{"id":24458,"date":"2016-05-18T00:07:20","date_gmt":"2016-05-17T16:07:20","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=24458"},"modified":"2018-08-03T14:38:36","modified_gmt":"2018-08-03T06:38:36","slug":"%e3%80%90%e7%a7%91%e5%ad%b8%e7%9f%ad%e6%b6%88%e6%81%af%e3%80%91%e8%80%81%e8%80%8c%e4%b8%8d%e8%a1%b0%e7%9a%84%e7%a7%98%e5%af%86","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=24458","title":{"rendered":"\u3010\u79d1\u5b78\u77ed\u6d88\u606f\u3011\u8001\u800c\u4e0d\u8870\u7684\u79d8\u5bc6"},"content":{"rendered":"<p><span style=\"color: #333399;\"><strong>\u25a0\u79d1\u5b78\u5bb6\u5b9a\u5e8f\u4e26\u5206\u6790\u4e86\u767e\u4f4d\u5065\u5eb7\u7684\u8001\u4eba\u57fa\u56e0\u9ad4\uff0c\u8a66\u5716\u5c0b\u627e\u51fa\u4ed6\u5011\u8001\u800c\u4e0d\u8870\u7684\u907a\u50b3\u4e4b\u9053\u3002<\/strong><\/span><\/p>\n<figure id=\"attachment_24460\" aria-describedby=\"caption-attachment-24460\" style=\"width: 375px\" class=\"wp-caption alignleft\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-24460\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/04\/0425.jpg\" alt=\"Erikson, GA et al. Cell. DOI: 10.1016\/j.cell.2016.03.022\" width=\"375\" height=\"375\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/04\/0425.jpg 375w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/04\/0425-150x150.jpg 150w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/04\/0425-300x300.jpg 300w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/><figcaption id=\"caption-attachment-24460\" class=\"wp-caption-text\">Erikson, GA et al. Cell. DOI: 10.1016\/j.cell.2016.03.022<\/figcaption><\/figure>\n<p><strong>\u64b0\u6587\uff5c<\/strong>\u9ec3\u8c9e\u7965<\/p>\n<p>\u7f8e\u570b\u65af\u514b\u91cc\u666e\u65af\u8f49\u8b6f\u79d1\u5b78\u7814\u7a76\u6240\u7684\u5fc3\u81df\u75c5\u5b78\u5bb6Eric Topol\u8868\u793a\uff0c\u9019\u500b\u7814\u7a76\u6700\u56f0\u96e3\u4e4b\u8655\uff0c\u5c31\u662f\u627e\u5230\u5e74\u904e\u516b\u5341\uff0c\u53ef\u662f\u537b\u672a\u53d7\u5230\u81ea\u9ad4\u514d\u75ab\u75be\u75c5\u3001\u8840\u6813\u3001\u764c\u75c7\u3001\u7cd6\u5c3f\u75c5\u3001\u5065\u5fd8\u3001\u5fc3\u81df\u75c5\u3001\u814e\u81df\u75c5\u3001\u4e2d\u98a8\u7b49\u56f0\u64fe\u7684\u8001\u4eba\u3002\u4ed6\u5011\u5f9e2007\u5e74\u8d77\u5c31\u5728\u7f8e\u570b\u548c\u5176\u4ed6\u570b\u5bb6\u7684\u5b89\u990a\u6a5f\u69cb\u5c0b\u627e\u672a\u66fe\u6210\u70ba\u85e5\u7f50\u7684\u6a02\u9f61\u4eba\u58eb\uff0c\u4ed6\u5011\u56e0\u70ba\u592a\u5065\u5eb7\u6240\u4ee5\u4e0d\u6703\u51fa\u73fe\u5728\u91ab\u9662\u88e1\u3002<\/p>\n<p>\u4ed6\u5011\u60f3\u8981\u77e5\u9053\u9019\u4e9b\u8001\u800c\u4e0d\u8870\u7684\u6a02\u9f61\u4eba\u58eb\uff0c\u7a76\u7adf\u662f\u5148\u5929\u57fa\u56e0\u512a\u826f\uff0c\u9084\u662f\u5f8c\u5929\u91ab\u7642\u7684\u4ecb\u5165\uff0c\u5982\u85e5\u7269\u63a7\u5236\u8840\u58d3\u548c\u81bd\u56fa\u9187\u3002\u4ed6\u5011\u627e\u5230\u4e861,400\u4f4d\u8001\u800c\u4e0d\u8870\u7684\u6a02\u9f61\u4eba\u58eb\uff0c\u4e26\u628a\u7f8e\u570b\u82f1\u82e5\u83ef\u8f49\u8b6f\u91ab\u5b78\u7814\u7a76\u6240\u6536\u96c6\u76841,507\u5e74\u6210\u4eba\u907a\u50b3\u8cc7\u6599\u7576\u5c0d\u7167\u7d44\u3002\u6392\u9664\u4e86\u7a2e\u65cf\u548c\u8840\u7de3\u7b49\u56e0\u7d20\uff0c\u4ed6\u5011\u7e3d\u5171\u5b9a\u5e8f\u4e26\u5206\u6790\u4e86511\u4f4d\u6a02\u9f61\u4eba\u58eb\u57fa\u56e0\u9ad4\uff0c\u4e26\u5c07686\u4f4d\u5c0d\u7167\u7d44\u6210\u4eba\u7576\u4f5c\u4e00\u822c\u65cf\u7fa4\u4f5c\u6bd4\u8f03\u3002<!