{"id":23490,"date":"2016-01-20T00:34:44","date_gmt":"2016-01-19T16:34:44","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=23490"},"modified":"2018-08-01T16:49:30","modified_gmt":"2018-08-01T08:49:30","slug":"%e3%80%90%e7%b9%bd%e7%b4%9b%e7%94%9f%e6%85%8b%e3%80%91%e9%a6%b4%e5%8c%96%e6%90%9e%e5%a3%9e%e4%ba%86%e7%8b%97%e7%8b%97%e5%9f%ba%e5%9b%a0","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=23490","title":{"rendered":"\u3010\u7e7d\u7d1b\u751f\u614b\u3011\u99b4\u5316\u641e\u58de\u4e86\u72d7\u72d7\u57fa\u56e0"},"content":{"rendered":"<p><span style=\"color: #333399;\"><strong>\u25a0\u72d7\u72d7\u7121\u7591\u662f\u4eba\u985e\u6700\u597d\u7684\u670b\u53cb\uff0c\u611b\u72d7\u7684\u4eba\u985e\u66f4\u662f\u57f9\u80b2\u9078\u62d4\u51fa\u4e94\u82b1\u516b\u9580\u7684\u7d14\u7a2e\u72d7\u3002\u53ef\u662f\u79d1\u5b78\u5bb6\u767c\u73fe\uff0c\u4eba\u985e\u7684\u80b2\u7a2e\u8b93\u72d7\u72d7\u5e36\u4e86\u66f4\u591a\u4e0d\u826f\u7684\u57fa\u56e0\u7a81\u8b8a\u3002<\/strong><\/span><\/p>\n<figure id=\"attachment_23493\" aria-describedby=\"caption-attachment-23493\" style=\"width: 450px\" class=\"wp-caption alignleft\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-23493\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/01\/2395724941_2b6908079a_b-640x425.jpg\" alt=\"flickr user: sabianmaggy\" width=\"450\" height=\"299\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/01\/2395724941_2b6908079a_b-640x425.jpg 640w, 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sabianmaggy<\/figcaption><\/figure>\n<p><strong>\u64b0\u6587\uff5c<\/strong>\u9ec3\u8c9e\u7965<\/p>\n<p>\u8209\u4f8b\u4f86\u8aaa\uff0c\u4eba\u985e\u57f9\u990a\u51fa\u7684\u9ed1\u72d7\uff0c\u8b93\u7260\u5011\u5e36\u6709\u8f03\u591a\u62f7\u8c9d\u6578\u7684<em>KITLG<\/em>\u57fa\u56e0\uff0c\u9019\u8b93\u7260\u5011\u7684\u722a\u5e8a\u5bb9\u6613\u767c\u751f\u9c57\u72c0\u7d30\u80de\u764c\uff0c\u90a3\u662f\u4e00\u985e\u4e0a\u76ae\u7d44\u7e54\u7d30\u80de\u3001\u9c57\u72c0\u7d30\u80de\u7522\u751f\u75c5\u8b8a\u7684\u764c\u75c7\u3002<\/p>\n<p>\u4eba\u985e\u5728\u99b4\u990a\u72d7\u72d7\u7684\u904e\u7a0b\u4e2d\uff0c\u53ef\u80fd\u6311\u4e86\u8f03\u8a0e\u559c\u7684\u7070\u72fc\uff0c\u4f8b\u5982\u6bd4\u8f03\u6eab\u99b4\u53c8\u6a5f\u667a\u80fd\u5e6b\u4eba\u72e9\u7375\u7684\u3002\u9019\u4eba\u64c7\u7684\u904e\u7a0b\u4e2d\u4e0d\u514d\u6709\u6216\u591a\u6216\u5c11\u7684\u8fd1\u89aa\u7e41\u6b96\uff0c\u96d6\u7136\u6311\u51fa\u4e86\u597d\u7684\u6027\u72c0\uff0c\u4f46\u5982\u679c\u7260\u5011\u7956\u5148\u6709\u4e0d\u826f\u7684\u57fa\u56e0\uff0c\u4e5f\u5bb9\u6613\u50b3\u905e\u7d66\u5f8c\u4ee3\u5b50\u5b6b\uff0c\u800c\u5f8c\u4ee3\u7684\u907a\u50b3\u591a\u6a23\u6027\u7684\u8b8a\u4f4e\uff0c\u4f7f\u4e0d\u826f\u57fa\u56e0\u66f4\u96e3\u88ab\u5254\u9664\u3002<!