{"id":23683,"date":"2016-01-30T00:00:59","date_gmt":"2016-01-29T16:00:59","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=23683"},"modified":"2023-06-06T15:05:50","modified_gmt":"2023-06-06T07:05:50","slug":"%e3%80%90%e7%a7%91%e5%ad%b8%e5%8f%b2%e6%b2%99%e9%be%8d%e3%80%91%e7%98%a7%e7%96%be%e7%9a%84%e6%95%85%e4%ba%8b-2","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=23683","title":{"rendered":"\u3010\u79d1\u5b78\u53f2\u6c99\u9f8d\u3011\u7627\u75be\u7684\u6545\u4e8b"},"content":{"rendered":"<p style=\"text-align: center;\"><iframe src=\"https:\/\/www.youtube.com\/embed\/0AWaEhQJpcY\" width=\"640\" height=\"360\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p><strong>\u8b1b\u8005\uff5c<\/strong>\u4e2d\u592e\u7814\u7a76\u9662\u81e8\u6d77\u7814\u7a76\u7ad9\u7814\u7a76\u54e1 \u56b4\u5b8f\u6d0b<br \/>\n<strong>\u64b0\u6587\uff5c<\/strong>\u738b\u5e0c\u6587<\/p>\n<p>\u73fe\u5728\u7684\u4eba\u5df2\u77e5\u7627\u75be\u662f\u4e00\u7a2e\u868a\u5a92\u75c5\uff0c\u662f\u7d93\u7531\u7279\u5b9a\u7684\u868a\u5b50\u53ee\u54ac\u52d5\u7269\uff0c\u6563\u64ad\u7627\u539f\u87f2\u7684\u6025\u6027\u50b3\u67d3\u75c5\u3002\u4f46\u5728\u904e\u53bb\u5b83\u7684\u50b3\u67d3\u9014\u5f91\u548c\u6cbb\u7642\u65b9\u5f0f\u90fd\u5c1a\u672a\u88ab\u767c\u73fe\uff0c\u56e0\u7627\u75be\u800c\u6b7b\u4ea1\u7684\u4eba\u591a\u4e0d\u52dd\u6578\uff0c\u751a\u81f3\u76f4\u52302013\u5e74\uff0c\u611f\u67d3\u7627\u75be\u7684\u4eba\u4ecd\u9ad8\u90541.98\u5104\uff0c\u800c\u5f97\u75c5\u6b7b\u4ea1\u8005\u66f4\u670958.4\u842c\u4e4b\u591a\u3002<\/p>\n<p>\u7627\u75be\u75c5\u4f8b\u5927\u591a\u51fa\u73fe\u5728\u8d64\u9053\u9644\u8fd1\u7684\u71b1\u5e36\u548c\u4e9e\u71b1\u5e36\u5730\u5340\uff0c\u5305\u62ec\u4e9e\u6d32\u3001\u62c9\u4e01\u7f8e\u6d32\u548c\u6492\u54c8\u62c9\u4ee5\u5357\u7684\u975e\u6d32\u3002\u5176\u4e2d\u60e1\u6027\u7627\u539f\u87f2\uff08<em>Plasmodium falciparum<\/em>\uff09\u5f15\u767c\u7684\u7627\u75be\u662f\u6700\u5371\u96aa\u7684\u4e00\u7a2e\uff0c\u5176\u4f75\u767c\u75c7\u548c\u6b7b\u4ea1\u7387\u90fd\u662f\u6700\u9ad8\u7684\u3002<!