{"id":21256,"date":"2015-06-10T00:07:20","date_gmt":"2015-06-09T16:07:20","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=21256"},"modified":"2018-08-01T15:48:30","modified_gmt":"2018-08-01T07:48:30","slug":"%e3%80%90%e7%b4%b0%e8%8f%8c%e7%a0%94%e7%a9%b6%e3%80%91%e7%8b%a9%e7%8d%b5%e6%8e%a1%e9%9b%86%e6%97%8f%e7%be%a4%e7%9a%84%e8%85%b8%e9%81%93%e8%8f%8c%e7%9c%9f%e7%9a%84%e8%b7%9f%e6%88%91%e5%80%91%e4%b8%8d","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=21256","title":{"rendered":"\u3010\u7d30\u83cc\u7814\u7a76\u3011\u72e9\u7375\u63a1\u96c6\u65cf\u7fa4\u7684\u8178\u9053\u83cc\u771f\u7684\u8ddf\u6211\u5011\u4e0d\u4e00\u6a23\u55ce\uff1f"},"content":{"rendered":"<p><span style=\"color: #333399;\"><strong>\u25a0<\/strong><strong>\u904e\u53bb\u6709\u7814\u7a76\u8a8d\u70ba\uff0c\u56de\u5230\u72e9\u7375<\/strong><strong>\/<\/strong><strong>\u63a1\u96c6\u65cf\u7fa4\u7684\u98f2\u98df\u65b9\u5f0f\uff08<\/strong><strong>paleo diet<\/strong><strong>\uff0c\u591a\u6a23\u3001\u5c11\u91cf\u7684\u651d\u98df\u65b9\u5f0f\uff09\u5c0d\u6211\u5011\u662f\u6709\u597d\u8655\u7684\uff1b\u771f\u7684\u6709\u597d\u8655\u55ce\uff1f<\/strong><\/span><\/p>\n<figure id=\"attachment_21257\" aria-describedby=\"caption-attachment-21257\" style=\"width: 380px\" class=\"wp-caption alignleft\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-21257\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/04\/Mayoruna.jpg\" alt=\"Mats\u00e9s \u65cf\u4eba\u3002\u5716\u7247\u4f86\u6e90\uff1awiki\" width=\"380\" height=\"253\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/04\/Mayoruna.jpg 380w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/04\/Mayoruna-300x199.jpg 300w\" sizes=\"(max-width: 380px) 100vw, 380px\" \/><figcaption id=\"caption-attachment-21257\" class=\"wp-caption-text\">Mats\u00e9s \u65cf\u4eba\u3002\u5716\u7247\u4f86\u6e90\uff1awiki<\/figcaption><\/figure>\n<p><strong>\u64b0\u6587\uff5c<\/strong>\u8449\u7da0\u8212<\/p>\n<p>\u6700\u8fd1\u666e\u6717\u514b\u7814\u7a76\u6240(Mas Planck Institute)\u5c0d\u5c45\u4f4f\u5728\u79d8\u9b6f\u3001\u5df4\u897f\u4e00\u5e36\u7684Mats\u00e9s \u65cf\u7684\u8178\u9053\u83cc\u9032\u884c\u7814\u7a76\u767c\u73fe\uff0c\u6700\u5927\u7684\u4e0d\u540c\u5728\u65bc\u4ed6\u5011\u7684\u8178\u5b50\u88e1\u9762\u6709\u87ba\u65cb\u9ad4(<em>Treponema<\/em>)\uff01<\/p>\n<p>\u7531\u65bcMats\u00e9s \u65cf\u53ef\u8aaa\u662f\u4e16\u754c\u4e0a\u78a9\u679c\u50c5\u5b58\u7684\u5e7e\u500b\u72e9\u7375\/\u63a1\u96c6\u65cf\u7fa4\uff0c\u8981\u5982\u4f55\u8ddf\u4ed6\u5011\u9032\u884c\u4e92\u52d5\uff0c\u5df4\u897f\u653f\u5e9c\u6709\u5f88\u591a\u898f\u5b9a\u3002\u4f46\u662f\u8981\u7814\u7a76\u4eba\uff08\u4e0d\u7ba1\u662f\u4eba\u7684\u4ec0\u9ebc\uff09\uff0c\u4e00\u5b9a\u8981\u5c0d\u65b9\u300c\u77e5\u60c5\u540c\u610f\u300d(informed