{"id":24707,"date":"2016-06-30T00:57:36","date_gmt":"2016-06-29T16:57:36","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=24707"},"modified":"2018-07-13T00:18:17","modified_gmt":"2018-07-12T16:18:17","slug":"%e3%80%90%e9%80%b1%e5%9b%9b%e6%a4%8d%e7%89%a9%e7%a7%80%e3%80%91%e6%a4%8d%e7%89%a9%e7%9a%84%e8%a8%98%e6%86%b6%e8%88%87%e6%99%ae%e5%88%a9%e6%98%82%e8%9b%8b%e7%99%bd","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=24707","title":{"rendered":"\u690d\u7269\u7684\u8a18\u61b6\u8207\u666e\u5229\u6602\u86cb\u767d"},"content":{"rendered":"<figure id=\"attachment_24708\" aria-describedby=\"caption-attachment-24708\" style=\"width: 330px\" class=\"wp-caption alignleft\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-24708\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/05\/330px-Flower_poster_2.jpg\" alt=\"\u5716\u7247\u4f86\u6e90\uff1awiki\" width=\"330\" height=\"439\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/05\/330px-Flower_poster_2.jpg 330w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/05\/330px-Flower_poster_2-225x300.jpg 225w\" sizes=\"(max-width: 330px) 100vw, 330px\" \/><figcaption id=\"caption-attachment-24708\" class=\"wp-caption-text\">\u5716\u7247\u4f86\u6e90\uff1awiki<\/figcaption><\/figure>\n<p><strong>\u64b0\u6587\uff5c<\/strong>\u8449\u7da0\u8212<\/p>\n<p>\u63d0\u5230\u666e\u5229\u6602\u86cb\u767d\uff08prion\uff09\uff0c\u5927\u5bb6\u7b2c\u4e00\u500b\u60f3\u5230\u7684\u5c31\u662f\u72c2\u725b\u75c7\u3002\u7531\u65bc\u5b83\u5011\u57281982\u5e74\u88ab\u767c\u73fe\u6703\u5c0e\u81f4\u5c0e\u81f4\u300c\u72c2\u725b\u75c7\u300d\u8207\u7f8a\u7684\u6414\u7662\u75c7\uff08Scrapie\uff09\uff0c\u4f7f\u5f97\u5927\u5bb6\u805e\u666e\u5229\u6602\u86cb\u767d\u800c\u8272\u8b8a\u3002\u4f46\u662f\uff0c\u666e\u5229\u6602\u86cb\u767d\u4e26\u4e0d\u90fd\u662f\u58de\u7684\u5594\uff01\u7531\u65bc\u666e\u5229\u6602\u86cb\u767d\u6703\u81ea\u884c\u8907\u88fd\uff0c\u4f7f\u5f97\u5b83\u5f88\u9069\u5408\u4f5c\u70ba\u4ee3\u4ee3\u76f8\u50b3\u7684\u5206\u5b50\u3002\u6709\u597d\u4e9b\u8f49\u9304\u6216\u8f49\u8b6f\u8abf\u7bc0\u86cb\u767d\u4ee5\u53caRNA\u52a0\u5de5\u86cb\u767d\u90fd\u6709\u666e\u5229\u6602\u86cb\u767d\u7684\u7d50\u69cb\u57df\uff08prion 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#008080;\"><strong>\u25cf\u690d\u7269\u5982\u4f55\u8a18\u61b6\u300c\u5c0d\u7684\u300d\u5149\u9031\u671f\uff1f<\/strong><\/span><\/p>\n<p>\u8a31\u591a\u690d\u7269\u9700\u8981\u300c\u5c0d\u7684\u300d\u5149\u9031\u671f\u6301\u7e8c\u4e00\u6bb5\u6642\u9593\u5f8c\u624d\u80fd\u5553\u52d5\u958b\u82b1\u7a0b\u5e8f\u3002\u4f46\u662f\uff0c\u6709\u4e9b\u690d\u7269\u53ea\u9700