5c31\u9019\u6a23\u642c\u5230\u8056\u8def\u6613\u4e86\u3002<\/p>\n<p>\u5728\u6c34\u725b\u57ce\u6642\uff0c\u4ed6\u5011\u5728\u5b8c\u6574\u7684\u52d5\u7269\uff08\u5927\u9f20\uff09\u9ad4\u5167\u7814\u7a76\u91a3\u985e\u4ee3\u8b1d\uff1b\u5230\u4e86\u8056\u8def\u6613\uff0c\u4ed6\u5011\u6c7a\u5b9a\u958b\u59cb\u4f7f\u7528\u7d44\u7e54\uff08\u9752\u86d9\u7684\u808c\u8089\uff09\u3002\u96d6\u7136\u5b8c\u6574\u7684\u52d5\u7269\u4e0d\u7528\u64d4\u5fc3\u7d44\u7e54\u4fdd\u5b58\u7684\u554f\u984c\uff0c\u4f46\u662f\u4ee3\u8b1d\u7684\u767c\u751f\u592a\u5feb\u592a\u8907\u96dc\uff0c\u6539\u7528\u7d44\u7e54\u53ef\u4ee5\u5728\u63a7\u5236\u6eab\u5ea6\u8207\u74b0\u5883\u7684\u72c0\u6cc1\u4e0b\uff0c\u8b93\u5be6\u9a57\u66f4\u5bb9\u6613\u63a7\u5236\u3001\u7d50\u679c\u4e5f\u66f4\u5bb9\u6613\u89e3\u91cb\u3002<\/p>\n<p>\u73fe\u5728\u7684\u6211\u5011\uff0c\u5f88\u96e3\u60f3\u50cf\u90a3\u500b\u5e74\u4ee3\u7684\u4eba\u4f5c\u5be6\u9a57\u7684\u56f0\u96e3\u3002\u6211\u5011\u9700\u8981\u5316\u5b78\u85e5\u54c1\uff0c\u62ff\u8d77\u96fb\u8a71\u6253\u7d66\u5ee0\u5546\u5373\u53ef\uff1b\u4ed6\u5011\u9700\u8981\u5316\u5b78\u85e5\u54c1\uff0c\u8981\u81ea\u5df1\u7d14\u5316\u3001\u81ea\u5df1\u88fd\u9020\u3002\u70ba\u4e86\u78ba\u5b9a\u5be6\u9a57\u6c92\u6709\u554f\u984c\uff0c\u683c\u8482\u56b4\u683c\u7684\u8a13\u7df4\u5be6\u9a57\u5ba4\u7684\u6bcf\u4e00\u500b\u6210\u54e1\uff0c\u78ba\u5b9a\u6240\u6709\u7684\u5316\u5b78\u85e5\u54c1\u90fd\u4ee5\u76f8\u540c\u7684\u6a19\u6e96\u4f86\u88fd\u9020\u8207\u7d14\u5316\u3002\u5169\u592b\u59bb\u5728\u5be6\u9a57\u5ba4\u88e1\u5206\u5de5\u5408\u4f5c\uff1a\u683c\u8482\u8ca0\u8cac\u898f\u5283\u5be6\u9a57\u3001\u505a\u5be6\u9a57\uff0c\u4e00\u6709\u7d50\u679c\u99ac\u4e0a\u8ddf\u5361\u723e\u8a0e\u8ad6\uff1b\u5361\u723e\u5f9e\u5be6\u9a57\u7d50\u679c\u53bb\u63a8\u8ad6\u53ef\u80fd\u7684\u6a5f\u5236\u3002<\/p>\n<p>1936\u5e74\uff0c\u4ed6\u5011\u552f\u4e00\u7684\u5152\u5b50\u6e6f\u59c6\u8a95\u751f\u4e86\u3002\u683c\u8482\u5de5\u4f5c\u5230\u5206\u5a29\u7684\u524d\u4e00\u5929\uff0c\u4e09\u5929\u5f8c\u5979\u53c8\u56de\u4f86\u4e0a\u73ed\u4e86\u3002\u5169\u592b\u59bb\u5728\u90a3\u4e00\u5e74\u767c\u73fe\u4e86\u809d\u91a3\u5206\u89e3\u7684\u91cd\u8981\u7522\u7269\uff1a\u8461\u8404\u7cd6 1-\u78f7\u9178\uff08glucose 1-phosphate, G 1-P\uff09\uff0c\u4e5f\u88ab\u7a31\u70ba\u67ef\u91cc\u916f\uff08Cori ester\uff09\u3002\u6c92\u591a\u4e45\uff0c\u78f7\u9178\u5316\u9176\uff08phosphorylase\uff09-- \u809d\u91a3\u5206\u89e3\u7684\u91cd\u8981\u9175\u7d20 \u2013 \u4e5f\u88ab\u4ed6\u5011\u767c\u73fe\u4e86\u3002\u57281939\u5e74\u591a\u502b\u591a\u7684\u4e00\u500b\u570b\u969b\u6703\u8b70\u4e0a\uff0c\u5361\u723e\u7b2c\u4e00\u6b21\u7576\u773e\u5c55\u793a\u5927\u5206\u5b50\uff08\u809d\u91a3\uff09\u53ef\u4ee5\u5728\u8a66\u7ba1\u88e1\u5408\u6210\u3002\u5728\u904e\u53bb\uff0c\u5927\u5bb6\u90fd\u8a8d\u70ba\u5927\u5206\u5b50\u53ea\u6709\u5728\u751f\u7269\u9ad4\u5167\u624d\u80fd\u5408\u6210\u5462\uff01