consent)\u624d\u884c\u3002\u96d6\u8aaa\u8178\u9053\u83cc\u7684\u7814\u7a76\u53ea\u9700\u8981\u6536\u96c6\u5927\u865f\uff0c\u518d\u7531\u5176\u4e2d\u5206\u6790\u7d30\u83cc\u7684\u7d44\u6210\u5c31\u597d\uff1b\u4f46\u300c\u77e5\u60c5\u540c\u610f\u300d\u9019\u500b\u6b65\u9a5f\u9084\u662f\u4e0d\u53ef\u5c11\u3002\u56e0\u6b64\uff0c\u70ba\u4e86\u53d6\u5f97\u5c0d\u65b9\u7684\u540c\u610f\uff0c\u5e7e\u4f4d\u4eba\u985e\u5b78\u5bb6\u7d66\u4e86Mats\u00e9s \u65cf\u4eba\u4e00\u5802\u7c21\u55ae\u7684\u5fae\u751f\u7269\u5b78\u8ab2\u7a0b\uff0c\u4e26\u8b93\u4ed6\u5011\u770b\u4e86\u986f\u5fae\u93e1\u4e0b\u7684\u7d30\u83cc...\u3002\u5f88\u986f\u7136\u5730\uff0c\u8ab2\u7a0b\u5f88\u6210\u529f\uff0c\u56e0\u70ba\u5176\u4e2d\u4e00\u4f4dMats\u00e9s \u65cf\u4eba\u554f\u7814\u7a76\u5718\u968a\uff0c\u9019\u4e9b\u8178\u5b50\u88e1\u7684\u5fae\u751f\u7269\u662f\u5426\u5c31\u662f\u8b93\u4ed6\u5c0f\u6642\u5019\u53ef\u4ee5\u559d\u5976\uff0c\u9577\u5927\u5f8c\u537b\u4e0d\u80fd\u518d\u559d\u7684\u300c\u5147\u624b\u300d\u5462\uff08\u55ef...\u53ef\u4ee5\u9019\u9ebc\u8aaa\u5566\uff01\uff09\uff1f<!--more--><\/p>\n<p>\u7814\u7a76\u5718\u968a\u6bd4\u8f03\u4e86 25\u540dMats\u00e9s \u65cf\u4eba\uff08\u6355\u7375\u7334\u5b50\u3001\u6a39\u61f6\u3001\u6316\u6398\u91ce\u751f\u584a\u8396\u7dad\u751f\uff09\u3001 31\u540d\u5c45\u4f4f\u5728 Tunapuco\uff08\u5b89\u5730\u65af\u9ad8\u539f\uff09\u7684\u99ac\u9234\u85af\u8fb2\u592b\uff08\u7a2e\u690d\u99ac\u9234\u85af\u3001\u5403\u5929\u7afa\u9f20\u3001\u8c6c\u3001\u7f8a\u3001\u4e73\u916a\uff09\uff0c\u548c 23\u540d\u5c45\u4f4f\u5728 Norman\u7684\u5b78\u6821\u6559\u8077\u54e1\uff08\u5403\u52a0\u5de5\u98df\u54c1\uff1a\u7f50\u982d\u6c34\u679c\u3001\u852c\u83dc\u3001\u8089\uff09\u7684\u8178\u9053\u83cc\u3002<\/p>\n<figure id=\"attachment_21258\" aria-describedby=\"caption-attachment-21258\" style=\"width: 500px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-21258\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/04\/ncomms7505-f2.jpg\" alt=\"\u4e09\u500b\u65cf\u7fa4\u7684\u8178\u9053\u83cc\u5206\u6790\u7d50\u679c\u3002\u5716\u7247\u4f86\u6e90\uff1aNature Communications\" width=\"500\" height=\"502\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/04\/ncomms7505-f2.jpg 946w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/04\/ncomms7505-f2-150x150.jpg 150w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/04\/ncomms7505-f2-298x300.jpg 298w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/04\/ncomms7505-f2-800x803.jpg 800w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><figcaption