{"id":23427,"date":"2016-01-08T00:14:03","date_gmt":"2016-01-07T16:14:03","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=23427"},"modified":"2018-08-01T16:52:39","modified_gmt":"2018-08-01T08:52:39","slug":"%e3%80%90%e5%b9%b4%e5%ba%a6%e5%9b%9e%e9%a1%a7%e3%80%912015-%e5%b9%b4%e5%ba%a6%e7%a7%91%e5%ad%b8%e7%95%8c%e5%a4%a7%e4%ba%8b%e8%a8%98","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=23427","title":{"rendered":"\u3010\u5e74\u5ea6\u56de\u9867\u30112015 \u5e74\u5ea6\u79d1\u5b78\u754c\u5927\u4e8b\u8a18"},"content":{"rendered":"

\"2015\"<\/strong><\/span><\/p>\n

\u25a0\u6c23\u5019\u5cf0\u6703\u3001\u57fa\u56e0\u7de8\u8f2f\u3001\u9020\u8a2a\u51a5\u738b\u661f\u22ef\u22ef\u5c0d\u79d1\u5b78\u754c\u4f86\u8aaa\uff0c 2015 \u5e74\u6709\u8a31\u591a\u503c\u5f97\u8f09\u5165\u53f2\u518a\u7684\u5927\u4e8b\uff0c\u800c\u6211\u5011\u4e5f\u4e0d\u8981\u907a\u6f0f\u4e86\u90a3\u4e9b\u4ee4\u4eba\u8208\u596e\u7684\u79d1\u5b78\u65b0\u767c\u73fe\u3002<\/strong><\/span><\/p>\n

\u25cf\u5df4\u9ece\u5cf0\u6703\u7c3d\u8a02\u6c23\u5019\u5354\u8b70<\/strong><\/span><\/p>\n

\u5728 2015 \u5e74 12 \u6708\u65bc\u5df4\u9ece\u8209\u8fa6\u7684\u806f\u5408\u570b\u6c23\u5019\u5cf0\u6703\u4e0a\uff0c\u4e00\u5171 195 \u570b\u7c3d\u7f72\u5354\u8b70\uff0c\u5171\u540c\u8a93\u8a00\u6e1b\u6392\u6eab\u5ba4\u6c23\u9ad4\u3002\u9019\u500b\u4e16\u754c\u7e3d\u7b97\u7b2c\u4e00\u6b21\u5c0d\u6c23\u5019\u8b8a\u9077\u8a8d\u771f\u4ee5\u5f85\u3002<\/p>\n

\u5df4\u9ece\u5cf0\u6703\u5354\u8b70\u5c07\u6e1b\u6392\u76ee\u6a19\uff0c\u8a02\u5728\u7dad\u6301\u5168\u7403\u6696\u5316\u5728\u5347\u6eab\u651d\u6c0f\u5169\u5ea6\u4ee5\u5167\u3002\u5404\u570b\u5c07\u5728 2018 \u5e74\u5404\u81ea\u8a55\u4f30\u5176\u6e1b\u6392\u9032\u5ea6\uff0c\u4e26\u4e14\u5f9e 2020 \u5e74\u958b\u59cb\uff0c\u6bcf\u4e94\u5e74\u8981\u5b9a\u671f\u518d\u66f4\u65b0\u5176\u6e1b\u6392\u627f\u8afe\u3002\u4e2d\u570b\u8ddf\u7f8e\u570b\u9019\u4e16\u754c\u5169\u5927\u78b3\u6392\u653e\u570b\uff0c\u5728\u9019\u6b21\u90fd\u5c55\u73fe\u4e86\u4fc3\u6210\u5354\u8b70\u6210\u578b\u7684\u610f\u9858\uff1a\u4e2d\u570b\u5ba3\u4f48\u5c07\u63a8\u52d5\u78b3\u5c01\u5b58\u8207\u4ea4\u6613\u6a5f\u5236\uff0c\u7f8e\u570b\u7e3d\u7d71\u6b50\u5df4\u99ac\u4e5f\u7e3d\u7b97\u8c61\u5fb5\u6027\u5730\u5ba3\u4f48\uff0c\u62d2\u7d55\u5f9e\u52a0\u62ff\u5927\u9001\u6cb9\u5230\u7f8e\u570b\u7149\u6cb9\u5ee0\u7684\u300c\u57fa\u77f3 XL \u6cb9\u7ba1\u8a08\u756b\u300d (Keystone XL pipeline) \u3002\u5c31\u9023\u6559\u5b97\u65b9\u6fdf\u5404\u4e5f\u591a\u6b21\u8868\u9054\u5c0d\u6c23\u5019\u8b8a\u9077\u7684\u95dc\u5207\uff0c\u9593\u63a5\u5f71\u97ff\u4e86\u8f3f\u8ad6\u98a8\u5411\u3002<\/p>\n

