{"id":14423,"date":"2013-10-14T18:13:11","date_gmt":"2013-10-14T10:13:11","guid":{"rendered":"https:\/\/case.ntu.edu.tw\/blog\/?p=14423"},"modified":"2017-07-27T11:07:36","modified_gmt":"2017-07-27T03:07:36","slug":"%e5%b0%8d%e8%ab%be%e8%b2%9d%e7%88%be%e7%8d%8e%e7%9a%84%e4%b8%80%e9%bb%9e%e7%9c%81%e6%80%9d","status":"publish","type":"post","link":"https:\/\/case.ntu.edu.tw\/blog\/?p=14423","title":{"rendered":"\u3010\u8afe\u8c9d\u723e\u7cfb\u5217\u3011\u5c0d\u8afe\u8c9d\u723e\u734e\u7684\u4e00\u9ede\u7701\u601d\uff01"},"content":{"rendered":"<p style=\"text-align: center;\"><a href=\"http:\/\/case.ntu.edu.tw\/blog\/?attachment_id=14424\" rel=\"attachment wp-att-14424\"><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-14424\" title=\"nobel-prize-award-overview\" src=\"http:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2013\/10\/nobel-prize-award-overview.jpg\" alt=\"\" width=\"802\" height=\"282\" srcset=\"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2013\/10\/nobel-prize-award-overview.jpg 1000w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2013\/10\/nobel-prize-award-overview-300x105.jpg 300w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2013\/10\/nobel-prize-award-overview-800x280.jpg 800w, https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2013\/10\/nobel-prize-award-overview-600x210.jpg 600w\" sizes=\"(max-width: 802px) 100vw, 802px\" \/><\/a><\/p>\n<p><strong>\u64b0\u6587\u2223 \u5468\u6210\u529f (\u9577\u5e9a\u5927\u5b78\u751f\u7269\u91ab\u5b78\u7cfb\u6559\u6388)<\/strong><\/p>\n<p>\u6bcf\u5e74\u5341\u6708\u8afe\u8c9d\u723e\u734e\u9812\u5e03\u4e4b\u5f8c\uff0c\u5a92\u9ad4\u6216\u662f\u5b78\u754c\u90fd\u6703\u5c0d\u5f97\u734e\u4eba\u7684\u751f\u5e73\u8207\u79d1\u5b78\u4e0a\u7684\u6210\u5c31\u4f5c\u4e00\u4e9b\u4ecb\u7d39\u30022012\u5e74\u4e5f\u4e0d\u4f8b\u5916\uff0c\u4f46\u53e6\u4eba\u611f\u5230\u610f\u5916\u7684\u662f\uff0c\u7acb\u6cd5\u9662\u7684\u653f\u6cbb\u4eba\u7269\u8207\u6211\u5011\u7684\u5b78\u754c\u9818\u8896\u5c45\u7136\u5728\u9019\u500b\u554f\u984c\u4e0a\u4e5f\u78b0\u649e\u51fa\u4e86\u4e00\u6bb5\u8352\u8154\u8d70\u677f\u7684\u706b\u82b1\uff01<\/p>\n<p>2012\u5e7410\u67087\u865f\uff0c\u7acb\u59d4\u9673\u78a7\u6db5\u8cea\u8a62\u4e2d\u7814\u9662\u9662\u9577\u7fc1\u555f\u60e0\uff1a\u53f0\u7063\u672a\u4f86\u5728\u54ea\u4e9b\u9818\u57df\u53ef\u80fd\u7372\u5f97\u8afe\u8c9d\u723e\u734e\uff1f\u7fc1\u555f\u60e0\u958b\u59cb\u7684\u53cd\u61c9\u9084\u7b97\u4e2d\u80af\uff0c\u4ed6\u8aaa\uff1a\u9019\u500b\u4e0d\u662f\u76ee\u6a19\u561b\uff0c\u6c92\u6709\u8fa6\u6cd5\u9810\u6e2c\uff0c\u96a8\u6642\u90fd\u