{"id":24027,"date":"2016-04-13T00:06:55","date_gmt":"2016-04-12T16:06:55","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=24027"},"modified":"2018-08-03T14:33:36","modified_gmt":"2018-08-03T06:33:36","slug":"%e3%80%90%e8%b1%86%e9%a1%9e%e5%b9%b4%e5%b0%88%e9%a1%8c%e3%80%91%e8%a7%a3%e8%ae%80%e8%8f%9c%e8%b1%86%e7%9a%84%e5%9f%ba%e5%9b%a0%e9%ab%94%e5%af%86%e7%a2%bc","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=24027","title":{"rendered":"\u3010\u8c46\u985e\u5e74\u5c08\u984c\u3011\u89e3\u8b80\u83dc\u8c46\u7684\u57fa\u56e0\u9ad4\u5bc6\u78bc"},"content":{"rendered":"
\"\u5404\u7a2e\u4e0d\u540c\u7684\u83dc\u8c46\u3002\u5716\u7247\u4f86\u6e90\uff1awiki\"
\u5404\u7a2e\u4e0d\u540c\u7684\u83dc\u8c46\u3002\u5716\u7247\u4f86\u6e90\uff1awiki<\/figcaption><\/figure>\n

\u64b0\u6587\uff5c<\/strong>\u8449\u7da0\u8212<\/p>\n

\u83dc\u8c46\uff08Phaseolus vulgaris<\/em>\u00a0L.\uff09\uff0c\u5728\u53f0\u7063\u4e5f\u7a31\u70ba\u654f\u8c46\uff0c\u5728\u570b\u5916\u7a31\u70bacommon bean\u3001snap bean\uff0c\u662f\u8a31\u591a\u958b\u767c\u4e2d\u570b\u5bb6\u7684\u4eba\u6c11\u91cd\u8981\u7684\u86cb\u767d\u8cea\u4f86\u6e90\u3002\u5728\u9019\u4e9b\u570b\u5bb6\u88e1\uff0c\u4eba\u6c11\u7684\u4e3b\u98df\u662f\u5bcc\u542b\u6fb1\u7c89\u7684\u7c73\u3001\u7389\u7c73\u6216\u6a39\u85af\uff0c\u9019\u4e9b\u4e3b\u98df\u7684\u86cb\u767d\u8cea\u542b\u91cf\u4e0d\u9ad8\uff08\u7c73\u5927\u7d04\u662f2%\u3001\u6a39\u85af\u662f1.36%\u3001\u7389\u7c73\u5247\u4f9d\u54c1\u7a2e\u53ef\u4ee5\u5f9e5.2%-13.7%\u4e0d\u7b49\uff09\uff0c\u56e0\u6b64\u5728\u98f2\u98df\u4e2d\u52a0\u5165\u83dc\u8c46\u4ee5\u88dc\u5145\u86cb\u767d\u8cea\u662f\u76f8\u7576\u7406\u60f3\u7684\u3002\u76ee\u524d\u4f30\u8a08\u5168\u7403\u6709\u4e94\u5104\u4eba\u4f9d\u9760\u83dc\u8c46\u70ba\u91cd\u8981\u86cb\u767d\u8cea\u7684\u4f86\u6e90\u4e4b\u4e00\u3002\u83dc\u8c46\u53ef\u4ee5\u7b49\u6210\u719f\u5f8c\u6536\u7a6b\uff0c\u4e5f\u53ef\u4ee5\u5728\u8c46\u83a2\u5c1a\u7da0\u7684\u6642\u5019\u6536\u7a6b\u4f5c\u70ba\u9bae\u98df\u98df\u7528\uff0c\u7a31\u70bagreen bean\u3002\u57282010\u5e74\u4e7e\u8c46\u7522\u91cf\u6700\u5927\u7684\u570b\u5bb6\u662f\u5370\u5ea6\uff0c\u9752\u8c46\uff08\u672a\u6210\u719f\u7684\u8c46\u83a2\uff09\u7522\u91cf\u6700\u5927\u7684\u5247\u662f\u4e2d\u570b\u3002\u5728\u53f0\u7063\uff0c\u83dc\u8c46\u4e5f\u662f\u5f88\u53d7\u6b61\u8fce\u7684\u76e4\u4e2d\u98e7\uff0c\u7092\u4e00\u76e4\u9752\u7da0\u7684\u83dc\u8c46\uff0c\u633e\u4e00\u7b77\u5b50\u653e\u5728\u5634\u88e1\uff0c\u90a3\u6e05\u751c\u7684\u6ecb\u5473\uff0c\u771f\u662f\u9f52\u9830\u7559\u9999\uff01<\/p>\n