--more--><\/p>\n<p>\u8a72\u7a2e\u7627\u539f\u87f2\u64da\u4fe1\u5df2\u5b58\u57285\u842c\u81f310\u842c\u5e74\uff0c\u4e0d\u904e\u5176\u65cf\u7fa4\u5927\u5c0f\u662f\u5230\u5927\u7d041\u842c\u5e74\u524d\u624d\u958b\u59cb\u64f4\u5927\uff0c\u548c\u8fb2\u696d\u7684\u9032\u6b65\u53ca\u4eba\u985e\u805a\u843d\u7684\u8a95\u751f\u5927\u6709\u95dc\u4fc2\u3002<\/p>\n<p>\u95dc\u65bc\u7627\u75be\u7684\u7d00\u9304\uff0c\u5728\u897f\u5143\u524d2700\u5e74\u7684\u4e2d\u570b\u5c31\u5df2\u5b58\u5728\uff0c\u5176\u4e2d\u63d0\u5230\u4e86\u5176\u7279\u6709\u7684\u9031\u671f\u6027\u767c\u71d2\u3002\u96c5\u5178\u7684\u5e0c\u6ce2\u514b\u62c9\u5e95\uff08460\uff0d370BC\uff09\u4ea6\u5c0d\u6b64\u6709\u904e\u7d00\u9304\uff0c\u7f85\u99ac\u7684\u79d1\u9b6f\u9081\u62c9\u5247\u8a8d\u70ba\u6b64\u7a2e\u75be\u75c5\u548c\u6cbc\u6fa4\u4e2d\u7684\u6606\u87f2\u6709\u95dc\u3002\u5f9e\u53e4\u5230\u4eca\u7684\u8a31\u591a\u6230\u5f79\uff0c\u53d7\u5230\u7627\u75be\u5f71\u97ff\u7684\u4e5f\u4e0d\u53ef\u52dd\u6578\u3002\u56b4\u8001\u5e2b\u4ee51741\u5e74\u897f\u73ed\u7259\u6d77\u8ecd\u653b\u6253\u54e5\u502b\u6bd4\u4e9e\u3001\u4ee5\u53ca\u767c\u751f\u5728\u53f0\u7063\u7684\u7261\u4e39\u793e\u4e8b\u4ef6\u70ba\u4f8b\uff0c\u8b93\u807d\u773e\u4e86\u89e3\u5230\uff0c\u767c\u751f\u5728\u6230\u5834\u4e0a\u7684\u7627\u75be\u521d\u9ad4\u9a57\uff0c\u662f\u6703\u4ee5\u6557\u6230\u4f5c\u70ba\u7d42\u7d50\u7684\u3002<\/p>\n<p>\u7627\u75be\u7684\u75c5\u539f\u7684\u767c\u73fe\u8981\u5230\u897f\u51431880\u5e74\uff0c\u624d\u7531\u6cd5\u570b\u8ecd\u91ab\u590f\u723e\u00b7\u8def\u6613\u00b7\u963f\u65b9\u65af\u00b7\u62c9\u97cb\u6717\uff08Charles Louis Alphonse Laveran\uff09\u89c0\u5bdf\u5230\u5728\u75c5\u60a3\u7684\u7d05\u8840\u7403\u4e2d\u5b58\u5728\u7684\u5bc4\u751f\u87f2\u3002\u4ed6\u56e0\u6b64\u63d0\u51fa\u7627\u75be\u662f\u7531\u9019\u7a2e\u5bc4\u751f\u87f2\u6240\u5f15\u8d77\uff0c\u9019\u540c\u6642\u662f\u53f2\u4e0a\u7b2c\u4e00\u6b21\u539f\u751f\u52d5\u7269\u88ab\u6307\u51fa\u70ba\u75c5\u539f\u3002\u7531\u65bc\u9019\u4e00\u767c\u73fe\u548c\u4e4b\u5f8c\u7684\u7814\u7a76\uff0c\u4ed6\u57281907\u5e74\u7372\u5f97\u4e86\u8afe\u8c9d\u723e\u751f\u7406\u91ab\u5b78\u734e\u3002<\/p>\n<p>\u800c\u5728\u4e00\u5e74\u5f8c\uff0c\u6b63\u5728\u6cbb\u7642\u611f\u67d3\u9ec3\u71b1\u75c5\u75c5\u60a3\u7684\u53e4\u5df4\u91ab\u5e2b\u5361\u6d1b\u65af\u00b7\u80e1\u5b89\u00b7\u82ac\u840a\uff08Carlos