6709\u53ef\u80fd\u767c\u751f\u3002\u4f46\u4ed6\u63a5\u4e0b\u4f86\u6307\u51fa\uff0c\u53f0\u7063\u82e5\u60f3\u596a\u5f97\u570b\u969b\u734e\u9805\uff0c\u5fc5\u9808\u5148\u51dd\u805a\u5167\u90e8\u5171\u8b58\uff0c\u5efa\u7acb\u826f\u597d\u7684\u63d0\u540d\u6a5f\u5236\u3002\u4ed6\u8aaa\uff1a\u300e(\u539f\u97f3)\u5927\u5bb6\u8981\u6709\u4e00\u500b\u5171\u8b58\uff0c\u9019\u500b\u4eba\u6211\u5011\u8981\u628a\u4ed6\u63a8\u4e0a\u570b\u969b\u821e\u53f0\uff0c\u5728\u5167\u90e8\u5c31\u662f\u8981\u5148\u6709\u5171\u8b58\uff0c\u7136\u5f8c\u8981\u6709\u5f37\u529b\u7684\u63d0\u540d\u6a5f\u5236\u51fa\u4f86\u3002\u300f\u4ed6\u9084\u8aaa\u6709\u7684\u734e\u9805\u9700\u8981\u919e\u91c0\uff0c\u5e38\u63d0\u540d\u597d\u5e7e\u6b21\u6700\u5f8c\u624d\u6703\u7372\u734e\uff0c\u5982\u679c\u53ea\u63d0\u540d1\u6b21\u6c92\u7372\u734e\uff0c\u4e0b\u6b21\u53c8\u63db\u63d0\u540d\u5225\u4eba\uff0c\u53ef\u80fd\u6703\u8b93\u4eba\u611f\u89ba\u53f0\u7063\u5c0d\u9019\u500b\u7814\u7a76\u6210\u679c\u6c92\u4fe1\u5fc3\u3002<!--more--><\/p>\n<p>\u8001\u5be6\u8aaa\uff0c\u8afe\u8c9d\u723e\u734e\u7684\u63d0\u540d\u8207\u7372\u734e\u80cc\u5f8c\u7576\u7136\u6703\u6709\u4e00\u4e9b\u5b78\u8853\u653f\u6cbb\u904b\u4f5c\u7684\u75d5\u8de1\u3002\u4f46\u662f\u4ee5\u4e2d\u7814\u9662\u9662\u9577\u7684\u9ad8\u5ea6\uff0c\u5c0d\u8afe\u8c9d\u723e\u734e\u7684\u8a55\u8ad6\u5982\u679c\u53ea\u505c\u7559\u5728\u63d0\u540d\u624b\u6cd5\u6216\u7b56\u7565\u904b\u4f5c\u7684\u5c64\u6b21\uff0c\u90a3\u6211\u771f\u7684\u8981\u5c0d\u81fa\u7063\u5b78\u8853\u672a\u4f86\u7684\u767c\u5c55\u800c\u6182\u5fc3\u4e86\uff01<\/p>\n<p>\u8afe\u8c9d\u723e\u734e\u5176\u5be6\u662f\u897f\u65b9\u5b78\u8853\u793e\u7fa4\u4e2d\u7684\u4e00\u9805\u301d\u793e\u6703\u6d3b\u52d5\u301e\uff0c\u5f9e\u9019\u500b\u89c0\u9ede\u51fa\u767c\uff0c\u6211\u5011\u5012\u662f\u53ef\u4ee5\u5f9e\u6bcf\u5e74\u9812\u734e\u71b1\u9b27\u7684\u8868\u8c61\u5f8c\u9762\uff0c\u770b\u51fa\u4e00\u4e9b\u4eba\u624d\u57f9\u80b2\u4e0d\u540c\u7684\u9580\u9053\u3002\u8b6c\u5982\u8aaa\uff0c\u52a0\u5dde\u628a\u5927\u5b78\u5206\u6210\u7814\u7a76\u3001\u6559\u5b78\u8207\u793e\u5340\u7b49\u4e0d\u540c\u578b\u614b\u7684\u5927\u5b78\u4f5c\u70ba\u653f\u5e9c\u8f14\u52a9\u7d93\u8cbb\u7684\u4f9d\u64da\uff0c\u9019\u500b\u5236\u5ea6\u99ac\u4e0a\u5c31\u6210\u4e86\u6211\u5011\u9ad8\u7b49\u6559\u80b2\u6539\u9769\u7684\u6a19\u7aff\u3002\u6bcf\u570b\u7acb\u5927\u5b78\u6821\u9577\u6717\u6717\u4e0a\u53e3\u7684\u90fd\u662f\u8981\u6210\u70ba\u7814\u7a76\u578b\u5927\u5b78\uff0c\u597d\u50cf\u90a3\u624d\u662f\u57f9\u80b2\u4eba\u30aa\u7684\u552f\u4e00\u65b9\u5f0f\u3002\u5176\u5be6\u5f9e\u904e\u53bb\