--more--><\/p>\n<p>\u4e26\u975e\u6240\u6709\u7a81\u8b8a\u90fd\u662f\u6709\u5bb3\u7684\uff0c\u6709\u76f8\u7576\u5927\u6bd4\u4f8b\u7684DNA\u7a81\u8b8a\u662f\u4e2d\u6027\u7684\uff0c\u53ef\u662f\u5018\u82e5DNA\u7684\u7a81\u8b8a\u6539\u8b8a\u4e86\u86cb\u767d\u8cea\u7684\u5e8f\u5217\u548c\u7d50\u69cb\uff0c\u90a3\u9ebc\u5c31\u6709\u53ef\u80fd\u5c0d\u86cb\u767d\u8cea\u529f\u80fd\u7522\u751f\u4e0d\u826f\u5f71\u97ff\u3002\u6709\u4e9b\u4e0d\u826f\u7a81\u8b8a\u6703\u88ab\u5929\u64c7\u6dd8\u6c70\uff0c\u53ef\u662f\u5728\u4eba\u5de5\u80b2\u7a2e\u7684\u60c5\u6cc1\u4e0b\uff0c\u4e0d\u826f\u7a81\u8b8a\u5018\u82e5\u63a5\u8fd1\u6709\u5229\u7684\u7a81\u8b8a\uff0c\u53cd\u800c\u6703\u88ab\u4eba\u985e\u7d66\u6311\u9078\u51fa\u4f86\u3002\u53c8\u6216\u8005\u6709\u4e9b\u7a81\u8b8a\u662f\u4eba\u985e\u559c\u611b\u7684\uff0c\u53ef\u662f\u537b\u6709\u4e0d\u826f\u526f\u4f5c\u7528\u3002<\/p>\n<p>\u70ba\u4e86\u77ad\u89e3\u99b4\u5316\u7684\u904e\u7a0b\u5c0d\u73fe\u4ee3\u5bb6\u72ac\u7684\u5f71\u97ff\uff0c\u7f8e\u570b\u52a0\u5dde\u5927\u5b78\u6d1b\u6749\u78ef\u5206\u6821\u7684\u65cf\u7fa4\u907a\u50b3\u5b78\u5bb6Kirk Lohmueller\u548cClare Marsden\u5206\u6790\u4e86\u5c6c\u65bc34\u7a2e\u7d14\u7a2e\u72d7\u768446\u96bb\u72d7\u7684\u57fa\u56e0\u9ad4\u3002\u4ed6\u5011\u628a\u9019\u4e9b\u7d14\u7a2e\u72d7\u7684\u57fa\u56e0\u9ad4\uff0c\u548c19\u96bb\u7070\u72fc\u300125\u96bb\u9109\u6751\u72d7\u53ca\u91d1\u8c7a\u7684\u57fa\u56e0\u9ad4\u4f5c\u4e86\u6bd4\u8f03\u3002<\/p>\n<p>\u4ed6\u5011\u767c\u73fe\uff0c\u548c\u72fc\u76f8\u6bd4\uff0c\u72d7\u7684\u57fa\u56e0\u9ad4\u4e2d\u78ba\u5be6\u542b\u6709\u8f03\u591a\u4e0d\u826f\u7a81\u8b8a\u3002\u4e0d\u904e\u751f\u6d3b\u5728\u8f03\u8207\u4e16\u9694\u7d55\u5730\u65b9\u7684\u72fc\uff0c\u4f8b\u5982\u7f8e\u570b\u4e94\u5927\u6e56\u88e1\u7684\u7687\u5bb6\u5cf6\u6216\u897f\u85cf\u5730\u5340\u7684\u72fc\uff0c\u57fa\u56e0\u9ad4\u5167\u7684\u4e0d\u826f\u7a81\u8b8a\u6578\u91cf\u4e5f\u4e0d\u9051\u591a\u8b93\u3002\u4ed6\u5011\u9084\u767c\u73fe\uff0c\u8207\u72fc\u76f8\u6bd4\uff0c\u72d7\u6709\u591a22\uff05\u5e36\u6709\u4e0d\u826f\u7a81\u8b8a\u7684\u57fa\u56e0\u662f\u540c\u578b\u5408\u5b50\uff0c\u7260\u5011\u5e73\u5747\u4e5f\u591a\u4e86115\u500b\u4e0d\u826f\u7a81\u8b8a\uff0c\u9019\u986f\u7136\u662f\u80b2\u7a2e\u6240\u9020\u6210\u7684\u526f\u4f5c\u7528\u3002\u9019\u500b\u7814\u7a76\u7d50\u679c\u767c\u8868\u5728\u300a\u7f8e\u570b\u570b\u5bb6\u79d1\u5b78\u9662\u9662\u520a\u300b\uff08<em>Proceedings of the National Academy of Sciences<\/em>\uff09\u3002<\/p>\n<p>\u9019\u500b\u7814\u7a76\u4e0d\u50c5\u80fd\u5920\u8b93\u6211\u5011\u77ad\u89e3\u99b4\u5316\u5c0d\u72d7\u72d7\u7684\u5f71\u97ff\uff0c\u4e5f\u80fd\u5920\u7528\u4f86\u63a2\u8a0e\u65cf\u7fa4\u6578\u6e1b\u5c11\u6216\u8fd1\u89aa\u7e41\u6b96\u5c0d\u5176\u4ed6\u52d5\u7269\uff0c\u4f8b\u5982\u5b64\u7acb\u7684\u7684\u65cf\u7fa4\u6216\u7015\u5371\u7684\u52d5\u7269\u4e4b\u5f71\u97ff\uff0c\u8b93\u4fdd\u80b2\u751f\u7269\u5b78\u5bb6\u7814\u8a0e\u51fa\u5c0d\u7b56\u4f86\u8b93\u7015\u5371\u52d5\u7269\u5728\u91ce\u5916\u6216\u5708\u990a\u6642\u4fdd\u6709\u9069\u7576\u65cf\u7fa4\u5927\u5c0f\u3002<\/p>\n<p><strong>\u539f\u5b78\u8853\u8ad6\u6587\uff1a<\/strong>Marsden CD, et al. Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs. PNAS, 2015. DOI: 10.1073\/pnas.1512501113<\/p>\n<p><strong>\u53c3\u8003\u8cc7\u6599\uff1a<\/strong><br \/>\n1. Cathleen O'Grady. <a href=\"http:\/\/arstechnica.com\/science\/2015\/12\/domestication-was-bad-news-for-doggy-dna\/\" target=\"_blank\" rel=\"noopener noreferrer\">Domestication was bad news for doggy DNA.<\/a> Ars Technica. Dec 23, 2015.<br \/>\n2. Karen Kaplan. <a href=\"http:\/\/www.latimes.com\/science\/sciencenow\/la-sci-sn-dog-domestication-harmful-dna-20151221-story.html\" target=\"_blank\" rel=\"noopener noreferrer\">Dog domestication saddled man's best friend with defective genes, study says. <\/a>Dec 29, 2015.<br \/>\n3. Sindya N. Bhanoo. <a href=\"http:\/\/www.nytimes.com\/2015\/12\/22\/science\/domesticated-dogs-lag-in-reproduction.html\" target=\"_blank\" rel=\"noopener noreferrer\">Domesticated Dogs Lag in Reproduction. <\/a>New York Times. Dec. 21, 2015.<\/p>\n<p><span style=\"color: #333399;\"><strong>--<\/strong><\/span><br style=\"color: #000000;\" \/><span style=\"color: #333399;\"><strong>\u4f5c\u8005\uff1a<strong>\u9ec3\u8c9e\u7965 \u73fe\u4efb\u6559\u65bc\u570b\u7acb\u6e05\u83ef\u5927\u5b78\u5206\u5b50\u8207\u7d30\u80de\u751f\u7269\u7814\u7a76\u6240\u66a8\u751f\u547d\u79d1\u5b78\u7cfb\uff0c<wbr \/>\u5f9e\u4e8b\u9ce5\u985e\u7684\u6f14\u5316\u907a\u50b3\u5b78\u3001\u57fa\u56e0\u9ad4\u5b78\u53ca\u6f14\u5316\u767c\u80b2\u751f\u7269\u5b78\u7814\u7a76\u3002<wbr \/>\u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b\uff0c\u5f9e\u4e8b\u79d1\u666e\u6587\u7ae0\u5beb\u4f5c\u3002<\/strong><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0\u72d7\u72d7\u7121\u7591\u662f\u4eba\u985e\u6700\u597d\u7684\u670b\u53cb\uff0c\u611b\u72d7\u7684\u4eba\u985e\u66f4<\/p>\n","protected":false},"author":20,"featured_media":23493,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,26,1025],"tags":[129,1765,93,2248],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/01\/2395724941_2b6908079a_b-640x425.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/23490"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23490"}],"version-history":[{"count":5,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/23490\/revisions"}],"predecessor-version":[{"id":32439,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/23490\/revisions\/32439"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/23493"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23490"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23490"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23490"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}