\u8981\u66b4\u9732\u5728\u300c\u5c0d\u7684\u300d\u5149\u9031\u671f\u4e00\u5169\u5929\uff0c\u6709\u4e9b\u690d\u7269\u5247\u9700\u8981\u4e00\u5169\u9031\u6216\u751a\u81f3\u4e00\u500b\u6708\u90fd\u662f\u300c\u5c0d\u7684\u300d\u5149\u9031\u671f\uff0c\u624d\u80fd\u555f\u52d5\u958b\u82b1\u7a0b\u5e8f\u3002\u7a76\u7adf\u690d\u7269\u662f\u5982\u4f55\u8a18\u5f97\u90a3\u300c\u5c0d\u7684\u300d\u5149\u9031\u671f\u6301\u7e8c\u591a\u4e45\u4e86\u5462\uff1f\u800c\u5b83\u5011\u53c8\u80fd\u8a18\u5f97\u9019\u500b\u8cc7\u8a0a\u591a\u4e45\u5462\uff1f\u4e0d\u77e5\u9053\u3002\u76ee\u524d\u7684\u7d00\u9304\u4fdd\u6301\u4eba\u662f\u51ac\u5c0f\u9ea5\uff1a\u79d1\u5b78\u5bb6\u5011\u628a\u7d93\u904e\u51b7\u8655\u7406\u5f8c\u7684\u51ac\u5c0f\u9ea5\u9032\u884c\u7d44\u7e54\u57f9\u990a\uff0c\u9577\u51fa\u7684\u7652\u50b7\u7d44\u7e54\uff08callus\uff09\u5728\u57f9\u990a\u70ba\u6210\u682a\u5f8c\uff0c\u5b8c\u5168\u4e0d\u9700\u8981\u6625\u5316\u8655\u7406\uff08vernalization\uff09\uff0c\u4fbf\u80fd\u5728\u7b2c\u4e00\u500b\u6625\u5929\u5c31\u958b\u82b1\u7d50\u679c\u3002\u9019\u9ebc\u597d\u7684\u8a18\u61b6\uff0c\u7a76\u7adf\u662f\u5f9e\u54ea\u88e1\u4f86\u7684\uff1f<!--more--><\/p>\n<p>\u6700\u8fd1\u7684\u7814\u7a76\u767c\u73fe\uff0c\u690d\u7269\u6216\u8a31\u4e5f\u662f\u900f\u904e\u5177\u6709\u985e\u4f3c\u666e\u5229\u6602\u86cb\u767d\u8cea\u7d50\u69cb\u57df\u7684\u86cb\u767d\u8cea\uff0c\u628a\u9019\u4e9b\u8cc7\u8a0a\u7d00\u9304\u5728\u690d\u7269\u7d30\u80de\u4e2d\u3002<\/p>\n<p>\u7531\u65bc\u690d\u7269\u5c0d\u5149\u9031\u671f\u7684\u300c\u8a18\u61b6\u300d\u8d85\u5353\uff0c\u56e0\u6b64\u4f86\u81ea\u9ebb\u7701\u7406\u5de5\u5b78\u9662\u7684\u7814\u7a76\u5718\u968a\uff0c\u5617\u8a66\u8457\u5728\u64ec\u5357\u82a5\u7684\u57fa\u56e0\u9ad4\u5167\u5c0b\u627e\u666e\u5229\u6602\u86cb\u767d\u7684\u86cb\u767d\u8cea\u7d50\u69cb\u57df\u3002\u641c\u5c0b\u7684\u7d50\u679c\u4e00\u5171\u627e\u5230475\u500b\u542b\u6709\u666e\u5229\u6602\u86cb\u767d\u7d50\u69cb\u57df\u7684\u57fa\u56e0\uff1a\u9019\u4e9b\u57fa\u56e0\u5305\u62ec\u4e86\u8f49\u9304\u8abf\u7bc0\u86cb\u767d\u3001RNA\u9023\u7d50\u86cb\u767d\u3001\u8207RNA\u4ee3\u8b1d\u76f8\u95dc\u7684\u86cb\u767d\u3001\u8207\u7e41\u6b96\u53ca\u767c\u80b2\u76f8\u95dc\u7684\u86cb\u767d\u9084\u6709\u82b1\u6735\u767c\u80b2\u76f8\u95dc\u7684\u86cb\u767d\u3002\u5176\u4e2d\uff0c\u7814\u7a76\u5718\u968a\u6311\u9078\u4e86LD\uff08Luminidependens\uff09\u3001FPA\uff08Flowering Locus PA\uff09\u3001FCA\uff08Flowering Locus CA\uff09\u8207FY\uff08Flowering Locus Y\uff09\u9019\u56db\u500b\u5e36\u6709\u666e\u5229\u6602\u86cb\u767d\u8cea\u7d50\u69cb\u57df\u7684\u57fa\u56e0\u3002<\/p>\n<p><span style=\"color: #008080;\"><strong>\u25cf\u56db\u500b\u8207\u958b\u82b1\u76f8\u95dc\u7684\u666e\u5229\u6602\u86cb\u767d\u57fa\u56e0<\/strong><\/span><\/p>\n<p>\u6311\u9078\u9019\u56db\u500b\u57fa\u56e0\u4e3b\u8981\u7684\u539f\u56e0\uff0c\u662f\u56e0\u70ba\u5b83\u5011\u90fd\u8207\u958b\u82b1\u76f8\u95dc\u3002\u5176\u4e2dLD\u662f\u500b\u8f49\u9304\u8abf\u7bc0\u86cb\u767d\uff0c\u800cFPA\u8207FCA\u5247\u662fRNA\u9023\u7d50\u86cb\u767d\uff1b\u81f3\u65bcFY\u5247\u5c0d\u65bcRNA\u7684\u52a0\u5de5\uff08RNA processing\uff09\u6709\u95dc\u3002\u70ba\u4e86\u8981\u6e2c\u8a66\u5b83\u5011\u662f\u5426\u5177\u6709\u985e\u4f3c\u65bc\u666e\u5229\u6602\u86cb\u767d\u7684\u7279\u6027\uff0c\u7814\u7a76\u5718\u968a\u5c07\u9019\u56db\u500b\u86cb\u767d\u5728\u9175\u6bcd\u83cc\uff08<em>S. cerevisiae<\/em>\uff0c\u5564\u9152\u9175\u6bcd\uff09\u4e2d\u9032\u884c\u4e86\u4e00\u9023\u4e32\u7684\u6e2c\u8a66\u3002\u4e4b\u6240\u4ee5\u9078\u64c7\u5728\u9175\u6bcd\u83cc\u88e1\u9762\uff0c\u800c\u4e0d\u662f\u5728\u690d\u7269\u4e2d\u76f4\u63a5\u9032\u884c\uff0c\u662f\u56e0\u70ba\u76ee\u524d\uff08\u985e\uff09\u666e\u5229\u6602\u86cb\u767d\u5728\u690d\u7269\u4e2d\u7684\u529f\u80fd\u672a\u660e\uff0c\u56e0\u6b64\u8981\u6e2c\u8a66\u53ea\u80fd\u4ee5\u9175\u6bcd\u83cc\u4f86\u9032\u884c\u6e2c\u8a66\u3002<\/p>\n<p>\u5728\u591a\u5e74\u524d\uff0c\u79d1\u5b78\u5bb6\u5011\u4fbf\u767c\u73fe\uff0c\u9175\u6bcd\u83cc\u88e1\u9762\u6709\u500bSup35\u86cb\u767d\uff0c\u7576\u5b83\u5728\u4e00\u822c\u69cb\u5f62\u6642\uff0c\u5b83\u6703\u8b93\u4e00\u500b\u8207\u5408\u6210\u817a\u560c\u5464\u76f8\u95dc\u7684\u9175\u7d20ADE1\u7121\u6cd5\u7522\u751f\uff0c\u65bc\u662f\u9019\u500b\u9175\u6bcd\u83cc\u5c31\u4e00\u5b9a\u8981\u7d66\u817a\u560c\u5464\u624d\u80fd\u9577\uff1b\u800c\u7576\u5b83\u9ad8\u91cf\u8868\u73fe\u6642\uff0cSup35\u5c31\u6703\u5f62\u6210\u666e\u5229\u6602\u69cb\u5f62\uff0c\u9019\u9ebc\u4e00\u4f86ADE1\u86cb\u767d\u5c31\u53ef\u4ee5\u7522\u751f\uff0c\u7d50\u679c\u9175\u6bcd\u83cc\u5c31\u53ef\u4ee5\u5728\u4e0d\u542b\u817a\u560c\u5464\u7684\u57f9\u990a\u57fa\u4e0a\u9762\u751f\u9577\u4e86\u3002<\/p>\n<p>\u7528\u4e0a\u9762\u9019\u500b\u7cfb\u7d71\uff0c\u7814\u7a76\u5718\u968a\u5c07Sup35\u7684\u666e\u5229\u6602\u86cb\u767d\u8cea\u7d50\u69cb\u57df\u4ee5LD\u3001FPA\u3001FCA\u6216FY\u7684\u666e\u5229\u6602\u86cb\u767d\u8cea\u7d50\u69cb\u57df\u53d6\u800c\u4ee3\u4e4b\uff0c\u4e26\u9032\u884c\u4e00\u7cfb\u5217\u7684\u6e2c\u8a66\u3002\u6e2c\u8a66\u7d50\u679c\u767c\u73fe\uff0c\u5176\u4e2d\u7684LD\u86cb\u767d\uff0c\u5177\u5099\u6709\u6240\u6709\u5177\u6709\u666e\u5229\u6602\u86cb\u767d\u7684\u7279\u6027\uff1aLD\u7684\u666e\u5229\u6602\u86cb\u767d\u8cea\u7d50\u69