--more--><\/p>\n<p>\u4ed6\u5011\u767c\u73fe\uff0c\u9019\u4e9b\u8001\u800c\u4e0d\u8870\u7684\u6a02\u9f61\u4eba\u58eb\u6bd4\u8d77\u63a7\u5236\u7d44\u78ba\u5b9a\u6709\u66f4\u4f4e\u7684\u963f\u8332\u6d77\u9ed8\u75c7\u53ca\u5fc3\u8840\u7ba1\u75be\u75c5\u907a\u50b3\u98a8\u96aa\uff0c\u56e0\u6b64\u4ed6\u5011\u53ef\u80fd\u5148\u5929\u4e0a\u5c31\u6bd4\u8f03\u6709\u512a\u52e2\u3002\u4e0d\u904e\u4ed6\u5011\u537b\u627e\u4e0d\u5230\u8b49\u64da\u6307\u51fa\u5728\u764c\u75c7\u3001\u7b2c\u4e8c\u578b\u7cd6\u5c3f\u75c5\u3001\u4e2d\u98a8\u7b49\u75be\u75c5\u907a\u50b3\u98a8\u96aa\u4e0a\u6709\u5dee\u5225\u3002\u9019\u500b\u7814\u7a76\u767c\u8868\u5728\u671f\u520a\u300a\u7d30\u80de\u300b\uff08<em>Cell<\/em>\uff09<\/p>\n<p>\u9019\u500b\u767c\u73fe\u9084\u672a\u80fd\u5920\u6210\u70ba\u5b9a\u8ad6\uff0c\u56e0\u70ba\u7121\u53ef\u5426\u8a8d\u7684\uff0c\u9019\u7fa4\u8001\u800c\u4e0d\u8870\u7684\u6a02\u9f61\u4eba\u58eb\u6bd4\u8d77\u63a7\u5236\u7d44\uff0c\u5e73\u5747\u6559\u80b2\u7a0b\u5ea6\u4e5f\u8f03\u9ad8\uff0c\u5df2\u77e5\u6559\u80b2\u7a0b\u5ea6\u548c\u58fd\u547d\u9577\u77ed\u76f8\u95dc\uff0c\u6240\u4ee5\u7121\u6cd5\u6392\u9664\u662f\u56e0\u70ba\u6559\u80b2\u7a0b\u5ea6\u8f03\u9ad8\u800c\u66f4\u6ce8\u91cd\u990a\u751f\u3002<\/p>\n<p><strong>\u539f\u5b78\u8853\u8ad6\u6587\uff1a<\/strong>Galina A. Erikson, STSI; Dale Bodian, Ph.D., ITMI; Manuel Rueda, Ph.D., STSI; Bhuvan Molparia, TSRI; Erick Scott, M.D., STSI; Ashley Scott-Van Zeeland, Ph.D., STSI; Sarah Topol, R.N., STSI; Nathan Wineinger, Ph.D., STSI; John Niederhuber, M.D., ITMI; Dr. Topol; and Torkamani. Whole-Genome Sequencing of a Healthy Aging Cohort. Cell, April 2016 DOI: 10.1016\/j.cell.2016.03.022<\/p>\n<p><strong>\u53c3\u8003\u8cc7\u6599\uff1a<\/strong><br \/>\n1. Scripps Health. \"<a href=\"https:\/\/www.sciencedaily.com\/releases\/2016\/04\/160421133647.htm\" target=\"_blank\">Link between cognitive decline genes, healthy aging suggested by study<\/a>.\" ScienceDaily. 21 April 2016.<br \/>\n2. Erika Check Hayden. <a href=\"http:\/\/www.nature.com\/news\/genetic-secrets-of-the-healthy-elderly-unveiled-1.19794\" target=\"_blank\">Genetic secrets of the healthy elderly unveiled. <\/a>Nature doi:10.1038\/nature.2016.19794<\/p>\n<p><span style=\"color: #333399;\"><strong>--<\/strong><\/span><br style=\"color: #000000;\" \/><span style=\"color: #333399;\"><strong>\u4f5c\u8005\uff1a<strong>\u9ec3\u8c9e\u7965 \u73fe\u4efb\u6559\u65bc\u570b\u7acb\u6e05\u83ef\u5927\u5b78\u5206\u5b50\u8207\u7d30\u80de\u751f\u7269\u7814\u7a76\u6240\u66a8\u751f\u547d\u79d1\u5b78\u7cfb\uff0c<wbr \/>\u5f9e\u4e8b\u9ce5\u985e\u7684\u6f14\u5316\u907a\u50b3\u5b78\u3001\u57fa\u56e0\u9ad4\u5b78\u53ca\u6f14\u5316\u767c\u80b2\u751f\u7269\u5b78\u7814\u7a76\u3002<wbr \/>\u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b\uff0c\u5f9e\u4e8b\u79d1\u666e\u6587\u7ae0\u5beb\u4f5c\u3002<\/strong><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0\u79d1\u5b78\u5bb6\u5b9a\u5e8f\u4e26\u5206\u6790\u4e86\u767e\u4f4d\u5065\u5eb7\u7684\u8001\u4eba\u57fa\u56e0\u9ad4<\/p>\n","protected":false},"author":20,"featured_media":24460,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,1025],"tags":[2526,129,2044,70,2527,1590],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/04\/0425.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24458"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24458"}],"version-history":[{"count":3,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24458\/revisions"}],"predecessor-version":[{"id":32548,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/24458\/revisions\/32548"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/24460"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24458"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24458"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24458"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}