{"id":20984,"date":"2015-04-02T00:15:28","date_gmt":"2015-04-01T16:15:28","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=20984"},"modified":"2018-08-01T15:39:20","modified_gmt":"2018-08-01T07:39:20","slug":"%e7%b5%90%e5%90%88%e7%b4%b0%e8%8f%8c%e8%88%87%e6%99%b6%e7%89%87%e7%9a%84%e4%bb%bf%e7%94%9f%e8%91%89%ef%bc%88bionic-leaf%ef%bc%89","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=20984","title":{"rendered":"\u3010\u80fd\u6e90\u5951\u6a5f\u3011\u7d50\u5408\u7d30\u83cc\u8207\u6676\u7247\u7684\u4eff\u751f\u8449"},"content":{"rendered":"<p><span style=\"color: #333399;\"><strong>\u25a0\u54c8\u4f5b\u7814\u7a76\u5718\u968a\u7d50\u5408\u592a\u967d\u80fd\u96fb\u6c60(\u6216\u7a31\u592a\u967d\u80fd\u6676\u7247)\u8207\u4e00\u96bb\u540d\u70ba<em>Ralstonia eutropha<\/em>\u7684\u7d30\u83cc\u53bb\u6a21\u64ec\u8449\u7247\u884c\u5149\u5408\u4f5c\u7528\uff0c\u53ef\u4ee5\u5c07\u5149\u80fd\u4ee5\u5316\u5b78\u80fd\u7684\u65b9\u5f0f\u5132\u5b58\u8d77\u4f86\uff0c\u672a\u4f86\u767c\u5c55\u76f8\u7576\u4ee4\u4eba\u671f\u5f85\uff01<\/strong><\/span><\/p>\n<figure id=\"attachment_20985\" aria-describedby=\"caption-attachment-20985\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/03\/F1.large_.jpg\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-20985\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/03\/F1.large_-1024x267.jpg\" alt=\"F1.large\" width=\"600\" height=\"157\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/03\/F1.large_-1024x267.jpg 1024w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/03\/F1.large_-300x78.jpg 300w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/03\/F1.large_-800x209.jpg 800w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/03\/F1.large_-600x157.jpg 600w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/03\/F1.large_.jpg 1280w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/a><figcaption id=\"caption-attachment-20985\" class=\"wp-caption-text\">\u7d50\u5408\u7d30\u83cc\u8207\u6676\u7247\u7684\u6db2\u614b\u80fd\u6e90\u7522\u751f\u7cfb\u7d71\u3002\u5716\u7247\u4f86\u6e90\uff1aScience, Li et. al., 2012<\/figcaption><\/figure>\n<p><strong>\u64b0\u6587\uff5c<\/strong>\u8449\u7da0\u8212<\/p>\n<p>\u66ff\u4ee3\u80fd\u6e90\u7684\u767c\u5c55\uff0c\u9664\u4e86\u751f\u8cea\u9152\u7cbe\u3001\u751f\u8cea\u67f4\u6cb9\u5916\uff0c\u5176\u5be6\u4e5f\u6709\u8a31\u591a\u7814\u7a76\u5718\u968a\u5728\u7814\u767c\u5982\u4f55\u5c07\u592a\u967d\u80fd\u8f49\u70ba\u53ef\u5132\u5b58\u7684\u80fd\u6e90\u3002\u7562\u7adf\uff0c\u592a\u967d\u80fd\u4e0d\u9700\u8981\u5982\u751f\u8cea\u80fd\u6e90\u80cc\u8ca0\u8207\u4eba\u722d\u98df\u6216\u780d\u4f10\u68ee\u6797\u7684\u7f6a\u540d\uff0c\u53ea\u8981\u5929\u7a7a\u6c92\u6709\u88ab\u96f2\u7c60\u7f69\uff0c\u5b83\u5c31\u662f\u53d6\u4e4b\u4e0d\u76e1\u7528\u4e4b\u4e0d\u7aed\u3002<\/p>\n<p>\u904e\u53bb\uff0c\u54c8\u4f5bNocera\u8001\u5e2b\u7684\u7814\u7a76\u5718\u968a\uff0c\u66fe\u7d93\u767c\u8868\u904e<a