\u4e0d\u904e\u96d6\u7136\u4eba\u5011\u6a02\u89c0\u5730\u8a8d\u70ba\uff0c\u9019\u6b21\u5cf0\u6703\u5c07\u6210\u70ba\u5c0d\u6297\u5168\u7403\u6696\u5316\u7684\u8f49\u6369\u9ede\uff0c\u7136\u800c\u6709\u9452\u65bc\u76ee\u524d\u7684\u5168\u7403\u5e73\u5747\u6eab\u5ea6\uff0c\u5df2\u7d93\u6bd4\u5de5\u696d\u6642\u4ee3\u524d\u9ad8\u51fa\u651d\u6c0f\u4e00\u5ea6\uff0c\u9019\u6b21\u5cf0\u6703\u7684\u76ee\u6a19\u6050\u6015\u7121\u6cd5\u5c07\u6696\u5316\u63a7\u5236\u5728\u6bd4\u5de5\u696d\u6642\u4ee3\u524d\u9ad8\u51fa\u651d\u6c0f\u5169\u5ea6\u4ee5\u5167\uff0c\u8a31\u591a\u79d1\u5b78\u5bb6\u8a8d\u70ba\u6211\u5011\u4ecd\u7136\u6703\u7e7c\u7e8c\u770b\u5230\u8a31\u591a\u8207\u6696\u5316\u6709\u95dc\u7684\u751f\u614b\u7570\u8c61\u3002<\/p>\n

\u25cf<\/strong>\u9020\u8a2a\u51a5\u738b\u661f<\/strong><\/span><\/p>\n

NASA \u7684\u300c\u65b0\u8996\u91ce\u865f\u300d\u5728 2015 \u5e74 7 \u6708 14 \u65e5\u98db\u63a0\u51a5\u738b\u661f\uff0c\u6210\u70ba\u4eba\u985e\u53f2\u4e0a\u7b2c\u4e00\u8258\u9020\u8a2a\u9019\u9846\u77ee\u884c\u661f\u7684\u592a\u7a7a\u8239\u3002\u5f9e\u300c\u65b0\u8996\u91ce\u865f\u300d\u56de\u50b3\u7684\u7167\u7247\u770b\u4f86\uff0c\u51a5\u738b\u661f\u662f\u4e00\u9846\u7531\u51b0\u5c71\u8108\u3001\u6c2e\u51b0\u6cb3\u8ddf\u8352\u6f20\u69cb\u6210\u7684\u5730\u8cea\u5947\u89c0\u661f\u7403\u3002\u9019\u53ef\u8b93\u884c\u661f\u79d1\u5b78\u5bb6\u5168\u90fd\u770b\u50bb\u4e86\u773c\uff0c\u4ed6\u5011\u7d1b\u7d1b\u63e3\u6e2c\u7a76\u7adf\u662f\u4ec0\u9ebc\u6a23\u7684\u529b\u91cf\uff0c\u9020\u5c31\u4e86\u5982\u6b64\u8c50\u5bcc\u7684\u5730\u8cea\u6d3b\u52d5\u3002<\/p>\n

NASA \u53e6\u4e00\u8258\u300c\u66d9\u5149\u865f\u300d\u592a\u7a7a\u8239\u5247\u662f\u5728 2015 \u5e74 3 \u6708\uff0c\u9020\u8a2a\u592a\u967d\u7cfb\u5167\u53e6\u4e00\u9846\u77ee\u884c\u661f\u300c\u7a40\u795e\u661f\u300d\u3002\u9019\u9846\u53ef\u80fd\u5bcc\u542b\u6c34\u7684\u6697\u6c88\u884c\u661f\u4e5f\u5f88\u795e\u79d8\uff0c\u4e0a\u982d\u6709\u91d1\u5b57\u5854\u72c0\u7684\u5c71\u8108\uff0c\u6703\u53cd\u5149\u7684\u9e7d\u9ede\uff0c\u4ee5\u53ca\u5728\u65e9\u6668\u967d\u5149\u4e0b\u7030\u6f2b\u9695\u77f3\u5751\u5167\u7684\u8b0e\u6a23\u9727\u973e\u3002<\/p>\n