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u7684\u6559\u80b2\u80cc\u679c\uff0c\u53ef\u4ee5\u770b\u51fa\u4eba\u5bb6\u7684\u5b78\u8853\u9818\u8896\u662f\u600e\u9ebd\u57f9\u990a\u51fa\u4f86\u7684\u3002<\/p>\n<p>\u5982\u679c\u770b\u7f8e\u570b\u8afe\u8c9d\u723e\u751f\u7406\u91ab\u5b78\u734e\u5f97\u4e3b\u662f\u5728\u90a3\u88e1\u5b8c\u6210\u4ed6\u5011\u7684\u5927\u5b78\u6559\u80b2\uff1f\u6211\u5011\u6703\u5f88\u8a1d\u7570\u5730\u767c\u73fe\uff0c\u4ed6\u5011\u591a\u534a\u4f86\u81ea\u5c0f\u7684\u535a\u96c5\u5b78\u9662\uff08Liberal Art College\uff09\uff0c\u5176\u6b21\u662f\u6b77\u53f2\u60a0\u4e45\u4e26\u6df1\u5177\u5b78\u8853\u50b3\u7d71\u7684\u9577\u6625\u6ed5\u76df\u6821\u3002\u52a0\u5dde\u7684\u7814\u7a76\u578b\u5927\u5b78\u5728\u9019\u65b9\u9762\u5e7e\u4e4e\u4ea4\u4e86\u767d\u5377\uff01<\/p>\n<p>\u4ee5\u7f8e\u570b\u751f\u7269\u91ab\u5b78\u754c\u7576\u524d\u6700\u6709\u5f71\u97ff\u529b\u7684\u4e8c\u4f4d\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u70ba\u4f8b\u3002\u66fe\u4efb\u52a0\u5dde\u7406\u5de5\u5b78\u9662\u6821\u9577\u7684\u5df4\u723e\u5e1d\u6469(Baltimore)\u7562\u696d\u65bc\u8cd3\u5dde\u7684\u53f2\u74e6\u65af\u6469\u5b78\u9662(Swarthmore College)\u3001\u800c\u524d\u7f8e\u570b\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662\u9662\u9577\u767c\u6469\u65af(Varmus)\u5247\u4f86\u81ea\u9ebb\u5dde\u7684\u5b89\u8d6b\u65af\u7279\u5b78\u9662(Amherst College)\u3002\u9019\u4e8c\u6240\u5b78\u9662\u90fd\u4e0d\u662f\u6240\u8b02\u7684\u7814\u7a76\u578b\u5927\u5b78\uff0c\u4f46\u662f\u537b\u662f\u4ee5\u300c\u535a\u96c5\u6559\u80b2\u300d\u7a31\u8457\u7684\u5c0f\u5b78\u6821\uff01\u4ed6\u5011\u6ce8\u91cd\u5b78\u751f\u6587\u7406\u6559\u80b2\u7684\u5747\u8861\u767c\u5c55\u8207\u5b78\u7fd2\u80fd\u529b\u7684\u57f9\u990a\u3002\u5b83\u5011\u6c92\u6709\u4ec0\u9ebc\u300c\u901a\u8b58\u8ab2\u7a0b\u300d\uff0c\u4e5f\u6c92\u6709\u8981\u523b\u610f\u5f37\u8abf\u4ec0\u9ebc\u300c\u4eba\u6587\u7d20\u990a\u300d\uff01\u5728\u9019\u4e9b\u5b78\u6821\u88e1\uff0c\u6bcf\u4e00\u9580\u8ab2\u90fd\u662f\u7d2e\u7d2e\u5be6\u5be6\u7684\u53bb\u6559\uff0c\u900f\u904e\u56b4\u683c\u800c\u6df1\u5ea6\u7684\u5b78\u7fd2\u53bb\u958b\u653e\u5b78\u751f\u7684\u5fc3\u9748\u8207\u773c\u754c\u3002\u958b\u767c\u6bcf\u4f4d\u5b78\u751f\u7684\u6f5b\u529b\u8207\u6d1e\u8b58\u662f\u5b83\u5011\u7684\u6559\u80b2\u76ee\u6a19\uff0c\u5c08\u696d\u8a13\u7df4\u5247\u7559\u5230\u7814\u7a76\u6240\u518d\u8aaa\u5427\uff01\u767c\u6469\u65af\u5927\u5b78\u7562\u696d\u6642\u4e3b\u4fee\u662f\u54f2\u5b78\u8207\u82f1\u570b\u6587\u5b78\uff0c\u800c\u5df4\u723e\u5e1d\u6469\u5927\u4e00\u5230\u5927\u4e09\u5728\u751