{"id":19357,"date":"2014-10-07T09:00:23","date_gmt":"2014-10-07T01:00:23","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=19357"},"modified":"2017-03-31T23:16:51","modified_gmt":"2017-03-31T15:16:51","slug":"%e3%80%90%e6%99%82%e4%ba%8b%e7%84%a6%e9%bb%9e%e3%80%912014%e5%b9%b4%e8%ab%be%e8%b2%9d%e7%88%be%e7%94%9f%e9%86%ab%e7%8d%8e%ef%bc%8d%e7%99%bc%e7%8f%be%e5%a4%a7%e8%85%a6%e8%a3%a1%e7%a9%ba%e9%96%93","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=19357","title":{"rendered":"\u3010\u6642\u4e8b\u7126\u9ede\u30112014\u5e74\u8afe\u8c9d\u723e\u751f\u91ab\u734e\uff0d\u767c\u73fe\u5927\u8166\u88e1\u7a7a\u9593\u8a18\u61b6\u7684\u69cb\u7bc9\u7d30\u80de"},"content":{"rendered":"<p><span style=\"color: #333399;\"><strong>\u25a0\u7f8e\u570b\u8207\u82f1\u570b\u96d9\u91cd\u570b\u7c4d\u7684John O\u2019Keefe\u3001\u632a\u5a01\u7684May\u2010Britt Moser\u53caEdvard I. Moser\u592b\u5a66\uff0c\u4e09\u4eba\u56e0\u767c\u73fe\u5927\u8166\u5b9a\u4f4d\u7cfb\u7d71\u7684\u795e\u7d93\u7d30\u80de\uff0c\u5171\u540c\u7372\u5f972014\u5e74\u8afe\u8c9d\u723e\u751f\u7406\u8207\u91ab\u5b78\u734e\u3002<\/strong><\/span><br \/>\n<img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter wp-image-19358\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/10\/nobel.png\" alt=\"nobel\" width=\"650\" height=\"302\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/10\/nobel.png 791w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/10\/nobel-300x139.png 300w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/10\/nobel-600x279.png 600w\" sizes=\"(max-width: 650px) 100vw, 650px\" \/><strong>\u7de8\u8b6f\uff5c<\/strong>\u8303\u59dc\u6587\u69ae<\/p>\n<p>\u6211\u5011\u5982\u4f55\u77e5\u9053\u4f4d\u5728\u4f55\u8655?\u5982\u4f55\u627e\u5230\u5f9e\u4e00\u500b\u5730\u9ede\u5230\u53e6\u4e00\u5730\u9ede\u7684\u8def\u5f91?\u5982\u4f55\u80fd\u5132\u5b58\u9019\u4e9b\u8a0a\u606f\uff0c\u4ee5\u4fbf\u4e0b\u6b21\u80fd\u8fc5\u901f\u627e\u5230\u76f8\u540c\u8def\u5f91?\u4eca\u5e74\u7684\u8afe\u8c9d\u723e\u751f\u7406\u8207\u91ab\u5b78\u734e\u5f97\u4e3b\uff0c\u4ed6\u5011\u767c\u73fe\u5927\u8166\u5167\u90e8GPS\uff0c\u4f7f\u6211\u5011\u80fd\u5b9a\u4f4d\u7a7a\u9593\u6240\u5728\u4f4d\u7f6e\uff0c\u4e26\u8b49\u5be6\u8166\u90e8\u6709\u4e9b\u795e\u7d93\u7d30\u80de\uff0c\u8ca0\u8cac\u9ad8\u968e\u8a8d\u77e5\u529f\u80fd\u3002<\/p>\n<p>\u96d6\u7136\u904e\u53bbEdward Tolman\u767c\u73fe\u5728\u8ff7\u5bae(labyrinths)\u4e2d\u79fb\u52d5\u7684\u5927\u9f20\uff0c\u80fd\u5920\u5b78\u7fd2\u5230\u5982\u4f55\u627e\u5230\u6b63\u78ba\u8def\u5f91\uff0c\u4e26\u63a8\u6e2c\u5927\u9f20\u8166\u5167\u6709\u8a8d\u77e5\u8f2a\u5ed3\u5716\uff0c\u8b93\u5b83\u627e\u5230\u6b63\u78ba\u8def\u5f91\uff0c\u4f46\u662f\u9577\u4e45\u4ee5\u4f86\uff0c\u5c0d\u65bc\u5927\u8166\u5982\u4f55\u5efa\u7f6e\u6b64\u7a7a\u9593\u8f2a\u5ed3\u5716\u4ecd\u662f\u672a\u77e5\u3002<!