{"id":24549,"date":"2016-06-01T00:11:14","date_gmt":"2016-05-31T16:11:14","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=24549"},"modified":"2018-08-03T14:45:09","modified_gmt":"2018-08-03T06:45:09","slug":"%e3%80%90%e5%af%b5%e7%89%a9%e5%b0%88%e6%ac%84%e3%80%91%e6%8b%89%e5%b8%83%e6%8b%89%e5%a4%9a%e7%8a%ac%e8%b2%aa%e5%90%83%e7%9a%84%e5%8e%9f%e5%9b%a0","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=24549","title":{"rendered":"\u3010\u5bf5\u7269\u5c08\u6b04\u3011\u62c9\u5e03\u62c9\u591a\u72ac\u8caa\u5403\u7684\u539f\u56e0"},"content":{"rendered":"<p><span style=\"color: #333399;\"><strong>\u25a0\u72d7\u5974\u5011\u90fd\u77e5\u9053\uff0c\u62c9\u5e03\u62c9\u591a\u72ac\u7121\u6642\u7121\u523b\u90fd\u5c0d\u98df\u7269\u611f\u8208\u8da3\u3002\u5c31\u56e0\u70ba\u8caa\u5403\uff0c\u6240\u4ee5\u62c9\u5e03\u62c9\u591a\u66f4\u5bb9\u6613\u7528\u98df\u7269\u7576\u734e\u52f5\u4f86\u8a13\u7df4\u3002\u62c9\u5e03\u62c9\u591a\u8caa\u5403\u6709\u751f\u7269\u5b78\u4e0a\u7684\u9053\u7406\u3002\u79d1\u5b78\u5bb6\u767c\u73fe\u4e00\u500b\u57fa\u56e0\u7684\u8b8a\u7570\u548c\u98df\u7269\u6fc0\u52f5\u7684\u884c\u70ba\u6709\u95dc\uff0c\u800c\u8a72\u57fa\u56e0\u8b8a\u7570\u5728\u62c9\u5e03\u62c9\u591a\u66f4\u5e38\u898b\u5230\u3002<\/strong><\/span><\/p>\n<figure id=\"attachment_24550\" aria-describedby=\"caption-attachment-24550\" style=\"width: 450px\" class=\"wp-caption alignleft\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-24550\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/05\/dog-1210559_960_720.jpg\" alt=\"CC0 Public Domain\" width=\"450\" height=\"338\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/05\/dog-1210559_960_720.jpg 960w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/05\/dog-1210559_960_720-300x225.jpg 300w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/05\/dog-1210559_960_720-600x450.jpg 600w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/05\/dog-1210559_960_720-800x600.jpg 800w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><figcaption id=\"caption-attachment-24550\" class=\"wp-caption-text\">CC0 Public Domain<\/figcaption><\/figure>\n<p><strong>\u64b0\u6587\uff5c<\/strong>\u9ec3\u8c9e\u7965<\/p>\n<p>\u56e0\u70ba\u62c9\u5e03\u62c9\u591a\u6bd4\u5176\u4ed6\u72d7\u66f4\u8caa\u5403\uff0c\u6240\u4ee5\u66f4\u5bb9\u6613\u8b8a\u80d6\u3002\u82f1\u570b\u528d\u6a4b\u5927\u5b78\u7684\u907a\u50b3\u5b78\u5bb6Eleanor