f\u7269\u7cfb\uff0c\u5927\u56db\u5247\u8f49\u5230\u5316\u5b78\u7cfb\u3002\u53f2\u74e6\u65af\u6469\u5b78\u9662\u7d66\u5df4\u723e\u5e1d\u6469\u7684\u4e0d\u662f\u4ec0\u9ebc\u4e86\u4e0d\u5f97\u7684\u79d1\u5b78\u8a13\u7df4\uff0c\u53cd\u800c\u662f\u63d0\u4f9b\u4e00\u500b\u5b8c\u5168\u958b\u653e\u7684\u5b78\u7fd2\u7a7a\u9593\uff0c\u5728\u9019\u88e1\u4ed6\u6240\u63a5\u89f8\u5230\u7684\u4eba\u6587\u7d93\u9a57\u662f\u7121\u53ef\u53d6\u4ee3\u7684\uff01<\/p>\n<p>\u53e6\u5916\u5206\u6790\u6b77\u5e74\u4f86\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u7684\u51fa\u8eab\u8207\u4ed6\u5011\u7814\u7a76\u7684\u4e3b\u984c\uff0c\u6211\u5011\u4e0d\u96e3\u770b\u51fa\u53e6\u4e00\u500b\u6709\u8da3\u7684\u8a0a\u606f\uff0c\u90a3\u5c31\u662f\u5b78\u8853\u767c\u5c55\u7684\u6f6e\u6d41\u4ee5\u53ca\u6240\u8b02\u5b78\u8853\u50b3\u7d71\u7684\u50b3\u627f\u3002\u9019\u88e1\u6700\u6709\u540d\u7684\u4f8b\u5b50\u5c31\u662f\u7f8e\u570b\u8def\u6613\u5e02\u83ef\u76db\u9813\u5927\u5b78\u7684Cori\u592b\u5a66\uff0c\u4ed6\u5011\u57281947\u5e74\u56e0\u70ba\u5728\u7814\u7a76\u809d\u91a3\u4ee3\u8b1d\u800c\u5f97\u734e\u3002\u4ed6\u7684\u624b\u4e0b\u6709\u4e00\u4f4d\u91ab\u751f(E. Suthland)\uff0c\u60f3\u63a2\u8a0e\u809d\u91a3\u4ee3\u8b1d\u5982\u4f55\u53d7\u5230\u8377\u723e\u8499\u7684\u8abf\u63a7\uff0c\u7d50\u679c\u767c\u73fe\u7d30\u80de\u5167\u7684\u4e8c\u7d1a\u8a0a\u865f,\u74b0\u72c0AMP. Suthland \u56e0\u6b64\u57281971\u5e74\u5f97\u734e\u3002Cori \u7684\u53e6\u4e00\u4f4d \u201c\u5c0e\u751f\u201d(E.G. Krebs) \u5247\u56e0\u70ba\u7814\u7a76\u74b0\u72c0AMP \u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u767c\u73fe\u7d30\u80de\u5229\u7528\u86cb\u767d\u8cea\u7684\u78f7\u9178\u5316\u4f5c\u70ba\u8a0a\u865f\u50b3\u905e\u7684\u6a5f\u5236\uff0c\u800c\u57281992\u5e74\u5f97\u734e\u3002\u4ed6\u5011\u4e8c\u4f4d\u5960\u5b9a\u4e86\u7d30\u80de\u8a0a\u865f\u50b3\u905e\u9019\u500b\u7814\u7a76\u9818\u57df\u7684\u57fa\u790e\u3002\u800cSuthland \u53c8\u76f4\u63a5\u5f71\u97ff\u5230Gilman \u53caMurad\u4e8c\u4eba\u7684\u7814\u7a76\u65b9\u5411\u3002 Gilman\u7814\u7a76\u74b0\u72c0AMP\u751f\u6210\u9175\u7d20\u7684\u8abf\u63a7\uff0c\u767c\u73fe\u4e00\u500b\u86cb\u767d\u8ca0\u8cac\u628a\u8377\u723e\u8499\u53d7\u9ad4\u7684\u8a0a\u865f\u50b3\u7d66\u74b0\u72c0AMP\u751f\u6210\u9175\u7d20\uff0c\u9032\u800c\u4fc3\u4f7f\u7d30\u80de\u5167\u74b0\u72c0AMP\u589e\u52a0\u3002Murad\u5247\u662f\u767c\u73fe\u74b0\u72c0GMP\uff0c\u4e26\u9032\u4e00\u6b65\u77ad\u89e3\u74b0\u72c0 GMP \u7684\u751f\u7406\u4f5c\u7528\u3002\u4ed6\u5011\u4e8c\u4eba\u5206\u5225\u5728 