cb\u57df\u5728\u904e\u91cf\u8868\u73fe\u7684\u72c0\u6cc1\u4e0b\uff0c\u53ef\u4ee5\u5f62\u6210\u985e\u4f3c\u666e\u5229\u6602\u86cb\u767d\u7684\u7d50\u69cb\uff0c\u7522\u751f\u6975\u70ba\u985e\u4f3c\u7684\u6548\u679c\u3002<\/p>\n<p>\u9019\u7814\u7a76\u6210\u679c\uff0c\u662f\u5426\u610f\u5473\u8457LD\u86cb\u767d\u5c31\u662f\u7d93\u7531\u5229\u7528\u5b83\u7684\u666e\u5229\u6602\u86cb\u767d\u8cea\u7d50\u69cb\u57df\u4f86\u8a18\u9304\u9019\u4e9b\u8cc7\u8a0a\uff0c\u9032\u800c\u5f71\u97ff\u690d\u7269\u7684\u767c\u80b2\u5462\uff1f\u800c\u5176\u4ed6\u4e09\u500b\u86cb\u767d\u8cea\uff0c\u662f\u5426\u4e5f\u6709\u985e\u4f3c\u7684\u529f\u80fd\u5462\uff1f\u9019\u4e9b\u90fd\u9084\u9700\u8981\u9032\u4e00\u6b65\u7684\u7814\u7a76\u3002\u4e0d\u904e\uff0c\u9019\u4e9b\u6210\u679c\u63d0\u4f9b\u4e86\u6211\u5011\u4e00\u500b\u65b0\u7684\u7814\u7a76\u8996\u89d2\uff0c\u771f\u7684\u662f\u975e\u5e38\u6709\u610f\u601d\u5462\uff01<\/p>\n<p><strong>\u53c3\u8003\u6587\u737b\uff1a<\/strong>Sohini Chakraborteea et. al. 2016.\u00a0<a href=\"http:\/\/www.pnas.org\/content\/early\/2016\/04\/20\/1604478113.abstract\">Luminidependens (LD) is an Arabidopsis protein with prion behavior<\/a>. PNAS.doi: 10.1073\/pnas.1604478113<\/p>\n<p><span style=\"color: #333399;\"><strong>--<\/strong><\/span><br style=\"color: #000000;\" \/><span style=\"color: #333399;\"><strong>\u4f5c\u8005\uff1a\u8449\u7da0\u8212\u3000\u6148\u6fdf\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb\u52a9\u7406\u6559\u6388\uff0c\u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b\uff0c\u5f9e\u4e8b\u79d1\u666e\u6587\u7ae0\u5beb\u4f5c\u3002<\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u64b0\u6587\uff5c\u8449\u7da0\u8212 \u63d0\u5230\u666e\u5229\u6602\u86cb\u767d\uff08prion<\/p>\n","protected":false},"author":20,"featured_media":24708,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,26,3100],"tags":[2597,2005,2596,2595,3099,1543,793],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/05\/330px-Flower_poster_2.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24707"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24707"}],"version-history":[{"count":4,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24707\/revisions"}],"predecessor-version":[{"id":31508,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24707\/revisions\/31508"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/24708"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24707"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24707"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24707"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}