{"id":22747,"date":"2015-11-03T00:19:05","date_gmt":"2015-11-02T16:19:05","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=22747"},"modified":"2018-08-01T16:31:19","modified_gmt":"2018-08-01T08:31:19","slug":"%e3%80%90%e7%94%9f%e6%b4%bb%e5%8c%96%e5%ad%b8%e3%80%91%e9%98%b2%e6%9b%ac%e4%b9%b3%e7%a7%91%e5%ad%b8%ef%bc%9a%e6%98%af%e4%bf%9d%e8%ad%b7%e9%82%84%e6%98%af%e5%8f%a6%e4%b8%80%e7%a8%ae%e5%82%b7%e5%ae%b3","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=22747","title":{"rendered":"\u3010\u751f\u6d3b\u5316\u5b78\u3011\u9632\u66ec\u4e73\u79d1\u5b78\uff1a\u662f\u4fdd\u8b77\u9084\u662f\u53e6\u4e00\u7a2e\u50b7\u5bb3\uff1f"},"content":{"rendered":"

\u25a0\u9632\u66ec\u4e73\u56fa\u7136\u53ef\u4ee5\u4fdd\u8b77\u6211\u5011\u514d\u65bc\u53d7\u5230\u7d2b\u5916\u7dda\u7684\u7167\u5c04\uff0c\u4f46\u672c\u8eab\u7684\u6bd2\u6027\u8981\u600e\u9ebc\u907f\u514d\u5462\uff1f<\/strong><\/span><\/p>\n

\"its-always-sunny-sunscreen-flask-640x533\"
http:\/\/www.thisiswhyimbroke.com\/sunscreen-bottle-flask<\/figcaption><\/figure>\n

\u64b0\u6587\uff5c<\/strong>\u65b9\u7a0b\u6bc5<\/p>\n

\u4e0d\u7ba1\u662f\u70ba\u4e86\u7f8e\u767d\u9084\u662f\u5065\u5eb7\uff0c\u5f88\u591a\u4eba\u5230\u4e86\u6236\u5916\u5c31\u4e00\u5b9a\u6703\u5857\u4e0a\u539a\u539a\u7684\u9632\u66ec\u4e73\uff0c\u9632\u6b62\u7d2b\u5916\u7dda\u50b7\u5bb3\u76ae\u819a\u3002\u64e6\u4e86\u9632\u66ec\u4e73\u7576\u7136\u53ef\u6709\u6548\u964d\u4f4e\u76ae\u819a\u53d7\u5230\u7d2b\u5916\u7dda\u7684\u50b7\u5bb3\uff0c\u4f46\u4f60\u6709\u6c92\u6709\u60f3\u904e\uff0c\u9632\u66ec\u4e73\u9019\u500b\u7269\u8cea\u672c\u8eab\u5c31\u6703\u5c0d\u4eba\u9ad4\u9020\u6210\u5f71\u97ff\u5462\uff1f<\/p>\n

