{"id":15239,"date":"2013-11-12T13:26:50","date_gmt":"2013-11-12T05:26:50","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=15239"},"modified":"2017-07-27T10:53:17","modified_gmt":"2017-07-27T02:53:17","slug":"%e3%80%90%e7%a7%91%e5%ad%b8%e6%96%b0%e7%9f%a5%e3%80%91%e8%ae%93%e9%81%a0%e5%8f%a4%e4%ba%ba%e9%a1%9edna%e8%ae%8a%e3%80%8c%e4%b9%be%e6%b7%a8%e3%80%8d","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=15239","title":{"rendered":"\u3010\u79d1\u5b78\u65b0\u77e5\u3011\u8b93\u9060\u53e4\u4eba\u985eDNA\u8b8a\u300c\u4e7e\u6de8\u300d"},"content":{"rendered":"<p><strong>\u7de8\u8b6f<\/strong>\uff5c\u6c6a\u8283<\/p>\n<figure id=\"attachment_15246\" aria-describedby=\"caption-attachment-15246\" style=\"width: 203px\" class=\"wp-caption alignright\"><a href=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2013\/11\/12.png\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-medium wp-image-15246 \" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2013\/11\/12-203x300.png\" alt=\"12\" width=\"203\" height=\"300\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2013\/11\/12-203x300.png 203w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2013\/11\/12.png 283w\" sizes=\"(max-width: 203px) 100vw, 203px\" \/><\/a><figcaption id=\"caption-attachment-15246\" class=\"wp-caption-text\">\u6211\u7684\u5929\uff0c\u5b78\u8005\u7814\u767c\u51fa\u4e00\u9805\u65b0\u6280\u8853\uff0c\u80fd\u4ee5\u8f03\u4f4e\u7684\u6210\u672c\u5206\u6790\u9060\u53e4\u4eba\u985e\u7684DNA\uff0c\u4f8b\u5982\u9019\u5177\u7955\u9b6f\u6728\u4e43\u4f0a\u3002\uff08\u5716\u7247\u4f86\u6e90\uff1aU.S. Navy\uff09<\/figcaption><\/figure>\n<p>\u79d1\u5b78\u5bb6\u5df2\u5206\u6790\u51fa<a href=\"http:\/\/news.sciencemag.org\/health\/2012\/02\/iceman-was-medical-mess\" target=\"_blank\" rel=\"noopener noreferrer\">5300\u5e74\u524d\u51b0\u4eba\u5967\u8328\uff08\u00d6tzi\uff09<\/a>\u7684\u57fa\u56e0\u9ad4\uff0c\u751a\u81f3\u6700\u8fd1\u53c8\u5b8c\u6210\u5c3c\u5b89\u5fb7\u5854\u4eba\uff08<a href=\"http:\/\/www.sciencemag.org\/content\/340\/6134\/799.summary\" target=\"_blank\" rel=\"noopener