{"id":17196,"date":"2014-04-28T05:00:19","date_gmt":"2014-04-27T21:00:19","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=17196"},"modified":"2017-07-27T09:59:40","modified_gmt":"2017-07-27T01:59:40","slug":"%e3%80%90%e5%bf%83%e7%90%86%e6%b2%bb%e7%99%82%e3%80%91%e6%b2%bb%e7%99%82%e8%97%a5%e4%b8%8d%e8%97%a5%ef%bc%9f%e7%b2%be%e7%a5%9e%e5%88%86%e8%a3%82%e7%97%87%e7%9a%84%e6%96%b0%e7%99%82%e6%b3%95","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=17196","title":{"rendered":"\u3010\u5fc3\u7406\u6cbb\u7642\u3011\u6cbb\u7642\u85e5\u4e0d\u85e5\uff1f\u601d\u89ba\u5931\u8abf\u75c7\u7684\u65b0\u7642\u6cd5"},"content":{"rendered":"<p><span style=\"color: #333399;\"><strong>\u25a0\u601d\u89ba\u5931\u8abf\u75c7(Schizophrenia)\u5e36\u7d66\u60a3\u8005\u5011\u7684\u8a31\u591a\u751f\u6d3b\u4e0a\u7684\u4e0d\u4fbf\uff0c\u4e0d\u50c5\u8b93\u4ed6\u5011\u7121\u6cd5\u6b63\u5e38\u5de5\u4f5c\uff0c\u751a\u81f3\u6703\u5f71\u97ff\u4e00\u822c\u793e\u4ea4\u4e92\u52d5\u53ca\u4eba\u969b\u95dc\u4fc2\u3002\u901a\u5e38\uff0c\u91ab\u5e2b\u90fd\u6703\u958b\u7d66\u75c5\u60a3\u6297\u7cbe\u795e\u75c5\u85e5\u7269\uff0c\u4f46\u9019\u7a2e\u85e5\u7269\u6216\u591a\u6216\u5c11\u90fd\u6703\u5e36\u4f86\u56b4\u91cd\u7684\u526f\u4f5c\u7528\u3002\u6700\u8fd1\u4e00\u9805\u7814\u7a76\u6307\u51fa\uff0c\u91dd\u5c0d\u4e0d\u80fd\u6216\u662f\u4e0d\u60f3\u670d\u7528\u85e5\u7269\u4f86\u6cbb\u7642\u7684\u75c5\u60a3\uff0c\u5fc3\u7406\u6cbb\u7642\u6cd5\u6216\u8a31\u80fd\u6210\u70ba\u4e00\u66ff\u4ee3\u65b9\u6848\u3002<\/strong><\/span><\/p>\n<figure id=\"attachment_17198\" aria-describedby=\"caption-attachment-17198\" style=\"width: 389px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/04\/sn-schizophrenia-2.jpg\"><img fetchpriority=\"high\" decoding=\"async\" class=\" wp-image-17198\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/04\/sn-schizophrenia-2.jpg\" alt=\"sn-schizophrenia (2)\" width=\"389\" height=\"393\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/04\/sn-schizophrenia-2.jpg 600w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/04\/sn-schizophrenia-2-296x300.jpg 296w\" sizes=\"(max-width: 389px) 100vw, 389px\" \/><\/a><figcaption id=\"caption-attachment-17198\" class=\"wp-caption-text\">\u601d\u89ba\u5931\u8abf\u75c7\u75c5\u60a3\u7684\u65b0\u5e0c\u671b\uff1f<br \/> \u5982\u540c\u6b64\u756b\u5bb6\u6240\u8a6e\u91cb\u7684\uff0c\u601d\u89ba\u5931\u8abf\u75c7\u5c31\u50cf\u662f\u4e00\u5834\u9192\u8457\u7684\u5922\u9b58\u3002<\/figcaption><\/figure>\n<p><b>\u4f5c\u8005<\/b><b>\uff5c<\/b>Michael Balter<b><br \/>\n<\/b><b>\u7de8\u8b6f\uff5c<\/b><b><\/b>\u6797\u6021\u5fb7<\/p>\n<p>\u601d\u89ba\u5931\u8abf\u75c7\u7684\u60a3\u8005\u6703\u6709\u5e7b\u89ba(hallucination)\u3001\u5984\u60f3(delusion)\u3001\u5fc3\u7406\u969c\u7919\u548c\u5176\u4ed6\u56b4\u91cd\u7684\u75c7\u72c0\uff0c\u5f71\u97ff\u5176\u65e5\u5e38\u751f\u6d3b\u3002\u96d6\u7136\u73fe\u5728\u5e02\u9762\u4e0a\u6709\u7406\u5fc5\u601d\u59a5(Risperidone)\u3001\u597d\u5ea6\u6db2(haloperidol)\u3001\u53ef\u81f4\u5f8b\u9320(clozapine)\u7b49\u8d85\u904e20\u591a\u7a2e\u7684\u6297\u7cbe\u795e\u75c5\u85e5\u7269\uff0c\u4e14\u5728\u77ed\u671f\u7642\u7a0b\u5167\u90fd\u53ef\u6709\u6548\u7d13\u7de9\u75c7\u72c0\uff0c\u4f46\u5982\u7642\u7a0b\u5ef6\u9577\uff0c\u9019\u4e9b\u85e5\u7269\u53ef\u80fd\u6703\u958b\u59cb\u7522\u751f\u526f\u4f5c\u7528\uff0c\u50cf\u662f\u808c\u8089\u52d5\u4f5c\u5931\u8abf\u3001\u9ad4\u91cd\u66b4\u589e\u3001\u5fc3\u81df\u75c5\u7b49\u3002\u8fd1\u5e7e\u5e74\uff0c\u7cbe\u795e\u79d1\u91ab\u5e2b\u548c\u5fc3\u7406\u5b78\u5bb6\u958b\u59cb\u5021\u5c0e\u5fc3\u7406\u6cbb\u7642\u6cd5\uff0c\u4f5c\u70ba\u85e5\u7269\u6cbb\u7642\u7684\u8f14\u52a9\u3002<\/p>\n<p>\u5176\u4e2d\u4e00\u7a2e\u6cbb\u7642\u65b9\u6cd5\u53eb\u505a\u8a8d\u77e5\u884c\u70ba\u6cbb\u7642(cognitive behavioral therapy, CBT)\uff0c\u904e\u53bb\u7528\u65bc\u6cbb\u7642\u6182\u9b31\u75c7\u548c\u7126\u616e\u75c7\u3002\u6cbb\u7642\u5e2b\u6703\u8a2d\u8a08\u4e00\u5957\u7a0b\u5e8f\uff0c\u5f15\u5c0e\u75c5\u60a3\u4ee5\u53e6\u4e00\u7a2e\u65b9\u5f0f\u770b\u5f85\u75c5\u75c7\uff0c\u4f86\u6539\u8b8a\u5176\u5c0d\u81ea\u8eab\u884c\u70ba\u7684\u60f3\u6cd5\u3002\u4f8b\u5982\uff0c\u6cbb\u7642\u5e2b\u6703\u9f13\u52f5\u7cbe\u795e\u75c5\u60a3\u505c\u6b62\u58d3\u6291\u5e7b\u89ba\uff0c\u6216\u505c\u6b62\u548c\u8166\u4e2d\u7684\u8072\u97f3\u5c0d\u8a71\uff0c\u4f86\u6e2c\u8a66\u60a3\u8005\u5c0d\u81ea\u8eab\u7684\u63a7\u5236\u7a0b\u5ea6\u3002\u53e6\u5916\uff0c\u6cbb\u7642\u5e2b\u4e5f\u6703\u904b\u7528\u300c\u6b63\u5e38\u5316\u300d(normalization)\u7684\u6280\u5de7\uff0c\u8b93\u60a3\u8005\u77e5\u9053\u4e00\u822c\u4eba\u4e5f\u6703\u7522\u751f\u5e7b\u89ba\u6216\u5e7b\u807d\uff0c\u964d\u4f4e\u5176\u7126\u616e\u611f\u3002<!--more--><\/p>\n<p>\u4e00\u9805\u767c\u8868\u65bc<i>The Lancet<\/i>\u671f\u520a\uff0c\u7531\u66fc\u5fb9\u65af\u7279\u5927\u5b78(University of Manchester)\u81e8\u5e8a\u5fc3\u7406\u5b78\u5bb6\u5b89\u6771\u5c3c\u2027\u83ab\u91cc\u68ee(Anthony Morrison)\u6240\u9818\u929c\u7684\u7814\u7a76\u4e2d\uff0c\u9032\u884c\u4e86\u96a8\u6a5f\u5c0d\u7167\u8a66\u9a57\u3002\u4ed6\u5011\u627e\u4e8674\u540d\u672a\u670d\u7528\u85e5\u7269\u7684\u601d\u89ba\u5931\u8abf\u75c7\u60a3\u8005\uff0c\u5c07\u4ed6\u5011\u96a8\u6a5f\u5206\u6210\u5169\u7d44\uff0c\u4e00\u7d44\u4ee5\u50b3\u7d71\u65b9\u5f0f\u6cbb\u7642(treatment as