{"id":21753,"date":"2015-08-12T08:04:52","date_gmt":"2015-08-12T00:04:52","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=21753"},"modified":"2018-08-01T16:01:21","modified_gmt":"2018-08-01T08:01:21","slug":"%e3%80%90%e5%af%b5%e7%89%a9%e5%b0%88%e6%ac%84%e3%80%91%e8%b2%93%e5%92%aa%e7%82%ba%e4%bd%95%e7%89%b9%e5%88%a5%e6%8c%91%e5%98%b4%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=21753","title":{"rendered":"\u3010\u5bf5\u7269\u5c08\u6b04\u3011\u8c93\u54aa\u70ba\u4f55\u7279\u5225\u6311\u5634\uff1f"},"content":{"rendered":"<figure id=\"attachment_21754\" aria-describedby=\"caption-attachment-21754\" style=\"width: 450px\" class=\"wp-caption alignleft\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-21754\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/06\/CC0-Public-Domain.png\" alt=\"CC0 Public Domain\" width=\"450\" height=\"299\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/06\/CC0-Public-Domain.png 554w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/06\/CC0-Public-Domain-300x199.png 300w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><figcaption id=\"caption-attachment-21754\" class=\"wp-caption-text\">CC0 Public Domain<\/figcaption><\/figure>\n<p><strong>\u64b0\u6587\uff5c<\/strong>\u9ec3\u8c9e\u7965<\/p>\n<p>\u8c93\u54aa\u662f\u6709\u540d\u7684\u6311\u5634\uff0c\u6709\u8a31\u591a\u6771\u897f\u6839\u672c\u7121\u6cd5\u5f37\u8feb\u7260\u5011\u98df\u7528\uff0c\u6709\u4e9b\u6211\u5011\u559c\u611b\u7684\u98df\u7269\uff0c\u8c93\u4e00\u805e\u5230\u537b\u6703\u76ba\u7709\u982d\u3002\u79d1\u5b78\u5bb6\u767c\u73fe\uff0c\u539f\u4f86\u8c93\u54aa\u5c0d\u4e00\u4e9b\u82e6\u5473\u5206\u5b50\u7684\u611f\u77e5\uff0c\u53ef\u80fd\u548c\u4eba\u985e\u975e\u5e38\u4e0d\u540c\u3002<\/p>\n<p>\u80fd\u5617\u51fa\u82e6\u5473\uff0c\u6709\u53ef\u80fd\u662f\u70ba\u4e86\u907f\u514d\u690d\u7269\u88e1\u7684\u6709\u6bd2\u5316\u5408\u7269\u3002\u8c93\u79d1\u52d5\u7269\uff0c\u5f9e\u731b\u864e\u5230\u5bb6\u8c93\u90fd\u662f\u8089\u98df\u52d5\u7269\uff0c\u751a\u5c11\u98df\u7528\u690d\u7269\u3002\u53ef\u662f\u7260\u5011\u9084\u662f\u80fd\u5617\u51fa\u82e6\u5473\uff0c\u53ea\u4e0d\u904e\u548c\u4eba\u985e\u7684\u53cd\u61c9\u5f88\u4e0d\u76f8\u540c\u3002\u904e\u53bb\u7684\u7814\u7a76\u77ad\u89e3\u5230\u8c93\u54aa\u7121\u6cd5\u5617\u5230\u751c\u5473\uff0c\u53ef\u662f\u5c0d\u5bb6\u8c93\u7684\u5176\u4ed6\u5473\u89ba\u6240\u77e5\u751a\u5c11\u3002<\/p>\n<p>\u7f8e\u570bIntegral Molecular Inc.\u7684Joseph Rucker\u548cAFB International\u7684Nancy Rawson\u7b49\u4eba\u5229\u7528\u7d30\u80de\u5be6\u9a57\uff0c\u63a2\u8a0e\u4e86\u8c93\u7684\u82e6\u5473\u53d7\u5668\u5c0d\u82e6\u5473\u5206\u5b50\u7684\u53cd\u61c9\u3002\u548c\u4eba\u985e\u7684\u540c\u6e90\u53d7\u5668\u76f8\u6bd4\uff0c\u8c93\u7684\u82e6\u5473\u53d7\u5668Tas2r38\u5247\u5c0d\u82e6\u5473\u5206\u5b50\u82ef\u786b\u8132(Phenylthiocarbamide\uff0cPTC)\u7684\u654f\u611f\u5ea6\u5c11\u4e86\u5341\u500d\uff0c\u800c\u4e14\u5c0d\u53e6\u4e00\u500b\u82e6\u5473\u5206\u5b50\u4e19\u786b\u6c27\u5627\u5576(6-n-Propylthiouracil\uff0cPROP)\u6c92\u6709\u53cd\u61c9\u3002TAS2R38\u5728\u4eba\u985e\u7684\u4e00\u4e9b\u8b8a\u7570\uff0c\u6703\u8b93\u4e00\u4e9b\u4eba\u5c0d\u82e6\u5473\u7570\u5e38\u654f\u611f\uff0c\u4f7f\u5f97\u4ed6\u5011\u901a\u5e38\u5c0d\u6930\u82b1\u83dc\u548c\u7518\u85cd\u656c\u8b1d\u4e0d\u654f\u3002<!