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\u96d6\u7136\u83dc\u8c46G19833\u54c1\u7cfb\u5df2\u7d93\u5b9a\u5e8f\u5b8c\u6210\uff0c\u4f46\u662f\u83dc\u8c46\u54c1\u7cfb\u7e41\u591a\u3001\u7279\u6027\u4e5f\u6709\u4e0d\u540c\uff0c\u56e0\u6b64\u897f\u73ed\u7259\u8207\u58a8\u897f\u54e5\u7684\u7814\u7a76\u5718\u968a\u9032\u884c\u4e86\u53e6\u4e00\u54c1\u7cfbBAT93\u7684\u5b9a\u5e8f\uff0c\u4e26\u9032\u884c\u5b83\u7684\u8f49\u9304\u9ad4\uff08transcriptome\uff09\u7684\u7814\u7a76\u3002\u9019\u4efd\u7814\u7a76\u5f4c\u8db3\u73cd\u8cb4\u7684\u662f\uff0c\u7814\u7a76\u5718\u968a\u4e0d\u50c5\u50c5\u53ea\u662f\u55ae\u7d14\u7684\u9032\u884c\u8f49\u9304\u9ad4\u7684\u7814\u7a76\uff0c\u9084\u6536\u96c6\u4e8610\u500b\u4e0d\u540c\u767c\u80b2\u968e\u6bb5\u7684\u83dc\u8c46\u8f49\u9304\u9ad4\u3001\u4ee5\u53ca\u4e03\u7a2e\u5668\u5b98\u3002\u5176\u4e2d10\u500b\u4e0d\u540c\u767c\u80b2\u968e\u6bb5\u5305\u62ec\u5f9e\u525b\u767c\u82bd\uff0848\u5c0f\u6642\uff09\u523086\u5929\u5927\uff08\u5df2\u7d93\u958b\u59cb\u7d50\u679c\u8207\u8870\u8001\uff09\uff0c\u800c\u4e03\u7a2e\u5668\u5b98\u5247\u6db5\u84cb\u4e86\u6839\u3001\u8396\u3001\u8449\u3001\u7a2e\u5b50\u3001\u8c46\u83a2\u3001\u82b1\u4ee5\u53ca\u9802\u82bd\uff1b\u771f\u662f\u4e00\u4efd\u975e\u5e38\u5b8c\u6574\u7684\u5206\u6790\uff01<\/p>\n

\u83dc\u8c46\u7684\u57fa\u56e0\u9ad4\u5171\u6709549.6 Mb\uff0c\u5305\u542b\u4e8630,491\u500b\u57fa\u56e0\uff1b\u9664\u6b64\u4e4b\u5916\uff0c\u9084\u67092,529\u500b\u5c0fRNA\u4ee5\u53ca1,033\u500b\u4e0d\u7522\u751f\u86cb\u767d\u8cea\u7684\u9577\u57fa\u56e0\uff08long non-coding genes\uff0clncRNA\uff09\u3002\u8207\u4eba\u76f8\u6bd4<\/a>\uff0c\u5927\u7d04\u662f\u4eba\u7684\u516d\u5206\u4e4b\u4e00\uff0c\u4f46\u82e5\u662f\u6bd4\u5c0d\u57fa\u56e0\u6578\u91cf\uff0c\u5247\u4eba\u7684\u57fa\u56e0\u6578\u76ee\u5927\u7d04\u53ea\u6709\u83dc\u8c46\u7684\u4e09\u5206\u4e4b\u4e8c\u3002<\/p>\n

\u6574\u9ad4\u4f86\u770b\uff0c\u83dc\u8c46\u7684\u57fa\u56e0\u9ad4\u5167\u670935%\u662f\u91cd\u8907\u7684\u5e8f\u5217\uff0c\u4e14\u5927\u90e8\u5206\u90fd\u662fLTR\uff08long terminal repeats\uff09\u3002\u7814\u7a76\u5718\u968a\u5728\u6bd4\u8f03\u6240\u6709\u6a23\u672c\u5f8c\uff0c\u9078\u51fa\u5728\u4e0d\u540c\u6a23\u672c\u9593\u8b8a\u7570\u4fc2\u6578\u6700\u4f4e\u7684\u524d\u767e\u5206\u4e4b\u5341\u4f5c\u70ba\u300c\u7ba1\u5bb6\u57fa\u56e0\u300d\uff08housekeeping gene\uff09\uff0c\u767c\u73fe\u5728BAT93\u76842,811\u500b\u7ba1\u5bb6\u57fa\u56e0\u4e2d\uff0c\u8207\u53e6\u4e00\u54c1\u7cfb\u9593\u53ea\u67091279\u500b\u76f8\u540c\uff0c\u800c\u8207\u5927\u8c46\u5247\u53ea\u6709195\u500b\u662f\u4e00\u6a23\u7684\u3002<\/p>\n

