

{"id":23618,"date":"2016-02-03T00:26:23","date_gmt":"2016-02-02T16:26:23","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=23618"},"modified":"2018-08-03T14:25:17","modified_gmt":"2018-08-03T06:25:17","slug":"%e3%80%90%e5%af%b5%e7%89%a9%e7%9f%ad%e6%b6%88%e6%81%af%e3%80%91%e9%bb%91%e7%99%bd%e8%8a%b1%e6%96%91%e8%b2%93%e7%9a%84%e9%81%ba%e5%82%b3%e4%b9%8b%e8%ac%8e","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=23618","title":{"rendered":"\u3010\u5bf5\u7269\u77ed\u6d88\u606f\u3011\u9ed1\u767d\u82b1\u6591\u8c93\u7684\u907a\u50b3\u4e4b\u8b0e"},"content":{"rendered":"<figure id=\"attachment_23619\" aria-describedby=\"caption-attachment-23619\" style=\"width: 450px\" class=\"wp-caption alignleft\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-23619\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/01\/0125-1024x680.jpg\" alt=\"Photo credit: Hisashi from Japan, CC BY-SA 2.0\" width=\"450\" height=\"299\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/01\/0125-1024x680.jpg 1024w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/01\/0125-300x199.jpg 300w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/01\/0125-800x531.jpg 800w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/01\/0125-600x399.jpg 600w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/01\/0125.jpg 1269w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><figcaption id=\"caption-attachment-23619\" class=\"wp-caption-text\">Photo credit: Hisashi from Japan, CC BY-SA 2.0<\/figcaption><\/figure>\n<p><strong>\u64b0\u6587\uff5c<\/strong>\u9ec3\u8c9e\u7965<\/p>\n<p>\u70ba\u4f55\u9ed1\u767d\u8c93\u8eab\u4e0a\u6703\u6709\u5169\u7a2e\u6bdb\u8272\u5462\uff1f\u79d1\u5b78\u5bb6\u767c\u73fe\uff0c\u9019\u6a23\u7684\u82b1\u6591\u662f\u52d5\u7269\u5728\u5b50\u5bae\u5167\u767c\u80b2\u6642\uff0c\u8272\u7d20\u7d30\u80de\u7684\u5206\u88c2\u8b8a\u6162\u6240\u9020\u6210\u7684\u3002<\/p>\n<p>\u9ed1\u767d\u82b1\u6591\u5728\u4e00\u4e9b\u99ac\u8eab\u4e0a\u4e5f\u53ef\u770b\u898b\u3002\u6b63\u5e38\u4f86\u8aaa\uff0c\u8272\u7d20\u7d30\u80de\u8a72\u5f9e\u80cc\u90e8\u64f4\u6563\u5230\u5168\u8eab\u5305\u62ec\u809a\u5b50\u3002\u5728\u82b1\u6591\u7684\u54fa\u4e73\u52d5\u7269\u8eab\u4e0a\uff0c\u8272\u7d20\u7d30\u80de\u4e0d\u8db3\u4ee5\u8986\u84cb\u5168\u8eab\uff0c\u6240\u4ee5\u7559\u4e0b\u5927\u7247\u767d\u8272\u7684\u6bdb\u9aee\uff0c\u4e00\u822c\u4e0a\u809a\u5b50\u548c\u984d\u982d\u6703\u662f\u767d\u8272\u7684\u3002<\/p>\n<p>\u82f1\u570b\u725b\u6d25\u5927\u5b78\u3001\u5df4\u65af\u5927\u5b78\u3001\u611b\u4e01\u5821\u5927\u5b78\u7684\u79d1\u5b78\u5bb6\uff0c\u5229\u7528\u4e86\u6578\u5b78\u6a21\u578b\u7d50\u5408\u52d5\u7269\u5be6\u9a57\u4f86\u89e3\u91cb\u82b1\u6591\u7684\u5f62\u6210\u3002\u904e\u53bb\u8a8d\u70ba\u90a3\u4e9b\u9ed1\u767d\u7684\u82b1\u6591\u662f\u56e0\u70ba\u8272\u7d20\u7d30\u80de\u7684\u79fb\u52d5\u592a\u6162\u4e86\uff0c\u662f\u56e0\u70ba\u4e00\u7a2e\u7a31\u4f5c<em>KIT<\/em>\u7684\u57fa\u56e0\u7a81\u8b8a\u6240\u5c0e\u81f4\u7684\u3002<em>KIT<\/em>\u57fa\u56e0\u7de8\u78bc\u4e86\u53d7\u9ad4\u916a\u6c28\u9178\u6fc0\u9176\uff08Receptor Tyrosine Kinase\uff09\uff0c\u662f\u4e00\u7a2e\u819c\u86cb\u767d\u53d7\u9ad4\uff0c\u819c\u5916\u90e8\u5206\u529f\u80fd\u70ba\u53d7\u9ad4\uff0c\u819c\u5167\u90e8\u5206\u70ba\u916a\u6c28\u9178\u6fc0\u9176 \uff0c\u53ef\u5c07\u76ee\u6a19\u86cb\u767d\u7684\u916a\u80fa\u9178\uff08Tyr\uff09\u90e8\u5206\u78f7\u9178\u5316\uff0c\u85c9\u6b64\u50b3\u905e\u8a0a\u865f\uff0c\u5728\u7d30\u80de\u751f\u9577\u3001\u589e\u6b96\u3001\u5206\u5316\u4e2d\u5177\u6709\u91cd\u8981\u4f5c\u7528\u3002<!