--more--><\/p>\n<p>\u53ef\u662f\u548c\u4eba\u985e\u7684\u53d7\u5668\u4e00\u6a23\uff0c\u8c93\u7684Tas2r43\u4e5f\u6703\u88ab\u8606\u8588\u7d20(Aloin)\u548c\u82ef\u7532\u5730\u90a3\u92a8(denatonium)\u6d3b\u5316\uff0c\u5f8c\u8005\u5e38\u7528\u4f86\u963b\u6b62\u5152\u7ae5\u6216\u5bf5\u7269\u541e\u98df\u4e00\u4e9b\u5316\u5b78\u85e5\u5291\u5982\u6297\u51cd\u5291\u7b49\uff0c\u53ea\u4e0d\u904e\u5b83\u5c0d\u524d\u8005\u8f03\u4e0d\u654f\u611f\u4f46\u5c0d\u5f8c\u8005\u66f4\u654f\u611f\uff1b\u53e6\u5916\uff0cTas2r43\u5c0d\u6703\u7559\u4e0b\u82e6\u5473\u9918\u97fb\u7684\u4eba\u5de5\u751c\u5473\u5291\u7cd6\u7cbe(saccharin)\u4e0d\u654f\u611f\u3002<\/p>\n<p>\u9019\u500b\u7814\u7a76\u5c07\u6709\u52a9\u5bf5\u7269\u98df\u54c1\u696d\u8005\u6539\u9032\u4ed6\u5011\u7684\u8c93\u5473\u98df\u54c1\uff0c\u4e26\u4e14\u6709\u53ef\u80fd\u7528\u4f86\u8a2d\u6cd5\u8b93\u8c93\u54aa\u5c0d\u4e00\u4e9b\u85e5\u7269\u4e0d\u518d\u96e3\u4ee5\u63a5\u53d7\u3002<\/p>\n<p><strong>\u539f\u5b78\u8853\u8ad6\u6587\uff1a<\/strong><br \/>\nSandau MM, Goodman JR, Thomas A, Rucker JB, Rawson NE. A functional comparison of the domestic cat bitter receptors Tas2r38 and Tas2r43 with their human orthologs. BMC Neurosci. 2015 Jun 3;16:33. doi: 10.1186\/s12868-015-0170-6.<\/p>\n<p><strong>\u53c3\u8003\u8cc7\u6599\uff1a<\/strong><br \/>\n1. Brian Stallard. <a href=\"http:\/\/www.natureworldnews.com\/articles\/14987\/20150602\/why-cats-such-picky-eaters-better-bitter-felines.htm\" target=\"_blank\" rel=\"noopener noreferrer\">Why Cats Are Such Picky Eaters: a Better Bitter for Felines. <\/a>Nature World News. Jun 02, 2015.<br \/>\n2. Aamna Mohdin. <a href=\"http:\/\/www.iflscience.com\/plants-and-animals\/here-s-why-your-cat-such-picky-eater\" target=\"_blank\" rel=\"noopener noreferrer\">Here\u2019s Why Your Cat Is Such A Picky Eater.<\/a> IFLScience. June 3, 2015.<br \/>\n3. Emily DeMarco.<a href=\"http:\/\/news.sciencemag.org\/biology\/2015\/06\/my-cat-bitter-or-does-he-just-taste-way\" target=\"_blank\" rel=\"noopener noreferrer\"> Is my cat bitter, or does he just taste that way? SCIENCESHOT. <\/a>Science| DOI: 10.1126\/science.aac6777.2 June 2015.<\/p>\n<p><span style=\"color: #333399;\"><strong>--<\/strong><\/span><br style=\"color: #000000;\" \/><span style=\"color: #333399;\"><strong>\u4f5c\u8005\uff1a\u9ec3\u8c9e\u7965 \u73fe\u65bc\u53f0\u7063\u4e2d\u592e\u7814\u7a76\u9662\u751f\u7269\u591a\u6a23\u6027\u7814\u7a76\u4e2d\u5fc3\u64d4\u4efb\u535a\u58eb\u5f8c\u7814\u7a76\u54e1\uff0c\u5f9e\u4e8b\u9ce5\u985e\u7684\u6f14\u5316\u907a\u50b3\u5b78\u3001\u57fa\u56e0\u9ad4\u5b78\u53ca\u6f14\u5316\u767c\u80b2 \u751f\u7269\u5b78\u7814\u7a76\u3002\u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b\uff0c\u5f9e\u4e8b\u79d1\u666e\u6587\u7ae0\u5beb\u4f5c\u3002<\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u64b0\u6587\uff5c\u9ec3\u8c9e\u7965 \u8c93\u54aa\u662f\u6709\u540d\u7684\u6311\u5634\uff0c\u6709\u8a31\u591a\u6771<\/p>\n","protected":false},"author":20,"featured_media":21754,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,26],"tags":[382,1765,1968,164,1590],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/06\/CC0-Public-Domain.png","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/21753"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=21753"}],"version-history":[{"count":5,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/21753\/revisions"}],"predecessor-version":[{"id":32313,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/21753\/revisions\/32313"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/21754"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=21753"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=21753"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=21753"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}