\u25cf<\/strong>\u57fa\u56e0\u7de8\u8f2f\u65b9\u8208\u672a\u827e<\/strong><\/span><\/p>\n

\u5f88\u5c11\u6709\u4ec0\u9ebc\u7814\u7a76\u65b9\u6cd5\u50cf\u57fa\u56e0\u9ad4\u7de8\u8f2f\u6280\u8853 CRISPR-Cas9 \u9019\u6a23\uff0c\u5f15\u8d77\u83ab\u5927\u7684\u502b\u7406\u722d\u8b70\u3002\u4e2d\u570b\u79d1\u5b78\u5bb6\u5728 2015 \u5e74 4 \u6708\u5ba3\u4f48\uff0c\u4ed6\u5011\u7528\u9019\u5957\u6280\u6cd5\u7de8\u4fee\u4e86\u4e0d\u80fd\u751f\u80b2\u7684\u4eba\u985e\u80da\u80ce\u3002\u9019\u5728\u5b78\u754c\u5f15\u767c\u502b\u7406\u5b78\u7684\u5927\u8ad6\u6230\uff0c\u4e00\u76f4\u5ef6\u71d2\u5230 12 \u6708\u8209\u8fa6\u7684\u570b\u969b\u4eba\u985e\u57fa\u56e0\u7de8\u8f2f\u5cf0\u6703\uff0c\u8207\u6703\u4eba\u58eb\u6700\u5f8c\u767c\u8868\u8072\u660e\uff0c\u8a8d\u70ba\u57fa\u56e0\u7de8\u4fee\u6280\u8853\u76ee\u524d\u9084\u6c92\u6709\u6210\u719f\u5230\u53ef\u4ee5\u5c0d\u4eba\u985e\u80da\u80ce\u9032\u884c\u53d7\u5b55\u8655\u7406\u3002<\/p>\n

\u65e2\u6e96\u78ba\u53c8\u597d\u7528\u7684 CRISPR \u6280\u6cd5\uff0c\u5728\u904e\u53bb\u5e7e\u5e74\u5df2\u6210\u70ba\u79d1\u5b78\u5bb6\u7684\u6700\u611b\uff0c\u7528\u4f86\u5f37\u5316\u52d5\u690d\u7269\uff0c\u4e26\u5617\u8a66\u6cbb\u7642\u4eba\u985e\u75be\u75c5\u3002\u6709\u652f\u7814\u7a76\u5718\u968a\u7834\u8a18\u9304\u5730\u540c\u6642\u7de8\u8f2f 62 \u8655\u8c6c\u80da\u80ce\u57fa\u56e0\u9ad4\uff0c\u70ba\u7570\u7a2e\u751f\u7269\u5668\u5b98\u79fb\u690d\u91cd\u65b0\u958b\u555f\u4e00\u6247\u5927\u9580\uff1b\u53e6\u4e00\u652f\u7814\u7a76\u5718\u968a\u5247\u5728 Google \u7b49\u6295\u8cc7\u8005\u7684\u6339\u6ce8\u4e0b\uff0c\u6253\u7b97\u5728 2017 \u5e74\u9032\u884c CRISPR \u81e8\u5e8a\u8a66\u9a57\uff0c\u5617\u8a66\u77ef\u6b63\u8207\u8996\u529b\u53d7\u640d\u6709\u95dc\u7684\u7684\u57fa\u56e0\u7a81\u8b8a\u3002\u6709\u4e9b\u6bd4\u8f03\u6210\u719f\u7684\u57fa\u56e0\u9ad4\u7de8\u4fee\u6280\u8853\uff0c\u751a\u81f3\u5df2\u7d93\u958b\u59cb\u5728\u81e8\u5e8a\u4e0a\u8a66\u7528\u3002<\/p>\n