noreferrer\">Neandertals<\/a>\uff09\u7684DNA\uff08\u53bb\u6c27\u6838\u7cd6\u6838\u9178\uff09\u5b9a\u5e8f\uff0c\u56e0\u6b64\u4f60\u53ef\u80fd\u4ee5\u70ba\u5982\u4eca\u60f3\u7834\u89e3\u53e4\u4ee3\u4eba\u985e\u7684\u5b8c\u6574\u907a\u50b3\u5bc6\u78bc\u5df2\u662f\u6613\u5982\u53cd\u638c\uff1b\u4f46\u5176\u5be6\u9019\u4e9b\u7814\u7a76\u90fd\u7b97\u7279\u4f8b\uff0c\u56e0\u70ba\u4e0a\u8ff0\u5728\u51b0\u5c01\u5730\u5e95\u6216\u51b0\u5bd2\u6d1e\u7a74\u627e\u5230\u7684\u6b7b\u5c4d\u4fdd\u5b58\u5b8c\u597d\uff0c\u7121\u8ad6\u9aa8\u9abc\u3001\u7259\u9f52\u3001\u982d\u9aee\u6216\u5176\u4ed6\u7d44\u7e54\u53d6\u51fa\u7684DNA\u6a23\u672c\u90fd\u4e7e\u6de8\u7d14\u7cb9\u3002\u4f46\u4e00\u822c\u4f86\u8aaa\uff0c\u5b78\u8005\u6700\u5e38\u627e\u5230\u7684\u4eba\u985e\u907a\u9ab8\u5176\u5be6\u591a\u57cb\u5728\u8f03\u9ad8\u6eab\u7684\u571f\u58e4\u4e2d\uff0c\u907a\u9ab8\u672c\u8eab\u7684\u57fa\u56e0\u5f80\u5f80\u8ddf\u6ecb\u751f\u7d30\u83cc\u7684\u57fa\u56e0\u6df7\u96dc\u5728\u4e00\u8d77\uff0c\u56e0\u6b64\u5206\u6790\u904e\u7a0b\u5341\u5206\u8907\u96dc\u4e14\u6240\u8cbb\u4e0d\u8cb2\u3002\u4e0d\u904e\u6709\u5b78\u8005\u65bc11\u67087\u65e5\u5728\u7f8e\u570b\u4eba\u985e\u907a\u50b3\u5b78\u5354\u6703\uff08American Society of Human Genetics\uff09\u5e74\u6703\u4e0a\u767c\u8868<a href=\"http:\/\/images.cell.com\/images\/EdImages\/AJHG\/ajhg1537.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">\u4e00\u7bc7\u7814\u7a76<\/a>\uff0c\u70ba\u6211\u5011\u5e36\u4f86\u7d14\u5316\u53e4\u4ee3\u4eba\u985eDNA\u6a23\u672c\u7684\u8070\u660e\u65b0\u6280\u8853\u3002<\/p>\n<p>\u79d1\u5b78\u5bb6\u5f9e\u53e4\u4ee3\u4eba\u985e\u7259\u9f52\u6216\u9aa8\u9abc\u63a1\u96c6\u7684\u6a23\u672c\u5f80\u5f80\u8cea\u91cf\u5747\u5dee\uff0c\u53ea\u542b\u6709\u4e0d\u52301%\u7684DNA\uff0c\u5176\u9918\u90fd\u662f\u7d30\u83cc\u7684DNA\u3002\u96d6\u7136\u9019\u7a2e\u300c\u5927\u96dc\u71f4\u300d\u79d1\u5b78\u5bb6\u4e5f\u6709\u8fa6\u6cd5\u5b9a\u5e8f\uff0c\u4f46\u5fc5\u9808\u7528\u5b9a\u5e8f\u6a5f\u5668\u8dd1\u975e\u5e38\u591a\u904d\u624d\u80fd\u7be9\u51fa\u4eba\u985e\u7684DNA\uff0c\u82b1\u8cbb\u904e\u9ad8\uff0c\u56e0\u6b64\u7814\u7a76\u8005\u5f80\u5f80\u6703\u6e96\u5099\u5927\u81f4\u7b26\u5408\u7814\u7a76\u76ee\u6a19\u7684\u73fe\u4ee3\u4eba\u985eDNA\u7247\u6bb5\uff0c\u7528\u9019\u4e9b\u6240\u8b02\u7684\u300c\u57fa\u56e0\u63a2\u91dd\u300d\u4f86\u7be9\u51fa\u6240\u9700\u6a23\u672c\uff08\u73fe\u4ee3\u4eba\u985e\u548c\u9060\u53e4\u4eba\u985e\u7684DNA\u76f8\u4f3c\uff0c\u56e0\u6b64\u63a2\u91dd\u80fd\u5438\u9644\u9060\u53e4\u4eba\u985e\u7684DNA\uff09\u3002\u4f46\u9019\u7a2e\u6280\u8853\u4f9d\u7136\u4e0d\u4fbf\u5b9c\uff0c\u4e5f\u53ea\u80fd\u505a\u5c0f\u90e8\u5206\u7684\u57fa\u56e0\u9ad4\u5b9a\u5e8f\u3002<\/p>\n<p>\u800c\u4e00\u652f\u53f2\u4e39\u4f5b\u5927\u5b78\u7684\u7814\u7a76\u5718\u968a\u63d0\u51fa\u4e86\u6539\u826f\u7684\u65b0\u65b9\u6cd5\u3002\u5361\u7f85\u65af\uff0e\u535c\u65af\u5854\u66fc\u5fb7\uff08Carlos