Juan Finlay\uff09\u7d66\u51fa\u4e86\u662f\u868a\u5b50\u5728\u4eba\u4e4b\u9593\u50b3\u64ad\u75be\u75c5\u7684\u6709\u529b\u8b49\u64da\u3002\u4ed6\u7684\u7814\u7a76\u662f\u6839\u64da\u65e9\u5148\u7d04\u897f\u4e9eC.\u8afe\u7279\uff08Josiah C. Nott\uff09\u7684\u5047\u8aaa\u548c\u71b1\u5e36\u91ab\u5b78\u4e4b\u7236\uff0cSir Patrick Manson\uff08\u842c\u5df4\u5fb7\uff0c\u53c8\u8b6f\u767d\u6587\u4fe1\u6216\u5b5f\u751f\uff09\u7684\u7814\u7a76\u6240\u5f97\u51fa\u3002<\/p>\n<p>\u91dd\u5c0d\u7627\u75be\u6709\u6548\u7684\u6cbb\u7642\u65b9\u6cd5\u6700\u65e9\u767c\u73fe\u65bc\u91d1\u96de\u7d0d\u6a39\uff0c\u5b83\u7684\u6a39\u76ae\u542b\u6709\u594e\u5be7\u3002\u9019\u7a2e\u6a39\u591a\u5206\u4f48\u65bc\u5b89\u5730\u65af\u5c71\u8108\u548c\u79d8\u9b6f\uff0c\u79d8\u9b6f\u7684\u571f\u8457\u6703\u5c07\u7260\u505a\u6210\u85e5\u9152\u63a7\u5236\u767c\u71d2\uff0c\u5f8c\u7531\u8036\u7a4c\u6703\u58eb\u57281640\u5e74\u5e36\u56de\u6b50\u6d32\uff0c\u4e26\u57281677\u5e74\u4ee5\u6297\u7627\u75be\u85e5\u7269\u4e4b\u540d\u88ab\u52a0\u5165\u300c\u502b\u6566\u85e5\u5178\u300d\u3002\u4e0d\u904e\u594e\u5be7\u662f\u5230\u4e861820\u5e74\u624d\u6210\u529f\u5f9e\u6a39\u76ae\u4e2d\u88ab\u5206\u96e2\u51fa\u4f86\uff0c\u4e26\u7531\u6cd5\u570b\u5316\u5b78\u5bb6\u76ae\u57c3\u723e\u00b7\u7d04\u745f\u592b\u00b7\u4f69\u723e\u8482\u57c3\uff08Pierre Joseph Pelletier\uff09\u548cJoseph Bienaim\u00e9 Caventou\u547d\u540d\u3002<\/p>\n<p>\u76f4\u5230\u6709\u65b0\u7684\u85e5\u7269\u88ab\u7814\u7a76\u51fa\u4f86\u4e4b\u524d\uff0c\u594e\u5be7\u90fd\u662f\u4e3b\u8981\u7684\u6297\u7627\u75be\u85e5\u7269\u3002\u5230\u4e861940\u5e74\u4ee3\uff0c\u7531\u62dc\u8033\u85e5\u5ee0\u7684Hans Andersag\u767c\u660e\u7684\u6c2f\u55b9\u66ab\u6642\u53d6\u4ee3\u4e86\u594e\u5be7\u7684\u4f4d\u7f6e\uff0d\uff0d\u76f4\u5230\u6c2f\u55b9\u5728\u4e16\u754c\u5404\u5730\u90fd\u7522\u751f\u4e86\u6297\u85e5\u6027\u3002<\/p>\n<p>\u5728\u9752\u84bf\u7d20\uff08artemisinin\uff09\u88ab\u767c\u73fe\u4e4b\u524d\uff0c\u9752\u84bf\u5728\u4e2d\u570b\u5df2\u7d93\u88ab\u4e2d\u91ab