\u25cf<\/strong>\u75ab\u82d7\u958b\u767c\u5927\u6709\u65ac\u7372<\/strong><\/span><\/p>\n

\u4f0a\u6ce2\u62c9\u75c5\u6bd2\u75ab\u82d7 rVSV-ZEBOV \u5728 2015 \u5e74 4 \u6708\uff0c\u65bc\u5e7e\u5167\u4e9e\u9032\u884c\u81e8\u5e8a\u8a66\u9a57\uff0c\u521d\u6b65\u5206\u6790\u7d50\u679c\u986f\u793a\u53ea\u8981\u5728\u63a5\u89f8\u75c5\u6bd2\u5f8c\u7acb\u523b\u65bd\u6253\uff0c\u5c31\u53ef\u4ee5\u63d0\u4f9b\u5e7e\u8fd1\u5b8c\u5168\u7684\u4fdd\u8b77\u4f5c\u7528\u3002\u53ef\u60dc\u9019\u500b\u75ab\u82d7\u4f86\u7684\u6709\u9ede\u70ba\u6642\u5df2\u665a\uff0c\u672a\u80fd\u5c0d\u4eca\u5e74\u8086\u8650\u897f\u975e\u5730\u5340\u7684\u4f0a\u6ce2\u62c9\u75ab\u60c5\u9020\u6210\u591a\u5927\u5f71\u97ff\u3002<\/p>\n

\u5728\u7d93\u904e\u5c07\u8fd1 30 \u5e74\u7684\u7814\u767c\u4e4b\u5f8c\uff0c\u5168\u4e16\u754c\u7b2c\u4e00\u652f\u7627\u75be\u75ab\u82d7\u65bc 2015 \u5e74\u554f\u4e16\uff0c\u65bc 1 \u842c 5000 \u591a\u540d\u975e\u6d32\u5152\u7ae5\u8eab\u4e0a\u9032\u884c\u81e8\u5e8a\u8a66\u9a57\u4e4b\u5f8c\uff0c\u9054\u5230\u5927\u7d04 30% \u7684\u4fdd\u8b77\u7387\u3002<\/p>\n

\u5c0f\u5152\u75f2\u75f9\u75ab\u82d7\u5247\u4f7f\u5f97\u9019\u7a2e\u8870\u9000\u6027\u75be\u75c5\uff0c\u5728\u5168\u4e16\u754c\u5e7e\u8fd1\u7d55\u8de1\uff0c 2015 \u5e74\u5168\u7403\u50c5\u56de\u5831 66 \u8d77\u75c5\u4f8b\u3002\u5948\u53ca\u5229\u4e9e\u4eca\u5e74\u9996\u5ea6\u6574\u5e74\u90fd\u6c92\u6709\u5c0f\u5152\u75f2\u75f9\u75c5\u4f8b\uff0c\u4e16\u754c\u885b\u751f\u7d44\u7e54\u5c07\u5b83\u5f9e\u5c0f\u5152\u75f2\u75f9\u6d41\u884c\u570b\u5bb6\u540d\u55ae\u4e2d\u522a\u9664\uff0c\u975e\u6d32\u56e0\u6b64\u6709\u671b\u5728 2017 \u5e74\u5ba3\u4f48\u5c0f\u5152\u75f2\u75f9\u7d55\u8de1\u3002<\/p>\n

\u25cf<\/strong>\u91cf\u5b50\u7e8f\u7d50\u65b0\u8b49\u64da<\/strong><\/span><\/p>\n

