{"id":18783,"date":"2014-08-20T02:17:44","date_gmt":"2014-08-19T18:17:44","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=18783"},"modified":"2017-07-25T11:35:57","modified_gmt":"2017-07-25T03:35:57","slug":"%e3%80%90%e9%86%ab%e5%ad%b8%e6%8a%80%e8%a1%93%e3%80%91%e9%81%8b%e7%94%a8%e5%9f%ba%e5%9b%a0%e7%99%82%e6%b3%95%ef%bc%8c%e9%96%8b%e7%99%bc%e5%87%ba%e7%94%9f%e7%89%a9%e5%bf%83%e5%be%8b%e8%aa%bf%e7%af%80","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=18783","title":{"rendered":"\u3010\u91ab\u5b78\u6280\u8853\u3011\u904b\u7528\u57fa\u56e0\u7642\u6cd5\uff0c\u958b\u767c\u51fa\u751f\u7269\u5fc3\u5f8b\u8abf\u7bc0\u5668"},"content":{"rendered":"<p><span style=\"color: #333399;\"><strong><strong>\u25a0<\/strong>\u7814\u7a76\u4eba\u54e1\u904b\u7528\u57fa\u56e0\u7642\u6cd5\uff0c\u91cd\u65b0\u7de8\u7a0b\u5fc3\u81df\u808c\u8089\u7d30\u80de\uff0c\u4f7f\u5176\u767c\u63ee\u300c\u751f\u7269\u5fc3\u5f8b\u8abf\u7bc0\u5668\u300d\u7684\u529f\u80fd\uff0c\u6210\u529f\u5730\u8b93\u5fc3\u5f8b\u4e0d\u6574\u7684\u8c6c\u96bb\u66ab\u6642\u6062\u5fa9\u6b63\u5e38\u5fc3\u8df3\u3002\u6b64\u7814\u7a76\u767c\u73fe\u610f\u5473\u8457\uff0c\u672a\u4f86\u9664\u4e86\u96fb\u5b50\u5fc3\u5f8b\u8abf\u7bc0\u5668\u4e4b\u5916\uff0c\u60a3\u8005\u53ef\u80fd\u6709\u591a\u4e00\u7a2e\u9078\u64c7\u3002<\/strong><\/span><\/p>\n<figure id=\"attachment_18785\" aria-describedby=\"caption-attachment-18785\" style=\"width: 400px\" class=\"wp-caption alignleft\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-18785\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/08\/2015221291_aedeba438a_o.jpg\" alt=\"\u7167\u7247\uff5cSteve Winton\" width=\"400\" height=\"266\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/08\/2015221291_aedeba438a_o.jpg 640w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/08\/2015221291_aedeba438a_o-300x199.jpg 300w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/08\/2015221291_aedeba438a_o-600x398.jpg 600w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><figcaption id=\"caption-attachment-18785\" class=\"wp-caption-text\">\u7167\u7247\uff5cSteve Winton<\/figcaption><\/figure>\n<p><strong>\u7de8\u8b6f\uff5c<\/strong>\u5289\u8ce2\u54f2<\/p>\n<p><a href=\"http:\/\/hyperphysics.phy-astr.gsu.edu\/hbase\/biology\/sanode.html\" target=\"_blank\" rel=\"noopener noreferrer\">\u7ac7\u623f\u7d50<\/a>\u4f4d\u65bc\u53f3\u5fc3\u623f\uff0c\u662f\u4e00\u7a2e\u7279\u5316\u7d30\u80de\uff0c\u6703\u5b9a\u6642\u767c\u5c04\u96fb\u8108\u885d\u5f15\u8d77\u5fc3\u81df\u808c\u8089\u6536\u7e2e\uff0c\u85c9\u6b64\u5c07\u8840\u6db2\u8f38\u9001\u81f3\u5168\u8eab\uff0c\u56e0\u6b64\u6709\u5929\u7136\u7684\u5fc3\u5f8b\u8abf\u7bc0\u5668\u4e4b\u7a31\u3002<\/p>\n<p>\u67d0\u60a3\u8005\u7684\u7ac7\u623f\u7d50\u7121\u6cd5\u767c\u63ee\u529f\u80fd\uff0c\u5c0e\u81f4\u5fc3