\u7814\u7a76\u5718\u968a\u4e5f\u767c\u73fe\uff0c\u82e5\u5c07\u6703\u5171\u540c\u8868\u73fe\u7684\u57fa\u56e0\u505a\u6210\u4e00\u500b\u9023\u7d50\u7db2\uff0c\u53ef\u4ee5\u767c\u73fe\u9023\u7d50\u6700\u9ad8\u7684125\u500b\u57fa\u56e0\u4e4b\u9593\u4e5f\u4e92\u76f8\u90fd\u6709\u9023\u7d50\u3002\u9ad8\u5ea6\u9023\u7d50\u7684\u57fa\u56e0\u591a\u534a\u90fd\u662f\u5728\u6f14\u5316\u4e0a\u6bd4\u8f03\u53e4\u8001\u3001\u6216\u662f\u6c92\u6709\u65c1\u7cfb\u540c\u6e90\u57fa\u56e0\uff08paralog\uff09\u7684\u57fa\u56e0\u5011\u3002\u5728\u6f14\u5316\u4e0a\u8f03\u53e4\u8001\u7684\u57fa\u56e0\u5011\uff0c\u8868\u73fe\u7684\u5340\u57df\u4e5f\u8f03\u70ba\u5ee3\u6cdb\uff1b\u800c\u65b0\u51fa\u73fe\u7684\u57fa\u56e0\u5247\u8868\u73fe\u5340\u57df\u8f03\u70ba\u4fb7\u9650\u3002<\/p>\n

\u4ee5\u9023\u7d50\u4f86\u5206\u6790\u3001\u6b78\u985e\uff0c\u5247\u53ef\u4ee5\u5f97\u523011\u500b\u9023\u7d50\u6a21\u7d44\u3002\u5176\u4e2d\u6700\u5927\u7684\u662f\u8207\u5149\u5408\u4f5c\u7528\u6709\u95dc\uff08\u8003\u616e\u5230\u690d\u7269\u662f\u5149\u5408\u81ea\u71df\u751f\u7269\uff0c\u9019\u5176\u5be6\u6c92\u4ec0\u9ebc\u597d\u9a5a\u8a1d\u7684\uff09\uff0c\u7b2c\u4e8c\u5927\u7684\u6a21\u7d44\u5247\u8207\u86cb\u767d\u8cea\u5b9a\u4f4d\uff08protein localization\uff09\u4ee5\u53ca\u7d30\u80de\u751f\u9577\u6709\u95dc\uff1b\u7b2c\u4e09\u5927\u5247\u662f\u8207\u6c27\u5316\u9084\u539f\u3001\u985e\u9ec3\u916e\u5408\u6210\u4ee5\u53ca\u6839\u7684\u767c\u80b2\u76f8\u95dc\u3002\u7531\u65bc\u985e\u9ec3\u916e\u5408\u6210\u8207\u8c46\u79d1\u690d\u7269\u8207\u6839\u7624\u83cc\u5efa\u7acb\u5171\u751f\u95dc\u4fc2\u6709\u95dc\uff0c\u56e0\u6b64\u4e5f\u76f8\u7576\u5408\u7406\u3002<\/p>\n

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\u5728\u6240\u6709\u6703\u7522\u751f\u86cb\u767d\u8cea\u7684\u57fa\u56e0\u88e1\uff0c\u670932%\u53ea\u8868\u73fe\u5728\u6839\u90e8\uff1b\u800c\u6709\u8a31\u591alncRNA\u53ea\u8868\u73fe\u5728\u679c\u5be6\u3002\u7a76\u7adf\u9019\u4e9blncRNA\u5728\u83dc\u8c46\u88e1\u662f\u5426\u6709\u4ec0\u9ebc\u7279\u6b8a\u7684\u89d2\u8272\uff0c\u9084\u76f8\u7576\u503c\u5f97\u7814\u7a76\u3002\u800c\u8207\u6839\u7624\u83cc\u5171\u751f\u76f8\u95dc\u7684\u57fa\u56e0\uff0c\u5247\u4e0d\u8ad6\u662f\u5728\u83dc\u8c46\u6216\u662f\u5728\u5176\u4ed6\u8c46\u79d1\u690d\u7269\u4e2d\u7684\u8868\u73fe\u91cf\u90fd\u8f03\u9ad8\u3002\u7531\u65bc\u8c46\u79d1\u690d\u7269\u5f88\u5bb9\u6613\u88ab\u7dda\u87f2\u611f\u67d3\uff0c\u7814\u7a76\u5718\u968a\u4e5f\u767c\u73fe\u83dc\u8c46\u88e1\u9762\uff0c\u9632\u79a6\u7dda\u87f2\u7684\u57fa\u56e0\u8868\u73fe\u91cf\u6709\u8f03\u9ad8\u3002<\/p>\n