href=\"http:\/\/misc999.blogspot.tw\/2011\/09\/blog-post_30.html\">\u4ee5\u77fd(Si)\u70ba\u539f\u6599\u7684\u534a\u5c0e\u9ad4\u96fb\u6c60<\/a>\uff0c\u5b83\u53ef\u4ee5\u5728\u63a5\u53d7\u5149\u80fd\u5f8c\uff0c\u5229\u7528\u5149\u80fd\u8f49\u5316\u7684\u96fb\u80fd\u5c07\u6c34\u5206\u89e3\u70ba\u6c2b\u6c23(H2)\u8207\u6c27\u6c23(O2)\u3002\u96d6\u7136\u6c2b\u6c23\u4e5f\u53ef\u4ee5\u7528\u65bc\u71c3\u6599\uff0c\u4f46\u7531\u65bc\u6c2b\u6c23\u975e\u5e38\u5bb9\u6613\u81ea\u71c3\uff08\u4f54\u5927\u6c234%\u4ee5\u4e0a\u5373\u6709\u81ea\u71c3\u7684\u98a8\u96aa\uff09\u3001\u904b\u8f38\u8f03\u6db2\u614b\u80fd\u6e90\uff08\u6c7d\u6cb9\u3001\u67f4\u6cb9\u3001\u9152\u7cbe\uff09\u4e0d\u4fbf\uff0c\u52a0\u4e0a\u76ee\u524d\u7684\u5167\u71c3\u6a5f\uff08\u5f15\u64ce\uff09\u90fd\u9084\u662f\u4f7f\u7528\u6db2\u614b\u80fd\u6e90\u770b\u4f86\uff0c\u96d6\u7136\u6c2b\u6c23\u771f\u7684\u5f88\u74b0\u4fdd\uff08\u71c3\u71d2\u5b8c\u5c31\u5269\u4e0b\u6c34\uff09\uff0c\u4f46\u537b\u4e0d\u5927\u9069\u5408\u3002<!--more--><\/p>\n<p>\u65bc\u662f\u7814\u7a76\u5718\u968a\u958b\u59cb\u5c0b\u627e\u80fd\u628a\u6c2b\u6c23\u8f49\u63db\u6210\u70ba\u6db2\u614b\u80fd\u6e90\u7684\u65b9\u5f0f\u3002\u9019\u6b21\uff0c\u4ed6\u5011\u7d50\u5408\u4e86<a href=\"http:\/\/www.sciencemag.org\/content\/335\/6076\/1596.full?sid=95b82286-777c-45d7-be00-86558b20706e\">\u52a0\u5927\u6d1b\u6749\u78ef\u5206\u6821\u7684\u7814\u7a76\u5718\u968a<\/a>\u3002\u52a0\u5927\u5718\u968a\u5c07<em>Ralstonia eutropha<\/em>\u9019\u96bb\u83cc\u505a\u4e86\u4e00\u4e9b\u4fee\u6539\uff0c\u4f7f\u5b83\u5728\u990a\u5206\u4e0d\u8db3(nutrient-limited)\u7684\u72c0\u6cc1\u4e0b\u5c07\u4e59\u91af\u8f14\u9176A(acetyl-CoA)\u7528\u4f86\u7522\u751f\u7570\u4e19\u9187(isopropanol)\u3002\u539f\u672c<em>Ralstonia eutropha<\/em>\u6703\u5c07\u4e59\u91af\u8f14\u9176A\u5408\u6210PHB(polyhydroxybutyrate)\u5132\u5b58\u8d77\u4f86\uff0c\u4f46\u52a0\u5927\u7684\u7814\u7a76\u5718\u968a\u7528\u751f\u7269\u5de5\u7a0b\u7684\u65b9\u6cd5\u628a\u4e2d\u9593\u7684\u5169\u500b\u9175\u7d20\u53bb\u6389\uff0c\u7136\u5f8c\u690d\u5165\u5e36\u6709\u53e6\u5916\u56db\u500b\u57fa\u56e0\u7684\u8cea\u9ad4\uff0c\u4f7f\u7d30\u83cc\u4e0d\u518d\u80fd\u5920\u5408\u6210PHG\uff0c\u537b\u6709\u4e86\u5408\u6210\u7570\u4e19\u9187\u7684\u80fd\u529b\u3002\u65bc\u662f\uff0c\u7576\u9019\u96bb\u83cc\u5728\u7f3a\u4e4f\u6c2e\u6e90\u7684\u6642\u5019\uff0c\u53ea\u8981\u63d0\u4f9b\u7d66\u5b83\u6c2b\u6c23\u8207\u4e8c\u6c27\u5316\u78b3\uff0c\u5b83\u4fbf\u958b\u59cb\u7522\u751f\u7570\u4e19\u9187\u4e86\u3002\u96d6\u7136\u4e8c\u6c27\u5316\u78b3\u8981\u984d\u5916\u6253\u9032\u53bb\uff0c\u4f46\u4ee5\u73fe\u5728\u5730\u7403\u7684\u72c0\u6cc1\u4f86\u8aaa\uff0c\u4e8c\u6c27\u5316\u78b3\u591a\u5f97\u5f88\uff0c\u4e0d\u662f\u6b63\u597d\u53ef\u4ee5\u7528\u6389\u55ce\uff1f<\/p>\n<p>\u4f46\u662f\u5149\u53ea\u662f\u9019\u6a23\u9084\u4e0d\u884c\uff0c\u9019\u500b\u7cfb\u7d71\u9084\u6709\u