\u7269\u7406\u5b78\u5bb6\u4eca\u5e74\u8209\u8fa6\u4e86\u4e0d\u5c11\u7814\u8a0e\u6703\uff0c\u6176\u795d\u611b\u56e0\u65af\u5766\u767c\u8868\u5ee3\u7fa9\u76f8\u5c0d\u8ad6\u4e00\u767e\u9031\u5e74\u3002\u4ed6\u5011\u4e5f\u767c\u8868\u8fc4\u4eca\u6700\u5177\u6709\u8aaa\u670d\u529b\u7684\u8b49\u64da\uff0c\u6307\u51fa\u5169\u500b\u91cf\u5b50\u78ba\u5be6\u6709\u300c\u7e8f\u7d50\u300d\u73fe\u8c61\uff0c\u56e0\u6b64\u5b83\u5011\u5373\u4f7f\u76f8\u9694\u751a\u9060\uff0c\u4e5f\u80fd\u5f7c\u6b64\u5f71\u97ff\u5c0d\u65b9\u3002\u611b\u56e0\u65af\u5766\u662f\u51fa\u4e86\u540d\u5730\u53cd\u5c0d\u91cf\u5b50\u8ad6\uff0c\u56e0\u70ba\u9019\u4f3c\u4e4e\u9055\u53cd\u4e86\u6c92\u6709\u6771\u897f\u80fd\u5920\u8d85\u8d8a\u5149\u901f\u7684\u5b87\u5b99\u5b9a\u5f8b\uff1b\u4e0d\u904e\u8981\u662f\u611b\u56e0\u65af\u5766\u641e\u932f\u4e86\uff0c\u6211\u5011\u4e5f\u8a31\u6709\u671d\u4e00\u65e5\uff0c\u5c31\u80fd\u5920\u64c1\u6709\u514d\u53d7\u99ed\u5ba2\u653b\u64ca\u7684\u91cf\u5b50\u7db2\u969b\u7db2\u8def\u3002<\/p>\n

\u25cf<\/strong>\u77f3\u6cb9\u696d\u7684\u4eba\u9020\u5730\u9707<\/strong><\/span><\/p>\n

\u63a2\u52d8\u77f3\u6cb9\u8207\u5929\u7136\u6c23\u7b49\u4eba\u985e\u6d3b\u52d5\uff0c\u5728\u4e16\u754c\u5404\u5730\u90fd\u6703\u5f15\u767c\u5730\u9707\u3002\u7f8e\u570b\u5967\u514b\u62c9\u8377\u99ac\u5dde\u5f9e 2009 \u5e74\u958b\u59cb\uff0c\u5c31\u767c\u73fe\u5730\u9707\u6d3b\u52d5\u9010\u5e74\u589e\u52a0\uff0c\u4eca\u5e74\u82ae\u6c0f\u898f\u6a21 3 \u4ee5\u4e0a\u7684\u5730\u9707\u6b21\u6578\uff0c\u66f4\u662f\u8d85\u8d8a\u52a0\u5dde\u3002\u5967\u514b\u62c9\u8377\u99ac\u5730\u8cea\u8abf\u67e5\u5c0f\u7d44\u5728 2015 \u5e74 4 \u6708\u767c\u8868\u5831\u544a\uff0c\u6307\u51fa\u77f3\u6cb9\u516c\u53f8\u5c07\u6578\u5343\u842c\u516c\u5347\u7684\u5ee2\u6c34\u6ce8\u5165\u5730\u5e95\u6df1\u8655\uff0c\u6539\u8b8a\u4e86\u65b7\u5c64\u58d3\u529b\uff0c\u53ef\u80fd\u662f\u5c0e\u81f4\u5730\u9707\u983b\u4ecd\u7684\u4e3b\u56e0\u3002<\/p>\n

\u7576\u5730\u8ca0\u8cac\u63a7\u7ba1\u77f3\u6cb9\u8207\u5929\u7136\u6c23\u63a2\u52d8\u7684\u4f01\u696d\u59d4\u54e1\u6703\uff0c\u524a\u6e1b\u5728\u5730\u9707\u6d3b\u52d5\u6700\u983b\u7e41\u5340\u57df\u7684\u5ee2\u6c34\u68c4\u7f6e\u4e95\u6578\u91cf\uff0c\u4ee5\u505a\u70ba\u56de\u61c9\u3002\u4ee5\u80fd\u6e90\u696d\u8005\u5728\u7576\u5730\u7684\u5f37\u52e2\u800c\u8ad6\uff0c\u6b64\u8209\u7b97\u662f\u633a\u4e86\u4e0d\u8d77\u7684\u3002<\/p>\n

\u25cf<\/strong>\u63d0\u5347\u7814\u7a76\u53ef\u4fe1\u5ea6<\/strong><\/span><\/p>\n

