

{"id":26323,"date":"2016-12-16T00:00:29","date_gmt":"2016-12-15T16:00:29","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=26323"},"modified":"2018-08-03T15:30:02","modified_gmt":"2018-08-03T07:30:02","slug":"%e3%80%90%e6%8e%a2%e7%b4%a216-6%e3%80%91%e8%a1%80%e7%ae%a1%e7%9a%84%e7%94%9f%e6%88%90%ef%bc%9a%e5%a4%9a%e7%b4%b0%e8%83%9e%e7%94%9f%e7%89%a9%e9%ab%94%e5%85%a7%e9%ab%98%e9%80%9f%e5%85%ac%e8%b7%af","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=26323","title":{"rendered":"\u3010\u63a2\u7d2216-6\u3011\u8840\u7ba1\u7684\u751f\u6210\uff1a\u591a\u7d30\u80de\u751f\u7269\u9ad4\u5167\u9ad8\u901f\u516c\u8def\u7684\u69cb\u7bc9\u904e\u7a0b"},"content":{"rendered":"<p><strong><img fetchpriority=\"high\" decoding=\"async\" class=\"alignleft wp-image-26325\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/12\/16-6-Artery-1.jpeg\" alt=\"16-6-artery\" width=\"450\" height=\"312\">\u8b1b\u5e2b\uff5c<\/strong>\u81fa\u5927\u751f\u79d1\u7cfb\u6559\u6388 \u674e\u5fc3\u4e88<strong><br \/>\n\u64b0\u6587\uff5c<\/strong>\u694a\u4e8e\u8473<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u4eba\u9ad4\u5167\u7684\u9ad8\u901f\u516c\u8def<\/strong><\/span><\/p>\n<p>\u672c\u5834\u6f14\u8b1b\u95dc\u9375\u5b57\u8a5e\uff0c\u5206\u5225\u662f\u8840\u7ba1\u751f\u6210\uff08Angiogenesis\uff09\u3001\u5167\u76ae\u7d30\u80de\uff08Endothelial cell\uff09\u3001\u764c\u75c7\uff08Cancer\uff09\u3001\u764c\u7d30\u80de\u8f49\u79fb\uff08Metastasis\uff09\u548c\u4fc3\u8840\u7ba1\u751f\u6210\u4ee5\u53ca\u6291\u5236\u8840\u7ba1\u751f\u6210\u4e4b\u56e0\u5b50\uff08Anti-and pro-angiogenic factor\uff09\u3002\u900f\u904e\u5be6\u969b\u7684\u4f8b\u5b50\u3001\u6709\u8da3\u7684\u4ecb\u7d39\u4ee5\u53ca\u89aa\u8eab\u7d93\u9a57\uff0c\u8b93\u6211\u5011\u5728\u6f14\u8b1b\u7684\u904e\u7a0b\u4e2d\u5c0d\u8840\u7ba1\u751f\u6210\u7684\u6a5f\u5236\u6709\u66f4\u591a\u7684\u8a8d\u8b58\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u8840\u7ba1\u751f\u6210\uff08Angiogenesis\uff09<\/strong><\/span><\/p>\n<p>\u8840\u7ba1\u751f\u6210\u6709\u5169\u7a2e\uff0c\u5206\u5225\u662f Angiogenesis \u4ee5\u53ca Vasculogenesis\u3002\u8840\u7ba1\u7d50\u69cb\u5065\u5168\u5982\u540c\u6a39\u679d\u7684\u6a23\u8c8c\uff0c\u518d\u884d\u751f\u51fa\u5c0f\u679d\u5e79\u7684\u904e\u7a0b\u7a31\u70ba Angiogenesis\u3002\u800c Vasculogenesis \u5247\u662f\u8840\u7ba1\u6bcd\u7d30\u80de\u805a\u5408\u5f62\u6210\u8840\u7ba1\u7684\u904e\u7a0b\uff0c\u5982\u540c\u6a39\u679d\u5f9e\u7121\u5230\u6709\u7684\u6a23\u8c8c\u3002\u6b64\u6f14\u8b1b\u4e2d\u7684\u8840\u7ba1\u751f\u6210\u4e3b\u8981\u662f\u805a\u7126\u5728\u524d\u8005\u7684\u90e8\u5206\u3002<!