--more--><\/p>\n<figure id=\"attachment_19359\" aria-describedby=\"caption-attachment-19359\" style=\"width: 490px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-19359 size-full\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/10\/nobel2.png\" alt=\"nobel2\" width=\"490\" height=\"292\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/10\/nobel2.png 490w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/10\/nobel2-300x178.png 300w\" sizes=\"(max-width: 490px) 100vw, 490px\" \/><figcaption id=\"caption-attachment-19359\" class=\"wp-caption-text\">2014\u8afe\u8c9d\u723e\u751f\u91ab\u734e\u5f97\u734e\u8005<\/figcaption><\/figure>\n<p>John O\u2019Keefe\u65bc1971\u5e74\uff0c\u9996\u5148\u767c\u73fe\u8166\u90e8\u5b9a\u4f4d\u7cfb\u7d71\u7d44\u6210\uff0c\u4ed6\u767c\u73fe\u7576\u5927\u9f20\u5728\u623f\u9593\u67d0\u7279\u5b9a\u4f4d\u7f6e\uff0c\u9f20\u8166\u67d0\u7279\u5b9a\u5340\u57df-\u6d77\u99ac\u8ff4(hippocampus)\u7684\u4e00\u985e\u795e\u7d93\u7d30\u80de(a type of nerve cell)\uff0c\u7e3d\u662f\u88ab\u6d3b\u5316\u3002\u7576\u5927\u9f20\u88ab\u79fb\u81f3\u5176\u5b83\u4f4d\u7f6e\uff0c\u5247\u6d3b\u5316\u5176\u5b83\u795e\u7d93\u7d30\u80de\u3002John O\u2019Keefe\u8a8d\u70ba\u9019\u4e9b\u4f4d\u7f6e\u7d30\u80de(place cells)\u5f62\u6210\u623f\u9593\u7684\u7a7a\u9593\u8f2a\u5ed3\u3002<\/p>\n<p>\u7d93\u904e30\u5e74\u5f8c\uff0c\u57282005\u5e74\uff0cMay\u2010Britt Moser\u53caEdvard I. Moser\u592b\u5a66\u767c\u73fe\u53e6\u4e00\u8166\u90e8\u5b9a\u4f4d\u7cfb\u7d71\u7684\u91cd\u8981\u7d44\u6210\u3002\u4ed6\u5011\u8fa8\u8b58\u51fa\u53e6\u4e00\u985e\u795e\u7d93\u7d30\u80de-\u7db2\u683c\u7d30\u80de(grid cells)\uff0c\u9019\u4e9b\u7d30\u80de\u80fd\u7522\u751f\u5ea7\u6a19\u7cfb\u7d71\uff0c\u4e26\u8ca0\u8cac\u6b63\u78ba\u5b9a\u4f4d\u53ca\u8def\u5f91\u5c0b\u627e\u3002\u4ed6\u5011\u7684\u7814\u7a76\u8b49\u5be6\uff0c\u4f4d\u7f6e\u7d30\u80de\u8207\u7db2\u683c\u7d30\u80de\uff0c\u5982\u4f55\u80fd\u53bb\u5b9a\u4f4d\u53ca\u5c0e\u5f15\u8def\u5f91\u3002<\/p>\n<p>John O\u2019Keefe\u3001May\u2010Britt Moser\u53caEdvard I. Moser\uff0c\u4e09\u4eba\u7684\u767c\u73fe\u89e3\u6c7a\u767e\u5e74\u4ee5\u4f86\uff0c\u4e00\u76f4\u56f0\u64fe\u54f2\u5b78\u5bb6\u53ca\u79d1\u5b78\u5bb6\u7684\u7591\u554f\uff0c\u5927\u8166\u662f\u5982\u4f55\u5efa\u7f6e\u74b0\u7e5e\u81ea\u8eab\u7684\u7a7a\u9593\u8f2a\u5ed3\u5716\uff0c\u4ee5\u53ca\u6211\u5011\u662f\u5982\u4f55\u5728\u8907\u96dc\u7684\u74b0\u5883\uff0c\u627e\u5230\u5c0e\u5f15\u7684\u8def\u5f91\u3002<\/p>\n<p><strong>John