\u4e00\u822c\u4f86\u8aaa\uff0c\u9632\u66ec\u4e73\u662f\u9760\u4e00\u4e9b\u6703\u5438\u6536\u7d2b\u5916\u5149\u7684\u6709\u6a5f\u5206\u5b50\u6563\u4f48\u5728\u6cb9\u8102\u6216\u6c34\u7684\u4e73\u72c0\u7269\u88e1\uff0c\u7d2b\u5916\u7dda\u5728\u78b0\u5230\u76ae\u819a\u524d\u5c31\u6703\u88ab\u9019\u4e9b\u5206\u5b50\u5438\u6536\uff0c\u4fdd\u8b77\u76ae\u819a\u514d\u65bc\u53d7\u5230\u50b7\u5bb3\u3002\u9019\u4e9b\u6709\u6a5f\u5206\u5b50\u8209\u4f8b\u4f86\u8aaa\u6709\uff1avobenzone\u3001octinoxate\u3001padimate O\uff0c\u96d6\u7136\u82f1\u6587\u770b\u8d77\u4f86\u6df1\u6f80\u96e3\u61c2\uff0c\u4f46\u91cd\u9ede\u662f\u9019\u4e9b\u90fd\u662f\u542b\u6709\u82ef\u74b0\u7684\u6709\u6a5f\u7269\uff0c\u6709\u9ede\u57fa\u672c\u5316\u5b78\u5e38\u8b58\u7684\u4eba\u90fd\u77e5\u9053\u9019\u7d55\u5c0d\u4e0d\u662f\u4ec0\u9ebc\u597d\u6771\u897f\uff0c\u56e0\u6b64\u9019\u4e9b\u6709\u6a5f\u7269\u96d6\u7136\u80fd\u6210\u529f\u4fdd\u8b77\u76ae\u819a\u514d\u65bc\u53d7\u5230\u7d2b\u5916\u5149\u66dd\u66ec\uff0c\u4f46\u672c\u8eab\u7684\u6bd2\u6027\u6211\u5011\u537b\u7121\u6cd5\u907f\u514d\u3002\u6839\u64da\u7814\u7a76\u986f\u793a\uff0c\u9632\u66ec\u4e73\u7684\u6709\u6a5f\u6210\u5206\u53ef\u4ee5\u7a7f\u904e\u89d2\u8cea\u5c64\uff0c\u9032\u5230\u8868\u76ae\u751a\u81f3\u771f\u76ae\u5c64\uff0c\u66f4\u5728\u4eba\u985e\u7684\u8840\u6db2\u3001\u5c3f\u6db2\u4ee5\u53ca\u6bcd\u4e73\u4e2d\u88ab\u767c\u73fe\uff0c\u4e5f\u5c31\u662f\u8aaa\u9019\u4e9b\u7269\u8cea\u6703\u9032\u5165\u5230\u6211\u5011\u7684\u5faa\u74b0\u7cfb\u7d71\uff0c\u96e3\u4ee5\u4ee3\u8b1d\u3002\u4e0d\u50c5\u9019\u4e9b\u7269\u8cea\u672c\u8eab\u6703\u6b98\u7559\uff0c\u7576\u5b83\u5011\u5438\u6536\u7d2b\u5916\u7dda\u5f8c\u7522\u751f\u7684\u526f\u7522\u7269\u6d3b\u6027\u6c27\u5316\u7269(Reactive oxygen species \uff0c\u4e5f\u5c31\u662f\u81ea\u7531\u57fa)\uff0c\u6703\u5c0d\u7d30\u80de\u9020\u6210\u5de8\u5927\u50b7\u5bb3\uff0c\u56e0\u6b64\u9632\u66ec\u4e73\u96d6\u7136\u9632\u66ec\uff0c\u4f46\u5f8c\u7e8c\u9020\u6210\u7684\u5371\u5bb3\u537b\u4e0d\u5f97\u4e0d\u9632\u3002<\/p>\n

\u7f8e\u570b\u8036\u9b6f\u5927\u5b78\u751f\u7269\u91ab\u5b78\u5de5\u7a0b\u7cfbMark Saltzman\u6559\u6388\u7684\u5be6\u9a57\u5ba4\u6700\u8fd1\u7814\u767c\u51fa\u4e00\u7a2e\u65b0\u65b9\u6cd5\u89e3\u6c7a\u9019\u500b\u554f\u984c\u3002\u4ed6\u5011\u628a\u9019\u4e9b\u53ef\u4ee5\u5438\u6536\u7d2b\u5916\u5149\u7684\u6709\u6a5f\u7269\u300c\u5305\u300d\u5728\u4e00\u500b\u7c92\u5b50\u88e1\u9762\uff0c\u9019\u7a2e\u7c92\u5b50\u4e0d\u6703\u7a7f\u904e\u89d2\u8cea\u5c64\u9032\u5230\u76ae\u819a\u6216\u5faa\u74b0\u7cfb\u7d71\u88e1\u9762\uff0c\u540c\u6642\u53c8\u80fd\u8b93\u9019\u4e9b\u6709\u6a5f\u7269\u4fdd\u6709\u5438\u6536\u7d2b\u5916\u5149\u7684\u80fd\u529b\uff0c\u66f4\u53ef\u4ee5\u628a\u5438\u6536\u7d2b\u5916\u5149\u5f8c\u7522\u751f\u7684\u6d3b\u6027\u6c27\u5316\u7269\u95dc\u5728\u88e1\u9762\uff0c\u8b93\u7d30\u80de\u514d\u65bc\u53d7\u5230\u653b\u64ca\u3002\u9019\u9805\u7814\u7a76\u88ab\u520a\u767b\u57282015\u5e74\u300a\u81ea\u7136\u2027\u6750\u6599\u300b\u671f\u520a(Nature Materials<\/em>)\uff0c\u4e26\u7372\u5f97\u300aPhys.Org\u300b\u7db2\u7ad9\u5831\u5c0e\u3002<\/p>\n