--more--><\/p>\n<p>\u8840\u7ba1\u7684\u751f\u6210\u4e00\u822c\u767c\u751f\u5728\u80da\u80ce\u767c\u80b2\u7684\u904e\u7a0b\u4e2d\uff0c\u5f80\u5f80\u9700\u8981\u5927\u91cf\u7684\u990a\u5206\u4ee5\u53ca\u4ee3\u8b1d\uff0c\u65b0\u751f\u4e4b\u8840\u7ba1\u751f\u6210\u624d\u8db3\u4ee5\u4f9b\u61c9\u5feb\u901f\u767c\u80b2\u4e4b\u80da\u80ce\u6b63\u5e38\u4e4b\u751f\u9577\u6240\u9700\uff1b\u5728\u50b7\u53e3\u7652\u5408\u7684\u6642\u5019\u4e5f\u6703\u9700\u8981\u8840\u7ba1\u7684\u751f\u6210\uff0c\u56e0\u70ba\u65b0\u751f\u4e4b\u7d44\u7e54\u9700\u8981\u5927\u91cf\u7684\u71df\u990a\u6210\u5206\u4ee5\u53ca\u4fee\u88dc\u7269\u8cea\uff0c\u514d\u75ab\u7cfb\u7d71\u7684\u6210\u54e1\u4ea6\u5728\u6b64\u904e\u7a0b\u4e2d\u626e\u6f14\u91cd\u8981\u7684\u89d2\u8272\uff0c\u800c\u65b0\u751f\u4e4b\u8840\u7ba1\u6240\u904b\u9001\u81f3\u53d7\u50b7\u7684\u7d44\u7e54\u5167\uff1b\u7576\u816b\u7624\u5f62\u6210\u6642\u6703\u5206\u6ccc\u523a\u6fc0\u8840\u7ba1\u65b0\u751f\u4e4b\u7269\u8cea\uff0c\u4ee5\u523a\u6fc0\u5bbf\u4e3b\u7522\u751f\u65b0\u751f\u8840\u7ba1\u662f\u4e00\u500b\u91cd\u8981\u4e14\u5fc5\u9808\u7684\u904e\u7a0b\uff0c\u6700\u5f8c\u5f62\u6210\u60e1\u6027\u816b\u7624\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u5167\u76ae\u7d30\u80de\uff08Endothelial cell\uff09<\/strong><\/span><\/p>\n<p>\u4e0d\u7ba1\u662f\u52d5\u8108\u3001\u975c\u8108\u6216\u8005\u662f\u5fae\u8840\u7ba1\uff0c\u4eba\u9ad4\u5167\u6240\u6709\u7684\u8840\u7ba1\u6700\u5167\u5c64\u90fd\u662f\u7531\u4e00\u5c64\u5167\u76ae\u7d30\u80de\u6240\u8986\u84cb\uff0c\u8840\u7ba1\u5167\u6240\u6709\u7684\u7269\u8cea\u901a\u900f\u90fd\u9700\u8981\u4ef0\u4ed7\u5167\u76ae\u7d30\u80de\u3002\u4eba\u9ad4\u5167\u7d04\u670910\u768413\u6b21\u65b9\u500b\u5167\u76ae\u7d30\u80de\uff0c\u7e3d\u91cd\u91cf\u7d04\u70ba\u4e00\u516c\u65a4\uff0c\u5c6c\u65bc\u6392\u540d\u524d\u5e7e\u5927\u7684\u5668\u5b98\u3002<\/p>\n<p>\u6211\u5011\u53ef\u4ee5\u5229\u7528\u5167\u76ae\u7d30\u80de\u9032\u884c\u8840\u7ba1\u751f\u6210\u7684\u76f8\u95dc\u7814\u7a76\u3002\u7814\u7a76\u4e2d\u5167\u76ae\u7d30\u80de\u