4e00\u4e9b\u9700\u8981\u8abf\u6574\u7684\u5730\u65b9\u3002\u7531\u65bc\u4f7f\u7528\u96fb\u6975\u4f86\u5206\u89e3\u6c34\uff0c\u9664\u4e86\u6c2b\u6c23\u5df2\u5916\u4e5f\u6703\u7522\u751f\u6c27\u6c23\uff0c\u800c\u5728\u901a\u96fb\u7684\u72c0\u6cc1\u4e0b\uff0c\u4e0d\u514d\u6703\u7522\u751f\u4e00\u4e9b\u81ea\u7531\u57fa\u59a8\u7919\u7d30\u83cc\u751f\u9577\uff1b\u53e6\u5916\u662f\uff0c\u96fb\u6975\u82e5\u4f7f\u7528\u8cb4\u91d1\u5c6c\u767d\u91d1\u6216\u92a6(indium)\uff0c\u4e0d\u50c5\u9019\u4e9b\u91d1\u5c6c\u50f9\u683c\u6602\u8cb4\u3001\u4e0d\u6613\u53d6\u5f97\uff0c\u9019\u4e9b\u91d1\u5c6c\u5728\u81ea\u7136\u72c0\u6cc1\u4e0b\uff08\u5225\u5fd8\u8a18\uff0c\u9019\u500b\u7cfb\u7d71\u4f7f\u7528\u4e86\u7d30\u83cc\uff0c\u6240\u4ee5\u6240\u6709\u7684\u64cd\u4f5c\u8981\u76e1\u91cf\u7b26\u5408\u81ea\u7136\u72c0\u6cc1\uff09\u5c0d\u6c34\u7684\u96fb\u89e3\u529b\u4e5f\u4e0d\u9ad8\uff08\u9664\u975e\u63d0\u9ad8\u96fb\u58d3\uff0c\u4f46\u5982\u6b64\u4e00\u4f86\u53c8\u6703\u7522\u751f\u66f4\u591a\u81ea\u7531\u57fa\uff09\u3002<\/p>\n<p>\u7814\u7a76\u5718\u968a\u9996\u5148\u4f7f\u7528\u4e86\u78f7\u9178\u9237(CoPi)\u8207\u93b3\u9333\u92c5\/\u4e0d\u93fd\u92fc\u7684\u96fb\u6975\uff0c\u89e3\u6c7a\u4e86\u8cb4\u91d1\u5c6c\u8207\u96fb\u89e3\u529b\u4e0d\u8db3\u7684\u554f\u984c\uff1b\u4f46\u662f\u81ea\u7531\u57fa\u4ecd\u4e0d\u514d\u7522\u751f\uff0c\u65bc\u662f\u7814\u7a76\u5718\u968a\u5617\u8a66\u52a0\u5165\u4f86\u81ea\u725b\u809d\u7684\u904e\u6c27\u5316\u6c2b\u9176(catalase)\u3002\u5728\u904e\u6c27\u5316\u6c2b\u9176\u9806\u5229\u8655\u7406\u6389\u4e86\u81ea\u7531\u57fa\u7684\u554f\u984c\u5f8c\uff0c\u6574\u500b\u7cfb\u7d71\u7684\u7522\u80fd\u4f86\u5230\u6bcf\u516c\u5347\u57f9\u990a\u6db2\u7522\u51fa216\u6beb\u514b\u7684\u7570\u4e19\u9187\uff0c\u82e5\u63db\u7b97\u70ba\u592a\u967d\u80fd-\u751f\u8cea\u80fd\u8f49\u63db\u5247\u4f86\u52303.2%\uff0c\u70ba\u76ee\u524d\u6240\u6709\u5730\u7403\u4e0a\u7684\u7cfb\u7d71\u4e2d\u6700\u9ad8\uff0c\u9023\u5728\u751f\u9577\u5b63\u7bc0\u7684\u690d\u7269\u4e5f\u53ea\u67091.4%-2.0%\u800c\u5df2\u5462\uff01\u7531\u65bc\u7570\u4e19\u9187\u53ef\u4ee5\u7528\u65bc\u5167\u71c3\u6a5f\uff0c\u5bb9\u6613\u5132\u5b58\u8207\u904b\u8f38\uff0c\u6240\u4ee5\u9019\u500b\u6539\u826f\u53ef\u8aaa\u662f\u751f\u8cea\u80fd\u6e90\u7684\u5927\u9032\u6b65\u3002<\/p>\n<p>\u904e\u53bb\u55ae\u7d14\u7684\u4f7f\u7528\u592a\u967d\u80fd\u767c\u96fb\uff0c\u7531\u65bc\u96fb\u80fd\u53ea\u80fd\u77ed\u6642\u9593\u5132\u5b58\uff08\u96fb\u6c60\uff09\uff0c\u9020\u6210\u4e00\u5b9a\u7a0b\u5ea6\u7684\u6d6a\u8cbb\uff1b\u5982\u80fd\u6709\u5c07\u5149\u80fd\u8f49\u63db\u70ba\u5316\u5b78\u80fd\uff08\u5982\u5149\u5408\u4f5c\u7528\uff09\u7684\u65b9\u6cd5\uff0c\u4fbf\u53ef\u4ee5\u5c07\u5149\u80fd\u5132\u5b58\u8d77\u4f86\u3002\u904e\u53bb\u8a31\u591a\u8f49\u63db\u7684\u65b9\u5f0f\uff0c\u82e5\u4e0d\u662f\u5132\u5b58\u56f0\u96e3\uff08\u6c2b\u6c23\uff09\uff0c\u4fbf\u662f\u53ea\u80fd\u5c0f\u91cf\u65bd\u4f5