<\/p>\n<p>\u96d6\u7136\u6709\u9019\u9ebc\u591a\u7684\u91cd\u8981\u767c\u73fe\uff0c\u4f46\u771f\u6b63\u8b93\u683c\u8482\u62ff\u5230\u6b63\u5f0f\u7684\u6559\u8077\u7684\u95dc\u9375\uff0c\u537b\u4e0d\u662f\u5979\u7684\u7814\u7a76\uff0c\u800c\u662f\u7b2c\u4e8c\u6b21\u4e16\u754c\u5927\u6230\u3002\u4e8c\u6230\u671f\u9593\uff0c\u56e0\u70ba\u7f8e\u570b\u570b\u5167\u7f3a\u5c11\u52de\u52d5\u529b\uff0c\u5973\u6027\u5728\u8077\u5834\u7684\u5730\u4f4d\u8b8a\u5f97\u4e0d\u53ef\u6216\u7f3a\uff1b\u65bc\u662f\u5979\u7d42\u65bc\u57281944\u5e74\u7d42\u65bc\u5f97\u5230\u7684\u6b63\u5f0f\u7684\u6559\u8077\u3002<\/p>\n<p>\u5169\u592b\u59bb\u57281947\u5e74\u7372\u9812\u8afe\u8c9d\u723e\u91ab\u5b78\u6216\u751f\u7406\u5b78\u734e\u3002\u5728\u5f97\u6089\u5f97\u734e\u7684\u5169\u500b\u591a\u6708\u524d\uff0c\u683c\u8482\u767c\u73fe\u81ea\u5df1\u5f97\u4e86\u4e0d\u6cbb\u4e4b\u75c7\uff1a\u9aa8\u9ad3\u7e96\u7dad\u5316\uff08myelofibrosis\uff09\u3002\u5979\u7684\u9aa8\u9ad3\u4e0d\u518d\u70ba\u5979\u9020\u8840\uff0c\u800c\u662f\u88ab\u7e96\u7dad\u7d44\u7e54\u6240\u53d6\u4ee3\u3002\u91ab\u751f\u544a\u8a34\u5979\uff0c\u63a5\u4e0b\u4f86\u90fd\u5f97\u9760\u8457\u8f38\u8840\u904e\u6d3b\u3002<\/p>\n<figure id=\"attachment_27231\" aria-describedby=\"caption-attachment-27231\" style=\"width: 500px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-27231\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/02\/cori_cori_lab_photo.jpg\" width=\"500\" height=\"347\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/02\/cori_cori_lab_photo.jpg 980w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/02\/cori_cori_lab_photo-600x416.jpg 600w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/02\/cori_cori_lab_photo-800x555.jpg 800w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><figcaption id=\"caption-attachment-27231\" class=\"wp-caption-text\">Drs. Carl and Gerty Cori in their laboratory at the Washington University School of Medicine in St. Louis, Missouri, 1947.<\/figcaption><\/figure>\n<p>\u9760\u8457\u8f38\u8840\uff0c\u683c\u8482\u53c8\u591a\u6d3b\u4e86\u5341\u5e74\uff1b\u5979\u4e00\u76f4\u5de5\u4f5c\u5230\u6700\u5f8c\u4e00\u500b\u6708\u3002\u5728\u5979\u96e2\u4e16\u4ee5\u5f8c\u4e09\u5e74\uff0c\u5361\u723e\u518d\u5a5a\u4e86\u3002\u5931\u53bb\u4e86\u683c\u8482\u4ee5\u5f8c\uff0c\u5361\u723e\u9084\u662f\u7e7c\u7e8c\u9032\u884c\u7814\u7a76\uff0c\u4f46\u5c11\u4e86\u683c\u8482 \u2013 \u67ef\u91cc\u5be6\u9a57\u5ba4\u7684\u9748\u9b42\u4eba\u7269 -- \u5361\u723e\u7684\u8ad6\u6587\u767c\u8868\u6578\u91cf\u4e5f\u5927\u4e0d\u5982\u524d\u4e86\u3002\u96d6\u7136\u5169\u592b\u59bb\u552f\u4e00\u7684\u5152\u5b50\u62d2\u7d55\u50b3\u627f\u8863\u7f3d\uff08\u6e6f\u59c6\u5f8c\u4f86\u6210\u70ba\u88fd\u85e5\u516c\u53f8Sigma-Aldrich\u7684\u7e3d\u88c1\uff0c\u65bc2000\u5e74\u9000\u4f11<a