\u7814\u7a76\u7d50\u679c\u96e3\u4ee5\u8907\u88fd\u7684\u539f\u56e0\u5f88\u591a\uff0c\u6709\u4e9b\u662f\u7814\u7a76\u65b9\u6cd5\u6839\u672c\u6c92\u8aaa\u6e05\u695a\uff0c\u6709\u4e9b\u5247\u662f\u8cc7\u6599\u5206\u6790\u6709\u7455\u75b5\u3002\u6709\u7814\u7a76\u8a08\u756b\u5617\u8a66\u5c0d\u5fc3\u7406\u5b78\u7814\u7a76\u7d50\u679c\u9032\u884c\u8907\u88fd\uff0c\u7d50\u679c\u5931\u6557\u7387\u9ad8\u9054\u4e09\u5206\u4e4b\u4e8c\u3002\u6839\u64da\u53e6\u4e00\u9805\u7814\u7a76\u4f30\u8a08\uff0c\u6bcf\u5e74\u6709 280 \u5104\u7f8e\u5143\u7684\u8cc7\u91d1\uff0c\u82b1\u5728\u7814\u7a76\u7d50\u679c\u7121\u6cd5\u8907\u88fd\u7684\u751f\u91ab\u7814\u7a76\u4e0a\u982d\u3002<\/p>\n

\u7d66\u9322\u7684\u55ae\u4f4d\u7d42\u65bc\u6c7a\u5fc3\u4e0d\u518d\u505a\u51a4\u5927\u982d\u3002\u82f1\u570b\u7684\u885b\u723e\u5eb7\u57fa\u91d1\u6703\u5728 2015 \u5e74\u63d0\u51fa\u5177\u9ad4\u7b56\u7565\uff0c\u8981\u5c07\u5be6\u9a57\u6d41\u7a0b\u6a19\u6e96\u5316\uff0c\u85c9\u6b64\u6539\u5584\u7814\u7a76\u7684\u53ef\u8907\u88fd\u6027\u3002\u7f8e\u570b\u570b\u5bb6\u885b\u751f\u9662\u5728 2015 \u5e74 10 \u6708\uff0c\u516c\u4f48\u7814\u7a76\u53ef\u8907\u88fd\u6027\u7684\u6307\u5c0e\u539f\u5247\uff0c\u8981\u6c42\u88dc\u52a9\u91d1\u5be9\u67e5\u54e1\u7559\u610f\u5be6\u9a57\u8a2d\u8a08\u662f\u5426\u6709\u6703\u9020\u6210\u504f\u8aa4\u7684\u7f3a\u9677\uff0c\u4e26\u8981\u6c42\u88dc\u52a9\u91d1\u7533\u8acb\u8005\u63d0\u51fa\u5982\u4f55\u7cfe\u6b63\u7684\u5177\u9ad4\u8fa6\u6cd5\u3002\u4e0d\u904e\u5b78\u8853\u754c\u5c0d\u6b64\u4e0d\u592a\u9ad8\u8208\uff0c\u6709\u4e9b\u5b78\u6703\u8868\u793a\u9019\u4e9b\u7d19\u4e0a\u4f5c\u696d\u6703\u589e\u52a0\u4ed6\u5011\u5beb\u8ad6\u6587\u7684\u8ca0\u64d4\u3002<\/p>\n

\u25cf<\/strong>\u6027\u5225\u6b67\u8996\u8b70\u984c\u71b1<\/strong><\/span><\/p>\n

\u79d1\u5b78\u754c\u5728 2015 \u5e74\u7206\u51fa\u4e86\u597d\u5e7e\u689d\u5169\u6027\u65b0\u805e\uff0c\u986f\u793a\u6c99\u6587\u4e3b\u7fa9\u5728\u8c61\u7259\u5854\u4e2d\u4ecd\u7136\u5341\u5206\u7316\u7357\u3002\u82f1\u570b\u85a9\u585e\u514b\u65af\u5927\u5b78\u6f14\u5316\u907a\u50b3\u5b78\u5bb6\u83f2\u6b50\u5a1c\uff0e\u82f1\u683c\u7435 (Fiona Ingleby) \u5728 4 \u6708\u65bc\u63a8\u7279\u4e0a\u7206\u6599\uff0c\u8aaa\u5979\u8ddf\u53e6\u4e00\u4f4d\u5973\u6027\u540c\u4e8b\u806f\u540d\u7684\u8ad6\u6587\u88ab\u300a PLoS ONE \u300b\u9000\u4ef6\uff0c\u7406\u7531\u662f\u6709\u540d\u5be9\u67e5\u59d4\u54e1\u8aaa\u300c\u52a0\u4e0a\u4e00\u5169\u540d\u7537\u6027\u7684\u5171\u540c\u4f5c\u8005\uff0c\u53ef\u4ee5\u6539\u5584\u5206\u6790\u7d50\u679c\u300d\u3002\u300a PLoS ONE \u300b\u628a\u8a72\u540d\u5be9\u67e5\u59d4\u54e1\u5f9e\u8cc7\u6599\u5eab\u9664\u540d\uff0c\u4e26\u8981\u6c42\u8ca0\u8cac\u5be9\u67e5\u9019\u7bc7\u8ad6\u6587\u7684\u5b78\u8853\u7de8\u8f2f\u9000\u51fa\u5be9\u67e5\u5c0f\u7d44\u3002<\/p>\n