--more--><\/p>\n<p>\u53ef\u662f\u4ed6\u5011\u767c\u73fe\uff0c\u539f\u4f86<em>KIT<\/em>\u7684\u7a81\u8b8a\u6e1b\u7de9\u7684\u662f\u7d30\u80de\u5206\u88c2\u901f\u7387\uff0c\u800c\u975e\u79fb\u52d5\u901f\u7387\u3002\u56e0\u70ba\u7d30\u80de\u5206\u88c2\u8b8a\u6162\uff0c\u6700\u7d42\u6c92\u6709\u8db3\u5920\u7684\u8272\u7d20\u7d30\u80de\u8986\u84cb\u5168\u8eab\uff0c\u6240\u4ee5\u5f62\u6210\u9ed1\u767d\u82b1\u6591\u3002\u9019\u500b\u767c\u73fe\u767c\u8868\u5728\u300a\u81ea\u7136\u901a\u8a0a\u300b\uff08<em>Nature Communications<\/em>\uff09\u3002<\/p>\n<p>\u9664\u4e86<em>KIT<\/em>\u57fa\u56e0\uff0c\u4e5f\u6709\u5176\u4ed6\u57fa\u56e0\u5f71\u97ff\u82b1\u6591\u7684\u7d0b\u8def\uff0c\u90fd\u53ef\u5229\u7528\u6578\u5b78\u6a21\u578b\u4f86\u7814\u7a76\u3002\u96d6\u7136\u82b1\u6591\u4e0d\u6703\u9020\u6210\u75be\u75c5\uff0c\u53ef\u662f\u66f4\u56b4\u91cd\u7684\u7a81\u8b8a\u6703\u9020\u6210\u8178\u9053\u795e\u7d93\u75c5\u8b8a\uff08Neurocristopathy\uff09\u800c\u5c0e\u81f4\u807d\u529b\u3001\u8996\u89ba\u3001\u6d88\u5316\u9053\u548c\u5fc3\u8840\u7ba1\u7684\u75c5\u8b8a\uff0c\u662f\u795e\u7d93\u810a\u7d30\u80de\u5206\u88c2\u7684\u7570\u5e38\u9020\u6210\u7684\u3002\u6240\u4ee5\u4ed6\u5011\u7684\u7814\u7a76\u65b9\u6cd5\u4e5f\u53ef\u80fd\u80fd\u5920\u61c9\u7528\u5728\u5176\u4ed6\u76f8\u95dc\u75be\u75c5\u7684\u7814\u7a76\u4e0a\u3002<\/p>\n<p><strong>\u539f\u5b78\u8853\u8ad6\u6587\uff1a<\/strong><br \/>\nRichard L. Mort, Robert J. H. Ross, Kirsten J. Hainey, Olivia J. Harrison, Margaret A. Keighren, Gabriel Landini, Ruth E. Baker, Kevin J. Painter, Ian J. Jackson, Christian A. Yates. Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model.Nature Communications, 2016; 7: 10288 DOI: 10.1038\/NCOMMS10288<\/p>\n<p><strong>\u53c3\u8003\u8cc7\u6599\uff1a<\/strong><br \/>\n1. Christian Yates\/The Conversation. <a href=\"http:\/\/www.popsci.com\/why-some-cats-look-like-they-are-wearing-tuxedos\" target=\"_blank\" rel=\"noopener noreferrer\">WHY SOME CATS LOOK LIKE THEY ARE WEARING TUXEDOS.<\/a> Popular Science. January 7, 2016.<br \/>\n2. University of Bath. \"<a href=\"http:\/\/www.sciencedaily.com\/releases\/2016\/01\/160106091746.htm\" target=\"_blank\" rel=\"noopener noreferrer\">How two-tone cats get their patches comes to light in cell study.<\/a>\" ScienceDaily, 6 January 2016.<br \/>\n3. JACK HARDY , JASPER HAMILL. <a href=\"http:\/\/www.mirror.co.uk\/news\/technology-science\/science\/scientists-crack-mystery-how-cats-7126149\" target=\"_blank\" rel=\"noopener noreferrer\">Scientists crack the mystery of how cats get their cute coloured coats.<\/a> Mirror. 6 JAN 2016.<\/p>\n<p><span style=\"color: #333399;\"><strong>--<\/strong><\/span><br style=\"color: #000000;\" \/><span style=\"color: #333399;\"><strong>\u4f5c\u8005\uff1a<strong>\u9ec3\u8c9e\u7965 \u73fe\u4efb\u6559\u65bc\u570b\u7acb\u6e05\u83ef\u5927\u5b78\u5206\u5b50\u8207\u7d30\u80de\u751f\u7269\u7814\u7a76\u6240\u66a8\u751f\u547d\u79d1\u5b78\u7cfb\uff0c<wbr \/>\u5f9e\u4e8b\u9ce5\u985e\u7684\u6f14\u5316\u907a\u50b3\u5b78\u3001\u57fa\u56e0\u9ad4\u5b78\u53ca\u6f14\u5316\u767c\u80b2\u751f\u7269\u5b78\u7814\u7a76\u3002<wbr \/>\u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b\uff0c\u5f9e\u4e8b\u79d1\u666e\u6587\u7ae0\u5beb\u4f5c\u3002<\/strong><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u64b0\u6587\uff5c\u9ec3\u8c9e\u7965 \u70ba\u4f55\u9ed1\u767d\u8c93\u8eab\u4e0a\u6703\u6709\u5169\u7a2e\u6bdb\u8272<\/p>\n","protected":false},"author":20,"featured_media":23619,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,26],"tags":[129,1765,864,1920,1590,2347],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/01\/0125.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/23618"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23618"}],"version-history":[{"count":3,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/23618\/revisions"}],"predecessor-version":[{"id":32485,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/23618\/revisions\/32485"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/23619"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23618"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23618"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23618"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}