\u5f8b\u6e1b\u7de9\u6216\u767c\u751f\u7570\u5e38\uff0c\u56e0\u6b64\u9700\u8981\u5b89\u88dd\u96fb\u5b50\u5fc3\u5f8b\u8abf\u7bc0\u5668\u4ee5\u6062\u5fa9\u6b63\u5e38\u5fc3\u5f8b\u3002\u96d6\u7136\u96fb\u5b50\u5fc3\u5f8b\u8abf\u7bc0\u5668\u78ba\u5be6\u6709\u6548\uff0c\u4f46\u56e0\u70ba\u5b89\u88dd\u6642\u9700\u5be6\u65bd\u4fb5\u5165\u6027\u624b\u8853\uff0c\u52a0\u4e0a\u6709\u4e9b\u8abf\u7bc0\u5668\u6703\u56e0\u70ba\u6545\u969c\u800c\u9700\u8981\u66f4\u63db\uff0c\u6240\u4ee5\u60a3\u8005\u4e5f\u9762\u81e8\u611f\u67d3\u7684\u98a8\u96aa\u3002\u56e0\u6b64\uff0c\u5404\u65b9\u975e\u5e38\u6a02\u898b\u672a\u4f86\u80fd\u6709\u5176\u4ed6\u9078\u64c7\uff0c\u9019\u4e5f\u662f\u611b\u83ef\u591a\u00b7\u99ac\u723e\u73ed(Eduardo Marb\u00e1n)\u7814\u7a76\u5718\u968a\u4e00\u76f4\u4ee5\u4f86\u52aa\u529b\u7684\u65b9\u5411\u3002<!--more--><\/p>\n<p>\u7814\u7a76\u4eba\u54e1\u5148\u904b\u7528\u9ad8\u983b\u7121\u7dda\u96fb\u6ce2\u6467\u6bc012\u96bb\u8c6c\u8eab\u4e0a\u7684\u7ac7\u623f\u7d50\u5fc3\u5f8b\u8abf\u7bc0\u7d30\u80de\uff0c\u8b93\u96fb\u5b50\u8a0a\u865f\u7121\u6cd5\u50b3\u905e\u81f3\u6574\u9846\u5fc3\u81df\uff0c\u4f7f\u8c6c\u96bb\u7684\u5fc3\u8df3\u5f9e\u6bcf\u5206\u9418 100 \u4e0b\u6e1b\u5c11\u81f3\u7d04 50 \u4e0b\uff0c\u85c9\u6b64\u6a21\u64ec\u56b4\u91cd\u7684\u4eba\u985e\u5fc3\u81df\u75be\u75c5\u2013<a href=\"http:\/\/www.washingtonpost.com\/national\/health-science\/gene-therapy-can-reprogram-heart-muscle-cells-to-act-as-biological-pacemaker\/2014\/07\/16\/6de7e116-0c52-11e4-8c9a-923ecc0c7d23_story.html\" target=\"_blank\" rel=\"noopener noreferrer\">\u5fc3\u50b3\u5c0e\u963b\u6eef<\/a>\u3002\u63a5\u8457\uff0c\u4ed6\u5011\u5728\u8c6c\u7684\u5fc3\u81df\u6ce8\u5c04\u4e86\u651c\u5e36<em>TBX18<\/em>\u57fa\u56e0\u6216<a href=\"http:\/\/www.washingtonpost.com\/national\/health-science\/gene-therapy-can-reprogram-heart-muscle-cells-to-act-as-biological-pacemaker\/2014\/07\/16\/6de7e116-0c52-11e4-8c9a-923ecc0c7d23_story.html\" target=\"_blank\" rel=\"noopener noreferrer\">\u87a2\u5149\u86cb\u767d\u8cea<\/a>\u7684\u817a\u75c5\u6bd2\u3002<\/p>\n<p>\u5169\u5929\u5167\uff0c\u906d\u611f\u67d3\u7684\u5fc3\u81df\u7d30\u80de\u958b\u59cb\u8868\u73fe\u51fa\u5fc3\u5f8b\u8abf\u7bc0\u57fa\u56e0\u3002\u63a5\u4e0b\u4f86\uff0c\u7814\u7a76\u4eba\u54e1\u76e3\u63a7\u8c6c\u96bb\u9032\u884c\u4e0d\u540c\u6d3b\u52d5\u6642\u7684\u5fc3\u5f8b\uff0c\u85c9\u6b64\u78ba\u4fdd\u65b0\u7d30\u80de\u78ba\u5be6\u80fd\u5920\u8abf\u7bc0\u5fc3\u5f8b\uff0c\u8b93\u8c6c\u96bb\u9032\u884c\u65e5\u5e38\u6d3b\u52d5\u3002\u4ed6\u5011\u767c\u73fe\uff0c\u7121\u8ad6\u8c6c\u96bb\u9032\u884c\u4ec0\u9ebc\u6d3b\u52d5\uff0c\u751f\u7269\u5fc3\u5f8b\u8abf\u7bc0\u5668\u53ef\u4ee5\u767c\u63ee\u5169\u9031\u7684\u529f\u6548\uff1b\u6ce8\u5c04<em>TBX18<\/em>\u57fa\u56e0\u7684\u8c6c\u96bb\uff0c\u5fc3\u8df3\u9060\u9ad8\u65bc\u6