href=\"#_ftn4\" name=\"_ftnref4\">[4]<\/a>\uff09\uff0c\u4f46\u662f\u5f9e\u4ed6\u5011\u5be6\u9a57\u5ba4\u51fa\u4e86\u516b\u500b\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\uff1a\u4ed6\u5011\u592b\u5a66\u3001\u5b54\u4f2f\u683c\uff08Arthur Kornberg\uff0c1959\u8afe\u8c9d\u723e\u751f\u7406\u91ab\u5b78\u734e\uff09\u3001\u85a9\u745f\u862d\uff08Earl W. Sutherland\uff0c1971\u8afe\u8c9d\u723e\u751f\u7406\u91ab\u5b78\u734e\uff09\u3001\u514b\u96f7\u5e03\u65af\uff08Edwin G. Krebs\uff0c1992\u8afe\u8c9d\u723e\u751f\u7406\u91ab\u5b78\u734e\uff09<a href=\"#_ftn5\" name=\"_ftnref5\">[5]<\/a>\u3001\u5967\u55ac\u4e9e\uff08Severo Ochoa\uff0c1959\u8afe\u8c9d\u723e\u751f\u7406\u91ab\u5b78\u734e\uff09\u3001\u5fb7\u00b7\u8fea\u592b\uff08Christian R. de Duve\uff0c1974\u8afe\u8c9d\u723e\u751f\u7406\u91ab\u5b78\u734e\uff09\u8207\u840a\u6d1b\u4f0a\u723e\uff08Luis F. Leloir\uff0c1970\u8afe\u8c9d\u723e\u5316\u5b78\u734e\uff09\uff0c\u4e5f\u53ef\u8aaa\u662f\u5f8c\u7e7c\u6709\u4eba\u4e86\u3002\u800c\u67ef\u91cc\u7531\u65bc\u81ea\u5df1\u7684\u8655\u5883\uff0c\u4e5f\u4e0d\u541d\u65bc\u5354\u52a9\u5be6\u9a57\u5ba4\u88e1\u7684\u5973\u6027\u5de5\u4f5c\u4eba\u54e1\uff1a\u540c\u4ec1\u5bb6\u88e1\u767c\u751f\u7dca\u6025\u72c0\u6cc1\uff0c\u5979\u6703\u5077\u5077\u585e\u9322\u7d66\u5979\u5011\uff1b\u540c\u4ec1\u7684\u8913\u6bcd\u81e8\u6642\u7f3a\u5e2d\uff0c\u5979\u4e5f\u6703\u628a\u81ea\u5df1\u7684\u7ba1\u5bb6\u51fa\u501f\u3002\u96d6\u7136\u5979\u5728\u5be6\u9a57\u5ba4\u88e1\u662f\u500b\u56b4\u683c\u7684\u8001\u95c6\uff0c\u4f46\u540c\u4ec1\u66f4\u8a18\u5f97\u5979\u7684\uff0c\u9664\u4e86\u9019\u4e9b\u6177\u6168\u5927\u5ea6\u7684\u884c\u70ba\u4e4b\u5916\uff0c\u9084\u6709\u5979\u90a3\u4ee4\u4eba\u6298\u670d\u7684\u535a\u5b78\uff1a\u9664\u4e86\u5c08\u696d\u7684\u8ad6\u6587\u4e00\u51fa\u7248\u5c31\u99ac\u4e0a\u770b\u5b8c\u4ee5\u5916\uff0c\u5979\u4e00\u9031\u9084\u8981\u8b80\u4e94\u5230\u4e03\u672c\u66f8\uff0c\u9031\u672b\u9084\u53c3\u52a0\u8a31\u591a\u6236\u5916\u8207\u85dd\u6587\u6d3b\u52d5\u3002\u5979\u7684\u540c\u4ec1\u8207\u670b\u53cb\u90fd\u8a8d\u70ba\uff0c\u5979\u662f\u6975\u70ba\u5c11\u898b\u7684\u9802\u5c16\u5b78\u8005\uff01<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"#_ftnref1\" name=\"_ftn1\">[1]<\/a> Darlene R. Stille. Extraordinary Women Scientists. Childrens Press. ISBN 0-516-40585-3<\/p>\n<p><a href=\"#_ftnref2\" name=\"_ftn2\">[2]<\/a> <a href=\"https:\/\/en.wikipedia.org\/wiki\/Gerty_Cori\" target=\"_blank\" rel=\"noopener noreferrer\">Wikipedia. Gerty Cori.\u00a0<\/a><\/p>\n<p><a href=\"#_ftnref3\" name=\"_ftn3\">[3]<\/a> Sharon Bertsch McGrayne. Nobel Prize Women in Science. 2<sup>nd<\/sup> edition. Joseph Henry Press. ISBN 0-309-07270-0<\/p>\n<p><a href=\"#_ftnref4\" name=\"_ftn4\">[4]<\/a> <a href=\"http:\/\/files.shareholder.com\/downloads\/SIGMA\/0x0x267435\/a1b564cb-4c92-4b4c-bb7b-b39c6cd2492b\/SIAL_News_2000_11_14_General.