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\u53bb\u5e74\uff0c\u5df4\u897f\u91ab\u7642\u7814\u7a76\u6a5f\u69cbEvandro Chagas Institute\u5728\u5883\u5167\u75ab\u60c5\u56b4\u91cd\u5730\u5340\u4e4b\u4e00\u7684\u6771\u5317\u65b9\uff0c\u5206\u96e2\u51fa\u75c5\u6bd2\u682a\uff0c\u6b63\u597d\u9069\u5408\u62ff\u4f86\u505a\u7814\u7a76\u3002\u4f46\u56e0\u70ba\u795e\u7d93\u7cfb\u7d71\u7f3a\u9677\u53ea\u5728\u9019\u6ce2\u75ab\u60c5\u88e1\u51fa\u73fe\uff0c\u4ee5\u524d\u90fd\u6c92\u6709\u76f8\u95dc\u6848\u4f8b\uff0c\u70ba\u4e86\u78ba\u8a8d\u5c0e\u81f4\u9019\u6b21\u75ab\u60c5\u7684\u75c5\u6bd2\u8207\u65b0\u751f\u5152\u5c0f\u982d\u7578\u5f62\u4e4b\u9593\u7684\u95dc\u9023\uff0c\u5be6\u9a57\u63a7\u5236\u7d44\u7684\u75c5\u6bd2\u682a\u9078\u64c7\uff0c\u5c31\u56e0\u800c\u8b8a\u5f97\u6975\u70ba\u95dc\u9375\u3002\u63a7\u5236\u7d44\u75c5\u6bd2\u682a\u8a72\u5982\u4f55\u6c7a\u5b9a\u5462\uff1f\u7814\u7a76\u4eba\u54e1\u9078\u7528\u4e861947\u5e74\uff0c\u7531\u8332\u5361\u68ee\u6797\u6046\u6cb3\u7334\u8840\u6db2\u6aa2\u9ad4\u6240\u5206\u96e2\u51fa\u4f86\u7684\u75c5\u6bd2\u682a\u3002\u9019\u682a\u6700\u65e9\u88ab\u767c\u73fe\u7684\u8332\u5361\u75c5\u6bd2\uff0c\u4ee5\u7334\u5b50\u70ba\u4e3b\u8981\u5bc4\u4e3b\uff0c\u8ddf\u73fe\u4eca\u6d41\u7ac4\u53ef\u4ee5\u4eba\u50b3\u4eba\u3001\u5728\u6f14\u5316\u4e0a\u300c\u9032\u5316\u300d\u904e\u7684\u8332\u5361\u75c5\u6bd2\u5f88\u4e0d\u4e00\u6a23\u3002\u7814\u7a76\u4eba\u54e1\u9084\u540c\u6642\u7528\u4e86\u53e6\u4e00\u682a\u88ab\u7528\u4f86\u88fd\u9020\u9ec3\u71b1\u75c5\u75ab\u82d7\u7684\u75c5\u6bd2\u682a\u300cYFV-17D\u300d\u4e00\u8d77\u4f5c\u70ba\u63a7\u5236\u7d44\u3002YFV-17D\u75c5\u6bd2\u8ddf\u8332\u5361\u75c5\u6bd2\u540c\u5c6c\u65bc\u9ec3\u8cea\u75c5\u6bd2\u5c6c\uff0c\u800c\u4e14\u5df2\u7d93\u8b49\u5be6YFV-17D\u9ec3\u71b1\u75c5\u75ab\u82d7\u682a\u5f15\u8d77\u7684\u6297\u9ad4\u53cd\u61c9\uff0c\u7121\u6cd5\u91dd\u5c0d\u8332\u5361\u75c5\u6bd2\u63d0\u4f9b\u4fdd\u8b77\u4f5c\u7528\uff0c\u986f\u793a\u9019\u5169\u500b\u4e0d\u540c\u7684\u75c5\u6bd2\u682a\u5728\u672c\u8cea\u4e0a\u4e26\u4e0d\u76f8\u540c\u3002\u63a5\u4e0b\u4f86\uff0c\u7814\u7a76\u4eba\u54e1\u628a\u9019\u4e09\u682a\u8332\u5361\u75c5\u6bd2\u5206\u5225\u62ff\u53bb\u611f\u67d3\u61f7\u5b55\u7684\u7d14\u54c1\u7cfb\u96cc\u6027\u5c0f\u9f20\u300cSJL\u300d\u8207\u300cC57BL\/6\u300d\uff0c\u4e26\u5728\u65b0\u751f\u5c0f\u9f20\u4e00\u843d\u5730\u5f8c\uff0c\u5c31\u6aa2\u6e2c\u795e\u7d93\u7cfb\u7d71\u767c\u80b2\u72c0\u6cc1\u3002<\/p>\n

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\u539f\u59cb\u8ad6\u6587\uff1a<\/strong>Cugola FR et al. The Brazilian Zika virus strain causes birth defects in experimental models. Nature. 2016 May 11;534(7606):267-71. doi: 10.1038\/nature18296.<\/p>\n

\u53c3\u8003\u8cc7\u6599\uff1a\u00a0<\/strong><\/p>\n

    \n
  1. Faria, N. R. et al. Zika virus in the Americas: early epidemiological and genetic findings. Science 352, 345\u2013349 (2016)<\/li>\n
  2. Cao-Lormeau, V. M. et al. Guillain-Barr\u00e9 Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet 387, 1531\u20131539 (2016)<\/li>\n
  3. Rasmussen, S. A., Jamieson, D. J., Honein, M. A. & Petersen, L. R. Zika virus and birth defects - reviewing the evidence for causality. N. Engl. J. Med<\/li>\n<\/ol>\n

    --<\/span><\/strong>
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     <\/p>\n

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