7684\u4e09\u5927\u4e3b\u8981\u4f86\u6e90\uff0c\u5206\u5225\u662f\u4eba\u985e\u7684\u81cd\u5e36\u3001\u725b\u7684\u5927\u52d5\u8108\u53ca\u8001\u9f20\u7684\u52d5\u8108\uff0c\u53d6\u5f97\u5167\u76ae\u7d30\u80de\u4ee5\u5f8c\uff0c\u6211\u5011\u53ef\u4ee5\u5c07\u5167\u76ae\u7d30\u80de\u57f9\u990a\u5728\u57fa\u8cea\u4e2d\uff0c\u9069\u7576\u7684\u7d66\u4e88\u523a\u6fc0\uff0c\u5982\u679c\u53d7\u5230\u523a\u6fc0\u7684\u8a71\uff0c\u5167\u76ae\u7d30\u80de\u6703\u5f62\u6210\u7ba1\u72c0\u7d50\u69cb\uff0c\u9032\u800c\u85c9\u7531\u89c0\u5bdf\u5167\u76ae\u7d30\u80de\u7684\u53cd\u61c9\u5f97\u5230\u5be6\u9a57\u6578\u64da\u53ca\u7d50\u8ad6\u3002<\/p>\n<p>\u8209\u4f8b\u4f86\u8aaa\uff0c\u5927\u90e8\u5206\u7684\u514d\u75ab\u53cd\u61c9\u90fd\u662f\u56e0\u70ba\u8840\u7403\u7d30\u80de\u5728\u7d44\u7e54\u53d7\u5230\u5f71\u97ff\u6642\uff0c\u8840\u7403\u5167\u7684\u767d\u8840\u7403\u6703\u7a7f\u51fa\u5167\u76ae\u7d30\u80de\u7684\u969c\u7919\u8dd1\u5230\u7d44\u7e54\u5167\uff0c\u628a\u5916\u4f86\u7269\u7d66\u6d88\u6ec5\uff0c\u6211\u5011\u53ef\u4ee5\u5229\u7528\u514d\u75ab\u7d30\u80de\u7684\u6b64\u9805\u6a5f\u5236\u4f86\u505a\u7814\u7a76\u3002\u57f9\u990a\u55ae\u5c64\u5167\u76ae\u7d30\u80de\u7d66\u4e88\u5404\u7a2e\u4e0d\u540c\u7684\u8655\u7406\uff0c\u7d93\u904e\u523a\u6fc0\u5f8c\u89c0\u5bdf\u4e0a\u65b9\u79fb\u884c\u5230\u5167\u76ae\u7d30\u80de\u5c64\u4e0b\u65b9\u7684\u514d\u75ab\u7d30\u80de\u6216\u767d\u8840\u7403\u6709\u7121\u8b8a\u5316\u3002<\/p>\n<p>\u6211\u5011\u5982\u4f55\u6e2c\u5b9a\u5167\u76ae\u7d30\u80de\u6709\u7121\u88ab\u523a\u6fc0\u5462\uff1f\u6700\u7c21\u55ae\u7684\u65b9\u6cd5\u5c31\u662f\u300c\u76f4\u63a5\u6578\u7d30\u80de\u300d\uff0c\u6211\u5011\u5c07\u5f85\u5074\u7269\u8cea\u653e\u5165\u7d30\u80de\u4e2d\uff0c\u89c0\u5bdf\u6709\u8655\u7406\u904e\u7684\u8207\u6c92\u6709\u8655\u7406\u904e\u7684\u7d30\u80de\u6578\u76ee\u6709\u7121\u589e\u6e1b\u3002\u7b2c\u4e8c\u500b\u662f\u300c\u6a19\u5b9aDNA\u300d\uff0c\u7d30\u80de\u6709\u4e00\u5b9a\u542b\u91cf\u7684 DNA\uff0c\u800c\u7d30\u80de\u6578\u91cf\u8207 DNA \u542b\u91cf\u6210\u6b63\u6bd4\uff0c\u56e0\u6b64\u6211\u5011\u53ef\u85c9\u7531\u6e2c\u5b9a\u7d30\u80de\u88e1\u9762\u7684 DNA \u542b\u91cf\u5f97\u77e5\u7d30\u80de\u662f\u5426\u88ab\u523a\u6fc0\u3002\u7b2c\u4e09\u7a2e\u5e38\u898b\u7684\u65b9\u6cd5\u5247\u662f\u300c\u6e2c\u91cf\u7d30\u80de\u4ee3\u8b1d\u80fd\u529b\u300d\uff0c\u7576\u7d30\u80de\u8d8a\u4f86\u8d8a\u591a\u6642\uff0c\u7522\u751f\u7684\u4ee3\u8b1d\u7522\u7269\u4e5f\u6703\u96a8\u4e4b\u589e\u52a0\uff0c\u56e0\u6b64\u91cf\u6e2c\u7d30\u80de\u7684\u4ee3\u8b1d\u7269\u5c31\u53ef\u5f97\u77e5\u5167\u76ae\u7d30\u80de\u6709\u7121\u88ab\u523a\u6fc0\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u764c\u75c7\uff08Cancer\uff09<\/strong><\/span><\/p>\n<p>\u826f\u6027\u816b\u7624\u8207\u8207\u60e1\u6027\u816b\u7624\u6700\u5927\u7684\u5dee\u7570\uff0c\u5728\u65bc\u816b\u7624\u6709\u7121\u7a7f\u904e\u57fa\u5e95\u819c\u3002\u4eba\u9ad4\u5167\u6240\u6709\u7684\u67d3\u8272\u9ad4\u90fd\u662f\u6210\u96d9\u6210\u5c0d\u7684\uff0c\u7576\u4e00\u7d44\u7684\u81f4\u764c\u57fa\u56e0\u4e2d\u53ea\u8981\u6709\u4e00\u500b\u7522\u751f\u7a81\u8b8a\uff0c\u5c31\u6709\u6a5f\u6703\u8b8a\u6210\u764c\u7d30\u80de\u3002 DNA \u8907\u88fd\u7684\u904e\u7a0b\u5e38\u6703\u7522\u751f DNA \u7a81\u8b8a\uff0c\u5047\u5982\u67d3\u8272\u9ad4\u6c92\u6709\u8907\u88fd\u5b8c\u5168\u5c31\u5206\u88c2\u958b\u4f86\uff0c\u6703\u4f7f\u67d3\u8272\u9ad4\u8868\u73fe\u7570\u5e38\u3002\u70ba\u907f\u514d\u7570\u5e38\u767c\u751f\uff0c\u7d30\u80de\u88e1\u7684\u816b\u7624\u6291\u5236\u57fa\u56e0\u6703\u6aa2\u67e5\u67d3\u8272\u9ad4\u662f\u5426\u6709\u8907\u88fd\u5b8c\u5168\uff0c\u8b93\u7d30\u80de\u4e0d\u8981\u764c\u5316\u3002\u816b\u7624\u6291\u5236\u57fa\u56e0\u5982\u540c\u4eba\u9ad4\u5167\u7684\u4fdd\u885b\u5175\uff0c\u4e5f\u56e0\u70ba\u4eba\u9ad4\u5167\u7684\u67d3\u8272\u9ad4\u662f\u6210\u96d9\u6210\u5c0d\u7684\uff0c\u6240\u4ee5\u7576\u4e00\u500b\u885b\u5175\uff08\u816b\u7624\u6291\u5236\u57fa\u56e0\uff09\u9663\u4ea1\u6642\uff0c\u9084\u6709\u4e00\u500b\u885b\u5175\uff08\u816b\u7624\u6291\u5236\u57fa\u56e0\uff09\u53ef\u4ee5\u7e7c\u7e8c\u7ad9\u5d17\uff0c\u76f4\u5230\u5169\u500b\u885b\u5175\uff08\u816b\u7624\u6291\u5236\u57fa\u56e0\uff09\u90fd\u5012\u4e0b\u6642\u624d\u6703\u5f62\u6210\u816b\u7624\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u764c\u7d30\u80de\u8f49\u79fb\uff08Metastasis\uff09<\/strong><\/span><\/p>\n<p>\u764c\u7d30\u80de\u7522\u751f\u8840\u7ba1\u5f8c\uff0c\u85c9\u7531\u8840\u7ba1\u9032\u5165\u9ad4\u5167\u5404\u500b\u4e0d\u540c\u7d44\u7e54\u5340\u57df\u7a31\u70ba\u764c\u75c7\u8f49\u79fb\u3002\u4eba\u9ad4\u5167\u7d30\u80de\u5927\u5c0f\u7684\u4e0a\u9650\u662f\u53d7\u5230\u