\u65e2\u7136\u8981\u628a\u6709\u6a5f\u7269\u5305\u5728\u4e00\u500b\u7c92\u5b50\u88e1\uff0c\u5c31\u8981\u78ba\u4fdd\u9019\u500b\u7c92\u5b50\u80fd\u5920\u7559\u5728\u76ae\u819a\u4e0a\uff0c\u5177\u6709\u751f\u7269\u9ecf\u9644\u6027(bioadhesive)\uff0c\u5426\u5247\u4e00\u4e0b\u5c31\u812b\u843d\u4fbf\u5b8c\u5168\u6c92\u6709\u9632\u66ec\u6548\u679c\uff0c\u540c\u6642\u4e5f\u8981\u4fdd\u8b49\u5b83\u5011\u4e0d\u6703\u9032\u5165\u5230\u8eab\u9ad4\u88e1\u3002\u8036\u9b6f\u5927\u5b78\u7814\u7a76\u5718\u968a\u4f7f\u7528\u7684\u7c92\u5b50\u70baPLA-HPG (polylactic acid-hyperbranched polyglycerol)\uff0c\u9019\u5728\u91ab\u5b78\u4e0a\u662f\u4e00\u7a2e\u53ef\u4ee5\u628a\u85e5\u7269\u5305\u4f4f\u4e26\u9001\u5230\u816b\u7624\u7684\u5948\u7c73\u7c92\u5b50\uff0c\u65e2\u7136\u90fd\u53ef\u4ee5\u9001\u85e5\u7269\uff0c\u5305\u8986\u5438\u6536\u7d2b\u5916\u5149\u7684\u6709\u6a5f\u7269\u7576\u7136\u6c92\u6709\u554f\u984c\uff0c\u4f46\u662fPLA-HPG\u537b\u4e0d\u5177\u6709\u751f\u7269\u9ecf\u9644\u6027\uff0c\u7121\u6cd5\u9577\u6642\u9593\u505c\u7559\u5728\u76ae\u819a\u8868\u9762\uff0c\u56e0\u6b64\u5fc5\u9808\u5c0d\u8868\u9762\u505a\u4fee\u98fe\uff0c\u8b93\u7c92\u5b50\u8868\u9762\u5e36\u6709\u5bb9\u6613\u8ddf\u86cb\u767d\u8cea\u9023\u63a5\u7684\u919b\u57fa\u3002\u9019\u500b\u5e36\u6709\u919b\u57fa\u7684\u7c92\u5b50\u65e2\u53ef\u4ee5\u628a\u5438\u6536\u7d2b\u5916\u5149\u7684\u6709\u6a5f\u7269\u5305\u5728\u88e1\u9762\uff0c\u53c8\u53ef\u4ee5\u9577\u6642\u9593\u9644\u8457\u5728\u76ae\u819a\u8868\u9762\uff0c\u6240\u4ee5\u4e5f\u4e0d\u9700\u8981\u4e00\u76f4\u88dc\u5857\u3002\u6839\u64da\u5be6\u9a57\u986f\u793a\uff0c\u88ab\u7c92\u5b50\u5305\u8986\u7684\u9632\u66ec\u7269\u5857\u62b9\u5728\u8001\u9f20\u76ae\u819a\u8868\u9762\u4e94\u5929\u4e4b\u5f8c\uff0c\u90fd\u6c92\u6709\u5165\u4fb5\u5230\u8868\u76ae\u53ca\u771f\u76ae\u5c64\u3002\u66f4\u91cd\u8981\u7684\u662f\u53ea\u8981\u7528\u6fd5\u5e03\u5728\u76ae\u819a\u4e0a\u64e6\u62ed\uff0c\u9019\u4e9b\u7c92\u5b50\u5c31\u53ef\u4ee5\u88ab\u64e6\u6389\uff0c\u4e0d\u56e0\u70ba\u5177\u6709\u751f\u7269\u4f9d\u9644\u6027\u5c31\u96e3\u4ee5\u6e05\u7406\uff0c\u5c31\u7b97\u4e0d\u7279\u5225\u53bb\u6e05\u7406\u4e5f\u6703\u96a8\u8457\u89d2\u8cea\u5c64\u7684\u65b0\u9673\u4ee3\u8b1d\u800c\u812b\u843d\u3002<\/p>\n

