{"id":21380,"date":"2015-06-01T00:47:35","date_gmt":"2015-05-31T16:47:35","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=21380"},"modified":"2018-08-01T15:52:27","modified_gmt":"2018-08-01T07:52:27","slug":"%e3%80%90%e9%86%ab%e5%ad%b8%e7%a0%94%e7%a9%b6%e3%80%91%e8%80%81%e8%97%a5%e6%96%b0%e7%94%a8%ef%bc%8d%e5%88%a9%e5%b0%bf%e5%8a%91%e6%b2%bb%e5%94%90%e6%b0%8f%e7%97%87%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=21380","title":{"rendered":"\u3010\u91ab\u5b78\u7814\u7a76\u3011\u8001\u85e5\u65b0\u7528\uff0d\u5229\u5c3f\u5291\u6cbb\u5510\u6c0f\u75c7\uff1f"},"content":{"rendered":"

\u25a0\u5510\u6c0f\u75c7\u6216\u8a31\u662f\u6700\u666e\u904d\u7684\u4e00\u7a2e\u67d3\u8272\u9ad4\u7570\u5e38\u75be\u75c5\uff0c\u6839\u64da2010\u5728\u00a0Birth Defects Research Part A\u00a0<\/em>\u7684\u7d71\u8a08\u986f\u793a\uff0c\u5510\u6c0f\u75c7\u5728\u4eba\u985e\u7fa4\u9ad4\u7684\u76db\u884c\u7387\u5927\u7d04\u662f\u5343\u5206\u4e4b\u4e00\uff0c\u5927\u7d04\u6bcf\u4e03\u767e\u500b\u9806\u7522\u5b30\u5152\u4e2d\uff0c\u5c31\u6709\u4e00\u500b\u5510\u6c0f\u75c7\u3002\u5510\u6c0f\u75c7\u60a3\u8005\u7684\u559c\u61a8\u7e3d\u662f\u8b93\u4eba\u5fc3\u75bc\uff0c\u6709\u6c92\u6709\u53ef\u80fd\u6709\u4e00\u7a2e\u9b54\u6cd5\uff0c\u53ef\u4ee5\u8b93\u4ed6\u5011\u81c9\u4e0a\u6b61\u559c\u53c8\u6eab\u6696\u7684\u7b11\u5bb9\u4f9d\u820a\u5e38\u99d0\uff0c\u537b\u4e0d\u518d\u662f\u61a8\u5152\u5462\uff1f<\/strong><\/span><\/p>\n

\"credit<\/a>
credit to pablo pineda(FB)<\/figcaption><\/figure>\n

\u64b0\u6587\uff5c<\/strong>\u99f1\u5b9b\u7433<\/p>\n

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\u53c3\u8003\u8cc7\u6599\uff1a<\/strong>
\n1. Costa AC. \u00a0Intracellular chloride accumulation: a possible mechanism for cognitive deficits in Down syndrome. Nat Med<\/em>. 2015 Apr 7;21(4):312-3. doi: 10.1038\/nm.3836.
\n2. Deidda G. et al. Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome. Nat Med.<\/em> 2015 Apr;21(4):318-26. doi: 10.1038\/nm.3827. Epub 2015 Mar 16.
\n3. Parker SE. et al. Updated National Birth Prevalence estimates for selected birth defects in the United States, 2004-2006. Birth Defects Res A Clin Mol Teratol.<\/em> 2010 Dec;88(12):1008-16. doi: 10.1002\/bdra.20735. Epub 2010 Sep 28.<\/p>\n

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