64f4\u6563\u4f5c\u7528\u7684\u9650\u5236\uff0c\u56e0\u70ba\u7d30\u80de\u9700\u8981\u4f9d\u8cf4\u64f4\u6563\u4f5c\u7528\u9032\u884c\u4ea4\u63db\u7269\u8cea\uff0c\u64f4\u6563\u4f5c\u7528\u53c8\u8207\u8868\u9762\u7a4d\u6210\u6b63\u6bd4\uff0c\u6240\u4ee5\u7576\u7d30\u80de\u904e\u5927\u6216\u904e\u7c97\u6642\u8868\u9762\u7a4d\u53cd\u800c\u6703\u8b8a\u5c0f\uff0c\u9019\u4e5f\u662f\u70ba\u4ec0\u9ebc\u54fa\u4e73\u985e\u7684\u7d30\u80de\u7684\u5927\u5c0f\u7686\u7dad\u6301\u572810-100\u03bcm\u3002\u6240\u4ee5\u7576\u7d30\u80de\u8b8a\u5927\u6642\u8868\u9762\u7a4d\u6703\u6108\u4f86\u8d8a\u5c0f\uff0c\u7d30\u80de\u7121\u6cd5\u9032\u884c\u7269\u8cea\u4ea4\u63db\uff0c\u7406\u8ad6\u4e0a\u816b\u7624\u4e0d\u61c9\u8a72\u5b58\u5728\uff0c\u82f1\u570b\u5916\u79d1\u91ab\u5e2b Judah Folkman \u4e5f\u66fe\u5c0d\u9019\u500b\u554f\u984c\u611f\u5230\u7591\u60d1\uff0c\u900f\u904e\u4ee5\u4e0b\u7684\u5be6\u9a57\u624d\u5f97\u77e5\u816b\u7624\u662f\u5982\u4f55\u7a81\u7834\u9650\u5236\u7684\u3002<\/p>\n<p>\u9996\u5148\uff0cJudah Folkman \u5c07\u816b\u7624\u7d44\u7e54\u5207\u788e\u5f8c\u653e\u5165\u57f9\u990a\u57fa\u4e2d\u7d66\u4e88\u7121\u9650\u7684\u990a\u5206\uff0c\u7121\u8ad6\u5982\u4f55\uff0cJudah Folkman \u7528\u57f9\u990a\u57fa\u57f9\u990a\u51fa\u7684\u816b\u7624\u7d44\u7e54\u90fd\u4e0d\u6703\u8d85\u904e 1mm\uff0c\u65bc\u662f\u4ed6\u53c8\u5c07\u816b\u7624\u7d44\u7e54\u653e\u5165\u5230\u6c92\u6709\u8840\u7ba1\u7684\u8001\u9f20\u89d2\u819c\u4e2d\u751f\u9577\uff0c\u767c\u73fe\u816b\u7624\u4f9d\u7136\u6c92\u6709\u9577\u5927\uff0c\u63a5\u8457\u518d\u628a\u816b\u7624\u7d44\u7e54\u653e\u5165\u5bcc\u6709\u8840\u7ba1\u7d44\u7e54\u7684\u8001\u9f20\u8679\u819c\u4e2d\uff0c\u50c5\u50c512\u5929\u7684\u6642\u9593\uff0c\u816b\u7624\u751f\u9577\u5927\u5230\u5a01\u8105\u8001\u9f20\u7684\u751f\u547d\uff0c\u540c\u6a23\u7684\u5c07\u816b\u7624\u7f6e\u65bc\u5be6\u9a57\u52d5\u7269\u76ae\u4e0b\uff0c\u816b\u7624\u4e5f\u6703\u7522\u751f\u8840\u7ba1\u5feb\u901f\u589e\u9577\u3002<\/p>\n<p>\u85c9\u7531\u9019\u5e7e\u500b\u5be6\u9a57\u5f97\u77e5\uff0c\u816b\u7624\u7d30\u80de\u70ba\u4e86\u7a81\u7834\u8868\u9762\u7a4d\u7684\u9650\u5236\uff0c\u6703\u8b93\u5bbf\u4e3b\u7684\u8840\u7ba1\u751f\u9577\u9032\u816b\u7624\u7d30\u80de\u5167\u5f97\u4ee5\u4e0d\u9593\u65b7\u7684\u751f\u9577\u3002\u56e0\u6b64\u7522\u751f\u816b\u7624\u4e00\u5b9a\u9700\u8981\u8