\"\u751f\u7269\u5438\u9644\u6027\u5948\u7c73\u7c92\u5b50\u793a\u610f\u5716\u3002(a)\u967d\u5149\u7167\u5c04\u524d<\/a>
\u751f\u7269\u5438\u9644\u6027\u5948\u7c73\u7c92\u5b50\u793a\u610f\u5716\u3002(a)\u967d\u5149\u7167\u5c04\u524d (b)\u967d\u5149\u7167\u5c04\u6642 (c)\u967d\u5149\u7167\u5c04\u5f8c\u3002
UV filter\uff1a\u5438\u6536\u7d2b\u5916\u5149\u7684\u5206\u5b50\u3001ROS from UV filter\uff1a\u5206\u5b50\u5438\u6536\u7d2b\u5916\u5149\u5f8c\u7522\u751f\u7684\u6d3b\u6027\u6c27\u5316\u7269\u3001Nanoparticle\uff1a\u751f\u7269\u5438\u9644\u6027\u5948\u7c73\u7c92\u5b50\u3001Anti-UV protection\uff1a\u80fd\u6709\u6548\u5438\u6536\u7d2b\u5916\u5149\u7684\u5340\u57df\u3001Stratum corneum\uff1a\u89d2\u8cea\u5c64\u3001Epidermis and dermis\uff1a\u8868\u76ae\u5c64\u53ca\u771f\u76ae\u5c64\u3001Sunscreen\uff1a\u4e00\u822c\u9632\u66ec\u4e73\u3001BNPs\/UV filters\uff1a\u751f\u7269\u5438\u9644\u6027\u5948\u7c73\u7c92\u5b50\/\u5438\u6536\u7d2b\u5916\u5149\u7684\u5206\u5b50\u3002<\/figcaption><\/figure>\n

\u9664\u6b64\u4e4b\u5916\uff0c\u628a\u5438\u6536\u7d2b\u5916\u5149\u7684\u7269\u8cea\u95dc\u5728\u7c92\u5b50\u88e1\u9084\u6709\u4e00\u500b\u597d\u8655\uff1a\u4e00\u822c\u9632\u66ec\u4e73\u5857\u62b9\u5728\u76ae\u819a\u4e0a\u4e4b\u5f8c\uff0c\u9019\u4e9b\u7269\u8cea\u5c31\u6703\u6162\u6162\u9032\u5165\u8868\u76ae\u8ddf\u771f\u76ae\u5c64\uff0c\u4e5f\u5c31\u662f\u8aaa\u5438\u6536\u7d2b\u5916\u5149\u7684\u6709\u6a5f\u7269\u5df2\u7d93\u4e0d\u5728\u76ae\u819a\u8868\u9762\u4fdd\u8b77\u6211\u5011\u4e86\uff0c\u4f46\u56e0\u70ba\u9019\u9805\u7814\u7a76\u6240\u4f7f\u7528\u5177\u751f\u7269\u5438\u9644\u6027\u7684\u7c92\u5b50\u53ea\u6703\u505c\u7559\u5728\u89d2\u8cea\u5c64\uff0c\u4e5f\u5c31\u662f\u76ae\u819a\u7684\u6700\u5916\u5c64\uff0c\u56e0\u6b64\u4fdd\u8b77\u6548\u679c\u66f4\u597d\u3002\u6839\u64da\u5be6\u9a57\u986f\u793a\uff0c\u9019\u7a2e\u7d50\u69cb\u8ddf\u4e00\u822c\u9632\u66ec\u4e73\u76f8\u6bd4\uff0c\u53ea\u9700\u8981\u542b\u6709\u4e00\u822c\u9632\u66ec\u4e73\u6fc3\u5ea65%\u7684\u7d2b\u5916\u7dda\u5438\u6536\u5206\u5b50\u5c31\u53ef\u4ee5\u9054\u5230\u76f8\u540c\u6548\u679c\u3002<\/p>\n