Bustamante\uff09\u7814\u7a76\u5ba4\u7684\u535a\u58eb\u5f8c\u7814\u7a76\u54e1\u6885\u82e5\u8482\u7d72\uff0e\u5361\u672c\u7279\uff08Meredith Carpenter\uff09\u548c\u5e7e\u4f4d\u540c\u4ec1\u6c7a\u5b9a\u5099\u88fdRNA\uff08\u6838\u7cd6\u6838\u9178\uff09\u63a2\u91dd\u800c\u975eDNA\u63a2\u91dd\uff0c\u56e0\u70ba\u6b63\u5982\u535c\u65af\u5854\u66fc\u5fb7\u6240\u89e3\u91cb\u7684\uff0cRNA\u63a2\u91dd\u300c\u8d85\u4fbf\u5b9c\u300d\u3002\u7814\u7a76\u5718\u968a\u627e\u5230\u65b9\u6cd5\u5099\u88fd\u8db3\u4ee5\u6db5\u84cb\u73fe\u4ee3\u4eba\u985e\u5b8c\u6574\u57fa\u56e0\u9ad4\u7684RNA\uff0c\u80fd\u6392\u9664\u975e\u4eba\u985eDNA\uff0c\u6700\u5f8c\u518d\u4f7f\u7528\u9176\u4f86\u964d\u89e3RNA\u63a2\u91dd\uff0c\u7136\u5f8c\u5f97\u5230\u7684\u7d14\u5316\u9060\u53e4\u4eba\u985eDNA\u4fbf\u80fd\u653e\u9032\u57fa\u56e0\u9ad4\u5b9a\u5e8f\u6a5f\u5668\u3002<\/p>\n<p>\u7814\u7a76\u4eba\u54e1\u4ee5\u5341\u5e7e\u7a2e\u9060\u53e4\u4eba\u985e\uff08\u5e74\u4ee3\u5f9e500\u52303500\u5e74\u4e0d\u7b49\uff09\u7684\u9aa8\u9abc\u3001\u7259\u9f52\u548c\u982d\u9aeeDNA\u6a23\u672c\u6e2c\u8a66\u4e0a\u8ff0\u7be9\u9078\u6280\u8853\uff0c\u6240\u5b8c\u6210\u7684\u4eba\u985e\u57fa\u56e0\u5b9a\u5e8f\u662f\u4f7f\u7528\u5927\u96dc\u71f4\u6a23\u672c\u76842\u523013\u500d\u4e4b\u591a\uff0c\u800c\u7cbe\u78ba\u5206\u6790\u4e5f\u80fd\u5f97\u5230\u6a23\u672c\u7684\u984d\u5916\u8cc7\u8a0a\uff0c\u4f8b\u5982\u5148\u524d\u5728\u4fdd\u52a0\u5229\u4e9e\u51fa\u571f\u4e00\u98462500\u5e74\u7684\u9285\u5668\u6642\u4ee3\u4eba\u985e\u7259\u9f52\uff0c\u539f\u672c\u53ea\u80fd\u5206\u6790\u51fa\u9019\u500b\u9060\u53e4\u4eba\u985e\u4f86\u81ea\u6b50\u6d32\uff0c\u4f46\u73fe\u5728\u5df2\u53ef\u5c07\u7a2e\u65cf\u4f86\u6e90\u7e2e\u5c0f\u5230\u4e2d\u6b50\u6216\u5357\u6b50\u7b49\u3002\u6b64\u5916\uff0c\u7814\u7a76\u4eba\u54e1\u4e5f\u5206\u6790\u51fa\u4e00\u5177500\u5e74\u7684\u7955\u9b6f\u6728\u4e43\u4f0a\u4e26\u6c92\u6709\u6b50\u6d32\u8840\u7d71\uff0c\u63a8\u7ffb\u5148\u524d\u897f\u73ed\u7259\u63a2\u96aa\u5bb6\u7684\u8aaa\u6cd5\u3002<!