ce8\u5c04\u87a2\u5149\u86cb\u767d\u8cea\u7684\u8c6c\u96bb\u3002<\/p>\n<p>\u99ac\u723e\u73ed\u8868\u793a\uff0c\u96d6\u7136\u9019\u7a2e\u6280\u8853\u6bd4\u76ee\u524d\u5176\u4ed6\u7d93\u904e\u6e2c\u8a66\u7684\u751f\u7269\u65b9\u5f0f\u7c21\u4fbf\uff0c\u4f46\u6548\u679c\u53ef\u80fd\u53ea\u662f\u66ab\u6642\u7684\uff0c\u9019\u662f\u56e0\u70ba\u514d\u75ab\u7cfb\u7d71\u6703\u9010\u6f38\u958b\u59cb\u653b\u64ca\u53d7\u75c5\u6bd2\u611f\u67d3\u7684\u7d30\u80de\u3002<\/p>\n<p>\u96d6\u7136\u6b64\u6280\u8853\u76ee\u524d\u7684\u7528\u9014\u6709\u9650\uff0c\u4f46\u6216\u8a31\u80fd\u66ab\u6642\u89e3\u6c7a\u67d0\u4e9b\u554f\u984c\uff0c\u5982\u6cbb\u7642\u5fc3\u81df\u6709\u7f3a\u9677\u4f46\u7121\u6cd5\u5b89\u88dd\u5fc3\u5f8b\u8abf\u7bc0\u5668\u7684\u80ce\u5152\uff0c\u6216\u662f\u6210\u9577\u975e\u5e38\u5feb\u800c\u9700\u8981\u7d93\u5e38\u66f4\u63db\u5fc3\u5f8b\u8abf\u7bc0\u5668\u7684\u5152\u7ae5\u3002\u7814\u7a76\u5718\u968a\u9810\u6e2c\uff0c\u5982\u679c\u6280\u8853\u7d93 FDA \u6838\u51c6\uff0c\u4eba\u9ad4\u8a66\u9a57\u6700\u5feb\u53ef\u5728 2 \u81f3 3 \u5e74\u5167\u5c55\u958b\u3002<br \/>\n--<br \/>\n<span style=\"color: #333333;\"><strong> \u7814\u7a76\u51fa\u8655\uff1a<a href=\"http:\/\/www.iflscience.com\/health-and-medicine\/biological-pacemaker-developed-using-gene-therapy\" target=\"_blank\" rel=\"noopener noreferrer\">Biological Pacemaker Developed Using Gene Therapy<\/a><\/strong><\/span><br \/>\n<span style=\"color: #333399;\"><strong><strong>\u8b6f\u8005\uff1a\u5289\u8ce2\u54f2 \u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b\uff0c\u5f9e\u4e8b\u79d1\u666e\u6587\u7ae0\u7de8\u8b6f\u3002<\/strong><\/strong><\/span><br \/>\n<span style=\"color: #333399;\"><strong><strong>\u8cac\u4efb\u7de8\u8f2f\uff1aKerina Huang<\/strong><\/strong><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0\u7814\u7a76\u4eba\u54e1\u904b\u7528\u57fa\u56e0\u7642\u6cd5\uff0c\u91cd\u65b0\u7de8\u7a0b\u5fc3\u81df\u808c\u8089<\/p>\n","protected":false},"author":20,"featured_media":18785,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3293,1025],"tags":[129,1367,727],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/08\/2015221291_aedeba438a_o.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/18783"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18783"}],"version-history":[{"count":7,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/18783\/revisions"}],"predecessor-version":[{"id":28797,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/18783\/revisions\/28797"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/18785"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18783"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18783"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18783"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}