Raffan\u7b49\u4eba\uff0c\u627e\u4e8615\u96bb\u80a5\u80d6\u548c18\u96bb\u82d7\u689d\u7684\u62c9\u5e03\u62c9\u591a\u3002\u4ed6\u5011\u6aa2\u9a57\u4e863\u500b\u548c\u4eba\u985e\u80a5\u80d6\u6709\u95dc\u7684\u57fa\u56e0\uff0c\u7d50\u679c\u767c\u73fe<em>POMC<\/em>\u57fa\u56e0\u7684\u8b8a\u7570\u8207\u62c9\u5e03\u62c9\u591a\u7684\u8caa\u5403\u53ef\u80fd\u6709\u95dc\u3002<\/p>\n<p>POMC\u57fa\u56e0\u80fd\u88fd\u9020\u524d\u8166\u5561\u9ed1\u7d30\u80de\u4fc3\u7d20\u76ae\u4fc3\u7d20\uff0c\u9019\u662f\u5f88\u591a\u6fc0\u7d20\u7684\u5171\u540c\u524d\u9a45\u7269\u8cea\u3002\u8a72\u62c9\u5e03\u62c9\u591a\u72ac\u7684\u907a\u50b3\u8b8a\u7570\u8b93\u57fa\u56e0\u5f8c\u982d\u88ab\u622a\u77ed\uff0c\u56e0\u6b64\u7121\u6cd5\u7522\u751f\u795e\u7d93\u80bd\u03b2-MSH\u548c\u03b2-\u5167\u5561\u80bd\uff0c\u5b83\u5011\u6703\u5728\u9910\u5f8c\u95dc\u9589\u9951\u9913\u611f\uff0c\u524d\u8005\u548c\u52d5\u7269\u89ba\u5bdf\u8102\u80aa\u7684\u5132\u5b58\u6709\u95dc\uff0c\u5f8c\u8005\u548c\u8166\u7684\u734e\u52f5\u8def\u5f91\u6709\u95dc\u3002POMC\u7684\u76f8\u4f3c\u57fa\u56e0\u8b8a\u7570\u548c\u4eba\u985e\u7684\u80a5\u80d6\u4e5f\u6709\u95dc\u3002<!--more--><\/p>\n<p>\u63a5\u8457\u4ed6\u5011\u627e\u4f86310\u96bb\u62c9\u5e03\u62c9\u591a\uff0c\u767c\u73fe\u4e26\u975e\u6240\u6709\u80a5\u80d6\u7684\u62c9\u5e03\u62c9\u591a\u90fd\u6709\u8a72\u57fa\u56e0\u8b8a\u7570\uff0c\u4e5f\u4e0d\u898b\u5f97\u6709\u4e86\u8a72\u57fa\u56e0\u8b8a\u7570\u5c31\u4e00\u5b9a\u6703\u8b8a\u80d6\uff0c\u4e0d\u904e\u6709\u4e86\u8a72\u57fa\u56e0\u8b8a\u7570\u7684\u62c9\u5e03\u62c9\u591a\u66f4\u5e38\u8ddf\u98fc\u4e3b\u4e5e\u8a0e\u98df\u7269\u3002\u5e73\u5747\u800c\u8a00\uff0c\u5e36\u67091\u4efd\u8a72\u57fa\u56e0\u8b8a\u7570\u7684\u96dc\u578b\u5408\u5b50\uff0c\u6703\u8b93\u72d7\u591a\u8fd12\u516c\u65a4\u9ad4\u91cd\uff0c\u800c\u5e36\u67092\u4efd\u7684\u540c\u578b\u5408\u5b50\uff0c\u6703\u8b93\u72d7\u591a\u8fd14\u516c\u65a4\u9ad4\u91cd\u3002\u5927\u6982\u670923%\u7684\u62c9\u4e0d\u62c9\u591a\u6709\u8a72POMC\u7684\u907a\u50b3\u8b8a\u7570\u3002<\/p>\n<p>\u79d1\u5b78\u5bb6\u5728\u82f1\u570b\u548c\u7f8e\u570b\u627e\u4e86\u53e6\u5916411\u96bb38\u500b\u54c1\u7cfb\u7684\u72d7\uff0c\u53ea\u6709\u5728\u548c\u62c9\u5e03\u62c9\u591a\u89aa\u7de3\u8f03\u8fd1\u7684\u5e73\u6bdb\u5c0b\u56de\u72ac\u6709\u627e\u5230\u8a72\u57fa\u56e0\uff0c\u7260\u5011\u4e5f\u662f\u540c\u6a23\u8caa\u5403\u3002\u7576\u4ed6\u5011\u8abf\u67e581\u96bb\u8a13\u7df4\u6709\u7d20\u7684\u62c9\u5e03\u62c9\u591a\u5354\u52a9\u72ac\uff0c76%\u7684\u72d7\u5e36\u6709\u8a72\u57fa\u56e0\u8b8a\u7570\u3002\u9019\u9ebc\u9ad8\u7684\u6bd4\u4f8b\uff0c\u6709\u53ef\u80fd\u662f\u56e0\u70ba\u8caa\u5403\u7684\u62c9\u5e03\u62c9\u591a\uff0c\u66f4\u5bb9\u6613\u7528\u98df\u7269\u7576\u734e\u52f5\u4f86\u8a13\u7df4\u3002<\/p>\n<p>\u4ed6\u5011\u8a8d\u70ba\u5728\u62c9\u5e03\u62c9\u591a\u627e\u5230\u548c\u4eba\u985e\u80a5\u80d6\u6709\u95dc\u7684\u57fa\u56e0\uff0c\u8aaa\u4e0d\u5b9a\u80fd\u7528\u72d7\u4f86\u7814\u7a76\u7642\u6cd5\uff0c\u56e0\u70ba\u904e\u53bb\u5e38\u7528\u4f86\u7814\u7a76\u80a5\u80d6\u7684\u5c0f\u9f20\u548c\u5927\u9f20\u7684POMC\u548c\u4eba\u985e\u7684\u5dee\u7570\u592a\u591a\u8f03\u4e0d\u9069\u7528\u3002<\/p>\n<p><strong>\u539f\u5b78\u8853\u8ad6\u6587\uff1a<\/strong>Raffan