O\u2019Keefe<\/strong><strong>\u8207\u7a7a\u9593\u4f4d\u7f6e<br \/>\n<\/strong>John O\u2019Keefe\u8457\u8ff7\u5c0d\u5927\u8166\u5982\u4f55\u63a7\u5236\u884c\u70ba\u8207\u505a\u51fa\u6c7a\u5b9a\u7684\u554f\u984c\uff0c\u57281960\u5e74\uff0c\u5617\u8a66\u4f7f\u7528\u795e\u7d93\u751f\u7406\u5b78\u7684\u65b9\u6cd5\u4f86\u63a2\u7d22\u6b64\u554f\u984c\uff0c\u5373\u85c9\u7531\u7d00\u9304\u5728\u623f\u9593\u5167\u81ea\u7531\u904b\u52d5\u7684\u5927\u9f20\uff0c\u5176\u5927\u8166\u6d77\u99ac\u8ff4\u5340\u7684\u500b\u5225\u795e\u7d93\u7d30\u80de\u8a0a\u865f\u3002\u4ed6\u767c\u73fe\u7576\u5927\u9f20\u5728\u74b0\u5883\u7279\u5b9a\u4f4d\u7f6e\uff0c\u67d0\u4e00\u795e\u7d93\u7d30\u80de\u6703\u88ab\u6d3b\u5316\u3002\u4ed6\u8b49\u5be6\u9019\u4e9b\u795e\u7d93\u7d30\u80de-\u4f4d\u7f6e\u7d30\u80de\uff0c\u4e0d\u50c5\u80fd\u8a18\u9304\u8996\u89ba\u8f38\u5165\uff0c\u4e26\u4e14\u80fd\u5efa\u7f6e\u74b0\u5883\u5167\u90e8\u8f2a\u5ed3\u3002John O\u2019Keefe\u8a8d\u70ba\u5927\u8166\u6d77\u99ac\u8ff4\u5340\uff0c\u88ab\u6d3b\u5316\u7684\u4f4d\u7f6e\u7d30\u80de\uff0c\u80fd\u5f59\u6574\u80fd\u7522\u751f\u7121\u6578\u7684\u7a7a\u9593\u4f4d\u7f6e\u8f2a\u5ed3\u5716\uff0c\u56e0\u6b64\u67d0\u74b0\u5883\u7a7a\u9593\u7684\u8a18\u61b6\uff0c\u80fd\u88ab\u5132\u5b58\u5728\u4f4d\u7f6e\u7d30\u80de\u6a5f\u80fd\u7684\u7279\u5b9a\u6574\u5408\u3002<\/p>\n<p><strong>May\u2010Britt Moser<\/strong><strong>\u53caEdvard I. Moser<\/strong><strong>\u767c\u73fe\u5ea7\u6a19\u7cfb\u7d71<br \/>\n<\/strong>May\u2010Britt Moser\u53caEdvard I. Moser\u5728\u5927\u8166\u5167\u55c5\u76ae\u8cea(entorhinal cortex)\uff0c\u6709\u4ee4\u4eba\u9a5a\u8a1d\u7684\u7d30\u80de\u6d3b\u52d5\u6a21\u5f0f\uff0c\u4ed6\u5011\u767c\u73fe\u7576\u5927\u9f20\u901a\u904e\u516d\u89d2\u5f62\u7684\u7db2\u683c\u8def\u5f91\u591a\u91cd\u4f4d\u7f6e\uff0c\u67d0\u4e9b\u7d30\u80de\u6703\u88ab\u6d3b\u5316\u3002\u6b64\u6bcf\u4e00\u7d30\u80de\u6703\u53d7\u5230\u7279\u5b9a\u7a7a\u9593\u6a21\u5f0f\u7684\u6d3b\u5316\uff0c\u9019\u4e9b\u7d30\u80de\u5408\u7a31\u70ba\u7db2\u683c\u7d30\u80de(grid cells)\uff0c\u5efa\u69cb\u5ea7\u6a19\u7cfb\u7d71\uff0c\u8ca0\u8cac\u7a7a\u9593\u5c0e\u822a\u3002\u4e26\u8207\u80fd\u8fa8\u8b58\u6240\u5728\u65b9\u4f4d\u53ca\u623f\u9593\u7684\u754c\u7dda\u7684\u5167\u55c5\u76ae\u8cea\u5176\u4ed6\u7d30\u80de\u5408\u4f5c\uff0c\u8207\u6d77\u99ac\u8ff4\u5340\u7684\u4f4d\u7f6e\u7d30\u80de\uff0c\u5171\u540c\u5f62\u6210\u7a7a\u9593\u8def\u7dda\u5716\u3002\u6b64\u7a7a\u9593\u8def\u7dda\u8ff4\u8def\uff0c\u5efa\u7f6e\u8166