id=\"caption-attachment-21258\" class=\"wp-caption-text\">\u4e09\u500b\u65cf\u7fa4\u7684\u8178\u9053\u83cc\u5206\u6790\u7d50\u679c\u3002\u5716\u7247\u4f86\u6e90\uff1aNature Communications<\/figcaption><\/figure>\n<p>\u7d50\u679c\u767c\u73fe\uff0cMats\u00e9s \u65cf\u4eba\u548cTunapuco\u8fb2\u592b\u7684\u8178\u9053\u83cc\u4e0d\u4f46\u6bd4\u4f4f\u5728Norman\u7684\u5b78\u6821\u6559\u8077\u54e1\u8c50\u5bcc\u7684\u591a\uff0c\u4e14\u5177\u7279\u6709\u7684\u87ba\u65cb\u9ad4(<em>Treponema<\/em>)\uff0c\u4e0d\u904e\u4e0d\u662f\u6703\u5c0e\u81f4\u6885\u6bd2\u7684\u87ba\u65cb\u9ad4\u5594\uff01\u63a5\u8457\u7814\u7a76\u5718\u968a\u5c07Mats\u00e9s \u65cf\u4eba\u8178\u9053\u83cc\u4e2d\u7684\u87ba\u65cb\u9ad4\u9032\u4e00\u6b65\u5206\u6790\uff0c\u7d50\u679c\u986f\u793a\uff1a\u9019\u4e9b\u87ba\u65cb\u9ad4\u8207\u8c6c\u8178\u9053\u83cc\u4e2d\u8ca0\u8cac\u5354\u52a9\u78b3\u6c34\u5316\u5408\u7269\u4ee3\u8b1d\u7684 <em>Treponema succinifaciens<\/em>\u975e\u5e38\u76f8\u4f3c\uff0816S \u6838\u7cd6\u9ad4RNA\u5e8f\u5217\u5206\u6790\u5177 90~99% \u76f8\u4f3c\u5ea6\uff09\u3002<\/p>\n<p>\u7531\u65bc\u904e\u53bb\u7814\u7a76\u4e5f\u66fe\u5728\u5766\u6851\u5c3c\u4e9e Hadza \u65cf\u4eba\u548c\u5176\u4ed6\u9748\u9577\u985e\u8178\u9053\u4e2d\u767c\u73fe\u87ba\u65cb\u9ad4\u3002\u9019\u500b\u767c\u73fe\u518d\u6b21\u63d0\u793a\u4e86\u87ba\u65cb\u9ad4\u672c\u5c31\u5b58\u5728\u65bc\u6211\u5011\u8178\u9053\u4e2d\uff0c\u53ea\u662f\u5728\u4eba\u985e\u5b78\u6703\u4e86\u7a2e\u7530\u5f8c\uff0c\u4e0d\u77e5\u4f55\u6642\uff08\u6216\u8a31\u662f\u958b\u59cb\u5927\u91cf\u651d\u53d6\u52a0\u5de5\u98df\u54c1\u7684\u6642\u5019\uff1f\uff09\u87ba\u65cb\u9ad4\u5c31\u8ddf\u6211\u5011\u5206\u9053\u63da\u9463\u4e86\u3002\u7531\u65bc\u87ba\u65cb\u9ad4\u4e5f\u51fa\u73fe\u5728Tunapuco\u99ac\u9234\u85af\u8fb2\u592b\u9ad4\u5167\uff0c\u800c\u9019\u4e9b\u8fb2\u4eba\u5011\u9084\u7dad\u6301\u8457\u5403\u83dc\u6bd4\u5403\u8089\u591a\u3001\u5c11\u52a0\u5de5\u98df\u54c1\u7684\u98f2\u98df\u578b\u614b\u3002\u56e0\u6b64\u7814\u7a76\u5718\u968a\u8a8d\u70ba\uff0c\u90fd\u5e02\u5316\u3001\u5de5\u696d\u5316\u7684\u65cf\u7fa4\u56e0\u70ba\u591a\u98df\u7528\u52a0\u5de5\u98df\u54c1\u3001\u5c11\u5403\u852c\u679c\uff0c\u4e0d\u4f46\u4f7f\u5f97\u6211\u5011\u8178\u9053\u7684\u83cc\u76f8\u4e0d\u518d\u591a\u5143\uff0c\u4ea6\u8b93\u87ba\u65cb\u9ad4\u6c38\u9060\u96e2\u958b\u4e86\u6211\u5011\u3002<\/p>\n<p>\u4f46\u662f\uff0c\u662f\u5426\u5931\u53bb\u4e86\u87ba\u65cb\u9ad4\u548c\u591a\u5143\u83cc\u76f8\uff0c\u5c31\u662f\u9020\u6210\u73fe\u4ee3\u4eba\u7f79\u60a3\u8ddf\u8178\u9053\u76f8\u95dc\u81ea\u9ad4\u514d\u75ab\u75be\u75c5\u7684\u539f\u56e0\u5462\uff08\u5982\u514b\u9686\u6c0f\u75c7Crohn\u2019s