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Sigma-Aldrich Chairman Tom Cori Announces Retirement; CEO David Harvey Elected Chairman<\/a><\/p>\n<p><a href=\"#_ftnref5\" name=\"_ftn5\">[5]<\/a> \u9019\u500b\u514b\u96f7\u5e03\u65af\u4e0d\u662f\u767c\u73fe\u514b\u6c0f\u5faa\u74b0\u7684\u6f22\u65af\u2027\u514b\u96f7\u5e03\u65af\uff08Hans Adolf Krebs\uff0c1900\u20131981\uff09\u3002<\/p>\n<p><strong>--<\/strong><br \/>\n<span style=\"color: #333399;\"><strong>\u4f5c\u8005\uff1a\u8449\u7da0\u8212\u3000\u6148\u6fdf\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb\u52a9\u7406\u6559\u6388\uff0c\u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b\uff0c\u5f9e\u4e8b\u79d1\u666e\u6587\u7ae0\u5beb\u4f5c\u3002<\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u683c\u8482\u751f\u65bc1896\u5e74\u7684\u5e03\u62c9\u683c\uff0c\u5979\u7684\u540d\u5b57 Gerty \u662f\u5f9e\u4e00\u8258\u5967\u5730\u5229\u7684\u6230\u8266\u4f86\u7684\uff0c\u4f46\u5e38\u88ab\u8aa4\u6703\u6210\u662f\u5c0f\u540d\u3002\u5979\u7684\u7236\u89aa\u662f\u5316\u5b78\u5bb6\uff0c\u540c\u6642\u4e5f\u7d93\u71df\u751c\u83dc\u7cd6\u7684\u7cbe\u88fd\u5de5\u5ee0\uff0c\u5bb6\u5883\u4e0d\u932f\uff0c\u6240\u4ee5\u5979\u5341\u6b72\u4ee5\u524d\u5c31\u53ef\u4ee5\u5728\u5bb6\u4e0a\u5b78\uff0c\u5341\u6b72\u4ee5\u5f8c\u5c31\u88ab\u9001\u5230\u300c\u65b0\u5a18\u5b78\u6821\u300d\uff08Finishing School\uff09\u53bb\u7e7c\u7e8c\u53d7\u6559\u80b2\u3002\u7576\u6642\u7684\u5973\u5b69\u5b50\u5e7e\u4e4e\u90fd\u662f\u9001\u5230\u300c\u65b0\u5a18\u5b78\u6821\u300d\u53bb\uff0c\u5728\u90a3\u88e1\u5979\u5011\u5b78\u7fd2\u79ae\u5100\u8207\u5176\u4ed6\u7c21\u55ae\u7684\u8ab2\u7a0b\uff0c\u8b93\u5979\u5011\u53ef\u4ee5\u8207\u672a\u4f86\u7684\u4e08\u592b\u8b1b\u5f97\u4e0a\u8a71\u3002\u4e5f\u56e0\u6b64\uff0c\u96d6\u7136\u6b50\u6d32\u7684\u5927\u5b78\u4e26\u4e0d\u7981\u6b62\u5973\u6027\u5831\u8003\uff0c\u4f46\u7531\u65bc\u65b0\u5a18\u5b78\u6821\u4e0d\u6559\u62c9\u4e01\u6587\u3001\u6578\u5b78\u3001\u7269\u7406\u8207\u5316\u5b78\u9019\u4e9b\u5927\u5b78\u5165\u5b78\u8003\u8a66\u7684\u8003\u79d1\uff0c\u6240\u4ee5\u5973\u6027\u662f\u7121\u6cd5\u4e0a\u5927\u5b78\u7684\u3002<\/p>\n","protected":false},"author":20,"featured_media":27231,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,1042,2977],"tags":[3233,3283,3234,3235,1454],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2017\/02\/cori_cori_lab_photo.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/27230"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=27230"}],"version-history":[{"count":3,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/27230\/revisions"}],"predecessor-version":[{"id":31720,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/27230\/revisions\/31720"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/27231"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=27230"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=27230"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=27230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}