--more--><\/p>\n<p>\u535c\u65af\u5854\u66fc\u5fb7\u5728\u5e74\u6703\u6f14\u8aaa\u4e0a\u8868\u793a\uff0c\u9019\u7a2e\u65b0\u6280\u8853\u300c\u5927\u5e45\u589e\u52a0\u4e86\u80fd\u9032\u884c\u5b8c\u6574\u57fa\u56e0\u9ad4\u5b9a\u5e8f\u7684\u6a23\u672c\u6578\u91cf\u300d\u3002\u535c\u65af\u5854\u66fc\u5fb7\u5718\u968a\u76ee\u524d\u6b63\u5229\u7528\u9019\u9805\u6280\u8853\u9032\u884c\u53e4\u4ee3\u72d7\u7684DNA\u5b9a\u5e8f\uff0c\u76ee\u7684\u662f\u7814\u7a76\u72d7\u7684\u99b4\u5316\u904e\u7a0b\u3002\u6b64\u5916\u4ed6\u5011\u4e5f\u8a8d\u70ba\uff0c\u9019\u9805\u6280\u8853\u9664\u4e86\u80fd\u5e6b\u52a9\u5fae\u751f\u7269\u57fa\u56e0\u9ad4\u5b78\u8005\u6e05\u9664\u6a23\u672c\u4e2d\u7684\u4eba\u985eDNA\u6c61\u67d3\u7269\uff0c\u4e5f\u6709\u52a9\u73fe\u4ee3\u5211\u4e8b\u9451\u8b58\u8655\u7406\u906d\u7d30\u83cc\u6c61\u67d3\u7684\u4eba\u985eDNA\u6a23\u672c\u3002<\/p>\n<p>\u5e74\u6703\u4e0a\uff0c\u7814\u7a76\u5c3c\u5b89\u5fb7\u5854\u4eba\u57fa\u56e0\u9ad4\u7684\u54c8\u4f5b\u5927\u5b78\u907a\u50b3\u5b78\u8005\u5927\u885b\uff0e\u82ae\u5947\uff08David Reich\uff09\u4e5f\u6307\u51fa\uff0c\u9019\u7a2e\u6280\u8853\u300c\u975e\u5e38\u4ee4\u4eba\u8208\u596e\uff0c\u5341\u5206\u6709\u610f\u601d\u300d\uff0c\u4ed6\u4e26\u900f\u904e\u96fb\u5b50\u90f5\u4ef6\u5411\u300a\u79d1\u5b78\u300b\uff08<i>Science<\/i>\uff09\u671f\u520a\u8868\u793a\uff0c\u6709\u4e9b\u5c3c\u5b89\u5fb7\u5854\u4eba\u7684\u6a23\u672c\u5176\u5be6\u6709\u8db3\u5920\u7684DNA\u53ef\u4f9b\u5b9a\u5e8f\uff0c\u4f46\u56e0\u70ba\u906d\u7d30\u83cc\u56b4\u91cd\u6c61\u67d3\uff0c\u56e0\u6b64\u5206\u6790\u7684\u4ee3\u50f9\u904e\u9ad8\u3002\u4ed6\u8aaa\uff1a\u300c\u73fe\u5728\u5c31\u770b\u9019\u7a2e\u65b0\u65b9\u6cd5\u662f\u4e0d\u662f\u80fd\u6210\u70ba\u5be6\u969b\u53ef\u884c\u7684\u6280\u8853\uff0c\u80fd\u7528\u4f86\u9032\u884c\u5b8c\u6574\u57fa\u56e0\u9ad4\u5b9a\u5e8f\uff0c\u5206\u6790\u9019\u4e9b\u56f0\u96e3\u4f46\u91cd\u8981\u7684\u9060\u53e4DNA\u6a23\u672c\u3002\u4f46\u6211\u8a8d\u70ba\u4ed6\u5011\u9019\u500b\u69cb\u60f3\u672c\u8eab\u5c31\u5920\u4ee4\u4eba\u8208\u596e\u4e86\u3002\u300d<\/p>\n<p>--<\/p>\n<pre><span style=\"color: #333333;\"> \u7814\u7a76\u51fa\u8655\uff1a<strong><a href=\"http:\/\/news.sciencemag.org\/archaeology\/2013\/10\/cleaning-ancient-human-dna\">Cleaning Up Ancient Human DNA<\/a><\/strong><\/span><\/pre>\n<p><span style=\"color: #333399;\"><strong><strong>\u8cac\u4efb\u7de8\u8f2f\uff1aKerina Huang<\/strong><\/strong><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7de8\u8b6f\uff5c\u6c6a\u8283 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