usual, TAU)\uff1a\u5b9a\u6642\u76e3\u63a7\u3001\u91ab\u5e2b\u6703\u9762\u3001\u5371\u6a5f\u7ba1\u7406\u7b49\u65b9\u5f0f\uff1b\u53e6\u4e00\u7d44\u4ee5\u50b3\u7d71\u65b9\u5f0f\u52a0\u4e0a\u4e00\u5b9a\u6bd4\u4f8b\u7684\u8a8d\u77e5\u884c\u70ba\u6cbb\u7642\u3002\u6bcf\u4e09\u500b\u6708\u89c0\u6e2c\u60a3\u8005\u7684\u75c7\u72c0\u3001\u60c5\u7dd2\u548c\u793e\u4ea4\u80fd\u529b\u3002\u6b77\u7d9318\u500b\u6708\u7684\u8a66\u9a57\u5f8c\uff0c\u7814\u7a76\u5718\u968a\u767c\u73fe\u52a0\u4e0a\u8a8d\u77e5\u884c\u70ba\u6cbb\u7642\u4e00\u7d44\u7684\u60a3\u8005\u75c7\u72c0\u8f03\u8f15\u5fae\uff0c\u6709\u4e2d\u7b49\u7642\u6548\uff0c\u548c\u50b3\u7d71\u6cbb\u7642\u7d44\u4e4b\u9593\u5dee\u7570\u4e26\u4e0d\u5927\uff0c\u7136\u800c\u7814\u7a76\u5718\u968a\u5805\u6301\u5169\u7d44\u7684\u5dee\u7570\u6548\u679c\u91cf\uff0c\u7b49\u540c\u65bc\u5927\u591a\u6578\u6297\u7cbe\u795e\u75c5\u85e5\u7269\u548c\u5b89\u6170\u5291\u6cbb\u7642\u7684\u5dee\u7570\u3002<\/p>\n<p>\u53e6\u5916\uff0c\u7814\u7a76\u5718\u968a\u4e5f\u88dc\u5145\u8aaa\u660e\uff0c\u6709\u8d85\u904e70%\u7684\u601d\u89ba\u5931\u8abf\u75c7\u60a3\u8005\u572818\u500b\u6708\u7684\u7642\u7a0b\u4e2d\u6703\u81ea\u884c\u505c\u85e5\uff0c\u5982\u679c\u80fd\u8b93\u60a3\u8005\u9078\u64c7\u4e00\u4e9b\u4e0d\u9700\u670d\u7528\u85e5\u7269\u7684\u7642\u6cd5\uff0c\u8a8d\u77e5\u884c\u70ba\u6cbb\u7642\u4f3c\u4e4e\u662f\u500b\u9817\u7b26\u5408\u4eba\u6027\u7684\u7b56\u7565\u3002\u83ef\u5a01\u5927\u5b78(University of Warwick)\u7684\u5fc3\u7406\u5b78\u5bb6\u9ea5\u514b\u65af\u2027\u6cca\u5340\u4f0d\u5fb7(Max Birchwood)\u4e5f\u652f\u6301\u6b64\u8aaa\u6cd5\uff0c\u4ed6\u8868\u793a\u6839\u64da\u8fd1\u671f\u7814\u7a76\uff0c\u6297\u7cbe\u795e\u75c5\u85e5\u7269\u7684\u6548\u679c\u5c0d\u65bc\u9752\u5e74\u548c\u5b69\u7ae5\u4f86\u8aaa\u6bd4\u5b89\u6170\u5291\u5dee\uff0c\u975e\u85e5\u7269\u7684\u6cbb\u7642\u65b9\u5f0f\u6216\u8a31\u80fd\u6210\u70ba\u53e6\u4e00\u66ff\u4ee3\u65b9\u6848\u3002<\/p>\n<p>\u4e0d\u904e\u83ab\u91cc\u68ee\u63d0\u9192\uff0c\u5373\u4f7f\u8a8d\u77e5\u884c\u70ba\u6cbb\u7642\u7684\u6210\u6548\u4e0d\u932f\uff0c\u4ed6\u4ecd\u4e0d\u5efa\u8b70\u6240\u6709\u7684\u601d\u89ba\u5931\u8abf\u75c7\u75c5\u60a3\u90fd\u9078\u64c7\u975e\u85e5\u7269\u6cbb\u7642\u7684\u65b9\u5f0f\u3002\u56e0\u70ba\u901974\u540d\u8a66\u9a57\u8005\u90fd\u662f\u5c6c\u65bc\u75c7\u72c0\u8f03\u8f15\u5fae\uff0c\u5c0d\u81ea\u8eab\u53ca\u793e\u7fa4\u7121\u986f\u8457\u5a01\u8105\u7684\u75c5\u60a3\uff0c\u85e5\u7269\u5c0d\u5176\u5f71\u97ff\u8f03\u4e0d\u660e\u986f\u3002\u90e8\u5206\u5b78\u8005\u4e5f\u5efa\u8b70\uff0c\u4ed6\u61c9\u64f4\u5927\u6a23\u672c\u7fa4\uff0c\u8b93\u7814\u7a76\u7d50\u679c\u66f4\u5177\u8aaa\u670d\u529b\u3002<\/p>\n<p>\u8a8d\u77e5\u884c\u70ba\u6cbb\u7642\u5728\u6cbb\u7642\u601d\u89ba\u5931\u8abf\u75c7\u4e0a\u96d6\u5df2\u5c0f\u6709\u6210\u5c31\uff0c\u82f1\u570b\u7684\u91ab\u5b78\u6b0a\u5a01\u751a\u81f3\u5927\u8209\u63a8\u85a6\u6b64\u7642\u6cd5\uff0c\u4f46\u4ecd\u6709\u90e8\u5206\u4eba\u58eb\u5c0d\u5176\u6548\u679c\u5b58\u7591\u3002\u5982\u4e00\u98052014\u5e74\u767c\u8868\u65bc\u82f1\u570b\u7cbe\u795e\u91ab\u5b78\u671f\u520a(The