1994\u53ca1998\u5e74\u5f97\u734e\u3002\u4eca\u5e74\u8afe\u8c9d\u723e\u5316\u5b78\u734e\u5f97\u4e3bLefkowitz\u5247\u4ecd\u7136\u662f\u9019\u500b\u7814\u7a76\u50b3\u7d71\u7684\u8001\u5175\uff0c\u4ed6\u767c\u5c55\u51fa\u6e2c\u5b9a\u8377\u723e\u8499\u53d7\u9ad4\u7684\u65b9\u6cd5\uff0c\u9032\u800c\u6c7a\u5b9a\u9019\u4e9b\u53d7\u9ad4\u7684\u7d50\u69cb\u3002\u5f9e Cori\u5230 Lefkowitz (1947-2012)\uff0c\u6211\u5011\u53ef\u4ee5\u770b\u51fa\u4e00\u500b\u5b78\u8853\u7814\u7a76\u50b3\u7d71\u7684\u5efa\u7acb\u7684\u4e0d\u6613\uff0c\u4f46\u4ecd\u6709\u5176\u8108\u7d61\u53ef\u5c0b\uff0c\u7d55\u975e\u5728\u9019\u88e1\u5435\u5435\u9b27\u9b27\u4fbf\u53ef\u77ed\u6642\u9593\u5167\u898b\u5f97\u6210\u6548\u7684\uff01<\/p>\n<p>\u8afe\u8c9d\u723e\u734e\u53ea\u53ef\u80fd\u8a95\u751f\u5728\u4e00\u500b\u6709\u6df1\u539a\u7814\u7a76\u57fa\u790e\u8207\u512a\u4e45\u5b78\u8853\u50b3\u7d71\u7684\u571f\u58e4\u4e2d\u3002\u4e0d\u5f9e\u4eba\u624d\u57f9\u80b2\u7684\u57fa\u672c\u9762\u4e0b\u624b\uff0c\u53bb\u5efa\u7acb\u4e00\u500b\u6709\u6df1\u539a\u57fa\u790e\u7684\u7814\u7a76\u793e\u7fa4\uff0c\u7336\u5982\u4e03\u5e74\u4e4b\u75c5\uff0c\u6c42\u4e09\u5e74\u4e4b\u827e\u662f\u6c38\u9060\u4e0d\u53ef\u80fd\u6703\u6709\u7d50\u679c\u7684\uff01<\/p>\n<p style=\"text-align: right;\"><strong>\u4f5c\u8005\u65bc2012\u5e7411\u670829\u65e5\u64b0<\/strong><\/p>\n<p><span style=\"color: #000080; font-weight: bold;\">\u8cac\u4efb\u7de8\u8f2f \u00a0Vita Chen<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u64b0\u6587\u2223 \u5468\u6210\u529f (\u9577\u5e9a\u5927\u5b78\u751f\u7269\u91ab\u5b78\u7cfb\u6559\u6388<\/p>\n","protected":false},"author":20,"featured_media":14424,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1027,3293],"tags":[177],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/case.ntu.edu.tw\/blog\/wp-content\/uploads\/2013\/10\/nobel-prize-award-overview.jpg","_links":{"self":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/14423"}],"collection":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14423"}],"version-history":[{"count":22,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/14423\/revisions"}],"predecessor-version":[{"id":28939,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/posts\/14423\/revisions\/28939"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=\/wp\/v2\/media\/14424"}],"wp:attachment":[{"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14423"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14423"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/case.ntu.edu.tw\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14423"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}