\u5167\u8907\u96dc\u7684\u4f4d\u7f6e\u7cfb\u7d71-\u8166\u5167GPS\u3002<\/p>\n<p>\u4e09\u4eba\u7684\u5728\u5927\u8166\u4f4d\u7f6e\u7cfb\u7d71\u9818\u57df\u7684\u524d\u77bb\u6027\u7814\u7a76\uff0c\u6709\u52a9\u65bc\u6211\u5011\u53bb\u7406\u89e3\u7a7a\u9593\u8a18\u61b6\u55aa\u5931\u7684\u6a5f\u5236\uff0c\u4ee5\u53ca\u5c0b\u627e\u6b64\u985e\u75be\u75c5\u7684\u6cbb\u7642\u65b9\u5f0f\u3002\u4e5f\u958b\u555f\u4eba\u985e\u77ad\u89e3\u5176\u5b83\u8a8d\u77e5\u904e\u7a0b\uff0c\u5982\u8a18\u61b6\u3001\u601d\u8003\u3001\u53ca\u898f\u5283\u7684\u65b0\u65b9\u5411\u3002<\/p>\n<p><strong><span style=\"color: #222222;\">--<br \/>\n\u7814\u7a76\u51fa\u8655\uff1a<\/span><\/strong><span style=\"color: #222222;\"><a href=\"http:\/\/www.nobelprize.org\/nobel_prizes\/medicine\/laureates\/2014\/press.html\" target=\"_blank\">The Nobel Prize in Physiology or Medicine 2014<\/a><\/span><strong><span style=\"color: #222222;\"><br \/>\n\u5f97\u734e\u8005\u7167\u7247\uff1a<\/span><\/strong><a style=\"color: #1155cc;\" href=\"http:\/\/www.nobelprize.org\/nobel_prizes\/medicine\/laureates\/2014\/\" target=\"_blank\">http:\/\/www.nobelprize.<wbr \/>org\/nobel_prizes\/medicine\/<wbr \/>laureates\/2014\/<\/a><br style=\"color: #222222;\" \/><strong><span style=\"color: #222222;\">\u7814\u7a76\u7c21\u4ecb\u5716\uff1a<\/span><\/strong><a style=\"color: #1155cc;\" href=\"http:\/\/www.nobelprize.org\/nobel_prizes\/medicine\/laureates\/2014\/med_image_press_eng.pdf\" target=\"_blank\">http:\/\/www.nobelprize.<wbr \/>org\/nobel_prizes\/medicine\/<wbr \/>laureates\/2014\/med_image_<wbr \/>press_eng.pdf<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0\u7f8e\u570b\u8207\u82f1\u570b\u96d9\u91cd\u570b\u7c4d\u7684John O\u2019Ke<\/p>\n","protected":false},"author":20,"featured_media":19358,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1027,3293,22,1025],"tags":[1639,116,1455,177,1454],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/10\/nobel.png","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/19357"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=19357"}],"version-history":[{"count":7,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/19357\/revisions"}],"predecessor-version":[{"id":19366,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/19357\/revisions\/19366"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/19358"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=19357"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=19357"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=19357"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}