\u5728\u8a31\u591a\u83dc\u8c46\u4e2d\uff0c\u7814\u7a76\u5718\u968a\u9078\u64c7\u4e86BAT93\u662f\u56e0\u70ba\u5b83\u7684\u6297\u75c5\u80fd\u529b\u8f03\u4f73\u3002\u4e0d\u904e\uff0c\u5206\u6790\u4e86\u57fa\u56e0\u9ad4\u5f8c\u767c\u73fe\uff0cBAT93\u4e26\u6c92\u6709\u7279\u5225\u7684\u6297\u75c5\u57fa\u56e0\uff1b\u56e0\u6b64\u7814\u7a76\u5718\u968a\u8a8d\u70ba\uff0cBAT93\u7684\u6297\u75c5\u529b\u4f73\u53ef\u80fd\u662f\u56e0\u70ba\u6297\u75c5\u57fa\u56e0\u7684\u5e8f\u5217\u8b8a\u7570\uff08\u4e0d\u540c\u7684\u5c0d\u5076\u57fa\u56e0\uff09\u3002<\/p>\n

\u83dc\u8c46\u53ef\u8aaa\u662f\u4e16\u754c\u4e0a\u4f5c\u70ba\u98df\u7269\u7684\u91cd\u8981\u8c46\u985e\u4e4b\u4e00\u3002\u4e0d\u8ad6\u662f\u6210\u719f\u5f8c\u63a1\u53d6\u4e7e\u8c46\u88fd\u4f5c\u98df\u7269\u3001\u6216\u662f\u5728\u672a\u6210\u719f\u6642\u63a1\u4e0b\u8c46\u83a2\u9bae\u98df\uff0c\u90fd\u76f8\u7576\u7406\u60f3\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u83dc\u8c46\u7684\u8449\u5b50\u4e5f\u53ef\u4ee5\u98df\u7528\u6216\u4f5c\u70ba\u7272\u755c\u7684\u98fc\u6599\u3002\u89e3\u8b80\u83dc\u8c46\u7684\u57fa\u56e0\u5bc6\u78bc\u53ea\u662f\u958b\u7aef\uff0c\u672a\u4f86\u5c1a\u9808\u8207\u53e6\u4e00\u54c1\u7cfb\u7684\u83dc\u8c46\u9032\u884c\u66f4\u591a\u7684\u6bd4\u5c0d\uff0c\u540c\u6642\u4e5f\u53ef\u4ee5\u8207\u5927\u8c46\u7b49\u8c46\u79d1\u690d\u7269\u7684\u57fa\u56e0\u9ad4\u9032\u884c\u66f4\u6df1\u5165\u7684\u5206\u6790\u3002\u7531\u65bcBAT93\u7684\u6297\u75c5\u529b\u4f73\uff0c\u672a\u4f86\u66f4\u9700\u8981\u9032\u4e00\u6b65\u8207\u5176\u4ed6\u54c1\u7cfb\u7684\u83dc\u8c46\u7684\u6297\u75c5\u57fa\u56e0\u9032\u884c\u66f4\u6df1\u5165\u7684\u7814\u7a76\uff0c\u627e\u51faBAT93\u6297\u75c5\u7684\u95dc\u9375\uff0c\u5c0d\u65bc\u4f5c\u7269\u6539\u826f\u61c9\u8a72\u6709\u76f8\u7576\u5927\u7684\u5e6b\u52a9\u3002<\/p>\n

\u53c3\u8003\u6587\u737b\uff1a<\/strong>
\nAnna Vlasova et. al., 2016.\u00a0Genome and transcriptome analysis of the Mesoamerican common bean and the role of gene duplications in establishing tissue and temporal specialization of genes<\/a>. Genome Biology. 17:32 DOI: 10.1186\/s13059-016-0883-6<\/p>\n

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