British Journal of Psychiatry)\u7684\u7814\u7a76\u4fbf\u6307\u51fa\uff0c\u904e\u53bb\u6709\u95dc\u8a8d\u77e5\u884c\u70ba\u6cbb\u7642\u6548\u7528\u7684\u8a66\u9a57\u6709\u6975\u5927\u7684\u7455\u75b5\u3002\u82f1\u570b\u8d6b\u7279\u798f\u5fb7\u5927\u5b78(University of Hertfordshire)\u7684\u5fc3\u7406\u5b78\u5bb6\u57fa\u601d\u2027\u6d1b(Keith Laws)\uff0c\u4e5f\u662f\u767c\u8868\u65bc\u82f1\u570b\u7cbe\u795e\u91ab\u5b78\u671f\u520a\u8a8d\u77e5\u884c\u70ba\u7642\u6cd5\u5f8c\u5206\u6790\u8a55\u8ad6\u7814\u7a76\u7684\u4f5c\u8005\uff0c\u4e5f\u8cea\u7591\u83ab\u91cc\u68ee\u7684\u7814\u7a76\u7d50\u679c\u3002\u4ed6\u8868\u793a\u5169\u7d44\u7684\u5dee\u7570\u975e\u5e38\u5c0f\uff0c\u4e14\u8a66\u9a57\u4e2d\u75c7\u72c0\u60e1\u5316\u3001\u88ab\u5f37\u5236\u4f4f\u9662\u7684\u75c5\u60a3\uff0c\u6bd4\u5176\u4ed6\u904b\u7528\u8a8d\u77e5\u884c\u70ba\u7642\u6cd5\u4f46\u540c\u6642\u670d\u7528\u85e5\u7269\u7684\u8a66\u9a57\u591a\u51fa\u8a31\u591a\uff0c\u986f\u793a\u9019\u7a2e\u4e0d\u9700\u670d\u7528\u85e5\u7269\u7684\u7642\u6cd5\u662f\u975e\u5e38\u6709\u98a8\u96aa\u7684\u3002<\/p>\n<p>--<br \/>\n<span style=\"color: #333333;\">\u7814\u7a76\u51fa\u8655\uff1a<strong><a href=\"http:\/\/news.sciencemag.org\/brain-behavior\/2014\/02\/schizophrenia-time-flush-meds\" target=\"_blank\" rel=\"noopener noreferrer\">Schizophrenia: Time to Flush the Meds?<\/a><\/strong><\/span><br \/>\n<span style=\"color: #333399;\"><strong><strong>\u8b6f\u8005\uff1a\u6797\u6021\u5fb7 \u79d1\u6559\u4e2d\u5fc3\u7279\u7d04\u5beb\u624b\uff0c\u5f9e\u4e8b\u79d1\u666e\u6587\u7ae0\u7de8\u8b6f\u3002<\/strong><\/strong><\/span><br \/>\n<span style=\"color: #333399;\"><strong><strong>\u8cac\u4efb\u7de8\u8f2f\uff1aKerina Huang<\/strong><\/strong><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u25a0\u601d\u89ba\u5931\u8abf\u75c7(Schizophrenia<\/p>\n","protected":false},"author":20,"featured_media":17198,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[257,3293],"tags":[1208,1339,566],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2014\/04\/sn-schizophrenia-2.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/17196"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17196"}],"version-history":[{"count":16,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/17196\/revisions"}],"predecessor-version":[{"id":28839,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/17196\/revisions\/28839"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/17198"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17196"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17196"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17196"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}