c\uff0c\u7121\u6cd5\u64f4\u5927\u3002\u73fe\u5728\u54c8\u4f5b\u958b\u767c\u7684\u65b9\u6cd5\uff0c\u53ef\u4ee5\u5c07\u5149\u80fd\u4ee5\u5316\u5b78\u80fd\u7684\u65b9\u5f0f\u5132\u5b58\u8d77\u4f86\uff0c\u53c8\u80fd\u64f4\u5927\u65bd\u4f5c\uff0c\u7522\u751f\u7684\u5316\u5b78\u80fd\u9084\u53ef\u76f4\u63a5\u7528\u65bc\u5167\u71c3\u6a5f\u3002\u96d6\u7136\u7570\u4e19\u9187\u71c3\u71d2\u6703\u7522\u751f\u4e8c\u6c27\u5316\u78b3\uff0c\u4f46\u9019\u500b\u65b9\u6cd5\u6240\u7522\u88fd\u7684\u7570\u4e19\u9187\u4e5f\u662f\u7531\u4e8c\u6c27\u5316\u78b3\u800c\u4f86\uff0c\u69cb\u6210\u4e86\u4e00\u500b\u5b8c\u6574\u7684\u5faa\u74b0\u3002\u771f\u7684\u975e\u5e38\u4ee4\u4eba\u671f\u5f85\u5462\uff01<\/p>\n<p><strong>\u53c3\u8003\u6587\u737b\uff1a<\/strong><br \/>\n1.\u00a0<a href=\"http:\/\/en.wikipedia.org\/wiki\/Hydrogen\">Hydrogen<\/a>.<br \/>\n2. Han Li, Paul H. Opgenorth, David G. Wernick, Steve Rogers, Tung-Yun Wu, Wendy Higashide, Peter Malati, Yi-Xin Huo, Kwang Myung Cho, James C. Liao. 2012.<a href=\"http:\/\/www.sciencemag.org\/content\/335\/6076\/1596.full?sid=95b82286-777c-45d7-be00-86558b20706e\">\u00a0Integrated Electromicrobial Conversion of CO2 to Higher Alcohols<\/a>. Science. 335:1596<br \/>\n3. Joseph P. Torella, Christopher J. Gagliardi, Janice S. Chen, D. Kwabena Bediako, Brendan Col\u00f3n, Jeffery C. Way, Pamela A. Silver, and Daniel G. Nocera. 2015.\u00a0<a href=\"http:\/\/www.pnas.org\/content\/early\/2015\/02\/06\/1424872112.abstract\">Efficient solar-to-fuels production from a hybrid microbial\u2013water-splitting catalyst system<\/a>. Proc. Natl. Acad. Sci. USA. doi: 10.1073\/pnas.1424872112<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/line.me\/R\/ti\/p\/%40fcx6182w\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/zh-Hant.png\" alt=\"\u52a0\u5165\u597d\u53cb\" width=\"212\" height=\"36\" border=\"0\"><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0\u54c8\u4f5b\u7814\u7a76\u5718\u968a\u7d50\u5408\u592a\u967d\u80fd\u96fb\u6c60(\u6216\u7a31\u592a\u967d\u80fd<\/p>\n","protected":false},"author":20,"featured_media":20985,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32,191,1023,3293],"tags":[1715,1710,1714,214,361,1543],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2015\/03\/F1.large_.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/20984"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=20984"}],"version-history":[{"count":5,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/20984\/revisions"}],"predecessor-version":[{"id":32219,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/20984\/revisions\/32219"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/20985"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=20984"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=20984"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=20984"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}