\u7dca\u63a5\u8457\u5728 6 \u6708\uff0c\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u63d0\u59c6\uff0e\u676d\u7279 (Tim Hunt) \u653e\u8a71\u8aaa\u4ed6\u8ddf\u5be6\u9a57\u5ba4\u88e1\u7684\u5973\u751f\u8655\u4e0d\u4f86\u3002\u300c\u4f60\u611b\u4e0a\u5979\u5011\uff0c\u5979\u5011\u611b\u4e0a\u4f60\uff0c\u7136\u5f8c\u4f60\u8072\u97f3\u4e00\u5927\u8d77\u4f86\uff0c\u5979\u5011\u5c31\u54ed\u7d66\u4f60\u770b\u3002\u300d\u4ed6\u904e\u5169\u5929\u5c31\u88ab\u8feb\u8fad\u53bb\u502b\u6566\u5927\u5b78\u5b78\u9662\u69ae\u8b7d\u6559\u6388\u4e00\u8077\uff0c\u8aaa\u4ed6\u53ea\u662f\u60f3\u628a\u6c23\u6c1b\u641e\u5f97\u8f15\u9b06\u9ede\uff0c\u537b\u88ab\u540a\u6b7b\u793a\u773e\u3002<\/p>\n

\u6700\u5927\u689d\u7684\u65b0\u805e\u5728 10 \u6708\u7206\u51fa\u4f86\uff1a\u8457\u540d\u7cfb\u5916\u884c\u661f\u5c08\u5bb6\u5409\u5967\u592b\uff0e\u99ac\u897f (Geoffrey Marcy) \uff0c\u6d89\u5acc\u5728\u904e\u53bb\u5341\u591a\u5e74\u9593\uff0c\u5c0d\u597d\u5e7e\u540d\u5b78\u751f\u6027\u9a37\u64fe\u3002\u99ac\u897f\u6700\u5f8c\u5728\u5929\u6587\u5b78\u754c\u7684\u6ed4\u5929\u4e4b\u6012\u4e2d\uff0c\u8fad\u53bb\u4e86\u4ed6\u5728\u52a0\u5dde\u5927\u5b78\u67cf\u514b\u840a\u5206\u6821\u7684\u6559\u8077\u3002\u9019\u500b\u6848\u4f8b\u5f15\u8d77\u5b78\u8853\u754c\u91cd\u65b0\u8a55\u4f30\u73fe\u884c\u653f\u7b56\uff0c\u5e0c\u671b\u80fd\u9632\u6b62\u6027\u9a37\u64fe\u4e8b\u4ef6\u7e7c\u7e8c\u767c\u751f\u3002<\/p>\n

\u25cf<\/strong>\u5206\u5b50\u7d50\u69cb\u5927\u63ed\u79d8<\/strong><\/span><\/p>\n