\u4f7f\u7528\u4e86\u8fd12000\u5e74\u30021596\u5e74\uff0c\u674e\u6642\u73cd\u5728\u300a\u672c\u8349\u525b\u76ee\u300b\u4e2d\u63a8\u9078\u4e86\u9752\u84bf\u8336\u70ba\u6cbb\u7642\u7627\u75be\u7684\u85e5\u7269\u3002\u9752\u84bf\u7d20\u5247\u662f\u57281970\u7531\u5c60\u5466\u5466\u7b49\u79d1\u5b78\u5bb6\u70ba\u4e86\u5c0b\u627e\u65b0\u7684\u7627\u75be\u7279\u6548\u85e5\uff0c\u5617\u8a66\u4e86\u6578\u767e\u7a2e\u8349\u85e5\u5f8c\uff0c\u5f9e\u9752\u84bf\u4e2d\u63d0\u7149\u51fa\uff0c\u4e26\u6210\u70ba\u60e1\u6027\u7627\u75be\u7684\u63a8\u85a6\u85e5\u7269\u3002\u5c60\u5466\u5466\u8868\u793a\u5979\u662f\u53d7\u845b\u6d2a\u6240\u8457\u7684\u300a\u8098\u5f8c\u5099\u6025\u65b9\u300b\u5f71\u97ff\uff0c\u5f8c\u4f86\u5979\u4e5f\u56e0\u6b64\u57282015\u5e74\u7372\u5f97\u8afe\u8c9d\u723e\u751f\u7406\u91ab\u5b78\u734e\u3002<\/p>\n<p>\u9664\u4e86\u91dd\u5c0d\u75be\u75c5\u672c\u8eab\u7684\u85e5\u7269\uff0c\u79d1\u5b78\u5bb6\u4e5f\u8a66\u8457\u627e\u51fa\u80fd\u6bba\u6b7b\u7627\u868a\u7684\u65b9\u5f0f\u3002\u9996\u5148\u7528\u5728\u5ba4\u5167\u5674\u7051\u662fDDT\uff0c\u4f46\u96a8\u8457DDT\u5927\u91cf\u4f7f\u7528\u5f8c\uff0c\u5b83\u7684\u7684\u8ca0\u9762\u4f5c\u7528\u6108\u4f86\u6108\u5ee3\u70ba\u4eba\u77e5\uff0c\u6700\u7d42\u57281970\u5e74\u4ee3\u88ab\u8a31\u591a\u570b\u5bb6\u5168\u9762\u7981\u7528\u3002<\/p>\n<p>\u5982\u4eca\u5c0d\u7627\u75be\u5f97\u4e86\u89e3\u6108\u4f86\u6108\u591a\uff0c\u4e5f\u51fa\u73fe\u4e86\u5176\u4ed6\u91dd\u5c0d\u9019\u7a2e\u75be\u75c5\u7684\u7814\u7a76\uff0c\u5982\u975e\u91cd\u75c7\u7627\u75be\u53ef\u7528\u9752\u84bf\u7d20\u806f\u5408\u7642\u6cd5\uff08 artemisinin-combination therapy\uff0cACTs\uff09\u9032\u884c\u6cbb\u7642\u3002\u76ee\u524d\u6709\u8a31\u591a\u7814\u7a76\u5247\u91dd\u5c0d\u7627\u539f\u87f2\u751f\u547d\u9031\u671f\u5e72\u64fe\uff0c\u4f7f\u5b83\u7121\u6cd5\u9032\u5165\u7d05\u8840\u7403\u6216\u662f\u7121\u6cd5\u7e41\u6b96\u7b49\u7b49\uff0c\u4ee5\u6c42\u6839\u9664\u7627\u75be\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u8b1b\u8005\uff5c\u4e2d\u592e\u7814\u7a76\u9662\u81e8\u6d77\u7814\u7a76\u7ad9\u7814\u7a76\u54e1 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