et al. A deletion in the canine POMC gene is associated with weight and appetite in obesity prone Labrador retriever dogs. Cell Metabolism, 2016 DOI: 10.1016\/j.cmet.2016.04.012<\/p>\n<p><strong>\u53c3\u8003\u8cc7\u6599\uff1a<\/strong><br \/>\n1. Cell Press. \"<a href=\"http:\/\/www.sciencedaily.com\/releases\/2016\/05\/160503130342.htm\" target=\"_blank\" rel=\"noopener noreferrer\">Why Labrador retrievers are more interested in food than other breeds<\/a>.\" ScienceDaily. ScienceDaily, 3 May 2016.<br \/>\n2. Nicola Davis. <a href=\"https:\/\/www.theguardian.com\/science\/2016\/may\/03\/labradors-could-be-genetically-hard-wired-for-greed\" target=\"_blank\" rel=\"noopener noreferrer\">Labradors may be genetically 'hard-wired' for greed<\/a>. The Guardian.\u00a03 May 2016.<br \/>\n3. Helen Briggs. <a href=\"http:\/\/www.bbc.com\/news\/science-environment-36170267\" target=\"_blank\" rel=\"noopener noreferrer\">Fat Labradors give clues to obesity epidemic.<\/a>\u00a0BBC News.\u00a03 May 2016.<\/p>\n<p><span style=\"color: #333399;\"><strong>--<\/strong><\/span><br style=\"color: #000000;\" \/><span style=\"color: #333399;\"><strong>\u4f5c\u8005\uff1a<strong>\u9ec3\u8c9e\u7965 \u73fe\u4efb\u6559\u65bc\u570b\u7acb\u6e05\u83ef\u5927\u5b78\u5206\u5b50\u8207\u7d30\u80de\u751f\u7269\u7814\u7a76\u6240\u66a8\u751f\u547d\u79d1\u5b78\u7cfb\uff0c<wbr \/>\u5f9e\u4e8b\u9ce5\u985e\u7684\u6f14\u5316\u907a\u50b3\u5b78\u3001\u57fa\u56e0\u9ad4\u5b78\u53ca\u6f14\u5316\u767c\u80b2\u751f\u7269\u5b78\u7814\u7a76\u3002<wbr \/>\u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b\uff0c\u5f9e\u4e8b\u79d1\u666e\u6587\u7ae0\u5beb\u4f5c\u3002<\/strong><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0\u72d7\u5974\u5011\u90fd\u77e5\u9053\uff0c\u62c9\u5e03\u62c9\u591a\u72ac\u7121\u6642\u7121\u523b\u90fd\u5c0d\u98df<\/p>\n","protected":false},"author":20,"featured_media":24550,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,26],"tags":[129,1765,2544,593,2545],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/05\/dog-1210559_960_720.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24549"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24549"}],"version-history":[{"count":4,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24549\/revisions"}],"predecessor-version":[{"id":32587,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24549\/revisions\/32587"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/24550"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24549"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24549"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24549"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}