840\u7ba1\u7684\u751f\u6210\uff0c\u5982\u679c\u6211\u5011\u80fd\u5920\u627e\u5230\u6291\u5236\u8840\u7ba1\u751f\u6210\u7684\u6a5f\u5236\uff0c\u5c31\u53ef\u4ee5\u6709\u6548\u5730\u63a7\u5236\u764c\u75c7\u7684\u751f\u6210\uff0c\u5c0d\u65bc\u4eba\u985e\u7684\u91ab\u5b78\u767c\u5c55\u4f86\u8aaa\u662f\u4e00\u5927\u798f\u7949\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u6291\u5236\u8840\u7ba1\u751f\u6210\u4e4b\u56e0\u5b50\uff08Anti-and pro-angiogenic factor\uff09<\/strong><\/span><\/p>\n<p>\u8840\u7ba1\u751f\u6210\u540c\u6642\u53d7\u5230\u523a\u6fc0\u53ca\u6291\u5236\u7269\u8cea\u7684\u8abf\u63a7\uff0c\u53ef\u7d93\u7531\u5be6\u9a57\u6e2c\u8a66\u904e\u7a0b\u5f97\u77e5\u5f85\u5074\u7269\u8cea\u8207\u8840\u7ba1\u751f\u6210\u662f\u5426\u6709\u76f4\u63a5\u7684\u95dc\u4fc2\u3002\u7d93\u904e\u9577\u671f\u7684\u7814\u7a76\uff0c\u5df2\u7d93\u6709\u8a31\u591a\u7269\u8cea\u88ab\u767c\u73fe\u5177\u6709\u523a\u6fc0\u8840\u7ba1\u751f\u6210\u7684\u80fd\u529b\uff0c\u5176\u4e2d\u6700\u91cd\u8981\u8207\u764c\u75c7\u7d30\u80de\u751f\u6210\u6709\u95dc\u7684\u5206\u5b50\u5373\u662f VEGF\uff08Vascular endothelial group factor\uff09\uff0c\u4ea6\u6709\u591a\u7a2e\u7269\u8cea\u88ab\u767c\u73fe\u5177\u6709\u6291\u5236\u8840\u7ba1\u751f\u6210\u7684\u80fd\u529b\u3002<\/p>\n<p>\u764c\u7d30\u80de\u6703\u7522\u751f\u5167\u76ae\u7d30\u80de\u751f\u9577\u56e0\u5b50 EGF \u523a\u6fc0\u8840\u7ba1\u751f\u6210\uff0c\u7576\u751f\u9577\u56e0\u5b50\u8dd1\u5230\u8840\u7ba1\u65c1\u908a\u6642\uff0c\u6703\u8207\u5167\u76ae\u7d30\u80de\u4e0a\u7684\u63a5\u53d7\u5668\u7d50\u5408\u6d3b\u5316\uff0c\u88ab\u6d3b\u5316\u7684\u5167\u76ae\u7d30\u80de\u6703\u91cb\u653e\u51fa\u53ef\u5207\u9664\u5468\u570d\u57fa\u8cea\u7684\u6c34\u89e3\u9175\u7d20\uff0c\u8b93\u8840\u7ba1\u6709\u589e\u9577\u7684\u7a7a\u9593\uff0c\u7d93\u904e\u5206\u88c2\u53ca\u79fb\u884c\u4f5c\u7528\u5f8c\u7522\u751f\u8840\u7ba1\u3002\u5728\u9019\u4e9b\u904e\u7a0b\u4e2d\uff0c\u53ea\u8981\u80fd\u5920\u6709\u6548\u6291\u5236\u5176\u4e2d\u4e00\u500b\u5730\u65b9\uff0c\u5373\u53ef\u8a2d\u8a08\u51fa\u963b\u65b7\u8840\u7ba1\u751f\u6210\u7684\u85e5\u7269\u3002<\/p>\n<p>VEGF \u6297\u9ad4\u662f\u6700\u65e9\u901a\u904e\u7f8e\u570b\u98df\u54c1\u85e5\u7269\u6aa2\u9a57\u5c40\u4e4b\u9a57\u8b49\u7684\u6297\u8840\u7ba1\u751f\u6210\u85e5\u7269\uff0c\u5c0d\u65bc\u816b\u7624\u7684\u6291\u5236\u4e0d\u518d\u53ea\u662f\u7a7a\u8ac7\uff0c\u800c\u662f\u53ef\u4ee5\u6709\u5be6\u969b\u7684\u4f5c\u70ba\uff0c\u5c31\u8b93\u6211\u5011\u76e1\u60c5\u53bb\u63a2\u7d22\u5427\uff01<\/p>\n<p><strong>--<\/strong><br \/>\n<strong>\u672c\u6587\u6574\u7406\u81ea\uff1a105\/11\/19 \u7531\u674e\u5fc3\u4e88\u6559\u6388\u5728\u81fa\u5927\u601d\u4eae\u9928\u570b\u969b\u6703\u8b70\u5ef3\u6240\u4e3b\u8b1b\u4e4b\u300c<a href=\"https:\/\/www.youtube.com\/watch?v=ez-8mi3Pf5w&amp;index=16&amp;list=PLil-R4o6jmGhORJTP4LopEozH1LqDUrxK\" target=\"_blank\">\u8840\u7ba1\u7684\u751f\u6210\uff1a\u591a\u7d30\u80de\u751f\u7269\u9ad4\u5167\u9ad8\u901f\u516c\u8def\u7684\u69cb\u7bc9\u904e\u7a0b<\/a>\u300d\u6f14\u8b1b\u5167\u5bb9\u3002<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u672c\u5834\u6f14\u8b1b\u95dc\u9375\u5b57\u8a5e\uff0c\u5206\u5225\u662f\u8840\u7ba1\u751f\u6210\uff08Angiogenesis\uff09\u3001\u5167\u76ae\u7d30\u80de\uff08Endothelial cell\uff09\u3001\u764c\u75c7\uff08Cancer\uff09\u3001\u764c\u7d30\u80de\u8f49\u79fb\uff08Metastasis\uff09\u548c\u4fc3\u8840\u7ba1\u751f\u6210\u4ee5\u53ca\u6291\u5236\u8840\u7ba1\u751f\u6210\u4e4b\u56e0\u5b50\uff08Anti-and pro-angiogenic factor\uff09\u3002\u900f\u904e\u5be6\u969b\u7684\u4f8b\u5b50\u3001\u6709\u8da3\u7684\u4ecb\u7d39\u4ee5\u53ca\u89aa\u8eab\u7d93\u9a57\uff0c\u8b93\u6211\u5011\u5728\u6f14\u8b1b\u7684\u904e\u7a0b\u4e2d\u5c0d\u8840\u7ba1\u751f\u6210\u7684\u6a5f\u5236\u6709\u66f4\u591a\u7684\u8a8d\u8b58\u3002<\/p>\n","protected":false},"author":20,"featured_media":26324,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,2861],"tags":[3029,2968,378,3030,3027,3028],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/12\/16-6-Artery.jpeg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/26323"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26323"}],"version-history":[{"count":5,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/26323\/revisions"}],"predecessor-version":[{"id":32721,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/26323\/revisions\/32721"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/26324"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26323"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26323"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26323"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}