\u9019\u7bc7\u7814\u7a76\u7684\u4f5c\u8005\u4e4b\u4e00\uff0c\u4f86\u81ea\u8036\u9b6f\u5927\u5b78\u91ab\u5b78\u9662\u76ae\u819a\u79d1\u7684Michael Girardi\u6559\u6388\u8868\u793a\uff1a\u300c\u4e00\u822c\u5e02\u552e\u7684\u9632\u66ec\u4e73\u90fd\u662f\u4fdd\u8b77\u76ae\u819a\u514d\u65bc\u53d7\u5230\u7d2b\u5916\u5149\u9020\u6210\u7684\u76f4\u63a5\u50b7\u5bb3\uff0c\u4f46\u537b\u7121\u6cd5\u9632\u7bc4\u9593\u63a5\u50b7\u5bb3\u3002\u300d\u300c\u53ea\u6709\u5c11\u6578\u7684\u7814\u7a76\u91dd\u5c0d\u6709\u6a5f\u7269\u5438\u6536\u7d2b\u5916\u5149\u5f8c\u7522\u751f\u6d3b\u6027\u6c27\u5316\u7269\u9020\u6210\u7684\u5371\u5bb3\u3002\u4f46\u5f88\u660e\u986f\uff0c\u9019\u662f\u975e\u5e38\u9700\u8981\u6ce8\u610f\u7684\u3002\u300d\u7cbe\u901a\u76ae\u819a\u764c\u7684Michael Girardi\u6559\u6388\u9084\u8aaa\uff1a\u300c\u4e8b\u5be6\u4e0a\u5728\u6211\u5011\u4f7f\u7528\u9632\u66ec\u4e73\u6642\uff0c\u9019\u4e9b\u9593\u63a5\u50b7\u5bb3\u9084\u66f4\u52a0\u56b4\u91cd\u3002\u300d<\/p>\n

\u539f\u59cb\u8ad6\u6587\uff1a<\/strong>Deng, Yang, Asiri Ediriwickrema, Fan Yang, Julia Lewis, Michael Girardi, and W. Mark Saltzman. \"A sunblock based on bioadhesive nanoparticles.\"\u00a0Nature materials<\/em>\u00a0(2015).<\/p>\n

\u53c3\u8003\u8cc7\u6599\uff1a<\/strong><\/p>\n

    \n
  1. A new sunblock that doesn't penetrate the skin<\/a><\/li>\n
  2. \u6d3b\u6027\u6c27\u7269\u7a2e<\/a><\/li>\n
  3. \u81ea\u7531\u57fa\u8207\u6d3b\u6027\u6c27\u5316\u7269 \u2500 \u4e0a<\/a><\/li>\n
  4. \u81ea\u7531\u57fa\u8207\u6d3b\u6027\u6c27\u5316\u7269 \u2500 \u4e0b<\/a><\/li>\n<\/ol>\n

    --<\/strong><\/span>
    \u4f5c\u8005\uff1a\u65b9\u7a0b\u6bc5 \u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b\uff0c\u5f9e\u4e8b\u79d1\u666e\u6587\u7ae0\u5beb\u4f5c\u3002<\/strong><\/span><\/p>\n

     <\/p>\n

    \"\u52a0\u5165\u597d\u53cb\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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