\u7d50\u69cb\u751f\u7269\u5b78\u5bb6\u5229\u7528\u4f4e\u6eab\u96fb\u5b50\u986f\u5fae\u6280\u8853 (cryo-EM) \uff0c\u4ee5\u524d\u6240\u672a\u898b\u7684\u7cbe\u7d30\u7a0b\u5ea6\uff0c\u63ed\u9732\u751f\u7269\u7684\u5206\u5b50\u6a5f\u5236\u3002\u7814\u7a76\u8005\u5148\u5c07\u7d30\u80de\u86cb\u767d\u8cea\u7684\u7d50\u69cb\u300c\u51cd\u7d50\u300d\u8d77\u4f86\uff0c\u518d\u7528\u96fb\u5b50\u986f\u5fae\u93e1\u5e7e\u8fd1\u539f\u5b50\u7684\u89e3\u6790\u5ea6\u52a0\u4ee5\u62cd\u651d\u7814\u7a76\u3002\u751f\u7269\u5b78\u5bb6\u85c9\u7531\u9019\u9805\u6280\u8853\uff0c\u5728 2015 \u5e74\u5df2\u7e6a\u51fa\u4e00\u767e\u591a\u7a2e\u5206\u5b50\u7d50\u69cb\uff0c\u5176\u4e2d\u5305\u62ec\u56de\u6536\u640d\u58de\u86cb\u767d\u8cea\u7684\u86cb\u767d\u9176\u9ad4\uff0c\u4ee5\u53ca\u5728 mRNA \u8f49\u8b6f\u6210\u86cb\u767d\u8cea\u4e4b\u524d\u5c07\u5b83\u5207\u788e\u7684\u526a\u63a5\u9ad4\u3002\u4eca\u5929\u4ed6\u5011\u5e0c\u671b\u80fd\u5920\u85c9\u6b64\u5229\u5668\uff0c\u7e6a\u51fa\u66f4\u591a\u8207\u91ab\u7642\u6709\u95dc\u7684\u91cd\u8981\u5206\u5b50\u771f\u9762\u8c8c\u3002<\/p>\n

\u25cf<\/strong>\u7cbe\u6e96\u91ab\u7642\u555f\u52d5<\/strong><\/span><\/p>\n

\u70ba\u75c5\u4eba\u91cf\u8eab\u5b9a\u505a\u7642\u7a0b\uff0c\u4e00\u76f4\u662f\u751f\u7269\u91ab\u5b78\u7684\u91cd\u8981\u76ee\u6a19\u3002\u7f8e\u570b\u7e3d\u7d71\u6b50\u5df4\u99ac\u5728 2015 \u5e74 1 \u6708\uff0c\u5ba3\u4f48\u65a5\u8cc7 2 \u5104 1500 \u842c\u7f8e\u5143\uff0c\u63a8\u52d5\u300c\u7cbe\u6e96\u91ab\u7642\u65b9\u6848\u300d (PMI) \uff0c\u8ca0\u8cac\u57f7\u884c\u7684\u7f8e\u570b\u570b\u5bb6\u885b\u751f\u9662\u5c07\u62db\u52df\u4e00\u767e\u842c\u4eba\uff0c\u6536\u96c6\u4ed6\u5011\u7684\u907a\u50b3\u8cc7\u8a0a\u53ca\u75c5\u6b77\uff0c\u751a\u81f3\u6703\u900f\u904e\u96fb\u5b50\u76e3\u63a7\u88dd\u7f6e\u6536\u96c6\u8cc7\u6599\uff0c\u63d0\u4f9b\u7814\u7a76\u8005\u9032\u884c\u76f8\u95dc\u7814\u7a76\u3002\u52a0\u62ff\u5927\u8ddf\u4e2d\u570b\u53d7\u6b64\u6fc0\u52f5\uff0c\u4e5f\u5404\u81ea\u8457\u624b\u63a8\u52d5\u985e\u4f3c\u8a08\u756b\u3002<\/p>\n

--<\/strong>
\n\u672c\u6587\u7531\u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b \u9ad8\u82f1\u54f2\u7de8\u8b6f\u3002
\n\u7de8\u8b6f\u4f86\u6e90\uff1a<\/strong>The science events that shaped 2015<\/a><\/p>\n

 <\/p>\n

\"\u52a0\u5165\u597d\u53cb\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\u25a0\u6c23\u5019\u5cf0\u6703\u3001\u57fa\u56e0\u7de8\u8f2f\u3001\u9020\u8a2a\u51a5\u738b\u661f\u22ef\u22ef\u5c0d\u79d1<\/p>\n","protected":false},"author":20,"featured_media":23496,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1027,3293],"tags":[],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2016\/01\/20151.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/23427"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23427"}],"version-history":[{"count":8,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/23427\/revisions"}],"predecessor-version":[{"id":32448,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/23427\/revisions\/32448"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/23496"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23427"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23427"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23427"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}