disease\uff09\uff1f\u9019\u90e8\u4efd\u5247\u5c1a\u5f85\u79d1\u5b78\u9a57\u8b49\u3002\u6216\u8a31\u672a\u4f86\u53ef\u4ee5\u5c07\u9019\u4e9b\u87ba\u65cb\u9ad4\u5217\u5165\u8178\u9053\u75be\u75c5\u7684\u5fae\u751f\u7269\u7642\u6cd5\u4e2d\uff0c\u4e0d\u904e\u7b46\u8005\u60f3\uff0c\u5373\u4f7f\u6211\u5011\u670d\u7528\u4e86\u9019\u4e9b\u87ba\u65cb\u9ad4\uff0c\u4f46\u98f2\u98df\u7fd2\u6163\u672a\u6539\u8b8a\uff0c\u9019\u4e9b\u87ba\u65cb\u9ad4\u5927\u6982\u5f88\u5feb\u53c8\u6703\u8ddf\u6211\u5011\u8aaa\u63b0\u63b0\uff0c\u7136\u5f8c\u6211\u5011\u53c8\u8981\u809a\u5b50\u75db\u3001\u62c9\u809a\u5b50\u4e86\u3002\u5509\uff01<\/p>\n<p><strong>\u53c3\u8003\u6587\u737b\uff1a<\/strong><br \/>\n1. Ann Gibbons. 2015\/3\/25.\u00a0<a href=\"http:\/\/news.sciencemag.org\/biology\/2015\/03\/ancient-bacteria-found-hunter-gatherer-guts\" target=\"_blank\" rel=\"noopener noreferrer\">Ancient bacteria found in hunter-gatherer guts<\/a>. Science Now.<br \/>\n2. A.J. Obregon-Tito et. al.,\u00a0<a href=\"http:\/\/www.nature.com\/ncomms\/2015\/150325\/ncomms7505\/full\/ncomms7505.html\" target=\"_blank\" rel=\"noopener noreferrer\">Subsistence strategies in traditional societies distinguish gut microbiomes<\/a>. Nature Communications. doi: 10.1038\/ncomms7505<\/p>\n<p><span style=\"color: #333399;\"><strong>--<\/strong><\/span><br style=\"color: #000000;\" \/><span style=\"color: #333399;\"><strong>\u4f5c\u8005\uff1a\u8449\u7da0\u8212\u3000\u6148\u6fdf\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb\u52a9\u7406\u6559\u6388\uff0c\u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b\uff0c\u5f9e\u4e8b\u79d1\u666e\u6587\u7ae0\u5beb\u4f5c\u3002<\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0\u904e\u53bb\u6709\u7814\u7a76\u8a8d\u70ba\uff0c\u56de\u5230\u72e9\u7375\/\u63a1\u96c6\u65cf\u7fa4\u7684\u98f2<\/p>\n","protected":false},"author":20,"featured_media":21257,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,1025],"tags":[297,1793,1794,1792,1543,1795],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/04\/Mayoruna.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/21256"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=21256"}],"version-history":[{"count":4,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/21256\/revisions"}],"predecessor-version":[{"id":32263,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/21256\/revisions\/32263"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/21257"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=21256"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=21256"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=21256"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}